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  • Articles  (13,374)
  • American Association for the Advancement of Science (AAAS)  (8,856)
  • Cell Press  (2,437)
  • Oxford University Press  (1,780)
  • American Association of Petroleum Geologists (AAPG)
  • Emerald
  • 1995-1999  (13,374)
  • Chemistry and Pharmacology  (12,496)
  • Process Engineering, Biotechnology, Nutrition Technology  (957)
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  • Articles  (13,374)
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  • 1
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 24-28 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A three-year consumer research programme, using both qualitative and quantitative techniques, was undertaken to assess whether additional voluntary nutrition information for calories and fat would aid consumers' ability to use the nutrition information that is given on food packs. A variety of label formats was investigated. The research established that providing information for calories and fat per serving, either separately from the nutrition panel or highlighted within the nutrition panel, and providing Guideline Daily Amounts (GDAs) for calories and fat helped to make the nutrition information more accessible to consumers. GDAs were felt by consumers to be new and useful information. The research findings were developed into voluntary industry guidelines by an IGD working group consisting of representatives of manufacturers, retailers, consumer organizations, nutrition scientists and government. The guidelines represent best practice for industry.
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  • 2
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The purpose of this study was to determine body composition, energy balance and tendencies towards eating disorders of female competitive athletes in two countries, USA and Greece. Data were collected using similar methodology in both countries during the non-competitive (training) and the competitive seasons. Forty-two athletes and 11 controls in the USA and 35 athletes and ten controls in Greece participated in the study. Comparison of the results between the countries showed that US athletes weighed more than Greek athletes but there was no significant difference in the percentage of body fat between the two groups. No significant differences were found in the energy intakes between athletes in either country. Athletes appeared to be in negative energy balance (-380 to -580 kcals daily) in both seasons, in both countries.
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  • 3
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 12-18 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A survey of 12 residential homes assessed the nutritional balance of the meals selected and consumed by the elderly residents. With the increasing age of the population and the demand for professional care there is an increasing pressure on the professional caterer and carer to meet the nutritional needs of those in their care. However the ongoing concern over the safety of various foods and the requirement for residential homes to remain within budget can have an impact on the food offered to and consumed by the elderly person. The results show a general satisfaction by the consumer with the food supplied but the research indicates that the meals are not generally nutritionally balanced. The overall concern of the providers is to remain within budget and any nutritional balance of meals is obtained more by accident than as a planned policy. If this is an indication of the situation in Northern Ireland there is the possibility that throughout the United Kingdom there may be similar widespread imbalance in the nutritional provision to the older members of the population.
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  • 4
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 37-41 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A good relationship between the hospitality industry and environmental health officers is seen as essential if food poisoning statistics are to be improved in the future. A questionnaire issued to both parties indicates that there are still areas of disagreement which need to be bridged if progress in food safety is to be made.
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  • 5
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 78-80 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: With changes in the curriculum, science breakthroughs, consumer demands and the Government's recent Green Paper on Our Healthier Nation, the British Nutrition Foundation's National Nutrition Education Conference entitled "Emerging issues for the next millennium" informed delegates about emerging issues in nutrition and education.
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  • 6
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 144-148 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The role of diet in contributing to the incidence of coronary heart disease, cancer and other common Western diseases is attracting increasing attention. Foods which provide different biologically active compounds, such as phyto-oestrogens, have been extensively studied and epidemiological evidence suggests that populations consuming a diet high in phyto-oestrogens have a lower risk of these diseases. This paper reviews some of the key studies on soy isoflavones which suggest that the incorporation of soy protein into the British diet may offer important health benefits. Non-steroidal dietary oestrogens are found in high concentrations in the traditional diets of the Far East, and by vegans who consume large amounts of soy protein. Consumption of isoflavones across Asia varies considerably and it is estimated that between 25 to 45mg of isoflavones is consumed daily, compared to as little as 5mg daily in Western countries. It is well established that modification of dietary fat, especially saturated fat, soluble fibre and total calories have a role in coronary heart disease risk. In a meta-analysis of 38 controlled trials on soy proteins, it was concluded that significant reductions in serum and total LDL cholesterol could be achieved. A wide range of epidemiological data shows strong correlations between a diet high in soy protein and vegetables and a reduced risk of breast cancer. The incidence of osteoporosis in Japanese women is significantly lower than in Western women and dietary factors such as soy protein intake may be important in sustaining this protection.
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  • 7
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 187-193 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The links between diet, bacteria and colonic cancer are examined in this article. Studies suggest that high intakes of fat and protein are associated with elevated risk of colonic cancer whereas cereals, fruits and vegetables seem to be protective. A further aspect considered in relation to this type of cancer is metabolism by gut bacteria. Probiotics, prebiotics and synbiotics are presented as ways of stimulating the activities, certain gut flora and the use of "functional foods" is also discussed.
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  • 8
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 219-224 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A new National Diet and Nutrition Survey was published in October 1998, by the Ministry of Agriculture, Fisheries and Food and the Department of Health, which reported on the dietary intake and nutritional status of people over 65 years of age in the UK. This survey provided data on 1,275 free-living people and 412 people in residential care. Along with the information on diet and nutritional status are data on anthropometric and biochemical parameters. A second related survey looked at dental health in this age group. The key findings of these surveys and the public health implications for older people are discussed.
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  • 9
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 178-184 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Antibiotics are used in animals to cure disease and prevent suffering. Bacterial populations in animals which are exposed to these antibiotics may be selected for resistance. There is a concern that spread of these bacteria in the food chain to humans may result in the establishment of antibiotic resistant bacteria in people which will prove difficult or impossible to treat with conventional drugs. It is clear that antibiotics must be used carefully to reduce the development of resistance and that steps should be taken to reduce the transfer of bacteria from animals to man.
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  • 10
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    Nutrition & food science 99 (1999), S. 192-199 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article focuses on the dietary requirements of people with Diabetes Mellitus, both insulin dependent and non-insulin dependent. It is one disorder where good dietary management can benefit control, well being and avoid complications. The guidelines for dietary intake for those with Diabetes Mellitus both past and present are given. The recommended intake of carbohydrate, fruit and vegetables, sugar, protein, fat, salt and alcohol are also discussed. The study itself focuses on the organisations involved in producing diet sheets for people with Diabetes Mellitus. The article also gives information on how to obtain such publications.
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  • 11
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 229-238 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Few studies have concentrated on the food choices of young people and the potential influences, yet the food choices established in these early years can determine the diet and quality of health in later life. This study investigates the diet and food choices of 9-17-year olds in Northern Ireland and considers the potential effects of age, gender and socio-economic grouping. A range of research methods was implemented including observations, questionnaires and diet based case studies. The observations, in five schools, indicated the types of foods being chosen whilst the questionnaires further investigated this initial information along with other factors, to obtain more detailed data. A total of 764 questionnaires were administered to young people and 516 to parents to facilitate comparison. In-depth diet based case studies also took place evaluating the diets of 14 young people. The research indicated that this group have a diet which continues to cause concern.
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  • 12
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 270-277 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Outlines the numerous messages sent to consumers regarding healthy eating practices and indicates the problems involved in determining whether or not the British consumer has adopted a nutritious and healthy diet. Research was undertaken which measured individuals' involvement in healthy eating issues and related this to several demographic characteristics. The research indicates some variation in involvement in healthy eating according to demographic variables but the results were not statistically significant. Group discussions were also conducted which confirmed that the healthy eating messages were widely received and understood; however, there was some confusion over their content, scepticism regarding the veracity and motivation of some sources and a growing resentment of boring and puritanical themes. In the future care must be taken to produce clear, simple and positive healthy eating messages to the public if trends towards a more nutritious diet are to continue.
