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  • Nature Publishing Group  (3,639)
  • Cambridge University Press  (1,996)
  • Geological Society of America (GSA)
  • 1980-1984  (5,635)
  • 1975-1979
  • 1983  (5,635)
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  • 1
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] TPA, an activator of protein kinase C, triggers platelet aggregation as well as the secretion of [14C]-serotonin from platelets11-13. The response to activation by 1 mM TPA at 37 C, with constant stirring, is more gradual than the response to activation by O.1Uml-1 thrombin and maximal aggregation ...
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  • 2
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    Nature 306 (1983), S. 503-503 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] GASKELL REPLIES-While recognizing that the main point of Jordan's comment is to attempt to correct the allegedly misleading generalizations made by Fair all1 and myself2, I must state that the size of the forbidden line emitting region in Fairall 427 is not an open question. If one looks at ...
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  • 3
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    Nature 306 (1983), S. 731-731 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE article on page 756 from Dr P. W. J. Rigby's group at Imperial College is an intriguing document which is plainly of the utmost importance, but for reasons which, at this stage, are not fully apparent. The obvious difficulty is that the observations described bear on such a variety of important ...
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  • 4
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    Nature 306 (1983), S. 727-730 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WRITING some thirty years ago, Hermann Bondi suggested that in astronomy, observations had proven a less reliable arbiter of hypotheses than had theoretical considerations1 . Subsequent historical studies have widened and deepened knowledge of some of the instances cited by Bondi and have uncovered ...
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  • 5
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    Nature 306 (1983), S. 733-736 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE cellular myc gene may, depending on your point of view, be seen as either the most illuminating or the most confusing of the cellular oncogenes. The promise of illumination lies in the overwhelming circumstantial evidence that c-myc activation in some lymphoid tumours is a direct subversion, ...
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  • 6
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    Nature 306 (1983), S. 737-738 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] AFTER some years of increasing interest, rapid progress is now being made in the understanding of lignin biodegradation. Research in a number of laboratories has culminated in the isolation by T.K. Kirk and Ming Tien of a purified enzyme able to depolymerize lignin1. This enzyme, isolated from the ...
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  • 7
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    Nature 306 (1983), S. 739-740 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ALTHOUGH an ever-increasing number of pharmacologically active peptides are being found in neurones of the central nervous system, it is still not proving possible to find out precisely what neuro-transmitter or neuromodulator functions they perform. This may not be so surprising when one remembers ...
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  • 8
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    Nature 306 (1983), S. 741-741 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN a letter dated Tokio, October 3, Prof. James Main Dixon writes:- "During the two or three days at the end of August we enjoyed fine dry weather, but the sun was copper-coloured and had no brightness. When we got to Nikko, the people came to us to inquire if some catastrophe were impending, for ...
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  • 9
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    Nature 306 (1983), S. 742-742 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] CAIRNS AND LOGAN REPLY - In the first half of his letter, Dr Holliday gives three reasons for thinking that programmed cell senescence is not a protection against the development of cancer. We believe that each of the arguments is fallacious. The common human cancers, as described in textbooks of ...
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  • 10
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    Nature 306 (1983), S. 743-746 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The date of the Crucifixion has been debated for many years, but there has been no agreement on the year nor the day. Astronomical calculations have now been used to reconstruct the Jewish calendar in the first century AD and to date a lunar eclipse that biblical and other references ...
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  • 11
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    Nature 306 (1983), S. 747-751 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Tropospheric ions are of considerable interest as they have the potential to induce aerosol formation and because in situ measurements of their composition are a powerful tool for neutral trace gas detection. The first measurements of tropospheric ion compositions are now ...
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  • 12
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A cDNA clone corresponding to a mRNA present at elevated levels in transformed fibroblasts encodes a Qa / Tla class I major histocompatibility complex (MHC) antigen. High levels of this mRNA are found in all tumour cells tested; the transcript can undergo alternative splicing; and a repetitive ...
