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Localization by immunofluorescence of a gastrin-like substance in the brain of the rainbow trout, Salmo gairdneri

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Summary

With the aid of an indirect immunofluorescence technique neurones containing a gastrin-like substance were identified in the brain of Salmo gairdneri. The perikarya of these neurones appear to be located along the periventricular part of the nucleus lateralis tuberis between the hypophysial stalk and the most rostral tip of the saccus vasculosus. The fibres of these perikarya run rostrally toward the hypophysis, where they can be followed in the protrusions of the neurohypophysis into the proximal pars distalis. Here the bundle of immunoreactive fibres divides into numerous smaller bundles and into single fibres. Immunohistochemical specificity tests have shown this immunoreactive substance to belong to the gastrin group, sharing an antigenic determinant with cholecystokinin (CCK) and pentagastrin (common aminoacid sequence Trp-Met-Asp-Phe). A possible function of these gastrin (or CCK)-containing neurones in the rainbow trout is discussed.

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Authors and Affiliations

  1. Stichting Opleiding Leraren, Afd. biologie, Archimedeslaan 16, Postbus 14007, 3508, SB Utrecht, The Netherlands

    C. D. Notenboom, J. C. Garaud, J. Doerr-Schott & M. Terlou

  2. Unité 61 de l'INSERM, Strasbourg, France

    C. D. Notenboom, J. C. Garaud, J. Doerr-Schott & M. Terlou

  3. Laboratoire de Cytologie Animale, Strasbourg, France

    C. D. Notenboom, J. C. Garaud, J. Doerr-Schott & M. Terlou

  4. Zoölogisch Laboratorium, State University of Utrecht, Utrecht, The Netherlands

    C. D. Notenboom, J. C. Garaud, J. Doerr-Schott & M. Terlou

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  1. C. D. Notenboom
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  2. J. C. Garaud
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  3. J. Doerr-Schott
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  4. M. Terlou
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Notenboom, C.D., Garaud, J.C., Doerr-Schott, J. et al. Localization by immunofluorescence of a gastrin-like substance in the brain of the rainbow trout, Salmo gairdneri . Cell Tissue Res. 214, 247–255 (1981). https://doi.org/10.1007/BF00249209

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  • DOI: https://doi.org/10.1007/BF00249209

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