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  • ASTROPHYSICS  (114)
  • Animals  (106)
  • ENERGY PRODUCTION AND CONVERSION
  • SPACE VEHICLES
  • 1980-1984  (252)
  • 1983  (252)
  • 1
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    Light and propranolol suppress the nocturnal elevation of serotonin in the cerebrospinal fluid of rhesus monkeys (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-07-29
    Description: Markedly elevated nighttime concentrations of serotonin in rhesus monkey cerebrospinal fluid were reduced to daytime levels by exposing the monkeys to continuous light or to the beta-adrenergic antagonist propranolol. Nighttime elevations of melatonin in cerebrospinal fluid were also suppressed by propranolol and light. Serotonin released in large quantities at night appears to be regulated like melatonin, and may act as a cerebroventricular hormone to influence brain and pituitary function at night.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Garrick, N A -- Tamarkin, L -- Taylor, P L -- Markey, S P -- Murphy, D L -- New York, N.Y. -- Science. 1983 Jul 29;221(4609):474-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6683428" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Circadian Rhythm/drug effects ; Humans ; *Light ; Macaca mulatta ; Male ; Melatonin/physiology ; Propranolol/*pharmacology ; Rats ; Serotonin/*cerebrospinal fluid/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    The thymus-adrenal connection: thymosin has corticotropin-releasing activity in primates (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-12-23
    Description: Endotoxin-free thymosin fraction 5 elevated corticotropin, beta-endorphin, and cortisol in a dose- and time-dependent fashion when administered intravenously to prepubertal cynomolgus monkeys. Two synthetic component peptides of thymosin fraction 5 had no acute effects on pituitary function, suggesting that some other peptides in thymosin fraction 5 were responsible for its corticotropin-releasing activity. In agreement with these observations, total thymectomy of juvenile macaques was associated with decreases in plasma cortisol, corticotropin, and beta-endorphin. These findings indicate that the prepubertal primate thymus contains corticotropin-releasing activity that may contribute to a physiological immunoregulatory circuit between the developing immunological and pituitary-adrenal systems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Healy, D L -- Hodgen, G D -- Schulte, H M -- Chrousos, G P -- Loriaux, D L -- Hall, N R -- Goldstein, A L -- CA 24974/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1983 Dec 23;222(4630):1353-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6318312" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/*blood ; Animals ; Dose-Response Relationship, Drug ; Endorphins/blood ; Female ; Hydrocortisone/blood ; Kinetics ; Macaca fascicularis ; Thymectomy ; Thymosin/analogs & derivatives/*pharmacology ; Thymus Gland/*physiology ; beta-Endorphin
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    The filaments of NGC 1275 - A collision between a galaxy and an accretion flow? (1983)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: Morphological evidence is presented (in the form of 3-A-bandpass Fabry-Perot images made with a CCD camera) that the two bright emission-line systems seen toward the galaxy NGC 1275 arise from a high-velocity impact of a foreground galaxy upon the accretion flow of gas cooling in the center of the Perseus cluster. The uniquely high optical-line luminosity of NGC 1275, in comparison with other central galaxies in clusters observed to have cooling flows, may be explained by energy deposited during the collision. Using additional information from 21-cm and extinction measurements, a rough model of the interaction is developed. Problems remain with this model - such as the likelihood of a gas-rich system penetrating to the cluster center. The kinematic structure of the optically emitting gas shows additional complex structure near the nucleus of NGC 1275.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 2 - Letters to the Editor (ISSN 0004-637X); 275; L27-L31
    Format: text
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    NASA TECHNICAL REPORTS
  • 4
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    Coordinated Einstein and IUE observations of a disparitions brusques type flare event and quiescent emission from Proxima Centauri (1983)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: The Einstein Imaging Particle Counter observed a major X-ray flare in its entirety during a 5-hr period of simultaneous observations, with the IUE, of the dM5e flare star Proxima Centauri in August, 1980. The detailed X-ray light curve, temperature determinations during various intervals, and UV line fluxes obtained before, during, and after the flare indirectly indicate a 'two-ribbon flare' prominence eruption. The calculated ratio of coronal to bolometric luminosity for the event is about 100 times the solar ratio. The Proxima Cen corona is analyzed in the context of static loop models, in light of which it is concluded that less than 6% of the stellar surface seems to be covered by X-ray emitting active regions.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal; vol. 267
    Format: text
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    NASA TECHNICAL REPORTS
  • 5
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    Natural Distribution of the Ixodes dammini spirochete (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-04-15
