Publikationsdatum:
2014-04-09
Beschreibung:
Article Cell cycle regulation of the two major DNA double-strand break repair pathways—NHEJ and HR—is critical for the maintenance of genome integrity. Here, Tomimatsu et al . show that phosphorylation of the nuclease EXO1 by cyclin-dependent kinases affects repair pathway choice by controlling long-range resection. Nature Communications doi: 10.1038/ncomms4561 Authors: Nozomi Tomimatsu, Bipasha Mukherjee, Molly Catherine Hardebeck, Mariya Ilcheva, Cristel Vanessa Camacho, Janelle Louise Harris, Matthew Porteus, Bertrand Llorente, Kum Kum Khanna, Sandeep Burma
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
Permalink