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  • 13
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    Nature 306 (1983), S. 765-766 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Our model of photon oscillations is a simple extension of the standard gauge theory of strong interactions wherein an additional gauged U'(l) factor is adjoined to the usual spontaneously broken SU(3) xSU(2) xU(1). Known particles transform trivially under U'(1). At this point, the model involves ...
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  • 14
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    Nature 306 (1983), S. 768-770 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Graphitic particles can only be produced by combustion processes. If one excludes natural burning processes that are not expected to be a significant source during winter and spring when Arctic haze is at a maximum, then one can attribute these particles directly to anthropogenic combustion ...
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  • 15
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    Nature 306 (1983), S. 772-773 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] More than half a century ago it was postulated that coal was a 'polymeric' or macromolecular substance1-3. However, the evidence has not been completely convincing, and the particular nature of the macromolecular state has remained uncertain. Boddy4 found that coals, which normally exhibit brittle ...
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  • 16
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    Nature 306 (1983), S. 662-666 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The β-globin gene present on the deletion locus in a Dutch γβ-thalassaemic patient was found to be identical to the normal β-globin gene with respect to DNA sequence and its transcription in HeLa cells. DNase I sensitivity and methylation experiments show that the affected ...
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  • 17
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    Nature 306 (1983), S. 670-673 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The lines in the spectrum of the Zurich sunspot index in the interval 100 〈 t 〈 8 yr (where t is the period) match those of a model in which a 22-yr carrier 'wave' representing the Hale 22-yr cycle is amplitude modulated (AM) at the 90 yr (Gleissburg) period in the presence of a small but ...
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  • 18
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    Nature 306 (1983), S. 676-677 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] An observed deficiency of chloride ions in coastal aerosols in some locations has been attributed to a reaction of HNO3 or NO2 with NaCl (refs 7-12). Gaseous HC1 has been assumed to be the product based on studies11,12 showing that 0.1-100 p.p.m. NO2 reacted rapidly with moist NaCl aerosols to ...
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  • 19
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    Nature 306 (1983), S. 679-680 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The anorthosites were emplaced into presumed Archaean quartzof eldspathic gneisses, although in large areas of the Grenville Province, both massifs and basement rocks were reworked during late Proterozoic (about 1,000 Myr) Grenvillian metamorphism5. The Adirondack anorthosite may have crystallized ...
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  • 20
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The basicranium is part of a dorsoventrally crushed skull and upper dentition of Diacodon alticuspis, an erinaceomorph from the Lower Eocene (Wasatchian North American Land Mammal Age, about 52 Myr BP) of northern New Mexico7. The specimen was collected in 1946 by an American Museum of Natural ...
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  • 21
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    Nature 306 (1983), S. 688-691 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Indirect immunofluorescence techniques were used to identify the cholinergic and substance P-containing neurones of the midbrain and pontine tegmentum of young adult male rats (150-200 g, Wistar). To increase the levels of ChAT and substance P in cell bodies, the animals were given an injection of ...
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  • 22
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] There is considerable evidence that the major immunogen is situated on VP1, one of the four capsid proteins1-5. Furthermore, the position of the major immunogenic site on VP1 of virus of serotype 0 has been shown to lie within the amino acid tract 141-1606-8. The same region of VP1 from other ...
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  • 23
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The Thy-1 glycoprotein exists in two allotypic forms, Thy 1.1 and Thy 1.2 (ref. 4). It has been proposed that an arginine residue at position 89 corresponds to the Thy 1.1 allotype and a glutamine residue to Thy 1.2 (ref. 5). Since the two proteins differ by only a single residue, they offered a ...
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  • 24
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    Nature 306 (1983), S. 699-701 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Trypanosoma brucei rhodesiense, causative agent of East African sleeping sickness in man, also infects domestic and game animals. As the sole criterion for distinguishing T. b. rhodesiense from T. b. brucei is the former's infectivity to man, any T. brucei group stock isolated from reservoir host ...
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  • 25
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    Nature 306 (1983), S. 704-707 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Previously we have isolated two recombinant plasmids (pYA102 and pYA208) containing overlapping DNA fragments which harbour the yeast actin gene8,9. In studying the region 5' to the actin gene we detected another gene whose transcription product is a polysomal RNA coding for a protein of 20,000 ...
