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  • Nature Publishing Group  (12,082)
  • American Association of Petroleum Geologists (AAPG)
  • American Meteorological Society
  • 1995-1999  (19,236)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature structural biology 2 (1995), S. 28-35 
    ISSN: 1072-8368
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Using the two-hybrid protein interaction reporter system, actin, profilin, Srv2p and two SH3-containing proteins are found to bind yeast actin in vivo. When tested for ability to interact with 35 actin mutations distributed over the monomer surface, distinct subsets of mutations characteristic for ...
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  • 2
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    [s.l.] : Nature Publishing Group
    Nature structural biology 2 (1995), S. 69-76 
    ISSN: 1072-8368
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The crystal structure of the phosphoglycerate dehydrogenase from Eschehchia coli is unique among dehydrogenases. It consists of three clearly separate domains connected by flexible hinges. The tetramer has approximate 222 symmetry with the principal contacts between the subunits forming between ...
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  • 3
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    [s.l.] : Nature Publishing Group
    Nature structural biology 2 (1995), S. 77-80 
    ISSN: 1072-8368
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The average contact distance between protein and solvent surface atoms in cubic insulin crystals has been determined from two sets of 15 Å resolution neutron diffraction data. A contact distance between the water hydrogen sites and the protein surface that is significantly shorter than the ...
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  • 4
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    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A23-, (9 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Studies of the molecular basis of Alzheimer's disease exemplify the increasingly blurred distinction between basic and applied biomedical research.The four genes so far implicated in familial Alzheimer's disease have each been shown to elevate brain levels of the self-aggregating amyloid-β ...
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  • 5
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    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A15-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Epilepsy, a brain disorder that is characterized by recurrent seizures, refers to a collection of disorders that affect 1–2% of the population worldwide. A seizure is a brief change in behaviour caused by the disordered, synchronous and rhythmic firing of populations of neurons in the ...
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  • 6
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    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A32-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Parkinson's disease (PD) is one of the major neurodegenerative disorders of middle and old age, and was originally described by James Parkinson in 1817. It is characterized by a trio of cardinal symptoms—muscle rigidity, tremor and bradykinesia—but can also involve postural deficits and ...
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  • 7
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    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A7-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] There is growing optimism among researchers in the field of brain ischaemia, as human stroke has at last become treatable and current research efforts delineate several new, potential therapies. Most strokes are caused by acute interruption of the brain arterial blood supply by a thrombus, leading ...
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  • 8
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    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A40-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The cause of multiple sclerosis remains unknown after more than a century of study. Unconfirmed work has once more indicated that a viral infection may be important in the aetiology of the disease, and there is considerable evidence for an important genetic influence on disease susceptibility. The ...
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  • 9
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Dimerization is a biological regulatory mechanism employed by both soluble and membrane proteins. However, there are few structural data on the factors that govern dimerization of membrane proteins. Outer membrane phospholipase A (OMPLA) is an integral membrane enzyme which participates in ...
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  • 10
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 468-469 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Most mathematicians find it very difficult to explain to other people what mathematics is and why we find it so absorbing. Even our students generally take some time to see the picture. They spend three or four years studying different parts of it in detail. While this is going on, we point out ...
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  • 11
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] To determine whether c-Abl interacts with ATM, lysates prepared from control and AT lymphoblastoid cells, with or without prior exposure to 5 Gy of ionizing radiation, were subjected to immuno-precipitaiton with c-Abl antibody. Immunoblot analysis of the anti-c-Abl immunoprecipitate with an ...
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  • 12
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 469-470 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Writing in a special issue of the London Times in August 1931 to celebrate the centenary of Michael Faraday's momentous discovery of electromagnetic induction, Lord Rutherford spoke for all scientists when he said: "The more we study the work of Faraday, with the perspective of time, the more we ...
