ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
2-(Alkylamino)-4-(dichloromethyl)quinolines from (Trichlorovinyl)ketene N-Arylimines and Aliphatic AminesOn treatment of the N-alkylketene imine 2a with morpholine in THF, the amino substituted butenimine 5a is formed probably via 3a. When, however, the N-arylketene imines 2b and c, generated in situ from the amides 4b and c, react with secondary aliphatic amines or tert-butylamine the quinolines 6a-c are produced. The structure of 6b is confirmed by the 13C NMR spectrum. The formation of 5a and quinolines 6 from 2 may be considered as an evidence for compounds of type 3 and 5 as intermediates in the formation of 7 from 1 or 2 with primary amines (see preceding paper).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19821150729