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  • 26
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    Nature 306 (1983), S. 707-709 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The transforming genes of Harvey and Kirsten murine sarcoma viruses have been named ras oncogenes because these two oncogenic retroviruses were originally isolated by passage of murine leukaemia viruses in rats1. The ras oncogene of Harvey murine sarcoma virus has been named v-rasH and that of ...
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  • 27
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    Nature 306 (1983), S. 709-712 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We have previously shown that linker histone (H1 and H5) induced chromatin condensation, as measured by electron microscopy, is directly proportional to the sedimentation rate5. Here we have used the sedimentation rate of chromatin as the primary measure of its higher order folding. Our ...
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  • 28
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    Nature 306 (1983), S. 713-714 
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    Notes: [Auszug] THIS is the book we have been waiting for. Fifteen years ago, the neutral theory was proposed by Kimura, and independently by King and Jukes. In Kimura's formulation, it made two assertions. First, chance events have been more important than natural selection in bringing about evolutionary changes ...
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  • 29
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    Nature 306 (1983), S. 714-714 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE realization in the early 1970s that free radicals are a normal component of the Earth's lower atmosphere revolutionized our understanding of atmospheric chemistry and its role in the larger biogeo-chemical cycling of the elements. However, the advances made in this field over the past decade ...
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  • 30
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    Nature 306 (1983), S. 714-715 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] As most historians portray it, science is a linear sequence of triumphant discoveries. Occasionally we hear of scientists who were mistaken, just so long as they were mistaken in big ways. But most scientists fail in the most literal sense of this term. They may publish a few papers, but these ...
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    Nature 306 (1983), S. 715-715 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] GLIMPSE of 1986 - an artist's impression of the International Solar Polar Mission spacecraft (which is now completed) atop a Centaur upper stage after its deployment from the Space Shuttle. The illustration is taken from a new publication of the European Space Agency, The International Solar Polar ...
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  • 32
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    Nature 306 (1983), S. 521-521 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] How, in the long run, can a modern state hope to deal equitably with its pensioners, especially if a substantial fraction of its putatively working population is forced into premature pensionhood by unemployment? And what if the social burden of the unemployment rolls will in any case be made ...
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    Nature 306 (1983), S. 522-522 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] ROBERT Nozick, the Harvard University philosopher, wrote last week in the New York Times that animal rights is a subject that seems to attract cranks. The distinguishing feature of a crank, he was quick to point out, is not merely preoccupation with a single issue; the solving of the world's ...
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    Nature 306 (1983), S. 522-522 
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    Notes: [Auszug] How would you find out whether a ball that bounces best on one surface bounces best on all surfaces? How would you tell why a snail will not cross a ring of salty water? These are some of the questions that have been put to 11-year-olds in British primary schools by a group of investigators from ...
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    Nature 306 (1983), S. 523-523 
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    Notes: [Auszug] THE Agricultural and Food Research Council (AFRC) has now completed its strategic plan, intended as an adaptation to the expected substantial drop in its share of the science budget over the next few years. The plan, which has not yet been ratified, will be discussed next week at a meeting of ...
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    Nature 306 (1983), S. 523-523 
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    Notes: [Auszug] NATURE is able today to report the exciting news that there is life - of a kind - in outer space. Through the marvels of modern communications, President Ronald Reagan, Chancellor Helmut Kohl of West Germany, your correspondent and a few other European journalists were able on Monday to direct ...
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    Nature 306 (1983), S. 524-524 
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    Notes: [Auszug] THE Linus Pauling Institute of Science and Medicine in Palo Alto, California, has settled yet another lawsuit brought by a former employee who claimed to have been dismissed from a tenured research position. Dr Fred West all, who worked at the institute in 1978 and 1979, had accused Pauling of ...
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    Nature 306 (1983), S. 524-524 
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    Notes: [Auszug] Chicago UNDAUNTED by 12 years of intermittent controversy, distinguished academics continue to flock to the annual conference on "the unity of the sciences" sponsored by Reverend Sun Myung Moon's Unification Church. This year's conference, held here last week, heard the Nobel economist F.A. Hayek ...
