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Effects of puromycin on rat embryos in vitro (1987)

Flynn, T. J. ; Friedman, L. ; Black, T. N.

Springer

Cellular and molecular life sciences 43 (1987), S. 433-435

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ISSN: 1420-9071

Keywords: Rat embryo ; in vitro ; puromycin ; microbial toxin ; teratogenicity ; lipids

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Somite-staged rat embryos were exposed to varying concentrations of puromycin for 48 h in vitro. Medium concentrations below 0.92 μM had no significant effects, while concentrations above 1.84 μM were lethal. Between these extremes, there were concentration dependent increases in the incidence of malformations in a close relationship to growth retardation.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01940442

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