Call number:
9789811084171 (e-book)
Description / Table of Contents:
This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. Thebook provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.
Type of Medium:
12
Pages:
1 Online-Ressource (xiv, 360 Seiten)
,
Illustrationen
ISBN:
9789811084171
,
978-981-10-8417-1
URL:
Ebook (access only within the AWI network)
DOI:
10.1007/978-981-10-8417-1
Language:
English
Note:
Contents
1 Omics: A Holistic Approach in Cancer Treatment / Madhumati Bora and Pratibha Parihar
2 Plant miRNAs and Phytomolecules As Anticancer Therapeutics / Nikita Shukla, Virendra Shukla, and Sangeeta Saxena
3 Potential of Herbal Medicines in Colorectal Carcinoma and Their Mechanism of Action / Navina Panneerselvan, Rajeswari Ravindran, Palanisamy Arulselvan, and Ravindran Jaganathan
4 Elucidation of Mechanisms of Anticancer Plant Compounds Against the Tumor Cells / Radhakrishnan Narayanaswamy and Mallappa Kumara Swamy
5 Computational Approach Towards Exploring Interaction of Target Protein-Phytocompounds in Drug Development for Breast Cancer / Asita Elengoe and Salehhuddin Hamdan
6 Anticancer Potential of Andrographolide, a Diterpenoid Lactone from Andrographis paniculata: A Nature’s Treasure for Chemoprevention and Therapeutics / Imran Khan, Mohd Aslam Yusuf, Irfan Ahmad Ansari, and Mohd Sayeed Akhtar
7 Anticancer Activity of Herbal Medicine: Mechanism of Action / Nand Kumar Singh, Alok Kumar Yadav, Preeti Sirohi, Manjoo Rani, Saurabh Saraswat, Manish Pratap Singh, Ashutosh Mani, and Sameer Srivastava
8 Metabolomic Study of Chemo-preventive Phytochemicals and Their Therapeutic Prospects / Nibir Ranjan Parasar, Channakeshavaiah Chikkaputtaiah, Mohan Lal, and Mohd Sayeed Akhtar
9 CADD Studies Applied to Secondary Metabolites in the Anticancer Drug Research / Luciana Scotti, Nagendra Sastry Yarla, Francisco J. B. Mendonça Filho, José M. Barbosa Filho, Marcelo S. da Silva, Josean F. Tavares, and Marcus Tullius Scotti
10 Anticancerous Plant Compounds Affecting the Power House of Cancerous Cells: A Possible Herbal Mitocan / Shalini Mani, Nancy Taneja, Sweekriti Jain, and Manisha Singh
11 Phytoestrogens as a Natural Source for the Possible Colon Cancer Treatment / Suresh Challa, Rajanna Ajumeera, and Naresh Venna
12 Bioinformatics Approaches for Genomics and Post Genomics Applications of Anticancer Plants / Avni Mehta and Yasha Hasija
13 Fruits of Rosaceae Family as a Source of Anticancer Compounds and Molecular Innovations / Muhammad Sameeullah, Muttalip Gündoğdu, İhsan Canan, Turan Karadeniz, Muhammad Aasim, and Khalid Mahmood Khawar
14 Mechanism of Action of Anticancer Herbal Medicines / Mohd Gulfishan, Muhammad Afzal, Imran Kazmi, Anwarulabedin Mohsin Quazi, Tariq Ahmad Bhat,
and Ajmat Jahan