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  • 13
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 281-284 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Much of the debate surrounding genetic modification has centred on food product ingredients, in particular soya derivatives, and the supposed inability to segregate GM from non-GM soybeans. Protein Technologies International has, however, implemented a system, Identity Preservation, which ensures the delivery of non-GM soy protein to its customers. The system covers seeds, on-farm storage, planting, growing and harvesting, transportation, processing and distribution, with independent third-party verification. It is, believes the company, a way of ensuring that consumers can obtain the health benefits of soy protein consumption even if they are actively avoiding GM ingredients.
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  • 14
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    Nutrition & food science 99 (1999), S. 140-143 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: foodlink's National Food Safety Week provides a focus for communicating messages designed to help people understand and initiate the basic precautions which can be taken to reduce the risk of food poisoning and in the process provide fun and entertainment for thousands throughout the UK. There were over 100,000 reported cases of food poisoning last year and there has been much speculation recently that many more cases go unreported. National Food Safety Week provides the tools both to raise awareness of the problem and to provide the answers in a fun, inclusive and effective way. Indeed, keeping food safe is one of the most basic applications of technology in the home.
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  • 15
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 173-179 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article outlines the importance of increasing fruit and vegetable intake in the battle against diet-related disease and health inequalities. It identifies some of the barriers to increasing fruit and vegetable consumption and proposes some potential solutions.
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  • 16
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 181-186 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Packed lunches are a popular form of midday meal for children at school. This study of 11-12-year-old children in Northern Ireland found sandwiches, crisps, chocolate and carbonated drinks to be popular items included in a packed lunch. Dairy produce and fruit were poorly represented. The nutritional quality varied with the type of lunch. The contribution of fat and saturated fatty acids to total energy intake were in all cases far in excess of recommended dietary guidelines. Such high intakes of fat militate against the reduction in the incidence of coronary heart disease in Northern Ireland. The intake of dietary fibre and several micronutrients were inadequate.Knowledge of healthier foods was not translated into food consumption. If major diseases in the longer term are to be minimised a challenge exists for those responsible for food preparation ± parents, food processors and suppliers in the hospitality industry to produce foods which are healthier while not adversely affecting their acceptability to children.
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  • 17
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 224-230 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Discusses the role appearance plays in influencing consumer perception and subsequent acceptance of a food product. Texture and flavour have long since been known to exert an effect on consumer perception. However, the "first taste is almost always with the eye". This is especially the case where a food product is sold through its appearance, rather than through its packaging. In addition, appearance can have a halo effect which modifies subsequent flavour perception and food acceptability. The article also briefly discusses the many factors that affect the perception process and the significance of food product development in the food industry.
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  • 18
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    Bingley : Emerald
    Nutrition & food science 99 (1999), S. 243-248 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This paper highlights the effectiveness of TCS (the Teaching Company Scheme) in improving the performance and competitiveness of companies in the food-processing industry. The industry is swinging towards the more efficient production of safe, high-quality foods, a change propelled by UK and EC legislation and by market forces. Developing and implementing new process procedures and systems, exploring and developing novel ingredients, new products and market sectors are projects that require heavy investment of time, resources and personnel. However, many small and medium-sized food-processing companies lack the resources necessary to carry out such strategic projects. TCS is a highly successful government scheme that stimulates innovation and facilitates technology and knowledge transfer in most business and industry sectors, including the food industry, by supporting partnerships between companies and the UK's knowledge base (universities and research organisations and institutions). It also enables companies to recruit and train high-calibre graduates seeking careers in industry.
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  • 19
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    Nutrition & food science 99 (1999), S. 131-135 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article highlights current research at the Leatherhead Food Research Association which is relevant to shelf-life assessment of food products. One area is to improve the quality and safety of fish - both fresh and cold-smoked. Food MicroModel, a computer software package which aids in the prediction of the microbiological safety and spoilage potential of food products, is described. New methods capable of predicting the stability of oils and fats to oxidation, which can be a significant cause of reduced shelf-life in fat-containing foods, are described. Novel analytical instruments, known as electronic noses, have been shown to have potential, as has a total antioxidant activity test. Temperature control in factories is often a compromise between product safety and the need to maintain reasonable employee working conditions. This is no longer a problem with the development of glove box technology, which separates the two environments. The final study discussed in this article is the development of accelerated shelf-life tests for chocolate products.
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  • 20
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    Nutrition & food science 99 (1999), S. 170-174 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A quantitative method involving colony counting was undertaken to assess the antibiotic effects of garlic Allium sativum on possible food-borne bacteria. The investigation using garlic was targeted at higher education students planning an Independent Study or Dissertation into the antibacterial properties of food plants. The effect of concentrations of garlic varying from 0 per cent to 20 per cent in chicken stock, which had been inoculated with either E.coli B and S. albus, was investigated over three days. Bacterial numbers were reduced with increased garlic concentration and with the duration of incubation. Heating the garlic for 30 min at 100 C destroyed its anti-bacterial activity.
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  • 21
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    Nutrition & food science 99 (1999), S. 237-243 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The recent arrival of the UK multiples has had a significant effect on the Northern Ireland market, particularly in terms of product range and choice. Ethnic foods offer a potentially lucrative sector, as evidenced in Great Britain. However, retailers in Northern Ireland are only beginning to develop range and ethnicity and are familiarising themselves with a market which has been characterised more often by traditional eating habits. The preliminary study considered consumer perceptions of ethnic food products in Northern Ireland. It would appear that product awareness needs to be developed carefully, and the onus is on the retailer (and indeed, the hospitality establishments) to inform consumers and respond to their needs and wants, particularly with the more recent trend towards regional cuisine and greater authenticity. Only then can a larger range of truly ethnic food products penetrate the Northern Ireland market successfully.
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  • 22
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    Nutrition & food science 99 (1999), S. 278-280 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: FOOD MATTERS is an award scheme that aims to encourage healthy eating amongst pupils in Hertfordshire schools. The FOOD MATTERS Award seeks to encourage a whole school approach to healthy eating. To achieve the Award, schools must carry out the following: set up a FOOD MATTERS co-ordination group; gain the FOOD MATTERS catering certificate by meeting set catering criteria; and identify and achieve targets regarding the promotion of healthy eating in school. Schools participating in FOOD MATTERS have carried out many different projects. These include a pupil-run healthier tuck shop; a "try it and you might like it" day (to encourage primary school pupils to eat more fruit and vegetables); the introduction of "fruit smoothies", (to increase pupils' intake of fruit and high-calcium foods); a fruit-sharing scheme; and the installation of new drinking fountains.
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  • 23
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    Nutrition & food science 99 (1999), S. 288-294 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article focuses on the consumption of fish in Qatar and its health benefits for those living in the region. The nutritional value of fish from traditional fishing areas such as the UK has been much discussed but this article addresses the value of fish from warmer regions. Samples of popular fish were purchased from the local market in Qatar and were then analysed for levels of major nutrients and fatty acids. The likely nutritional impact of fish on the local diet was then evaluated. Problems of preservation of fresh fish, hygiene and mercury levels are also pointed out. Vigilance on behalf of the Public Health Authorities is urged to ensure the good reputation of fish in this region remains.
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  • 24
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    Nutrition & food science 99 (1999), S. 295-302 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The objectives of the study are the standardization of ten Nigerian dishes and the determination of their proximate composition. Recipes for the ten dishes were obtained through the use of questionnaires. There were 200 respondents to the questionnaires consisting of housewives living in the major towns of south-western Nigeria. One recipe for each meal was extracted from a known cookery book. The means for each ingredient of all the dishes were calculated from ten randomly selected recipes and then used in the preparation of the standardized dishes. The standardized dishes are: Burabisko, Jollof rice, Agbono soup, Stewed beans and fried plantain, Bean pudding, Melon seed and vegetable soup, Ikokore, Eba imoyo, Yam and eggs and Yam pottage. Consumer acceptability tests were conducted as well as proximate analyses according to AOAC. All dishes were considered acceptable since they scored more than 3, the benchmark for acceptability. Energy content of the dishes ranged from 281Kcal/100g (Jollof rice) to 510Kcal/100g (Agbono soup). The crude protein content ranged from 7.5g/100g for Burabisko to 27.4g/100g for Jollof rice. The results suggest that these dishes are good sources of energy and protein.
