ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Inorganic Chemistry  (6)
  • Life and Medical Sciences  (1)
  • 1980-1984  (7)
  • 1950-1954
  • 1940-1944
  • 1982  (7)
Collection
Keywords
Publisher
Years
  • 1980-1984  (7)
  • 1950-1954
  • 1940-1944
Year
  • 1
    Electronic Resource
    Electronic Resource
    Regulation of herpes simplex virus gene transcription in vitro (1982)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 19 (1982), S. 333-347 
    Details
    ISSN: 0730-2312
    Keywords: in vitro transcription ; HSV-1 ; regulation ; RNA polymerase II ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: We used partially purified RNA polymerase II from uninfected (Pol II) and from herpes simplex virus type 1 (HSV-1) infected HEp-2 cells (Pol II-H) to transcribe HSV-1 DNA in vitro. Gel electrophoretic analysis of the products produced from native HSV-1 DNA yielded weight average chain lengths of 4.0 and 3.5 kb for the Pol II and Pol II-H products, respectively. Blot hybridization analyses of the HSV DNA transcripts showed that both enzymes transcribed RNA from essentially all regions of the genome. However, Pol II preferentially transcribed regions coding for the immediate-early or alpha mRNAs, whereas Pol II-H preferentially copied regions coding for the early (β) and late (γ) gene products. Transcriptional analyses of the cloned HSV-1 Bam HI-Q fragment (containing the thymidine kinase (TK) gene) and its subfragments showed that (1) the major transcripts produced by Pol II-H were distinctly different from those produced by Pol II; (2) Pol II and Pol II-H utilized different promoters for the synthesis of major transcripts; (3) both enzymes produced three minor transcripts that were partially overlapping and in opposite direction to the TK gene; and (4) only Pol II-H initiated transcription from the TK promoter. In contrast, both Pol II and Pol II-H generated an identical set of transcripts from an adenovirus 2 early region DNA fragment. The sizes of the products suggest that RNA processing may be occurring in vitro. These results show that HSV-1 infection alters the in vitro transcriptional specificity of RNA polymerase II and demonstrate that this system should be useful for studying in vitro the regulation of gene transcription.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240190404
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Chirale Dicarbonyl(η5-cyclopentadienyl)-Komplexe von Molybdän und Wolfram mit α-Aminosäure-Anionen (1982)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 115 (1982), S. 846-859 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Chiral Dicarbonyl(η5-cyclopentadienyl) Complexes of Molybdenum and Tungsten with Anions of α-Amino AcidsA series of chiral complexes (η5-C5H5)M(CO)2(L-L′) (M = Mo, W; L-L′ = Gly-O, Sar-O, Me2Gly-O, L-Ala-O, 2-Me-L-Ala-O, L-Val-O, L-Ser-O, L-Thr-O, L-His-O, L-Phe-O, Bzl-L-Phe-O, L-Pro-O, S-Me-L-Cys-O, L-Lys-O, L-Glu-O, L-Cys-O, L-Pen-O) (1a-t, 2a, b, 3, 4) has been prepared and spectroscopically characterized. The diastereomers can be distinguished by their 1H and 13C NMR spectra. They are configurationally stable in solution. The sarcosinato complex 1b can be resolved into the diastereomeric pairs of enantiomers. In alkaline medium a rapid equilibrium of the diastereomers (1:1) is obtained due to isomerization at the coordinated N-atom. The structure of the DL-serinato complex 1i has been determined by X-ray analysis. The unit cell contains two pairs of enantiomers (RMoRC and SMoSC).
    Notes: Eine Reihe von chiralen Komplexen (η5-C5H5)M(CO)2)(L-L′) (M = Mo, W; L-L′ = Gly-O, Sar-O, Me2Gly-O, L-Ala-O, 2-Me-L-Ala-O, L-Val-O, L-Ser-O, L-Thr-O, L-His-O, L-Phe-O, Bzi-L-Phe-O, L-Pro-O, S-Me-L-Cys-O, L-Lys-O, L-Glu-O, L-Cys-O, L-Pen-O) (1a-t, 2a, b, 3, 4) wurde dargestellt und spektroskopisch charakterisiert. Die Diastereomeren lassen sich durch ihre 1H- und 13C-NMR-Spektren unterscheiden. Sie sind in Lösung konfigurationsstabil. Der Sarkosinato-Komplex 1b läßt sich in die diastereomeren Enantiomerenpaare trennen. In alkalischem Medium stellt sich infolge Isomerisierung am koordinierten N-Atom das Diastereomerengleichgewicht 1:1 ein. Die Struktur des DL-Serinato-Komplexes 1i wurde röntgenographisch bestimmt. Die Elementarzelle enthält zwei Enantiomerenpaare (RMoRC und SMoSC).
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19821150303
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Antitumor-aktive cis-Platin(II)-Komplexe mit α-Aminosäureestern und Peptidestern. Struktur von cis-Dichlorobis(glycylglycin-ethylester)platin(II) (1982)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 115 (1982), S. 2256-2270 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Antitumor Active cis-Platinum(II) Complexes with α-Amino Acid Esters and Peptide Esters. X-Ray Structure of cis-Dichlorobis(glycylglycine ethyl ester)platinum(II)A series of cis-platinum(II) complexes X2PtL2 (1-4) (X = halide, 2X = oxalate, malonate; L = α-amino acid ester, peptide ester) has been obtained from Pt42- and L. The dipeptide ester complexes are also accessible via peptide synthesis at the complex from Cl2Pt(NH2CHRCO2H)2 and α-amino acid esters using carbodiimide as coupling agent and the platinum atom as amino protecting group. The complexes Cl2PtL2 with α-amino acid ester ligands have also been prepared from the bis(chelate) compounds cis-Pt(NH2CHRCO2)2 and alcohol in the presence of HCl. The complexes have been characterized by their spectroscopic data, cis-Cl2Pt(GlyGlyOEt)2 (2a) by an X-ray analysis.
    Notes: Eine Reihe von cis-Platin(II)-Komplexen X2PtL2(1-4) (X = Halogenid, 2X = Oxalat, Malonat; L = α-Aminosäureester, Peptidester) wird aus PtX42- und L erhalten. Entsprechende Komplexe mit Dipeptidester-Liganden sind auch durch Peptidsynthese am Komplex aus Cl2Pt-(NH2CHRCO2H)2 und α-Aminosäureestern mit Carbodiimid als Kupplungskomponente und Platin als Aminoschutzgruppe zugänglich. Die Verbindungen Cl2PtL2 mit α-Aminosäureester-Liganden lassen sich auch aus den Bis(chelat)-Komplexen cis-Pt(NH2CHRCO2)2 und Alkohol in Gegenwart von HCl gewinnen. Die cis-Struktur der Verbindungen wurde spektroskopisch, die von Cl2Pt(GlyGlyOEt)2 (2a) durch Röntgenstrukturanalyse nachgewiesen.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19821150621
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Hydrido- und Methyl-Iridium(III)-Verbindungen mit schwach koordinierten anionischen Liganden; ein Weg zu kationischen Iridium(III)-Komplexen (1982)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 115 (1982), S. 2271-2286 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Hydrido- and Methyl-Iridium(III) Complexes with Labile Anionic Ligands; a Route to Cationic Iridium(III) ComplexesHydrido- and methyl-iridium(III) complexes (PPh3)2(CO)ClRIrX (1-4) (R = H, CH3) are formed by oxidative addition of acids HX with poorly coordinating anions X- (X- = O3SCF3-, O3SC4F9-, BF4-) and (CH3)3O+BF4-, respectively, to (PPh3)2(CO)ClIr. The excellent leaving groups X- can be substituted even by weak neutral σ- and π-donors yielding cationic iridium(III) complexes [(PPh3)2(CO)ClRIrB]+X- (5-9) (B = PPh3, CH3CN, H2O, (CH3)2CO, THF, C2H4). The structure of the key tetrafluoroborato complex (PPh3P)2(CO)Cl(H)IrFBF3 (3c) has been determined by X-ray structure analysis.
    Notes: Hydrido- und Methyl-Iridium(III)-Komplexe (PPh3)2(CO)ClRIrX (1-4) (R = H, CH3) entstehen durch oxidative Addition der Säuren HX mit schwach koordinierenden Anionen X- (X- = O3SCF3-, O3SC4F9-, BF4-) bzw. von (CH3)3O+BF4- an (PPh3)2(CO)ClIr. Die ausgezeichneten Abgangsgruppen X- lassen sich auch durch schwache neutrale σ- und π-Donoren unter Bildung der kationischen Komplexe [(PPh3)2(CO)ClRIrB]+X- (5-9) substituieren (B = PPh3, CH3CN, H2O, (CH3)2CO, THF, C2H4). Die Struktur der Schlüsselverbindung (PPh3)2(CO)Cl(H)IrFBF3 (3c) mit koordiniertem Tetrafluoroborat wurde röntgenographisch bestimmt.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19821150622
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Reaktionen von Carbonylmetallhydriden mit Methylthiiran und Struktur von Bis[(η-cyclopentadienyl)-μ-sulfido-sulfidomolybdän] (1982)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 115 (1982), S. 1682-1693 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Reactions of Carbonyl Metal Hydrides with Methylthiirane and Structure of Bis[(η-cyclopentadienyl)-μ-sulfido-sulfidomolybdenum]Reaction of the carbonyl metal hydrides M(η-C5H5)(H)(CO)3 (M = Mo, W), Mn(H)(CO)5, and Fe(H2)(CO)4 with methylthiirane under mild conditions leads to insertion of sulfur into the metal hydrogen bond with formation of the hydrogen sulfido complexes M(η-C5H5)(SH)(CO)3 (M = Mo, W) (1a, b), [Mn(SH)(CO)4]2 (2), and Fe3S2(CO)9 (4), respectively. The molybdenum and tungsten compounds also form the dimeric complexes [M(η-C5H5)S2]2 (M = Mo, W) (6a, b) as well as the dithiolate bridged complex (η-C5H5)Mo[SCH(Me)CH2S]2Mo(η-C5H5) (5). The X-ray structure of anti-6a has been determined.
