ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles  (76)
  • Hypothalamus  (76)
  • Springer  (76)
  • Periodicals Archive Online (PAO)
  • 2005-2009
  • 1980-1984  (50)
  • 1970-1974  (26)
  • Medicine  (76)
  • Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
Collection
  • Articles  (76)
Source
Keywords
Publisher
  • Springer  (76)
  • Periodicals Archive Online (PAO)
Years
Year
Topic
  • Medicine  (76)
  • Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
  • Biology  (76)
  • 1
    Electronic Resource
    Electronic Resource
    Distribution of monoamines in the diencephalon and pituitary of the dogfish, Scyliorhinus canicula L. (1973)
    Springer
    Cell & tissue research 137 (1973), S. 451-469 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Pituitary ; Elasmobranch ; Catecholamine fibres ; Fluorescence microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of monoamines in the diencephalon and pituitary of the dogfish, Scyliorhinus canicula, has been investigated using the histochemical fluorescence technique of Falck and Hillarp (Falck and Owman, 1965). Terminals of monoamine-containing axons were found in the neurointermediate lobe of the pituitary and the axons were traced, by means of nialamide and L-dopa treatment and lesions, to the nucleus medius hypothalamicus. A separate hypothalamic system converging on the anterior median eminence and the occurrence of aminergic cells in the nuclei lobi inferiores and nucleus medius hypothalamicus were similarly demonstrated. Normal fish show a bilateral uncrossed tegmental tract and two areas of catecholamine-containing neurones in modified ependymal organs. The organum vasculosum hypothalami includes both primary catecholamine and 5-hydroxytryptamine-containing cell types whilst the organum vasculosum praeopticum has only the former type. Both organs contain cells which send club-like processes into the third ventricle. The subcommissural organ does not contain monoamines. The role of hypothalamic catecholamine systems in the regulation of pituitary function is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307223
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Monoamines in the liquor-contacting nerve cells in the hypothalamus of the lamprey, Lampetra fluviatilis L. (1973)
    Springer
    Cell & tissue research 144 (1973), S. 549-557 
    Details
    ISSN: 1432-0878
    Keywords: Liquor-contacting neurons ; Hypothalamus ; Lamprey ; Monoamines ; Light and fluorescence microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The hypothalamus of adult lampreys (Lampetra fluviatilis L.) was studied by means of light and fluorescence microscopy (Falck's technique). Some single liquorcontacting nerve cells (LCNC) showing a weak green fluorescence were demonstrated in the ventral part of the third ventricle, above the preoptic recess. Caudally numerous fluorescent LCNC occur in the ventral part of the third ventricle, in the infundibular and in the posterior recess. The LCNC are to be observed between or below the ependymal cells lining the ventricular wall. These cells appear to be of the bipolar type. One process with a club-like protrusion is directed into the ventricular lumen, the other one into the opposite direction. Two types of fluorescent LCNC were distinguished: yellowish green cells, containing catecholamines, and yellowish orange cells, containing 5-hydroxytryptamine. Some similarity between the hypothalamic monoaminergic LCNC in lampreys and LCNC of the paraventricular organ of the other vertebrates was found. The localization, structure and monoaminergic nature of the hypothalamic LCNC in lampreys suggest the possibility, that their monoamines are released into the cerebrospinal fluid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307380
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Luteinizing hormone —Releasing hormone (LH-RH) pathway of the rat hypothalamus revealed by the unlabeled antibody peroxidase-antiperoxidase method (1974)
    Springer
    Cell & tissue research 153 (1974), S. 211-217 
    Details
    ISSN: 1432-0878
    Keywords: Luteinizing hormone-releasing hormone ; Hypothalamus ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Utilizing the unlabeled antibody enzyme method, we report the distribution of hypothalamic elements immunoreactive with antibodies to luteinizing hormone-releasing hormone (LH-RH) in the rat. Immunostained elements, resembling neural processes, were distributed along a pathway corresponding to the tuberoinfundibular tract which appeared to terminate near vascular elements in the external layer of the preand post-infundibular median eminence. No cell bodies stained specifically for LH-RH. Similar topographic arrangements were noted (in coronal and sagittal sections) in diestrous females, ovariectomized females and a hypophysectomized male. The same results were obtained with three different preparations of antisera to LH-RH. Our studies agree with those of other investigators using immunohistochemical techniques as well as with localization studies of LH-RH in the hypothalamus using bioassay and radioimmunoassay. Our results suggest that the unlabeled antibody enzyme technique will have unique value for identifying and tracing fiber systems related to specific functions within the hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226609
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Further data on the existence of a neural pathway from the adrenal gland to the hypothalamus (1974)
    Springer
    Cell & tissue research 153 (1974), S. 559-564 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Afferents ; Adrenal gland ; Protein synthesis ; Auto-radiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effect of unilateral adrenalectomy on the incorporation of tritiated leucine into the ventromedial nucleus of both sides of the rat hypothalamus was studied by light- and electron-microscopical autoradiography. The left adrenal had been removed and 14 days later labeled amino acid was given intravenously. Rats were killed 5, 30, 60 and 120 min after isotope administration. Following unilateral adrenalectomy there is a marked difference in the autoradiographic reaction of both sides of the hypothalamic ventromedial nucleus. On the right side the number of autoradiographic silver grains is much higher than on the left side, the difference being statistically significant for each animal and for each time interval. In accordance with previous findings the data suggest the existence of a neural pathway from the adrenal gland to the hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00231547
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Nucleolus-like bodies in the neuronal cytoplasm of the mouse arcuate nucleus (1973)
    Springer
    Cell & tissue research 146 (1973), S. 319-328 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Mouse ; Arcuate neurons ; Nucleolus-like bodies ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The arcuate nucleus of untreated (control) and castrated adult mice was studied with the electron microscope. Nucleolus-like bodies (NLB) were found in the cytoplasm and occasionally in the dendrites of arcuate neurons. NLB were spherical or ovoid, 0.7–1.5µm in diameter; they were composed of granules 100–150 Å and 200 Å in diameter, and filaments ∼70 Å in diameter. NLB were frequently associated with free ribosomes and cisternae of the rough endoplasmic reticulum. Light microscopic studies with basic dyes and enzymatic digestions showed that these bodies contained some RNA. There was no significant change in the number of NLB in castrated animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02346224
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Ultrastructural and functional aspects of the nucleus infundibularis ventralis in the green frog, Rana esculenta (1973)
    Springer
    Cell & tissue research 144 (1973), S. 191-217 
    Details
    ISSN: 1432-0878
    Keywords: Nucleus infundibularis ventralis ; Hypothalamus ; Rana esculenta ; Gonadotropin releasing factor ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Ultrastructural evidence has been obtained for several nerve cells in the middle and posterior hypothalamus of Rana esculenta, which may be classified as neurosecretory cells. These cells belong to the nucleus infundibularis ventralis, being homologous to the nucleus infundibularis of higher vertebrates. According to the type of dense-core vesicles, two categories of neurosecretory cells were identified in the NIV, type Y and type Z cells. The morphology of these cells and the diameter of their dense-core vesicles suggests a peptidergic nature of the secretory product. Both cell types appeared as bipolar, liquor-contacting neurons, innervated by aminergic axons. The effects of castration and testosterone treatment on the Y cells of the NIV, as well as their localization in the caudal hypothalamus, suggest these cells to be involved in the regulation of the gonadotropic activity of the pars distalis. The presence in the zona externa of the median eminence of axon terminals containing the “Y type dense-core vesicles” is indicative of the release of their secretory product into the portal vessels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307302
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Correlation between microtubular number and transport activity of hypothalamo-neurohypophyseal secretory neurons (1974)
    Springer
    Cell & tissue research 153 (1974), S. 101-113 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Neurohypophysis ; Neurosecretion ; Axoplasmic transport ; Microtubules
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The lower pituitary stalk has been studied in rats given hypertonic saline for four days and in rats with congenital diabetes insipidus (GDI), that is, in two groups of animals in which there is evidence of an increase in the transport of polypeptides down the axons of the tractus hypophyseus. A quantitative ultrastructural analysis of this tract, the first yet made, has demonstrated that in normal animals it is composed of unusually small axons, over half of which are less than 300 nm in diameter. In this tract there is a significant increase in axonal diameter and microtubular content in animals given hypertonic saline for four days. In adult rats with CDI, these changes are even more marked, a feature which is correlated with the fact that in these animals the transport of polypeptides has probably been abnormal since birth. An alteration in the microtubular content of neurons has not previously been observed either in physiologically stressed animals or in diseased animals; such alterations suggest the participation of microtubules in polypeptide transport. The narrow diameter of axons in the tractus hypophyseus of the normal animal raises the possibility of the extravesicular transport of such polypeptides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225449
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Morphological aspects of the hypothalamic-hypophyseal system (1971)
    Springer
    Cell & tissue research 116 (1971), S. 195-204 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamic-hypophyseal system ; Angioarchitecture ; Hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The vascularity of the hypothalamus in rats, cats, and dogs was studied with various injection methods. Particular attention was paid to the capillary architecture of the hypothalamus. The density of the capillary bed in the nuclei of the anterior and medial hypothalamus was studied in male albino rats after filling the cerebral vessels with 5 per cent India ink—gelatin mass. The data obtained were compared with the magnitude-S (projection areas of the capillary meshes of the three-dimensional meshwork) distributions and with the calibres of the capillaries. Distinct inverse correlations were demonstrated between these indices. The objective tests used provided evidence that the peculiar features of the capillary architecture in the various nuclei of the anterior and medial hypothalamus are closely connected with the degree of their vascularity. The rich vascularity of the neurosecretory nuclei is discussed in connection with the peculiarities of their metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00331261
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Ultrastructural features of the lateral preoptic area, median eminence and arcuate nucleus of the rat (1972)
    Springer
    Cell & tissue research 127 (1972), S. 483-491 
    Details
    ISSN: 1432-0878
    Keywords: Lateral preoptic area ; Hypothalamus ; Rat ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The arcuate nucleus, median eminence, and the lateral preoptic area from the brains of aldehyde-perfused male and female rats were examined by electron microscopy. In the lateral preoptic area, three neuronal types are described: a small light neuron, a larger light one, and a dark neuron resembling the larger light one in size and nuclear shape. Many myelinated axons are interposed among single neurons or neuronal pairs. The relationship of structures to each other is discussed. Several observations not previously reported are illustrated from tissue of the arcuate nucleus and median eminence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306867
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Hypothalamic regulation of gonadotropin release in female Japanese quail (1972)
    Springer
    Cell & tissue research 130 (1972), S. 411-428 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Adenohypophysis ; Japanese quail ; Gonadotropins ; Lesions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The control mechanisms of the hypothalamo-hypophysio-ovarian axis were investigated in breeding Japanese quail by means of electrolytic or radiofrequency lesions in various regions of the hypothalamus. Depending on the site of damage to the hypothalamus, two forms of ovarian dysfunction were observed. Lesions in anterior regions of the infundibular nuclear complex or in the anterior division of the median eminence resulted in regression of the ovary and oviduct; all follicles of the ovaries of these birds measured less than 3 mm in diameter. These conditions are interpreted as indicative of cessation of the release of folliclestimulating hormone from the adenohypophysis. Lesions in medial, ventral and posterior regions of the infundibular nuclear complex or in the preoptic region of the hypothalamus resulted in cessation of ovulation, but did not cause complete regression of the ovary and oviduct. In these birds the ovaries and oviducts were reduced somewhat in weight, but the ovarian follicles remained large and laden with yolk. This condition is thought to result from the cessation of the release of luteinizing hormone from the adenohypophysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306952
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 11
    Electronic Resource
    Electronic Resource
    An autoradiographic analysis of hypothalamic magnocellular neurons (1973)
    Springer
    Cell & tissue research 138 (1973), S. 421-437 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Cat ; Magnocellular neurons ; Electron microscopic autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A light and electron microscopic autoradiographic analysis revealed that H3-valine infused into the lateral ventricle of normal and acutely dehydrated cats is preferentially taken up by the supraoptic (SON) and paraventricular nucleus (PVN) of the hypothalamus. Grain counts for these magnocellular neurons in normal unstressed cats were highest at one hour post infusion with a significant fall off by three hours. Uptake by the SON and PVN at one hour exceeded neighboring nuclear groups by a factor of 7 and 4 fold respectively. Electron microscopic autoradiographs from acutely dehydrated cats revealed the presence of emission grains in association with rough endoplasmic reticulum and large osmiophilic neurosecretory vesicles. In view of statistically significant uptake values and rapid turnover of H3-valine by SON and PVN in normal animals, coupled with emission tracks in direct association with underlying neurosecretory product in acutely dehydrated ones, it is speculated that valine may be an amino acid component of one or both of the neurophysins to which neurohypophyseal hormones are non-covalently linked.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307103
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    Organisation scalariforme du réticulum endoplasmique dans certains processus nerveux de l'hypothalamus deGasterosteus aculeatus L. (1970)
    Springer
    Cell & tissue research 106 (1970), S. 61-68 
    Details
    ISSN: 1432-0878
    Keywords: Endoplasmic reticulum ; Neurons ; Hypothalamus ; Fish
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Dans l'hypothalamus de l'Epinoche, certains prolongements nerveux présentent une organisation particulière du réticulum endoplasmique. Des séries de vésicules interconnectées sont disposées en stries transverses espacées de 0,3 à 1,3 μ. Cette organisation particulière du réticulum endoplasmique existe dans les prolongements nerveux de fort diamètre (1 μ), même dans les fibres neurosécrétrices.