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  • 25
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    Nutrition & food science 99 (1999), S. 5-11 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article briefly outlines the main objectives of the Ministry of Agriculture, Fisheries and Food (MAFF) programme of research in support of dietary surveys. It summarises the current portfolio of projects, then discusses in more depth the six projects being undertaken on further analysis of data from government dietary surveys, drawing on papers presented by the researchers at the annual meeting of this programme in London on 2 June 1998.
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  • 26
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    Nutrition & food science 99 (1999), S. 19-23 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Investigates the effects of ingredients and processing procedure on colour and appearance properties of chilled dairy dessert products, namely mousse. Chilled mousse products were formulated via a factorial design involving several ingredients and processing factors. Sixteen formulated dairy dessert mousses were presented to a trained sensory panel. A screening experiment was carried via a fractional factorial design involving eight factors at two levels. The effects were examined by means of graphical half normal plots using the software Design Ease (Stat-Ease Inc., USA). Five factors were identified as being the more significant factors which were cream level (CRE), mix time (MIX), blue (BLU), yellow (YEL) and red (RED) colouring agent levels. A further full factorial formulation design was carried out involving four factors: CRE, MIX, BLU, RYR (ratio of red to yellow additive) in a series of sensory perception experiments. Results verified by multivariate analysis of variance (MANOVA) indicated that it was the level of cream and colouring agents that were the most significant factors (p〈0.001) affecting colour and appearance aspects of chilled mousse.
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  • 27
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    Nutrition & food science 99 (1999), S. 29-36 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Manufacturers are producing an extensive range of added value products which are formulated using meat replacers but which are designed to appeal to a wide range of consumers, above and beyond the "traditional vegetarian" market. This study considered the relatively recent impact of such products on the Northern Ireland market, with a particular emphasis on the quality and acceptability of Quorn based products. A small- scale questionnaire (n = 100) considered customer perceptions of meat replacers, whilst the acceptance of selected tofu, textured vegetable protein (TVP) and Quorn products was measured using selected sensory evaluation techniques. The study concluded that Quorn can offer similar texture and flavour attributes to those consumers who wish to avoid meat products for health and/or safety reasons. It is this customer base which needs to be targeted, but it must be noted that negative perceptions of meat replacers still exist. Therefore, further developments need to be supported by appropriate marketing strategies which will both attract and educate consumers and help to achieve a sustained level of purchasing.
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  • 28
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    Nutrition & food science 99 (1999), S. 72-77 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The food and nutrient intake of 250 (135 male, 115 female) adolescent Nigerian high school students have been surveyed to determine the contributions of different food groups to their intakes of protein, calcium and iron. Twenty-four-hour dietary recall technique was used to obtain details of food intake and questionnaires administered to obtain social and economic circumstances of subjects' family. Male subjects had more energy, protein, calcium and iron intake but no significant (p 〈 0.05) differences when compared with females. Cereal based foods were the most important sources of dietary protein, supplying between 40-52 per cent for all subjects and 60 per cent or more for 29 per cent of the subjects. Proportions of dietary protein from legumes, meats, vegetables and roots ranged from10-21 per cent, 3-13 per cent, 7-17 per cent, 6.5-12.9 per cent respectively. Cereals were also the most important source of dietary calcium (56.8 per cent) and iron (33.16 per cent) for most subjects. The contribution of meats and legumes however, approximate that of cereals for 36 per cent of subjects. Apart from gender, residence at home or in boarding house and the socio-economic status of the subject's family significantly affect the sources of dietary protein, calcium and iron.
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  • 29
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    Nutrition & food science 99 (1999), S. 105-107 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The increasingly multidisciplinary nature of food in society has been reflected at South Bank University by the development of undergraduate courses in Food Science and Technology; Food, Nutrition and Health; and Food Choice and Design. The ethos of The Food Programme of courses is outlined and the structure explained. Applications from students from a wide variety of backgrounds are welcome - provided they have a real interest in food.
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    Nutrition & food science 99 (1999), S. 136-139 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This paper discusses the findings of a market research programme carried out by SMRC ChildWise on behalf of Tetra Pak UK Ltd, examining use of and attitudes to soft drinks among children and mothers. This is a product field of increasing interest to children as they grow, and their appreciation develops from being totally product-focused, to include packaging and then brand considerations. The research examined behaviour across the key drinking occasions that make up the child's day, looking in detail at drinks consumed at school. It is at school that a child's freedom of choice develops, and awareness of peer group influences becomes increasingly important. Children are highly receptive to new brands and flavours, but also demand professional packaging and promotional input for brands to be credible. Younger children appreciate having their own individual carton with a straw but, for older boys, a can is preferred, whilst girls like the practicalities of resealable bottles.
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    Nutrition & food science 99 (1999), S. 81-88 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Describes chromium's importance in nutrition and health, pinpointing its sources in diets and facts about its absorption in humans. Outlines the body's ability to store chromium and the function of the element. Reports on current recommendations of safe and adequate levels of intake. The symptoms of chromium deficiency are discussed as are the toxic effects of too high an intake. Concludes with recommendations for required further research.
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  • 32
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    Nutrition & food science 99 (1999), S. 89-98 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: While there is considerable anecdotal evidence and some research indicating poor nutritional intake and high levels of food wastage in hospitals, there have been no studies relating these issues to the catering system used. The overall purpose of this study was, therefore, to measure food wastage and nutritional intake in selected hospital catering systems. Data were collected from three types of ward (elderly, medical and surgical) in four hospitals (nine wards), two in London and two in Southern England. Three wards used food cooked mainly in the hospital kitchen, six used cook-chill and cook-freeze dishes bought in ready prepared. Five of the wards used a bulk system where food is transported to the ward and plated, in the others, food is plated in the hospital kitchen then transported to the ward. Food sent to the ward, served to patients, and that which remained uneaten or left on the service trolley was weighed for a minimum of 24 hours in each ward; 966 patient-meal-days. This data enabled food wastage and nutritional intake to be calculated. Results indicate that food wastage was lower at the breakfast meal, than the midday and evening meal, 23.10 per cent, 39.99 per cent and 42.35 per cent, respectively; female wastage was higher than male, 33.91 per cent and 27.26 per cent, respectively; wastage was higher where food was plated in wards rather than in the kitchen, 57.75 per cent and 35.28 per cent, respectively; and wastage was higher where food was purchased-in ready prepared, rather than prime cooked in the hospital kitchen. Nutritional intake was calculated for five wards and in all, energy intake was below the recommendations, the highest deficit being 58 per cent. Deficiencies were also noted for other nutrients.
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  • 33
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    Nutrition & food science 99 (1999), S. 99-104 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Zinc and essential fatty acid deficiencies manifest similar syndromes provoking investigations into the mechanisms underlying their metabolic interactions. This article presents a lucid and concise review of literature on the possible connection between these important dietary nutrients as exemplified by the role of zinc in modulating intestinal lipid transport and prostaglandins metabolisms as well as maintenance of membrane structural and functional integrity. Reports of investigations on zinc and essential fatty acid deficiencies, regarding their pleitropic effects on clinically important enzymes, from the laboratory of the authors were also considered.
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  • 34
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    Nutrition & food science 99 (1999), S. 285-287 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Describes coeliac disease with its increased risk of osteoporosis for the patient. Often misdiagnosed or not recognised early, coeliac disease leads to further complications, particularly osteoporosis. Provides eating/nutrition guidelines for coeliac sufferers to avoid osteoporosis in later life.
