Publication Date:
2015-01-24
Description:
The root meristem consists of populations of distal and proximal stem cells and an organizing center known as the quiescent center. During embryogenesis, initiation of the root meristem occurs when an asymmetric cell division of the hypophysis forms the distal stem cells and quiescent center. We have identified NO TRANSMITTING TRACT (NTT) and two closely related paralogs as being required for the initiation of the root meristem. All three genes are expressed in the hypophysis, and their expression is dependent on the auxin-signaling pathway. Expression of these genes is necessary for distal stem cell fate within the root meristem, whereas misexpression is sufficient to transform other stem cell populations to a distal stem cell fate in both the embryo and mature roots.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Crawford, Brian C W -- Sewell, Jared -- Golembeski, Greg -- Roshan, Carmel -- Long, Jeff A -- Yanofsky, Martin F -- 5 R01 GM072764/GM/NIGMS NIH HHS/ -- R01 GM072764/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2015 Feb 6;347(6222):655-9. doi: 10.1126/science.aaa0196. Epub 2015 Jan 22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA. ; Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA. ; Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA. marty@ucsd.edu jeffalong@ucla.edu. ; Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA. marty@ucsd.edu jeffalong@ucla.edu.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25612610" target="_blank"〉PubMed〈/a〉
Keywords:
Arabidopsis/embryology/genetics
;
Arabidopsis Proteins/genetics/*physiology
;
*Gene Expression Regulation, Developmental
;
*Gene Expression Regulation, Plant
;
Indoleacetic Acids/pharmacology
;
Meristem/cytology/*embryology
;
Mutation
;
Plant Development/*genetics
;
Stem Cells/cytology/drug effects/*physiology
;
Transcription Factors/genetics/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