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    Nature 306 (1983), S. 525-525 
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    Notes: [Auszug] THE Wildlife and Countryside Act, introduced two years ago, has run into serious trouble. British conservation groups are complaining that the act fails to provide adequate protection to places designated by the Nature Conservancy Council (NCC) as Sites of Special Scientific Interest (SSSIs). The ...
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    Nature 306 (1983), S. 525-525 
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    Notes: [Auszug] FINLAND is planning a massive modification of its environmental legislation over the next ten years. At present, the laws of environmental protection are a confused collection of ad hoc acts introduced piecemeal to cope with specific problems. The need for a legislative review was underlined by the ...
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    Nature 306 (1983), S. 526-526 
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    Notes: [Auszug] OUT of the political and economic gloom over the Athens summit earlier this week, where European Prime Ministers were attempting to thrash out a solution to the European Community's burgeoning "budget problem", officials were hoping for a little "green light" for biotechnology. The heads of ...
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    Nature 306 (1983), S. 526-526 
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    Notes: [Auszug] EVEN if French academic computing power is behind that of the United Kingdom and West Germany (see Nature304,298; 1983), things may be looking up. After two years of often bitter negotiations, the biggest scientific campus in France - the Universit de Paris Sud at Orsay - has at last been granted a ...
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    Nature 306 (1983), S. 527-527 
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    Notes: [Auszug] Canberra THE Labour Government has been busily reversing the free-market bent of Mr Malcolm Eraser's policy on telecommunications in order to keep it in the public sector. The latest policy reversal is the decision on 15 November to retain full ownership of Aussat Pty Ltd, the company set up to ...
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    Nature 306 (1983), S. 527-527 
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    Notes: [Auszug] IN a stout defence of laboratory animal experiments, Sir Andrew Huxley, president of the Royal Society, last week let slip that he personally countersigns 1,500 applications a year by researchers to the Home Office - and that he sends about 100 of them back for amendment before adding his ...
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    Nature 306 (1983), S. 528-528 
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    Notes: [Auszug] Stockholm THE Sixth International Conference on Collective Phenomena last week cast light on the problem of scientific "refusniks" in the Soviet Union. Although many Western scientists have in the past ten years visited the regular Sunday seminars organized by the refusniks (Jewish scientists ...
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    Nature 306 (1983), S. 528-528 
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    Notes: [Auszug] EUROPEAN publishers were last week astounded by the announcement by Academic Press London (APL) that it is to make redundant more than half of its 247-strong workforce. The recent history of APL has been troubled (see Nature 303, 192; 1983) and changes were expected, but the scale of job losses ...
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    Notes: [Auszug] GENETICS Institute, the Cambridge (Massachusetts) biotechnology corporation, claimed last week important progress towards the production of factor VIII, the blood-clotting agent in which haemophiliacs are deficient. The institute says that it should have been able to clone and express the gene for ...
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    Nature 306 (1983), S. 528-529 
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    Notes: [Auszug] RELIGIOUS fundamentalists are shifting their efforts to local school boards, having largely failed in the courts and state legislatures to force the teaching of "creation science" in public schools. The current multiplicity of relatively low-key efforts seems, at least in some areas, to be paying ...
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    Nature 306 (1983), S. 529-529 
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    Notes: [Auszug] ENCOURAGING signs of life in British biotechnology have been discovered by Biotechnology Investments Limited (BIL), the two-and-a-half-year-old company sponsored by the merchant bank N. M. Rothschild & Sons Limited. Since the end of May, when BIL's second annual report showed investments of ...
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    Nature 306 (1983), S. 530-530 
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    Notes: [Auszug] SIR - In the argument about numerology (Nature 7 July, p. 11 and 1 September, p.8), both the numerologists and their critics miss the point. Being impressed by the near match of numbers does not make science, nor is it scientific simply to stress the remaining inaccuracy and complain of the lack of ...