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    Nutrition & food science 99 (1999), S. 303-306 
    ISSN: 0034-6659
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Highlights the prevalence, causes and health risks of obesity. Then continues by looking at the health incentives of weight loss through commercial weight-reducing diets and the health problems incurred during such a diet in respect of reduced energy intake and reduction of non-starch polysaccharides which can lead to constipation and associated bowel diseases. Tips to increase the intake of non-starch polysaccharides are given in the context of weight-reduction programmes.
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  • 36
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    Pigment & resin technology 28 (1999), S. 279-282 
    ISSN: 0369-9420
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A lamellar zinc pigment reacts in aqueous alkaline media (e.g. water-borne paints) with the evolution of hydrogen. This corrosion reaction can be inhibited by certain surfactants. The most important structural part of the examined surfactants is the hydrophilic group; only anionic phosphate or phosphonate hydrophilic groups are effective corrosion inhibitors. Surfactants with carboxylate, sulfonate, amphoteric, cationic and non-ionic hydrophilic groups are ineffective. There seems to be also an influence of the hydrophobic group of the surfactants because a partial ester of phosphoric acid with a fluorinated hydrophobic group was the most effective corrosion inhibitor in this study.
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  • 37
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    Pigment & resin technology 28 (1999), S. 283-292 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Reports the effects of composition and curing temperature on the film properties of three water reducible enamels prepared from palm stearin alkyds. The properties studied were hardness, flexibility, and adhesion. While all the formulations exhibit excellent adhesion, generally increasing the melamine content and curing temperature can increase the hardness but reduce the resistance to cracking and deformation of the coating. Applies Fourier transform infra-red spectroscopy (FTIR) to the study of the curing reactions. Finds that FTIR is able to identify the predominant cross-linking reactions.
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  • 38
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    Pigment & resin technology 28 (1999), S. 326-330 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Fillers with different chemical properties were used to study their effects on poly(vinyl acetate) (PVAc) emulsion wood adhesives. The elastoplastic behaviour of the filler treated PVAc emulsions was studied using differential scanning calorimetry and dynamic mechanical thermal analysis. The results show that the glass transition temperature (Tg) of the polymer is not changed significantly by the addition of the fillers, while the tensile modulus is changed together with the hardness and stiffness. The viscosity of the emulsions and their performance on wood surfaces are greatly affected by fillers. Fillers with high oil-absorption capacity increase viscosity to a greater extent. The acidity of the fillers influences the setting time for bonding of the emulsions to wood, and the water resistance, since some chemical reactions can take place during curing.
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  • 39
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    Pigment & resin technology 28 (1999), S. 336-341 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Copolymer resins of peanut skin tannin extract, aldehydes and cashew nut shell liquid were prepared. The resins were blended with bitumen and used in formulating oleoresinous wood varnishes. The film properties of the varnishes were determined and the results showed that the gloss and scratch hardness of the films increased with increase in the quantity of cashew nut shell liquid/tannin-aldehyde resins incorporated. The results also showed that the resins improved the chemical resistance of the varnish films. Varnish compositions containing 50:50 of bitumen and the resins gave films with satisfactory physical and chemical properties. The study showed that it is possible to formulate excellent oleoresinous wood varnishes using blends of bitumen and cashew nut shell liquid/tannin-aldehyde resins.
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    Pigment & resin technology 28 (1999), S. 341-344 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Benzamide has been made to undergo Hofmann rearrangement, in the presence of hypochlorite (OCl-) generated in situ, by the electrolysis of sodium chloride solution using platinised titanium anode and graphite cathode. The product is not a pure primary amine, namely aniline; but a polymeric aniline derivative is produced. It has a free amino end; and/or a free amino end is generated during the process of diazotisation. The product has been diazotised and coupled with naphthols to give dyes. The nature of the dyes have been analysed by uv-visible spectral studies. The dyes are slightly different from the dyes prepared from pure aniline.
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  • 41
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Surface of precipitated silica was modified with 3-aminopropyltriethoxysilane. The optimum solvent was selected, in which the silane coupling agent was deposited on silica surface. Basic physicochemical properties of the modified silica were estimated. Methods of evaluating silica surface modification extent were presented, taking advantage first of all of its altered hydrophilicity and of differences in condensation extent of surface silanol groups. The modified silica was used as adsorbent capable of trapping water soluble organic amines.
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  • 42
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    Pigment & resin technology 28 (1999), S. 293-296 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Peanut skin tannin extract-formaldehyde condensates were modified with resorcinol and cashew nut shell liquid. The copolymer resins formed were used as thermosetting and cold-setting exterior grade wood adhesives for Sapele veneer panels. Results obtained showed that, on addition of paraformaldehyde, the resins modified with resorcinol cured at ambient temperatures while those modified with cashew nut shell liquid cured at higher temperatures. The bonded panels developed strength and durability satisfying the requirements of International Standard Specification for phenolic resin adhesives.
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    Pigment & resin technology 28 (1999), S. 331-336 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Traditionally aerospace coatings have been formulated for performance. In an extreme case a faulty coating could contribute to an accident on a catastrophic scale. The demands on aerospace coatings are severe because aircraft have unusual requirements. These requirements are dictated by the environment in which modern aircraft operate, the nature of the structure of the airframe, the way they are painted and the way in which they are used. As a consequence of all this, the paints which have been formulated for aerospace use usually differ from paint used in other industrial areas. It has often meant using ingredients which are regarded as hazardous either to health, such as chromate pigments, or to the environment, such as large quantities of strong solvents. Bearing this in mind, modern formulations have had to evolve, improving performance and taking into account the results of using hazardous ingredients which might affect users of the coatings, innocent bystanders and the environment. Here we consider the conflict between these influences and show the position reached within the industry.
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  • 44
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    Pigment & resin technology 28 (1999), S. 83-88 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Aims to prepare some organotin polymers based on N-substituted acrylamide and methylacrylamide acid esters via a new synthetic route. Tri-n-butyltin-?-bromoacrylate monomer (TBTBA) was prepared and polymerisation carried out. Organotin polymers were prepared via the new synthetic route by exchange reactions.
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  • 45
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    Pigment & resin technology 28 (1999), S. 158-161 
    ISSN: 0369-9420
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article describes the move towards integrated coating systems, where the coating and method of drying or curing are selected to ensure efficient coating processes, while ensuring there is no reduction in the function of the coating itself. It briefly explores various methods of radiation curing and explains how these techniques can be used to meet production requirements and constraints and develop optimum coating solutions. There is also a brief case study, which describes the installation of an infra-red system for pre-heating steel drums in order to speed up a lacquering operation.
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    Pigment & resin technology 28 (1999), S. 143-148 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Lignin precipitated from different black liquors wasted from the cooking of rice straw, bagasse and cotton stalks, to produce pulp and paper, can replace phenol by up to 40 per cent in phenol formaldehyde resin. The properties of the resin produced from bagasse lignin formaldehyde are nearly the same as when the resin IS produced from phenol formaldehyde. Replacement of phenol by lignin in phenol formaldehyde resin has an economical effect and reduces the pollution caused by draining black liquor into rivers and streams. The properties of the resin produced from rice straw lignin are lower than resin from bagasse and cotton stalk lignin. The effect of increasing the content of lignin in the resin on the resin properties was studied. The effect of polymerization time and temperature on the resin properties is also clarified. The molecular structure of the lignins used plays an important role on the properties of the phenol lignin formaldehyde produced.
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  • 47
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    Pigment & resin technology 28 (1999), S. 233-237 
    ISSN: 0369-9420
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article describes the background to the widespread application of infrared radiation as a curing technique for paints and coatings, from its origins in the 1930s to the present day. It explains the mechanism of infrared and elaborates on some of the developments which have been made in the technology, especially in terms of control and response. The benefits of infra-red drying and curing are further illustrated by reference to case studies demonstrating infrared in action.
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    Pigment & resin technology 28 (1999), S. 230-232 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Aqueous sodium chloride solution, containing benzamide was electrolysed (pH = 2), using platinised titanium anode and graphite cathode. The filtrate of the reaction mixture (pH = 4.5) was diazotised and coupled with a-naphthol in NaOH and also with ß-naphthol in NaOH. Dyes were produced. These dyes were matched with the standard dyes prepared from aniline. Uv-visible absorption spectral study reveals that the dyes produced are slightly different from the standard dyes. During the course of the reaction benzamide is converted into aniline with a long chain polymeric unit having a free amino end; and/or a polymeric unit which generates a free amino end during the process of diazotisation.
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  • 49
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    Pigment & resin technology 28 (1999), S. 217-222 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: In many markets customers judge the quality of products by their surface appearance. The term gloss describes the perception of the shiny appearance of a surface when light is reflected from that surface. Imperfections in a surface cause some of the light to be reflected/scattered at angles away from the specular and this impacts on the visual assessment of appearance. A method has existed for measuring surface reflectance for the last 50 years, but its usefulness has been limited by an inability to equal the human eye in discerning subtleties such as haze or distinctness of reflected images. A portable instrument has now been developed to take measurements about the specular, spaced at less than three minutes of arc. This paper explains how this high resolution supports the introduction of additional indices to define haze, distinctness of image and peak specular reflectance while retaining the definition of "gloss" as described in the standard method ISO2813.
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    Pigment & resin technology 28 (1999), S. 6-14 
    ISSN: 0369-9420
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Colour preferences have both scientific significance and relevance to manufacturers. Despite claims that these preferences are unsystematic and that saturation and brightness exert more influence on judgements than hue, a substantial body of research suggests that the rank order of preference for hues - blue, red, green, violet, orange, yellow - emerges with some degree of consistency and, in particular, blue is regularly preferred to other hues. Five explanations of this trend are considered: preferences are simply conventional; blue is more neutral and less susceptible to extremes of judgement than other hues; preference for blue is a by-product of more general principles; blue has largely positive associations; blue has an evolutionary significance. It is proposed that further investigation of the connotations of hues will provide insight into the pattern of colour preferences.
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    Pigment & resin technology 28 (1999), S. 26-30 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: UV-curable systems based on the copolymerisation of a typical acrylic resin with low amount of fluorinated monomers (less than 1 per cent w/w) were prepared. The bulk properties of the films were unchanged, while a strong modification of the surface was obtained, depending on the monomer structure, on its concentration and on the type of substrate.
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    Pigment & resin technology 28 (1999), S. 31-33 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Briefly discusses the search for alternatives to CFCs in aerosols for precision cleaning applications. Gives properties of several solvents used in cleaning applications. Considers five key parameters for selecting a solvent for aerosol applications.
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    Pigment & resin technology 28 (1999), S. 75-82 
    ISSN: 0369-9420
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Discusses the use of piperylene-styrene copolymer (PSC) for polychloroprene adhesive modification. States that PSC significantly improves modified adhesive properties - bond strength, viscosity, high heat resistance, good adhesion to a variety of substrates, compatibility with other adhesive additives. Looks at the advantage of using more environmentally friendly technology for thermoplastic rubber bonding with PSC modified polychloroprene adhesives. Concludes that the new adhesive product can be used for specific combinations of materials and application methods, making it possible to produce cheaper and better products.
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    Pigment & resin technology 28 (1999), S. 212-216 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: New acrylic and allylic resins were prepared by functionalising perfluoropolyethers chains, which assured peculiar surface properties. Blends having a different amount of the acrylic and of the allylic systems were cured in air by UV irradiation. The cure of the films was found dependent on the ratio between the two resins; the concentration for the obtaining of a film fully cured in air was determined. On the basis of this concentration, a macromer functionalised with the right amount of both the acrylic group and the allylic one was synthesised.
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    Pigment & resin technology 28 (1999), S. 15-25 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Environmental, economic and market pressures have led to a dramatic increase in the production of recycled paper fibre in recent years and the growing demand for higher quality grades is now focusing attention on the recycling of office wastes. Although the role of chemistry in the recycling process for paper is well established, the introduction of newer inks and adhesives into the recycling chain has added to the existing problems of "getting the chemistry right". This article examines the impact on the deinking of secondary paper fibre resulting from evolving ink technologies, catalysed by developments in the printing processes.
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    Pigment & resin technology 28 (1999), S. 70-74 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Hydroxy terminated polyesters were prepared by the reaction of tetrabromophthalic, phthalic, and maleic anhydrides with polyethylene glycol via melt condensation technique. They were characterized by hydroxy number, and intrinsic viscosity measurements. Also, the fire retardancy of polyesters was evaluated as varnish films on plywood strips. The polyesters were reacted with excess toluene -2, 4- diisocyanate to yeild isocyanate terminated prepolymers which were subsequently reacted with 5, 5- dihydroxymethyl-2-trichloro-methyl-1,3- dioxane or ethelene diamine. These polymers were characterized by Ir and 1H NMR spectra, viscosity measurements, and thermogravimetric analysis.
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    Pigment & resin technology 28 (1999), S. 223-229 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article provides a summary of the Health and Safety Executive's (HSE) work over recent years to address occupational exposure to particulates during the manufacture and use of coating powders. It contends, in particular, that many users of coating powders are not controlling exposure to total inhalable particulate (TIP) (i.e. the total inhalable dust in the air from all sources), and that these control issues would exist even if TGIC (triglycidyl isocyanurate) was not being used. TGIC is a curing agent for polyester coating powders which is classified as a Category 2 mutagen. HSE is raising awareness that control of exposure is generally poor whatever powders are being used.
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    Pigment & resin technology 28 (1999), S. 149-157 
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    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Titanium dioxide pigments have been produced commercially for eight decades. The industry has seen many developments from the humble beginnings with uncoated, impure, anatase pigments to the highly refined TiO2 pigments of today. For the past four decades there have been two commercial routes for making TiO2 pigments - sulphate and chloride. In recent years, significant efforts have been made to produce TiO2 by both routes with greater environmental awareness. To compare the overall impact of TiO2 manufacturing processes on the environment, life-cycle assessments of several process options are described in this paper.
