Publication Date:
2014-03-01
Description:
Auxin-binding protein 1 (ABP1) was discovered nearly 40 years ago and was shown to be essential for plant development and morphogenesis, but its mode of action remains unclear. Here, we report that the plasma membrane-localized transmembrane kinase (TMK) receptor-like kinases interact with ABP1 and transduce auxin signal to activate plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading to changes in the cytoskeleton and the shape of leaf pavement cells in Arabidopsis. The interaction between ABP1 and TMK at the cell surface is induced by auxin and requires ABP1 sensing of auxin. These findings show that TMK proteins and ABP1 form a cell surface auxin perception complex that activates ROP signaling pathways, regulating nontranscriptional cytoplasmic responses and associated fundamental processes.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166562/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166562/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Xu, Tongda -- Dai, Ning -- Chen, Jisheng -- Nagawa, Shingo -- Cao, Min -- Li, Hongjiang -- Zhou, Zimin -- Chen, Xu -- De Rycke, Riet -- Rakusova, Hana -- Wang, Wuyi -- Jones, Alan M -- Friml, Jiri -- Patterson, Sara E -- Bleecker, Anthony B -- Yang, Zhenbiao -- GM065989/GM/NIGMS NIH HHS/ -- GM081451/GM/NIGMS NIH HHS/ -- R01 GM081451/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2014 Feb 28;343(6174):1025-8. doi: 10.1126/science.1245125.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Plant Cell Biology, Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24578577" target="_blank"〉PubMed〈/a〉
Keywords:
Arabidopsis/*enzymology/genetics
;
Cell Membrane/*enzymology
;
Indoleacetic Acids/*metabolism
;
Plant Leaves/enzymology/genetics
;
Plant Proteins/*metabolism
;
Protein Kinases/genetics/*metabolism
;
Receptors, Cell Surface/*metabolism
;
Signal Transduction
;
rho GTP-Binding Proteins/*metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