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  • 13
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 323-323 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [WASHINGTON] In the most prominent speech of his presidency on research-related issues, President Bill Clinton called last Sunday (18 May) for Americans to remember that "science is not God" adding: "Our deepest truths remain outside the realm of science." In a speech that has been noticed ...
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  • 14
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    Nature 387 (1997), S. 324-324 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [PARIS] Members of the International Bioethics Committee of the United Nations Educational, Scientific ahdCulturar Organization (Unesco) appear to be divided on the issue of human cloning, on which they are due to produce an interim statement this week, In particular, many are unhappy about ...
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  • 15
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 326-326 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [LONDON] Fifteen African countries unexpectedly seized the initiative last week at a meeting of the United Nations Biodiversity Convention by tabling detailed proposals calling on all signatories to the convention to accept tough regulations governing the use of genetically modified organisms. ...
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  • 16
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 443-443 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [PARIS] France is embarking on a major reorganization of its research in telecommunications, currently carried out mainly by the Centre National d'Etudes des Telecommunications (CNET), part of the state-owned company France Telecom. The reforms include the creation of a national federation - the ...
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  • 17
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 321-321 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The human cloning debate has revealed the growing political importance of bioethics committees in the regulation of new technologies. Confronted with public concern about human cloning, the instant reflex of political leaders worldwide has been to call on the nearest bioethics committee for ...
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  • 18
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 331-333 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Universities across the United States are slowly awakening to a rumbling debate about the nature of scientific practice and knowledge, about who is qualified to pronounce on either-and about the motivation of those who do so. You can call the argument the Science Wars, as some ...
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  • 19
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 334-334 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Despite a few light skirmishes (see opposite), and the fact that the work of various European researchers has been dragged into the conflict in the United States, the Science Wars have so far failed to ignite into a major conflagration in Europe itself. Earlier this year there were signs that ...
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  • 20
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    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 335-335 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] While US campuses, academic journals and newspapers remain the main theatres of action in the 'Science Wars', Britain has had its own 'science skirmish', with scientists and sociologists at loggerheads over the question of public involvement in science policy. The two conflicts, ...
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  • 21
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    Nature 387 (1997), S. 339-339 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir- Six pages of Briefing on fisheries science (Nature 386,105-110; 1997) ably demonstrates why the fisheries sector is in crisis. The reality is that if fishermen meet the market demand for fish, fish stocks will be completely fished out within a very short time. There is only one ...
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  • 22
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    Nature 387 (1997), S. 464-464 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Vervet monkeys (Cercopithecus aethiops) forage on patchily distributed resources, visiting several sites in a single trip. When choosing a route, they face a famous optimization problem, the 'travelling salesman' problem1. Here we pose a question about their route-choosing mechanism: how many ...
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  • 23
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    Nature 387 (1997), S. 466-466 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Turtles have generally been regarded as basal reptiles because they apparently retain the primitive anapsid skull pattern (no temporal fenestrae) unlike other extant reptiles which are diapsid (two temporal fenestrae on each side). However, the phylogenetic relationships between turtles and other ...
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  • 24
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    Nature 387 (1997), S. 362-363 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Late in life, the mathematician Kurt Godel confided that he felt the Institute for Advanced Study at Princeton University had been paying him too much. On the face of it, he had a case: after his appointment as professor, he never lectured or held a seminar, and he published almost nothing. But the ...
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  • 25
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The coupling of ATP hydrolysis to electron transfer by the enzyme nitrogenase during biological nitrogen fixation is an important example of a nucleotide-dependent transduction mechanism. The crystal structure has been determined for the complex between the Fe-protein and MoFe-protein components of ...
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  • 26
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    Nature 387 (1997), S. 379-381 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the experiments described here our aim was to prepare polyhedral Al(i) compounds containing more than four Al atoms using N(SiMe3)2 ligands for protection. A solution of aluminium(i) iodide5 in a solvent mixture of toluene and diethyl ether was added to a solution of base-free LiN(SiMe3)2 at -78 ...
