Publication Date:
2021-05-19
Description:
Bioguided fractionation of Agelas cerebrum crude extract resulted in isolation of four bromopyrrole and four bromopyrrole
aminoimidazole alkaloids, identified as 5-bromopyrrole-2-carboxylic acid (1), 4-bromopyrrole-2-carboxylic acid (2),
3,4-bromopyrrole-2-carboxylic acid (3), 4,5-bromopyrrole-2-carboxylic acid (4), oroidin (5), bromoageliferin (6), dibromoageliferin
(7) and dibromosceptrin (8) on the basis of spectroscopic data analyses (UV, IR, HRMS, 1D and 2D NMR) and comparison with
literature data. This is the first report of compounds 2 and 3 in a marine sponge belonging to the Agelas genus and the first evidence of the presence of 1 from a natural source.
Description:
Published
Description:
Agelas cerebrum, bromopyrrole alkaloids, antitumoral, antiprotozoal activity
Keywords:
Chemistry
;
Alkaloids
;
Sponges
;
Alkaloids
;
Sponges
;
Chemistry
Repository Name:
AquaDocs
Type:
Journal Contribution
