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Hyper-recombination in dam mutants of Escherichia coli K-12 (1976)

Marinus, M. G. ; Konrad, E. Bruce

Springer

Molecular genetics and genomics 149 (1976), S. 273-277

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ISSN: 1617-4623

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Summary F-prime heterogenotes of dam-3 bacteria segregate F-prime homogenotes at a frequency 30–200 times higher than the isogenic dam + strain. A hyperrecombination mutant which shows increased recombination between chromosomal duplications was characterized as a dam mutant. The dam-3 allele causes a reduction in linkage of proximal unselected markers in transconjugants and increases the recombination frequency between a pair of closely linked markers. It is concluded that dam mutations confer a hyperrecombination phenotype to the cell.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00268528

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