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Normile, D -- New York, N.Y. -- Science. 1998 Dec 11;282(5396):1975-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874644" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Husbandry/*methods ; Animals ; Blastocyst ; Cattle/embryology/*genetics ; Cell Differentiation ; Cells, Cultured ; *Cloning, Organism ; Embryo Transfer/veterinary ; Fallopian Tubes/cytology ; Female ; Japan ; *Nuclear Transfer Techniques ; Oocytes ; Ovarian Follicle/cytology ; Pregnancy
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goldman, L R -- New York, N.Y. -- Science. 1998 Dec 4;282(5395):1825-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874633" target="_blank"〉PubMed〈/a〉
    Keywords: Child ; Environmental Exposure ; Environmental Pollutants/adverse effects ; Government Agencies ; Humans ; Lead/adverse effects ; Lead Poisoning/*prevention & control ; United States ; United States Environmental Protection Agency
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Spear, P G -- New York, N.Y. -- Science. 1998 Dec 11;282(5396):1999-2000.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Northwestern University Medical School, Department of Microbiology-Immunology, Chicago, IL 60611, USA. p-spear@nwu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874652" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bacterial Adhesion ; Cytoskeletal Proteins/genetics/*metabolism ; Dystroglycans ; Humans ; Laminin/metabolism ; Lassa Fever/*virology ; Lassa virus/*metabolism ; Leprosy/*microbiology ; Lymphocytic choriomeningitis virus/metabolism ; Membrane Glycoproteins/genetics/*metabolism ; Models, Biological ; Mycobacterium leprae/*metabolism ; Receptors, Virus/metabolism ; Schwann Cells/microbiology
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gough, M -- New York, N.Y. -- Science. 1998 Dec 4;282(5395):1823.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874631" target="_blank"〉PubMed〈/a〉
    Keywords: 2,4,5-Trichlorophenoxyacetic Acid/adverse effects ; 2,4-Dichlorophenoxyacetic Acid/adverse effects ; Confidentiality/*legislation & jurisprudence ; Defoliants, Chemical ; Financing, Government ; Humans ; *Public Policy ; Research/*legislation & jurisprudence ; *Research Support as Topic ; Tetrachlorodibenzodioxin/adverse effects ; United States
    Print ISSN: 0036-8075
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abramson, P R -- Pinkerton, S D -- New York, N.Y. -- Science. 1998 Dec 11;282(5396):1993-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874650" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anura/*genetics/physiology ; *Biological Evolution ; Male ; Selection, Genetic ; *Sexual Behavior, Animal ; *Vocalization, Animal
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Adams, M W -- Stiefel, E I -- New York, N.Y. -- Science. 1998 Dec 4;282(5395):1842-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA. adams@bmb.uga.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874636" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; Carbon Monoxide/chemistry ; Clostridium/*enzymology ; Crystallography, X-Ray ; Cyanides/chemistry ; Humans ; Hydrogen/*metabolism ; Hydrogenase/*chemistry/*metabolism ; Iron/chemistry ; Ligands ; Oxidation-Reduction ; Pyruvic Acid/metabolism
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Penney, B K -- New York, N.Y. -- Science. 1998 Dec 11;282(5396):1992-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874647" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Evolution ; Drosophila/*genetics/physiology ; *Drosophila Proteins ; GTP-Binding Proteins/*genetics ; Genes, Helminth ; Genes, Insect ; Longevity ; Nematoda/*genetics/physiology ; Receptors, Cell Surface/*genetics ; *Receptors, G-Protein-Coupled ; Selection, Genetic
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pennisi, E -- New York, N.Y. -- Science. 1998 Dec 11;282(5396):1972-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874643" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Caenorhabditis elegans/cytology/*genetics/physiology ; Cell Lineage ; Chromosome Mapping ; DNA, Helminth/chemistry/genetics ; Evolution, Molecular ; Gene Expression Regulation ; *Genes, Helminth ; Genetic Techniques ; *Genome ; Humans ; Mutation ; *Sequence Analysis, DNA
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pennisi, E -- New York, N.Y. -- Science. 1998 Dec 4;282(5395):1796.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874626" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Crosses, Genetic ; Drosophila/*genetics ; Female ; *Genes, Insect ; HSP90 Heat-Shock Proteins/genetics/*physiology ; Insect Proteins/genetics/physiology ; Male ; *Mutation ; Temperature
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sussman, J L -- New York, N.Y. -- Science. 1998 Dec 11;282(5396):1993.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9874649" target="_blank"〉PubMed〈/a〉
    Keywords: *Databases, Factual ; Periodicals as Topic ; Proteins/*chemistry ; Publishing
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-09-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hagmann, M -- New York, N.Y. -- Science. 1999 Aug 20;285(5431):1200-1, 1203.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10484727" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylation ; Acetyltransferases/chemistry/metabolism ; Animals ; Cell Cycle Proteins/chemistry/metabolism ; Chromatin/chemistry/*metabolism/*ultrastructure ; *Gene Expression Regulation ; Histone Acetyltransferases ; Histones/*metabolism ; Methylation ; *Mitosis ; Phosphorylation ; Protein Structure, Secondary ; Protein-Arginine N-Methyltransferases/metabolism ; Transcription Factors ; p300-CBP Transcription Factors
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-07-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, R F -- New York, N.Y. -- Science. 1999 Jul 9;285(5425):186.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10428712" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Products/chemistry/isolation & purification ; *Chemistry, Pharmaceutical ; Drug Design ; *Drug Industry ; *Pharmaceutical Preparations/chemical synthesis/chemistry ; Technology, Pharmaceutical
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-09-08
    Description: Postdoctoral appointments can have different functions and meanings, depending on the field and whether the postdoc is a man or a woman. The Ph.D.'s-Ten Years Later study confirmed that in biochemistry, the postdoc, not the Ph.D., has become the general proving ground for excellence both in academia and industry. Because they spent a longer time in these "mandatory" postdocs, biochemists had the largest proportion of untenured faculty 10 to 13 years after the Ph. D. In mathematics, where substantially fewer postdoctoral positions are available, Ph.D.'s taking postdocs are more likely to obtain faculty positions, but this is true only for men. University administrators should be accountable for monitoring the total time spent in these positions and should provide administrative assistance for skills training, career growth, and the job search. In addition, creative solutions concerning the dual-career couple phenomenon are necessary.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nerad, M -- Cerny, J -- New York, N.Y. -- Science. 1999 Sep 3;285(5433):1533-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Graduate Division, University of California, Berkeley, 424 Sproul Hall, Berkeley, CA 94720-5900, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10477510" target="_blank"〉PubMed〈/a〉
    Keywords: *Biochemistry/education ; *Career Mobility ; *Education, Graduate ; Employment ; Faculty ; *Fellowships and Scholarships ; Female ; Humans ; Male ; *Mathematics ; Salaries and Fringe Benefits ; Societies, Scientific ; Time Factors ; United States ; Universities
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-10-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Westhof, E -- New York, N.Y. -- Science. 1999 Oct 1;286(5437):61-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institut de Biologie Moleculaire et Cellulaire du CNRS, Strasbourg, France. westhof@ibmc.u-strasbg.fr〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10532891" target="_blank"〉PubMed〈/a〉
    Keywords: Base Pairing ; Catalysis ; Cytosine/chemistry/metabolism ; Hepatitis Delta Virus/*enzymology ; Hydrogen-Ion Concentration ; Imidazoles/chemistry/metabolism/pharmacology ; Mutagenesis ; Point Mutation ; RNA, Catalytic/*chemistry/*metabolism
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Couzin, J -- New York, N.Y. -- Science. 1998 Dec 18;282(5397):2175-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9890822" target="_blank"〉PubMed〈/a〉
    Keywords: Budgets ; Cartilage ; *Complementary Therapies/economics/organization & administration ; Controlled Clinical Trials as Topic ; Humans ; Lung Neoplasms/therapy ; National Institutes of Health (U.S.)/economics/*organization & administration ; Research Support as Topic ; Tissue Extracts/therapeutic use ; United States
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-04-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nitta, I -- Kamada, Y -- Noda, H -- Ueda, T -- Watanabe, K -- New York, N.Y. -- Science. 1999 Mar 26;283(5410):2019-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10206907" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-09-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wickelgren, I -- New York, N.Y. -- Science. 1999 Aug 13;285(5430):999.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10475850" target="_blank"〉PubMed〈/a〉
    Keywords: Biotechnology/history ; Genetics, Medical/history ; Genome, Human ; History, 20th Century ; Humans ; United States
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-06-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, R F -- New York, N.Y. -- Science. 1999 Jun 4;284(5420):1598-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10383329" target="_blank"〉PubMed〈/a〉
