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  • growth  (2)
  • Humans
  • Mice
  • 1995-1999  (4)
  • 1999  (4)
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  • 1995-1999  (4)
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  • 1
    ISSN: 1573-3017
    Keywords: Tubifex tubifex ; sediment bioassay ; hormesis ; growth ; reproduction ; egestion rates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Toxicity assessment based on sediment chronic bioassays with the aquatic worm Tubifex tubifex was performed at ten contaminated sites in the industrial area of Bilbao (Northern Spain). One control and three reference sites were also included. Tubifex bioassay measures both survival and reproduction impairment. These endpoints have been contrasted and discussed in relation to somatic growth and both individual and total biomass of cocoons. Survival was only affected at one site which was heavily contaminated by organic compounds, mainly PAHs. A group of four severely ecotoxic sediments was characterised by a drastic reduction in number and size of cocoons, and adult somatic growth. In other group of sediments, some significant increases were found for these variables. It is suggested that these increases represent an effect of hormesis. An index of reproductive effort was used to integrate the relationship between somatic growth and reproduction. Values of reproductive effort at the test sediments were lower than those at the control sediment, suggesting a conservative strategy of oligochaete worms which consisted in an investment into somatic line (growth) at the expenses of offspring. Rates of food consumption which were estimated from egestion rates, were low at the contaminated sites. This fact could be related to the low production levels found at these sites and may reflect avoidance feeding behaviour of the oligochaete worms within the sediments. At some reference sites, high production could have resulted from high nutritional quality of sediments, or to an hormetic effect due to low concentration of some chemicals. Results are discussed in relation to toxicity data from sediment three-brood bioassay with Daphnia magna Straus performed separately on the same sediments.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-5176
    Keywords: agar ; Gracilaria tenuistipitata ; growth ; salinity ; seawater pH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Acclimation responses of the red alga Gracilaria tenuistipitata var. liui collected on the northwest coast of Philippines were determined in laboratory setups and outdoor cultivation tanks in Haifa, Israel. Growth under laboratory conditions was influenced by all three variables studied, namely, temperature (20 or 30 °C), salinity (20, 30 or39‰) and seawater pH (6.5, 7.0, 8.0 or ≥ 9.0). In 250 mL flasks lacking pH control growth was influenced by temperature only at 20 ‰, whereas at 39 ‰, growth rates were similar at 20 or 30 °C. In 500 mL cylinders in which pH was controlled, growth rates were significantly different at a pH of 6.5 and 7.0 for all salinities, with maximal rates occurring in 39 ‰. At pH 8.0, and above, growth rates between salinities were similar and reduced to approximately 50% at a pH of 9.0 compared to rates at a pH of 6.5. Photosynthesis responses generally resembled growth responses both, in 250 mL and 500 mL cultures. In 40-L outdoor tanks, weekly growth and agar yields were apparently enhanced by increasing light intensities (up to full sunlight) and nutrient concentrations (up to 0.2 mM PO3 2- and 2.0 mM NH4 +), and rates averaged four times higher than rates determined in the smaller flask cultures. This study shows broad salinity tolerance of G. tenuistipitata var. liui and its ability to sustain growth rates that are among the highest measured for Gracilaria spp. in outdoor cultures.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 1999-08-07
    Description: There is a long-standing controversy regarding the mechanisms that generate the functional subdivisions of the cerebral neocortex. One model proposes that thalamic axonal input specifies these subdivisions; the competing model postulates that patterning mechanisms intrinsic to the dorsal telencephalon generate neocortical regions. Gbx-2 mutant mice, whose thalamic differentiation is disrupted, were investigated. Despite the lack of cortical innervation by thalamic axons, neocortical region-specific gene expression (Cadherin-6, EphA-7, Id-2, and RZR-beta) developed normally. This provides evidence that patterning mechanisms intrinsic to the neocortex specify the basic organization of its functional subdivisions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Miyashita-Lin, E M -- Hevner, R -- Wassarman, K M -- Martinez, S -- Rubenstein, J L -- NS34661-01A1/NS/NINDS NIH HHS/ -- R01 MH49428-01/MH/NIMH NIH HHS/ -- R01 MH51561-01A1/MH/NIMH NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1999 Aug 6;285(5429):906-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, School of Medicine, University of California San Francisco, San Francisco, CA 94143-0984, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10436162" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Axons/chemistry/*physiology ; Cadherins/genetics ; Calbindin 2 ; Carbocyanines ; DNA-Binding Proteins/genetics ; Gene Expression ; Homeodomain Proteins/genetics/physiology ; Immunohistochemistry ; In Situ Hybridization ; Inhibitor of Differentiation Proteins ; Lymphoid Enhancer-Binding Factor 1 ; Mice ; Mutation ; Neocortex/anatomy & histology/*embryology/growth & development/metabolism ; Nerve Fibers/physiology/ultrastructure ; Proteins/genetics ; Receptors, Cell Surface/genetics ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Melatonin ; S100 Calcium Binding Protein G/analysis ; Steroid 17-alpha-Hydroxylase/analysis ; Telencephalon/embryology/growth & development/physiology ; Thalamus/anatomy & histology/*embryology/growth & development/metabolism ; Transcription Factors/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-05-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Martinez-Zaguilan, R -- New York, N.Y. -- Science. 1999 Apr 16;284(5413):433-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10232985" target="_blank"〉PubMed〈/a〉
    Keywords: Angiostatins ; Cell Membrane/*enzymology/metabolism ; Endothelium, Vascular/cytology/*enzymology/metabolism ; Humans ; Hydrogen-Ion Concentration ; Neovascularization, Pathologic ; Peptide Fragments/*metabolism ; Plasminogen/*metabolism ; Proton Pumps ; Proton-Translocating ATPases/*metabolism ; *Vacuolar Proton-Translocating ATPases
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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