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    Nature 306 (1983), S. 531-531 
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    Notes: [Auszug] LEXICOGRAPHERS have been dismayed, but word-game players no doubt delighted, by the appearence on the scene of the word yrast, one of the rare contributions of the Swedish language to international usage. (The word is apparently the superlative of the adjective gr, which means "dizzy".) Its ...
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    Nature 306 (1983), S. 532-533 
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    Notes: [Auszug] ON 17 August 1983, the GlomarChallenger docked in St. John's, Newfoundland, with more than two miles of sediment cored from a climatically critical region of the North Atlantic Ocean. This ended a voyage begun 55 days earlier in Norfolk, Virginia, that took the Challenger to a transect of six sites ...
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    Nature 306 (1983), S. 533-534 
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    Notes: [Auszug] IN its early days, the science of ethology was devoted largely to the description of the behaviour patterns of animals. Today, however, the subject encompasses a wide range of disciplines, as indicated by the themes of the Plenary Sessions at the 18th International Ethological Conference*: ...
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    Nature 306 (1983), S. 535-537 
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    Notes: [Auszug] SINCE introns and exons were discovered six years ago, the split organization of eukaryotic genes has been seen as a mechanism for enhancing the rateof evolutionary change. First, Gilbert1 put forward the important hypothesis that exons correspond to protein functions which can be reshuffled by ...
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    Nature 306 (1983), S. 537-538 
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    Notes: [Auszug] THE I region of the mouse major histo-compatibility complex (H-2) codesfor cell surface glycoproteins referred to as class II molecules but previously known as I-region associated or Ia antigens. The class II molecules areheterodimers of two trans-membrane glycoproteins, a 32,000 molecular ...
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    Nature 306 (1983), S. 538-539 
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    Notes: [Auszug] AT a recent workshop* in Edinburgh investigators from forty different laboratories grappled with the idiosyncratic properties of more than 100 monoclonal antibodies raised against HLA Class II antigens. These glycoproteins, also known as la antigens, are of great interest because of their ...
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    Nature 306 (1983), S. 539-540 
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    Notes: [Auszug] Two new papers appearing in Nature1,2 add those with an interest in mitochondria to the ever-growing list of scientists required to understand something of the major histocompatibility complex (MHC). Not so many years ago the MHC was commonly thought to be too complex to be comprehensible to all ...
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    Nature 306 (1983), S. 540-540 
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    Notes: [Auszug] ECDYSTEROIDS, the hormones controlling development in arthropods and present in certain plant families, have now been found in helminth parasites of humans and livestock (trematodes1, filarial nematodes2 and cestodes3,4). As reported at a recent conference*, one result - of great potential ...
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    Nature 306 (1983), S. 541-545 
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    Notes: [Auszug] Deuterium and water contents of rhyolite obsidian tephra clasts and lava flows sampled in the western USA decrease within each eruptive sequence, from D- and H2O-rich, explosive (Plinian) eruptions, to D- and H2O-depleted lava flows. These changes result not from volatile ...
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    Nature 306 (1983), S. 545-550 
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    Notes: [Auszug] Sulphur isotope analyses reveal that the fossil hydrothermal pyrite mound and tubes at Silvermines were produced by the reaction of hydrothermal Fe(II) with bacteriogenically-reduced sulphur species (δ34S range:−18.4 to −42.5%). This took place in a brine pool ...
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    Notes: [Auszug] Nucleotide sequence and deletion analysis have been used to identify the regulatory and coding sequences comprising the cholera toxin operon (ctx). Incorporation of defined in vitro-generated ctx deletion mutations into Vibrio cholerae by in vivo genetic recombination produced strains which have ...
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    Notes: [Auszug] DNA sequences containing the 5′-flanking regions of the insulin and chymotrypsin genes were linked to the coding sequence of the chloramphenicol acetyltransferase (CAT) gene. The insulin gene recombinant elicits preferential expression of CAT activity when introduced into cells producing ...
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    Notes: [Auszug] The β-adrenergic receptor binding subunits from frog erythrocytes, hamster lung and guinea pig lung have been purified to apparent homogeneity and in all cases reside on a single polypeptide. Insertion of the pure receptors into phospholipid vesicles and subsequent fusion of these vesicles ...