    Keywords: Chemistry, Pharmaceutical ; Enzyme Inhibitors/*chemical synthesis/chemistry ; Maleic Anhydrides/*chemical synthesis/chemistry
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    Publication Date: 1999-04-09
    Description: A functioning logic gate based on quantum-dot cellular automata is presented, where digital data are encoded in the positions of only two electrons. The logic gate consists of a cell, composed of four dots connected in a ring by tunnel junctions, and two single-dot electrometers. The device is operated by applying inputs to the gates of the cell. The logic AND and OR operations are verified using the electrometer outputs. Theoretical simulations of the logic gate output characteristics are in excellent agreement with experiment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Amlani I -- Orlov -- Toth -- Bernstein -- Lent -- Snider -- New York, N.Y. -- Science. 1999 Apr 9;284(5412):289-91.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA. Neuromorphic Information Technology Graduate Center, Budapest, Kende-u.13, H-1111, Hungary.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10195887" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-07-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, R F -- New York, N.Y. -- Science. 1999 Jul 9;285(5425):184-5, 187.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10428711" target="_blank"〉PubMed〈/a〉
    Keywords: Biological Products/chemical synthesis/chemistry ; *Chemistry, Organic ; *Chemistry, Pharmaceutical ; Drug Design ; Drug Industry ; Organic Chemicals/*chemical synthesis/chemistry ; Organic Chemistry Phenomena ; Pharmaceutical Preparations/*chemical synthesis/chemistry
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-12-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Collignon, P -- New York, N.Y. -- Science. 1999 Dec 3;286(5446):1855-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10610574" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies, Viral/analysis ; *Gammaretrovirus/immunology ; Humans ; Retroviridae Infections/diagnosis/*transmission ; *Swine/virology ; *Transplantation, Heterologous/adverse effects
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, R F -- New York, N.Y. -- Science. 1999 Apr 23;284(5414):578-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10328734" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Electric Stimulation ; Electrodes ; Electrodes, Implanted ; *Electronics ; Electrophysiology ; Humans ; Nerve Net/*physiology ; Nervous System Diseases/*therapy ; Neurons/*physiology ; Rats ; Silicon ; *Transistors, Electronic
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  • 81
    Publication Date: 1999-01-15
    Description: Mutator genotypes with increased mutation rates may be especially important in microbial evolution if genetic adaptation is generally limited by the supply of mutations. In experimental populations of the bacterium Escherichia coli, the rate of evolutionary adaptation was proportional to the mutation supply rate only in particular circumstances of small or initially well-adapted populations. These experiments also demonstrate a "speed limit" on adaptive evolution in asexual populations, one that is independent of the mutation supply rate.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arjan, J A -- Visser, M -- Zeyl, C W -- Gerrish, P J -- Blanchard, J L -- Lenski, R E -- New York, N.Y. -- Science. 1999 Jan 15;283(5400):404-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824, USA. arjan.devisser@algemeen.micr.wau.nl〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9888858" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptation, Physiological ; *Biological Evolution ; Escherichia coli/*genetics/physiology ; Genetics, Population ; Genotype ; Linear Models ; *Models, Biological ; *Mutation
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-04-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, R F -- New York, N.Y. -- Science. 1999 Mar 12;283(5408):1668-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10189320" target="_blank"〉PubMed〈/a〉
    Keywords: Biomechanical Phenomena ; Cell Nucleus/metabolism ; Chromatin/physiology ; DNA/*chemistry/genetics/*metabolism ; DNA Replication ; DNA Topoisomerases, Type I/metabolism ; DNA-Directed RNA Polymerases/chemistry/metabolism ; Exodeoxyribonucleases/metabolism ; Gene Expression ; Lasers ; Molecular Motor Proteins ; Nucleic Acid Conformation ; Sequence Analysis, DNA ; Viral Proteins
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-12-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Langan, P -- Schoenborn, B P -- New York, N.Y. -- Science. 1999 Nov 5;286(5442):1089.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10610521" target="_blank"〉PubMed〈/a〉
    Keywords: Crystallography/*instrumentation ; *Neutrons ; Proteins/*chemistry ; United States
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nilsson, A -- Rose, J -- New York, N.Y. -- Science. 1999 Oct 29;286(5441):894.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10577238" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Specimen Banks/legislation & jurisprudence ; Biotechnology ; Ethics Committees ; *Ethics, Research ; *Genetic Privacy ; *Genetic Research ; Government Regulation ; Humans ; *Privacy/legislation & jurisprudence ; Public Policy ; Sweden
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-03-05
    Description: Seismic reflection profiles, petroleum wells, and relocated earthquakes reveal the presence of an active blind-thrust fault beneath metropolitan Los Angeles. A segment of this fault likely caused the 1987 Whittier Narrows (magnitude 6.0) earthquake. Mapped sizes of other fault segments suggest that the system is capable of much larger (magnitude 6.5 to 7) and more destructive earthquakes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shaw -- Shearer -- New York, N.Y. -- Science. 1999 Mar 5;283(5407):1516-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Earth and Planetary Sciences, Harvard University, Cambridge, MA 02138, USA. Institute of Geophysics and Planetary Physics, Scripps Institute of Oceanography, University of California, San Diego, La Jolla, CA 92093-0225, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10066170" target="_blank"〉PubMed〈/a〉
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  • 86
    Publication Date: 1999-11-05
    Description: The spatio-temporal evolution of a propagating magma-filled crack was estimated from inversion of Global Positioning System (GPS) data, tiltmeters, and leveling. The dike opened at a maximum rate of 50 millimeters per day and had a peak magma flux of 2 x 10(6) cubic meters per day. Although the spatial resolution was limited, slow upward propagation was resolved during the 9-day-long intrusion. In contrast, the earthquakes migrated rapidly upward during the first 12 hours of the swarm, and nearly all of the seismic energy was released in the first 2 days. Comparison of inversion results with accurate hypocenter locations will lead to improved understanding of magma transport through the brittle crust and of the causes of volcanic seismicity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aoki -- Segall -- Kato -- Cervelli -- Shimada -- New York, N.Y. -- Science. 1999 Oct 29;286(5441):927-30.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Geophysics, Stanford University, Stanford, CA 94305-2215, USA. Earthquake Research Institute, University of Tokyo, 1-1, Yayoi 1, Bunkyo-ku, Tokyo 113-0032, Japan. National Research Institute for Earth Science and Disaster Preve.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10542140" target="_blank"〉PubMed〈/a〉
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  • 87
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-07-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Appenzeller, T -- New York, N.Y. -- Science. 1999 Jun 25;284(5423):2108-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10409068" target="_blank"〉PubMed〈/a〉
    Keywords: *Adaptation, Physiological ; *Biological Evolution ; Culture Media ; *Ecosystem ; Escherichia coli/*genetics/physiology ; Glucose/metabolism ; Maltose/metabolism ; *Mutation ; Pseudomonas fluorescens/*genetics/physiology ; Selection, Genetic
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  • 88
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-04-09
    Description: A "switch" mutant of the Arc repressor homodimer was constructed by interchanging the sequence positions of a hydrophobic core residue, leucine 12, and an adjacent surface polar residue, asparagine 11, in each strand of an intersubunit beta sheet. The mutant protein adopts a fold in which each beta strand is replaced by a right-handed helix and side chains in this region undergo significant repacking. The observed structural changes allow the protein to maintain solvent exposure of polar side chains and optimal burial of hydrophobic side chains. These results suggest that new protein folds can evolve from existing folds without drastic or large-scale mutagenesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cordes, M H -- Walsh, N P -- McKnight, C J -- Sauer, R T -- AI-15706/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1999 Apr 9;284(5412):325-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10195898" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Amino Acid Substitution ; Asparagine/chemistry ; Circular Dichroism ; Hydrogen Bonding ; Leucine/chemistry ; Models, Molecular ; Molecular Sequence Data ; Mutagenesis, Insertional ; Nuclear Magnetic Resonance, Biomolecular ; Protein Conformation ; *Protein Folding ; *Protein Structure, Secondary ; Protein Structure, Tertiary ; Repressor Proteins/*chemistry ; Viral Proteins/*chemistry ; Viral Regulatory and Accessory Proteins
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 89
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-07-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Laver, W G -- New York, N.Y. -- Science. 1999 Jun 25;284(5423):2089.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10409063" target="_blank"〉PubMed〈/a〉
