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  • Humans  (2,769)
  • Fisheries
  • Magnetism
  • Mice
  • 1995-1999  (3,278)
  • 1
    ISSN: 1573-0832
    Keywords: Cryptococcus ; Immunity ; Immunohistology ; Meningoencephalitis ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract An immunohistological study of L3T4(CD4)+ and LYT-2(CD8)+ lymphocytes, Mac-1(CD11b)+ monocytes and granulocytes in experimental murine cryptococcal meningoencephalitis was conducted. To assess the concomitant inflammatory reaction in an extracerebral site, livers were examined in parallel. Mice were infected i.v. withCryptococcus neoformans, group A/D, and organs were examined immunohistologically for CD4-, CD8- and monocyteand granulocyte-specific CD11b-phenotypic leukocytes over a period of 60 days. Intracerebrally, agglomerations of cryptococci formed pseudocysts that were surrounded by CD4+ and CD8+ lymphocytes at the end of the second week post-infection, followed by the invasion of monocytes and granulocytes into the lesions. After the fourth week post-infection, most of the invaded lesions were transformed into glious scars. Meningitis was usually marked and showed a homogenous distribution of CD4-, CD8- and CD11b-phenotypic cells, with a predominance of monocytes and CD4+ lymphocytes. Inflammatory infiltrates in the liver were found already 4 days post-infection. CD4+ lymphocytes and monocytes were distributed homogenously in the infiltrates, with a lower number of CD8+ lymphocytes being located rather in the periphery of the infiltrates. Comparing leukocyte kinetics in brain and liver, an important observation was the delayed immigration of immune cells at the intracerebral cryptococcal lesions as compared with the liver, and the different migration patterns of T-lymphocyte subgroups and macrophages. These results suggest that there are differential leukocyte migration patterns in the liver and brain following disseminated cryptococcosis. The immunological aspects of the observed leukocyte kinetics are discussed.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of biomedical science 2 (1995), S. 146-153 
    ISSN: 1423-0127
    Keywords: Transgene ; Mice ; Embryogenesis ; HIV ; Toxicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The likelihood that expression of a foreign gene in a mammalian cell is deleterious to viability is confronted whenever novel transgenic animals are made. A pathological response to transgene expression is even desired in transgenic mouse models of human disease. The derivation of HIV-transgenic mice in our laboratory using multiple recombinant forms of an HIV provirus has resulted in mixed success best explained by the variable toxicity of the different transgenes. Employing a standardized approach to pronuclear injections, experimental variation amongst recombinant HIV transgenes was documented in terms of the percentage of pregnancies following embryo transfer into pseudopregnant mice and the percentage of transplanted embryos leading to term births in these pregnant females (giving rise to an index of birth success, SI). Results compiled over 5 years suggested that the SI reflected transgene toxicity, in this case of HIV gene products early in embryogenesis. These observations have guided the design of productive transgenes for mouse models of HIV-related diseases and may be generally applicable in transgenesis.
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  • 3
    ISSN: 1432-1009
    Keywords: Reservoir ; Fisheries ; Breeding and wintering waterbirds ; Raising water levels ; Habitat change
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract A new, higher dam was installed at Kerkini Reservoir in 1982, causing habitat and landscape disruption. A decrease in the area of grassland and shallow water areas, the rapid disappearance of reedbeds, the appearance of beds ofNymphaea, and the disappearance of half the forest area were all observed between 1982 and 1991. With the new hydrological regime, a lacustrine system was created, with an extensive, rather deep (4–8 m), pelagic zone favorable for the development of coarse fish species throughout the year. After 1982, an increase in fishing effort and a change in the relative abundance of fish species in the catch, including the disappearance of eels and wels, were observed. The impact of the rise in the water level of breeding aquatic birds led to a general decline in species typical of marshy habitats in favor of species preferring deeper open water habitats. A decrease was recorded in bird species that feed largely on invertebrates and to a lesser extent fish (e.g., glossy ibis) and that require extensive shallow feeding areas. There was a decline in geese, whose nests were regularly flooded, and a major increase in piscivorous birds, particularly diving birds (e.g., cormorants), which prefer deeper open water and benefitted directly from the large increase in coarse fish biomass. The disappearance of birds breeding in flooded meadows (e.g., black-winged stilts) and of those restricted to reedbeds (e.g., marsh harrier) occurred from 1983. Over the same period, the changes in populations of wintering birds at Kerkini were different from those occurring in other wetlands in northern Greece. The changes recorded in the populations of wintering birds at Kerkini did not therefore result from overall regional trends but from the major habitat modifications that occurred to this wetland. As for breeding birds, strictly piscivorous species increased greatly as a result of the increased availability of fish, but also due to the appearance of many suitable night roosting sites (flooded trees) and to the great increase in the area of open water greater than 2 m deep. Today, Kerkini has become the most important breeding site in Greece for a majority of colonial waterbirds. In contrast, wintering shorebirds practically disappeared. The many changes recorded in the status of breeding and wintering birds at Kerkini can mostly be explained by the changes that occurred in the functioning of the ecosystem and in the habitat structure following the inauguration of the new hydrological regime. These changes did not all occur at the same time: some were immediate and others required a delay before they could be detected.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Environmental management 20 (1996), S. 523-539 
