Publication Date:
2015-04-12
Description:
Article Long non-coding RNAs or lincRNAs identified in embryonic stem (ES) cells have been shown to regulate ES cell states; however, how these lincRNAs are regulated remains unclear. Here the authors show that the transcriptional coactivator Pontin regulates the expression of lincRNAs involved in ES cell maintenance in an Oct4-dependent manner. Nature Communications doi: 10.1038/ncomms7810 Authors: Kyungjin Boo, Jinhyuk Bhin, Yoon Jeon, Joomyung Kim, Hi-Jai R. Shin, Jong-Eun Park, Kyeongkyu Kim, Chang Rok Kim, Hyonchol Jang, In-Hoo Kim, V. Narry Kim, Daehee Hwang, Ho Lee, Sung Hee Baek
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics