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  • Bücher  (453)
  • 304.2  (348)
  • 615  (105)
  • 1
    Online-Ressource
    Online-Ressource
    Coronary Artery Disease: Therapeutics and Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Beschreibung / Inhaltsverzeichnis: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Kurzfassung: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Materialart: Online-Ressource
    Seiten: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811525179
    Serie: Advances in Experimental Medicine and Biology, 1177
    URL: https://doi.org/10.1007/978-981-15-2517-9
    DOI: 10.1007/978-981-15-2517-9
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    Pediatric Pharmacotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Beschreibung / Inhaltsverzeichnis: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Kurzfassung: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Materialart: Online-Ressource
    Seiten: VIII, 538 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030504946
    Serie: Handbook of Experimental Pharmacology, 261
    URL: https://doi.org/10.1007/978-3-030-50494-6
    DOI: 10.1007/978-3-030-50494-6
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Online-Ressource
    Online-Ressource
    Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Kurzfassung: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Materialart: Online-Ressource
    Seiten: VIII, 425 p. 70 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030685102
    Serie: Handbook of Experimental Pharmacology, 264
    URL: https://doi.org/10.1007/978-3-030-68510-2
    DOI: 10.1007/978-3-030-68510-2
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Online-Ressource
    Online-Ressource
    Organotypic Models in Drug Development (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Beschreibung / Inhaltsverzeichnis: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Kurzfassung: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Materialart: Online-Ressource
    Seiten: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030700638
    Serie: Handbook of Experimental Pharmacology, 265
    URL: https://doi.org/10.1007/978-3-030-70063-8
    DOI: 10.1007/978-3-030-70063-8
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Online-Ressource
    Online-Ressource
    Vaccination Strategies Against Highly Variable Pathogens (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Beschreibung / Inhaltsverzeichnis: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Kurzfassung: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Materialart: Online-Ressource
    Seiten: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030580049
    Serie: Current Topics in Microbiology and Immunology, 428
    URL: https://doi.org/10.1007/978-3-030-58004-9
    DOI: 10.1007/978-3-030-58004-9
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Online-Ressource
    Online-Ressource
    Drug Stability and Chemical Kinetics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Beschreibung / Inhaltsverzeichnis: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Kurzfassung: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Materialart: Online-Ressource
    Seiten: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811564260
    URL: https://doi.org/10.1007/978-981-15-6426-0
    DOI: 10.1007/978-981-15-6426-0
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Online-Ressource
    Online-Ressource
    Handbook of 200 Medicinal Plants : A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Pharmacy. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Medicinal Chemistry.
    Beschreibung / Inhaltsverzeichnis: Abelmoschus maschatus -- Abrus precatorius -- Abutilon indicum -- Acacia catechu -- Acacia nilotica (A. arabica) -- Achillea millefolium -- Achyranthes aspera -- Aconitum napellus -- Acorus calamus -- Adiantum venustum (Adiantun capillus-veneris) -- Aegle marmelos -- Agrimonia eupatorium.-Alhagi maurorum -- Alkanna tinctoria -- Allium cepa -- Allium sativum -- Aloe vera -- Alpinia galangal -- Alpinia officinarum -- Alstonia scholaris -- Althaea officinalis -- Ammi majus -- Anacardium occidentale -- Anacyclus pyrethrum -- Andrographis paniculata -- Anethum graveolens -- Anthemis nobilis -- Apium graveolens -- Argemone Mexicana -- Aristolochia bracteolata -- Aristolochia fontanesii (A. longa) -- Aristolochia indica -- Aristolochia rotunda -- Artemisia absinthium -- Artemisia vulgaris -- Asparagus adscendens -- Asparagus officinalis -- Asparagus racemosus -- Atropa belladonna -- Azadirachta indica -- Bacopa monnieri -- Bauhinia tomentosa -- Berberis Aristata -- Berberis vulgaris -- Bombyx mori -- Borago officinalis -- Boswellia serrata -- Brassica nigra -- Butea monosperma -- Caccinia macranthera var. glauca (C. glauca) -- Caesalpinia bonduc (Caesalpinia bonducella) -- Cannabis sativa -- Capparis spinosa -- Cardiospermum halicacabum -- Carthamus tinctorius -- Carum carvi -- Cassia fistula -- Catharanthus roseus -- Celastrus paniculatus -- Centaurea behen -- Centella asiatica -- Chamaecrista absus (Cassia absus) -- Chamaemelum nobile (Anthemis nobilis) -- Cheilocostus speciosus (Costus Speciosus) -- Cichorium intybus -- Cinnamomum camphora -- Cinnamomum cassia -- Cinnamomum verum (C. zeylanicum) -- Citrullus colocynthis -- Clitoria ternatea -- Colchicum autumnale -- Colchicum luteum -- Commiphora gileadensis (C. opobalsamum) -- Commiphora myrrha -- Commiphora wightii (C. mukul) -- Convolvulus scammonia -- Cotoneaster nummularius -- Crocus sativus -- Croton tiglium -- Cullen corylifolium (Psoralea corylifolia) -- Cuminum cyminum -- Curcuma aromatica -- Curcuma longa -- Curcuma zedoaria -- Cuscuta chinensis -- Cuscuta reflexa -- Cydonia oblonga -- Cymbopogon schoenanthus -- Cyperus rotundus -- Datura stramonium -- Delphinium denudatum -- Dolichousnea longissimi (Usnea longissima) -- Doronicum pardalianches -- Embelia ribes -- Euphorbia hirta -- Euphorbia resinifera -- Ferula assa-foetida -- Ficus carica -- Ficus racemosa -- Foeniculum vulgare -- Fumaria officinalis -- Gentiana lutea -- Glycyrrhiza glabra -- Gymnema sylvestre -- Helleborus niger -- Hemidesmus Indicus -- Hibiscus rosa-sinensis -- Holarrhena pubescens (Holarrhena antidysenterica) -- Hyoscyamus niger -- Hyssopus officinalis -- Illicium verum -- Iris germanica -- Juniperus communi -- Justicia adhatoda (Adhatoda vasica) -- Lactuca sativa -- Lavandula stoechas -- Lawsonia inermis -- Lepidium sativum -- Linum usitatissimum -- Lupinus albus -- Malva sylvestris -- Marrubium vulgare -- Matricaria chamomilla -- Melia azedarach -- Melilotus officinalis -- Melissa officinalis -- Mesua ferrea -- Momordica charantia -- Moringa oleifera -- Myristica fragrans -- Myrtus communis -- Nageia nagi -- Nepeta cataria -- Nigella sativa -- Ocimum basilicum -- Ocimum gratissimum -- Ocimum tenuiflorum (Ocimum sanctum -- Operculina turpethum -- Paeonia emodi -- Pandanus odorifer (Pandanus Odoratissimus) -- Papaver somniferum -- Persicaria bistorta -- Phyllanthus emblica (Emblica officinalis) -- Picrorhiza kurroa -- Pimpinella anisum -- Piper cubeba -- Piper nigrum -- Pistacia lentiscus -- Plantago major -- Plantago ovata -- Plumbago zeylanica -- Polygonum aviculare -- Portulaca oleracea -- Quercus infectoria -- Rauvolfia serpentina -- Rheum emodi -- Rheum officinale -- Ricinus communis -- Rubia cordifolia -- Rumex vesicarius -- Ruta graveolens -- Salix caprea -- Salvia officinalis -- Santalum album -- Saussurea lappa -- Semecarpus anacardium -- Senna alexandrina -- Senna occidentalis -- Senna tora -- Sida cordifolia -- Smilax china;- Solanum americanum (S. nigrum) -- Sterculia urens -- Strychnos nux-vomica -- Swertia chirata -- Symplocos racemosa -- Syzygium cumini (Eugenia jambolana) -- Tamarindus indica -- Taraxacum officinale -- Taxus baccata -- Tephrosia purpurea -- Terminalia bellirica -- Terminalia chebula -- Thymus vulgaris -- Tinospora cordifolia -- Trachyspermum ammi (Ptychotis coptica) -- Tribulus terrestris -- Trigonella foenum-graecum -- Tussilago farfara -- Valeriana jatamansi (Nardostachys jatamansi) -- Verbena officinalis -- Vernonia anthelmintica (Baccharoides anthelmintica) -- Vigna unguiculata (Dolichos biflorus) -- Viola odorata -- Viscum album -- Withania somnifera -- Wrightia tinctoria -- Zingiber officinale -- Zingiber zerumbet -- Ziziphus jujuba -- Abbreviations -- Glossary -- Ayurvedic Terms of Diseases -- List of Referenced Books -- Index.
    Kurzfassung: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.
    Materialart: Online-Ressource
    Seiten: XXX, 2156 p. 199 illus., 198 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030168070
    URL: https://doi.org/10.1007/978-3-030-16807-0
    DOI: 10.1007/978-3-030-16807-0
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
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    Therapeutic Applications of Dopamine D3 Receptor Function : New Insight After 30 Years Of Research (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Preface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson’s Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging.
    Kurzfassung: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
    Materialart: Online-Ressource
    Seiten: VIII, 275 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031230585
    Serie: Current Topics in Behavioral Neurosciences, 60
    URL: https://doi.org/10.1007/978-3-031-23058-5
    DOI: 10.1007/978-3-031-23058-5
    DDC: 615
    Sprache: Englisch
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  • 9
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    Online-Ressource
    Approaching Complex Diseases : Network-Based Pharmacology and Systems Approach in Bio-Medicine (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Kurzfassung: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Materialart: Online-Ressource
    Seiten: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030328573
    Serie: Human Perspectives in Health Sciences and Technology, 2
    URL: https://doi.org/10.1007/978-3-030-32857-3
    DOI: 10.1007/978-3-030-32857-3
    DDC: 615
    Sprache: Englisch
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  • 10
    Online-Ressource
    Online-Ressource
    Pharmacology of Potassium Channels (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Human physiology. ; Neurosciences. ; Pharmacology. ; Human Physiology. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.
    Kurzfassung: The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .
    Materialart: Online-Ressource
    Seiten: VIII, 545 p. 70 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030840525
    Serie: Handbook of Experimental Pharmacology, 267
    URL: https://doi.org/10.1007/978-3-030-84052-5
    DOI: 10.1007/978-3-030-84052-5
    DDC: 615
    Sprache: Englisch
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  • 11
    Online-Ressource
    Online-Ressource
    Nutritional Toxicology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Nutrition   . ; Food science. ; Pharmacology. ; Nutrition. ; Food Science.
    Beschreibung / Inhaltsverzeichnis: 1 Preface -- 2 Effects of Nutrients/nutrition on Toxicants/toxicity -- 3 Effects of Xenobiotics on Nutrition -- 4 Effects of Antinutritional Factors on the Digestibility, Bioavailability and Quality of Protein -- 5 Natural Toxicants Originating from Food/Diet -- 6 Food contaminants -- 7 Food additives -- 8 Food contact materials -- 9 Genetically modified food -- 10 Tolerable upper limits of nutrients -- 11 Risk assessment and Risk-benefit assessment -- 12 Nutrients/Nutrition and Drug Interaction -- 13 Phytochemicals and Health -- 14 Adverse Effects of Phytochemicals.
    Kurzfassung: This book provides a broad overview of the chemicals in food that have the potential to induce adverse health effects. Nutritional Toxicology is an interaction of nutrition, toxicology, biochemistry and food science, etc. Its main research scope involves the effects of nutrients on metabolisms of toxicants and their mechanisms, the interaction of the toxicants and contaminants originated from diet with nutrients and nutrition process, the adverse health outcome of nutrients excess, as well as methodology of research and related food and nutrition regulation process. Also the risk assessment of toxicants and contaminants in foods, and risk benefit assessment of nutrients (dietary supplementation) has become an emerging topic. This book provides novel and provocative insights into the fields of nutrition, food science and toxicology. It also offers a state-of-the-art report on recent discoveries concerning nutritional toxicology and where the field is going. It mainly focuses on advances made over the past 20 years. It will benefit graduate students, researchers and food and nutrition related regulation parties.
    Materialart: Online-Ressource
    Seiten: X, 384 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811908729
    URL: https://doi.org/10.1007/978-981-19-0872-9
    DOI: 10.1007/978-981-19-0872-9
    DDC: 615
    Sprache: Englisch
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  • 12
    Online-Ressource
    Online-Ressource
    Network Pharmacology (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Pharmacy. ; Bioinformatics. ; Pharmacology. ; Pharmacy. ; Bioinformatics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. 'Network Target' Theory and Network Pharmacology -- Chapter 2. Application of Network Pharmacology Based on Artificial Intelligence Algorithm in Drug R & D -- Chapter 3. Commonly used Network Pharmacology Database -- Chapter 4. Commonly used Network Pharmacology Software -- Chapter 5. Network Pharmacology and TCM Modernization Case Studies -- Chapter 6. Network Pharmacology and Modern Drug R & D Cases -- Chapter 7. Drug-based Network Pharmacology Practice Process -- Chapter 8. Disease-based Network Pharmacology Practice Process -- Chapter 9. Drug-disease-based Network Pharmacology Practice Process.
    Kurzfassung: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
    Materialart: Online-Ressource
    Seiten: XVII, 468 p. 163 illus., 119 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811607530
    URL: https://doi.org/10.1007/978-981-16-0753-0
    DOI: 10.1007/978-981-16-0753-0
    DDC: 615
    Sprache: Englisch
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  • 13
    Online-Ressource
    Online-Ressource
    Environment and Female Reproductive Health (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Midwifery. ; Public health. ; Pharmacology. ; Midwifery. ; Public Health.
    Beschreibung / Inhaltsverzeichnis: Part I Environmental Harmful Factors -- 1 Introduction to Environmental Harmful Factors -- Part II Female Reproductive Processes and Diseases -- 2 Introduction of Female Reproductive Processes and Reproductive Diseases -- Part III Effects of Environmental Factors on Reproductive Process -- 3 The Influence of Environmental Factors on Ovarian Function, Follicular Genesis, and Oocyte Quality -- 4 Effects of environment and lifestyle factors on premature ovarian failure -- 5 Effects of Environment and Lifestyle Factors on Anovulatory Disorder -- 6 Effects of Cigarette Smoking on Preimplantation Embryo Development -- 7 Toxicical effects of BPDE on dysfunctions of female trophoblast cells -- 8 The Roles of Stress-Induced Immune Response in Female Reproduction -- 9 Effects of Environmental EDCs on Oocyte Quality, Embryo Development and the Outcome in Human IVF Process -- Part IV Effects of Environmental Factors on Reproductive Diseases -- 10 Effects of environmental endocrine-disrupting chemicals on female reproductive health -- 11 Definition and Multiple Factors of Recurrent Spontaneous Abortion -- 12 The Variations of Metabolic Detoxification Enzymes Lead to Recurrent Miscarriage and their Diagnosis Strategy -- Part V Effects of Environmental Factors on Fertility Preservation -- 13 The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.
    Kurzfassung: This book will focus on the harmful effect of environmental toxins on female reproductive health. Reproduction is the basis of the continuation of human beings, and environment is the basis of human survival. However, environmental pollution has become a potential risk factor for human reproductive health, which not only leads to many chronic diseases, but also causes certain harm to reproductive health. Compared to male reproduction, female reproductive process is more complex, the reproductive system is more fragile, and is more vulnerable to be damaged. The aim of this book is to review the research progress, to address the challenges, and to stimulate the development in the direction of environment and female reproductive health.
    Materialart: Online-Ressource
    Seiten: XI, 313 p. 13 illus., 10 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789813341876
    Serie: Advances in Experimental Medicine and Biology, 1300
    URL: https://doi.org/10.1007/978-981-33-4187-6
    DOI: 10.1007/978-981-33-4187-6
    DDC: 615
    Sprache: Englisch
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  • 14
    Online-Ressource
    Online-Ressource
    Organic Cation Transporters in the Central Nervous System (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Human physiology. ; Molecular biology. ; Pharmacology. ; Human Physiology. ; Molecular Biology.
    Beschreibung / Inhaltsverzeichnis: General Overview of Organic Cation Transporters in Brain -- Organic Cation Transporter Expression and Function in the CNS -- Genetic and Epigenetic Regulation of Organic Cation Transporters -- Experimental Methods for Investigating Uptake 2 Processes In Vivo -- Substrates and inhibitors of OCTs and PMAT and therapeutic implications -- Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications -- Organic Cation Transporters in Brain Catecholamine Homeostasis -- The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances -- Organic Cation Transporters in Psychiatric Disorders -- Organic Cation Transporters and Nongenomic Glucocorticoid Action -- Brain Plasma Membrane Monoamine Transporter in Health and Disease -- Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications -- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery.
    Kurzfassung: Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics. The chapter, “General Overview of Organic Cation Transporters in Brain”, of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Materialart: Online-Ressource
    Seiten: XII, 328 p. 70 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030829841
    Serie: Handbook of Experimental Pharmacology, 266
    URL: https://doi.org/10.1007/978-3-030-82984-1
    DOI: 10.1007/978-3-030-82984-1
    DDC: 615
    Sprache: Englisch
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  • 15
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    Online-Ressource
    The Carbonic Anhydrases: Current and Emerging Therapeutic Targets (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy.
    Beschreibung / Inhaltsverzeichnis: Dedication -- Preface.-The carbonic anhydrases in health and disease -- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets -- Targeting carbonic anhydrases in vascular and pulmonary disease -- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema -- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders -- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes -- An overview of carbonic anhydrase-related neoplasms -- The carbonic anhydrase IX interactome and the regulation of cancer progression -- Carbonic anhydrase IX: current and emerging therapies -- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents -- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening -- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.
    Kurzfassung: This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.
    Materialart: Online-Ressource
    Seiten: XII, 288 p. 38 illus., 22 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030795115
    Serie: Progress in Drug Research, 75
    URL: https://doi.org/10.1007/978-3-030-79511-5
    DOI: 10.1007/978-3-030-79511-5
    DDC: 615
    Sprache: Englisch
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  • 16
    Online-Ressource
    Online-Ressource
    Pharmacology of the WNT Signaling System (2021)
    Cham :Springer International Publishing :
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    Schlagwort(e): Pharmacology. ; Physiology. ; Oncology. ; Neurosciences. ; Developmental biology. ; Pharmacology. ; Physiology. ; Oncology. ; Neuroscience. ; Developmental Biology and Stem Cells.
    Beschreibung / Inhaltsverzeichnis: Pharmacological thinking in WNT signaling -- Controlling WNT Signaling Specificity and implications for targeting WNTs pharmacologically -- WNTs on exosomes -- Strategies to target LRPs in WNT signaling -- Targeting the receptor tyrosine kinase ROR1 by small molecules -- Assessing WNT binding and Frizzled activation employing genetically encoded, biophysical sensors -- Disheveled proteins as crucial mediators of WNT signaling -- Destruction complex and regulation of CTNNB1 -- Strategies to therapeutically target WNT/PCP like signaling in disease -- Mining natural compounds to target WNT signaling - from mushrooms to corals -- FZD7 as a therapeutic target in intestinal cancer -- Targeting oncogenic WNT signaling with WNT derived peptides -- Targeting WNT signaling in lung pathology -- The role of WNT signaling in osteoarthritis and the therapeutic potential of its pharmacological targeting -- WNT signaling in Alzheimers disease and other neurodegenerative disorders - opportunities for therapy? -- Targeting WNT signaling as a risk.
    Kurzfassung: This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulation, tissue homeostasis and repair. Dysfunction of this evolutionarily conserved signaling system leads to many diseases including developmental disorders, diverse forms of cancer, fibrosis, neurodegenerative disease and many more. The WNT signaling system is built upon 19 mammalian, secreted WNT lipoglycoproteins that interact with a plethora of distinct receptors, such as the G protein-coupled receptors called Frizzleds (FZD1-10), LDL receptor-like proteins (LRP5/6), receptor tyrosine kinases (ROR1, 2, RYK and PTK7). In addition, WNT pathways are tightly regulated by many secreted and cell-intrinsic negative regulators, such as soluble FZD-related proteins (SFRPs), Dickkopfs (DKKs), WNT-inhibitory proteins, TIKI, RNF43 and more. Understanding the basic mechanism in terms of receptor-ligand interaction, receptor selectivity, signal initiation and desensitization remain poorly understood, even though substantial advances have been made the recent years. Due to the involvement of the WNT signaling system in human disease, it appears obvious to target diverse branches pharmacologically and therapeutically. However, given the complexity of the system and its importance for stem cell regulation and tissue maintenance, therapy comes with obvious risks for severe side effects. The field is addressing the challenge to identify suitable targets and selective compounds for therapy allowing disease-selective therapeutic effects and balancing unwanted side effects. This book summarizes the current understanding of the basic and applied pharmacology in the WNT signaling system and bridges disciplines such as pharmacology, physiology, neurosciences, oncology and drug development.
    Materialart: Online-Ressource
    Seiten: VIII, 422 p. 70 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030854997
    Serie: Handbook of Experimental Pharmacology, 269
    URL: https://doi.org/10.1007/978-3-030-85499-7
    DOI: 10.1007/978-3-030-85499-7
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 17
    Online-Ressource
    Online-Ressource
    The Art of Carbohydrate Analysis (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Chemistry, Organic. ; Food science. ; Biotechnology. ; Pharmacology. ; Organic Chemistry. ; Food Science. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 The World of Carbohydrates -- Chapter 2 Basic Knowledge of Glycobiology -- Chapter 3 Carbohydrates involved in Diseases -- Chapter 4 Detection of Carbohydrate by Colorimetric Methods -- Chapter 5. Analytical Techniques to Study Carbohydrates -- Chapter 6 Monosaccharide Composition Analysis -- Chapter 7 Carbohydrate Analysis of Glycoconjugates -- Chapter 8 Structural Characterization of Released Glycans -- Chapter 9 Analysis of Sialic Acids -- Chapter 10 Carbohydrate Microarray Technology -- Chapter 11 Analysis of Carbohydrates by Mass Spectrometry -- Chapter 12 Analysis of Carbohydrates by Nuclear Magnetic -- Chapter 13 Glycobioinformatics -- Chapter 14 Concluding Remarks. .