    ISSN: 1432-1009
    Keywords: Water control ; Floodplain ; Fisheries ; Bangladesh ; Chandpur
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Bangladesh is a very flat delta built up by the Ganges—Brahmaputra—Meghna/Barak river systems. Because of its geographical location, floods cause huge destruction of lives and properties almost every year. Water control programs have been undertaken to enhance development through mitigating the threat of disasters. This structural approach to flood hazard has severely affected floodplain fisheries that supply the major share of protein to rural Bangladesh, as exemplified by the Chandpur Irrigation Project. Although the regulated environment of the Chandpur project has become favorable for closed-water cultured fish farming, the natural open-water fishery loss has been substantial. Results from research show that fish yields were better under preproject conditions. Under project conditions per capita fish consumption has dropped significantly, and the price of fish has risen beyond the means of the poor people, so that fish protein in the diet of poor people is gradually declining. Bangladesh is planning to expand water control facilities to the remaining flood-prone areas in the next 15–20 years. This will cause further loss of floodplain fisheries. If prices for closed-water fish remain beyond the buying power of the poor, alternative sources of cheap protein will be required.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 91 (1995), S. 340-345 
    ISSN: 1432-2242
    Keywords: Selection index ; Restricted index ; Fat ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The objective of this study was to determine if low secondary selection differentials, caused by selecting within full-sib families, may have accounted for the failure of an intended restricted selection index to reduce epididymal fat pad weight (EF) without changing body weight (BW) in mice. Replicate lines that had been selected within full-sib families for high (HE) or low (LE) EF, while holding BW constant, were crossed. After two generations of random mating, two replicates were sampled and selection initiated for the same restricted index criteria except that mass selection was used to increase the selection differentials. In both phases of selection the HE restricted index selection, designed to increase EF without altering BW, was in agreement with expectation. In contrast, the LE index, designed to decrease EF without changing BW, did not agree with theory since BW increased while EF decreased only slightly. Therefore, reduced selection differentials could not explain the deviation from theory. A possible explanation may reside in the restricted selection index being more sensitive to changes in genetic parameters due to shifts in gene frequency as a consequence of the selection applied. However, linkage disequilibrium and genetic drift can not be ruled out as contributing factors to the asymmetry of response.
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  • 6
    ISSN: 1432-0878
    Keywords: Key words: Skeletal muscle ; Regeneration ; Ageing ; Strain-specific muscle precursor replication ; Autoradiography ; Mice ; BALBc (SJL/J)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The patterns of skeletal muscle precursor cell replication after crush injury were compared by the use of autoradiographic techniques, in young (4-week-old) and old (39-week-old) BALBc and SJL/J mice. Similar comparisons were made between cut and crush lesions in old BALBc muscle. Muscle precursor cell replication commenced at 18–24 h after injury in both young and old muscles from both strains of mice. In young BALBc muscle the peak of myogenic activity at 60 h was 36 h earlier than in old mice. SJL/J muscle responded more rapidly than did BALBc: in young SJL/J the peak myogenic activity was at 46 h (14 h earlier than in young BALBc muscle), and in old SJL/J muscle the peak activity at 72 h was 24 h earlier than in old BALBc muscle. In all mice (both young and old) myogenic cell replication was substantially reduced by 120 h after injury. A comparison of the timing of muscle precursor cell replication in cut and crush lesions in old BALBc mice revealed a more rapid response in the cut lesion; this difference between the lesions is comparable with data from identical lesions in 6–8-week-old BALBc mice (McGeachie and Grounds 1987). However, the peak of myogenic replication in the older mice in the present study was some 26–36 h later than in the younger 6–8-week-old mice. These experiments show that, whilst muscle precursor cell replication commences at approximately the same time (about 24 h) after injury in young and old mice, the peak level of activity is delayed by some 24–36 h in old mice. In addition, the SJL/J mouse strain responds more rapidly and prolifically to muscle injury than does the BALBc strain.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Behavior genetics 26 (1996), S. 463-470 