    Description: Spirochetes believed to be the cause of Lyme disease were isolated from white-footed mice and white-tailed deer, the preferred natural hosts of Ixodes dammini, the tick vector. Evidence suggests that deer act as a reservoir of the disease and provide an overwintering mechanism for both spirochetes and adult ticks. Some tick larvae may acquire the spirochete by transovarial passage and the nymphal stage may transmit the disease to humans.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bosler, E M -- Coleman, J L -- Benach, J L -- Massey, D A -- Hanrahan, J P -- Burgdorfer, W -- Barbour, A G -- New York, N.Y. -- Science. 1983 Apr 15;220(4594):321-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836274" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachnid Vectors/microbiology ; Arthritis, Infectious/microbiology/transmission ; Deer/microbiology/parasitology ; Disease Vectors ; Female ; Humans ; Male ; Peromyscus/microbiology/parasitology ; Spirochaetales/*growth & development ; Ticks/*microbiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Electrical brain stimulation and the localization of cardiopulmonary function (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-11-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Glenn, L L -- New York, N.Y. -- Science. 1983 Nov 4;222(4623):527-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6623095" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*physiology ; Brain Stem/physiology ; Electric Stimulation ; Heart/*innervation ; Humans ; Locomotion ; Lung/*innervation ; *Respiration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Corollary discharge provides accurate eye position information to the oculomotor system (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-16
    Description: The saccadic system accurately compensates for perturbations of eye position produced by microstimulation of the superior colliculus. This requires that information about the stimulation-induced change in eye position be provided by an extraretinal source--either proprioceptive endings in extraocular muscles or a centrally generated corollary discharge. It is shown that compensation remains intact after elimination of extraocular muscle proprioception, demonstrating that corollary discharge provides accurate eye position information.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Guthrie, B L -- Porter, J D -- Sparks, D L -- F32 EY05651/EY/NEI NIH HHS/ -- P30 EY03039/EY/NEI NIH HHS/ -- R01 EY01189/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 16;221(4616):1193-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6612334" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Eye Movements ; Macaca mulatta ; Oculomotor Muscles/*physiology ; Photic Stimulation ; Proprioception ; *Saccades ; Superior Colliculi/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Intermolecular interactions in collagen self-assembly as revealed by Fourier transform infrared spectroscopy (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-06-17
    Description: When a solution of collagen molecules, at neutral pH and moderate ionic strength, is warmed from 4 degrees to 30 degrees C, a spontaneous self-assembly process takes place in which native-type collagen fibers are produced. Events occurring during thermally induced fibrillogenesis process can be monitored, in aqueous media and in real time, by Fourier transform infrared spectroscopic techniques. Tentative assignments of observed spectral bands are given.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jakobsen, R J -- Brown, L L -- Hutson, T B -- Fink, D J -- Veis, A -- New York, N.Y. -- Science. 1983 Jun 17;220(4603):1288-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857249" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Collagen/*metabolism ; Connective Tissue/metabolism ; Rats ; Spectrophotometry, Infrared ; Temperature
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Role of surface-active phospholipids in gastric cytoprotection (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-03-18
    Description: Intragastric administration of a liposomal surfactant suspension markedly reduced acid-induced gastric ulcerogenesis and bleeding in rats. The concentration of surface-active molecules intrinsically present in the gastric mucosa was increased two to six times by administration of 16,16-dimethyl prostaglandin E2. Thus, local accumulation of surface-active phospholipids may be an integral component of the cytoprotective mechanism activated by prostaglandin treatment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lichtenberger, L M -- Graziani, L A -- Dial, E J -- Butler, B D -- Hills, B A -- New York, N.Y. -- Science. 1983 Mar 18;219(4590):1327-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6828859" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Gastric Mucosa/*physiology ; Indomethacin/pharmacology ; Phospholipids/*physiology ; Prostaglandins/physiology ; Rats ; Stomach Ulcer/physiopathology ; Surface-Active Agents
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Genetically obese mice: resistance to metastasis of B16 melanoma and enhanced T-lymphocyte mitogenic responses (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-06-10
    Description: The metastasis of B16 melanoma cells differed significantly in obese (ob/ob) and lean (+/?) female mice of strain C57BL/6J. When the mice were inoculated subcutaneously with melanoma cells at 10 to 11 months of age, the primary tumor grew more slowly in obese than in lean littermates and the frequency of lung metastasis was greatly reduced. When the mice were injected with the cells at 4 to 7 months, the primary tumor grew at the same rate in obese and lean mice, but the obese mice again showed a significantly reduced frequency of lung metastasis. That this effect was related to an enhanced immunocompetence in obese mice was supported by the finding that splenic lymphocytes of ob/ob mice showed three times the proliferative response to the T-cell mitogen concanavalin A compared with the proliferative response of lean control mice. The ob/ob mouse may provide a model for the study of enhanced immunocompetence in obese individuals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Thompson, C I -- Kreider, J W -- Black, P L -- Schmidt, T J -- Margules, D L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1183-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6602379" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Female ; Immunity, Innate ; Lung Neoplasms/immunology ; Male ; Melanoma/*immunology ; Mice ; Mice, Inbred C57BL ; *Mice, Obese ; Neoplasm Metastasis ; Neoplasm Transplantation ; Neoplasms, Experimental/immunology ; Rats ; Receptors, Glucocorticoid/physiology ; T-Lymphocytes/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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