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  • 1
    Call number: 9789811084171 (e-book)
    Description / Table of Contents: This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. Thebook provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.
    Type of Medium: 12
    Pages: 1 Online-Ressource (xiv, 360 Seiten) , Illustrationen
    ISBN: 9789811084171 , 978-981-10-8417-1
    Language: English
    Note: Contents 1 Omics: A Holistic Approach in Cancer Treatment / Madhumati Bora and Pratibha Parihar 2 Plant miRNAs and Phytomolecules As Anticancer Therapeutics / Nikita Shukla, Virendra Shukla, and Sangeeta Saxena 3 Potential of Herbal Medicines in Colorectal Carcinoma and Their Mechanism of Action / Navina Panneerselvan, Rajeswari Ravindran, Palanisamy Arulselvan, and Ravindran Jaganathan 4 Elucidation of Mechanisms of Anticancer Plant Compounds Against the Tumor Cells / Radhakrishnan Narayanaswamy and Mallappa Kumara Swamy 5 Computational Approach Towards Exploring Interaction of Target Protein-Phytocompounds in Drug Development for Breast Cancer / Asita Elengoe and Salehhuddin Hamdan 6 Anticancer Potential of Andrographolide, a Diterpenoid Lactone from Andrographis paniculata: A Nature’s Treasure for Chemoprevention and Therapeutics / Imran Khan, Mohd Aslam Yusuf, Irfan Ahmad Ansari, and Mohd Sayeed Akhtar 7 Anticancer Activity of Herbal Medicine: Mechanism of Action / Nand Kumar Singh, Alok Kumar Yadav, Preeti Sirohi, Manjoo Rani, Saurabh Saraswat, Manish Pratap Singh, Ashutosh Mani, and Sameer Srivastava 8 Metabolomic Study of Chemo-preventive Phytochemicals and Their Therapeutic Prospects / Nibir Ranjan Parasar, Channakeshavaiah Chikkaputtaiah, Mohan Lal, and Mohd Sayeed Akhtar 9 CADD Studies Applied to Secondary Metabolites in the Anticancer Drug Research / Luciana Scotti, Nagendra Sastry Yarla, Francisco J. B. Mendonça Filho, José M. Barbosa Filho, Marcelo S. da Silva, Josean F. Tavares, and Marcus Tullius Scotti 10 Anticancerous Plant Compounds Affecting the Power House of Cancerous Cells: A Possible Herbal Mitocan / Shalini Mani, Nancy Taneja, Sweekriti Jain, and Manisha Singh 11 Phytoestrogens as a Natural Source for the Possible Colon Cancer Treatment / Suresh Challa, Rajanna Ajumeera, and Naresh Venna 12 Bioinformatics Approaches for Genomics and Post Genomics Applications of Anticancer Plants / Avni Mehta and Yasha Hasija 13 Fruits of Rosaceae Family as a Source of Anticancer Compounds and Molecular Innovations / Muhammad Sameeullah, Muttalip Gündoğdu, İhsan Canan, Turan Karadeniz, Muhammad Aasim, and Khalid Mahmood Khawar 14 Mechanism of Action of Anticancer Herbal Medicines / Mohd Gulfishan, Muhammad Afzal, Imran Kazmi, Anwarulabedin Mohsin Quazi, Tariq Ahmad Bhat, and Ajmat Jahan
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  • 2
    Call number: 9789811085482 (e-book)
    Description / Table of Contents: Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.