    Notes: Summary In some nerve processes of the hypothalamus ofGasterosteus aculeatus, the endoplasmic reticulum displays a special organization. Small interconnected smooth vesicles constitute transverse lines spaced between 0.3 and 1.3 μ. This special organization of the endoplasmic reticulum has been found in nerve processes with a diameter larger than 1 μ even in neurosecretory ones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01027717
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 13
    Electronic Resource
    Electronic Resource
    Somatic spines in the supraoptic nucleus of the rat hypothalamus (1974)
    Springer
    Cell & tissue research 148 (1974), S. 203-211 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Rat ; Supraoptic nucleus ; Ultrastructure ; Somatic spines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Electron microscopic studies of ultrathin serial sections of the perikarya and adjacent neuropil of neurons of the supraoptic nucleus (SON) of the adult male rat revealed varying forms of two types of somatic spines. One type forms synapses with axons passing the cell, the other, without synapses, appears to serve as a buttress or clasp for adjacent neuronal and glial processes. The synapse-bearing spines lack the usual spine apparatus but contain the flocculent substance often seen in spines. The other spines do not exhibit either of these structures. These somatic spines were also seen in Golgi impregnated preparations but the types could not be distinguished. Certain axons synapse either on a somatic spine of the perikarya or penetrate the glial sheath of the neuron and synapse, usually repeatedly, on the soma in an en passant manner.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224582
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 14
    Electronic Resource
    Electronic Resource
    Effect of transection at different levels of hypothalamus on the hypothalamo-hypophysial system of the toad, Bufo bufo, with particular reference to the ultrastructure of the zona externa of the median eminence (1970)
    Springer
    Cell & tissue research 107 (1970), S. 210-233 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Bufo bufo ; Transection ; Median eminence ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ultrastructural changes taking place in the median eminence of Bufo bufo 3 hours to 4 months after transection of the brain at different levels, are described. 5 types of neurons in the zona externa of the median eminence of normal toads are described. All types of neurons degenerate, and profound changes of the ultrastructure of the capillaries are observed after transection just behind, or immediately in front of the optic chiasma. A few neurons containing dense granules with a diameter of about 1,000–1,300 Å remain intact, however. The degeneration following denervation in front of the optic chiasma was considerably delayed compared to degeneration after denervation behind the optic chiasma. After transection more rostral to the optic chiasma, no significant degeneration of the median eminence was observed. The results are discussed with regard to degenerative dynamics and origin of the different nerve types. It is concluded, that all types of neurons terminating in the median eminence, originate at a level between the caudal and rostral parts of the preoptic nucleus, some fibres, however, containing dense, 1,000–1,300 Å granules, originate caudally to the optic chiasma, in the posterior hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335226
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 15
    Electronic Resource
    Electronic Resource
    Effects of estrogen on the cat hypothalamus (1971)
    Springer
    Cell & tissue research 117 (1971), S. 76-86 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Cat ; Estrogen effects ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In this study the ultrastructural features of tissue from the posterior hypothalamic area were investigated. Ovariectomized cats which were either treated with sesame oil placebo or with estrogen for varying periods of time were used. The following observations were noted. 1. The cat that was treated with placebo one month after ovariectomy showed an increase in the number of dense core (granulated) vesicles within neuronal cytoplasm. This observation was not apparent in the cats which were treated with estrogen one month after ovariectomy. 2. In the cat that had been Ovariectomized for two months before treatment with placebo was initiated, axon terminals contained more dense core vesicles than were observed in axonal endings from estrogen-treated cats in the two month ovariectomy group. 3. The tissue from cats that were continuously treated with estrogen for one month after ovariectomy displayed dense-core vesicles in both somata and neuropil. It is suggested that the ultrastructural changes observed were dependent on both the time of initiation and the length of estrogen treatment. 4. It is concluded that the preliminary observations in this study provide anatomical evidence suggesting that estrogen level in the cat may affect the functional activity of the posterior hypothalamic area.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00331103
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 16
    Electronic Resource
    Electronic Resource
    Tanycyte and vascular patterns in the basal hypothalamus of Coturnix quail with reference to their possible neuroendocrine significance (1972)
    Springer
    Cell & tissue research 127 (1972), S. 552-569 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Median eminence ; Coturnix ; Tancyte and vascular patterns
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Im basalen Hypothalamus der Wachtel Coturnix wurde ein gut entwickeltes System von ependymalen Gliazellen mit langen Fortsätzen beobachtet. Diese Ependymzellen (Tanycyten, Horstmann, 1954) reichen bis an die Oberfläche des Gehirns. Die Tanycyten der Eminentia mediana und des ventro-lateralen Hypothalamus bilden eine Verbindung zwischen dem III. Ventrikel und dem portalen Hypophysenkreislauf. Die Fortsätze der ventro-lateralen Tanycyten enden in der Region des Sulcus infundibularis an einem lockeren Gefäßnetz, das sich in das primäre Kapillarnetz des portalen Gefäßsystems der Hypophyse fortsetzt. Das subependymale Kapillarnetz der Eminentia mediana verbindet die Gefäßsysteme der kontralateralen Hypothalamushälften. Hier gibt es keine direkten Verbindungen mit dem portalen Gefäßapparat. Aufgrund von licht- und elektronenmikroskopischen Studien wird das Ventrikelependym von Coturnix in eine dorsale „typische“ Region und in zwei „glanduläre“ Regionen (ventrolateral und ventral) gegliedert. Jedes dieser Gebiete zeigt unterschiedliche Tanycytenformen. Einer der beiden „glandulären“ Tanycytentypen (Typ 3), der im Verein mit dem ventrolateralen „glandulären“ Ependym auftritt, hat keinen Kontakt mit dem III. Ventrikel. Ultrastrukturstudien am „glandulären“ Ependym ergaben keine sicheren Unterschiede zwischen kastrierten und mit Oestrogen oder Testosteron behandelten, sowie zwischen geschlechtsreifen und nicht geschlechtsreifen Wachteln. Die Möglichkeit einer neuroendokrinen Funktion des Tanycyten-Gefäß-Systems wird diskutiert.
    Notes: Summary A well developed system of ependymal glial cells with long basilar processes stretching to the surface of the brain (tanycytes, Horstmann, 1954) has been described in the basal hypothalamus of Coturnix quail. The tanycytes both in the median eminence and the ventro-lateral hypothalamus form a link between the third ventricle and the hypophysial circulation. The processes of the ventro-lateral tanycytes terminate in the region of the infundibular sulcus in apposition to a loose network of vessels which are continuous with the primary plexus of the hypophysial portal system. Within the median eminence, the subependymal capillary network connects the vasculature of the contra-lateral sides of hypothalamus. There are no direct connections with the hypophysial portal vessels. With the aid of the light and electron microscope the ventricular ependyma was divided into a dorsal “typical” region and two “glandular” regions (ventro-lateral and ventral). Each region contains different forms of tanycyte. One of the two forms of tanycyte (designated type 3) associated with the ventro-lateral glandular ependyma has no contact with the third ventricle. Ultrastructural studies on the “glandular” ependyma failed to show any obvious differences between castrated, oestrogen or testosterone implanted, and sexually mature or immature quail. The possibility that the tanycyte-vascular system may have a neuroendocrine role is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306871
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 17
    Electronic Resource
    Electronic Resource
    Ultrastructure of the anuran pars intermedia following severance of hypothalamic connection (1972)
    Springer
    Cell & tissue research 131 (1972), S. 545-557 
    Details
    ISSN: 1432-0878
    Keywords: Pars intermedia ; Hypothalamus ; Anurans ; Hormone release ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ultrastructure of the pars intermedia of Rana catesbeiana tadpoles was studied following isolation from the hypothalamus, in vivo after sectioning of the pituitary stalk, and in vitro after implantation of the pituitary into a piece of tail fin. Both experimental procedures were followed by rapid and sustained skin darkening. Pituitaries from normal light and dark adapted tadpoles served as controls. In 4-hour disinhibited glands, melanotrophs revealed hyperactive Golgi bodies, colloid vesicles (1–2 microns) in close proximity to axon terminals, and no apparent loss of secretory granules. At 24 hours extracellular colloid adjacent to axon terminals was found, and extensive arrays of RER appeared in the melanotrophs. Obvious granule loss from secretory cells occurred within a week, by which time the cytoplasm was occupied by large cisterns of SER and RER and abundant free ribosomes. Dense core vesicles (600–900 Å) in aminergic nerve terminals disappeared shortly after isolation of the pituitary from the hypothalamus, and only decreasing numbers of translucent vesicles (200–300 Å) were found. The functional significance of these changes is discussed, with particular emphasis on the mode of acute hormone release.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306970
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 18
    Electronic Resource
    Electronic Resource
    Ultrastructural aspects of the nucleus infundibularis dorsalis in the caudal hypothalamus of Xenopus laevis (1973)
    Springer
    Cell & tissue research 137 (1973), S. 513-520 
    Details
    ISSN: 1432-0878
    Keywords: Nucleus infundibularis dorsalis ; Hypothalamus ; Xenopus laevis ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ultrastructure of the nucleus infundibularis dorsalis (NID) of the toad Xenopus laevis is described. The nucleus is paired and located in the caudal hypothalamus, dorso-laterally of the caudal end of the paraventricular organ (PVO), and bordering the dorsal wall of the recessus mamillaris. Two cell types can be identified. They are both bipolar and contain dense-core vesicles. Their apical processes protrude into the lumen of the recessus mamillaris, and therefore they are considered liquor-contacting neurons. Because of the Falck-positivity of these cells (Terlou and Ploemacher, 1973) it is assumed that the densecore vesicles contain monoamines. Both cell types probably are sensory cells, although the possibility of their being secretory active as well, cannot be excluded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307227
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 19
    Electronic Resource
    Electronic Resource
    Hypothalamic projections to the amygdala in the cat (1974)
    Springer
    Cell & tissue research 151 (1974), S. 499-508 
    Details
    ISSN: 1432-0878
    Keywords: Limbic system ; Cat ; Amygdaloid body ; Hypothalamus ; Stereotaxic lesions ; Light and electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In order to determine the origin of the hypothalamo-amygdaloid connections in the cat, small lesions were placed at various rostro-caudal levels of the hypothalamus. The animals were sacrificed after a period of 4, 8 or 11 days and the brains stained with the Nauta (1957), Fink and Heimer (1967) or Wiitanen (1969) method for the demonstration of degenerating axons and their terminals. It was observed that the anterior hypothalamic nucleus sends a small projection to the medial subdivision of the central nucleus and to the basal and lateral nuclei of the amygdala. The lateral preoptic area sends a larger projection to the anterior amygdaloid area, both subdivisions of the central and basal nuclei, and to the lateral and medial nuclei. No degeneration was observed in the amygdala following lesions in the medial preoptic area, the ventromedial nucleus or the lateral hypothalamic area caudal to the anterior hypothalamic area. In a series of animals with lateral preoptic lesions, the site of termination of degenerating boutons on neurons of the amygdaloid nuclei was determined and the course of the degenerative process followed over a period ranging from 2 to 15 days. Many of the boutons, especially in the earlier stages of degeneration, appeared to be of the B3 type, containing flattened vesicles and forming symmetrical synaptic contacts with dendrites or somata. With longer post-operative survival times, however, they became increasingly electron dense and shrunken, so that the bouton type could not be determined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222995
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 20
    Electronic Resource
    Electronic Resource
    Transformations of hypothalamic arcuate neurons (1974)
    Springer
    Cell & tissue research 153 (1974), S. 497-515 
    Details
    ISSN: 1432-0878
    Keywords: Arcuate nucleus ; Hypothalamus ; Sexual cycle ; Ribbon-rolls ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Changes in subcellular structures of arcuate neurons correlated in a consistent way with stages of the estrous cycle of the rat. Associated with the rough endoplasmic reticulum short ribbons of moderately electron dense material appeared at metestrus and circular or elliptical bodies termed “ribbon-rolls” at diestrus and proestrus. Although present in proestrus, the ribbon-rolls were smaller at this stage. In a few neurons in diestrous females and in ovariectomized animals one to seven months before perfusion multiple large ribbon-rolls occupied much of the cytoplasm. Also, frequency of dense granules and lysosomes increased in diestrus. The significance of the ribbon-rolls and changes in other structures during the estrous cycle are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00231543