    Kurzfassung: The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.
    Materialart: Online-Ressource
    Seiten: XXV, 350 p. 117 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030777913
    Serie: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-77791-3
    DOI: 10.1007/978-3-030-77791-3
    DDC: 615
    Sprache: Englisch
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  • 18
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    Online-Ressource
    Polypharmacology : Principles and Methodologies (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Neuropharmacology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Neuropharmacology.
    Beschreibung / Inhaltsverzeichnis: PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles -- Basics of Polypharmacology -- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C) -- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF) -- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD) -- Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD -- Anti-cancer Polypharmacology -- Cardiovascular Polypharmacology -- Neuronal Polypharmacology -- Pulmonary Polypharmacology -- Polypharmacology of Metabolic Disease -- Polypharmacology of Infectious Disease -- Polypharmacology of Inflammation -- Anti-psychotics Polypharmacology -- Anti-aging Polypharmacology -- Polypharmacology in Drug Repurposing -- Polypharmacology and Unintended Drug Promiscuity -- Polypharmacology Pharmacokinetics -- The Future of Polypharmacology -- PART II. Polypharmacology in New Drug Development: Strategies and Protocols -- Designed MTSD Discovery Process -- Designed MTSD Discovery Strategies -- Designed MTSD Discovery Technologies -- Designed MTSD Discovery Databases -- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation -- Designed MTSD Lead Identification and Optimization -- Designed MTSD Discovery Protocols -- Natural Products in MTSD Discovery -- Polypharmacology Procedures for Drug Repurposing -- Polypharmacology Procedures for Drug Promiscuity Discovery.
    Kurzfassung: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on Polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology on Polypharmacology. This book aims to meet the needs of making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of Polypharmacology targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy. Rich in illustrations and tables to showcase readers for better understanding the concepts and technologies related to Polypharmacology; Provides comprehensive, systemic, holistic, and explicit explanations and discussion of the fundamental knowledge, background information, conceptual evolution, and updated methodology, as well as in-depth mechanisms behind the knowledge and methodology of Polypharmacology; Main emphasis on rationally designed Polypharmacology or “multi-target, single-drug (MTD)” pharmacology, which represents the major future direction of Polypharmacology and Pharmacology; Describes the clinical applications of Polypharmacology to various human diseases in the clinical and preclinical settings; Contains a wide collection of the state-of-the-art Polypharmacology technologies applicable to the designed MTD discovery and the step-by-step descriptions of drug discovery process applying Polypharmacology principles and methodologies.
    Materialart: Online-Ressource
    Seiten: XXV, 856 p. 12 illus., 9 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031049989
    URL: https://doi.org/10.1007/978-3-031-04998-9
    DOI: 10.1007/978-3-031-04998-9
    DDC: 615
    Sprache: Englisch
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  • 19
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    Online-Ressource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Kurzfassung: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Materialart: Online-Ressource
    Seiten: X, 655 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Sprache: Englisch
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  • 20
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    Data Monitoring Committees (DMCs) : Past, Present, and Future (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Beschreibung / Inhaltsverzeichnis: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Kurzfassung: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Materialart: Online-Ressource
    Seiten: XII, 111 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031287602
    URL: https://doi.org/10.1007/978-3-031-28760-2
    DOI: 10.1007/978-3-031-28760-2
    DDC: 615
    Sprache: Englisch
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  • 21
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    Online-Ressource
    Macrophage Targeted Delivery Systems : Basic Concepts and Therapeutic Applications (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Pharmaceutical chemistry. ; Cytology. ; Toxicology. ; Immunology. ; Pharmacology. ; Pharmaceutics. ; Cell Biology. ; Toxicology. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: Part I Anatomy, Physiology and Pharmacology of Macrophages -- Introduction to Anatomy and Physiology of Macrophages from Drug Delivery Perspective -- Introduction to Pharmacology of Macrophages from Drug Delivery Perspective -- Mechanisms and Ways of Macrophage Delivery -- Macrophage Associated Disorders: Pathophysiology, Treatment Challenges and Possible Solutions -- Understanding Macrophage Associated Diseases and Applications of Nano Drug Delivery Systems -- Part II Polymeric Nanoparticles for Macrophage Targeting -- Targeting of Macrophages: Basic and therapeutic Role of Polymeric Nanoparticles -- Polymeric Nanoparticles Based Drug and Gene Delivery to Macrophages -- Surface Modification of Nanoparticles for Macrophage Targeting -- Part III Lipid Nanoparticles for Macrophage Targeting -- Liposomes as Delivery System for Macrophage Targeting -- Solid Lipid Nanoparticles Based Drug and Gene Delivery to Macrophages -- In vivo Fate of Colloidal Carriers Undergoing Macrophage Targeting -- Nanoparticle-based Theranostics for Macrophage-associated Diseases -- Part IV Targeting Macrophages for Treatment of Various Diseases -- Tumor Associated Macrophages as Therapeutic Target for Drug/immune Therapy of Cancer -- Macrophage Targeting for Therapy of Autoimmune Diseases -- Macrophage Targeting for Therapy of Cardiovascular Diseases (CVD) -- Macrophage targeting for therapy of intracellular infections -- Targeting Drugs and Nucleic Acids to Macrophages for Therapy of Inflammatory Diseases -- Macrophage Targeted Chemotherapy for Tuberculosis and other Respiratory Disease. -- Part V Specific Formulations and Clinical Trials on Macrophage Targeted Delivery -- Nano- and Microparticles Based Dry Powder Inhalers for Pulmonary Macrophage Drug Delivery -- Recent Trends in Clinical Studies on Macrophage Targeted Delivery -- Future Directions and Challenges in Macrophage Targeting. .
    Kurzfassung: The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting. Macrophages have gained substantial attention as therapeutic targets for drug delivery considering their major role in health and regulation of diseases. Macrophage-targeted therapeutics have now added significant value to the lives and quality of life of patients, without undue adverse effects in multiple disease settings. We anticipate examining and integrating the role of macrophages in the instigation and advancement of various diseases. The major focus of the book is on recent advancements in various targeting strategies using delivery systems or nanocarriers followed by application of these nanocarriers for the treatment of macrophage associated disorders. Macrophage Targeted Delivery Systems is primarily targeted to Pharmaceutical Industry & Academia, Medical & Pharmaceutical Professionals, Undergraduate & Post graduate students and Research Scholars, Ph.D, post docs working in the field of medical and pharmaceutical sciences.
    Materialart: Online-Ressource
    Seiten: XVIII, 556 p. 76 illus., 73 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030841645
    URL: https://doi.org/10.1007/978-3-030-84164-5
    DOI: 10.1007/978-3-030-84164-5
    DDC: 615
    Sprache: Englisch
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  • 22
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    Online-Ressource
    Managing Landscapes for Change (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Human geography. ; Environmental management. ; Agriculture. ; Physical geography. ; Energy policy. ; Energy and state. ; Human Geography. ; Environmental Management. ; Agriculture. ; Physical Geography. ; Energy Policy, Economics and Management.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. What is a Landscape? -- Chapter 3. Drivers of Landscape Change -- Chapter 4. Landscape Trajectories -- Chapter 5. Options for Managing Landscape for Change -- Chapter 6. Barriers to Managing for Change -- Chapter 7. Social and Institutional Innovations -- Chapter 8. Technologies for Innovating Forward -- Chapter 9. Conclusions and Recommendation.
    Kurzfassung: This book discusses how future landscapes will be shaped by pervasive change and where, when, and how society should manage landscapes for change. Readers will learn about the major anthropogenic drivers of landscape change, including climate change and human induced disturbance regimes, and the unique consequences that multiple and simultaneously occurring change agents can have on landscapes. The author uses landscape trajectories as a guide to selecting the appropriate course of action, and considers how landscape position, inertia, and direction will determine landscape futures. The author introduces the concept of landscapes as socio-technical-ecological systems (STES), which combines ecological and technological influences on future landscape change and the need for society to acknowledge both when considering landscape management. Thinking beyond solutions, the author identifies barriers to managing landscapes for change including the cost, cultural identity of local populations, and the fear of taking action under uncertain conditions. Nevertheless, processes, tools, and technologies exist for overcoming social and ecological barriers to managing landscapes for change, and continued investment in social and scientific infrastructure holds out hope for maintaining our landscape values even as we enter an era of unprecedented change and disruption.
    Materialart: Online-Ressource
    Seiten: XI, 111 p. 36 illus., 25 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030620417
    Serie: Landscape Series, 27
    URL: https://doi.org/10.1007/978-3-030-62041-7
    DOI: 10.1007/978-3-030-62041-7
    DDC: 304.2
    Sprache: Englisch
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  • 23
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    Online-Ressource
    Synbiotics for the Management of Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Beschreibung / Inhaltsverzeichnis: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Kurzfassung: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Materialart: Online-Ressource
    Seiten: XVII, 340 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811975509
    URL: https://doi.org/10.1007/978-981-19-7550-9
    DOI: 10.1007/978-981-19-7550-9
    DDC: 615
    Sprache: Englisch
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  • 24
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    Online-Ressource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Beschreibung / Inhaltsverzeichnis: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Kurzfassung: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Materialart: Online-Ressource
    Seiten: XXI, 770 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
    Sprache: Englisch
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  • 25
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    Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Beschreibung / Inhaltsverzeichnis: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Kurzfassung: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Materialart: Online-Ressource
    Seiten: XVII, 429 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819969173
    URL: https://doi.org/10.1007/978-981-99-6917-3
    DOI: 10.1007/978-981-99-6917-3
    DDC: 615
    Sprache: Englisch
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  • 26
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    Online-Ressource
    Pharmacology of Immunotherapeutic Drugs (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Immunology. ; Pharmacology. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: Preface Chapter 1: Overview of the Immune System and its Pharmacological Targets -- Chapter 2: Modulation of the Innate Immune System -- Chapter 3: Modulation of the Adaptive Immune System -- Chapter 4: Respiratory Disorders of the Immune System and their Pharmacological Treatment -- Chapter 5: Inflammation of the Skin and its therapeutic topics -- Chapter 6: Inflammatory Diseases of the Gastrointestinal Tract and Pharmacological Treatments -- Chapter 7: Mechanisms of Autoimmunity and Pharmacologic Treatments -- Chapter 8: Transplantation: Immunologic Principles and Pharmacologic Agents -- Chapter 9: Immunopathogenesis, Immunization, and Treatment of Infectious Diseases -- Chapter 10: Cancer Immunotherapy.
    Kurzfassung: Medicine has entered a golden age in which therapeutic agents are becoming widely available due to advances in basic science and technology. As such, many drugs have been developed that target inflammatory processes and/or the immune system. This book is intended for health professionals examining the modulation of inflammation by immunotherapeutic drugs. The immune system fills the primordial role of host defense and resistance to infections with pathogenic microorganisms. Several hematopoietic-derived cells constituting the innate and adaptive immune systems cooperate to provide barriers for microbial colonization and/or promote pathogen destruction within the host. Conversely, many immune cells are also involved in the pathogenesis and propagation of chronic inflammatory diseases. The beginning of this book details various components of the immune system including the cell types, lymphoid tissues, soluble cytokines and surface molecules that are essential for host defense. Breakdowns in immune tolerance, or dysregulated immune responses to antigens derived from self tissues or innocuous sources, can lead to the development of autoimmunity or chronic inflammatory diseases. Pathophysiologic roles for the immune system are detailed in corresponding chapters on autoimmunity, epithelial surfaces (lungs, skin, intestine), and transplantation, with special emphasis placed on immunotherapeutic drug targets. The last section of the book focuses on treatments that stimulate our immune system to specifically target and fight infectious diseases and cancer. In each chapter, the medications used to treat various diseases/conditions in terms of their mechanism of action and other pharmacologic properties are discussed in detail. Chapters begin with a table showing drug names and classifications. The importance of basic science and clinical trials cannot be understated in the context of drug development. As such, the discovery of certain medications that had a lasting impact in medicine and pharmacy are highlighted in chapter subsections named “Bench to Bedside.” Several clinical applications of immunotherapeutic drugs are described within end-of -chapter case studies including practice questions. The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
    Materialart: Online-Ressource
    Seiten: XIX, 399 p. 118 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030199227
    URL: https://doi.org/10.1007/978-3-030-19922-7
    DOI: 10.1007/978-3-030-19922-7
    DDC: 615
    Sprache: Englisch
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  • 27
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    Online-Ressource
    Biomedical Applications and Toxicity of Nanomaterials (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Kurzfassung: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Materialart: Online-Ressource
    Seiten: XVIII, 768 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811978340
    URL: https://doi.org/10.1007/978-981-19-7834-0
    DOI: 10.1007/978-981-19-7834-0
    DDC: 615
    Sprache: Englisch
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  • 28
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    Online-Ressource
    Pharmacology of Drug Stereoisomers (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Medicinal chemistry. ; Pharmaceutical chemistry. ; Biotechnology. ; Biochemical engineering. ; Pharmacology. ; Medicinal Chemistry. ; Pharmaceutics. ; Biotechnology. ; Bioprocess Engineering.
    Beschreibung / Inhaltsverzeichnis: Preface -- General principles of chirality -- Quantitative methods of analysing chirality drugs - Chirality and pharmacokinetics -- Drugs regulating the function of peripheral nervous system -- In silico search for chiral drug compounds.
    Kurzfassung: The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.
    Materialart: Online-Ressource
    Seiten: XI, 207 p. 174 illus., 6 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811923203
    Serie: Progress in Drug Research, 76
    URL: https://doi.org/10.1007/978-981-19-2320-3
    DOI: 10.1007/978-981-19-2320-3
    DDC: 615
    Sprache: Englisch
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  • 29
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    Online-Ressource
    Rabies and Rabies Vaccines (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: Rabies Life Cycle, Transmission and Pathogenesis -- History of Rabies and Rabies Vaccines -- Rabies vaccines for wildlife -- Human Rabies Vaccines -- Rabies vaccines, prophylactic, Peru -- Rabies Prevention in Asia: Institutionalizing Implementation Capacities -- Passive Immunity in Rabies Prophylaxis -- Rabies Little Virus Against Powerful Innate Immunity -- Novel Rabies Vaccines -- Assessing the potency of inactivated veterinary vaccines and oral live vaccines against rabies -- WHO Perspective on Rabies.
    Kurzfassung: This book reviews the recent advances in rabies research and rabies vaccine development. The reader is introduced to biology and pathology of the virus, causing agents and the history of rabies vaccination. The book presents regional rabies prophylaxis programs and discusses vaccination strategies for wildlife and humans. Further, innate immune response as well as antibody response to rabies are examined. All chapters are written by renowned experts in rabies research, some of them part of the WHO Collaboration Centre for Rabies Surveillance and Research. The book targets researchers and health professionals working in Virology, Veterinary Medicine and Biomedicine. .
    Materialart: Online-Ressource
    Seiten: VII, 205 p. 15 illus., 12 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030210847
    URL: https://doi.org/10.1007/978-3-030-21084-7
    DOI: 10.1007/978-3-030-21084-7
    DDC: 615
    Sprache: Englisch
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  • 30
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    Online-Ressource
    Principles of Forensic Toxicology (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Forensic sciences. ; Medical jurisprudence. ; Pharmacology. ; Forensic Science. ; Forensic Medicine.
    Beschreibung / Inhaltsverzeichnis: Part 1: Introduction -- Post Mortem Forensic Toxicology -- Human Performance Toxicology -- Drug-Facilitated Sexual Assault -- Forensic Drug Testing -- Performance enhancing Drug Testing -- Drug Testing in Pain Management -- Pharmacokinetics and Pharmacodynamics -- Part II. Specimen Preparation -- Spectrophotometry -- Chromatography -- Derivatization -- Immunoassy -- Mass Spectrometry -- Quantitation -- Method Validation -- Measurement Uncertainty and Traceability -- Statistics in Forensic Toxicology -- Part III Analytes -- Alcohol -- Benzodiazapines -- Gammahydroxybutyric acid,- Miscellaneous Central Nervous System Depressants -- Opioids -- Cocanie -- Cannabis -- Amphetamines-Sympathomimetic Amines,- Hallucinogens and Psychedelics -- Antidepressants and Neuroleptics -- Miscellaneous Therapeutic Drugs -- Carbon Monoxide/Cyanide -- Inhalants -- Metals -- Part III Special Topics -- Stability of Drugs of Abuse in Biological Systems -- Postmortem Redistribution of Drugs -- Postmortem Clinical Testing -- Pharmacogenomics -- Hair Drug Testing -- Oral Fluid Testing -- Meconium Drug Testing -- Drugs in Embalmed Tissues.
    Kurzfassung: The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.
    Materialart: Online-Ressource
    Seiten: XIII, 691 p. 188 illus., 23 illus. in color. , online resource.
    Ausgabe: 5th ed. 2020.
    ISBN: 9783030429171
    URL: https://doi.org/10.1007/978-3-030-42917-1
    DOI: 10.1007/978-3-030-42917-1
    DDC: 615
    Sprache: Englisch
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    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Beschreibung / Inhaltsverzeichnis: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Kurzfassung: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Materialart: Online-Ressource
    Seiten: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
    Sprache: Englisch
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  • 32
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    Online-Ressource
    From PharmD to Industry : A Fellowship Guide (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Beschreibung / Inhaltsverzeichnis: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Kurzfassung: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Materialart: Online-Ressource
    Seiten: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031357879
    Serie: SpringerBriefs in Pharmaceutical Science & Drug Development,
    URL: https://doi.org/10.1007/978-3-031-35787-9
    DOI: 10.1007/978-3-031-35787-9
    DDC: 615
    Sprache: Englisch
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  • 33
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    Online-Ressource
    Contract Research and Development Organizations-Their History, Selection, and Utilization (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Pharmacy. ; Pharmacology. ; Pharmacy.
    Beschreibung / Inhaltsverzeichnis: Introduction -- History of CROs: Including CRO Snapshots and a CRO Genealogy Chart -- The Pharmaceutical Development Process & Testing Requirements -- The Medical Device Development Process & Testing Requirements -- Functions and Types of CROs -- Labs in China and India -- Selection of CROs -- Study Directors and PIs -- Nuts and Bolts of Study Performance SCG/CBS -- Electronic Reporting Requirements (SEND & eCTD) -- Study and Project Monitoring -- Contracting, Pricing, and Cost of Works Performed by CROs -- Consultants and their Role -- Building Relationships: Maximizing your return on Expectations with a CRO -- Common Problems and their Solutions -- Appendices: A Toxicology Labs B Medical Device Labs C Phase I Labs D Analytical Labs E GMP Contract Facilities F Formulation G Dosage Forms H Clinical Testing I Regulatory Services J Forms and Checklists -- K Specialized Services -- L Consultants Known to be In-Practice -- Index. .
    Kurzfassung: This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: · The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. · Study directors and principal investigators. · The nuts and bolts of study performance. · Electronic reporting requirements – SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). · Consultants and their roles. · An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs – where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities – and for auditing studies and projects at such facilities – are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.
    Materialart: Online-Ressource
    Seiten: XIII, 519 p. 19 illus., 1 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030430733
    URL: https://doi.org/10.1007/978-3-030-43073-3
    DOI: 10.1007/978-3-030-43073-3
    DDC: 615
    Sprache: Englisch
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  • 34
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    Online-Ressource
    Toll-like Receptors in Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Immunology. ; Inflammation. ; Pharmacology. ; Immunology. ; Inflammation.
    Beschreibung / Inhaltsverzeichnis: Intracellular TLRs (TLR3, TLR7, and TRL9) in host defense or TLRs in mast cells -- Toll-like receptors as drug targets in the intestinal epithelium -- Innate immune memory-priming, tolerance and exhaustion-in health and disease -- TLRs in brain immunity -- TLRs in cerebrovascular diseases -- TLRs in stem cells or progenitor cells -- TLRs in adaptive immunity -- Overview on TLRs in immunity -- TLR10 and its role in immunity.
    Kurzfassung: The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolutionized the field of innate immunity and filled the long-standing gap in the pathogen recognition by the immune system. Now, it is well established that humans have 10 (TLR1-TLR10) and mice have 12 (TLR1-TLR13) functional TLRs, excluding TLR10 that is present as a defective pseudogene. TLRs are present as both membrane-bound extracellular (TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10) and intracellular (TLR3, TLR7, TLR8, and TLR9) PRRs in humans, which identify different pathogen or microbe-associated molecular patterns (PAMPs or MAMPs) and death or damage-associated molecular patterns (DAMPs) released by the host cells. A lot of development in the TLR biology has occurred in last 24 years since there first discovery in humans. The book is intended to describe their role in the host defence, human reproduction, non-infectious sterile inflammatory conditions, including brain immunity and cerebrovascular diseases, signaling mechanisms, adaptive immunity, and their targeting for drug development.
