Publication Date:
2008-10-25
Description:
During the development of multicellular organisms, organogenesis and pattern formation depend on formative divisions to specify and maintain pools of stem cells. In higher plants, these activities are essential to shape the final root architecture because the functioning of root apical meristems and the de novo formation of lateral roots entirely rely on it. We used transcript profiling on sorted pericycle cells undergoing lateral root initiation to identify the receptor-like kinase ACR4 of Arabidopsis as a key factor both in promoting formative cell divisions in the pericycle and in constraining the number of these divisions once organogenesis has been started. In the root tip meristem, ACR4 shows a similar action by controlling cell proliferation activity in the columella cell lineage. Thus, ACR4 function reveals a common mechanism of formative cell division control in the main root tip meristem and during lateral root initiation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉De Smet, Ive -- Vassileva, Valya -- De Rybel, Bert -- Levesque, Mitchell P -- Grunewald, Wim -- Van Damme, Daniel -- Van Noorden, Giel -- Naudts, Mirande -- Van Isterdael, Gert -- De Clercq, Rebecca -- Wang, Jean Y -- Meuli, Nicholas -- Vanneste, Steffen -- Friml, Jiri -- Hilson, Pierre -- Jurgens, Gerd -- Ingram, Gwyneth C -- Inze, Dirk -- Benfey, Philip N -- Beeckman, Tom -- New York, N.Y. -- Science. 2008 Oct 24;322(5901):594-7. doi: 10.1126/science.1160158.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB), B-9052 Ghent, Belgium.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18948541" target="_blank"〉PubMed〈/a〉
Keywords:
Arabidopsis/*cytology/*enzymology/genetics/growth & development
;
Arabidopsis Proteins/*genetics/*metabolism
;
*Cell Division
;
Cell Lineage
;
Gene Expression Profiling
;
Gene Expression Regulation, Plant
;
Genes, Plant
;
Meristem/*cytology/enzymology/growth & development
;
Mutation
;
Plant Roots/*cytology/enzymology/growth & development
;
Protein-Serine-Threonine Kinases
;
Receptors, Cell Surface/*genetics/*metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