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    Nature 306 (1983), S. 566-568 
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    Notes: [Auszug] We have three sets of observations on which the actual discovery7 of a radio supernova in NGC4258 is based: (1) a combination of data taken with the Westerbork Synthesis Radio Telescope (WSRT) in 1974-75 and data taken with the Very Large Array (VLA) in June 1979 at 1,415 and 1,480 MHz ...
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    Nature 306 (1983), S. 568-569 
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    Notes: [Auszug] The short-period end of the pulsar distribution is dominated by the Crab and Vela pulsars: they are typical young objects with a vigorous energy output, and, because of their unique evolutionary status, have served as a basis for much of the theoretical debate on pulsars' emission mechanisms (see, ...
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    Nature 306 (1983), S. 607-609 
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    Notes: [Auszug] DNA attached to a protein matrix was isolated from hen oviducts and digested with the restriction enzyme EcoRI. The released (85% of total) and bound (15% of total) fractions were separated quantitatively and analysed by gel electrophoresis, blotted to nitrocellulose by the method of Southern13 and ...
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    Notes: [Auszug] For the isolation of IGF-I cDNA we used a cDNA library derived from human adult liver12. This library was constructed by preparing double-stranded cDNA from poly (A)-containing mRNA and inserting it into the Pstl restriction site of the pBR322 derivative pKT21813, using the dG-dC tailing technique. ...
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    Nature 306 (1983), S. 615-616 
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    Notes: [Auszug] Genomic DNA was prepared from peripheral blood of individuals typed for C4 and samples were digested with various restriction endonucleases, the resulting fragments separated by agarose gel electrophoresis, transferred to nitrocellulose filters and hybridized with a 32P-labelled cDNA probe known to ...
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    Notes: [Auszug] A human genomic DNA library22 was screened for phage carrying preproenkephalin B (alternatively designated prepro-dynorphin) gene sequences by hybridization in situ23 at 60 C with a porcine cDNA probe1. To examine whether the initial phage clones thus obtained carried the entire mRNA-coding ...
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    Nature 306 (1983), S. 616-617 
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    Notes: [Auszug] Among a collection of Enterobacteriaceae made by E. D. G. Murray between 1917 and 1954, 84 (19%) transferred conjugative plasmids to E. coli K-12. Of these, 36 determined colicinogeny, one determined tellurite resistance and 47 were cryptic1. We labelled cryptic conjugative plasmids with antibiotic ...
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    Notes: [Auszug] We first related the ability of EGF to stimulate DNA synthesis with expression of EGF receptors by WI-38 cells of various in vitro ages. The in vitro age of WI-38 cultures was monitored using two indices, population doubling level (PDL)22 and per cent of the replicative lifespan completed (PLC)23; ...
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    Nature 306 (1983), S. 620-622 
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    Notes: [Auszug] Procedures used for preparation of high-speed cytoplasmic extracts (HSE) from Xenopus eggs are outlined in Fig. 1. When HSE is incubated at 18-25 C, a distinct gel forms which slowly contracts over a period of 12-24 h. Actin is a main component of the gel as shown by the following criteria: (1) a ...
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    Nature 306 (1983), S. 623-623 
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    Notes: [Auszug] WHEN distinguished physicists reach the age of sixty - or some similar milestone - it is not unusual to celebrate the occasion by bringing out a festschrift made up of papers written on request by friends and colleagues. These volumes must be a source of satisfaction to the person so honoured but ...
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    Nature 306 (1983), S. 623-624 
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    Notes: [Auszug] IN his Presidential Address to the Geochemical Society in 1976, Karl Turekian said "... one has the feeling that the whole field of trace metal marine geochemistry would have been a completely dull one over the past fifty years if it weren't for analytical errors! The startling conclusion, as the ...
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    Nature 306 (1983), S. 624-625 
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    Notes: [Auszug] EVOLUTIONARY theory is as attractive to biologists now as it has ever been. Most social scientists, however, continue to resist its allure, recalling the malign influence of nineteenth century evolutionism in the social arena. It is no surprise, then, that these two books on the relationship ...
