ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Lipids
  • American Association for the Advancement of Science (AAAS)  (4)
  • American Chemical Society  (1)
  • 1
    Publication Date: 2022-05-27
    Description: © The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Gosselin, K. M., Nelson, R. K., Spivak, A. C., Sylva, S. P., Van Mooy, B. A. S., Aeppli, C., Sharpless, C. M., O’Neil, G. W., Arrington, E. C., Reddy, C. M., & Valentine, D. L. Production of two highly abundant 2-methyl-branched fatty acids by blooms of the globally significant marine cyanobacteria Trichodesmium erythraeum. ACS Omega, 6(35), (2021): 22803–22810, https://doi.org/10.1021/acsomega.1c03196.
    Description: The bloom-forming cyanobacteria Trichodesmium contribute up to 30% to the total fixed nitrogen in the global oceans and thereby drive substantial productivity. On an expedition in the Gulf of Mexico, we observed and sampled surface slicks, some of which included dense blooms of Trichodesmium erythraeum. These bloom samples contained abundant and atypical free fatty acids, identified here as 2-methyldecanoic acid and 2-methyldodecanoic acid. The high abundance and unusual branching pattern of these compounds suggest that they may play a specific role in this globally important organism.
    Description: This work was funded with grants from the National Science Foundation grants OCE-1333148, OCE-1333162, and OCE-1756254 and the Woods Hole Oceanographic Institution (IR&D). GCxGC analysis made possible by WHOI’s Investment in Science Fund.
    Keywords: Lipids ; Alkyls ; Bacteria ; Genetics ; Chromatography
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    Publication Date: 2008-10-18
    Description: Conventional magnetic resonance methods that provide interior temperature profiles, which find use in clinical applications such as hyperthermic therapy, can develop inaccuracies caused by the inherently inhomogeneous magnetic field within tissues or by probe dynamics, and work poorly in important applications such as fatty tissues. We present a magnetic resonance method that is suitable for imaging temperature in a wide range of environments. It uses the inherently sharp resonances of intermolecular zero-quantum coherences, in this case flipping up a water spin while flipping down a nearby fat spin. We show that this method can rapidly and accurately assign temperatures in vivo on an absolute scale.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080759/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080759/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Galiana, Gigi -- Branca, Rosa T -- Jenista, Elizabeth R -- Warren, Warren S -- EB2122/EB/NIBIB NIH HHS/ -- EB5979/EB/NIBIB NIH HHS/ -- R01 EB002122/EB/NIBIB NIH HHS/ -- R01 EB002122-22A2/EB/NIBIB NIH HHS/ -- New York, N.Y. -- Science. 2008 Oct 17;322(5900):421-4. doi: 10.1126/science.1163242.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18927389" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Body Temperature ; Lipids ; Magnetic Resonance Imaging/*methods ; Mice ; Mice, Obese ; *Temperature ; Water
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    facet.materialart.
    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-02-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hla, Timothy -- Im, Dong-Soon -- New York, N.Y. -- Science. 2009 Feb 13;323(5916):883-4. doi: 10.1126/science.1170009.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Vascular Biology, University of Connecticut Health Center, Farmington, CT 06030, USA. hla@nso2.uchc.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19213902" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Transport ; Carrier Proteins/*physiology ; Chemotaxis/*physiology ; Drosophila Proteins/*physiology ; Drosophila melanogaster ; Germ Cells/physiology ; Heart/embryology ; Lipids ; Lysophospholipids/metabolism ; Membrane Proteins/*physiology ; P-Glycoproteins/*physiology ; Sphingosine/analogs & derivatives/metabolism ; Zebrafish ; Zebrafish Proteins/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Publication Date: 2010-12-04
    Description: Optical imaging in vivo with molecular specificity is important in biomedicine because of its high spatial resolution and sensitivity compared with magnetic resonance imaging. Stimulated Raman scattering (SRS) microscopy allows highly sensitive optical imaging based on vibrational spectroscopy without adding toxic or perturbative labels. However, SRS imaging in living animals and humans has not been feasible because light cannot be collected through thick tissues, and motion-blur arises from slow imaging based on backscattered light. In this work, we enable in vivo SRS imaging by substantially enhancing the collection of the backscattered signal and increasing the imaging speed by three orders of magnitude to video rate. This approach allows label-free in vivo imaging of water, lipid, and protein in skin and mapping of penetration pathways of topically applied drugs in mice and humans.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462359/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462359/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Saar, Brian G -- Freudiger, Christian W -- Reichman, Jay -- Stanley, C Michael -- Holtom, Gary R -- Xie, X Sunney -- 1R01EB010244-01/EB/NIBIB NIH HHS/ -- R01 EB010244/EB/NIBIB NIH HHS/ -- R01 EB010244-02/EB/NIBIB NIH HHS/ -- New York, N.Y. -- Science. 2010 Dec 3;330(6009):1368-70. doi: 10.1126/science.1197236.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21127249" target="_blank"〉PubMed〈/a〉
    Keywords: Administration, Cutaneous ; Animals ; Capillaries ; Dimethyl Sulfoxide/administration & dosage/pharmacokinetics ; Epidermis/chemistry/metabolism ; Erythrocytes/physiology ; Humans ; Imaging, Three-Dimensional ; Light ; Lipids ; Male ; Mice ; Mice, Nude ; Molecular Imaging/*methods ; Skin/blood supply/*chemistry/*metabolism ; Spectrum Analysis, Raman/*methods ; Time Factors ; Vitamin A/administration & dosage/pharmacokinetics ; Water
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    Publication Date: 2002-06-29
    Description: Efforts to influence the biology of blood vessels by gene delivery have been hampered by a lack of targeting vectors specific for endothelial cells in diseased tissues. Here we show that a cationic nanoparticle (NP) coupled to an integrin alphavbeta3-targeting ligand can deliver genes selectively to angiogenic blood vessels in tumor-bearing mice. The therapeutic efficacy of this approach was tested by generating NPs conjugated to a mutant Raf gene, ATPmu-Raf, which blocks endothelial signaling and angiogenesis in response to multiple growth factors. Systemic injection of the NP into mice resulted in apoptosis of the tumor-associated endothelium, ultimately leading to tumor cell apoptosis and sustained regression of established primary and metastatic tumors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hood, John D -- Bednarski, Mark -- Frausto, Ricardo -- Guccione, Samira -- Reisfeld, Ralph A -- Xiang, Rong -- Cheresh, David A -- CA50286/CA/NCI NIH HHS/ -- P41 RR09784/RR/NCRR NIH HHS/ -- T32 CA09696/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2002 Jun 28;296(5577):2404-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12089446" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphate/metabolism ; Animals ; Apoptosis ; Cations ; Endothelium, Vascular/cytology/metabolism/pathology ; Gene Targeting ; Gene Transfer Techniques ; Genetic Therapy/*methods ; Genetic Vectors ; Humans ; In Situ Nick-End Labeling ; Ligands ; Lipids ; Melanoma, Experimental/blood supply/pathology/therapy ; Mice ; Mice, Inbred BALB C ; Mutation ; *Nanotechnology ; Neoplasm Metastasis ; Neoplasm Transplantation ; Neoplasms, Experimental/blood supply/pathology/*therapy ; Neovascularization, Pathologic/pathology/*therapy ; Proto-Oncogene Proteins c-raf/*genetics/metabolism ; Random Allocation ; Receptors, Vitronectin/*metabolism ; Tumor Cells, Cultured
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...