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 21
    Electronic Resource
    Electronic Resource
    The ultrastructure of the medial preoptic area of the rat (1974)
    Springer
    Cell & tissue research 153 (1974), S. 517-530 
    Details
    ISSN: 1432-0878
    Keywords: Medial preoptic area ; Hypothalamus ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The neuronal and glial cell bodies and the neuropil of the medial preoptic area of the rat hypothalamus were studied under the electron microscope. Two different types of neurons are identified on the basis of electron density. These two types differed in a number of ultrastructural features. Three types of nerve terminals based on vesicle morphology are also described, as well as the general structure of the axons, dendrites and synapses in the neuropil. The structure of oligodendrocytes and astrocytes is also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00231544
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 22
    Electronic Resource
    Electronic Resource
    A golgi study on tanycytes and liquor-contacting cells in the posterior hypothalamus of the newt (1974)
    Springer
    Cell & tissue research 154 (1974), S. 151-166 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Urodela ; Tanycytes ; Liquor ; contacting cells ; Golgi methods
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Golgi methods were employed to study neurons and ependymal tanycytes in the posterior hypothalamus of the newt. The tanycytes send a few coarse, spiny or barbed processes towards the pia mater. In the periventricular grey, the neurohistological methods show common neurons, ranging from a multipolar to a plumed organization, and abundant liquor-contacting cells. These cells, possibly neurons, give rise to a process that reaches the cerebro-spinal fluid, and terminates in a spindle-shaped swelling, with a thin thread at its tip. In other cells, the intraventricular endings are bulbous or finger-like. The occurrence of: (1) branches of the liquor-contacting process, running parallel to the infundibular surface; (2) infundibular processes which end at the base or between the ependymal cell bodies; and (3) axons coursing in the same position, all indicates that the subependymal layer is a site for complex intercellular relationships. The significance of liquor-contacting cells and tanycytes is discussed, in view of the possibility that they may represent part of a system for hypothalamic regulation in response to changes in the CSF.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223161
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 23
    Electronic Resource
    Electronic Resource
    Immunocytochemical localization of α-melanocyte-stimulating hormone in the brain of the lizard, Lacerta muralis (1984)
    Springer
    Cell & tissue research 237 (1984), S. 521-524 
    Details
    ISSN: 1432-0878
    Keywords: α-Melanocyte-stimulating hormone ; α-MSH-like peptide ; Immunocytochemistry ; Hypothalamus ; Lizard (Lacerta muralis)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of α-melanocyte-stimulating hormone (α-MSH) was studied in the brain of the lizard Lacerta muralis by means of immunocytochemical staining methods. α-MSH-like containing cells were found in the ventro-lateral preoptic area and the paraventricular and supraoptic nuclei. Some scattered cells staining for α-MSH were also detected in the mesencephalo-diencephalic boundary region, while numerous α-MSH-like nerve fibres were localized in the medial eminence. No reaction was observed after the use of antiserum preabsorbed with synthetic antigen. These findings suggest that an α-MSH-like peptidergic system could possibly be involved in the hypothalamo-hypophysial regulation and/or play a role as neurotransmitter in this animal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00228436
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 24
    Electronic Resource
    Electronic Resource
    Immunohistochemical study on the development of CRF-containing neurons in the hypothalamus of the rat (1984)
    Springer
    Cell & tissue research 238 (1984), S. 539-544 
    Details
    ISSN: 1432-0878
    Keywords: CRF-neurons ; Hypothalamus ; Development, ontogenetic ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Appearance of immunoreactive corticotropin-releasing factor (CRF)-containing neurons was studied in developing hypothalamus of the rat by use of antisera against rat- and ovine CRF. These neurons were first recognized in the lateral and paraventricular nuclei on days 15.5 and 16.5 of gestation, respectively, when antiserum against rat CRF was employed. Antiserum against ovine CRF revealed the cells two days later exclusively in the latter nucleus. In both nuclei, the neurons increased in number with development. The neurons in the paraventricular nucleus appeared to project their immunoreactive processes to the median eminence via the periventricular and lateral pathways. In the median eminence, the immunoreaction with antiserum to rat CRF was first recognized in its anterior portion in the form of dots on day 16.5 of gestation but as beaded fibers in the external layer on day 17.5; these structures increased in amount with development in rostro-caudal direction. Although antiserum to ovine CRF was less potent in immunostainability than antiserum to rat CRF, it also revealed the beaded fibers in the median eminence on day 17.5 of gestation. Since evidence is available that the paraventricular nucleus is involved in corticotropin release, it is concluded that, in rats, the hypothalamic regulatory mechanism controlling the release of corticotropin initially appears on days 16.5–17.5 of gestation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219870
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 25
    Electronic Resource
    Electronic Resource
    Cellular localization of 3H-oestradiol in the hypothalamus (1970)
    Springer
    Cell & tissue research 104 (1970), S. 572-581 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Rat ; Cellular Localization of 3H-Oestradiol ; Autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The hypothalamus of male and female rats, given 0.3 μg/100 g body weight of 6.7-3H-oestradiol-17β and killed 1 hour after the injection, was examined by autoradiography in order to 1) localize the areas and the cells involved in the uptake of the hormone, and 2) study the intracellular localization of the labelled material. Only nerve cells contained radioactive material while glial and ependymal cells were not significantly labelled. In the anterior hypothalamus, labelled nerve cells were concentrated in areas corresponding to nucleus preopticus medialis and nucleus preopticus, pars suprachiasmatica. The nucleus supraopticus was unlabelled. In the medial basal hypothalamus, neurons corresponding to the nucleus arcuatus and the lateral part of the nucleus ventromedialis showed marked labelling. No significant labelling was observed in the nucleus paraventricularis, pars magnocellularis. Although the individual nerve cells varied in their extent of labelling, the major proportion of the silver grains were consistently concentrated over the nuclei. Castration was not found to influence the results. The findings were essentially the same in male and female rats and appear to suggest that oestradiol exerts a direct effect on nerve cells in certain hypothalamic areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335379
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 26
    Electronic Resource
    Electronic Resource
    The uptake of 3H-oestradiol by the anterior hypophysis and hypothalamus of male and female rats (1970)
    Springer
    Cell & tissue research 104 (1970), S. 582-596 
    Details
    ISSN: 1432-0878
    Keywords: Anterior hypophysis ; Hypothalamus ; Rat ; Uptake of 3H-Oestradiol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The anterior hypophysis and hypothalamus of male and female rats given 3H-oestradiol were examined with regard to 1) the kinetics of the uptake of the radioactive material, 2) the chemical nature of the labelled material, and 3) the influence of non-labelled oestradiol-17β, oestradiol-17α and testosterone on the uptake of 3H-oestradiol. The anterior hypophysis was found to concentrate and retain oestradiol in basically the same manner in male and female rats. The pattern of the uptake was similar to that of the uterus and vagina, with a concentration peak 2 hours after the injection. Non-target tissues such as cerebral cortex, liver and blood attained their maximum uptake already 15 minutes after the injection. Thereafter the concentration gradually decreased. The ratio between the concentration of labelled material in the anterior hypophysis and brain cortex gradually increased until a peak was reached at 8 hours in both sexes. In the female, the concentration of labelled material in the anterior hypophysis was then 106.3 times greater than in the brain cortex, while in the male the ratio was 63.2. In the hypothalamus the uptake followed a pattern similar to that of the brain cortex. However, in the former the concentration of labelled material was consistently greater than in the latter. At maximum uptake, registered 4 hours after the injection, the concentration was about two times greater in the hypothalamus than in the cerebral cortex. The neurohypophysis contained, on an average, 1/6 of the amount of radioactive material registered in the anterior lobe one hour after the injection, but it was about two times greater than in the brain cortex. Isolation and identification of the radioactive material in the anterior hypophysis and hypothalamus showed that in both sexes nearly all of it was chemically unchanged oestradiol. Graded doses of non-labelled oestradiol-17β were found to decrease the uptake of 3H-oestradiol in the anterior hypophysis and hypothalamus almost linearly, while the concentration of labelled material in the brain was unaltered. Oestradiol-17α and testosterone were without significant effect on both the pituitary and hypothalamic accumulation of 3H-oestradiol. Therefore, a limited number of binding sites, with a high degree of specificity for oestradiol, appear to exist in both tissues. The results were essentially the same in male and female rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335380
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 27
    Electronic Resource
    Electronic Resource
    Hypothalamic monoamines in lizards (Lacerta) (1980)
    Springer
    Cell & tissue research 205 (1980), S. 95-105 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Monoamines ; Fluorescence microscopy ; Reproduction ; Lizards
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The morphological organization of monoaminergic cells and fibers in the hypothalamus of the lizards Lacerta sicula and Lacerta muralis was investigated by fluorescence histochemistry. An extensive monoaminergic system emanates from the nucleus organi paraventricularis (NOP), a circumventricular organ of the medial and posterior hypothalamus containing numerous monoaminergic perikarya. Fluorescent processes extending from these cells end as intraventricular thickenings. An extensive fiber system presumably arising from the NOP innervates the accompanying nucleus ventromedialis hypothalami (NVH) as well as the nucleus periventricularis hypothalami (NPH) and the median eminence. A monoaminergic fiber path of extrahypothalamic origin enters the preoptic/anterior hypothalamus, terminating in the nucleus paraventricularis (NP). A discrete pathway of catecholaminergic fibers courses through the hypothalamus along the ventral border of the optic tract. Levels of fluorescence intensity are highest in the spring and in castrated animals and lowest in lizards during testicular regression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234446
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 28
    Electronic Resource
    Electronic Resource
    Fetal hypothalamic transplants in the third ventricle of the adult rat brain (1980)
    Springer
    Cell & tissue research 211 (1980), S. 191-206 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Transplants ; Vasopressin ; Median eminence ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Blocks of anterior hypothalamus were transplanted from 19 day-old fetuses of Wistar/Lewis rats into the third ventricle of adult male Brattleboro rats. Physiological changes in graft recipients and in sham-operated animals were monitored daily. Twenty days after surgery, the graft recipients and shamoperated animals were killed and their brains examined by correlative scanning and transmission electron microscopy. Host animals that exhibited both decreased polydipsia and increased urine concentration were found to have viable grafts within the third ventricle. The observed physiological changes suggested that synthesis and release of vasopressin occurred in the transplanted neurons. Grafts were well vascularized by vessels arising from the host hypothalamus. Neurons, with perikarya ranging from 8 to 30 μm in diameter, glial cells, and neurites were located throughout the transplants. A neurohemal contact zone, similar to that normally seen in the median eminence, could not be demonstrated in the grafts. The absence of complete glial and ependymal barriers indicates a relatively close association between cells in the transplants and the cerebrospinal fluid. A large increase in supraependymal neurons and their processes, including an eruption of neurons through the floor of the third ventricle in one animal, was observed in graft recipients but not in shamoperated animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236442
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 29
    Electronic Resource
    Electronic Resource
    Immunohistochemical demonstration of serotonin-containing nerve fibers in the hypothalamus of the monkey, Macaca fuscata (1984)
    Springer