    Keywords: Crystallization ; Neuraminidase/*chemistry ; *Space Flight ; *Spacecraft ; United States ; United States National Aeronautics and Space Administration ; *Weightlessness
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  • 90
    Publication Date: 1999-10-09
    Description: The Yersinia pseudotuberculosis invasin protein promotes bacterial entry by binding to host cell integrins with higher affinity than natural substrates such as fibronectin. The 2.3 angstrom crystal structure of the invasin extracellular region reveals five domains that form a 180 angstrom rod with structural similarities to tandem fibronectin type III domains. The integrin-binding surfaces of invasin and fibronectin include similarly located key residues, but in the context of different folds and surface shapes. The structures of invasin and fibronectin provide an example of convergent evolution, in which invasin presents an optimized surface for integrin binding, in comparison with host substrates.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hamburger, Z A -- Brown, M S -- Isberg, R R -- Bjorkman, P J -- New York, N.Y. -- Science. 1999 Oct 8;286(5438):291-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biology 156-29, Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10514372" target="_blank"〉PubMed〈/a〉
    Keywords: *Adhesins, Bacterial ; Amino Acid Sequence ; Bacterial Proteins/*chemistry/metabolism ; Binding Sites ; Crystallography, X-Ray ; Evolution, Molecular ; Fibronectins/chemistry/metabolism ; Hydrogen Bonding ; Integrins/*metabolism ; Ligands ; Models, Molecular ; Protein Binding ; Protein Conformation ; Protein Folding ; Protein Structure, Secondary ; Yersinia pseudotuberculosis/*chemistry/metabolism
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  • 91
    Publication Date: 1999-09-25
    Description: The flow of information from calcium-mobilizing receptors to nuclear factor of activated T cells (NFAT)-dependent genes is critically dependent on interaction between the phosphatase calcineurin and the transcription factor NFAT. A high-affinity calcineurin-binding peptide was selected from combinatorial peptide libraries based on the calcineurin docking motif of NFAT. This peptide potently inhibited NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. Substitution of the optimized peptide sequence into the natural calcineurin docking site increased the calcineurin responsiveness of NFAT. Compounds that interfere selectively with the calcineurin-NFAT interaction without affecting calcineurin phosphatase activity may be useful as therapeutic agents that are less toxic than current drugs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aramburu, J -- Yaffe, M B -- Lopez-Rodriguez, C -- Cantley, L C -- Hogan, P G -- Rao, A -- R01 AI 40127/AI/NIAID NIH HHS/ -- R01 GM056203/GM/NIGMS NIH HHS/ -- R01 HL 03601/HL/NHLBI NIH HHS/ -- R43 AI 43726/AI/NIAID NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1999 Sep 24;285(5436):2129-33.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10497131" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Binding Sites ; Calcineurin/*metabolism ; Calcineurin Inhibitors ; Cell Nucleus/metabolism ; Cyclosporine/pharmacology ; Cytokines/biosynthesis/genetics ; DNA-Binding Proteins/*antagonists & inhibitors/chemistry/metabolism ; Gene Expression Regulation ; Genes, Reporter ; HeLa Cells ; Humans ; Immunosuppressive Agents/chemistry/metabolism/*pharmacology ; Jurkat Cells ; Molecular Sequence Data ; NFATC Transcription Factors ; *Nuclear Proteins ; Oligopeptides/chemistry/metabolism/*pharmacology ; Peptide Library ; Peptides/chemistry/metabolism/*pharmacology ; Phosphorylation ; Recombinant Fusion Proteins/metabolism ; T-Lymphocytes/*drug effects/immunology ; Transcription Factors/*antagonists & inhibitors/chemistry/metabolism ; Transfection
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  • 92
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-01-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lawler, C -- Erbisch, F -- New York, N.Y. -- Science. 1999 Jan 1;283(5398):33-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9917260" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biotechnology ; Mice ; Mice, Transgenic ; *Patents as Topic ; Plants, Genetically Modified/*genetics ; United States
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  • 93
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-10-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shapiro, H T -- New York, N.Y. -- Science. 1999 Sep 24;285(5436):2065.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10523197" target="_blank"〉PubMed〈/a〉
    Keywords: Advisory Committees ; *Bioethical Issues ; Embryo Research ; Embryo, Mammalian/*cytology ; Ethics Committees ; Financing, Government ; Government Regulation ; Humans ; Private Sector ; *Public Policy ; Research/*standards ; Research Support as Topic ; *Stem Cells ; United States
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  • 94
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-06-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Colvin, M -- New York, N.Y. -- Science. 1999 May 28;284(5419):1480.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Duke Comprehensive Cancer Center, Durham, NC 27710, USA. colvi003@mc.duke.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10383327" target="_blank"〉PubMed〈/a〉
    Keywords: Chemistry, Pharmaceutical/history ; Drug Design ; History, 20th Century ; Nobel Prize ; United States
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  • 95
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Landick, R -- New York, N.Y. -- Science. 1999 Apr 23;284(5414):598-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA. landick@macc.wisc.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10328742" target="_blank"〉PubMed〈/a〉
    Keywords: Base Pairing ; Binding Sites ; DNA/chemistry/*metabolism ; DNA-Directed RNA Polymerases/genetics/*metabolism ; Escherichia coli/enzymology/genetics ; Gene Expression Regulation ; Humans ; Models, Genetic ; Mutation ; Nucleic Acid Conformation ; Oligodeoxyribonucleotides, Antisense/chemistry/metabolism ; RNA, Messenger/chemistry/*metabolism ; *Terminator Regions, Genetic ; *Transcription, Genetic ; Viral Proteins/metabolism
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  • 96
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-07-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hagmann, M -- New York, N.Y. -- Science. 1999 Jul 2;285(5424):21-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10428690" target="_blank"〉PubMed〈/a〉
    Keywords: *Genetic Techniques ; *Genome, Human ; Humans ; *Mutation ; *Polymorphism, Genetic
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  • 97
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-04-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, R F -- New York, N.Y. -- Science. 1999 Apr 2;284(5411):33-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10215526" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Arrhythmias, Cardiac/physiopathology ; Calcium/metabolism ; Calcium-Binding Proteins/metabolism ; Cardiac Output, Low/*physiopathology ; Chronic Disease ; *Computer Simulation ; Heart/*physiopathology ; Humans ; *Models, Cardiovascular ; *Myocardial Contraction ; Potassium/metabolism ; Potassium Channels/metabolism
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  • 98
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-05-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hagmann, M -- New York, N.Y. -- Science. 1999 Apr 30;284(5415):723, 725.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10336390" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apoptosis ; Breast Neoplasms/*genetics/pathology ; *Disease Models, Animal ; Female ; *Genes, BRCA1 ; Genes, p53 ; Humans ; Mammary Glands, Animal/pathology ; Mammary Neoplasms, Animal/*genetics/pathology ; Mice ; Mice, Knockout ; Mice, Transgenic ; Mutation
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  • 99
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Whitehead, F -- New York, N.Y. -- Science. 1999 Oct 22;286(5440):681.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10577223" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Evolution ; Education/legislation & jurisprudence/standards ; Kansas ; *Politics ; Religion and Science ; Science/*education
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  • 100
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-04-30
    Description: Notch signaling defines an evolutionarily ancient cell interaction mechanism, which plays a fundamental role in metazoan development. Signals exchanged between neighboring cells through the Notch receptor can amplify and consolidate molecular differences, which eventually dictate cell fates. Thus, Notch signals control how cells respond to intrinsic or extrinsic developmental cues that are necessary to unfold specific developmental programs. Notch activity affects the implementation of differentiation, proliferation, and apoptotic programs, providing a general developmental tool to influence organ formation and morphogenesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Artavanis-Tsakonas, S -- Rand, M D -- Lake, R J -- NS26084/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1999 Apr 30;284(5415):770-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Massachusetts General Hospital Cancer Center, Department of Cell Biology, Harvard Medical School, Building 149, 13th Street, Charlestown, MA 02129, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10221902" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apoptosis ; Cell Communication ; Cell Division ; Cell Nucleus/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins ; Ligands ; Membrane Proteins/*physiology ; Receptors, Cell Surface/*physiology ; Receptors, Notch ; *Signal Transduction ; Transcription, Genetic
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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