    Materialart: Online-Ressource
    Seiten: VIII, 314 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031065125
    Serie: Handbook of Experimental Pharmacology, 276
    URL: https://doi.org/10.1007/978-3-031-06512-5
    DOI: 10.1007/978-3-031-06512-5
    DDC: 615
    Sprache: Englisch
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  • 35
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    Online-Ressource
    Prebiotics, Probiotics and Nutraceuticals (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Kurzfassung: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Materialart: Online-Ressource
    Seiten: XVI, 340 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811689901
    URL: https://doi.org/10.1007/978-981-16-8990-1
    DOI: 10.1007/978-981-16-8990-1
    DDC: 615
    Sprache: Englisch
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  • 36
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    Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Surgery. ; Dentistry. ; Veterinary medicine. ; Neurology . ; Orthopedic surgery. ; Pharmacology. ; Surgery. ; Dentistry. ; Veterinary Science. ; Neurology. ; Surgical Orthopedics.
    Beschreibung / Inhaltsverzeichnis: 1. History of development of botulinum toxin therapy in medical and surgical fields -- 2. Molecular structure and mechanisms of action of botulinum toxins as it pertains to clinical symptoms -- 3. Types of toxins in commercial use, their similarities and differences -- 4. A review of current Botulinum toxin treatment indications in medical field. - 5. Mechanisms of Analgesic effects of botulinum neurotoxins -- 6. Botulinum toxin treatment in Head and neck surgery -- 7. Botulinum toxin treatment of thoracic and abdominal surgery -- 8. Botulinum Toxin A in Abdominal Wall Reconstruction -- 9. Use of Botulinum toxin A in post-mastectomy breast reconstruction -- 10. Botulinum Toxins for Treatment of Pain in Orthopedic Disorders -- 11. Botulinum toxin for pediatric patients, Who? For what? When? -- 12. Botulinum Toxin Treatment in Plastic Surgery -- 13. Botulinum Toxin Treatment in Ophthalmology and Ophthalmic surgery -- 14. Botulinum Toxin Treatment in Gastrointestinal Disorders -- 15. Botulinum Toxin Treatment in Urological Disorders -- 16. Botulinum Toxin Treatment in Dentistry -- 17. Botulinum toxin treatment in Veterinary Medicine - Clinical implications -- 18. Future Perspectives of Botulinum Toxin Application In Dentistry.
    Kurzfassung: All books on the market which have been written on the subject of botulinum toxin therapy focus on treatment of hyperactive movement disorders, autonomic dysfunction (bladder, sweat and salivary glands) and some pain indications (migraine). Reference to pre-or post -surgical indications are brief and often out-dated. No book has information on dentistry or veterinary medicine. This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine and furnishes the latest information. Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine appeals to many disciplines including surgery, dentistry and veterinary medicines well as appealing to neurologists and internists.
    Materialart: Online-Ressource
    Seiten: VIII, 398 p. 70 illus., 60 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030506919
    URL: https://doi.org/10.1007/978-3-030-50691-9
    DOI: 10.1007/978-3-030-50691-9
    DDC: 615
    Sprache: Englisch
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  • 37
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    Online-Ressource
    Metabolomics and Its Impact on Health and Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Biochemical markers. ; Cytology. ; Analytical biochemistry. ; Pharmacology. ; Biomarkers. ; Cell Biology. ; Analytical Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
    Kurzfassung: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
    Materialart: Online-Ressource
    Seiten: VIII, 384 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031268595
    Serie: Handbook of Experimental Pharmacology, 277
    URL: https://doi.org/10.1007/978-3-031-26859-5
    DOI: 10.1007/978-3-031-26859-5
    DDC: 615
    Sprache: Englisch
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  • 38
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    Online-Ressource
    Structure and Health Effects of Natural Products on Diabetes Mellitus (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Botanical chemistry. ; Bioorganic chemistry. ; Pharmacology. ; Plant Biochemistry. ; Bioorganic Chemistry.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction of diabetes melitus and future prospects of natural products on diabetes melitus -- Chapter 2. Anoverview of hypoglycemic modern drugs -- Chapter 3. An overview of hypoglycemic biological drugs -- Chapter 4. An overview of hypoglycemic traditionaldrugs -- Chapter 5. Glycosides from natural sources in the treatment of diabetes mellitus -- Chapter 6. Isolation and Structure Elucidation of Hypoglycemic Compounds -- Chapter 7. Structural Characterization and Health Effects of Polysaccharides from Momordica charantia on Diabetes Mellitus -- Chapter 8. Effects of polysaccharides on reducing blood glucose based on gut microbiota alteration -- Chapter 9. An Overview of Polysaccharides and the influencefactors of Hypoglycemic Activity -- Chapter 10. Plant Secondary Metabolites with α-Glucosidase Inhibitory Activity. - Chapter 11. Rhinacanthin-C and Its Potential to Control Diabetes Mellitus -- Chapter 12. Regeneration of beta cells by inhibition of pro-apoptotic proteins through phytocompound in STZ induced diabetic albino wistar rats-invivo and insilico approach. - Chapter 13. Nitrogenous Compounds from Plant Origin in Management of -- Chapter 14. Plant Alkaloids with Antidiabetic Potential -- Chapter 15. The role of Alkaloids in the Management of Diabetes Mellitus -- Chapter 16. Traditional Indian Herbs for the Management of Diabetes Mellitus and their Herb-Drug Interaction Potentials: An Evidence-Based Review -- Chapter 17. Role of Micronutrients and Trace elements in Diabetes mellitus: A Review.
    Kurzfassung: The purpose of this book is to introduce the classified chemical components of hypoglycemic compounds in natural products, summarize the recent research progress of natural products with hypoglycemic activity in the past 20 years, and provide the original analysis and development opinions of relevant scholars. Hypoglycemic compounds are to target diabetes mellitus, an important public health problem, one of four priority noncommunicable diseases (NCDs) targeted for action by world leaders. Diabetes mellitus is a common endocrine and metabolic disease, which not only causes physiological damage to patients' kidneys, cardiovascular and cerebrovascular vessels, peripheral blood vessels, nerves and eyes, but also causes mental and psychological pressure to patients. Due to the evidence that traditional medicine and natural herbal formula have advantages in treating diabetes, natural products with hypoglycemic activity have been studied extensively in recent years and have been accepted by many scholars all over the world. This book focuses on the progress on the study of the structure, hypoglycemic activities, structure-activity relationships and mechanism of a wide range of polysaccharides, flavonoids, saponins, alkaloids, terpenoids, polyphenols and other constituents. It will help students and researchers to understand current approaches and progress in the treatment of diabetes with natural products, which may also be beneficial to develop new hypoglycemic drugs.
    Materialart: Online-Ressource
    Seiten: VIII, 307 p. 85 illus., 16 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811587917
    URL: https://doi.org/10.1007/978-981-15-8791-7
    DOI: 10.1007/978-981-15-8791-7
    DDC: 615
    Sprache: Englisch
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  • 39
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    Online-Ressource
    Pharmacology of Immunosuppression (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Human physiology. ; Immunology. ; Surgery. ; Pharmacology. ; Human Physiology. ; Immunology. ; Surgery.
    Beschreibung / Inhaltsverzeichnis: Review of the Pathophysiology of the Alloimmune response -- A Comprehensive Review of Calcineurin Inhibitors Used for Immunosuppression in Cardiac Transplantation -- Anti-proliferative Agents -- Mechanistic Target of Rapamycin (mTOR) Inhibitors -- Corticosteroids -- Induction therapy and antibodies -- Immunosuppression and Heart Transplantation -- Immunosuppression and Lung Transplantation -- Immunosuppression and renal transplant recipients -- Immunosuppression in Rheumatologic and Auto-immune Disease -- Immunosuppression in Bone Marrow Transplantation -- Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders -- Novel immunosuppressive agents for the treatment of organ transplants -- Adverse Effects of Immunosuppression: Infections -- Malignancy: An Adverse Effect of Immunosuppression -- Adverse Effects of Immunosuppression:Nephrotoxicity, Hypertension and Metabolic Disease.
    Kurzfassung: The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bone marrow transplantation and autoimmune diseases and inflammatory diseases. This book is a critical review of these topics and a vital resource.
    Materialart: Online-Ressource
    Seiten: VIII, 348 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031051180
    Serie: Handbook of Experimental Pharmacology, 272
    URL: https://doi.org/10.1007/978-3-031-05118-0
    DOI: 10.1007/978-3-031-05118-0
    DDC: 615
    Sprache: Englisch
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  • 40
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    Online-Ressource
    Evidence Based Validation of Traditional Medicines : A comprehensive Approach (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Kurzfassung: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Materialart: Online-Ressource
    Seiten: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811581274
    URL: https://doi.org/10.1007/978-981-15-8127-4
    DOI: 10.1007/978-981-15-8127-4
    DDC: 615
    Sprache: Englisch
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  • 41
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    From Obesity to Diabetes (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Pharmacology. ; Metabolism Disorders. ; Pharmacology. ; Metabolic Disease.
    Beschreibung / Inhaltsverzeichnis: Part I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
    Kurzfassung: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
    Materialart: Online-Ressource
    Seiten: VIII, 513 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030999957
    Serie: Handbook of Experimental Pharmacology, 274
    URL: https://doi.org/10.1007/978-3-030-99995-7
    DOI: 10.1007/978-3-030-99995-7
    DDC: 615
    Sprache: Englisch
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  • 42
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    Online-Ressource
    Immunity Boosting Medicinal Plants of the Western Himalayas (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Kurzfassung: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Materialart: Online-Ressource
    Seiten: XIX, 609 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811995019
    URL: https://doi.org/10.1007/978-981-19-9501-9
    DOI: 10.1007/978-981-19-9501-9
    DDC: 615
    Sprache: Englisch
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  • 43
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    Online-Ressource
    Nanoformulations in Human Health : Challenges and Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Therapeutics. ; Pharmacology. ; Therapeutics.
    Beschreibung / Inhaltsverzeichnis: Nano-technological Platforms and Manipulations for the Emerging Ocular Manifestations -- Phytonanomedicines as Topical Alternatives for the Treatment of Skin Cancer -- Nano-sized Labile and Particulate Ingredients in Topical Formulations: A Strategic Approach Against Photoageing and Photocarcinogenisis -- Application of Biocompatible Nanocarriers in Glaucoma: Challenges and Advances -- Nano-carriers for Natural Therapeutics in the Management of Neuropathic Pain -- Advances in the Delivery of Therapeutic Peptides -- Nanoformulations and Their Role in Colon Targeting -- Theranostic Nanoformulations: Merging Diagnostics and Therapeutics -- The Role of Nanoformulations in Nose-To-Brain Drug Delivery -- Cubic Lyotropic Liquid Crystalline Nanostructures: A Versatile Platform for Delivery -- Preformulation Challenges: The Concept Behind the Selection, Design, and Preparation of Nanoformulations -- Nanoethosomes for Topical Fungal Therapeutics -- Comparison of Therapeutic Efficiency of Nanoformulations of Curcumin vs. Tetrahydrocurcumin in Various Disorders -- Nanomedicinal Approaches of Phytotherapeutics to Treat Alzheimers Disease -- Nanoparticulate Approaches to Exploit the Pathophysiology of Rheumatoid and Osteoarthritis -- Emerging Nanotechnology in Chronic Respiratory Diseases -- Conventional and Non-conventional Approaches of Site-specific Targeting of Therapeutics in Some Infectious Diseases and Metabolic Disorders -- Nanoformulations in Human Health Conditions: The Paradigm Shift -- Magnetic Nanoparticles Nanoformulation for Alternative Therapy of Cancer by Super-paramagnetic Hyperthermia -- Nano-weapons Against Tuberculosis -- Drug-Excipient Interactions in Nanoformulations with Special Focus on Impurity Control per ICH guidelines.
    Kurzfassung: This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
    Materialart: Online-Ressource
    Seiten: XVIII, 548 p. 106 illus., 91 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030418588
    URL: https://doi.org/10.1007/978-3-030-41858-8
    DOI: 10.1007/978-3-030-41858-8
    DDC: 615
    Sprache: Englisch
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  • 44
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    Online-Ressource
    Emerging Technologies for Nanoparticle Manufacturing (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Nanotechnology. ; Nanochemistry. ; Pharmacology. ; Nanotechnology. ; Nanochemistry.
    Beschreibung / Inhaltsverzeichnis: Part 1 Introduction and Biomedical Applications of Nanoparticles -- 1. Introduction to Nanomaterials and Nanotechnology -- 2. Biomedical Applications of Nanoparticles -- Part II-Polymeric Nanoparticles -- 3. Nanocrystallization and Nanoprecipitation Technologies -- 4. Microfluidics Technology for Nanoparticles and Equipment-. 5. Production of Nanocomposites via Extrusion Techniques -- 6. The Use of Supercritical Fluids Technologies for Nanoparticle Production -- 7. Salting out and Ionic Gelation Manufacturing Techniques for Nanoparticles -- 8. Nanogel Synthesis by Irradiation of Aqueous Polymer Solutions -- 9. Cellulose acetate based nanofibers: Synthesis, Manufacturing and Applications -- 10. Production of nanofibers, environmental challenges and solutions -- Part III-Lipid Nanoparticles -- 11. High Pressure Homogenization Techniques for Nanoparticles -- 12. Solvent emulsification evaporation and solvent emulsification diffusion techniques for nanoparticles -- 13. Ultrasound Activated Nanoemulsions -- 14. Multiple Emulsions: Emphasizing on industrial applications -- 15. Membrane techniques for the preparation of nanomaterials -- 16. Self-assembling Lipid Nanoparticles/Nanosystems (SLNN) using Hydrophilic Solvents: Overview and Industrial Uses -- 17. Nanoemulsions – An emerging technology in drug delivery -- Part IV- Metallic Nanoparticles -- 18. Manufacturing techniques for carbon nanotubes, gold nanoparticles and silver nanoparticles -- 19. Radio frequency (RF) plasma-based Synthesis of metallic Nano particles for Biomedical Application -- 20. Techniques for accurate sizing of nanoparticles -- 21. Silver nanoparticles synthesis from cyanobacteria: Environmental and biomedical applications -- 22. Selenium Nanoparticles: Green Synthesis and Exploitation -- Part V- Quality control for nanoparticles -- 23. Practical guidelines for the characterization and quality control of nanoparticlesin the pharmaceutical industry -- Part VI-Challenges in scale-up production of nanoparticles -- 24. Nanomedicine Scale-Up Technologies: Feasibilities and Challenges -- 25. Patent survey on recent technology for nanoparticles -- Part VII-Injectable Nanosystems -- 26. Injectable Nanosystems and Inherent Nano-Serum Interactions -- Part VIII- Future directions and challenges -- 27. Current Challenges and Future Directions in Nanomedicine.
    Kurzfassung: This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of Nanoparticles II. Polymeric Nanoparticles III. Lipid Nanoparticles IV. Metallic Nanoparticles V. Quality Control for Nanoparticles VI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and Challenges Leading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges. .
    Materialart: Online-Ressource
    Seiten: XV, 611 p. 155 illus., 117 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030507039
    URL: https://doi.org/10.1007/978-3-030-50703-9
    DOI: 10.1007/978-3-030-50703-9
    DDC: 615
    Sprache: Englisch
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  • 45
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    Online-Ressource
    Antiviral Drug Discovery and Development (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Pharmacy. ; Biotechnology. ; Pharmacology. ; Pharmacy. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: 1 Antiviral Drugs Against Herpesviruses -- 2 An Update on Antiretroviral Therapy -- 3 Structural Insights to Human Immunodeficiency Virus (HIV-1) Targets and their Inhibition -- 4 LEDGINs, Inhibitors of the Interaction between HIV-1 Integrase and LEDGF/p75, are Potent Antivirals with a Potential to Cure HIV Infection -- 5 Moving Fast Towards Hepatitis B Virus Elimination -- 6 Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection -- 7 Phytoconstituents as Lead Compounds for Anti-dengue Drug Discovery -- 8 Anti-influenza Drug Discovery and Development: Targeting the Virus and its Host by all -- 9 Search, Identification and Design of Effective Antiviral Drugs against Pandemic Human Coronaviruses -- 10 Peptide Based Antiviral Drugs -- 11 Covalent Antiviral Agents -- 12 Safe-in-Man Broad Spectrum Antiviral Agents -- 13 Exploiting Ubiquitin ligases for Induced Target Degradation as an Antiviral Strategy. .
    Kurzfassung: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.
    Materialart: Online-Ressource
    Seiten: XI, 357 p. 142 illus., 64 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811602672
    Serie: Advances in Experimental Medicine and Biology, 1322
    URL: https://doi.org/10.1007/978-981-16-0267-2
    DOI: 10.1007/978-981-16-0267-2
    DDC: 615
    Sprache: Englisch
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  • 46
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    Online-Ressource
    Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Medical genetics. ; Human physiology. ; Pharmacology. ; Medical Genetics. ; Human Physiology.
    Beschreibung / Inhaltsverzeichnis: Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.
    Kurzfassung: The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
    Materialart: Online-Ressource
    Seiten: XII, 316 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031384370
    Serie: Handbook of Experimental Pharmacology, 279
    URL: https://doi.org/10.1007/978-3-031-38437-0
    DOI: 10.1007/978-3-031-38437-0
    DDC: 615
    Sprache: Englisch
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  • 47
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    Online-Ressource
    Edible Plants in Health and Diseases : Volume II : Phytochemical and Pharmacological Properties (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Beschreibung / Inhaltsverzeichnis: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Kurzfassung: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Materialart: Online-Ressource
    Seiten: IX, 522 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811649592
    URL: https://doi.org/10.1007/978-981-16-4959-2
    DOI: 10.1007/978-981-16-4959-2
    DDC: 615
    Sprache: Englisch
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  • 48
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    Online-Ressource
    The Kappa Opioid Receptor (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Pharmacology.
    Beschreibung / Inhaltsverzeichnis: From the contents. Preface.-Part I: Molecular aspects of KOR -- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals -- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.
    Kurzfassung: This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Materialart: Online-Ressource
    Seiten: XI, 577 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030890742
    Serie: Handbook of Experimental Pharmacology, 271
    URL: https://doi.org/10.1007/978-3-030-89074-2
    DOI: 10.1007/978-3-030-89074-2
    DDC: 615
    Sprache: Englisch
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  • 49
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    Behavioral Neurobiology of GABAB Receptor Function (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Kurzfassung: It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.
    Materialart: Online-Ressource
    Seiten: VII, 329 p. 70 illus., 15 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030913359
    Serie: Current Topics in Behavioral Neurosciences, 52
    URL: https://doi.org/10.1007/978-3-030-91335-9
    DOI: 10.1007/978-3-030-91335-9
    DDC: 615
    Sprache: Englisch
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  • 50
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    Online-Ressource
    Marine Biomaterials : Drug Delivery and Therapeutic Applications (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Kurzfassung: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Materialart: Online-Ressource
    Seiten: X, 453 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811647871
    URL: https://doi.org/10.1007/978-981-16-4787-1
    DOI: 10.1007/978-981-16-4787-1
    DDC: 615
    Sprache: Englisch
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  • 51
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    Online-Ressource
    Parkinsonism and the Environment (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Neurosciences. ; Pharmacology. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Experimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson’s Disease: current state of affairs?” -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism.
    Kurzfassung: “The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”.
    Materialart: Online-Ressource
    Seiten: V, 158 p. 14 illus., 8 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030874513
    Serie: Molecular and Integrative Toxicology,
    URL: https://doi.org/10.1007/978-3-030-87451-3
    DOI: 10.1007/978-3-030-87451-3
    DDC: 615
    Sprache: Englisch
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  • 52
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    Ethnopharmacology and Drug Discovery for COVID-19: Anti-SARS-CoV-2 Agents from Herbal Medicines and Natural Products (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Beschreibung / Inhaltsverzeichnis: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Kurzfassung: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Materialart: Online-Ressource
    Seiten: IX, 590 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819936649
    URL: https://doi.org/10.1007/978-981-99-3664-9
    DOI: 10.1007/978-981-99-3664-9
    DDC: 615
    Sprache: Englisch
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  • 53
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    Online-Ressource
    Novel Drug Targets With Traditional Herbal Medicines : Scientific and Clinical Evidence (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Natural products. ; Pharmacology. ; Toxicology. ; Pharmaceutics. ; Medicinal Chemistry. ; Natural Products.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Achillea biebersteinii Afan -- Chapter 2: Aesculus hippocastanum L. -- Chapter 3: Berberis crataegina DC. -- Chapter 4: Calendula officinalis L. -- Chapter 5: Camellia sinensis (L.) Kuntze -- Chapter 6: Capsella bursa-pastoris (L.) Medik. -- Chapter 7: Capsicum annuum L. -- Chapter 8: Cedrus libani A.Rich. -- Chapter 9: Chelidonium majus L. -- Chapter 10: Cichorium intybus L. -- Chapter 11: Cistus laurifolius L. -- Chapter 12: Coriandrum sativum L. -- Chapter 13: Cornus mas L. -- Chapter 14: Curcuma longa L..-Chapter 15: Cydonia oblonga Mill. -- Chapter 16: Cynara scolymus L. -- Chapter 17: Equisetum arvense L. -- Chapter 18: Foeniculum vulgare Mill. -- Chapter 19: Fraxiınus ornus L. -- Chapter 20: Fumaria officinalis L. -- Chapter 21: Helichrysum plicatum DC. -- Chapter 22: Hyoscyamus niger L. -- Chapter 23: Juglans regia L. -- Chapter 24: Laurus nobilis L. -- Chapter 25: Liquidambar orientalis Miller -- Chapter 26: Matricaria chamomilla L. -- Chapter 27: Melissa officinalis L. -- Chapter 28: Momordica charantia L. -- Chapter 29: Nigella sativa L. -- Chapter 30: Olea europaea L. -- Chapter 31: Papaver somniferum L. -- Chapter 32: Rheum ribes L. -- Chapter 33: Rosa canina L. -- Chapter 34: Rosmarinus officinalis L. -- Chapter 35: Silybum marianum L. Gaertn. -- Chapter 36: Urtica dioica L -- Chapter 37: Valeriana officinalis L. -- Chapter 38: Viburnum opulus L.