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  • 27
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    Nature 387 (1997), S. 377-379 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The martian meteorite ALH84001 is unique in containing 1 vol.% Mg-Fe-Ca-Mn carbonates, which are dispersed in an orthopyroxenite rock with a few vol.% of plagioclase glass, chromite and silica1'2. Intensive scrutiny of the carbonates has produced many models for their origin but none satisfies all ...
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    Nature 387 (1997), S. 247-247 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Genetic recombination is known to be a source of mitochondrial DNA (mtDNA) variability in plants, fungi and protists1, but there continues to be a consensus (based on studies of somatic cell hybridization2 and DNA repair3) that such processes do not operate on animal mtDNA4. Contrary to this ...
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  • 29
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    Nature 386 (1997), S. 550-551 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Our visual perception of the direction of objects seems to be based on several inaccurate visuomotor processes, which are the subject of two studies by Ross et all and Cai etal2 on pages 598 and 601 of this issue. Even a simple sideways glance to grasp a coffee mug involves visuomotor complexities ...
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    Nature 387 (1997), S. 138-139 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Groups of organisms that have been described as a single taxonomic unit on the basis of quantitative characters are increasingly proving to require more complex classification, when their evolutionary history is studied with molecular markers1. Here we report an analysis of mitochondrial DNA ...
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    Nature 387 (1997), S. 140-140 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] J. Gilley et al. in Scientific Correspondence1 describe the organization of the pufferfish Surfeit locus in a letter entitled "Fugu genome is not a good mammalian model". The wide-ranging conclusions implied by this headline are not supported by the evidence and arguments presented. First, Gilley ...
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    Nature 387 (1997), S. 140-140 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Gilley and colleagues1 present data on the Surfeit genes isolated from the Fugu genome. The Surfeit locus is of particular interest as the genes contained within are tightly packed in both mammals and the chicken and yet dispersed in invertebrates. Unfortunately, the data from Fugu do not support ...
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    Nature 386 (1997), S. 564-564 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Differences in the molecular heterogeneity of the abnormal isoforms of the prion protein, PrPSc, due to differential glycosylation and partial endogenous or exogenous proteo-lysis1'2 have been found in different scrapie strains3, sources of Creutzfeldt-Jakob disease (CJD) and fatal familial ...
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    Nature 387 (1997), S. 141-141 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] This is a ramble of a book. If there is a central theme, it is the role of visual representations in scientific discovery and theory. But in effect the 480 pages are devoted to a long nature walk through the history of physics. The walk takes us to and fro between the centuries and often - too ...
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    Nature 386 (1997), S. 564-564 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Collinge et al. reply - We recently reported that new variant CJD (vCJD) could be distinguished from previously recognized forms of sporadic and acquired CJD by a consistent pattern on western blots with respect to ratios of PrPSc glycoforms after proteinase K digestion6. This pattern resembled ...
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    Nature 386 (1997), S. 567-567 
    ISSN: 1476-4687
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Behavioural Ecology: An Evolutionary Approach. Fourth edition by J.R. Krebs and N.B. Davies Blackwett Science, £26.50, $49.95 Like the previous three editions of this classic behavioural ecology text, this fourth edition brings together a completely new set of chapters to provide an ...
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    Nature 386 (1997), S. 568-568 
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    Notes: [Auszug] Philippe Janvier has excelled himself with this landmark publication, which surely ranks as a modem classic. No other textbook has dealt so clearly with the origins and early evolution of vertebrates. Each chapter is lucidly written and important anatomical features are clearly illustrated, ...
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    Nature 386 (1997), S. 569-577 
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    Notes: [Auszug] The recruitment model for gene activation stipulates that an activator works by bringing the transcriptional machinery to the DNA. Recent experiments in bacteria and yeast indicate that many genes can be activated by this mechanism. These findings have implications for our understanding of the ...
