Publication Date:
1999-01-23
Description:
The plant hormone abscisic acid (ABA) regulates potassium and chloride ion channels at the plasma membrane of guard cells, leading to stomatal closure that reduces transpirational water loss from the leaf. The tobacco Nt-SYR1 gene encodes a syntaxin that is associated with the plasma membrane. Syntaxins and related SNARE proteins aid intracellular vesicle trafficking, fusion, and secretion. Disrupting Nt-Syr1 function by cleavage with Clostridium botulinum type C toxin or competition with a soluble fragment of Nt-Syr1 prevents potassium and chloride ion channel response to ABA in guard cells and implicates Nt-Syr1 in an ABA-signaling cascade.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Leyman, B -- Geelen, D -- Quintero, F J -- Blatt, M R -- New York, N.Y. -- Science. 1999 Jan 22;283(5401):537-40.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Plant Physiology and Biophysics, University of London, Wye College, Wye, Kent TN25 5AH, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9915701" target="_blank"〉PubMed〈/a〉
Keywords:
Abscisic Acid/*pharmacology
;
Amino Acid Sequence
;
Animals
;
Botulinum Toxins/metabolism
;
Cell Membrane/physiology
;
Chloride Channels/*physiology
;
Genes, Plant
;
Genetic Complementation Test
;
Ion Channel Gating/drug effects
;
Membrane Proteins/chemistry/genetics/*physiology
;
Molecular Sequence Data
;
Oocytes
;
Patch-Clamp Techniques
;
Plant Growth Regulators/*pharmacology
;
Plant Leaves/*physiology
;
*Plants, Toxic
;
Potassium Channels/*physiology
;
Qa-SNARE Proteins
;
Saccharomyces cerevisiae/genetics/growth & development
;
Signal Transduction
;
Tobacco/genetics/*physiology
;
Xenopus
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
