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Purification of thrombospondin from human platelets (1994)

Roberts, David D. ; Cashel, JoAnne ; Guo, Neng-hua

Springer

Methods in cell science 16 (1994), S. 217-222

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ISSN: 1573-0603

Keywords: α-granules ; Heparin-affinity ; Platelets ; Thrombospondin

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Summary Thrombospondins are a rapidly growing family of adhesive proteins that have diverse activities to modulate cellular growth, motility, and gene expression. Thrombospondin-1 (TSP) was the first identified member of this family and is the major form of thrombospondin in human platelets. A method is described to prepare TSP from human platelets in biologically active form with minimal degradation or contamination with other platelet proteins.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01540654

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