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    Nature 386 (1997), S. 578-584 
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    Notes: [Auszug] Seismic tomography based on P-wave travel times and improved earthquake locations provides further evidence for mantle-wide convective flow. The use of body waves makes it possible to resolve long, narrow structures in the lower mantle some of which can be followed to sites of present-day plate ...
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    Nature 386 (1997), S. 431-431 
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    Notes: [Auszug] Sir-Your recent News article3 on the reaction to sheep cloning suggests that "scientists agree that cloning of humans would be unethical". Indeed, a certain Jeremy Rifkin goes so far as to suggest that penalties for human cloning should be on a par with those for "rape, child abuse and murder". ...
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    Nature 386 (1997), S. 431-431 
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    Notes: [Auszug] Sir-The publication of the experimental protocol through which Dolly came to life1 created a considerable stir in the media. In this context, the arguments put forward in your leading article4 in favour of a mere moratorium rather than total and definitive banning of this type of experiment in ...
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    Nature 386 (1997), S. 432-432 
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    Notes: [Auszug] Sir-I completely agree with Franklin D. Rumjanek about acceptance of papers from developing countries by leading Western scientific journals(Nature 384,509; 1996). I have had several bad experiences and I feel that many of my papers have been arbitrarily rejected. There is one more misdeed ...
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    Nature 386 (1997), S. 432-433 
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    Notes: [Auszug] Sir - I was seized with a sense ofdeja vu while reading of the summary dismissal of Dr Mark Hughes from his position as head of preimplantation and prenatal diagnosis at the US National Institutes of Health (NIH) and the disavowal by the NIH and Georgetown University of any knowledge of his actions ...
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    Nature 386 (1997), S. 441-441 
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    Notes: [Auszug] Witten and Li2 give a very simple scaling argument for the shape of the edge connecting two corners of an elastic icosahedron, depicted in the figure here. Any deformation that involves most of the bonds on the surface costs an energy proportional to the area; therefore, stretching has to be ...
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    Nature 387 (1997), S. 162-164 
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    Notes: [Auszug] Zeolites are aluminosilicates whose three-dimensional structure is made up of corner-sharing SiO4 and A1O4 tetrahedra, with exchangeable cations (M"+) occupying extra framework positions to neutralize charge1'2. One of the most commonly employed materials, Y-zeolite, has a three-dimensional ...
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    Nature 386 (1997), S. 616-619 
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    Notes: [Auszug] Gelatinase A (also known as matrix metalloproteinase-2, MMP-2 or type IV collagenase; EC 3.4.24.24) has a relative molecular mass of 72,000 (72K) and belongs to the group of matrix metalloprotein-ases that are involved in remodelling the extracellular matrix. Gelatinase A is secreted as a proenzyme ...
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    Nature 386 (1997), S. 627-630 
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    Notes: [Auszug] We replaced the carboxy-terminal domain (CTD) of the a-subunit of RNA polymerase (RNAP) (Fig. 1), which is the natural target for many transcriptional activators1"3, with a heterologous protein domain that does not ordinarily mediate transcriptional activation. To do this, we took advantage of the ...
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    Nature 386 (1997), S. 421-421 
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    Notes: [Auszug] Europe's particle physicists can face the future with a fair degree of satisfaction. Following recent international endorsements of CERN, they are set to occupy centre stage in the next generation of facilities at the high-energy frontiers of their discipline. European astronomers, in contrast, are ...
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    Nature 386 (1997), S. 423-424 
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    Notes: [Auszug] [LONDON] Britain's radioactive waste disposal plans were in disarray last week as Nirex, the company charged with the job of waste disposal, effectively abandoned attempts to build an underground repository at Sellafield in the northwest of England. At a meeting of Nirex's board last week, ...
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    Notes: [Auszug] The crystal structure of the 20S proteasome from the yeast Saccharomyces cerevisiae shows that its 28 protein subunits are arranged as an (α1...α7, β1...β7)2 complex in four stacked rings and occupy unique locations. The interior of the particle, which harbours the ...