    Cell & tissue research 236 (1984), S. 495-503 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Serotonin ; Neuroendocrine regulation ; Monkey (Macaca fuscata) ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distributional pattern of serotonin-containing nerve fibers in the hypothalamus of the monkey (Macaca fuscata) was analyzed with the use of the peroxidaseantiperoxidase method in conjunction with a highly sensitive and specific anti-serotonin serum. The highest concentrations of serotonin-immunoreactive varicose fibers were found in the nucleus praeopticus medialis, nucleus ventromedialis hypothalami, and the complex of mammillary nuclei (nucleus praemamillaris, supramamillaris, mamillaris medialis et lateralis). However, the nucleus suprachiasmaticus, where numerous serotoninergic fibers have been reported to occur in the rat, appeared to be almost devoid of these fibers. The infundibular stalk, and the intermediate and posterior lobes of the pituitary contained considerable numbers of immunoreactive fibers. The present study provides a morphological basis for possible clarification of the influence of serotoninergic projections on various neuroendocrine mechanisms in primates. Furthermore, an attempt was made to clarify the differences and similarities concerning the distributional patterns of serotoninergic nerve fibers within the monkey hypothalamus in contrast to the rat hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217216
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 30
    Electronic Resource
    Electronic Resource
    Localization of corticotropin-releasing factor-containing neurons in the brain of the domestic fowl (1984)
    Springer
    Cell & tissue research 236 (1984), S. 245-248 
    Details
    ISSN: 1432-0878
    Keywords: Corticotropin-releasing factor ; Immunocytochemistry ; Hypothalamus ; Domestic fowl
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The corticotropin-releasing factor (CRF)-containing neurons were investigated in the brain of the domestic fowl by means of the peroxidase-antiperoxidase technique at the light-microscopic level. The detection of CRF-immunoreactivity was facilitated by silver intensification. CRF-containing perikarya were found in the paraventricular, preoptic and mammillary nuclei of the hypothalamus and in some extrahypothalamic areas (nuclei dorsomedialis and dorsolateralis thalami, nucleus accumbens septi, lobus parolfactorius, periaqueductal gray of the mesencephalon, nucleus oculomotorius ventralis). Immunoreactive nerve fibers and terminals were demonstrated in the external zone of the median eminence and the organum vasculosum of the lamina terminalis. These results indicate that an immunologically demonstrable CRF-neurosecretory system also exists in the avian central nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00216537
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 31
    Electronic Resource
    Electronic Resource
    Typology, distribution and development of the catecholamine-containing neurons in the chicken brain (1984)
    Springer
    Cell & tissue research 237 (1984), S. 67-79 
    Details
    ISSN: 1432-0878
    Keywords: Catecholamine-containing neurons ; Brainstem ; Hypothalamus ; Chicken ; Chick embryo
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Fluorescence-histochemical investigations by use of the FAGLU method show the presence of several groups of catecholamine (CA)-containing neurons in the chicken brain. The distribution, shape and orientation of the fluorescent perikarya as well as the number and orientation of primary dendrites have been systematically examined. In the chick embryo, the first neurons displaying specific catecholamine fluorescence are identifiable on the 9th day of incubation. The onset of this type of specific fluorescence is consistent with biochemical data reported in the literature for the chick embryo. The main complexes of CA-containing cell bodies, shown at medullary, pontine and mesencephalic levels, display a pattern of distribution that is quite similar in both the chicken and the rat. In the hypothalamus of chick embryos and newly hatched chicks, CA-containing neurons have been localized within the paraventricular organ, and the periventricular and mammillary regions. By the fourth week after hatching, within the hypothalamus the paraventricular organ alone continues to display fluorescent neurons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229201
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 32
    Electronic Resource
    Electronic Resource
    Fluorescent granules in the guinea-pig hypothalamus and their possible relation to neurosecretory substance (1970)
    Springer
    Cell & tissue research 103 (1970), S. 559-569 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Guinea-pig ; Fluorescence ; Neurosecretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Sections of guinea-pig hypothalamus stained by various methods have been studied under bright-field and fluorescence microscopy to determine the characteristics of refractile granules originally observed in fixed tissue stained for cholinesterases but also seen in unfixed, unstained material. When sections of fresh tissue or tissue fixed in formaldehyde: Na2SO4 were examined by fluorescence microscopy, the granules emitted with a wave-length between 600 and 620 mμ. The density and distribution of the granules closely paralleled that of one of the components that stained with the aldehyde-fuchsin and chrome-alum techniques for neurosecretory substance; granules were absent, however, from the area characterized by Herring substance, and from the stained perikarya and beaded axons of the supraoptic and paraventricular nuclei. The granules were most numerous in the median eminence and infundibular nuclei. Their concentration was about “average” in mature males and in lactating and hypophysectomized females; they were more abundant in late pregnancy and after ovariectomy and were particularly plentiful some weeks after hysterectomy. They were virtually absent from immature males and females. The possible relation of the granules to releasing factors or to vasotocin-like neurosecretory material is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00337528
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 33
    Electronic Resource
    Electronic Resource
    Histochemical demonstration of acetylcholinesterase in the hypothalamus of the female guinea-pig (1970)
    Springer
    Cell & tissue research 103 (1970), S. 570-588 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Guinea-pig ; Acetylcholinesterase ; Reproduction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of acetylcholinesterase (AChE) in the hypothalamus of the female guinea pig has been examined histochemically. Activity was found in neurones of the supraoptic, paraventricular and infundibular nuclei; in the lateral hypothalamic area, in cells dorsomedial to the fornix at the level of the paraventricular nucleus and in a large group of cells surrounding the fornix at the level of the in-fundibular nucleus. A small well-stained group of cells, not identified in histological preparations, was present ventral to the paraventricular nucleus. The neuropil stained at the lateral border of the paraventricular nucleus and in the medial mammillary, suprachiasmatic and dorsomedial nuclei. The walls of some blood vessels stained; activity was particularly strong in vessels in the preoptic area and at the base of the median eminence. Nerve fibres on blood vessels ventral to the hypothalamus also stained. The degree of enzyme activity in the cell groups was compared in immature, pregnant, lactating, ovariectomized and hysterectomized animals. The greatest variation occurred in the infundibular nucleus. Hypophysectomy markedly reduced staining in the supraoptic nucleus. The possibility that AChE may be involved in the elaboration or transport of releasing factors is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00337529
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 34
    Electronic Resource
    Electronic Resource
    Structural and microspectrofluorometric studies on glial cells from the periventricular and arcuate nuclei of the rat hypothalamus (1980)
    Springer
    Cell & tissue research 211 (1980), S. 503-510 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Glia structure ; Fluorescence spectroscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Fluorescence spectroscopy and electron microscopic techniques have been employed to investigate a class of glial cells that is characterized by the presence in their cytoplasm of large fluorescing inclusions that stain with paraldehyde-fuchsin or chrome-hematoxyline-alum. In the periventricular nucleus the cells have been identified as a population of astrocytes whose inclusions emit an orange-red fluorescence. In the arcuate nucleus there are, in addition to an overwhelming majority of such astrocytes, also some microglial cells with similar characteristics. The ability of the latter to emit any kind of fluorescence has not yet been established. The fluorescence maximum of these astrocytic inclusions was found to be at 640 nm when excited at 405 nm. The data obtained suggest that the fluorescence observed is due to the presence of porphyrins in the astrocytic inclusions. In the majority of our electron microscopic pictures the inclusions lack a bounding membrane. By contrast, neuronal lipofuscin has an outer membrane. In cryostat sections, the lipofuscin emits a yellow fluorescence when excited at 400–410 Onm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234404
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 35
    Electronic Resource
    Electronic Resource
    Distribution of immunoreactive somatostatin in the primate hypothalamus (1983)
    Springer
    Cell & tissue research 233 (1983), S. 69-80 
    Details
    ISSN: 1432-0878
    Keywords: Somatostatin ; Hypothalamus ; Immunocytochemistry ; Human ; Rhesus monkey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Immunocytochemical methods were used to compare the localization of somatostatin (SRIF) in the human and rhesus monkey hypothalamus. The distribution of SRIF-containing cell bodies and fibers is similar in the two species. Perikarya are located predominantly in the periventricular region and to a lesser extent in the ventromedial nucleus. Fibers occur in dense clusters within the periventricular region, ventromedial nucleus, arcuate nucleus, median eminence, and pericommissural area of both species. Analysis of serial sections suggests that fibers originate from cells in the periventricular region, extend ventrally through the ventromedial and arcuate nuclei to terminate around the portal vessels of the infundibular stalk, and thereby participate in the regulation of anterior pituitary function. Somatostatinergic fibers are also found surrounding non-immunoreactive perikarya in the ventromedial nucleus and periventricular region of both primates. This arrangement may support somatostatin's postulated role as a neurotransmitter or neuromodulator. The strong similarity between the localization of hypothalamic SRIF in the human and rhesus monkey supports the use of the rhesus monkey as a model for the study of somatostatin as a neuroendocrine regulator in the human.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222233
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 36
    Electronic Resource
    Electronic Resource
    Distribution of immunoreactive thyrotropin-releasing hormone in the forebrain and hypophysis of the bullfrog, Rana catesbeiana (1983)
    Springer
    Cell & tissue research 233 (1983), S. 507-516 
    Details
    ISSN: 1432-0878
    Keywords: Thyrotropin releasing hormone ; Rana catesbeiana ; Hypothalamus ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of immunoreactive thyrotropin-releasing hormone (TRH) in the forebrain and hypophysis of Rana catesbeiana was studied by means of specific radioimmunoassay and immunohistochemistry based on peroxidase-antiperoxidase (PAP) techniques. A relatively high concentration of immunoassayable TRH is present in the hypothalamus. Immunoreactive TRH cell bodies are found in the anterior part of the preoptic nucleus, the dorsal infundibular nucleus, the nucleus of diagonal band of Broca, and the medial part of the amygdala. Immunoreactive nerve terminals are observed in the neurohypophysis and the external layer of the median eminence, where the terminals are in close contact with the capillary loops of the hypophyseal portal vessels. The possible role of TRH in the frog brain is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00212220
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 37
    Electronic Resource
    Electronic Resource
    Ultrastructural characteristics of vasopressin-containing neurons in the paraventricular nucleus of the hypothalamus (1983)
    Springer
    Cell & tissue research 234 (1983), S. 125-134 
    Details
    ISSN: 1432-0878
    Keywords: Vasopressin ; Immunocytochemistry ; Electron microscopy ; Hypothalamus ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Vasopressin-containing neurons, identified by immunocytochemistry, are located predominantly in the posterior magnocellular division of the paraventricular nucleus of the rat hypothalamus. By electron microscopy, the immunoreaction product is seen within the cell bodies and neuronal processes. In the perikarya and dendritic processes, the immunoreactive material is associated primarily with neurosecretory granules. Axonal processes, identified by their content of microtubules and accumulation of neurosecretory granules, show the immunoreaction product in association with both of these organelles. Afferent axo-dendritic, axo-somatic and putative axo-axonic synapses with immunostained vasopressinergic neurons can be identified. The presynaptic profiles do not contain immunoreactive material. This study contributes to the ultrastructural characterization of vasopressinergic neurons in the paraventricular nucleus and of their afferent synaptic input.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217406
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 38
    Electronic Resource
    Electronic Resource
    Alteration by estrogen of the nucleoli in nerve cells of the rat hypothalamus (1984)
    Springer
    Cell & tissue research 235 (1984), S. 485-489 
    Details
    ISSN: 1432-0878
    Keywords: Ventromedial nucleus ; Hypothalamus ; Ultra-structure ; Nucleoli ; Estrogen effects ; Chromatin ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Estrogen is accumulated from the blood by nerve cells in the ventromedial nucleus of the hypothalamus and can facilitate female reproductive behavior by acting on this region of the brain. This cell group was examined in ovariectomized female rats, given estrogen or control treatment, by use of light and electron microscopy. A significantly greater portion of the nerve cells in the estrogen-treated animals had protuberances on their nucleolar surfaces, apparent under the light microscope. The fine structure of such protuberances included dense, aggregated material, which is shown to contain DNA by the sodium tungstate staining technique. Because increased numbers of such protuberances were found in nuclei of cells of the experimental group where previous studies demonstrated a significant increase in ultrastructural signs of biosynthetic activity, they may be associated with increased RNA synthesis. Thus, they could indicate, ultrastructurally, increased synthetic rates for RNA in nerve cells through which estrogen promotes reproductive behavior.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226943
