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  • Springer  (121.610)
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  • 2020-2024  (48)
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  • 1
    facet.materialart.
    Unbekannt
    Springer
    Publikationsdatum: 2024-01-10
    Beschreibung: The volume offers insights into new theoretical approaches that should make it possible to analyse cultural change through migration. It focuses on concrete activities in local contexts and their significance for national narratives. Finally, it presents newer approaches in migration studies that use artistic methods and work with cultural institutions to drive cultural change.
    Beschreibung: Der Band bietet Einblick in neue theoretische Ansätze, die ermöglichen sollen, kulturellen Wandel durch Migration zu analysieren. Er richtet den Blick auf konkrete Aktivitäten in lokalen Kontexten und deren Bedeutung für nationale Narrative. Abschließend präsentiert er neuere Ansätze in der Migrationsforschung, die sich künstlerischer Methoden bedienen und mit kulturellen Institutionen zusammenarbeiten, um kulturelle Veränderung voranzutreiben.
    Schlagwort(e): Migration; Postmigration; kultureller Wandel; Kunst; Kultur ; ÖFOS 2012 -- SOZIALWISSENSCHAFTEN (5) -- Soziologie (504) -- Soziologie (5040) -- Migrationsforschung (504021) ; ÖFOS 2012 -- GEISTESWISSENSCHAFTEN (6) -- Andere Geisteswissenschaften (605) -- Andere Geisteswissenschaften (6050) -- Kulturwissenschaft (605004) ; Migration; postmigration; cultural change; art; culture ; ÖFOS 2012 -- SOCIAL SCIENCES (5) -- Sociology (504) -- Sociology (5040) -- Migration research (504021) ; ÖFOS 2012 -- HUMANITIES (6) -- Other Humanities (605) -- Other Humanities (6050) -- Cultural studies (605004)
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Publikationsdatum: 2024-01-30
    Beschreibung: The ability to use data produced by different sources (social networks, governments, weather sensors etc.) is widely recognized as a key to capitalize the value of data. In the scientific field, such usage may incredibly boost the innovation and foster new discoveries. However, one of the main hurdles is currently represented by the difficulties in achieving the required interoperability to provide integrated access to multi-disciplinary data. The current work presents a metadata-driven approach that uses in a combined way metadata, semantics, and services as key components for providing integrated access to heterogeneous data sources. The integration occurs within a central data integration system, which is driven by a rich metadata catalogue and that can present the data provided by the different data sources in a harmonised way to the end user, by means of RESTful APIs. A real application demonstrating metadata-driven semantic and service interoperability for achieving homogeneous access to multi-disciplinary heterogeneous data sources is illustrated in the case of EPOS, a Research Infrastructure for Solid Earth Science. The advantages in terms of ease of maintenance, of flexibility in plugging different standard without perturbating communities’ long-lasting technical practices, and of ability to track provenance are discussed. Future work for providing open-source implementation of a system built following the proposed approach is also envisaged.
    Beschreibung: Published
    Beschreibung: 235–247
    Beschreibung: OST5 Verso un nuovo Monitoraggio
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: book chapter
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Publikationsdatum: 2024-01-30
    Beschreibung: The Shapes Constraint Language (SHACL) has been recently introduced as a W3C recommendation to define constraints for validating RDF graphs. In this paper a novel SHACL-driven multi-view editor is presented: SHAPEness. It empowers users by offering them a rich interface for assessing and improving the quality of metadata represented as RDF graphs. SHAPEness has been developed and tested in the framework of the European Plate Observing System (EPOS). In this context, the SHAPEness features have proven to be a valuable solution to easily create and maintain valid graphs according to the EPOS data model. The SHACL-driven approach underpinning SHAPEness, makes this tool suitable for a broad range of domains, or use cases, which structure their knowledge by means of SHACL constraints.
    Beschreibung: Published
    Beschreibung: 274–288
    Beschreibung: OST5 Verso un nuovo Monitoraggio
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: book chapter
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Publikationsdatum: 2024-04-29
    Beschreibung: When a lava flow enters a body of water, either a lake, sea, river or ocean, explosive interaction may arise. However, when it is an 'a'ā lava flow entering water, a more complex interaction occurs, that is very poorly described and documented in literature. In this paper, we analysed the 2–4 ka San Bartolo lava flow field emplaced on the north flank of Stromboli volcano, Italy. The lava flow field extends from ~ 650 m a.s.l. where the eruptive fissure is located, with two lava channels being apparent on the steep down to the coast. Along the coast the lava flow field expands to form a lava delta ~ 1 km wide characterised by 16 lava ‘Flow’ units. We performed a field survey to characterise the features of lava entering the sea and the associated formation of different components and magnetic measurements to infer the flow fabrics and emplacement process of the lava flow system. We measured the density, porosity and connectivity of several specimens to analyse the effect of lava-water interaction on the content in vesicles and their connectivity and conducted a macroscopic componentry analysis (clast count) at selected sites to infer the character of the eroded offshore segment of the lava flow field and its component flow units. The collected data allowed us to define the main components of a lava delta fed by 'a'ā lava flows, with its channels, littoral units, ramps, lava tubes, and inflated pāhoehoe flows controlled by the arterial 'a'ā flow fronts. The spatial organisation of these components allowed us to build a three-step descriptive model for 'a'ā entering a water. The initial stage corresponds to the entry of channel-fed 'a'ā lava flow into the sea which fragments to form metric blocks of 'a'ā lava. Continued lava supply to the foreshore causes flow units to stall while spreading over this substrate. Subsequent 'a'ā lava flow units ramp up behind the stalled flow front barrier. Lava tubes extending through the stalled flow barrier feed the seaward extension of a bench made of several pāhoehoe flow units.