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    Nature 386 (1997), S. 477-480 
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    Notes: [Auszug] The control of three-dimensional (3D) scroll waves is a more complex problem than the control of their two-dimensional analogues, spiral waves. The dynamics of a 3D scroll wave are determined not only by the properties of the excitable medium but also by the shape of the filament (the vortex line ...
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    Nature 386 (1997), S. 480-482 
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    Notes: [Auszug] The annual riverine discharge (-0.4 X 1015 g) of DOM and particulate organic matter to the oceans8 consists primarily of the degraded remains of terrestrial vegetation and is considered to be refractory to biodegradation9'10. Terrigenous DOM has characteristically elevated C/N ratios, depleted ...
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    Nature 386 (1997), S. 431-431 
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    Notes: [Auszug] Sir-In the Human Fertilisation and Embryology Act 1990 and the Animal (Scientific Procedures) Act 1986, the United Kingdom has a regulatory framework which was already in place and which was applied to the work on the cloning of sheep at the Roslin Institute. Nature has reported accurately and ...
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    Nature 386 (1997), S. 432-432 
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    Notes: [Auszug] Sir-Rumjanek presents the difficulties of publishing a manuscript produced by his group in Brazil, although the quality of the work was essentially the same as papers he published while he was a postdoc in England. He suggested that the referees could be influenced by the geographical location of ...
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    Nature 386 (1997), S. 433-433 
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    Notes: [Auszug] Sir-Why are advertisements for PhD students specifically directed at those who are "under 30" or a "young student"? I am surprised that a journal such as Nature should support such discrimination. Indeed, it may conflict with equal opportunities legislation. I am a mature student, one of many ...
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    Notes: [Auszug] The importance of latent reservoirs for HIV-1 is highlighted by studies of potent antiretroviral drugs that block new rounds of infection and produce a dramatic drop in plasma virus in two weeks. The rapid decline shows that virus production results largely from continuous rounds of virus infection ...
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    Nature 386 (1997), S. 448-448 
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    Notes: [Auszug] In the exuberant world of present-day gravity physics, it is hard to picture research four decades ago when you could count the active people on your ringers. Bob Dicke, who died on 4 March, was a leader in this change, most famously in the discovery of thermal radiation from the Big Bang, which ...
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    Nature 386 (1997), S. 449-450 
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    Notes: [Auszug] Ancient hunters in southern Peru used spear points and knives made of volcanic glass (obsidian). We have located the source of the vast majority of this obsidian; a quarry on the slopes of the Cotallalli volcano in the south central Andes. Chemical analysis of obsidian from this source as well as ...
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    Nature 386 (1997), S. 452-452 
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    Notes: [Auszug] The folded surface of the cerebral cortex contains a mosaic of functionally distinct areas, connected by a network of nerve fibres in the sub-cortical white matter. This network determines, in part, the computations that the cortex performs. The folds help to fit the large sheet-like cortex into a ...
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    Nature 386 (1997), S. 453-454 
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    Notes: [Auszug] Steven Neuse has rescued David Lilienthal from an undeserved growing obscurity. When Lilienthal died aged 81 in 1981, The New York Times ran his obituary on its front page and praised him on its editorial page as "a special citizen" who epitomized public service and administrative competence. ...
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    Nature 386 (1997), S. 456-456 
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    Notes: [Auszug] It is often said that biology is becoming increasingly specialized. What this book shows is that, at least in evolutionary biology, the opposite trend is at work. Many of the questions in evolutionary biology were formulated by generations of scholars specializing in the study of particular groups ...
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    Nature 386 (1997), S. 456-456 
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    Notes: [Auszug] Roger Penrose is devoted to persuading us that the three problems in science that seem to him to be the deepest and most intractable are, somehow, to be solved by the same somewhat vague inspiration. These problems are the quantum theory of gravity, measurement and decoherence in the quantum ...