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 39
    Electronic Resource
    Electronic Resource
    Non-neuronal cells of rat hypothalamus in dissociated cell culture (1984)
    Springer
    Cell & tissue research 237 (1984), S. 161-168 
    Details
    ISSN: 1432-0878
    Keywords: Vasopressin-neurophysin ; Non-neuronal cells ; Cell culture ; Hypothalamus ; Growth factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The neurophysin that is biosynthesised in association with the neurohypophysial hormone vasopressin (vasopressin-neurophysin) affects the growth and DNA synthesis of rat hypothalamic non-neuronal cells in culture. Over a narrow range of concentrations vasopressin-neurophysin stimulated growth, as assessed by increase in cell numbers, about five-fold, in conditions where fetal calf serum concentration was limiting (0.2% fetal calf serum). Maximum stimulation occurred in the presence of 20 to 30 ng vasopressin-neurophysin per ml of medium. DNA synthesis was increased by a factor of three in the presence of 30 ng vasopressin-neurophysin per ml of medium. At least two populations of non-neuronal hypothalamic cells were present in the cultures, and these were both affected by vasopressin-neurophysin. This study allows the suggestion that neurophysin may be acting as a growth-regulating factor at its release site, playing a part in the interactions of neurones and glial cells in the hypothalamo-neurohypophysial system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229212
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 40
    Electronic Resource
    Electronic Resource
    Mapping of neurons in the central nervous system of the guinea pig by use of antisera specific to the molluscan neuropeptide FMRFamide (1984)
    Springer
    Cell & tissue research 237 (1984), S. 575-586 
    Details
    ISSN: 1432-0878
    Keywords: FMRFamide ; Pancreatic polypeptide ; Hypothalamus ; Neuropeptide immunocytochemistry ; Brain mapping ; Guinea pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Immunoreactive neurons were mapped in the central nervous system of colchicine-treated and untreated guinea pigs with the use of two antisera to the molluscan neuropeptide FMRFamide 1. These antisera were especially selected for their incapability to react with peptides of the pancreatic polypeptide family. Only one group of perikarya was stained by both antisera; this group was mainly located in the nucleus dorsomedialis hypothalami and extended to the nucleus paraventricularis and nucleus periventricularis hypothalami. The perikarya were found to project fibers to all regions of the hypothalamus, to the septum, nucleus proprius striae terminalis, nucleus paraventricularis thalami, nucleus centralis thalami, nucleus reuniens, medial, central and basal amygdala, area praetectalis, area tegmentalis ventralis of Tsai, substantia grisea centralis mesencephali, formatio reticularis mesencephali, nucleus centralis superior, locus coeruleus, nuclei parabrachiales, nucleus raphe magnus, A 5-region, vagus-solitarius complex, ventral medulla, nucleus spinalis nervi trigemini, and substantia gelatinosa of the spinal cord. In many brain regions FMRFamide-immunoreactive processes were found in close contact with blood vessels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00228442
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 41
    Electronic Resource
    Electronic Resource
    Substance P-related peptides in the hypothalamus of Amphibia (1980)
    Springer
    Cell & tissue research 211 (1980), S. 241-250 
    Details
    ISSN: 1432-0878
    Keywords: Substance P-related peptides ; Immunohistochemistry ; Hypothalamus ; Amphibia (Triturus cristatus, Xenopus laevis, Rana esculenta)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The occurrence of Substance P-(SP)-related peptides in the hypothalamus of three species of Amphibia (newt, clawed, toad, frog) was studied immunohistochemically employing the indirect immunofluorescence method or a double-step technique (indirect immunofluorescence followed by the peroxidase-antiperoxidase complex method). SP-like immunopositive fibers are seen throughout the hypothalamus. They are especially abundant in the preoptic area and in the outer zone of the median eminence, suggesting a role of SP-related peptides in the hypothalamo-hypophysial regulation in these animals. Some SP-like neurons are seen in the posterior hypothalamus and in the preoptic area. In the newt, such SP-like immunopositive neurons occur frequently in the preoptic periventricular grey.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236447
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 42
    Electronic Resource
    Electronic Resource
    Effects of tunicamycin on the hypothalamo-neurohypophysial system of the rat (1981)
    Springer
    Cell & tissue research 217 (1981), S. 199-210 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Neurohypophysis ; Neurophysin ; Secretion ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Intracisternal injections of tunicamycin, an inhibitor of glycosylation, decreased the incorporation of [35S]cysteine into the neurophysins in the rat neurohypophysis. Histochemical and immunocytochemical studies showed that there was no concomitant decrease in the amount of secretory product in the perikarya of the hypothalamo-neurohypophysial neurones. Indeed there was an increase, although this was not associated with neurosecretory granules as judged electron-microscopically. Tunicamycin led to the formation of socalled “colloid droplets” which were immunopositive and of which the ultrastructural correlates appeared to be product-filled dilatations of the rough endoplasmic reticulum. The observations are interpreted to suggest that glycosylation plays a rôle in the packaging of secretory material in the hypothalamo-neurohypophysial system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233838
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 43
    Electronic Resource
    Electronic Resource
    Topography of retinal axons in the diencephalon of goldfish (1984)
    Springer
    Cell & tissue research 238 (1984), S. 529-538 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Thalamus ; Visual centers ; Horseradish-peroxidase histochemistry ; Teleosts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The projections of horseradish peroxidase-filled axons from each quadrant of the retina were studied to determine whether retinal projections of goldfish are topographically organized in diencephalic target nuclei. A distinct topography of the dorsal, nasal, ventral and temporal retina exists in the lateral geniculate nucleus and in the dorsolateral optic nucleus of the thalamus. The projections of retinal quadrants show minimal spatial overlap in each of these nuclei. The suprachiasmatic nucleus of the hypothalamus is extensively innervated by ventral retinal fibers, whereas the nucleus is sparsely innervated by fibers from the other three retinal quadrants. A rudimentary topography also exists in the pretectum where the dorsal pretectal area receives projections primarily from the ventral retina and the ventral pretectal area receives projections mostly from the dorsal retina. These data show that retinal projections to some diencephalic nuclei are topographically organized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219869
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 44
    Electronic Resource
    Electronic Resource
    The preoptic area of the domestic fowl (1980)
    Springer
    Cell & tissue research 210 (1980), S. 85-94 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Domestic fowl ; Preoptic area ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Numerous secretory parvocellular perikarya were found in the preoptic region of the domestic fowl (Gallus gallus). The dense-core secretory vesicles belong to two categories: vesicles with a diameter of (i)80–90 nm and (ii) 110–140nm. Scattered magnocellular elements display larger dense-core granules. The parvocellular neurons form unit-like clusters, showing also zones of direct apposition of neuronal membranes. The surrounding neuropil is rich in synaptic structures, formed by at least three types of axon terminals, distinguishable on the basis of vesicular morphology. These observations confirm the findings in other avian species. The hypothetical function of this system of peptidergic neurons in the rostral hypothalamus of birds is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232144
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 45
    Electronic Resource
    Electronic Resource
    Brain lesions and short-term endocrine effects of monosodium L-glutamate in goldfish, Carassius auratus (1980)
    Springer
    Cell & tissue research 212 (1980), S. 429-442 
    Details
    ISSN: 1432-0878
    Keywords: Goldfish ; Glutamate ; Gonadotropin ; Prolactin ; Nucleus lateral tuberis ; Hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Monosodium L-glutamate (MSG) was injected intraperitoneally into goldfish at a dosage of 2.5mg/g body weight. At 24 h post-injection there was a marked hypertrophy and edema in the region of the nucleus lateralis tuberis (NLT) from the anterior margin of the pituitary stalk through to the posterior end of the NLT, irrespective of the sex of the goldfish. A similar hypertrophy and edema occurred ventral to the anterior commissure in the preoptic region in the anterior-ventral nucleus preopticus periventricularis (NPP). At 6 h post-injection a slight vacuolization was evident in these two regions, and at two days the hypertrophy and edema had abated from the extent observed at 24 h post-injection. At five and eight days post-injection only necrotic cells were found in the affected NLT region, but only a small band of necrotic cells was evident in the anterior-ventral preoptic region. No other brain lesions were evident. Serum levels of gonadotropin (GtH) were increased at 6 h, 24 h, and two days after treatment with MSG, but were similar to control values at five, seven and eight days after MSG in male and female goldfish. Exocytosis of small dark secretory granules in gonadotrophs was evident at 24 h after MSG in a fish with a somewhat greater increase in serum GtH than usually found. The time course of increased serum GtH levels postinjection of MSG is consistent with the observed time course of hypertrophy and atrophy of NLT neurons; the increase in serum levels of GtH is interpreted to reflect a stimulation of release of GtH-releasing factor from neurons in the NLT. Electron microscope investigation indicates that prolactin cells have increased secretory and synthetic activity from 24 h through to seven days post-injection of MSG. The mechanism for stimulation of the prolactin cells by MSG is not known. No other changes in activity of adenohypophysial secretory cells were found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236508
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 46
    Electronic Resource
    Electronic Resource
    Cytodifferentiation of the paraventricular nucleus in the chick embryo (1983)
    Springer
    Cell & tissue research 229 (1983), S. 281-297 
    Details
    ISSN: 1432-0878
    Keywords: Paraventricular nucleus ; Hypothalamus ; Development ; Golgi study ; Ultrastructure ; Chick embryo
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The developmental changes in the cytoarchitecture of the hypothalamic paraventricular nucleus of the chick embryo were studied with particular emphasis on the differentiation of the magnocellular neurons. These cells can be distinguished from the parvocellular elements starting from stages 34–35 (Hamburger and Hamilton 1951) in Golgi-impregnated specimens. At the same stages, electron microscopy reveals dense-core granules, resembling the characteristic elementary granules of the neurosecretory material in the cytoplasm of the larger neurons. In addition, a few immature synapses were observed on these magnocellular perikarya. The present observations suggest that the early onset of neurosecretion in this area may be neurally regulated during early phases of development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00214976
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 47
    Electronic Resource
    Electronic Resource
    GABAergic neurons in dissociated cultures of rat hypothalamus, septum, and midbrain (1983)
    Springer
    Cell & tissue research 229 (1983), S. 685-694 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Cultures ; (3H)GABA ; GAD (glutamic acid decarbocylase)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cultures of dissociated tissue blocks from 18 day-old rat embryos containing either septum plus anterior hypothalamus, retrochiasmatic hypothalamus, or midbrain, were maintained for 8–29 days in vitro. GABAergic neurons were visualized by incubation with (3H)γ-aminobutyric acid followed by autoradiography and by immunocytochemistry using an antiserum against glutamic acid decarboxylase. Positive neurons were of variable shapes and sizes. Labeled neurons in the three cultured regions represented 3.4, 1.1 and 1.7%, respectively, of all neurons. Apart from a few exceptions, autoradiographic labeling and immunocytochemical staining coincided. Glial cells did not stain and showed very low grain densities. Radioactivity could be released from preloaded cultures upon depolarization by 50 mM potassium and 100 μM Veratridine. The demonstration of GABAergic neurons in cultures that are known to contain a variety of peptidergic neurons opens up the possibility of studying the interaction between the two classes of neurons in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00207706
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 48
    Electronic Resource
    Electronic Resource
    Central connections of the pineal organ in the three-spined stickleback, Gasterosteus aculeatus L. (Teleostei) (1983)
    Springer
    Cell & tissue research 232 (1983), S. 141-155 
    Details
    ISSN: 1432-0878