    ISSN: 1573-3297
    Keywords: Mice ; agonistic behavior ; aggression ; homogeneous set ; standard tester ; social behavior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Though social behavior has not been overlooked by behavior geneticists, the number of studies is small when compared to those on individual traits. One reason for the neglect may be the difficulty of making connections between genes and social behaviors, which by definition involve the interaction of two or more organisms. Fuller and Hahn (1976) addressed this issue and described three means of establishing social groups that would facilitate genetic analysis. We survey the literature on agonistic behavior in mice from 1976 through 1994 and describe interesting uses of those three methods. One of those methods (the standard tester design) often employs a “noninteractive” social partner. We present data showing that the standard tester design may be more valuable when using an evocative and interactive standard tester.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Environmental biology of fishes 45 (1996), S. 219-235 
    ISSN: 1573-5133
    Keywords: Ecology ; Behaviour ; Evolution ; Cichlids ; Fisheries ; Conservation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Ecological conditions in tropical lacustrine systems are considered by focusing on the evolution, maintenance, exploitation and vulnerability of fish communities in the African Great Lakes. The exceptionally high biodiversities in the littoral/sublittoral zones of the very ancient, deep, clear, permanently stratified rift lakes Tanganyika and Malawi, are contrasted with the simpler systems in their pelagic zones, also with biodiversity in the much younger, shallower Victoria, the world's largest tropical lake.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Animal cognition 1 (1998), S. 25-35 
    ISSN: 1435-9456
    Keywords: Key words Shape from shading ; Visual search ; Texture segregation ; Chimpanzees ; Humans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The perception of shape from shading was tested in two chimpanzees (Pan troglodytes) and five humans (Homo sapiens), using visual search tasks. Subjects were required to select and touch an odd item (target) from among uniform distractors. Humans found the target faster when shading was vertical than when it was horizontal, consistent with results of previous research. Both chimpanzees showed the opposite pattern: they found the target faster when shading was horizontal. The same difference in response was found in texture segregation tasks. This difference between the species could not be explained by head rotation or head shift parallel to the surface of the monitor. Furthermore, when the shaded shape was changed from a circle to a square, or the shading type was changed from gradual to stepwise, the difference in performance between vertical and horizontal shading disappeared in chimpanzees, but persisted in humans. These results suggest that chimpanzees process shading information in a different way from humans.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Environmental biology of fishes 43 (1995), S. 381-391 
    ISSN: 1573-5133
    Keywords: Fisheries ; Irrigation ; Reproductive seasonality ; Sarotherodon galilaeus ; Species richness ; Water quality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis A preliminary study of the ecology and commercial fish catches was carried out in the Toho-Todougba, Ahouangan and Dati lakes (1500 ha) in southern Benin (West Africa) over a period of 18 consecutive months. Water quality, species richness, and the reproductive biology of the dominant species, Sarotherodon galilaeus, were examined. Unlike Lagoon Toho-Todougba, lakes Ahouangan and Dati are less favourable for fish production because of their high total iron content and their relative low pH. The study revealed the existence of 19 species belonging to eleven (11) families: 16 species in Lagoon Toho-Todougba,12 in Lake Ahouangan, and 7 in Lake Dati. Lakes Ahouangan and Dati had a relatively high faunal similarity whereas Lagoon Toho-Todougba exhibited a relatively low faunal similarity with the former systems. In Lagoon Toho-Todougba, six cichlid species were the most important component of the fishery: Sarotherodon galilaeus, Tilapia guineensis, T. zillii, T. mariae, Chromidotilapia guntheri, Hemichromis fasciatus. Three catfish species Chrysichthys auratus, Clarias agboyiensis, and Clarias lazera were harvested in low abundances. Some other fish, such as Polypterus senegalus senegalus, Protopterus annectens and Heterotis niloticus were captured sporadically, with H. niloticus appearing more consistently in catches than the others. Although not abundant, Gymnarchus niloticus and the African pike, Hepsetus odoe, were almost always present in the catches. Ctenopoma kingsleyae appeared only in Ahouangan. Some predatory species, such as Notopterus afer and Xenomystus nigri, are encountered only in lakes Ahouangan and Dati. In Lagoon Toho-Todougba, Sarotherodon galilaeus had a sex ratio (♂: ♀) of 0.49:1, and size at maturation was estimated as 12.3 cm TL. The spawning period extended from May to September with the peak occurring in July. Fecundity was correlated to log-body length (r = 0.74) and log-body weight (r = 0.76). Fish catches were estimated at 389 kg ha−1 year−1; about 73% of which was Sarotherodon galilaeus. The overexploitation of juvenile fish and the use of this lagoon for the irrigation of palm tree plantations have reduced fish recruitment and mean size.
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