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    Nature 306 (1983), S. 625-625 
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    Notes: [Auszug] BLUE skies and red sunsets intrigued Leonardo de Vinci and stimulated some of the best scientific compositions of Tyndall and Lord Rayleigh. While no longer an enigma to a generation which was exposed to essays on sky colour in the classics of children's scientific literature and which witnessed ...
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    Nature 306 (1983), S. 626-626 
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    Notes: [Auszug] FASCINATING insights into the evolution of nature's elements and the subsequent history of our Solar System can be obtained from the study of elemental abundances and isotopic anomalies in terrestrial, meteoritic and lunar materials. In this book, Paul Kuroda examines some of the facets of this ...
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    Nature 306 (1983), S. 625-626 
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    Notes: [Auszug] IN 1980, T.C. Whitmore wrote: "The second half of the twentieth century will stand in history as the brief period during which Man reduced the area of the richest and most complex ecosystems in the world by one third". The ecosystems he referred to, of course, are the world's tropical rain forests ...
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    Nature 306 (1983), S. 626-626 
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    Notes: [Auszug] AT first sight this book appears to be all that English-speaking orchid enthusiasts have been waiting for - an authoritative up-to-date account of European orchids. Indeed, it is claimed to be so by the authors. The photographs are excellent but, unfortunately, the text does them scant justice as ...
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    Nature 306 (1983), S. 411-412 
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    Notes: [Auszug] THE Soviet Union's walk-out last week from the arms control negotiations at Geneva may not be quite the calamity that it seems: that is the bright side of the coin. For this development, well flagged in advance as the probable response to the first appearance in Europe of the cruise and Pershing II ...
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    Nature 306 (1983), S. 412-412 
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    Notes: [Auszug] Is the British Government's wind power programme in the doldrums? Earlier this year, the Department of Energy's advisory committee on research and development put wind at the top of the list of renewable sources of energy, saying at the same time that wave power is unlikely to be economic. As a ...
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    Nature 306 (1983), S. 413-413 
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    Notes: [Auszug] THE launch earlier this week from Cape Canaveral in Florida of the shuttle craft carrying the Spacelab experiment probably marks a turning point in collaboration on space projects between the European Space Agency (ESA) and the National Aeronautics and Space Administration (NASA) in the United ...
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    Nature 306 (1983), S. 413-413 
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    Notes: [Auszug] THE Max-Planck-Gesellschaft (MPG), West Germany's largest academic research organization outside the universities, will have a new president when Heinz Staab takes over from Reimar Lust in July 1984. The MPG has an annual budget of DM950 million (£240 million), of which 6 per cent comes from ...
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    Nature 306 (1983), S. 471-473 
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    Notes: [Auszug] As a lineage-linked cell marker, we used dextran (MW 10,200) covalently attached to fluorescein (1:1 molar ratio), for visualization by fluorescence microscopy, and to lysine (approximate 3:1 molar ratio), to ensure co-fixation with protein in buffered formaldehyde fixative (R. Gimlich and J. ...
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    Nature 306 (1983), S. 505-505 
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    Notes: [Auszug] DNA for Beginners. By Israel Rosenfield, Edward Ziff and Borin Van Loon. Writers & Readers (distributed by W. W. Norton): 1983. Pp.223. Pbk $6.95. To be published in the UK in February 1984, price £2.95. Hi Brid Vygor stood on the bridge of his ship, the James Dewey Watson, ...
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    Nature 306 (1983), S. 507-507 
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    Notes: [Auszug] The Atlas of the Solar System. By Patrick Moore, Garry Hunt, Iain Nicolson and Peter Cattermole. published by Mitchell Beazley/Rand McNally: 1983. Pp.464. £19.95, $40. PUBLICATION of an atlas of the Solar System in 1983 is a shrewd choice. The rich veins of planetary imagery mined by ...
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    Nature 306 (1983), S. 509-509 
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    Notes: [Auszug] We received a third book on elementary particles for the layman after Nigel Calder's review (above) was complete: The Quest for Quarks by Brian McCusker (Cambridge University Press; £7.95, $14.95). Unfortunately, it would appear to fall into the same errors Calder criticizes - but it ...