    Keywords: Epiphysis cerebri ; Epithalamus ; Thalamus ; Hypothalamus ; Tegmentum mesencephali ; HRP-tracing ; Gasterosteus aculeatus L. (Teleostei)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Central connections of the pineal organ of the three-spined stickleback, Gasterosteus aculeatus L., were studied by the use of horseradish peroxidase (HRP) for anterograde tracing. The pineal tract terminates bilaterally in the habenular nuclei, area praetectalis, dorsal and ventral thalamic nuclei, periventricular hypothalamus, and dorsal tegmentum. Furthermore, fibers were traced into the rostral hypothalamus, tuberal nuclei and deep tegmentum. No pinealopetal connections were observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222380
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 49
    Electronic Resource
    Electronic Resource
    Hypothalamic LHRH and plasma LH levels after electrical stimulation of the deafferented medial basal hypothalamus (1983)
    Springer
    Cell & tissue research 234 (1983), S. 209-217 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Deafferentation ; LHRH ; LH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The medial basal hypothalamus (MBH) of female rats was surgically isolated on the morning of proestrus and luteinizing hormon (LH) levels in the blood were determined before and after electrochemical stimulation (ECS) of the disconnected arcuate-median eminence (ARC-ME) region either on the same afternoon (Group 1) or on the 5th postoperative day (Group 2). Animals of Groups 3 and 4 were stimulated and sampled for LH on the 5th or 10th postoperative day, respectively, these rats having been primed with 5 μg estradiol injected daily throughout the experimental period. ECS resulted in a significant rise of plasma LH level in Group 1 and caused full ovulation as evaluated by the presence of ova found the next morning in the Fallopian tubes. Rats of Groups 2–4 failed to show any changes in plasma LH, and no ovulation was observed following ECS. Immunohistochemical examination of the brains revealed that axons staining for the luteinizing hormone-releasing hormone (LHRH) in the ARC-ME region remained at control levels 3 days after deafferentation (e.g. Group 1), whereas a marked decrease or complete absence of these structures was observed 8 or 13 days following surgical isolation of the MBH (e.g. Groups 2–4). These studies strongly support the view that no LHRH synthesizing perikarya are located within the MBH of the rat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217414
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 50
    Electronic Resource
    Electronic Resource
    Immunoreactive material resembling ovine prolactin in perikarya and nerve terminals of the rat hypothalamus (1982)
    Springer
    Cell & tissue research 226 (1982), S. 121-131 
    Details
    ISSN: 1432-0878
    Keywords: Rat brain ; Hypothalamus ; Prolactin ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The presence of prolactin (PRL)-like material is demonstrated in the brain of rats with the aid of anti-ovine PRL (oPRL) IgG as primary antibody in the unlabeled antibody-enzyme method. Immunoreactive deposits are visualized as an intraneuronal constituent with a widespread distribution in the hypothalamus and neural lobe of the pituitary. Dense networks of reactive nerve terminals derived from two prominent fibre tracts, a ventral (VHT) and a dorsal hypothalamo-neurohypophysial tract (DHT) are seen. The VHT is confined to the median eminence and pars oralis tuberis, the DHT to the pars caudalis tuberis. Both fibre tracts pass through the infundibular stalk into the neural lobe. The origin of the immunoreactive nerve terminals can be elucidated only to some extent. The VHT gives off beaded fibres entering the ependymal and glandular layer of the median eminence. Immunoreactive perikarya are observed in the supraoptic nucleus, the paraventricular nucleus, the anterior hypothalamic nucleus, the anterior commissural nucleus, the preoptic nucleus and the interstitial nucleus of the stria terminalis. A few of the immunoreactive perikarya are observed in close connection with brain vessels and the ependymal cells of the third ventricle. The results indicate that the anti-oPRL has a unique region specificity implying that only a segment of the mammalian PRL molecule is present in these nuclei of the brain. Fragments of PRL may function as neuromodulators or neurotransmitters in the rat brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217087
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 51
    Electronic Resource
    Electronic Resource
    Ultrastructure of the “smooth endoplasmic reticulum cell” in the nucleus recessus lateralis of Salmo gairdneri Richardson (1982)
    Springer
    Cell & tissue research 227 (1982), S. 221-224 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Nucleus recessus lateralis ; Smooth endoplasmic reticulum ; Teleosts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The fine structure of one of the cellular components of the nucleus recessus lateralis of trout is described. These cells have an enormously developed smooth endoplasmic reticulum which makes their identification easy. The relationship of this cell type with the ventricular cavity, neighbouring cells and the presence of synaptic contacts with these cells are also described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00206343
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 52
    Electronic Resource
    Electronic Resource
    Immunocytochemical localization of somatostatin and vasotocin in the brain of the Pacific hagfish, Eptatretus stouti (1983)
    Springer
    Cell & tissue research 229 (1983), S. 541-550 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Hagfish ; Somatostatin neurons ; Vasotocin neurons ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The brain of the Pacific hagfish, Eptatretus stouti, was studied immunocytochemically using antisera against somatostatin (SRIH), arginine vasopressin (AVP), and adrenocorticotropic hormone (ACTH). SRIH-immunoreactive perikarya were distributed bilaterally in the postoptic nucleus and in the hypothalamic nucleus. Although several short, stained fibers were observed in the vicinity of the perikarya, SRIH-immunoreactivity was not found in the neurohypophysis, nor in other parts of the brain. On the other hand, presumed arginine vasotocin (AVT) perikarya were distributed in an arc-shaped region extending from the posterior part of the preoptic nucleus to the anterior-most end of the hypothalamic nucleus and projected their fibers to the neurohypophysis. Most presumptive AVT perikarya were located close to the paired prehypophysial arteries near the anterior end of the postoptic nucleus. In the neurohypophysis, abundant presumptive AVT-fibers terminated in the posterior dorsal wall, although some fibers terminated in the anterior dorsal wall and only a few fiber endings were found in the ventral wall. No ACTH-positive cells were detected in the hagfish brain or in the pituitary gland.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00207697
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 53
    Electronic Resource
    Electronic Resource
    Immunohistochemical identification of neurons containing corticotropin-releasing factor in the rat hypothalamus (1983)
    Springer
    Cell & tissue research 230 (1983), S. 239-246 
    Details
    ISSN: 1432-0878
    Keywords: CRF neurons ; Hypothalamus ; Immunohistochemistry ; PAP ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A specific rabbit anti-CRF serum and the immunoperoxidase technique were used to show that CRF-containing neurons are mainly distributed in the paraventricular and supraoptic nuclei of the rat hypothalamus. In addition, immunoreactive neurons are scattered in other hypothalamic regions. These neurons are 20–30 μm in diameter. From the present and previous investigations it may be concluded that the hypothalamic magnocellular nuclei, i.e., paraventricular and supraoptic, and other hypothalamic accessory nuclei, are the producing sites not only for vasopressin and oxytocin, but also for corticotropin-releasing factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00213802
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 54
    Electronic Resource
    Electronic Resource
    CSF-contacting and other somatostatin-immunoreactive neurons in the brains of Anguilla anguilla, Phoxinus phoxinus, and Salmo gairdneri (Teleostei) (1983)
    Springer
    Cell & tissue research 233 (1983), S. 319-334 
    Details
    ISSN: 1432-0878
    Keywords: CSF-contacting neurons ; Somatostatin immunocytochemistry ; Hypothalamus ; Entopeduncular nucleus ; Pretectal area ; Tegmentum ; Teleosts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A system of somatostatin-immunoreactive neurons was demonstrated in the brains of the eel, Anguilla anguilla, the European minnow, Phoxinus phoxinus, and the rainbow trout, Salmo gairdneri, by means of the light-microscopic indirect immunoperoxidase technique. In the anterior periventricular nucleus, somatostatin-immunoreactive cerebrospinal fluid (CSF)-contacting neurons display intensely stained intraventricular dendritic protrusions, perikarya, and axonal processes. The latter taper into a somatostatin-immunoreactive fiber plexus extending to the infundibulum, the proximal neurohypophysis, and the lateral and mammillary recesses. In addition, somatostatin-immunoreactive neurons were demonstrated in the magnocellular preoptic, entopeduncular and dorsolateral thalamic nuclei, further in the pretectal area and the ventrolateral tegmentum. Somatostatin-immunoreactive fiber bundles project via the stria medullaris toward the habenular nucleus; they also course in the dorsomedial-ventrolateral direction at the level of the pretectal-tegmental area, and within the ventral and dorsal tegmentum. The presence of somatostatin in a variety of different neurons of the teleost brain is discussed in connection with their tentative inhibitory function. The CSF-contacting neurons of the anterior periventricular nucleus are supposed to function as sensors that pass information from the CSF to the somatostatin system of the hypothalamus and/or other components of the neuroendocrine apparatus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238299
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 55
    Electronic Resource
    Electronic Resource
    Ontogenetic studies on the topographical heterogeneity of somatostatin-containing neurons in rat hypothalamus (1983)
    Springer
    Cell & tissue research 233 (1983), S. 347-354 
    Details
    ISSN: 1432-0878
    Keywords: Development ; Somatostatin neuron ; Hypothalamus ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ontogeny of the somatostatin-containing neuron system was investigated by light-microscopic immunohistochemistry. During development, immunoreactive somatostatin-containing neurons arise from three discrete regions of the neuroepithelium of the third ventricle and show a chronological difference. The neurons are first evident within the third ventricle floor on day 12.5 of gestation; they move thereafter to the arcuate nucleus. The second generation occurs in the dorsal region of the arcuate nucleus during days 17.5–19.5; these neurons migrate sequentially into the arcuate-ventromedial nuclear region. The third generation is recognized in the neuroepithelial cell layer of the rostral hypothalamus on day 17.5 of gestation; these cells move to the periventricular area. This latter generation is most prominent during days 3–6 after birth, and some of the cells are seen sporadically even up to day 20. The first two generations give rise to the somatostatin neuron system in the arcuate-ventromedial nuclear region, while the latter gives rise to that in the rostral periventricular region in the adult rat hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238301
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 56
    Electronic Resource
    Electronic Resource
    The preoptic area of the domestic fowl (1980)
    Springer
    Cell & tissue research 207 (1980), S. 395-406 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Domestic fowl ; Preoptic area ; Golgi study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The preoptic area of the domestic fowl (Gallus gallus) was studied by means of the Golgi technique. At least two regions can be recognized: (i) a medial and (ii) a lateral area, clearly distinguishable laterally from the adjacent telencephalic regions. The dendritic organization of the preoptic area is quite uniform. The neurons can be classified as isodendritic elements. The magnocellular elements are few and irregularly scattered mostly in the periventricular grey of the medial preoptic area. Of relevant interest is also the observation of some bipolar and horizontal neurons in the dorsal part of the medial preoptic area, near the anterior commissure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224616
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 57
    Electronic Resource
    Electronic Resource
    Ultrastructure and immunocytochemistry of neurons in the supraoptic and paraventricular nuclei of the lizard Liolaemus cyanogaster (1980)
    Springer
    Cell & tissue research 207 (1980), S. 463-477 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Neurosecretion ; Ultrastructure ; Neurophysin ; Lizard
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The supraoptic (SON) and paraventricular (PVN) nuclei of the lizard Liolaemus cyanogaster c. were studied by use of histochemical, immunocyto-chemical and electron microscopic methods. The immunofluorescence staining for neurophysin was applied to methacrylate-embedded material before and after treatment of the sections with urea and trypsin. Pseudoisocyanine was applied to sections previously used for immunocytochemistry. The ultrastructural study showed that the SON and PVN neurons possess neurosecretory granules (nsg), distributed throughout the perikaryon, and large (2 to 12 μm) electron-dense droplets located within dilatations of the cisternae of the rough endoplasmic reticulum. Whereas the perikaryon (nsg) and the secretory droplets are stainable with pseudoisocyanine, only the former displays immunoreactivity for neurophysin. However, after treating the sections with urea and trypsin, the same secretory droplets become immunoreactive. It is suggested that the secretory droplets are sites of storage for the precursor of neurophysin, and that the tryptic digestion either triggers its conversion into neurophysin or exposes its immunoreactive sites. Based on the ultrastructure and the histochemical behavior of the secretory droplets, it is also postulated that they contain, in addition to peptides, a glycoprotein component.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224620
