Publication Date:
1979-08-17
Description:
Microfluorometric measurements of cerebral cortical mitochondrial respiration in vivo are obscured by hemodynamic and oximetric artifacts. Isosbestic fluorometry provides appropriate correction for these vascular phenomena and permits simultaneous evaluation of mitochondrial nicotinamide adenine dinucleotide redox state, microcirculatory volume, and hemoglobin oxygenation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kramer, R S -- Pearlstein, R D -- New York, N.Y. -- Science. 1979 Aug 17;205(4407):693-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/223243" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
*Brain Chemistry
;
Cerebral Cortex/*analysis
;
Dogs
;
Fluorometry/instrumentation/*methods
;
Hemoglobins/analysis
;
Hypoxia, Brain/metabolism
;
Mitochondria/metabolism
;
NAD/*analysis/metabolism
;
Oxidation-Reduction
;
Oxygen/blood
;
Rhodamines
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