    Notes: Die Carbonylmetallhydride M(η-C5H5)(H)(CO)3 (M = Mo, W), Mn(H)(CO)5 und Fe(H2)(CO)4 werden mit Methylthiiran unter milden Bedingungen umgesetzt. Dabei entstehen durch Insertion des Schwefelatoms in die Metall-Wasserstoff-Bindung die Hydrogensulfido-Komplexe M(η-C5H5)(SH)(CO)3 (M = Mo, W) (1a, b), [Mn(SH)(CO)4]2 (2) bzw. Fe3S2(CO)9 (4). Die Molybdän- und Wolframverbindungen bilden spontan oder bei höherer Temperatur die zweikernigen Komplexe [M(η-C5H5)S2]2 (M = Mo, W) (6a, b) sowie den Dithiolat-verbrückten Komplex (η-C5H5)Mo[SCH(Me)CH2S]2Mo(η-C5H5) (5). Die Molekülstruktur von anti-6a wurde röntgenographisch bestimmt.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19821150503
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    7-Thiatetracyclo[4.1.0.02,4.03,5]heptan (Benzvalensulfid)  -  Synthese und Reaktionen (1982)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 115 (1982), S. 3213-3223 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: 7-Thiatetracyclo[4.1.0.02,4.03,5]heptane (Benzvalene Sulfide)  -  Synthesis and ReactionsThe reaction of benzvalene (1) with N-(chlorothio)succinimide gives a mixture of the 1:1-adducts 5 and 6, the treatment of which with lithium aluminium hydride transforms 5 into 7-thiatetracyclo[4.1.0.02,4.03,5]heptane (4). Among the electrophiles studied only acids attack the bicyclo[1.1.0]butane portion of 4 and produce 3-thia-trans-tricyclo[4.1.0.02,4]heptanes (9) functionalized in exo-5-position. Peracids transfer an oxygen atom to the sulfur atom of 4 to give the episulfoxide 7. Bromine and chlorine transform 4, probably via the sulfenyl halide intermediates 10, into the bis(trans-3-halotricyclo[3.1.0.02,6]hex-4-yl) disulfides 11 and 12. Mixtures of the disulfides 15 and 16 and the sulfides 19 and 20 are obtained from 4 and thiophenol under the conditions of a radical reaction. Most likely the attack of a phenylthiyl radical at the sulfur atom of 4 initiates the complex reaction sequence.
    Notes: Die Umsetzung von Benzvalen (1) mit N-(Chlorthio)succinimid erbringt ein Gemisch der 1:1-Addukte 5 und 6, bei dessen Behandlung mit Lithiumaluminiumhydrid 5 in 7-Thiatetracyclo[4.1.0.02,4.03,5]heptan (4) übergeht. Als einzige der untersuchten Elektrophile greifen Säuren das Bicyclo[1.1.0]butan-System von 4 an und bringen so exo-5-funktionalisierte 3-Thia-trans-tricyclo[4.1.0.02,4]heptane (9) hervor. Persäuren übertragen auf das S-Atom von 4 ein Sauerstoff-atom unter Bildung des Episulfoxids 7. Brom und Chlor wandeln 4 wohl über die Sulfenylhalogenid-Zwischenstufen 10 in die Bis(trans-3-halogentricyclo[3.1.0.02,6]hex-4-yl)disulfide 11 und 12 um. Unter den Bedingungen einer Radikalreaktion entstehen aus 4 und Thiophenol Gemische der Disulfide 15 und 16 und der Sulfide 19 und 20. Wahrscheinlich löst die Addition eines Phenylthiylradikals an das S-Atom von 4 das komplexe Geschehen aus.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19821151002
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Ein einfacher Weg zu Dithiocarbimidato-Platin(II)-Komplexen (1982)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 115 (1982), S. 1665-1668 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A Simple Route to Dithiocarbimidato Platinum(II) ComplexesDithiocarbimidato complexes 3 are formed by reaction of cis-(Ph3P)2PtCl2 with primary amines in the presence of CS2. BF3 can be added to the lone pair of the N-atom in 3a. The IR and NMR data are reported.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19821150442
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...