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Action inhibitrice du thiouracil sur la carotine (1947)

Canadell, J. M. ; Valdecasas, F. G.

Springer

Cellular and molecular life sciences 3 (1947), S. 35-36

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ISSN: 1420-9071

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary White rats submitted to a purified diet without vitamin A develop normally with carotene. When these animals are treated with thiouracil they show trophic alterations analogous to these observed in animals submitted to a diet without vitamine or provitamine A. These disturbances are cured immediately when vitamine A or powdered thyroids are given; on the other hand they continue when the dose of carotene is augmented. Iodine too exercises a protective and curative effect with an antagonistic action to thiouracil. The authors interpret these disturbances as due to an inhibition of the carotinase produced by thiouracil.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02155122

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