Publication Date:
2012-09-18
Description:
Hybrid sterility is a major form of postzygotic reproductive isolation that restricts gene flow between populations. Cultivated rice (Oryza sativa L.) consists of two subspecies, indica and japonica; inter-subspecific hybrids are usually sterile. We show that a killer-protector system at the S5 locus encoded by three tightly linked genes [Open Reading Frame 3 (ORF3) to ORF5] regulates fertility in indica-japonica hybrids. During female sporogenesis, the action of ORF5+ (killer) and ORF4+ (partner) causes endoplasmic reticulum (ER) stress. ORF3+ (protector) prevents ER stress and produces normal gametes, but ORF3- cannot prevent ER stress, resulting in premature programmed cell death and leads to embryo-sac abortion. Preferential transmission of ORF3+ gametes results in segregation distortion in the progeny. These results add to our understanding of differences between indica and japonica rice and may aid in rice genetic improvement.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yang, Jiangyi -- Zhao, Xiaobo -- Cheng, Ke -- Du, Hongyi -- Ouyang, Yidan -- Chen, Jiongjiong -- Qiu, Shuqing -- Huang, Jianyan -- Jiang, Yunhe -- Jiang, Liwen -- Ding, Jihua -- Wang, Jia -- Xu, Caiguo -- Li, Xianghua -- Zhang, Qifa -- New York, N.Y. -- Science. 2012 Sep 14;337(6100):1336-40. doi: 10.1126/science.1223702.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Key Laboratory of Crop Genetic Improvement and National Centre of Plant Gene Research, Huazhong Agricultural University, Wuhan 430070, China.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22984070" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
Chimera/*genetics
;
Endoplasmic Reticulum Stress/genetics
;
Germ Cells, Plant/metabolism
;
Molecular Sequence Data
;
Open Reading Frames/genetics
;
Oryza/cytology/*genetics
;
Plant Infertility/*genetics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
