Publikationsdatum:
2015-04-12
Beschreibung:
Article Long non-coding RNAs or lincRNAs identified in embryonic stem (ES) cells have been shown to regulate ES cell states; however, how these lincRNAs are regulated remains unclear. Here the authors show that the transcriptional coactivator Pontin regulates the expression of lincRNAs involved in ES cell maintenance in an Oct4-dependent manner. Nature Communications doi: 10.1038/ncomms7810 Authors: Kyungjin Boo, Jinhyuk Bhin, Yoon Jeon, Joomyung Kim, Hi-Jai R. Shin, Jong-Eun Park, Kyeongkyu Kim, Chang Rok Kim, Hyonchol Jang, In-Hoo Kim, V. Narry Kim, Daehee Hwang, Ho Lee, Sung Hee Baek
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik