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  • Articles  (32)
  • Springer  (23)
  • BioMed Central  (4)
  • Emerald  (3)
  • Blackwell Science Ltd  (2)
  • 2005-2009  (19)
  • 2000-2004  (9)
  • 1975-1979
  • 1960-1964
  • 1890-1899  (2)
  • 1870-1879  (2)
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  • Articles  (32)
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  • 1
    Electronic Resource
    Electronic Resource
    DNA endoreduplication in maize endosperm cells: the effect of exposure to short-term high temperature (2000)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 23 (2000), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: DNA endoreduplication in Zea mays L. (cv. A619 × W64A) endosperm peaks between 16 and 18 d after pollination (DAP). The physiological function of DNA endoreduplication is not known but it is believed to be important in maize kernel development. In the present study, we investigated how 2, 4 or 6 d of high temperature (35 °C) affected DNA endoreduplication and maize kernel development in comparison with control kernels grown at 25 °C. Data were collected on fresh weight (FW), nuclei number, mitotic index, and DNA endoreduplication. Maize endosperm FW and nuclei number were reduced by exposure to 4 or 6 d of high temperature. At 18 DAP, the 2 d high temperature treatment (HTT) caused a reduction in FW and nuclei number, but had no effect on DNA endoreduplication and average DNA content per endosperm. However, when the exposure to high temperature was increased to 4 or 6 d, FW, nuclei number and the magnitude of DNA endoreduplication were progressively reduced, and the peak mitotic index was delayed compared with the control endosperm. At 18 DAP, the 4 d treatment showed 54·7% of the cells were 3 or 6 C, whereas only 41·2% were 12 C or higher. Six days of high temperature also resulted in a reduction in endosperm FW, nuclei number and a delay in the peak of mitotic index. DNA endoreduplication occurred in the kernels exposed to this treatment, although the magnitude was severely reduced compared with the control kernels. Nuclear DNA content was highly correlated (r= 0·93) with kernel FW, suggesting an important role of DNA endoreduplication in determining endosperm FW. The data suggest that high temperature during endosperm cell division exerted negative effects on DNA endoreduplication by dramatically reducing the nuclei number, leaving fewer nuclei available for DNA endoreduplication. However, the data also suggest that prolonged exposure to high temperature restricts entry of mitotic cells into the endoreduplication phase of the cell cycle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.2000.00564.x
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  • 2
    Electronic Resource
    Electronic Resource
    PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability (2005)
    Oxford, UK : Blackwell Science Ltd
    Molecular microbiology 55 (2005), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: In the yeast Saccharomyces cerevisiae, PKA and Sch9 exert similar physiological roles in response to nutrient availability. However, their functional redundancy complicates to distinguish properly the target genes for both kinases. In this article, we analysed different phenotypic read-outs. The data unequivocally showed that both kinases act through separate signalling cascades. In addition, genome-wide expression analysis under conditions and with strains in which either PKA and/or Sch9 signalling was specifically affected, demonstrated that both kinases synergistically or oppositely regulate given gene targets. Unlike PKA, which negatively regulates stress-responsive element (STRE)- and post-diauxic shift (PDS)-driven gene expression, Sch9 appears to exert additional positive control on the Rim15-effector Gis1 to regulate PDS-driven gene expression. The data presented are consistent with a cyclic AMP (cAMP)-gating phenomenon recognized in higher eukaryotes consisting of a main gatekeeper, the protein kinase PKA, switching on or off the activities and signals transmitted through primary pathways such as, in case of yeast, the Sch9-controlled signalling route. This mechanism allows fine-tuning various nutritional responses in yeast cells, allowing them to adapt metabolism and growth appropriately.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.2004.04429.x
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  • 3
    Electronic Resource
    Electronic Resource
    A delicate managerial challenge: how cooperation and integration affect the performance of teams (2004)
    Bingley : Emerald
    Team performance management 10 (2004), S. 20-25 
    Details
    ISSN: 1352-7592
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Multifunctional teams have become commonplace in new product development (NPD) endeavors. Knowledge on the functioning of such teams, however, remains little. In this article two major principles about how these teams function are investigated, team cooperation and team integration. A theoretical discussion indicates that there is not a clear-cut way to manage team cooperation and team integration in order to achieve high performance. The management of these principles in NPD teams is rather a delicate managerial challenge. These theoretical considerations are statistically examined then. The results show that both team cooperation and team integration are inversely U-shaped related to NPD team performance. In managerial terms the results imply that creating the right level of team cooperation and team integration managers have to balance their actions between two extremes. The article finishes by presenting opportunities how to do so.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/13527590410527559
