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Effects of cycloheximide on cellular elongation in aManduca sexta cell line (1981)

Oberlander, H. ; Leach, C. E. ; Lynn, D. E.

Springer

Development genes and evolution 190 (1981), S. 60-61

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ISSN: 1432-041X

Keywords: Cycloheximide ; Manduca sexta ; 20-hydroxy-ecdysone, insect tissue culture

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Summary A clone (GV1) of the CHIManduca sexta cell line responds to 20-hydroxy-ecdysone by changing cellular shape from an epithelial-like form to an elongated fibroblast-like form. We have determined that this morphological response to hormone is prevented by treatment with cycloheximide. The inhibition of the elongation response by cycloheximide may relate to a requirement for the synthesis of specific proteins that play a role in the formation of cytoskeletal structure.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00868706

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