    Type of Medium: 12
    Pages: 1 Online-Ressource (viiI, 582 Seiten) , Illustrationen
    ISBN: 9789811085482 , 978-981-10-8548-2
    Language: English
    Note: Contents 1 Current Practices and Awareness of Anticancer Plants in the Traditional Healthcare System / Paola De Cicco, Elisabetta Panza, Chiara Armogida, Giuseppe Ercolano, Giuseppe Cirino, and Angela Ianaro 2 Phytochemical and Biological Properties of Lippia gracilis / Valéria Regina de Souza Moraes, Paulo Cesar de Lima Nogueira, Emmanoel Vilaça Costa, Luciano de Souza Santos, Valdenizia Rodrigues Silva, Larissa Mendes Bomfim, and Daniel Pereira Bezerra 3 Use of Indian Indigenous Fruits in Cancer Prevention and Treatment / Manjeshwar Shrinath Baliga, Suresh Rao, Pratima Rao, Krishnaprasad, Sanath Kumar Hegde, Kandel Codi Jalaluddin Akbar, Soniya Abraham, Thomas George, and Princy Louis Palatty 4 Potentiality of Anticancer Plant-Derived Compounds of North-East India / Mohan Lal, Nibir Ranjan Parasar, Anil Kumar Singh, and Mohd Sayeed Akhtar 5 Plant-Derived Compounds in Cancer Therapy: Traditions of Past and Drugs of Future / Bee Ling Tan and Mohd Esa Norhaizan 6 Anticancer Plant Molecules for the Improvement of Immune System / Om Prakash, Pratibha Preeti Maurya, and Ajeet 7 Fermented Food-Derived Bioactive Compounds with Anticarcinogenic Properties: Fermented Royal Jelly As a Novel Source for Compounds with Health Benefits / Muhammad Hussein Alu’datt, Taha Rababah, Hafiz Arbab Sakandar, Muhammad Imran, Neveen Mustafa, Mohammad Noor Alhamad, Nizar Mhaidat, Stan Kubow, Carole Tranchant, Abdel Rahman Al-Tawaha, and Wafa Ayadi 8 Mass Spectrometry-Based Techniques for the Assessment of Pharmacological Responses of Ayurvedic Drugs / Amey Shirolkar, Manasi Malgaonkar, Amit Pawase, Sudesh Gaidhani, and Sharad Pawar 9 Assessment of Anticancer Properties of Betelvine / Deepali Shukla, Jayendra Johri, Suchi Srivastava, and Poonam C. Singh 10 Analysis of Patents Filed for the Herbal Therapeutics Against Cancer / Pooja Rawat and Pawan Kumar Singh 11 Appraisal of Medicinal Plants with Anticancer Properties in South America / Alírica Isabel Suárez and Katiuska Chávez 12 Scientific Validation of the Usefulness of Withania somnifera Dunal in the Prevention and Treatment of Cancer / G. S. Pavan Kumar Achar, B. T. Prabhakar, Suresh Rao, Thomas George, Soniya Abraham, Nicole Sequeira, and Manjeshwar Shrinath Baliga 13 Anticancer Potential of Mangrove Plants: Neglected Plant Species of the Marine Ecosystem / Rout George Kerry, Pratima Pradhan, Gitishree Das, Sushanto Gouda, Mallappa Kumara Swamy, and Jayanta Kumar Patra 14 Piper betle Linn. in Cancer: Past, Present, and Future / Avinash Kundadka Kudva, Suresh Rao, Pratima Rao, Romith Periera, Ganesh Bhandari, Jaffey M. Mathew, K. Ashwini, Michael L. J. Pais, Mallappa Kumara Swamy, and Manjeshwar Shrinath Baliga 15 Anticancer Properties of Curcumin and Its Efficacy for Treating Central Nervous System Neoplasms / Neil V. Klinger and Sandeep Mittal 16 Vitamin E: Nature’s Gift to Fight Cancer / Siti Syairah Mohd Mutalip 17 Use of Plant Secondary Metabolites as Nutraceuticals for Treatment and Management of Cancer: Approaches and Challenges / Zahid H. Siddiqui, B. Hareramdas, Zahid K. Abbas, Talat Parween, and Mohammad Nasir Khan 18 Usefulness of Ocimum sanctum Linn. in Cancer Prevention: An Update / Naveen Kaushal, Suresh Rao, Preety Ghanghas, Soniya Abraham, Thomas George, Sueallen D’souza, Jeffey M. Mathew, Jessica Chavali, Mallappa Kumara Swamy, and Manjeshwar Shrinath Baliga 19 Phytochemicals with Anticancer Potential: Methods of Extraction, Basic Structure, and Chemotherapeutic Action / Gulrez Nizami and R. Z. Sayyed 20 Anticancer Plants and Their Conservation Strategies: An Update / Vankayalapati Vijaya Kumar, Mallappa Kumara Swamy, and Mohd. Sayeed Akhtar 21 Anticancer Plants: Chemistry, Pharmacology, and Potential Applications / V. D. Ravichandra, C. Ramesh, Mallappa Kumara Swamy, B. Purushotham, and Gudepalya Renukaiah Rudramurthy 22 Botany, Chemistry, and Pharmaceutical Significance of Sida cordifolia: A Traditional Medicinal Plant / Hassan Ahmed, Abdul Shukor Juraimi, Mallappa Kumara Swamy, Muhammad Saiful Ahmad-Hamdani, Dzolkifli Omar, Mohd Yusop Rafii, Uma Rani Sinniah, and Mohd Sayeed Akhtar 23 Anticancer Properties of Natural Compounds on Prostate Cancer / Priyadarshini and Abhishek Negi 24 Phytochemicals Against Cancer Stem Cells / Kok Hoong Leong, Kin Weng Kong, and Lip Yong Chung
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    Publication Date: 2012-08-23
    Print ISSN: 0233-111X
    Electronic ISSN: 1521-4028
    Topics: Biology
    Published by Wiley
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  • 6
    Publication Date: 2013-04-10
    Electronic ISSN: 2168-0485
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
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