    Kurzfassung: This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world. It presents the ethnopharmacological records, in vivo and in vitro studies, side effects, chemical compositions and clinical studies of these medicinal plants. Its special focus is on the novel drug targets for disease and their possible mechanisms of action. It covers botanical descriptions the status of the plants, and food or drug interactions including precautions and warnings about the plants and the available market products. It provides an explanation of recorded and known plant administration dosages. Also, the gap between the traditional practice and scientific/clinical evidences in the use of ethnomedicinal plant is acknowledged. It is well known that traditional knowledge of the use of the medicinal plants in therapy is an important resource for the discovery of novel treatment options and drug targets. The main purpose of this book is to draw attention to ethnomedicinal plant species. Data on the therapeutic potentials of these medicinal plants can now be accessed from a single source. It provides an important resource for future research opportunities for harnessing the full potential of these plants.
    Materialart: Online-Ressource
    Seiten: XII, 588 p. 119 illus., 43 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031077531
    URL: https://doi.org/10.1007/978-3-031-07753-1
    DOI: 10.1007/978-3-031-07753-1
    DDC: 615
    Sprache: Englisch
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  • 54
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    Online-Ressource
    Herb-Drug Combinations : A New Complementary Therapeutic Strategy (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Kurzfassung: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Materialart: Online-Ressource
    Seiten: XV, 276 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811951251
    URL: https://doi.org/10.1007/978-981-19-5125-1
    DOI: 10.1007/978-981-19-5125-1
    DDC: 615
    Sprache: Englisch
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  • 55
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    Online-Ressource
    Sex and Gender Effects in Pharmacology (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pharmacology. ; Immunology. ; Neurology . ; Endocrinology. ; Cardiology. ; Pharmacology. ; Immunology. ; Neurology. ; Endocrinology. ; Cardiology.
    Beschreibung / Inhaltsverzeichnis: Part 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer’s disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
    Kurzfassung: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
    Materialart: Online-Ressource
    Seiten: VIII, 288 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031426483
    Serie: Handbook of Experimental Pharmacology, 282
    URL: https://doi.org/10.1007/978-3-031-42648-3
    DOI: 10.1007/978-3-031-42648-3
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 56
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    Online-Ressource
    Sustainable Development in Changing Complex Earth Systems (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Physical geography. ; Computer simulation. ; Environment. ; Sustainability. ; Earth System Sciences. ; Physical Geography. ; Computer Modelling. ; Environmental Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter1. Some remarks on sustainable development -- Chapter2. Structure and operation of systems, models of the global earth system -- Chapter3. The global earth system at the beginning of the 21st century -- Chapter4. Steps towards realising global sustainable development.
    Kurzfassung: This book applies system theory to analyze the operation and structure of the complex earth surface system, including the interactions between society and nature that cause environmental degradation and threats to human populations. The possible ways to harmonize the operation of a global society as a complex system using the United Nation sustainable development goals are investigated, as well as the major efforts currently implemented to achieve this objective and why many are unsuccessful. Readers will learn this material through case studies that assess the essential conditions required to occupy a planet sustainably, and examine the complex interactions between society and nature in the atmosphere, hydrosphere, biosphere, and outer layers of the lithosphere. The book is written for undergraduate students in geography, earth sciences, environmental sciences, and ecology, and will also appeal to environmental agency employees, nature protection representatives, teachers, and researchers. .
    Materialart: Online-Ressource
    Seiten: XVIII, 292 p. 143 illus., 63 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030216450
    Serie: Sustainable Development Goals Series,
    URL: https://doi.org/10.1007/978-3-030-21645-0
    DOI: 10.1007/978-3-030-21645-0
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 57
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    Online-Ressource
    Application of the Water Footprint: Water Stress Analysis and Allocation (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Sustainability. ; Water. ; Freshwater and Marine Ecology. ; Pollution.
    Beschreibung / Inhaltsverzeichnis: Introduction -- PART I: Virtual Water and Water Footprint Accounting -- The Concepts of Virtual Water and Water Footprint -- Water Footprint Accounting Method -- PART II: Evaluation of Water Stresses Based on WFs -- Studies on the Evaluation of Water Footprints at Various Regional Scales -- Principal Water Stress Analysis Indexes and Approaches Based on WFs -- PART III: Study Cases: Water Stress Evaluation Under Multiple Regional Scales -- Study Cases: Water Stresses Evaluation at the Provincial Scale —the Zhejiang Province Case Study -- Study Case: Evaluation of Water Stresses at the River Basin Scale — the Haihe River Basin Case Study -- Case Study: Evaluation of Water Stresses at the City Scale —Dalian -- Comparisons of the Major Indexes on Water Stresses Analysis under Multiple Regional Scales -- PART IV: Water Footprint Accounting Application in Water Management Strategies -- Influencing Factors Analysis of Water Footprint Based on Extended STIRPAT Model -- Optimal Water Utilization and Allocation Strategy based on Water Footprint Accounting -- Conclusions. .
    Kurzfassung: Based on the water footprint (WF) concept, this book reviews WF-based water stress evaluation methods at the city, provincial and river basin levels respectively. In addition, it explores the factors that influence regional water footprint in the spatial sequence via the extended STIRPAT model. Highlighting the utilization of WF accounting in sustainable water management, one of the book’s goals is to establish the optimization model of water allocation in various industrial sectors. Based on WF accounting, which thoroughly considers the water input for production, the relevant intermediate water inputs, and the water amount for wastewater discharge dilutions, the book provides a wealth of insights for scholars and practitioners with an interest in water resources and environmental management. In addition, it exhibits a scientific plan for regional water resource utilization and allocation, helping relieve regional water shortages.
    Materialart: Online-Ressource
    Seiten: XVI, 149 p. 48 illus., 46 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811502347
    URL: https://doi.org/10.1007/978-981-15-0234-7
    DOI: 10.1007/978-981-15-0234-7
    DDC: 304.2
    Sprache: Englisch
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  • 58
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    Online-Ressource
    Temporary Appropriation in Cities : Human Spatialisation in Public Spaces and Community Resilience (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Sociology, Urban. ; Sustainable architecture. ; Sustainability. ; Urban Sociology. ; Sustainable Architecture/Green Buildings.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 General Introduction -- Chapter 2 Understanding the Temporary Appropriation in Relationship to Social Sustainability -- Chapter 3 Between Assemblages and Temporary Appropriation: The Case of Mexico City -- Chapter 4 Temporary Appropriation and Informality -- Chapter 5 Ongoing Appropriation: Invisible Seattle and Red May -- Chapter 6 Temporary Appropriation and Public Space: Assessing the CPTED Principle of Activity Support -- Chapter 7 Temporary Appropriation of Public Spaces: The Influence of Outdoor Comfort -- Chapter 8 Origins of Informality: Examining the Historical and Spatial Roots of Informal Day-Labor Hiring Sites -- Chapter 9 Unsheltered Homelessness and the Right to Metabolism: An Urban Political Ecology of Health and Sustainability -- Chapter 10 Temporary Appropriation in Shanghai and Hong Kong: Two Study Cases Assessing the Resilience of Women Faced With the Lack of Affordable Housing -- Chapter 11 (Temporary) Appropriation (Of Space), Makassar, and Urban Kampung -- Chapter 12 Extending Temporary Appropriation Through Architecture: The Role of Adaptive Reuse in Shaping New Zealand’s Built Environment -- Chapter 13 Using the Street in Mexico City Centre: Temporary Appropriation of Public Space Vs Legislation Governing Street Use -- Chapter 14 Transforming Everyday Public Space: Human Appropriations in Search for Citizenship and Urban Well-Being -- Chapter 15 General Conclusion. .
    Kurzfassung: This book conceptualises and illustrates temporary appropriation as an urban phenomenon, exploring its contributions to citizenship, urban social sustainability and urban health. It explains how some forms of appropriation can be subversive, existing in a grey area between legal and illegal activities in the city. The book explores the complex and the multi-scalar nature of temporary appropriation, and touches on its relationship to issues such as: sustainability and building re-use; culture; inclusivity, including socio-spatial inclusion; streetscape design; homelessness; and regulations controlling the use of public spaces. The book focuses on temporary appropriation as a necessity of adapting human needs in a city, highlighting the flexibility that is needed within urban planning and the further research that should be undertaken in this area. The book utilises case studies of Auckland, Algiers and Mexico City, and other cities with diverse cultural and historical backgrounds, to explore how planning, design and development can occur whilst maintaining community diversity and resilience. Since urban populations are certain to grow further, this is a key topic for understanding urban dynamics, and this book will be of interest to academics and practitioners alike.
    Materialart: Online-Ressource
    Seiten: XXVI, 256 p. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030321208
    URL: https://doi.org/10.1007/978-3-030-32120-8
    DOI: 10.1007/978-3-030-32120-8
    DDC: 304.2
    Sprache: Englisch
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  • 59
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    Online-Ressource
    The County Diagnostic : A Regional Environmental Footprint Framework for the USA (2020)
    Wiesbaden :Springer Fachmedien Wiesbaden :
    Details
    Schlagwort(e): Sustainability. ; Environmental management. ; Human geography. ; Sustainability. ; Environmental Management. ; Human Geography.
    Beschreibung / Inhaltsverzeichnis: Existing Footprinting Methods and the Need for Regional Ecological Planning in the USA -- The Urban Metabolism and Flows of the Anthroposphere -- The Dissipative Ecological Unit (DEU) as Organizing Principle for Metabolic Analysis of Counties -- Calculations and Data Sources for the County Diagnostic Method -- A Case Study Application of the County Diagnostic to the Eastern Temperate Forest Ecoregion -- Comparative Vertical Waveform Diagrams for Cases and Interpretation of Case Study Results.
    Kurzfassung: The county diagnostic method is a spatially explicit, unit specific, component expanded regional environmental footprint framework for the USA designed by Bryce Lawrence to compare the influence of ecoregions on poly‐factorial environmental footprints. This 'diagnostic assessment' quantifies and compares the flows of food, water, energy, carbon, municipal solid waste, wastewater and spatial extent of ecosystem conservation. The county diagnostic fills the gap in regional environmental planning in the USA by bridging urban and state level planning. Contents Existing Footprinting Methods and the Need for Regional Ecological Planning in the USA The Urban Metabolism and Flows of the Anthroposphere The Dissipative Ecological Unit (DEU) as Organizing Principle for Metabolic Analysis of Counties Calculations and Data Sources for the County Diagnostic Method A Case Study Application of the County Diagnostic to the Eastern Temperate Forest Ecoregion Comparative Vertical Waveform Diagrams for Cases and Interpretation of Case Study Results Target Groups Researchers, lecturers and students of landscape ecology, landscape and ecological planning, environmental and regional planning, landscape architecture County engineers and managers, councils of government (COGs), regional planners in public and private practice, US environmental management agencies The Author Dr. Bryce Lawrence is a research scientist and educator at the Department of Landscape Ecology and Landscape Planning at the TU Dortmund University’s Faculty of Spatial Planning in Germany.
    Materialart: Online-Ressource
    Seiten: XX, 268 p. 67 illus., 37 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783658286163
    Serie: Beiträge zur Landschafts- und Umweltplanung I Contributions to Landscape and Environmental Planning,
    URL: https://doi.org/10.1007/978-3-658-28616-3
    DOI: 10.1007/978-3-658-28616-3
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 60
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    Online-Ressource
    Strategic Corporate Conservation Planning : A Guide to Meaningful Engagement (2020)
    Washington, DC :Island Press/Center for Resource Economics :
    Details
    Schlagwort(e): Sustainability. ; Economics. ; Business ethics. ; Sustainability. ; Economics. ; Business Ethics.
    Beschreibung / Inhaltsverzeichnis: Preface -- An Evolving Relationship -- Understanding Business Drivers -- Scale and Perspective -- The Process -- Obstacles and How to Overcome Them -- Monitoring, Metrics, and Recognition -- Education -- Climate Change -- Building a Culture of Corporate Conservation -- Acknowledgments -- Notes -- Index.
    Kurzfassung: "Under Margaret's leadership, the Wildlife Habitat Council helped General Motors streamline our conservation efforts across our global facilities, putting a strong framework in place to create measurable environmental results, as well as business value. In this book, she gives everyone the tools to create beautiful and sustainable corporate lands, offer opportunities for employee engagement, and support the communities where we live and work. Dane Parker, Vice President of Sustainable Workplaces, General Motors "Our economy and society depend on a healthy, natural world. This book tells a powerful story about how critical the business community, with its vast land holdings, is to solving the dual crises of biodiversity loss and rampant climate change. O'Gorman then shows us how to build a strategic program of conservation that works for business and the planet. This well-written and enjoyable book is an important read for those who want to leverage business to build a thriving world. Andrew Winston, advisor to multinationals and author of "Green to Gold" and "The Big Pivot" "Again and again, business is called on to be part of the solution to environmental, climate, and community problems. Margaret O'Gorman presents a practical approach to mainstream nature into industry, and in so doing, bring benefit to communities and address climate concerns. Mary Robinson, former president of Ireland; Chair, Mary Robinson Foundation–Climate Justice; Chair, The Elders "Margaret O'Gorman's masterful book is an encouraging revelation: a wonderfully written, thoughtful analysis and compilation of the little-heralded world of corporate effort at better environmental behavior. Complete with thoughtful commentary and recommendations, it should be required reading for corporate leadership and the environmental leaders who work with them. Thomas E. Lovejoy, University Professor of Environmental Science and Policy, George Mason University.
    Materialart: Online-Ressource
    Seiten: XIV, 262 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9781610919418
    URL: https://doi.org/10.5822/978-1-61091-941-8
    DOI: 10.5822/978-1-61091-941-8
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 61
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    Online-Ressource
    Housing Policy and Vulnerable Families in The Inner City : Public Housing in Harlem, New York City (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Human geography. ; Sociology, Urban. ; Social structure. ; Equality. ; Human Geography. ; Urban Sociology. ; Social Structure.
    Beschreibung / Inhaltsverzeichnis: 1. The Status Quo: Observations on a Gentrified Harlem -- 2. Rise and Fall: Harlem Renaissance and Ghettoization -- 3. Urban Poverty in Theory -- 4. Public Housing -- 5. Listening to Harlem: Tenants, Activists, Experts -- Conclusion: Understanding Harlem: The Making of a Mixed-Income Neighbo.
    Kurzfassung: This book provides insights in how the lack of coherent social policy leads to the displacement of vulnerable low-income families in inner-city neighborhoods facing gentrification. First, it makes a case for how social policy by its racist setup has failed vulnerable families in the history of U.S. public housing. Second, it shows that today’s public housing transformation puts the same disadvantaged socio-economic clientele at risk, while the neighborhoods they call their homes are taken over by gentrification. It raises the powerful argument that the continuing privatization of Housing Authorities in the U.S. will likely lead to greater income diversity in formerly neglected neighborhoods, but it will happen at the expense of vulnerable families being displaced and resegregated further outside the city, if no regulatory planning measures for their protection are initiated by the government. By providing a solid empirical portrait of public housing in New York City’s Harlem, this book provides a great resource to students, academics and planners interested in gentrification with specific concern for race and class. .
    Materialart: Online-Ressource
    Seiten: IX, 75 p. 2 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030428495
    Serie: SpringerBriefs in Geography,
    URL: https://doi.org/10.1007/978-3-030-42849-5
    DOI: 10.1007/978-3-030-42849-5
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 62
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    Online-Ressource
    Promoting the Sustainable Development Goals in North American Cities : Case Studies & Best Practices in the Science of Sustainability Indicators (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Human geography. ; Environmental policy. ; Physical geography. ; Sustainability. ; Human Geography. ; Environmental Policy. ; Physical Geography.
    Beschreibung / Inhaltsverzeichnis: Chapter1: Introduction: Localizing SDG Goals and empowering cities and communities in North America for sustainability -- SectionI: City & Regional Localization of SDGs -- Chapter2: Localizing the SGDs in Baltimore: Challenges and Opportunities of the USA Sustainable Cities Initiative -- Chapter3: Los Angeles: Measuring Its Ambition to Achieve the SDGs -- Chapter4: The Idea of Sustainability and the Houston Region -- SectionII: Programs and Tools to support the implementation of the SDGs -- Chapter5: Making the SDGs Relevant for Cities: Using the Community Capital Tool in British Columbia -- Chapter6: How Local Communities Can Align with United Nations Sustainable Development Goals: A Santa Cruz County Case Study -- SectionIII: Mobilizing Local SDG efforts across North America -- Chapter7: Top-down and Bottom-Up Approaches to the SDG-Monitoring Challenge -- Chapter8: Data for Good for All – Enabling All Communities to Track Progress Towards SDG Implementation -- SectionIV: Developing new methods and data to localize SDGs -- Chapter9: Helping the Neighborhood Create Indicators for Sustainable Housing Planning, Sustainable Development Goal #11 Sustainable Cities & Communities -- Chapter10: How the Youth Social Enterprise (YSE) Model Supports the Implementation of the Sustainable Development Goal #8 Economic Growth and Decent Work in American Cities -- SectionV: Goals, Targets and Indicators for Localizing SDGs in the US -- Chapter11: Proposed Local SDG Indicators for US Cities and Communities.
    Kurzfassung: This volume presents North American best practices and perspectives on developing, managing and monitoring indicators to track development progress towards the Sustainable Development Goals (SDGs) in local communities and cities. In 4 main sections, the book presents and frames the many ways in which community indicator programs are either integrating or retooling to integrate the SDGs into their existing frameworks, or how they are developing new programs to track and report progress on the SDGs. This is the first volume that focuses on SDG adoption within the context of North Americans cities and communities, and the unique issues and opportunities prevalent in these settings. The chapters are developed by experienced academics and practitioners of community planning and sustainable development, and will add broad perspective on public policy, organizational management, information management and data visualization. This volume presents a case-study approach to chapters, offering lessons that can be used by three main audiences: 1) teachers and researchers in areas of urban, regional, and environmental planning, urban development, and public policy; 2) professional planners, decision-makers, and urban managers; and 3) sustainability activists and interested groups.
    Materialart: Online-Ressource
    Seiten: VII, 160 p. 118 illus., 48 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030591731
    Serie: Sustainable Development Goals Series,
    URL: https://doi.org/10.1007/978-3-030-59173-1
    DOI: 10.1007/978-3-030-59173-1
    DDC: 304.2
    Sprache: Englisch
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  • 63
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    Online-Ressource
    The Home of the Future : Digitalization and Resource Management (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Sustainable architecture. ; Urban economics. ; Technological innovations. ; Sustainability. ; Sustainable Architecture/Green Buildings. ; Urban Economics. ; Innovation and Technology Management.
    Beschreibung / Inhaltsverzeichnis: Sustainable Living Spaces and Open Digital Innovation Hub -- Water -- Energy -- Food -- Enabling Technology: Internet of Things(IOT) -- Home Management System: Artifical Intelligence -- Demand Response and Smart Charging -- Blockchain and Peer-to-Peer Trading.
    Kurzfassung: This book presents an in-depth study to show that a sustainable future urban life is possible. To build a safer and more sustainable future, as humankind, we would like to use more renewable energy, increase energy efficiency, reduce our carbon and water footprints in all economic sectors. The increasing population and humans’ ever-increasing demand for consumption pose another question whether the world’s resources are sufficient for present and future generations. Fair access to water, energy, and food is the objective for all. In line with the United Nations Sustainable Development Goals, scientists, researchers, engineers, and policymakers worldwide are working hard to achieve these objectives. To answer all these challenges, we would like to introduce the core of Smart Cities of the future, the building block of the future’s urban life: Open Digital Innovation Hub (ODIH). ODIH will serve as the ‘Home of the Future’, a fully digitalised and smart, self-sustaining building that answers all the motivation we highlight here. In ODIH, we introduce a living space that produces its water, energy, and food by minimising carbon and water footprints thanks to the Internet of Things, Artificial Intelligence, and Blockchain technologies. It will also serve as an open innovation environment for start-ups and entrepreneurs who wish to integrate their solutions into the infrastructure of ODIH and test those in real-time. We believe this will be a true open innovation test-bed for new business models.
    Materialart: Online-Ressource
    Seiten: XIII, 258 p. 162 illus., 140 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030750930
    Serie: Sustainable Development Goals Series,
    URL: https://doi.org/10.1007/978-3-030-75093-0
    DOI: 10.1007/978-3-030-75093-0
    DDC: 304.2
    Sprache: Englisch
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  • 64
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    Online-Ressource
    The Impact of the COVID-19 Pandemic on Green Societies : Environmental Sustainability (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Environmental management. ; Environmental health. ; Soil science. ; Pollution. ; Sustainability. ; Environmental Management. ; Environmental Health. ; Soil Science. ; Pollution.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. COVID-19: An Opportunity for Smart and Sustainable Cities in India -- Chapter 2. Re-assessment of Urban Sustainability and Food Security in the light of COVID-19 -- Chapter 3. Disruptive Mobility in pre-and post-COVID times: App-based Shared Mobility in Indian Cities- a Case of Bengaluru -- Chapter 4. Finding the Long-Lost Path: Developing Environmental Awareness through the Pandemic -- Chapter 5. The Dual Impact of Lockdown on Curbing COVID-19 Spread and Rise of Air Quality Index in India -- Chapter 6. Aftermath of Industrial Pollution, Post COVID-19 Quarantine on Environment -- Chapter 7. Covid-19: Disaster or an Opportunity for Environmental Sustainability -- Chapter 8. COVID-19 and its Impact on Carbon Dioxide Emissions -- Chapter 9. Sustainable Attainment of Solar E-waste Recycling concerning to COVID-19 Crisis: A Review -- Chapter 10. Impact of Biomedical Waste Management System on Infection Control in the Midst of Covid-19 Pandemic -- Chapter 11. Sludge hygienisation – a novel technology for urban areas to deal with incursion of COVID-19 viral particles in wastewater -- Chapter 12. Trends and Innovations in Biosensors for COVID-19 Detection in Air -- Chapter 13. IoT Based Wearable Healthcare System: Post COVID-19 -- Chapter 14. Biodiversity Conservation: An imperial need in combatting pandemic and healthcare emergencies -- Chapter 15. COVID-19 Pandemic: an Unprecedented Blessing for Nature -- Chapter 16. Green Economy Approach to Develop Bioactive Dexamethasone Analogue Scaffold against SARS CoV-2.
    Kurzfassung: This book covers the sustainability issues of a green environment towards economics and society in terms of alteration in industrial pollution levels, effect of reduced carbon emissions, changes in water bodies characteristics with respect to heavy metal contamination, monitoring of associated impact with respect to ecology and biodiversity, impact of reduced noise levels and air quality influences on human health, handling and management of biomedical waste. According to WHO, 80% of people living in urban areas are exposed to air exceeding safe limits. The advent of "sustainability‟ in development science has led planners to apply evolving notions of "sustainability‟ to the contemporary debate over how cities and regions should be revitalized, redeveloped, and reformed. Market allocation of resources, sustained levels of growth and consumption, an assumption that natural resources are unlimited and a belief that economic growth will „trickle down‟ to the poor have been its hallmarks. The recent advance technology helps to promote green and clean modern societies continuously. The Internet of things will be playing an important role in the upcoming years in environment protection and sustainable development. There is a focus on paradigm shift in the sustainable development for the green environment during the period of isolation of COVID-19. This is the moment for the mobilization against the climate crisis. The sudden fall in pollutants and subsequent blue skies signifies a dramatic shift for India and also other affected countries during this period. Fighting climate change requires a collaborative approach between all spheres of society unlike the former. It must heavily redirect resources towards local, sustainable activities, including education, health, sustainable agriculture and circular management of resources. The impact of COVID-19 pandemic which has resulted in the dramatic change in the different aspects of the environment. The global lockdown has led to a rejuvenation of nature, ecosystems, biodiversity. Even urban environments are discovering a degree of peace and serenity, which led to decrease in greenhouse gas emission.
    Materialart: Online-Ressource
    Seiten: X, 434 p. 242 illus., 108 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030664909
    URL: https://doi.org/10.1007/978-3-030-66490-9
    DOI: 10.1007/978-3-030-66490-9
    DDC: 304.2
    Sprache: Englisch
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  • 65
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    Cities of the Future : Challenges and Opportunities (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Human geography. ; Landscape ecology. ; Geography. ; Architecture. ; Urban economics. ; Human Geography. ; Landscape Ecology. ; Regional Geography. ; Cities, Countries, Regions. ; Urban Economics.
    Beschreibung / Inhaltsverzeichnis: Future of Smart Inclusive Livable Cities -- Smart Environmental Solutions in Future Cities -- Mobility & Infrastructure in Future Cities -- Smart Economic Solutions in Future Cities -- Governance and Community Development in Future Cities -- Saudi Cities Future.
    Kurzfassung: This book seeks to address the key challenges and opportunities of "future cities" embracing novel approaches and grounded technologies in pursuing a vision for smart, inclusive cities. The objective of this book is to discuss multiple areas at the local, national, and international levels and how these challenges can hinder the development objectives planned to be achieved by the cities of the future. The chapters featured in this collection were presented at the 6th Memaryat International Conference (MIC 2022), held at the Effat University, Jeddah. MIC’s objective is to build bridges between science, technology, and innovation, seen as the key levers of attaining the SDGs. This book provides the most innovative ideas presented at the conference to address the key manifestation of “future cities" to embrace novel approaches and grounded technologies in the pursue of a vision for smart inclusive cities. It thus represents a platform for diverse contributions from academics and practitioners to present their different perspectives addressed theoretically as well as in practice concerning the challenges and opportunities of future cities. This includes contributions from decision-makers, architects, urban planners, urban designers, entrepreneurs, and educators to stimulate discussion covering the latest on the challenges and opportunities for better future cities in the different domains of architecture, building science and technology, environmental design, mobility & infrastructure, urban design & landscape, housing & real estate developments, urban planning, governance, socio-cultural & economic development, community engagement, tourism and heritage revitalization.
    Materialart: Online-Ressource
    Seiten: XIV, 258 p. 114 illus., 93 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031154607
    URL: https://doi.org/10.1007/978-3-031-15460-7
    DOI: 10.1007/978-3-031-15460-7
    DDC: 304.2
    Sprache: Englisch
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  • 66
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    Housing and Technology : Special Focus on Zimbabwe (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Human geography. ; Sociology, Urban. ; Buildings Design and construction. ; Geography. ; Real estate business. ; Human Geography. ; Urban Sociology. ; Building Construction and Design. ; Regional Geography. ; Real Estate Economics.
    Beschreibung / Inhaltsverzeichnis: 1. The Housing and Technology Nexus: An Overview -- 2. The Context of Housing and Technology in Zimbabwe -- 3. Housing-Technology Differentiation and Typologies -- 4. Housing Delivery, Management and Technology -- 5. Socio-Cultural, Ecological and Economic Issues in Housing and Technology, and the Politics -- 6. Towards Sustainable Policies for Housing and Technology in Zimbabwe. .
    Kurzfassung: The housing and human settlement sector is fast changing, and technology is making it more complex than ever before. With reference to Zimbabwe, a developing country in Southern Africa, the essence of this book is to bring out housing as an issue within the technology debate and practice. The following themes emerge from the 6 chapters in the book: • The characterisation and conceptualisation of housing and technology and the nexus of both • The complexity of housing challenges and the problems governments face in providing adequate housing, especially for the poor • Diverse practices in housing construction through the application of different typologies of technology • Assessment of the feasibility of technologies in housing development in Zimbabwe by mirroring them against global experiences. • Discussion of alternative policy approaches that may guide technology integration in housing development. This book will excite scholars and practitioners in urban and development studies, construction project management, urban sociology, geography, real estate together with policymakers and government officials. .
    Materialart: Online-Ressource
    Seiten: XI, 117 p. 20 illus., 19 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031090981
    Serie: SpringerBriefs in Environment, Security, Development and Peace, 37
    URL: https://doi.org/10.1007/978-3-031-09098-1
    DOI: 10.1007/978-3-031-09098-1
    DDC: 304.2
    Sprache: Englisch
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  • 67
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    The Trialism and Application of Human Settlement, Inhabitation and Travel Environment Studies : Applications in Water-net Region (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Human geography. ; Landscape architecture. ; Human ecology Study and teaching. ; Human Geography. ; Landscape Architecture. ; Environmental Studies.
    Beschreibung / Inhaltsverzeichnis: Chinese Human Settlements Philosophy -- The Origin of Trailism of Human Settlement, Inhabitation and Travel Environment -- Three elements and Main Factors Analysis on Human Settlement, Inhabitation and Travel Environment -- The Evolution of the Human Settlement, Inhabitation and Travel Environment Theory -- The Classification and Characteristics of the Human Settlement, Inhabitation and Travel Environment Background -- Analysis and Evaluation on Activity in Human Settlement, Inhabitatin and Travel Environment -- Human Settlement, Inhabitation and Travel Environment Construction Theory and Technology.-Human Settlement, Inhabitation and Travel Environment Studies in Water-net Region -- Human Settlement, Inhabitation and Travel Environment Studies in Valley Region.
    Kurzfassung: This book studies human settlements in China in terms of Human Settlements Trialism in 5 typical human settlement types: river valleys, water networks, hills, plains, and arid areas. Focusing on 3 elements of Trialism—(1) natural and constructed environments, resources, and visual landscapes in human settlements background; (2) survival strategies, customs, culture, and values in human settlements activity; and (3) the layout of time and space as well as the planning and design of the urban, the country, and the wilderness in human settlements construction—the book analyzes the evolution of human settlements and predicts future trends. Presenting academic researchers and graduate students in various fields with insights from landscape architecture, urban planning, architecture, geography, forestry, art, and psychology, the study discusses the principles of interactive physiological thinking and systematically theoretical philosophy related to professional physiology, planning and design principles, and traditional and modern methods and technologies in urban and rural construction. The innovative multi-discipline study promotes the planning and design of 5 types of human settlement, which is helpful to the judgment of value, activity rule, and living style of human settlements, and also discusses the development of human settlements in the new millennium.
    Materialart: Online-Ressource
    Seiten: XX, 344 p. 70 illus., 49 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811991431
    URL: https://doi.org/10.1007/978-981-19-9143-1
    DOI: 10.1007/978-981-19-9143-1
    DDC: 304.2
    Sprache: Englisch
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  • 68
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    Concepts and Approaches for Sustainability Management (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Sustainability. ; Management. ; Environmental education. ; Sustainability. ; Management. ; Environmental and Sustainability Education.
    Beschreibung / Inhaltsverzeichnis: Linking Corporate Social Responsibility of Chemical Industries to Sustainable Development -- Integrating Responsible Care into Quality, Environmental, Health and Safety Management System -- Adopting and Implementing Product Stewardship for Sustainable Industrial Management -- Developing Nanotechnology for the Public Wellbeing towards Sustainable Development -- Streamlining Non-Governmental Organization’s Programs towards Achieving Sustainable Development Goals -- Integrating Sustainability Concept into Chemistry Curriculum for Education for Sustainable Development -- Shifting the Paradigm of Urban River towards Integrated Stormwater Management.
    Kurzfassung: Since the release of the 2030 Agenda for Sustainable Development by the United Nations General Assembly in September 2015, UN agencies, member states and stakeholders have increasingly begun focusing on the adoption and implementation of these strategies to achieve the 17 Sustainable Development Goals. To work towards sustainability, strategic measures to encourage stakeholders to contribute to the goals of the 2030 agenda are called for. To that end, this book presents research concepts and approaches to the sustainable management of industries, products, technologies, communities, education and the environment. In addition to assessing these approaches, it includes a wealth of case studies that share valuable insights and guidance on the way forward. The book is chiefly intended for sustainable development practitioners, including researchers, government agencies, industries, NGOs and communities interested in adopting sustainable concepts and approaches.
    Materialart: Online-Ressource
    Seiten: VII, 118 p. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030345686
    Serie: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    URL: https://doi.org/10.1007/978-3-030-34568-6
    DOI: 10.1007/978-3-030-34568-6
    DDC: 304.2
    Sprache: Englisch
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  • 69
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    Online-Ressource
    The Principles of Green and Sustainability Science (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Environmental education. ; Environmental management. ; Sustainability. ; Environmental and Sustainability Education. ; Environmental Management.
    Beschreibung / Inhaltsverzeichnis: Part 1. Introductory Context and Principles of Green -- Chapter 1. The Principles of Green -- Chapter 2. Basic Ecology -- Chapter 3. Everyday Activities in the Green World -- Chapter 4. Effects of Everyday Activities on the Ecosystem -- Part 2. Green Practices and Environmental Responsibility -- Chapter 5. Health and Diseases -- Chapter 6. Renewable Energy -- Chapter 7. Water and Wastewater Treatment -- Chapter 8. Waste Management -- Chapter 9. Environmental Ethics -- Part 3. Principles and Practices of Sustainability -- Chapter 10. Sustainability -- Chapter 11. Green Entrepreneurship -- Chapter 12. Sustainability in Science -- Chapter 13. The Future: Achieving Sustainability.
    Kurzfassung: This book uses the concept of sustainability in science to address problems afflicting the environment, and to devise measures for improving economies, societies, behaviors, and people. The book pursues a scientific approach, and uses scientific evidence as the basis for achieving sustainability. The key topics addressed include: unemployment, health and disease, unsustainable production, our common future, renewable energies, waste management, environmental ethics, and harmful anthropogenic activities. Whereas past literature has mainly examined sustainability as an environmental issue, this book expands the conversation into various sciences, including mathematics, biology, agriculture, computer science, engineering, and physics, and shows how sustainability could be achieved by uniting these fields. It offers a wealth of information across various disciplines, making it not only an intriguing read but also informative and insightful.
    Materialart: Online-Ressource
    Seiten: XXIX, 407 p. 83 illus., 73 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811524936
    URL: https://doi.org/10.1007/978-981-15-2493-6
    DOI: 10.1007/978-981-15-2493-6
    DDC: 304.2
    Sprache: Englisch
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  • 70
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    Geoecology of Landscape Dynamics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Human geography. ; Landscape ecology. ; Sustainability. ; Geographic information systems. ; Human Geography. ; Landscape Ecology. ; Sustainability. ; Geographical Information System.
    Beschreibung / Inhaltsverzeichnis: Land use land cover dynamics using Remote Sensing and GIS techniques in Western Doon Valley, Uttarakhand, India -- Spatial analysis and mapping of malaria risk in Dehradun city India: A geospatial technology based decision making for planning of control -- Sustainable Energy Development and Participatory Management Scenario in Sundarbans: A Case Study from Sagar Island, West Bengal, India -- Robust and reliable technique of automatic building extraction from high resolution imagery -- Soil Resource Inventory for Meeting Challenges of Land Degradation: A Remote Sensing Approach -- Controlling Challenges of Urban Surface Run-Off Water: A Sustainable Approach -- Hydrological Modeling Using SWAT Model and Geoinformatic Techniques -- Green Buildings: Building a Greener City, a Greener Future An Indian Perspective -- Human Capital Impact for Sustainable Economic Growth -- Temporal variation in glacier’s area and Identification of glacial lakes in Sikkim -- UN SDGs and context of Heritage cities in India: a study of Ayodhya and Varanasi -- Morphometric Analysis of the Yerla Watershed of the Krishna River Basin using Spatial Information Technology -- Conceptualising and Measuring Social Capital as a Sustainable Development Strategy in Mewat Region, Haryana -- Analysing the capability of NCI technique in change detection using high and medium resolution multispectral data -- Monitoring and Modelling of Urban Sprawl Using Geospatial Techniques: A Case Study of Shimla City, India -- Comparison of Multi Temporal Drought Indices Using Monthly Precipitation in the Western Part of the West Bengal -- Dying and Dwindling of Non-Glacial Fed Rivers Under Climate Change: A Case Study from The Upper Kosi Watershed, Central Himalaya, India) -- Planning of Integrated Land use & Social Infrastructure of SAS Nagar (Mohali) -- Agroforestry Ecosystem in Himalayan Region of Uttarakhand Using Remote Sensing and Geographic Information System -- A study of Development along Delhi-Jaipur Express using Geospatial Technology -- Slope Vulnerability, Mass Wasting and Geohydrological-hazards in Himalaya: A Case Study of Alaknanda Basin, Uttarakhand, India -- Demarcation of Hyper Arid Land in the Indian Desert: An Environmental Analysis. .
    Kurzfassung: This book provides an overview of the ecological indicators of landscape dynamics in the context of geographical landscape integration. Landscape dynamics depicts every change that occurs in the physical, biological, and cognitive assets of a landscape. To understand and interpret the complex physical, biological, and cognitive phenomena of landscapes, it is necessary to operate conceptually and practically on a broad range of spatial and temporal scales. Rapid land use changes have become a concern to environmentalists and planners because of their impacts on the natural ecosystem, which further determines socioeconomic dynamics. In this regard, the book discusses case studies that share new insights into how landscape patterns and processes impact small creatures, and how small creatures in turn influence landscape structure and composition. In turn, the relevant aspects of land use and land cover dynamics are covered, and the multi-faceted relationship between the substrata and ecological community is highlighted. The book is unique in its focus on the application of spatial informatics such as automatic building extraction from high-resolution imagery; a soil resource inventory for meeting the challenges of land degradation; hydrological modeling; the temporal variation analysis of glacier area and the identification and mapping of glacial lakes; morphometric analysis of river basins; and the monitoring and modeling of urban sprawl, among other features.
    Materialart: Online-Ressource
    Seiten: IX, 381 p. 150 illus., 132 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811520976
    Serie: Advances in Geographical and Environmental Sciences,
    URL: https://doi.org/10.1007/978-981-15-2097-6
    DOI: 10.1007/978-981-15-2097-6
    DDC: 304.2
    Sprache: Englisch
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    Competing for Land, Mangroves and Marine Resources in Coastal Vietnam (2021)
    Dordrecht :Springer Netherlands :
    Details
    Schlagwort(e): Environmental sciences Social aspects. ; Water. ; Hydrology. ; Biotechnology. ; Environmental Social Sciences. ; Water. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction: Mangrove Systems Facing Enclosures, Markets and Social Inequality -- Chapter 2. Early History of Mangrove Management in Giao Lạc -- Chapter 3. Socialism, Cooperatives and Mangrove Management in Giao Lạc (1954-1985) -- Chapter 4. Impacts of Economic Renovation on Households and Coastal Ecosystems -- Chapter 5. Social Differentiation under Đổi mới Reforms -- Chapter 6. Conclusions.
    Kurzfassung: This book presents a historical and ethnographic study of changing mangrove management in northern Vietnam over the past 100 years, grounded in a case study in the Red River Delta in northern Vietnam. The book shows that three primary socio-economic dynamics have affected mangroves: enclosure movements that have restricted access by different user communities over time, such as the exclusion of women; changing valuation of mangroves and their products and services; and social and class differentiation caused by privatization of once common resources. The result of these pressures have been erosions of norms, rules, and collective action to protect and nurture mangroves, leading to widespread loss of coastal forests. Sustainable mangrove management will require attention to these dynamics to address current-day land conflicts. The book will be of interest to policy-makers, practitioners, and academics and students in forest policy, management and governance; rural livelihoods; and globalization and agrarian change. .
    Materialart: Online-Ressource
    Seiten: XVII, 171 p. 13 illus., 8 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789402421095
    Serie: MARE Publication Series, 24
    URL: https://doi.org/10.1007/978-94-024-2109-5
    DOI: 10.1007/978-94-024-2109-5
    DDC: 304.2
    Sprache: Englisch
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  • 72
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    The Route Towards Global Sustainability : Challenges and Management Practices (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Environmental management. ; Power resources. ; Environmental economics. ; Economic policy. ; Social policy. ; Sustainability. ; Environmental Management. ; Resource and Environmental Economics. ; Socio-Economic Policy.
    Beschreibung / Inhaltsverzeichnis: Chapter 1-Planning model to provide a practical understanding of sustainability perspectives -- Chapter 2-Local Sustainability: measuring the achievement of the urban indicators -- Chapter 3-Assessing regional sustainability by indicators: implications and emerging challenges -- Chapter 4-Integrated Water Resources Management and urban sustainability -- Chapter 5-Smart Cities and sustainability indicators: a structure proposal -- Chapter 6-Educational factors influencing higher education organizations -- Chapter 7-PRME signatory schools and the Interdisciplinary Approach at Education for Sustainable Development -- Chapter 8-Perspectives across education institution and role to sustainable competencies -- Chapter 9-Promoting stakeholders engagement to make feasible, sustainable development -- Chapter 10-The influence on sustainability practices by stakeholders -- Chapter 11-Managing stakeholders for regional sustainability: challenges and mechanisms -- Chapter 12-Understanding and participatory learning the social impact of sustainability perspectives -- Chapter 13-Corporate Social Responsibility and roles of developers for sustainability in companies -- Chapter 14-Waste management: extending beyond local boundaries -- Chapter 15-Observing technologies to environmental sustainability management -- Chapter 16-Access to sanitation services and human health and gender in emerging economies. -- Chapter 17-Assessing sanitation conditions under the SDGs: assisting SDG 6 -- Chapter 18-Risk management and pandemic moment: what is the role of sustainability management?- Chapter 19-Getting the global goals to sustainability in pandemic time: Are we out of track?- Chapter 20. Environmental management and sanitation: Perspectives on waste.
    Kurzfassung: This volume discusses topics of global sustainability involving sustainability indicators, stakeholders' participation, and technological and strategic advances with the goal of "thinking locally to act globally". Scientists, academics, policymakers, and planners are currently focused on escalating global socioeconomic and ecological issues, such as rising inequality, adverse anthropogenic impacts on the environment, and deficiencies in natural resources. These variables are pushing the earth system's resistance capacity past its breaking point, with additional pressures incurred by a global pandemic. Therefore, this book looks to impart knowledge on participatory learning action research for human and environmental health and well-being. Sustainable development planning and management are needed in these pressing circumstances, and they necessitate an analytical interpretation of ongoing processes, current and future challenges, and an understanding of available tools and technologies. The main sections of the book focus on challenges and management practices for global sustainability, promoting educational values, smart initiatives in urban contexts, and integrating emerging sustainability dimensions in policies and legislation. The primary audience for the work is policy makers, urban planners, social scientists, economists, NGOs, and students, researchers, and educators engaged in environmental social science and sustainability management. .