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  • 4
    Electronic Resource
    Electronic Resource
    Informal contacts and performance in innovation teams (2005)
    Bingley : Emerald
    International journal of manpower 26 (2005), S. 513-528 
    Details
    ISSN: 0143-7720
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Purpose - The paper addresses the effect friendly and friendship relationships among members of innovation teams on the performance of the teams. Design/methodology/approach - The members of innovation teams may develop friendly and friendship relationships over time. In our study, we focus on the effect of the frequency of such non-work relationships on team performance. For this research, we collected full network data on non-work relationships in a sample of 44 innovation teams and investigate how these "friendly and friendship networks" affect the performance of innovation teams. Findings - As result turns out that the frequency of friendly ties has positive as well as negative consequences on team performance, whereas the frequency of friendship ties positively relates to the performance. Research limitations/implications - The results indicate the importance of informal relations for the performance of innovation teams. Further, it is shown that friendly and friendship relations have different theoretical and practical implications. Future research can overcome the limitations of the presented research by concentrating on larger sample sizes and longitudinal research designs. Practical implications - Building on the results of the study managers can better orchestra innovation teams focussing not only on formal but also on informal contacts. The main practical implication is to strive for friendship contacts and to avoid too strong friendly contacts. Originality/value - The study adds knowledge to the research on informal relationships and performance two-fold. First, the findings testify that friendly and friendship contacts are different and not part of the same dimension, and there is strong evidence for the importance of informal contacts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/01437720510625430
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  • 5
    Electronic Resource
    Electronic Resource
    How innovative are Dutch immigrant entrepreneurs?: Constructing a framework of assessment (2002)
    Bingley : Emerald
    International journal of entrepreneurial behaviour & research 8 (2002), S. 69-92 
    Details
    ISSN: 1355-2554
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Asks how innovative Dutch immigrant entrepreneurs are. Since the mid-1980s the number of immigrant firms has more than tripled. This coincides with a huge increase in the number of start-ups in the Dutch economy as a whole. However, international comparisons show that this increase has not resulted in an equal rise in the number of fast growing firms that add value and create employment - the so-called gazelles - and are hence the preferred ideal of policy makers. This raises the question of how innovative the Dutch economy might be. To address this issue, constructs a framework of assessment, derived from the divergent capitalisms approach of Richard Whitley and associates, as this approach offers a useful conceptual instrument to do so. Concludes that, despite appearances, the Dutch institutional setting is not very conducive for value creating innovations, but instead seduces firms, especially small and medium enterprises, to follow reactive strategies. Offers some general remarks on how the conditions for innovation can be improved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/13552550210423732
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  • 6
    Electronic Resource
    Electronic Resource
    Het eisenacher (katheder-socialistisch) congres (1873)
    Springer
    De economist 22 (1873), S. 459-487 
    Details
    ISSN: 1572-9982
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02183330
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  • 7
    Electronic Resource
    Electronic Resource
    Over arbeiderswoningen, naar aanleiding van het nuts-verslag over dat onderwerp (1891)
    Springer
    De economist 40 (1891), S. 700-719 
    Details
    ISSN: 1572-9982
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02213266
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  • 8
    Electronic Resource
    Electronic Resource
    Over arbeiderswoningen, naar aanleiding van het nuts-verslag over dat onderwerp (1891)
    Springer
    De economist 40 (1891), S. 802-837 
    Details
    ISSN: 1572-9982
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02213275
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  • 9
    Electronic Resource
    Electronic Resource
    Het Eisenacher (Katheder-Socialistisch) Congres (1873)
    Springer
    De economist 22 (1873), S. 321-338 
    Details
    ISSN: 1572-9982
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02183323
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  • 10
    Electronic Resource
    Electronic Resource
    Challenges of the LHC: the detector challenge (2004)
    Springer
    The European physical journal 34 (2004), S. 61-65 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjc/s2004-01768-6
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