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 58
    Electronic Resource
    Electronic Resource
    Glycoprotein secretion in the hypothalamo-neurohypophyseal system of the rat (1980)
    Springer
    Cell & tissue research 209 (1980), S. 399-422 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Neurohypophysis ; Glycoprotein ; 3H-fucose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Although the secretory products of the hypothalamoneurohypophyseal system are not glycoproteins, synthesis and migration of these macromolecules occur within its secretory neurons. After being labeled with 3H-fucose in the Golgi apparatus, newly synthesized glycoproteins migrate to secretion granules, lysosomes and the plasma membrane of the secretory neurons, as demonstrated by quantitative electron-microscopic radioautography. Secretion granules bearing newly synthesized glycoproteins migrate to the pars nervosa, the labeling pattern of which was studied in rats killed from 4 h to 14 days after the isotope injection. Most of the silver grains were observed to overly the secretory axons. Labeling of pituicytes was negligible and the number of silver grains over the perivascular spaces was about 10% of the total at certain postinjection intervals. In the secretory axons, most of the silver grains were seen to overly the secretion granules. The proportion of silver grains over the different portions of the secretory axons changed with time. At the longer intervals, the percentage of silver grains increased over the nerve swellings (including Herring bodies) and decreased concomitantly in the undilated portions of the axons and in the nerve endings. This labeling pattern conforms with observations on the secretion products. Water deprivation increased the release of neurosecretion as well as glycoproteins from the pars nervosa. However, glycoproteins inside the Herring bodies were not easily releasible. There was a parallel decrease in the amount of secretion granules and 3H-fucose-labeled glycoproteins indicating that the glycoproteins are predominantly a constituent of the granule content. Some newly synthesized glycoproteins were probably also used in the renewal of the axonal membrane. The labeling of smooth vesicles in nerve endings was discussed. In conclusion, most of the glycoproteins synthesized in the perikarion of the hypothalamic secretory neurons migrate inside secretion granules along the axon to the pars nervosa where they are secreted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234755
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 59
    Electronic Resource
    Electronic Resource
    Neuronal systems immunologically related to the somatostatin system in the garden dormouse (1980)
    Springer
    Cell & tissue research 209 (1980), S. 455-472 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Somatostatin ; Immunohistochemistry ; Adrenalgland ; Garden dormouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cells and fibers containing somatostatin (SRIF) or SRIF-like peptides were detected immunocytochemically in the brain of the garden dormouse (Eliomys quercinus L.). The periventricular preoptic nucleus and the paraventricular nucleus encompass a component of the SRIF-immunoreactive hypothalamoinfundibular and hypothalamo-neurohypophyseal systems. The suprachiasmatic, ventromedial and arcuate nuclei contain a number of SRIF-positive cells and receive a rich SRIF innervation. The extrahypothalamic systems containing SRIF can be subdivided into the following groups: (1) Afferents, the cellular origin of which is not always clearly evident, i.e., fibers of the septum, the lateral preoptic area, the thalamus, the superior olivary nucleus, the mesencephalic gray matter, and the subfornical organ; (2) dispersed cells with short projections (neocortex, caudate nucleus, putamen); (3) scattered cells with short projections (nucleus accumbens) or innervating remote territories (nucleus interpeduncularis); (4) vascular organ of the lamina terminalis, a neurohemal area comparable to the median eminence. These observations lead to a theory of a functional bipotentiality of the somatostatin molecule. Immunocytological results depend on the antisera employed, the type of fixation and the experimental conditions. Adrenalectomy is followed by an accumulation of immunoreactive material in all SRIF-containing systems of the brain. These results clearly indicate that SRIF participates in the function of the CRF-ACTH-adrenal axis. The endocrine disturbance induced by adrenalectomy appears to modify the activity of both the neurohormonal and neuromodulator components of the SRIF system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234758
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 60
    Electronic Resource
    Electronic Resource
    Differing immunoreactivities of somatostatin in the cortex and the hypothalamus of the rat (1980)
    Springer
    Cell & tissue research 212 (1980), S. 457-464 
    Details
    ISSN: 1432-0878
    Keywords: Somatostatin immunoreactivity ; Cortex ; Hypothalamus ; Light and electron microscopic immunocytochemistry ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Using an antibody against somatostatin (antiserum “F”), two somatostatin-immunoreactive systems, (i) a hypothalamic and (ii) an extrahypothalamic cortical system, are demonstrated in the rat. Another antiserum raised against somatostatin (antiserum “BS 102”) stains only the axons but not the perikarya of the hypothalamic system; the cortical somatostatin system does not react with this antiserum. The electron microscopic findings do not allow decision whether the above-mentioned hypothalamic and cortical neurons possess a common prohormonal form of somatostatin, immunoreactive only with antiserum “F”. They show, however, that the granules in both neuronal systems differ considerably; in the cortical neurons they measure approximately 65 nm in diameter, in the hypothalamic neurons 90–120 nm in diameter. Thus, both somatostatin systems are different and independent from one another.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236510
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 61
    Electronic Resource
    Electronic Resource
    The hypothalamic magnocellular system in the domestic fowl (1981)
    Springer
    Cell & tissue research 215 (1981), S. 113-131 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Neurosecretory cells ; Domestic fowl ; Golgi study ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the rostral hypothalamus of the domestic fowl, the magnocellular neurosecretory nuclei show a peculiar differentiation. Golgi studies of the supraoptic and paraventricular nuclei of the fowl reveal at least two major cell types: 1) large multipolar neurons, and 2) small interneurons. Golgi impregnations provide a detailed cytoarchitectural picture of the large-sized cells; the latter may well correspond to the neurosecretory cells demonstrated in the same regions by selective staining, and immunocytochemical and electron microscopical techniques. Electron microscopically, neuronal perikarya are observed to contain variable amounts of neurosecretory granules (100–200 nm in diameter; mean diameter of 160 nm) scattered throughout the cytoplasm. The diameters of these granules do not differ statistically in the two principal nuclear areas examined. The perikarya of these neurons display only a few axosomatic synapses containing electron-lucent and dense-cored vesicles (70–90 nm in diameter). Numerous nerve terminals of this type also end on the dendritic ramifications in the surrounding neuropil.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236253
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 62
    Electronic Resource
    Electronic Resource
    Cytoarchitectonic pattern of the hypothalamus in the cobra, Naja naja (1981)
    Springer
    Cell & tissue research 217 (1981), S. 505-529 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Cytoarchitecture ; Magnocellular (“AF-positive”) nuclei ; Parvocellular (“AF-negative”) nuclei ; Cobra, Naja naja
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution and cytoarchitectonic pattern of the magno- and parvocellular hypothalamic nuclei of the cobra, Naja naja, are described at the light-microscopic level. With respect to their tinctorial affinity to paraldehyde fuchsin (AF) as a representative of the Gomori-type of stains, the magnocellular neurons belong to the “AF-positive” and the parvocellular neurons to the “AF-negative” elements. In addition to the supraoptic and paraventricular nuclei proper, two accessory aggregations of magnocellular neurons, the nucleus retrochiasmaticus and nucleus circularis, can be identified. Although in a peculiar location, they may be regarded as subunits of the supraopticoparaventricular neurosecretory complex. As many as 22 “AF-negative” nuclear areas are identified in the hypothalamus of the cobra. The nucleus periventricularis hypothalami of earlier authors is subdivided into several circumscribed neuronal complexes. The nucleus arcuatus, nucleus hypothalamicus lateralis and nucleus lateralis recessus infundibuli are well developed. An attempt is made to interpret the significance of these nuclei on a comparative and phylogenetic basis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219361
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 63
    Electronic Resource
    Electronic Resource
    Electron-microscopic immunocytochemical demonstration of separate vasotocinergic, mesotocinergic and somatostatinergic neurons in the hypothalamic magnocellular preoptic nucleus of the frog (1981)
    Springer
    Cell & tissue research 218 (1981), S. 7-12 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Rana temporaria ; Vasotocinergic neurons ; Mesotocinergic neurons ; Somatostatinergic neurons ; Electron microscopic immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The hypothalamic magnocellular preoptic nucleus of Rana temporaria was studied at the electron-microscopic level with the use of the unlabeled antibody peroxidase-antiperoxidase complex (PAP) technique. The magnocellular preoptic nucleus of R. temporaria contains at least three different types of neurons: (1) Vasotocinergic neurons, (2) mesotocinergic neurons, and (3) neurons that contain either somatostatin or an immunologically related peptide. The present results are in complete agreement with those of previous immunocytochemical studies conducted at the light microscopic level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210086
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 64
    Electronic Resource
    Electronic Resource
    Immunocytochemical localization of neurotensin-containing neurons in the hypothalamus of the japanese quail, Coturnix coturnix japonica (1981)
    Springer
    Cell & tissue research 218 (1981), S. 29-39 
    Details
    ISSN: 1432-0878
    Keywords: Neurotensin ; Hypothalamus ; Coturnix quail ; Immunocytochemistry ; Neuropeptide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The hypothalamus of Japanese quail, Coturnix coturnix japonica, has been studied by means of the peroxidase-antiperoxidase immunocytochemical method, with the use of antibodies to synthetic neurotensin (NT). A number of immunoreactive neuronal perikarya occur in the medial preoptic nucleus of the rostral hypothalamus and a few in the accessory part of paraventricular nucleus and dorsal portion of the infundibular nucleus. Some of them correspond to the parvocellular neurons previously identified tentatively as neurosecretory (Mikami et al. 1975, 1976). Large numbers of immunoreactive neuronal fibers are found in the preoptic area, which extend as a remarkable fiber tract from this area to the ventral septal area and to the subfornical organ. A few immunoreactive fibers also extend ventrocaudally to the infundibular nucleus and to the neural lobe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210089
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 65
    Electronic Resource
    Electronic Resource
    The hypothalamus of Lacerta sicula R. (1982)
    Springer
    Cell & tissue research 223 (1982), S. 61-71 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Lizard (Lacerta sicula R.) ; Golgi methods
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The posterior (caudal) hypothalamus of the lizard, Lacerta sicula R. was investigated by means of Golgi methods. The periventricular grey is formed mainly by isodendritic bipolar and multipolar neurons, while in the lateral hypothalamus a more stellate form of neuronal elements is encountered. CSF-contacting neurons are restricted to the tuberal area and to the paraventricular organ. In the latter area they are highly differentiated and endowed with laterally branched processes. The overall pattern of the lizard hypothalamus (organization of neuropil, lateral nuclei, appearance of cell clusters, morphology of the neuronal elements) represents an intermediate stage in the phylogenetic development of the hypothalamus, being more advanced than the amphibian stage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00221499
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 66
    Electronic Resource
    Electronic Resource
    Immunocytochemical localization of substance P in the neurohypophysis and hypothalamus of the mouse compared with the distribution of other neuropeptides (1982)
    Springer
    Cell & tissue research 223 (1982), S. 533-544 
    Details
    ISSN: 1432-0878
    Keywords: Substance P ; Immunocytochemistry ; Neurohypophysis ; Hypothalamus ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Substance-P immunoreactivity has been located in semithin sections of mouse hypothalami and pituitaries and compared with the distribution of other hypothalamic peptides. In the mouse, nerve fibres and terminals reacting with antibodies against substance P (SP) were detected both in the external zone of the median eminence (ME) and in the neural lobe of the pituitary. Immunoreactive SP (ISP) axons of the ME did not react with antibodies against other peptides, i.e. arginine-vasopressin (AVP), oxytocin (OT), somatostatin and enkephalin, and were also negative with an antibody to serotonin. In the neural lobe, SP immunostaining occurred in AVP but not in OT axons. In the hypothalamus, ISP axons were widespread but conspicuously lacking in areas containing AVP neurones, i. e. in the suprachiasmatic nucleus and the clusters of AVP cells in the SO and PV nuclei. In contrast, multiple ISP endings were seen in contact with OT neurones. Immunoreactive cell bodies, only detected after colchicine treatment, belonged to two distinct classes of neurones: 1) single AVP neurones of the SO and PV nuclei; 2) specific (staining only for SP) neurones, scattered or grouped in different areas of the hypothalamus, not showing relationship with any circumscribed nucleus. These results reinforce the opinion that SP can be released as a neurohormone into the vascular portal system and can directly affect the pars distalis. The presence of immunoreactive SP in the neural lobe, which has not been reported in species other than the mouse, may have a different physiological significance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00218474
