Keywords:
Pharmacology.
;
Pharmacology.
Description / Table of Contents:
From the contents. Preface.-Part I: Molecular aspects of KOR -- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals -- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.
Abstract:
This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Type of Medium:
Online Resource
Pages:
XI, 577 p. 100 illus., 30 illus. in color.
,
online resource.
Edition:
1st ed. 2022.
ISBN:
9783030890742
Series Statement:
Handbook of Experimental Pharmacology, 271
URL:
https://doi.org/10.1007/978-3-030-89074-2
DOI:
10.1007/978-3-030-89074-2
DDC:
615
Language:
English