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    Notes: [Auszug] The electronic band structure of carbon nanotubes presents some peculiar features. Owing to the hexagonal symmetry of a graphene sheet, the Fermi contour expected for a two-dimensional lattice reduces to six points11. In a nanotube, the component of momentum along the circumference of the tube will ...
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    Nature 386 (1997), S. 314-315 
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    Notes: [Auszug] Over 30 years ago, when the then leader of the Labour party, Harold Wilson, promised to forge a new Britain in the "white heat of technological revolution", his words sent a tremor of anticipation through the research community. The election of a government explicitly committed to science and ...
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    Nature 386 (1997), S. 327-329 
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    Notes: [Auszug] In forests on hillsides, the trunks of the understorey trees may lean outwards from the slope, although the canopy trees are more vertical (Fig. la, overleaf). Two main theories have been put forward to explain this phenomenon - that it is caused either by the wind or by disturbances such as ...
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    Nature 386 (1997), S. 332-332 
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    Notes: [Auszug] The majority of deep-sea species are mud eaters; some are of gigantic size; some are armed with peculiar tactile, prehensile, and alluring organs; some are totally blind, whilst* others have large eyes and are provided with a kind of dark lantern for the emission of phosphorescent light. The ...
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    Nature 386 (1997), S. 319-319 
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    Notes: [Auszug] Sir- In recent months, Nature has brought us two highly imaginative alternatives to conventional fossil fuel. The first, where petrol is produced by "adding leaves and bark extracts from a native herb to tap water," has tragically turned out to be a hoax (Nature 383,112 &384,106; 1996). Let's ...
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    Nature 386 (1997), S. 320-320 
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    Notes: [Auszug] Sir - I read with interest the News story about the issues raised by Japan's demography, showing that a dramatic increase in population age is being accompanied by a decrease in the number of financially productive individuals (Nature 385,379; 1997). The extrapolations that can be made from ...
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    Notes: [Auszug] Sir - Your recent News story on marijuana (Nature 385,756; 1997) was factual and objective but, as in most of the other media coverage of the subject of smoked cannabis versus oral A-9-tetrahydrocannabinol (THC) (Marinol), an important point has been omitted. The cannabis plant is a complex ...
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    Nature 386 (1997), S. 321-322 
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    Notes: [Auszug] Every columnist in the English-speaking press seems to have had a say about last December's resolution by the governing board of the Oakland Unified School District in California. The board's proposal was to recognize the native tongue of most of its pupils as a language, which triggered an ...
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    Nature 386 (1997), S. 328-328 
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    Notes: [Auszug] A new set of maps, released by the US Geological Survey, show the latest estimates of earthquake shaking hazards in the United States. Along with the well-known hazards in California, they reveal an increased awareness of the threat of earthquakes in the Pacific Northwest (associated with the ...
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    Nature 386 (1997), S. 331-331 
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    Notes: [Auszug] Astronomers first detected high-speed plasma outflows from quasars in the late 1960s, just a few years after the quasars themselves were recognized as extremely distant and luminous objects. Since then we have grappled with basic questions about these winds. What drives them? What is their ...
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    Nature 386 (1997), S. 333-333 
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    Notes: [Auszug] Compulsory games in British schools are declining. A public discussion of the matter a few years ago showed a cttridiis distribution. Some adults recalled football and other sports as the high point of their school lives; others remembered them with loathing and rage Daedalus notettiecja exercise ...
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    Nature 386 (1997), S. 336-337 
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    Notes: [Auszug] Gram-positive bacteria lack lipopolysaccha-ride (LPS), an integral component of the outer membrane of Gram-negative bacteria, but their presence in tissues triggers inflammatory responses similar to LPS in terms of tumour-necrosis factor-a (TNF-a) and inter-leukin-1 production, cardiovascular ...