    Materialart: Online-Ressource
    Seiten: VIII, 429 p. 13 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031104374
    URL: https://doi.org/10.1007/978-3-031-10437-4
    DOI: 10.1007/978-3-031-10437-4
    DDC: 304.2
    Sprache: Englisch
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    Sustaining our Environment for Better Future : Challenges and Opportunities (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Water. ; Hydrology. ; Power resources. ; Environmental education. ; Environmental management. ; Sustainability. ; Water. ; Natural Resource and Energy Economics. ; Environmental and Sustainability Education. ; Environmental Management.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Thoughts On Economic Progress: The Controversy Between Neoclassical Economics And Sustainable Economies -- Chapter 2. Mining Environmental Disasters in North and South America -- Chapter 3. Rural Development In Africa: Challenges and Opportunities -- Chapter 4. Regenerating the Pearl of the Pacific: A Destination Capitals Approach to Acapulco’s Tourism Development -- Chapter 5. Relationship Between Women, Environment Towards Sustainable Development: A Case Study From Palestine -- Chapter 6. Water contamination and health hazards in pakistan: an overview of the current scenario and contemporary challenges -- Chapter 7. water security: challenges to the irrigation water-energy nexus in Australia -- Chapter 8. Sustaining Queensland’s Agricultural Sector: Challenges and Opportunities from the Bioeconomy and the Circular Economy -- Chapter 9. Creating Sustainable Energy For Future Generations -- Chapter 10. Sustainable Consumption Behavior Among Romanian Students -- Chapter 11. Validity Testing Of A Heat Transfer Model In A Greenhouse -- Chapter 12. Deforestation in Malaysia: The Current Practice and the Way Forward -- Chapter 13. Meeting The Stakeholder Needs And Sustaining Business Through Sustainability Risk Management Practices: A Case Study Of Malaysian Environmentally Sensitive Companies -- Chapter 14. Smart Cities and their Role in the Framework of the Sustainable Development Goals. .
    Kurzfassung: This book covers a variety of topics regarding environmental practices in our day-to-day lives, as well as topics concerning sustainable development as a broader concept embracing ecological, social, and economic aspects to improve the quality of life for people around the world. Starting with the traditional controversy between the neoclassical economy and sustainable economy, which may be overcome by scientific progress due to more intensive scientific studies of the sustainability paradigm, the book proceeds to discuss various problems and challenges regarding environmental protection and sustainable development in different countries and on different continents. This includes analyses of recent, sometimes fatal mining disasters in South and North America, challenges and opportunities for rural development in Africa and Australia, an exploration of the role of women for sustainable development in Palestine, water safety and water security issues in Asia and Australia, the environmental exploitation of popular tourism destinations like Acapulco, and deforestation in Malaysia, suggesting innovative approaches to turn challenges into opportunities to effectively tackle these problems. Other topics addressed involve sustainable energy creation for future generations, a research survey among Romanian students on sustainable consumption behavior, validity testing for a heat transfer model in a greenhouse, and a case study on sustainability risk management practices at Malaysia’s environmentally sensitive companies. The book closes with an examination of highly digitalized Smart Cities as a potentially valuable complement to conventional urban and rural lifestyles in connection with achieving the UN Sustainable Development Goals (SDGs). .
    Materialart: Online-Ressource
    Seiten: XXIV, 257 p. 38 illus., 37 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811371585
    URL: https://doi.org/10.1007/978-981-13-7158-5
    DOI: 10.1007/978-981-13-7158-5
    DDC: 304.2
    Sprache: Englisch
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    Water-Energy-Nexus in the Ecological Transition : Natural-Based Solutions, Advanced Technologies and Best Practices for Environmental Sustainability (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Water-power. ; Energy policy. ; Water. ; Hydrology. ; Sustainability. ; Hydroenergy. ; Energy System Transformation. ; Water.
    Beschreibung / Inhaltsverzeichnis: About the Editors -- Preface -- Keynotes -- Track 1: Nexus framework and governance -- Track 2: Advanced technologies and nature-based solutions for the environmental sustainability of the water sector -- Track 3: Control of hazardous substances and recovery of renewable/valuable resources -- Track 4: Energy-saving technologies and future clean energy solutions -- Track 5: Implementation and best practices.
    Kurzfassung: This book includes selected contributions presented during the 3rd edition of the international conference on WaterEnergyNEXUS, which was held in Tunisia in December 2020. This conference was organized by the University of Sfax (Tunisia), in cooperation with the Sanitary Environmental Engineering Division (SEED) of the University of Salerno (Italy), the Advanced Institute of Water Industry at Kyungpook National University (Korea) and The Energy and Resources Institute, TERI (India). The WaterEnergyNEXUS series of conferences are supported by the UNESCO World Water Association Programme (WWAP) and the International Water Association (IWA). It also enjoys the patronage of several international scientific societies, associations and organizations and has established a publishing partnership with Springer Nature. With the support of international experts invited as plenary and keynote speakers, the conference aimed to give a platform for Euro-Mediterranean countries to share and discuss key topics on such water-energy issues through the presentation of nature-based solutions, advanced technologies and best practices for a more sustainable environment within the framework of the ecological transition. This book gives a general and brief overview of current research focusing on emerging Water-Energy-Nexus issues and challenges and their potential applications to various environmental problems impacting the Euro-Mediterranean zone and surrounding regions. A selection of novel and alternative solutions applied worldwide are included. The book contains over about one hundred carefully refereed contributions from 48 countries worldwide selected for the conference. Topics covered in the book include: nexus framework and governance; economic evaluations for investment projects in the water and energy sectors; innovation of renewable energies and challenges for the mitigation of climate change impact in the water-energy-food-nexus; advanced technologies and nature-based solutions for the environmental sustainability of the water sector; water and wastewater technologies for developing countries; green technologies for sustainable water and wastewater management; advanced technologies and nature-based solutions in water cycle; control of hazardous substances and recovery of renewable/valuable resources; renewable/valuable resources for recovery and utilization; control of nutrients and hazardous compounds; energy-saving technologies and future clean energy solutions; future urban-energy systems with considerations of water and food security; environmental biotechnology and bioenergy; implementation and best practices. This book is also an invaluable guide for industry professionals and policymakers working in the water and energy sectors. .
    Materialart: Online-Ressource
    Seiten: XVIII, 481 p. 178 illus., 138 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031008085
    Serie: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    URL: https://doi.org/10.1007/978-3-031-00808-5
    DOI: 10.1007/978-3-031-00808-5
    DDC: 304.2
    Sprache: Englisch
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  • 75
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    Sustainable Bioeconomy : Pathways to Sustainable Development Goals (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Environmental Law. ; Environmental management. ; Energy policy. ; Energy and state. ; Environment. ; Sustainability. ; Environmental Law. ; Environmental Management. ; Energy Policy, Economics and Management. ; Environmental Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Exploring the economics of the circular bioeconomy -- Chapter 2.The role of culture and moral responsibility in facilitating a sustainable bioeconomy -- Chapter 3. Social and economic contribution of the bioeconomic sector in Ecuador: A methodological approach -- Chapter 4. Biobutanol Production from Agricultural Biomass -- Chapter 5. Valorization of biowastes into food, fuels and chemicals - towards sustainable environment, economy and society -- Chapter 6. Sustainable biorefinery technologies for agro-residues: challenges and perspectives -- Chapter 7. Biotechnological Interventions for Production of Flavour and Fragrance Compounds -- Chapter 8. Phytochemicals for the management of stored product insects -- Chapter 9. Assessing the impact of indigenous knowledge systems on sustainable agriculture: A case study of the selected communities in the City of Tshwane Metropolitan, Gauteng Province, South Africa -- Chapter 10. Tropical biological natural resource management through integrated bio-cycles farming system -- Chapter 11. Biopesticides for Pest management -- Chapter 12. Renewable energy for a low carbon future: Policy perspectives -- Chapter 13. TNAU Energy Soft 2016: An efficient energy audit tool to identify energy saving technologies for sustainable agriculture -- Chapter 14.Mechanism for Improving the Sustainability of Homestead Food Gardens in the Gauteng Province, South Africa -- Chapter 15. Assessment of Potassium Nutrient Balance in Agricultural Farming System: A Pathway to Sustainable Production of Crops.
    Kurzfassung: Sustainable development is the most important challenge facing humanity in the 21st century. The global economic growth in the recent past has indeed exhibited marked progress in many countries. Nevertheless, the issues of income disparity, poverty, gender gaps, and malnutrition are not uncommon in the global landscape, in spite of the upward growth of the economy and technological advances. This grim picture is further exacerbated by our growing human population, unmindful resource use, ever-increasing consumption trends, and changing climate. In order to protect humanity and preserve the planet, the United Nations issued the “2030 agenda for sustainable development,” which includes but is not limited to sustainable production and consumption practices, e.g. in a sustainable bioeconomy. The hallmark of the sustainable bioeconomy is a paradigm shift from a fossil-fuel-based economy to a biological-based one, which is driven by the virtues of sustainability, efficient utilization of resources, and “circular economy.” As the sustainable bioeconomy is based on the efficient utilization of biological resources and societal transformations, it holds the immense potential to achieve the UN’s Sustainable Development Goals. This book shares valuable insights into the linkages between the sustainable bioeconomy and Sustainable Development Goals, making it an essential read for policymakers, researchers and students of environmental studies. .
    Materialart: Online-Ressource
    Seiten: XIII, 337 p. 66 illus., 50 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811573217
    URL: https://doi.org/10.1007/978-981-15-7321-7
    DOI: 10.1007/978-981-15-7321-7
    DDC: 304.2
    Sprache: Englisch
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    A Nexus Approach for Sustainable Development : Integrated Resources Management in Resilient Cities and Multifunctional Land-use Systems (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Environmental management. ; Environment. ; Energy policy. ; Energy and state. ; Economic geography. ; Environmental monitoring. ; Sustainability. ; Environmental Management. ; Environmental Sciences. ; Energy Policy, Economics and Management. ; Economic Geography. ; Environmental Monitoring.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Use of The Nexus Approach as a Tool for Resources Management in Resilient Cities and Multi-functional Land Use Systems (Hülsmann and Jampani) -- Chapter 2. How to Best Apply Information Technology to Realize a Transdisciplinary Water-Soil-Waste Nexus Approach (Bouma) -- Chapter 3. Nutrient Recovery for Use in Agriculture: Economic Assessment of Decentralized Compost Business Model in Nairobi (Gebrezgabher, Taron and Amewu) -- Chapter 4. Sustainable and Safe Reuse of Wastewater for Food Production in Peri-urban Areas of Karnataka, India (Ramakrishna and Hanisch) -- Chapter 5. Multi-functional Historical Data for Improved Management of Reservoirs (Sang and Maina) -- Chapter 6. Usefulness of Surface Water Retention Reservoirs Inspired by 'Permaculture Design'. A Case Study in Southern Spain Using Bucket Modelling (Fiebrig and Van De Wiel) -- Chapter 7. Economic Valuation of Environmental Services Associated with Agriculture in the Watershed of Lake Lagdo, Cameroon (Nje and Ayuk) -- Chapter 8. he Energy-Water Nexus in Iran: The Political Economy of Energy Subsidies for Groundwater Pumping (Jaghdani and Kvartiuk) -- Chapter 9. Political Economy of Energy Subsidies for Groundwater Irrigation in Mendoza, Argentina (Riera, Brümmer and Gennari) -- Chapter 10. Rural Resources (Including Forestry) in the Local Development of Low Carbon Economy: a Case Study of Poland (Wiśniewski) -- Chapter 11. Opportunities and Challenges to Adopt Sustainable Watershed Management Interventions: An Overview of Experiences from Ethiopia (Tesfahunegn and Ayuk) -- Chapter 12. The Potential Contribution of Cultural Ecological Knowledge in Resources Management of a Volcanic River Basin (Ariyanti, Scholten and Edelenbos) -- Chapter 13. Nexus-Oriented Approach for Sharing Water Resources: Development of Eco-industrial Parks in the Catchment of Zayandeh Rud River, Iran (von Koerber, Raber and Schneider) -- Chapter 14. City-to-City Learning within City Networks to Cater City Needs to Climate Adaptation - Results of a Preliminary Study (Haupt, Zevenbergen and van Herk) -- Chapter 15. A Participatory Multi-stakeholder Approach to Implementing the Agenda 2030 for Sustainable Development: Theoretical Basis and Empirical Findings (Eichhorn, Hans and Schön-Chanishvili).
    Kurzfassung: This book explores how integrated management of environmental resources via a nexus approach can help in achieving the respective Sustainable Development Goals (SDGs). It provides conceptual considerations but mainly practical examples on how to implement a nexus approach in cities and multifunctional land-use systems to increase resource use efficiency and develop a low carbon economy. After sketching out the background and conceptual outline, contributions to the book explore key aspects of the nexus implementation. Specifically, they • Demonstrate how to sustainably use organic waste and wastewater for agriculture, • Explore examples on how to manage multifunctional land-use systems including multipurpose reservoirs, • Highlight the importance of economic incentives for successful nexus implementation, and • Provide a comprehensive perspective on challenges and opportunities of implementation, considering peer-to-peer learning, indigenous knowledge, and stakeholder participation. The chapters in this book shed a new light on key aspects of the interrelation between SDGs and the nexus approach in resilient cities and multifunctional land-use systems, and provide specific examples on how to advance sustainable resources management. .
    Materialart: Online-Ressource
    Seiten: VI, 256 p. 64 illus., 42 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030575304
    URL: https://doi.org/10.1007/978-3-030-57530-4
    DOI: 10.1007/978-3-030-57530-4
    DDC: 304.2
    Sprache: Englisch
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    Achieving Sustainability: The Ultimate Human Challenge : Critical Barriers and Future Perspectives (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Human ecology Study and teaching. ; Social sciences Philosophy. ; Environmental policy. ; Social sciences. ; Sustainability. ; Environmental Studies. ; Social Theory. ; Environmental Policy. ; Society.
    Beschreibung / Inhaltsverzeichnis: Preface -- Introduction -- Part One: The essence of sustainability: definitions, interpretations and applications -- Part Two: The challenges of the economic development model -- Part Three: Embracing utopian thought -- Part Four: Sustainability in the current economic paradigm -- Part Five: Barriers to sustainability -- Part Six: Future perspectives - a new beginning? -- Part Seven: Conclusion.
    Kurzfassung: The book provides an assessment of whether sustainability is realizable in the current societal framework. What are the challenges and the barriers - and what are the levers necessary to meet and overcome them? Through a revision of the essence of sustainability the book provides an opportunity to understand the deeper level of the radical change that sustainability represents, and the resistance that is preventing its realization. To build the argument the sustainable development model is compared with current development theories as well as alternative solutions based on utopian models of the past. The book assesses the results that can be achieved within the current systemic framework, based on case stories. It outlines the limitations to sustainability, pointing out and defining the multiple, cross-sectoral and systemic barriers that hinder the transition. Finally, the book offers perspectives on achieving a sustainable future, encompassing the impacts from recent events including the pandemic as well as the multiple mitigation and transition initiatives undertaken globally. Brian Goodwin's Quote Like the caterpillar that wraps itself up in its silken swaddling bands prior to its metamorphosis into a butterfly, we have wrapped ourselves in a tangled skin from which we can emerge only by going through a similarly dramatic transformation.
    Materialart: Online-Ressource
    Seiten: XX, 162 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031100239
    URL: https://doi.org/10.1007/978-3-031-10023-9
    DOI: 10.1007/978-3-031-10023-9
    DDC: 304.2
    Sprache: Englisch
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    Online-Ressource
    Green Engineering for Campus Sustainability (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Energy policy. ; Energy and state. ; Biotechnology. ; Environmental education. ; Refuse and refuse disposal. ; Chemistry, Technical. ; Sustainability. ; Energy Policy, Economics and Management. ; Biotechnology. ; Environmental and Sustainability Education. ; Waste Management/Waste Technology. ; Industrial Chemistry.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2.Environmental Sustainability of Universities: Critical Review of Best Initiatives and Operational Practices -- Chapter 3. The Green Vision of Technical University of Crete’s Campus -- Chapter 4. The Construction of Green Building using Interlocking Brick System -- Chapter 5. The Feasibility of Using Palm Oil Ash in the Mix Design of Interlocking Compressed Brick -- Chapter 6. Second-generation Bioethanol: Advancement of Ethanologenic Microorganisms towards Industrial Production -- Chapter 7. Microalgae Chlorella as a campus sustainable feedstock for bioethanol production -- Chapter 8. Use of Biomass in Biocoke Production with Enhanced Calorific Values inside UTM Campus,- Chapter 9. The effect of enzyme addition on the anaerobic digestion of food waste -- Chapter 10. Anaerobic Digestion of Organic Waste in UMS Campus for Resource Recovery and Waste Reduction -- Chapter 11. Green Engineering for Waste Management System in University - A Case Study,- Chapter 12. Sustainable Waste Management in Higher Education Institutions - A case study in AC Tec,- Chapter 13. Food Waste Composting at Faculty of Engineering,- Chapter 14. Characterization of University Residential and Canteen Solid Waste for Composting and Vermicomposting Development,- Chapter 15. Sewage Treatment in Campus for Recycling Purpose: A Review,- Chapter 16. Advanced Treatment of Campus Sewage by MV/UV/O3 for Water Reclamation.
    Kurzfassung: This book highlights current efforts and research into achieving campus sustainability. The book start with Introduction followed by two chapters discusses best governance and practices in enhancing campus sustainability, while subsequent chapters elaborate on green building and bioenergy. In addition, the book discusses several initiatives regarding campus waste management including sewage recycling potential.
    Materialart: Online-Ressource
    Seiten: XVII, 259 p. 75 illus., 52 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811372605
    URL: https://doi.org/10.1007/978-981-13-7260-5
    DOI: 10.1007/978-981-13-7260-5
    DDC: 304.2
    Sprache: Englisch
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    Fish, Fishing and Community in North Korea and Neighbours : Vibrant Matter(s) (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Human geography. ; Physical geography. ; Korea History. ; Economic development. ; World politics. ; Human Geography. ; Physical Geography. ; History of Korea. ; Development Studies. ; Political History.
    Beschreibung / Inhaltsverzeichnis: Chapter One: Watery Introductions -- Chapter Two: Geographies and Histories of Fish and Fishing -- Chapter Three: Fish, Fishing Infrastructures and Fishing Knowledge (s) as Vibrant Matter -- Chapter Four: Fishing in North Korea, a History and a Geography -- Chapter Five: Gageodo, Dalian and Slavankya…Lively Matters in the Neighbourhood -- Chapter Six: Sindo, the Informal Life Politics of Fishing -- Chapter Seven: Lively Conclusions.
    Kurzfassung: This open access book explores the histories and geographies of fishing in North Korea and the surrounding nations. With the ideological and environmental history of North Korea in mind, the book examines the complex interactions between local communities, fish themselves, wider ecosystems and the politics of Pyongyang through the lens of critical geography, fisheries statistics and management science as well as North Korean and more generally Korean and East Asian studies. There is increasing global interest in North Korea, its politics, people and landscapes, and as such, this book describes encounters with North Korean fishing communities, as well as unusual moments in the field in the People’s Republic of China, the Russian Federation and the Republic of Korea (South Korea). It addresses fish, fishing infrastructure, fishing science and fishing statistics and other non-human elements of North Korean and other nations’ developmental regimes as actors and participants within them as much as humans and their technologies. The book enables readers to gain extensive insights into the aspirations and practices of fishing in North Korea and its neighbours, the navigation of difficult political and developmental situations and changing ecological realities in a time of environmental and climate crisis familiar to many across the globe.
    Materialart: Online-Ressource
    Seiten: XII, 202 p. 14 illus., 13 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811500428
    URL: https://doi.org/10.1007/978-981-15-0042-8
    DOI: 10.1007/978-981-15-0042-8
    DDC: 304.2
    Sprache: Englisch
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    The Sustainable University of the Future : Reimagining Higher Education and Research (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Sustainability. ; Technical education. ; Education, Higher. ; Education and state. ; Sustainability. ; Engineering and Technology Education. ; Higher Education. ; Educational Policy and Politics.
    Beschreibung / Inhaltsverzeichnis: Does the University Have a Future? -- Humanizing Higher Education: University of the Future -- Role of Universities in Transforming Society: Challenges and Practices -- Sustainable Development Goals (SDGs) and University Transformation -- How to Include SDGs in the Teaching Curricula -- Social Innovation in Advancing SDGs -- Gender-Related and Women Empowerment Challenges -- Knowledge-Based, Innovation, and Entrepreneurial Driven Research and Teaching -- Towards Sustainable Smart Campuses: From AI-Based Platforms for Distance Learning to Virtual Teaching -- Impact of the Industry 4.0 on the University and on Cooperative Education -- Preparing Students for Industry 4.0 -- University 4.0: Social Aspects.