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    Nature 306 (1983), S. 510-511 
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    Notes: [Auszug] Are Computers Alive? Evolution and New Life Forms. By GeoffSimons. Harvester/Birkhauser: 1983. Pp.212. £9.95, $18.95. A PAPERBACK that caused some excitement in my schooldays was entitled Meet Yourself as You Really Are. Similar in plan to a "programmed learning" text, it took you ...
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    Nature 306 (1983), S. 513-514 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] COUNTLESS birders in North America and Europe took their first steps in bird identification with a "Peterson guide". When A Field Guide to the Birds of Britain and Europe (Collins, £7.95) was first published in 1954, Roger Tory Peterson's illustrations were a relevation: overnight, bird ...
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    Nature 306 (1983), S. 515-515 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fossils: the Key to the Past. By Richard Fortey British Museum (Natural History): 1983. Pp.172. Pbk £6.50 (£5.95 at the Museum). Collins Guide to Dinosaurs. Published By David Lambert Collins/Avon: 1983. Pp.256. £6.95, $8.95. MANY fine popular books about palaeontology ...
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    Nature 306 (1983), S. 309-309 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Washington THE Soviet Union's "Food Programme" appears to be making small but real progress towards reducing the country's dependence on imported grains and increasing domestic production of meat, according to the US Department of Agriculture (USDA). USDA estimates that the Soviet grain crop this ...
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    Nature 306 (1983), S. 310-310 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR - We share the concern of scientists in India about the plans of the Indian Government to build a "technology city" for Indian scientists trained abroad at a reported cost of $125 million (Nature 29 September, p.350). We suggest that the money be used, instead, for building a new ...
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    Nature 306 (1983), S. 719-719 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ONE of the established conventions in British politics is that if a government is required to make public some decision which it would prefer not to see widely discussed, it does so by means of what is called a "written" answer to a parliamentary question at the very end of a parliamentary session. ...
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    Nature 306 (1983), S. 720-720 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] NOBODY will be surprised that the new government in Buenos Aires is less keen than its military predecessors on making nuclear weapons, but the report of what has been said in Argentina (see p. 724) since last month's elections is encouraging. Since the late 1950s, Argentine governments have been ...
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    Nature 306 (1983), S. 721-721 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE Director of Public Prosecutions is this week considering whether there is a case for criminal proceedings against British Nuclear Fuels Limited (BNFL) over last month's accidental radioactive discharge into the sea from its fuel reprocessing plant at Sellafield (formerly Windscale) in Cumbria. ...
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    Nature 306 (1983), S. 722-722 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SANDIA National Laboratories, founded in 1945 to provide engineering support for the Manhattan Project at Los Alamos, continues to be chiefly concerned with weapons research, development and testing. Its increasing strength in basic science, however, particularly in the pulsed power research ...
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    Nature 306 (1983), S. 723-723 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR Keith Joseph, Secretary of State for Education and Science in the British Government, las week gave notice of how the £549 million his department intends to spend directly on scientific research next year will be allocated between the five research councils. The total available for the ...
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    Nature 306 (1983), S. 724-724 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] PRESIDENT-elect Raul Alfonsin of Argentina, as one of his first acts, has ordered the drafting of a new law to control the country's nuclear energy programme. Foreign minister-designate Dante Caputo, speaking on Buenos Aires radio, said that the purpose of the law will be to study the organization ...
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    Nature 306 (1983), S. 724-724 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] BRITAIN and West Germany last week dealt a blow to Esprit, Europe's fledgling and belated effort to coordinate research and development in information technology. Esprit has been heralded by European industry as the best research plan ever to emerge from the Brussels-based European Commission, and ...
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    Nature 306 (1983), S. 725-725 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE Agricultural Genetics Company (AGC), founded in July to exploit biotechnological discoveries in five institutes and one unit of AFRC, hopes to raise about £10 million from new and old investors and to build a laboratory in Cambridge during 1984. Acknowledging that UK government cutbacks ...
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