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    Nature 386 (1997), S. 338-338 
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    Notes: [Auszug] Long-term potentiation (LTP) is often considered to be a cellular correlate of learning. During LTP induction in the CA1 region of the hippocampus, nitric oxide (NO) synthesized in the dendrites of pyramidal cells may carry retrograde signals from the post-synapic to the presynaptic terminals1'2. ...
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    Nature 386 (1997), S. 342-342 
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    Notes: [Auszug] The Eleventh Plague: The Politics of Biological and Chemical Warfare by Leonard A. Cole W.H. Freeman: 1996. Pp. 284. $22.95, £24.95 Leonard Cole ranks chemical and biological warfare as the "eleventh plague". The first ten, described in the book of Exodus, were reputedly ...
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    Nature 386 (1997), S. 342-342 
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    Notes: [Auszug] The surgeon Sir Roy Calne performed the first liver transplant in Europe. But he is an artist too, and has painted transplant patients and fellow surgeons. Many of these paintings are reproduced in his book Aft, Surgery and Transplantation (William & Wilkins Europe, £45), along with other ...
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    Notes: [Auszug] Topoisomerases change the degree of superhelicity, catenation and knotting of topologically closed DNA molecules. They are classified into type I and II according to the nature of this transient break, single- or double-stranded, respectively1. Type I topoisomerases, which are mostly ...
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    Nature 386 (1997), S. 203-203 
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    Notes: [Auszug] [WASHINGTON] The US Mission to Planet Earth (MTPE), which includes a multibil-lion-dollar series of satellites to observe the planet, oceans and atmosphere, is undergoing yet another major review that may complete the programme's evolution from the use of large, centralized spacecraft to a smaller ...
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    Notes: [Auszug] [LONDON & MUNICH] The European Commission is coming under pressure from member states of the European Union (EU) to impose tighter constraints on research projects to be funded under the fifth Framework programme (FP5), and to reduce its proposed emphasis on untargeted generic and basic ...
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    Notes: [Auszug] The apical ectodermal ridge of the vertebrate limb bud lies at the junction of the dorsal and ventral ectoderm and directs patterning of the growing limb. Its formation is directed by the boundary between cells that do and cells that do not express the gene Radical fringe. This is similar to ...
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    Nature 386 (1997), S. 382-385 
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    Notes: [Auszug] North Atlantic Deep Water possesses a distinct physical, chemical and isotopic signature (see, for example, refs 4, 13-15). In particular, the sources of NADW impart an extremely unradiogenic Nd isotope composition (eNd = - 13.5 ± 0.5 (ref. 15), where eNd is the measured 143Nd/144Nd ratio ...
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    Nature 386 (1997), S. 392-395 
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    Notes: [Auszug] A general strategy for learning is to divide a complex task into simpler subtasks and learn each subtask with a separate module. This strategy has been formalized into a computational model of learning known as the mixture of experts1, in which a set of expert modules each learn one of the subtasks ...
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    Nature 386 (1997), S. 231-231 
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    Notes: [Auszug] In many taxa, parents compensate for the overproduction of young by conferring vital advantages on certain offspring, enabling them to out-compete their siblings when resources are scarce1'2. With birds, the competitive advantage is usually related to the age of chicks, which varies because of ...
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    Notes: [Auszug] Alatalo et al. in their Scientific Correspondence1 suggest that an increase in published heritability estimates since 1988 results from a paradigm shift, increasing willingness to publish such estimates based on small sample sizes. But there have been several changes in the types of studies ...
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    Notes: [Auszug] [WASHINGTON] Several influential US congressmen last week urged their colleagues to take a calmer approach to human cloning, after an initial burst of support for restrictive legislation that followed last month's announcement that a sheep had been cloned. But at the end of the week, the ...
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    Notes: [Auszug] [SAN DIEGO] The US Department of Veterans' Affairs is conducting an inquiry into whether the absence of documentation on key experiments leading to the publication of research carried out at a centre affiliated to Harvard Medical School should be treated as scientific misconduct. Although ...