    Kurzfassung: The Sustainable University of the Future discusses the rapid changes taking place within institutions of higher education—changes that have pushed universities to reconsider their traditional policies and plans. The book, which has its origins in the Qatar University Annual Research Forum and Exhibition (QUARFE) event “University of the Future” examines the many ways universities are trying to keep pace with this transformation, despite regional and international challenges. The book looks at the role of universities in meeting the United Nation's Sustainable Development Goals (SDGs), the impact of Industry 4.0, the social aspects of University 4.0, and the future of research-based universities. The need to adopt modern programs and tools is stressed, and ways to anticipate and plan for future challenges are explored. Explores the complex nature of higher education transformation; Examines the role of higher education transformation in sustainable development; Presents lessons learned from leading education experts. .
    Materialart: Online-Ressource
    Seiten: XVI, 218 p. 32 illus., 29 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031201868
    URL: https://doi.org/10.1007/978-3-031-20186-8
    DOI: 10.1007/978-3-031-20186-8
    DDC: 304.2
    Sprache: Englisch
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    Transparent Water Management Theory : Sefficiency in Sequity (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Water. ; Hydrology. ; Management. ; Pollution. ; Sustainability. ; Water. ; Management. ; Pollution.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Terminology -- Theory -- Sefficiency -- Sequity -- Applications.
    Kurzfassung: This book provides a solid foundation for a comprehensive, systemic and water-centric approach to water management. Said approach integrates two performance principles essential for sustainable water use systems, namely equity and efficiency. Further, it decreases the policy space for decision-making encountered by water managers and makes it easier to arrive at reasonable solutions because of the bounded rationality inherent in its development. By combining the distributive and aggregative principles, the approach offers a transparent and autonomous structure for gathering water data and enabling stakeholder involvement. Lastly, it employs and promotes a unifying language for all types of water use systems, e.g. urban, agricultural and industrial.
    Materialart: Online-Ressource
    Seiten: XV, 119 p. 44 illus., 3 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811562846
    Serie: Water Resources Development and Management,
    URL: https://doi.org/10.1007/978-981-15-6284-6
    DOI: 10.1007/978-981-15-6284-6
    DDC: 304.2
    Sprache: Englisch
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    Perspectives on Social LCA : Contributions from the 6th International Conference (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Industrial engineering. ; Production engineering. ; Management. ; Social choice. ; Welfare economics. ; Developmental psychology. ; Sustainability. ; Industrial and Production Engineering. ; Management. ; Social Choice and Welfare. ; Developmental Psychology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Functional Unit Definition Criteria in Life Cycle Assessment and Social Life Cycle Assessment: A Discussion (Arzoumanidis) -- Chapter 2. Towards a Taxonomy For Social Impact Pathway Indicators (Weidema) -- Chapter 3. A New Scheme For The Evaluation Of Socio-Economic Performance Of Organizations: A Well-Being Indicator Approach (di Cesare) -- Chapter 4. Structure of a Net Positive Analysis For Supply Chain Social Impacts (Norris) -- Chapter 5. Weighting and Scoring In Social Life Cycle Assessment (Telles do Carmo) -- Chapter 6. Beyond a CSR Context Towards Methodological Pluralism in S-LCA: Exploring Alternative Social Theoretical Perspectives (Baumann) -- Chapter 7. Sustainable Guar Initiative, Social Impact Characterization of an Integrated Sustainable Project (vuaillat). Chapter 8. Generation, Calculation and Interpretation of Social Impacts with the Social Analysis Of Seebalance® (Saling) -- Chapter 9. Proposal of Social Indicators to Assess The Social Performance of Waste Management Systems in Developing Countries: A Brazilian Case Study (Ibañez-Forés) -- Chapter 10. Social Assessment in the Design Phase of Automotive Component Using the Product Social Impact Assessment Method (Zanchi) -- Chapter 11. Social Life Cycle Assessment in Agricultural Systems – U.S. Corn Production as a Case Study (Frank).
    Kurzfassung: This book gives a selection of contributions from the 6th Social Life Cycle Assessment (S-LCA) Conference in Pescara, Italy. S-LCA is a social (real and potential) impact assessment method that aims to drive improvements in order to increase the value of products and services. It helps organizations to plan better, implement more effectively, and promote scale initiatives. More in general, the assessment activity also facilitates accountability and supports stakeholder communication. Consumers are greatly aware of the provenance of the goods they purchase. They have greater access to product information than ever before, also thanks to the new digital platforms. They are also empowered to make more responsible purchase decisions about what concerns sustainability aspects. Therefore the need to linger on the social aspects has been emerging recently. Although the business evolution of environmental methods and metrics has advanced significantly over the past decades, tools and metrics to estimate the social aspects of products and services are in progress. In this volume several sections provide methodological developments and tool focus, contextualizing S-LCA scientifically and explore the fields of applications. Through current development (conferences, articles, seminars and industry group publications), the method is spreading, evolving and gaining in maturity. However, it still is an evolving field, and main developments foresee, both at the level of methodology and results, interpretation and communication in order to find a path forward. S-LCA has been changing since the beginnings. From our observations as educators, researchers, practitioners, and peer reviewers in the S-LCA community, there are trends that are of importance us. .
    Materialart: Online-Ressource
    Seiten: VIII, 129 p. 37 illus., 9 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030015084
    Serie: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-01508-4
    DOI: 10.1007/978-3-030-01508-4
    DDC: 304.2
    Sprache: Englisch
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    Regenerative-Adaptive Design for Sustainable Development : A Pattern Language Approach (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Human geography. ; Urban ecology (Biology). ; Sustainable architecture. ; Sustainability. ; Human Geography. ; Urban Ecology. ; Sustainable Architecture/Green Buildings.
    Beschreibung / Inhaltsverzeichnis: Chapter1: State of the planet -- Chapter2: The challenge of a changing environment -- Chapter3: The importance of a sustainable future -- Chapter4: Sustainability, ecological systems, and climate change -- Chapter5: Beyond sustainable development: regenerative-adaptive futures -- Chapter6: Origins of advanced knowledge -- Chapter7: Interconnections between people and their natural environments -- Chapter8: A regenerative pattern language -- Chapter 9: Case study: application of the regenerative pattern language -- Chapter10: Conclusion.
    Kurzfassung: In this book, the author tests a regenerative-adaptive pattern language theory towards investigating the possibilities of a holistic, integrated design and planning method for sustainable development that incorporates the principles of regenerative design, as well as an adaptive pattern language that re-establishes our wholeness with nature, and considers the vulnerabilities of a changing landscape. The book examines an integral approach to contemporary theories of planning and design that explores the human-nature relationship patterns in social and spatial interconnections, between people and their natural environments. The interconnectedness of human and natural systems is used to scaffold possible solutions to address key environmental and sustainability issues that specifically address the need for patterns of behaviour that acknowledge the duality of ‘man and nature’. In 12 chapters, the book presents a holistic, regenerative-adaptive pattern language that encapsulates how communities can better appreciate landscape change under future climate effects, and acknowledges the importance to adapt to patterns of change of place and the environment and therefore inform the communities’ responses for sustainable development. The application of the regenerative-adaptive pattern language was tested along the Great Ocean Road region of the Victorian coast in Australia. The concluding chapters argues that for human settlements and cities to be resilient and sustainable, we must understand the interconnected patterns of human-built environments and natural systems, and how we function in a social-spatial dimension with these. The book is intended for practitioners and academic scholars with interest in sustainable development, regenerative design, pattern languages, biophilia, settlement planning, and climate change adaptation.
    Materialart: Online-Ressource
    Seiten: XXV, 247 p. 109 illus., 31 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030532345
    Serie: Sustainable Development Goals Series,
    URL: https://doi.org/10.1007/978-3-030-53234-5
    DOI: 10.1007/978-3-030-53234-5
    DDC: 304.2
    Sprache: Englisch
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  • 84
    Online-Ressource
    Online-Ressource
    SeaCities : Urban Tactics for Sea-Level Rise (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Human geography. ; Environment. ; Natural disasters. ; Environmental management. ; System theory. ; Human Geography. ; Environmental Sciences. ; Natural Hazards. ; Environmental Management. ; Complex Systems.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction -- 2. Inter-national examples of Water Hazards -- 3. Tactics and examples against sea-level rise -- 4. Application of tactics in scenarios -- 5. From risks to opportunities Outcome, outlook.
    Kurzfassung: This book presents and discusses a strategy which includes four approaches to dealing with the risk of sea-level rise and other water hazards. It also offers opportunities for cities to explore urban extensions such as marine estates, aquatic food production systems, new sea related industries, maritime transport developments, new oceanic tourist attractions, and the designation of additional coastal ecological zones. The urban interface between Sea and Cities generates, therefore, both burning issues and valuable opportunities and raises the question of whether it is possible to solve the former by exploiting the latter?
    Materialart: Online-Ressource
    Seiten: XVII, 304 p. 157 illus., 121 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811587481
    Serie: Cities Research Series,
    URL: https://doi.org/10.1007/978-981-15-8748-1
    DOI: 10.1007/978-981-15-8748-1
    DDC: 304.2
    Sprache: Englisch
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  • 85
    Online-Ressource
    Online-Ressource
    Aligning Climate Change and Sustainable Development Policies in Asia (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Environmental management. ; Bioclimatology. ; Environment. ; Sustainability. ; Environmental Management. ; Climate Change Ecology. ; Environmental Sciences.
    Beschreibung / Inhaltsverzeichnis: 1 An Introduction to Co-benefits: Core Concepts and Applications -- Part I Quantitative Modeling of Climate co-benefits and Sustainable Development -- 2 Urban Sustainable Development Index: Comparative Analysis of Low Emission Strategies in urban areas -- 3 A quantitative model for forecasting energy demand and CO2 emissions in Pakistan, towards a sustainable energy system -- 4 Multiple benefits assessment of the utilization of high-efficiency Heat Only Boilers in Ulaanbaatar, Mongolia -- Part II Co-benefits of Climate Change Mitigation Strategies -- 5 Quantifying and integrating co-benefits of renewable energy policies in South Korea -- 6 The Co-benefits of Renewable Energy Policies in Japan: Barriers and Ways Forward -- 7 Quantifying and integrating the co-benefits of solar energy in China -- Part III New Perspectives on Co-benefits -- 8 Biodiversity Co-benefits: Narrowing the Gap between Analysis and Action -- 9 Creating Social Co-benefits for Sustainable and Just Society -- 10 Enabling Japan’s low-emissions technology collaboration with Southeast Asia: The role of co-innovation and co-benefits.
    Kurzfassung: This book provides policymakers, researchers, and other interested audiences with knowledge on how to quantify and integrate and advance co-benefits in their decisions. It begins with an introductory chapter that provides an overview of the concept of co-benefits. This followed by a section that details quantitative approaches to estimate co-benefits, particularly in cities. A third section presents a series of case studies from the energy sector in Northeast and Southeast Asia. A final section focuses on new perspectives on co-benefits from linking climate change with biodiversity, social justice, and through new models of co-innovation. The book is particularly timely as many countries in Asia seek to achieve objectives in the national climate policies and the Sustainable Development Goals (SDGs). The climate emergency poses an increasingly severe threat to the health and well-being of more than a billion people in Asia. Policymakers in the region have sought to curb this threat by adopting clean energy, energy efficiency, and other sectoral policies. In some cases, these policies can bring additional benefits beyond mitigating climate change. These so-called “co-benefits” --ranging from improved air quality to better health to socioeconomic equity--could not only offset the costs of climate mitigation but also make Asia’s development more sustainable. Yet all too frequently policymakers lack the analytical methods and practical experiences to incorporate co-benefits into their decisions. This has created difficulties in aligning climate and sustainable development policies in Asia.
    Materialart: Online-Ressource
    Seiten: VIII, 185 p. 54 illus., 42 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811601354
    URL: https://doi.org/10.1007/978-981-16-0135-4
    DOI: 10.1007/978-981-16-0135-4
    DDC: 304.2
    Sprache: Englisch
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  • 86
    Online-Ressource
    Online-Ressource
    The Ecological Footprint as a Sustainability Metric : Implications for Sustainability (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Physical geography. ; Ecology . ; Energy policy. ; Energy and state. ; Environmental management. ; Environmental economics. ; Sustainability. ; Physical Geography. ; Ecology. ; Energy Policy, Economics and Management. ; Environmental Management. ; Environmental Economics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Introduction – overview and relevant background, including published (cross-disciplinary) research that provides a context and justification for the study -- Chapter 2: The Ecological Footprint – tracking the evolution of this sustainability metric -- Chapter 3: Biocapacity accounting – used to develop a context for carrying capacity set against the Ecological Footprint -- Chapter 4: Case study – national scale case consideration of Costa Rica as an example of a developing country set amid the contemporary context of sustainable development -- Chapter 5: Implications – examines the contribution for sustainable development, using the Sustainable Development Goals as a springboard for discussion -- Chapter 6: Quality Analysis – presents caveats of the methodology based on the National Footprint Accounts -- Chapter 7: Conclusion – summary of the findings and contribution of the brief, including address of path dependency and final consideration given to sustainability metrics and sustainable development.
    Kurzfassung: This book examines the Ecological Footprint and biocapacity accounting within an applied development content for Costa Rica. By doing so, it is possible to track changes as well as perhaps link these to overarching global issues, such as trade, globalization, and food security, among other emergent topics based findings stemming from this methodology. Based on a timeseries since 1961, it is possible to track cross-temporal changes of land-type categories (for crop land, grazing land, forest land, fishing ground, built-up land, and carbon) of the Ecological Footprint and biocapacity conveying whether a country is in ecological deficit and what may be contributing to such a trend.
    Materialart: Online-Ressource
    Seiten: XI, 107 p. 22 illus., 18 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030626662
    Serie: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-62666-2
    DOI: 10.1007/978-3-030-62666-2
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 87
    Online-Ressource
    Online-Ressource
    Food, Feed, Fuel, Timber or Carbon Sink? Towards Sustainable Land Use : A Consequential Life Cycle Approach (2021)
    Dordrecht :Springer Netherlands :
    Details
    Schlagwort(e): Sustainability. ; Sustainability.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction -- 2. Sustainability of Land Use: A Systems Approach -- 3. Consequential life cycle framework and methodology for the integrated sustainability impact assessment of land-use systems -- 4. Discussion and Conclusions. .
    Kurzfassung: This book provides a holistic framework for assessing the environmental and economic impacts of land-use strategies for a range of purposes, such as food, animal feed, biomass and biofuels, and timber. Using land for one purpose negates its use for any other competing purpose. Given that it is in limited supply, land needs to be optimised so that it can meet the increasing demand for crops of a growing and wealthier human population, while providing ecosystem services, such as carbon storage (i.e. climate-change mitigation). The framework is quantitative and includes various indirect effects, like indirect land-use change, and is a robust basis with which to assess global impacts from land-use decisions on climate change, ecosystem services and biodiversity. .
    Materialart: Online-Ressource
    Seiten: VIII, 125 p. 40 illus., 28 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789402420999
    Serie: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-94-024-2099-9
    DOI: 10.1007/978-94-024-2099-9
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 88
    Online-Ressource
    Online-Ressource
    Corporate Approaches to Sustainable Development : International Experiences and Insights (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Industrial management Environmental aspects. ; Environmental management. ; Sustainability. ; Corporate Environmental Management. ; Environmental Management.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. Policy Responses to COVID-19- Climate Finance and Carbon Markets -- Chapter 3. Corporate Purpose: An Emerging Approach to Corporate Sustainability -- Chapter 4. An Overview of Sustainable Finance: Linkages with the Sustainable Development Goals -- Chapter 5. The Role of Corporate Social Responsibility in Sustainable Mining: Exploring Mining Impacts of the Kansanshi Mine in Zambia -- Chapter 6. Zambia’s Mining Industry A Closer Look at the Corporate Approaches to Sustainable Development of Konkola and Mopani Copper Mines -- Chapter 7. Legislating Corporate Sustainable Development Agreements as a Corporate Social Responsibility Response for Mining Communities in Zambia A Case Study of Kabwe Lead-zinc Mine, Zambia -- Chapter 8. A Corporate Roadmap to Sustainable Resource Governance in Africa -- Chapter 9. Study of Conflicts for Water in the Sustainable Livelihoods Framework -- Chapter 10. Sustainable Communities in Resource Regions Exploring the Case of Resettlement in Colombia -- Chapter 11. Mining and Sustainable Development in Colombia -- Chapter 12. Sustainable Forest Management: Community Forestry’s contribution to build Climate Resilient Communities in Nepal -- Chapter 13. Ensuring Sustainable Post-Pandemic Tourism in Nepal: The Role of Corporate Agencies -- Chapter 14. Adaptation Strategies adopted by Indigenous Community for Sustainable Livelihood in Response to the Changing Climate: The Role of the Local Authorities and the Corporate Sector in a ca study of Sherpa Community from Lukla, Nepal -- Chapter 15. CSR Disclosure through the Principles of UN Global Compact in Bangladesh : Evidence from Emerging Markets -- Chapter 16. The Role of Managerial Efficiency, Human Capital, Research and Development in Corporate Environmental Disclosure: Insights from Bangladesh -- Chapter 17. Conclusion.
    Kurzfassung: This book aims to answer the question: how can the industry action international approaches to corporate sustainability, ultimately achieving sustainable development and overall sustainability? With this question in mind, this manuscript examines how the industry, through existing approaches to corporate sustainability, contribute to addressing conflicting demands emerging from the achievement of sustainable development in a responsible, sustainable and innovative manner. It also reviews alternative models of corporate sustainability that contribute to achieving inclusive, sustainable development globally. Chapters 2 to 4 discuss emerging approaches to corporate sustainability. Chapters 5 to 11 examine the role that the extractive industry (mining and oil) could play in the delivery of sustainable solutions for the communities and environment in selected cases, in the Americas and Africa. Lastly, the manuscript showcases international corporate sustainability and climate change practices in the forestry, agriculture, tourism and manufacturing industries within the context of Asia and The Pacific region, particularly, Nepal and Bangladesh. .
    Materialart: Online-Ressource
    Seiten: IX, 274 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811664212
    Serie: Science for Sustainable Societies,
    URL: https://doi.org/10.1007/978-981-16-6421-2
    DOI: 10.1007/978-981-16-6421-2
    DDC: 304.2
    Sprache: Englisch
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  • 89
    Online-Ressource
    Online-Ressource
    Universities, Sustainability and Society: Supporting the Implementation of the Sustainable Development Goals (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Environmental education. ; Environmental management. ; Sustainability. ; Environmental and Sustainability Education. ; Environmental Management.
    Beschreibung / Inhaltsverzeichnis: Preface -- Chapter 1. Moving towards sustainable agriculture through higher education -- Chapter 2. Balancing Sustainable Livelihoods and Conservation in the Marine environment -- Chapter 3. Linking Biodiversity and Human Health to Achieve Sustainability -- Chapter 4. Understanding scale in wicked problems of sustainable development: Who needs dedicated courses in higher education? -- Chpater 5. Presenting an interdisciplinary teaching approach to involve university students in issues of sustainable development -- Chapter 6. Methods of transdisciplinary collaboration within sustainable research and development projects -- Chapter 7. Universities as ‘global citizens’: reflections and learning from a project on female leadership for sustainable development of fishing communities in Colombia -- Chapter 8. Geography of Food Summer School: International exchange for sustainable food value chains.
    Kurzfassung: In order to yield the expected benefits, sustainability initiatives need to be undertaken by means of a close cooperation between universities on the one hand, and societal partners on the others. The principle of co-creation and co-execution of sustainability initiatives increases the value for all by mutual learning, and the sharing of expertise and resources. But pursuing sustainability initiatives with a community and societal involvement is not simple. There is a perceived need for a better understanding of how universities can interact with society, in order to support the implementation of the UN Sustainable Development Goals. This book is an attempt to address this need, by a novel approach which focuses on current potentials and challenges, across a wide range of fields and expertise. The book focuses on how the theory and practice of sustainable development interact and shows the need for a continuation of the dialogue among sustainability academics and practitioners, so as to address the issues, matters and problems at hand. The spectrum of themes addressed on this book also entails how environmental values and ethics are applied and the relationship between social, biological and cultural diversity. It also includes a broad disciplinary approach to sustainability, including education, research and case studies, and the links with human–environment relations in a sustainable development context. .
    Materialart: Online-Ressource
    Seiten: X, 560 p. 114 illus., 99 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030633998
    Serie: World Sustainability Series,
    URL: https://doi.org/10.1007/978-3-030-63399-8
    DOI: 10.1007/978-3-030-63399-8
    DDC: 304.2
    Sprache: Englisch
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  • 90
    Online-Ressource
    Online-Ressource
    East Asian Low-Carbon Community : Realizing a Sustainable Decarbonized Society from Technology and Social Systems (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Energy policy. ; Energy and state. ; Regionalism. ; Climatology. ; Asia Politics and government. ; Sustainability. ; Energy Policy, Economics and Management. ; Regionalism. ; Climate Sciences. ; Asian Politics.
