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Drosophila alcohol dehydrogenase: Developmental studies on cryptic variant lines (1981)

Miglani, Gurbachan S. ; Ampy, Franklin R.

Springer

Biochemical genetics 19 (1981), S. 947-954

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ISSN: 1573-4927

Keywords: alcohol dehydrogenase ; Drosophila ; cryptic variants

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract Thirty-five cryptic variant lines were used to examine the mechanisms involved in genetic modulation of alcohol metabolism in Drosophila. Late third-instar larval, preemergence pupal, and adult stages cultured at 18 and 28 C were examined. Spectrophotometric analyses for native alcohol dehydrogenase (ADH) activity and residual ADH activity after treatment with guanidine hydrochloride and heat were performed. Differential response of cryptic variants to treatment with the denaturants during development suggested that this variation may have an adaptive significance.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00504259

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