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    Nature 386 (1997), S. 208-208 
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    Notes: [Auszug] [ROME] Italy is giving its research agencies a unique opportunity to reform their notoriously bureaucratic management structures - the bane of scientists for decades - and to develop more effective ways of allocating research funds. The Italian parliament agreed last week that the government ...
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    Notes: [Auszug] The primary role of the X-inactivation centre is to initiate X-chromosome inactivation, leading to a spread of inactivation up and down the X chromosome2'3. In addition, the Xic senses whether the cell contains one or more X chromosomes and therefore whether or not it should initiate X ...
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] X inactivation consists of several steps, including the counting of X chromosomes2'6, commitment of all but one of these to inactivation1, initiation at Xzc4'6, induction of Xist expression7"9, propagation of Xist RNA along the X chromosome3, and establishment and maintenance of heterochromatin ...
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    Nature 386 (1997), S. 296-299 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We used the yeast two-hybrid system to identify proteins that interact with p38. Because active kinase-substrate interactions may be transient, we used a kinase-inactive mutant of p38 to favour the formation of stable protein-protein complexes5. We used as targets two constructs of p38 that were ...
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  • 92
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    Nature 386 (1997), S. 111-111 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir- Donald Ort (Nature 385,290; 1997) argues that" [t]he interspecific genetic modification of foods is not inherently new" and that "the more the focus is kept on safety of the product for humans and the environment, with decisions being made on the basis of the soundest scientific findings ...
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    Nature 386 (1997), S. 113-113 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir- I was disappointed to read that you feel that, as South Africa seeks to reform its science base, it would be a mistake if the research of the Atomic Energy Corporation (AEC) were to escape the knife (Nature 384, 1; 1996). In 1990 the corporation put in place, of its own volition, a ...
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    Nature 386 (1997), S. 114-114 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir- Several of the assertions made by Paul Bahn in his review of American Beginnings (Nature385,128-129; 1997) are debatable, and as editor of that book I should like to comment on them. I do not know whether there is a consensus about when the first people entered America. There are ...
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    Nature 386 (1997), S. 122-123 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Nowhere in the brain is the connection between body and mind so conspicuous as in the parietal lobes: damage to the parietal cortex disrupts awareness of one's body and the space that it inhabits1'2. Experiments in monkeys indicate that the neural circuits responsible for spatial perception ...
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Rapid macromolecular synthesis is required for the establishment of long-term neuronal plasticity3'4. To identify molecules that are involved in this process, we and others have used differential cloning strategies to identify genes that are rapidly induced in neurons of the hippocampus and cortex ...
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  • 97
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    Nature 386 (1997), S. 100-100 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [WASHINGTON] A bipartisan task force is to be set up in the House of Representatives to conduct a wide-ranging review of all aspects of US science policy. The review, due for completion by the end of next year, will be led by Vernon Ehlers (Republican, Michigan), the vice-chair of the Science ...
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    Nature 386 (1997), S. 102-102 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [SAN FRANCISCO] California's environmental research agency was accused last week of diluting and delaying scientific reports that may have led to stricter regulations on potentially dangerous chemicals. The accusations were made by university scientists, former employees and environmental activists ...
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    Nature 386 (1997), S. 107-107 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The State of World Fisheries the latest report from the United Nations Food and Agriculture Organization in Rome, could make even the most eager fish gourmet think again before placing their next order. More than two-thirds of the world's species -including favourites such as cod, lobster, prawn ...
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    Nature 386 (1997), S. 112-112 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir- Shinji Yokoyama's letter reveals the perception of a researcher associated with the Japanese grant system (Nature 384, 402-403; 1996). But your readers should be told of recent reforms and the need for more resources. (I write as chairman of the committee on grants-in-aid for scientific ...
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