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 67
    Electronic Resource
    Electronic Resource
    Cerebrospinal fluid-contacting neurons and other somatostatin-immunoreactive perikarya in brains of tadpoles of Xenopus laevis (1982)
    Springer
    Cell & tissue research 224 (1982), S. 693-697 
    Details
    ISSN: 1432-0878
    Keywords: Somatostatin ; Immunocytochemistry ; CSF-contacting neurons ; Hypothalamus ; Xenopus laevis, tadpoles ; Amphibia, Anura
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In untreated tadpoles of Xenopus laevis, stage 60 (Nieuwkoop and Faber 1956), somatostatin-immunoreactive perikarya and fiber networks are already discernible in the pallium and the septum, as well as in the anterior and posterior hypothalamus. In addition, somatostatin-immunoreactive cerebrospinal fluid (CSF)-contacting neurons were found in the periventricular gray of the most caudal division of the ventral tuber cinereum. The results are discussed with respect to the inhibitory influence of the system of CSF-contacting and other somatostatin-immunoreactive neurons on the anterior pituitary and other target sites, especially during the climax of metamorphosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00213765
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 68
    Electronic Resource
    Electronic Resource
    Immunohistochemical localization of the luteinizing hormone releasing hormone (LHRH)-containing structures in the central nervous system of the domestic fowl (1982)
    Springer
    Cell & tissue research 227 (1982), S. 451-458 
    Details
    ISSN: 1432-0878
    Keywords: Domestic fowl ; Hypothalamus ; LHRH-neurosecretion ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The location of LHRH-containing neuronal elements was investigated in the domestic fowl by means of immunohistochemical techniques. LHRH antisera were raised against synthetic LHRH in the rabbit. The antiserum used in the present study cross-reacted with LHRH of mammalian and avian tissues. LHRH-immunoreactive perikarya are located in the preoptic and in the septal areas, and in the bulbus olfactorius; however, no LHRH-immuno-reactive perikarya were found in the tuberal part of the hypothalamus. LHRH-immunoreactive fibers course from these areas toward the median eminence mainly along the wall of the third ventricle in the form of a periventricular network. Originating from the same cell groups other fibers run caudally immediately above the optic chiasma, forming the median bundle of the tractus preoptico-infundibularis. The third bundle running toward the OVLT is named the tractus preoptico-terminalis. In addition to these structures, LHRH-containing fibers and terminals were also present in different regions of the limbic system, in the dorsal part of the hippocampus, in the tuberculum and bulbus olfactorius, as well as in the optic lobe, nuclei commissurales tectales, organon subcommissurale, periaqueductal area, and pars ventralis mesencephali. The general distribution of the LHRH system in the chicken corresponds principally to that described previously in rodents (Sétáló et al. 1976, 1978). However, some subtle differences were demonstrated between the location of the LHRH system in birds and mammals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210899
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 69
    Electronic Resource
    Electronic Resource
    Light and electron microscopic observation on the appearance of immunoreactive LHRH in perinatal rat hypothalamus (1980)
    Springer
    Cell & tissue research 213 (1980), S. 465-474 
    Details
    ISSN: 1432-0878
    Keywords: LHRH ; Immunohistochemistry ; Light and electron microscopy ; Median eminence ; Hypothalamus ; Perinatal rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The appearance and localization of LHRH were studied in the developing hypothalamus of perinatal rats using the unlabelled antibody method. By light microscopy, immunoreactive LHRH was first detected as brown dots on day 18.5 of gestation in the OVLT and on day 19.5 in the median eminence, respectively. When the median eminence was examined by the preembedding immunohistochemistry technique for electron microscopy, the occurrence of immunoreactive LHRH fibers could be demonstrated on day 18.5. These fibers were thin and very occasionally encountered near the surface of the lateral regions of the median eminence. The axoplasm contained a few immunopositive secretory granules and also extragranular immunoreactive products. With development, a gradual increase was noted both in number and size of nerve fibers with a concomitant accumulation of secretory granules within the axoplasm. A possible physiological significance of LHRH is discussed in relation to the onset of hypothalamo-hypophysial system in fetal life.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237891
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 70
    Electronic Resource
    Electronic Resource
    Retinal projections in the electric catfish (Malapterurus electricus) (1980)
    Springer
    Cell & tissue research 213 (1980), S. 497-503 
    Details
    ISSN: 1432-0878
    Keywords: Visual system ; Teleost ; Thalamus ; Optic tectum ; Hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The poorly developed visual system of the electric catfish was studied with silver-degeneration methods. Retinal projections were entirely contralateral to the hypothalamic optic nucleus, the lateral geniculate nucleus, the dorsomedial optic nucleus, the pretectal nuclei including the cortical nucleus, and the optic tectum. The small size and lack of differentiation of the visual system in the electric catfish suggest a relatively small role for this sensory system in this species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237894
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 71
    Electronic Resource
    Electronic Resource
    Localization by immunofluorescence of a gastrin-like substance in the brain of the rainbow trout, Salmo gairdneri (1981)
    Springer
    Cell & tissue research 214 (1981), S. 247-255 
    Details
    ISSN: 1432-0878
    Keywords: Gastrin-like substance ; Teleost brain ; Hypothalamus ; Immunofluorescence microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary With the aid of an indirect immunofluorescence technique neurones containing a gastrin-like substance were identified in the brain of Salmo gairdneri. The perikarya of these neurones appear to be located along the periventricular part of the nucleus lateralis tuberis between the hypophysial stalk and the most rostral tip of the saccus vasculosus. The fibres of these perikarya run rostrally toward the hypophysis, where they can be followed in the protrusions of the neurohypophysis into the proximal pars distalis. Here the bundle of immunoreactive fibres divides into numerous smaller bundles and into single fibres. Immunohistochemical specificity tests have shown this immunoreactive substance to belong to the gastrin group, sharing an antigenic determinant with cholecystokinin (CCK) and pentagastrin (common aminoacid sequence Trp-Met-Asp-Phe). A possible function of these gastrin (or CCK)-containing neurones in the rainbow trout is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00249209
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 72
    Electronic Resource
    Electronic Resource
    Immunoreactive ACTH/β-endorphin neurons in the tubero-infundibular hypothalamus of rats (1982)
    Springer
    Cell & tissue research 224 (1982), S. 303-314 
    Details
    ISSN: 1432-0878
    Keywords: ACTH/β-endorphin neurons ; Synapse ; Hypothalamus ; Immunohistochemistry ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the preinfundibular portion of male rat hypothalamus, the arcuate-median eminence region was examined after staining with anti-porcine ACTH 1-39 serum. In several cases, anti-β-endorphin serum was also employed. Both sera stain the same cell bodies. The cell bodies of the immunoreactive neurons are scattered in the subependymal layer, arcuate nucleus and lateral tuberal region. Fibers originating from these cell bodies are distributed extensively throughout these regions. They make synaptic contacts on immunonegative fibers in the arcuate nuclei, or terminate directly in the perivascular space in the internal layer of the median eminence. The fibers, however, are very scarce in the external layer of the median eminence, and do not directly terminate on the neurovascular contact surface. These findings suggest that the ACTH/β-endorphin neuronal system may serve neuronally and humorally as an intrahypothalamic constituent of the hypothalamic pituitary regulation system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00216875
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 73
    Electronic Resource
    Electronic Resource
    Retinofugal projections in the eel, Anguilla anguilla L. (Teleostei), visualized by the cobalt-filling technique (1982)
    Springer
    Cell & tissue research 225 (1982), S. 507-524 
    Details
    ISSN: 1432-0878
    Keywords: Visual system ; Thalamus ; Optic tectum ; Hypothalamus ; Eel (Teleostei)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The retinofugal projections in the eel were studied by use of the cobalt-filling technique. The optic tract projects contralaterally to the hypothalamic optic nucleus, the anterior periventricular nucleus, the lateral geniculate nucleus, the dorsomedial optic nucleus, four pretectal recipient areas, the optic tectum, and the tegmentum. Small ipsilateral projections were demonstrated in the hypothalamic optic nucleus, the dorsomedial optic nucleus, and the optic tectum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00214801
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 74
    Electronic Resource
    Electronic Resource
    Immunohistochemical localization of vasoactive intestinal polypeptide(VIP)-containing neurons in the hypothalamus of the Japanese quail, Coturnix coturnix (1982)
    Springer
    Cell & tissue research 226 (1982), S. 13-26 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Vasoactive intestinal polypeptide (VIP) ; Immunohistochemistry ; Japanese quail ; Tuberohypophysial system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry. Numerous VIP-immunoreactive perikarya are distributed in the caudal portion of the nucleus infundibularis (n. tuberis) and nucleus mamillaris lateralis, and sparse in the preoptic area, nucleus supraopticus and nucleus paraventricularis. Dense localization of immunoreactive-VIP fibers is observed in the external layer of the median eminence, in close contact with the primary portal capillaries. The main origins of these fiber terminals are VIP-immunoreactive perikarya of the nucleus infundibularis. These neurons are spindle or bipolar and extend one process to the ventricular surface and another to the external layer of median eminence. They are CSF-contacting neurons and apparently constitute the tubero-hypophysial tract that links the third ventricle and the hypophysial portal circulation. VIP-reactive neurons in the nucleus mamillaris lateralis also project axons to the external layer of the median eminence, constituting the posterior bundle of the tuberohypophysial tract. Numerous VIP-immunoreactive perikarya occur also in the nucleus accumbens/pars posterior close to the lateral ventricle. They are also CSF-contacting neurons extending a process to the lateral ventricle. There are moderate distributions of VIP-reactive fibers in the area ventralis and in the area septalis. Ultrastructurally, the immunoreactive products against VIP are found in the elementary granules, 75–115 nm in diameter, within the nerve fibers in the median eminence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217078
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 75
    Electronic Resource
    Electronic Resource
    LHRH-immunoreactive cells in the brain of the three-spined stickleback, Gasterosteus aculeatus L. (Gasterosteidae) (1982)
    Springer
    Cell & tissue research 226 (1982), S. 695-699 
    Details
    ISSN: 1432-0878
    Keywords: LH-FSH releasing hormone ; Hypothalamus ; Thalamus ; Tegmentum mesencephali ; Teleosts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cells immunoreactive with an anti-LHRH serum were visualized in the brain of the three-spined stickleback, Gasterosteus aculeatus, by means of the PAP technique. Positive cells were found in a periventricular position in the nucleus praeopticus pars magnocellularis, the nucleus dorsomedialis thalami, the nucleus ventromedialis thalami, the nucleus periventricularis posterior, and in the periventricular dorsomedian tegmentum. These cells were frequently observed to contact the CSF.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00214796
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 76
    Electronic Resource
    Electronic Resource
    Testosterone-induced alterations in the reactivity pattern of the neurons in the arcuate nucleus of male mice (1983)
    Springer
    Cell & tissue research 229 (1983), S. 183-189 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Arcuate nucleus ; Testosterone ; Karyometry ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of testosterone administration on the hypothalamic arcuate nucleus were studied in adult male mice by means of karyometry. Four animals per group were sacrificed 1, 2, and 3 h after intramuscular injection of 100 μg testosterone propionate/100 g body weight. The nuclear diameter of neurons was measured in serial coronal sections. Testosterone induced an increase in the nuclear diameter of neurons located in the dorsal and medial periventricular zones of the arcuate nucleus. The neurons exhibiting the greatest changes in nuclear diameter were situated in the rostral portion of the nuclear area examined. In the central portion of the arcuate nucleus no response to testosterone was found. The present data support previous observations showing mosaically arranged nerve-cell groups in this hypothalamic nucleus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217890
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...