    Beschreibung / Inhaltsverzeichnis: Part I. Concept and framework of the East Asian Low-Carbon Community -- Chapter 1. Climate change and low carbon society: coping with uncertainty -- Chapter 2. Climate change strategy and emission reduction roadmap for China, Japan, and South Korea -- Chapter 3. Concept and framework of the East Asian Low-Carbon Community -- Chapter 4. Modeling an East Asian Low-Carbon Community -- Part II Urban-rural Linkage for Low-Carbon Community -- Chapter 5. Realizing a local low-carbon society through urban-rural linkage -- Chapter 6. Development of a tool to optimize urban-rural linkage and a decentralized power supply -- Chapter 7. Local low-carbon society scenarios of urban-rural linkage -- Part III Technology Innovation for Low-Carbon Community -- Chapter 8. Spatial-temporal distribution of carbon capture technology according to patent data -- Chapter 9. Low-carbon technology integration -- Chapter 10. Economic assessment of Japan’s nuclear power policy -- Chapter 11. Construction of an East Asia nuclear security system -- Chapter 12. Building a global low-carbon society based on hybrid use of natural clean energy -- Part Ⅳ Social Innovation for Low-Carbon Community -- Chapter 13. Social innovation towards a low-carbon society -- Chapter 14. Achievement of nationally determined contributions (NDCs) through emissions trading in China, Japan, and South Korea -- Chapter 15. Design and analysis of a carbon emissions trading system for low-carbon development in China -- Chapter 16. An empirical analysis of international carbon transfer -- Chapter 17. Global recycling system for an East Asian low-carbon society -- Chapter 18. Building a recycling-oriented society through collaboration between urban and rural areas: sustainable domestic waste treatment “Pujiang model” -- Chapter 19. Potential for cooperation among China, Japan, and South Korea in renewable energy generation -- Chapter 20. Potential for technical cooperation between Japan and China in a third-country market -- Chapter 22. End chapter: Integration of local and global perspectives.
    Kurzfassung: This book presents new vision of regional de-carbonization with concrete scheme design and substantial quantitative demonstration from original interdisciplinary studies. It provides new horizon for not only climate change, environmental conservation but also for international cooperation and peace in East Asia. The chapters introduce diverse low carbon society principles from local to global level with best practices integrating technology evolution and social innovation. While the book is designated for academics and the ultimate goal is to facilitate international climate regime making and environmental cooperation, local government and international organizations (United Nations, World Bank, and others) officers, researchers, international NGO/NPOs, consultants, students (particularly those studying environmental policy studies or international relationships), as well as reporters will find this book useful in broadening their understanding of low-carbon development in East Asia.
    Materialart: Online-Ressource
    Seiten: XIV, 413 p. 195 illus., 130 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789813343399
    URL: https://doi.org/10.1007/978-981-33-4339-9
    DOI: 10.1007/978-981-33-4339-9
    DDC: 304.2
    Sprache: Englisch
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  • 91
    Online-Ressource
    Online-Ressource
    The Centre of City: Urban Central Structure (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Human geography. ; Regional economics. ; Spatial economics. ; Human Geography. ; Regional and Spatial Economics.
    Beschreibung / Inhaltsverzeichnis: Introduction to the Urban Centrality Structure -- Development Models of the UC Structure -- Functional Analysis of the UC Structure Hierarchy -- Spatial Layout of the UC Structure -- UC Structure Planning.
    Kurzfassung: This book presents the latest research results related to urban center and urban center. It expounds the theoretical connotation, development models, hierarchical function, and spatial layout of the urban central structure through over 200 figures and tables. In addition, it analyzes the threshold characteristics, structural hierarchy, spatial characteristics, and development rules of urban central structure through field research and quantitative researches on the major urban central structures in Asia. Meanwhile, how to solve the issue of construction and layout of urban central structure in planning and design practice is also covered. The book reveals the laws and spatial characteristics of urban central structure and provides a valuable guide both for urban designers and planners as well as researchers and students working in urban design and planning fields. It sheds new light on better understanding of the urban central structure.
    Materialart: Online-Ressource
    Seiten: XV, 609 p. 505 illus., 392 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789813366756
    URL: https://doi.org/10.1007/978-981-33-6675-6
    DOI: 10.1007/978-981-33-6675-6
    DDC: 304.2
    Sprache: Englisch
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  • 92
    Online-Ressource
    Online-Ressource
    Urban Food Deserts in Japan (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Human geography. ; Sociology. ; Nutrition. ; Food. ; Social service. ; Gerontology. ; Human Geography. ; Sociology of Food and Nutrition. ; Social Care. ; Gerontology.
    Beschreibung / Inhaltsverzeichnis: The definition of Japanese food desert issues -- The background of Japanese Food Desert Issues -- Food access and social capital -- Case Study 1 (Central Tokyo) -- Case study 2 (a prefectural government city) -- Local City -- Measures to address Food Desert Issues. .
    Kurzfassung: This book introduces the Japanese urban food desert (FD). Currently, Japan has the most rapidly aging society in the world, with a shrinking population and food desert issues in connection with the isolation of the elderly people from their families and local communities. The types of food deserts that Japan is currently facing are likely to occur in many other countries under similar circumstances in the near future. This book serves as a valuable resource for researchers and policymakers who are working on FD issues in Japan as well as in other countries. The book consists of 8 chapters, with each chapter covering a different aspect of FD, and it also includes case studies, one of which is the FD in Tokyo.
    Materialart: Online-Ressource
    Seiten: XXI, 237 p. 93 illus., 1 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811608933
    Serie: International Perspectives in Geography, AJG Library, 15
    URL: https://doi.org/10.1007/978-981-16-0893-3
    DOI: 10.1007/978-981-16-0893-3
    DDC: 304.2
    Sprache: Englisch
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  • 93
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    Online-Ressource
    Fostering Transformative Change for Sustainability in the Context of Socio-Ecological Production Landscapes and Seascapes (SEPLS) (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Landscape ecology. ; Environmental management. ; Conservation biology. ; Ecology . ; Restoration Ecology. ; Human ecology Study and teaching. ; Sustainability. ; Landscape Ecology. ; Environmental Management. ; Conservation Biology. ; Restoration Ecology. ; Environmental Studies.
    Beschreibung / Inhaltsverzeichnis: Foreword -- Preface -- Chapter 1. Introduction -- Chapter 2. Reconciling community livelihood needs and biodiversity conservation in Taita Hills forests for improved livelihoods and transformational management of the landscape -- Chapter 3. Degraded landscape transformed into foodland and woodland by village agroforestry -- Chapter 4. Long-term tracking of multiple benefits of participatory forest restoration in marginal cultural landscapes in Himalaya -- Chapter 5. Social-ecological transformation through planting mixed tree species on abandoned agricultural land in the hills of Nepal -- Chapter 6. Transformative change through ecological consumption and production of ancient wheat varieties in Tuscany, Italy -- Chapter 7. Sustainable rural development and water resources management on a hilly landscape: A case study of Gonglaoping community, Taichung, ROC (Chinese Taipei) -- Chapter 8. Transformative change in peri-urban SEPLS and green infrastructure strategies: An analysis from the local to the regional scales in Galicia (NW Spain) -- Chapter 9. Water with Integrated Local Delivery (WILD) for transformative change in socio-ecological management -- Chapter 10. Traditional landscape appropriation of Afro-descendants and collective titling in the Colombian Pacific region: lessons for a transformative change -- Chapter 11. Climate change resiliency through mangrove conservation: the case of Alitas farmers of Infanta, Philippines -- Chapter 12. Improvement of human and environmental health through waste management in Antigua and Barbuda -- Chapter 13. Synthesis: Conception, approaches and strategies for transformative.
    Kurzfassung: This open access book is a compilation of case studies that provide useful knowledge and lessons that derive from on-the-ground activities and contribute to policy recommendations, focusing on the relevance of social-ecological production landscapes and seascapes (SEPLS) to “transformative change.” The concept of “transformative change” has been gaining more attention to deal with today’s environmental and development problems, whereas both policy and scientific communities have been increasingly calling for transformative change toward sustainable society. The Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) has planned to start the so-called “assessment on transformative change” if approved by the IPBES plenary to be held in 2021. At present, the idea of transformative change, including its scope, methodologies, approaches and strategies, are yet to be clarified. By bringing together all of the different concerns and interests in the land/seascape, SEPLS approaches could provide practical and experience-based insights for understanding and gauging transformative change and identifying determinants of such change. This book explores how SEPLS management relates to the idea of transformative change to further the discussion of sustainable transitions in advancing sustainability science. The introductory chapter is followed by case study chapters offering real-world examples of transformative change as well as a synthesis chapter clarifying the relevance of the case study findings to policy and academic discussions. It will be of interest to scholars, policymakers and professionals in the fields related to sustainable development.
    Materialart: Online-Ressource
    Seiten: XII, 249 p. 78 illus., 73 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789813367616
    URL: https://doi.org/10.1007/978-981-33-6761-6
    DOI: 10.1007/978-981-33-6761-6
    DDC: 304.2
    Sprache: Englisch
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  • 94
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    Online-Ressource
    Fostering Institutional Development and Vital Change in Africa and Asia (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Economic development. ; Sustainability. ; Development Studies.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Chapter I, Sierra Leone: First impressions and experience in Africa -- Chapter II, Ghana: a model Colony and the only Sub-Sahara African Country without a civil war -- Chapter III, Madagascar: An Island Nation seeking to end its isolation and update the education system -- Chapter IV, A Peoples’ Liberation in South Africa -- Chapter V, Pakistan: leading from the topChapter VI, Afghanistan: Thought on rebuilding Afghanistan -- Chapter VII, Conclusions.
    Kurzfassung: This book looks at the question of what makes for successful change in developing countries. It focuses on people at every level in six developing countries in Africa and Asia who have helped foster positive change and development, most of which has been successful. Here, in contrast to so much academic writing on development which focuses on leadership alone, the author tries to get beyond that elite focus and highlight the people at all levels who make change possible. He examines the role and significance of these ordinary citizens and groups as well as leaders. Transformation almost always requires action and support at multiple levels from individuals, communities, and local leaders. The project analyses the cases of Afghanistan, Madagascar, Sierra Leone, Ghana, Pakistan, and South Africa. Fred M. Hayward is retired from the University of Massachusetts, Amherst, the USA where he worked on a number of development projects in Asia and Africa. He also taught at the University of Wisconsin, Madison for twenty-five years before going to work for the American Council on Education, later the Council for Higher Education Accreditation, and then carry out a number of projects is Africa and Asia funded by USAID, the Ford Foundation, Carnegie Corporation, and other funders. He has worked in more than fifteen countries in Asia and Africa.
    Materialart: Online-Ressource
    Seiten: XIII, 175 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031043642
    URL: https://doi.org/10.1007/978-3-031-04364-2
    DOI: 10.1007/978-3-031-04364-2
    DDC: 304.2
    Sprache: Englisch
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  • 95
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    Online-Ressource
    Sustainable Environment : Proceedings of NERC 2022 (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Sustainability. ; Refuse and refuse disposal. ; Environmental protection. ; Civil engineering. ; Environment. ; Sustainability. ; Waste Management/Waste Technology. ; Soil and Water Protection. ; Environmental Sciences.
    Kurzfassung: This book covers topics that addresses the global environmental issues, their challenges, and mitigation strategies for sustainable development. Some of the major challenges global environment is facing currently are global warming induced climate change because of which various extreme weather events such as flood, drought, cyclone, forest fires have increased. Industrialization with urbanization and human anthropogenic activities have caused detrimental effect on the environment resulting in environmental pollution (air and water pollution), deforestation, degradation of ecosystems, soil erosion, ground water depletion, drinking water scarcity, biodiversity loss, depletion of fossil fuels, etc. Therefore, it has become utmost necessary to switch to significant lifestyle stages along with conservation of natural resources for a sustainable environment. Sustainable environment may be defined as the practice of responsibly managing natural resources and protect overall ecosystem to support health and well-being of present and future generations. One of the major environment sustainability is the use of renewable sources of energy such as solar, wind, hydroelectric, and biomass which will reduce environmental pollution and also minimize resource misuse. At the same time, crop rotation, solid waste management, water treatment, wastewater treatment are some of the sustainable practices we must carry out for a sustainable environment. Hope, the content of the book gives an overview of recent developments, knowledge gaps related to new research areas related to environment and their future prospects.
    Materialart: Online-Ressource
    Seiten: XXX, 288 p. 174 illus., 148 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811984648
    URL: https://doi.org/10.1007/978-981-19-8464-8
    DOI: 10.1007/978-981-19-8464-8
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 96
    Online-Ressource
    Online-Ressource
    The Future of the UN Sustainable Development Goals : Business Perspectives for Global Development in 2030 (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Industrial management Environmental aspects. ; Development economics. ; Business ethics. ; Management. ; Economic development. ; Sustainability. ; Corporate Environmental Management. ; Development Economics. ; Business Ethics. ; Management. ; Development Studies.
    Beschreibung / Inhaltsverzeichnis: Business Perspectives of Sustainable Development Goals 2030: An Introduction -- Part I: African Business Perspectives of Agenda 2030 -- Part II: European Business Perspectives of Agenda 2030 -- Part III: Asian Business Perspectves of Agenda 2030.
    Kurzfassung: This book provides a business-oriented analysis of the United Nations (UN) Sustainable Development Goals (SDG). In order to assess their impact on businesses and corporations, the book addresses all 17 goals and a broad range of industries. Gathering contributions from Africa, Europe and Asia, it presents both critical reviews and case studies. In turn, the book seeks to predict likely developments during the next decade. To do so, it examines evidence from today’s business world and how companies and corporations have been adopting the SDGs since their release. In this regard, it discusses the changes that will be required and how the agenda will affect the continent’s development path. An underlying theme throughout the book is the role of monetary value and investment for sustainable development: whether through financing, enhanced turnaround resulting from a more educated population, or more socially innovative entrepreneurs.
    Materialart: Online-Ressource
    Seiten: XXVIII, 404 p. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030211547
    Serie: CSR, Sustainability, Ethics & Governance,
    URL: https://doi.org/10.1007/978-3-030-21154-7
    DOI: 10.1007/978-3-030-21154-7
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 97
    Online-Ressource
    Online-Ressource
    Sustainable Development of Water and Environment : Proceedings of the ICSDWE2021 (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Sustainability. ; Environmental management. ; Environmental protection. ; Civil engineering. ; Environmental monitoring. ; Refuse and refuse disposal. ; Sustainability. ; Environmental Management. ; Soil and Water Protection. ; Environmental Monitoring. ; Waste Management/Waste Technology.
    Beschreibung / Inhaltsverzeichnis: Solar Thermal Energy Production in DSF Applied in the Human Comfort Improvements -- Hydraulics Geometry Analysis of UPNM Channel -- Productivity Enhancement of Solar Still Distillation System Using Immersion-Type Water Heater -- Stability Analysis of a Man-made Slope: A Case Study on the UPNM Campus, Sg Besi, Kuala Lumpur -- Comparison of the Full-Scale Municipal Wastewater Treatment Plant Designs Consisting of Modified Bardenpho Process with and without Membrane Bioreactor for Nutrient Removal: Cost Analysis -- Numerical Evaluation of the Temperature Distribution in a Tree Trunk in a Forest Fire Environment -- Analysis of Soluble Organic Polar Fractions from Sea Salt by GC-MS -- Spatial-temporal variationan alysis on ecosystem service values in a typical inland river basin, northwest China -- Collaboration Mapping in Sustainable Development: A case study from haze in Chiang Mai -- Effect of Current and Electrodes Area to Color Removal Efficiency and Energy Consumption by Electrocoagulation Process -- Key Technology and Economic Analysis of Using Fujiang River Water as the Cooling and Heating Sources for Air Conditioning System -- Statistical analysis of water and sediment research in Heilongjiang River Basin -- Analytical approach for sustainable multi-objective management of sediment-algae dynamics -- Integration of experimental and numerical methods to investigate the effect of hydraulic retention time on ultrafiltration membrane fouling -- Study on the Model of Construction Safety Risk Evaluation Coupling Multiple Factors in Navigable Waters -- Distribution Characteristics of Plastic Particles in Coastal and Beach of Hsinchu, Taiwan.
    Kurzfassung: This book addresses the improvement and dissemination of knowledge on methods, policies and technologies for increasing the sustainability of development by de-coupling growth from natural resources and replacing them with knowledge-based economy, taking into account its economic, environmental and social pillars, as well as methods for assessing and measuring sustainability of development, regarding water and environment. This book gathers scholar and experts in related fields. All attendees from a vast range of companies, universities and government institutions acquire advanced technical knowledge and are introduced to new fields through discussions that focus on their own specialties as well as a variety of interdisciplinary areas. The authors hope most of scholars can find what they really need in this book.
    Materialart: Online-Ressource
    Seiten: X, 343 p. 136 illus., 90 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030752781
    Serie: Environmental Science and Engineering,
    URL: https://doi.org/10.1007/978-3-030-75278-1
    DOI: 10.1007/978-3-030-75278-1
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 98
    Online-Ressource
    Online-Ressource
    Ethnic Enclaves in Contemporary Japan (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Human geography. ; Race. ; Demography. ; Population. ; Sociology. ; Human Geography. ; Race and Ethnicity Studies. ; Population and Demography. ; Sociology.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Overview of Ethnic Enclaves as Example Cases -- Chinese Enclaves: Formation of New Chinatowns by Chinese Newcomers -- The Contrasting Enclaves between Korean Oldcomers and Newcomers -- Filipino Enclaves as Products of Migration Industry: Cases in a Big City’s Downtown and a Port City’s Coastal Area -- Brazilian Residents as Persistent Repeaters and Their Enclaves -- Turkish Residents and Marital Assimilation -- Conclusion. .
    Kurzfassung: This book is the first work to comprehensively investigate the enclaves of non-Japanese residents in Japan. In a comparative study, it convincingly examines eight enclaves of five nationalities (Chinese, Korean, Filipino, Brazilian and Turkish) in twelve municipalities. Japan now leads in terms of depopulation in countries affiliated with the Organisation for Economic Co-operation and Development (OECD). The fact that the country has been supplementing the decreased number of Japanese nationals with an increase in migrants, who form enclaves, has attracted great attention. The temporal development and status quo of such enclaves are important concerns of researchers, policymakers and the general public. This publication is the result of joint studies by geographers and sociologists and contributes to a more detailed understanding of these topics. It thus represents a valuable achievement in the study of the segregation and enclave formation of minority nationalities. The empirical validity of existing explanatory frameworks, such as spatial assimilation and heterolocalism, is also discussed in a Japanese context.
    Materialart: Online-Ressource
    Seiten: XV, 189 p. 64 illus., 57 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789813369955
    Serie: International Perspectives in Geography, AJG Library, 14
    URL: https://doi.org/10.1007/978-981-33-6995-5
    DOI: 10.1007/978-981-33-6995-5
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 99
    Online-Ressource
    Online-Ressource
    Revitalising Rural Communities (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Environmental sciences Social aspects. ; Human geography. ; Cultural geography. ; Cultural property. ; Sociology, Urban. ; Environmental Social Sciences. ; Social and Cultural Geography. ; Cultural Heritage. ; Urban Sociology.
    Beschreibung / Inhaltsverzeichnis: Chapter 01 Rural Sustainability: challenges and opportunities -- Chapter 02 Case study: Rural revitalization in Hong Kong -- Chapter 03 Rural Sustainability: six core dimensions -- Chapter 04 Conclusion and the future of rural communities.
    Kurzfassung: This book highlights the challenges and opportunities of (re)constructing a sustainable rural community on the outskirts of the urban community. Based on knowledge and experience accumulated through implementing a rural revitalisation project in Hong Kong since 2013, the book provides an in-depth analysis of a case study along with related concepts from the literature. In particular, the concept of rural resilience is broken down and used to examine how communities at the urban-rural interface can leverage their position and connections to (re)create vibrant sustainable communities. The revitalisation project was showcased in the databases of the United Nations Development Programme (UNDP)’s Equator Initiative and the International Partnership for the Satoyama Initiative (IPSI) as well as achieving Special Recognition for Sustainable Development in the UNESCO Asia-Pacific Awards for Cultural Heritage Conservation in 2020. This book teases out the key issues in the process of revitalising a rural community in the peri-urban context and examines the complexities embedded in each issue and how they can be addressed in the quest for rural sustainability.
    Materialart: Online-Ressource
    Seiten: IX, 94 p. 5 illus., 3 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811658242
    Serie: SpringerBriefs on Case Studies of Sustainable Development,
    URL: https://doi.org/10.1007/978-981-16-5824-2
    DOI: 10.1007/978-981-16-5824-2
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 100
    Online-Ressource
    Online-Ressource
    Green Technologies and Infrastructure to Enhance Urban Ecosystem Services : Proceedings of the Smart and Sustainable Cities Conference 2018 (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Human geography. ; Urban ecology (Biology). ; Sustainability. ; Soil science. ; Physical geography. ; Human Geography. ; Urban Ecology. ; Sustainability. ; Soil Science. ; Physical Geography.
    Kurzfassung: These proceedings of the Smart and Sustainable Cities Conference (SSC) in Moscow from May 23 to 26, 2018 addresses important questions regarding the global trend of urbanization. What are the environmental consequences of megacities’ expansion? What smart solutions can make life in cities safe, comfortable and environmentally friendly? It is projected that 70% of the global population will live in cities by 2050, and as such the book describes how this rapid urbanization will alter the face of the world. Focusing on solutions for the environmental problems of modern megapolises, it discusses advanced approaches and smart technologies to monitor, model and assess the environmental consequences and risks. The contributors present examples of successful sustainable urban development, including management and design of green infrastructure, waste management, run-off purification and remediation of urban soils. The SSC conference and its proceedings offer a valuable contribution to sustainable urban development, and are of interest to the scientific and research community, municipal services, environmental protection agencies, landscape architects, civil engineers, policy makers and other stakeholders in urban management and greenery.
    Materialart: Online-Ressource
    Seiten: XIII, 280 p. 117 illus., 97 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030160913
    Serie: Springer Geography,
    URL: https://doi.org/10.1007/978-3-030-16091-3
    DOI: 10.1007/978-3-030-16091-3
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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