    Beschreibung: Open access funding provided by Università degli Studi di Torino within the CRUI-CARE Agreement. This project is a part of RS PhD project. This research was funded by MIUR ex-60% attributed to EZ and PhD grants-Budget 10% attributed to RS. Also, it was partially funded by the Project FIRST (ForecastIng eRuptive activity at Stromboli volcano: Timing, eruptive style, size, intensity, and duration), INGV-Progetto Strategico Dipartimento Vulcani 2019 (Delibera n. 144/2020). This is contribution no. 637 of the ClerVolc program of the International Research Center for Disaster Sciences and Sustainable Development of the University of Clermont Auvergne.
    Beschreibung: Published
    Beschreibung: 50
    Beschreibung: OSV1: Verso la previsione dei fenomeni vulcanici pericolosi
    Beschreibung: JCR Journal
    Schlagwort(e): Stromboli volcano ; flank eruptions ; Lava flows
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Publikationsdatum: 2024-04-24
    Beschreibung: Groundwater is a vital resource for humans, non-human species, and ecosystems. It has allowed the development of human evolution and civilizations throughout history (e.g., Wittfogel 1956, Tempelhoff et al. 2009, Cuthbert and Ashley 2014, Roberts 2014). However, it faces multiple potential threats that make it vulnerable and fragile. Climate change and human activities are the primary causes that have led to water cycle disruptions, particularly a decline in groundwater quality and quantity (e.g., Gleeson et al. 2020, Chaminé et al. 2022, Richardson et al. 2023). Climate variability has induced droughts, floods, and other extreme weather conditions, significantly impacting groundwater in many regions. Meanwhile, human activities such as over-abstraction, ground contamination, deforestation, land-use change, and other anthropogenic pressures have further compromised groundwater status. Nonetheless, groundwater continues to fulfill water demands in many regions or during specific periods. Therefore, concerted efforts are imperative to ensure its sustainability. So, conservation practices and nature-based solutions must be adopted to efficiently manage groundwater and shield it from additional potential hazards or risks (e.g., contamination, pollution, or over-abstraction). Failure to act quickly can result in the loss of this critical resource, with severe consequences for the economy, society, and ecosystems. From this perspective, it is imperative to prioritize actions underscored by technical-scientific integrity, environmental responsibility, societal sensitivity, and ethical practices.
    Beschreibung: Published
    Beschreibung: 97
    Beschreibung: OS: Terza missione
    Beschreibung: OSA5: Energia e georisorse
    Beschreibung: JCR Journal
    Schlagwort(e): groundwater ; resource management ; sustainability ; hydrogeoethics ; geoethics ; societal well-being ; 05.03. Educational, History of Science, Public Issues ; 03.02. Hydrology ; 04.04. Geology ; 05.09. Miscellaneous
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    facet.materialart.
    Unbekannt
    Springer
    In:  EPIC3Springer, 24 p., pp. 281-304, ISBN: 9783031455537
    Publikationsdatum: 2024-01-08
    Beschreibung: Calving of iceberg at ice shelves and floating glacier tongues is a poorly understood process, hence a physically motivated calving law is not yet existing. The demands on developing appropriate models for calving is large, as calving rates are needed for large scale ice sheet models that simulate the evolution of ice sheets. Here, we present a new approach for simulating fracture in ice. Our model is based on a finite strain theory for a viscoelastic Maxwell material, as the large simulation time leads to high strains. The fracturing process is simulated using a fracture phase field model that takes into account the elastic strain energy. We conduct simulations for a typical calving front geometry, with ice rises governing the formation of cracks. To represent the stress state adequately, we first conduct a spin-up to allow the viscous contribution to develop before the fracture phase field is computed. The analysis comprises the assessment of the crack path in comparison to observations, the influence of the spin-up, as well as elastic versus viscous strain contributions based on Hencky strain. Additionally, an estimate of released energy based on high resolution optical imagery of a Greenlandic calving front is presented.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Inbook , peerRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Publikationsdatum: 2024-03-12
    Beschreibung: We have provided the first estimate of scat- tering and intrinsic attenuation for the Gargano Prom- ontory (Southern Italy) analyzing 190 local earthquakes with M L ranging from 1.0 to 2.8. To separate the intrin- sic Q i and scattering Q s quality factors with the Wen- nerberg approach (1993), we have measured the direct S waves and coda quality factors ( Q 𝛽 , Q c ) in the same volume of crust. Q 𝛽 parameter is derived with the coda normalization method (Aki 1980) and Q c factor is derived with the coda envelope decay method (Sato 1977). We selected the coda envelope by performing an automatic picking procedure from T start = 1.5T S up to 30 s after origin time (lapse time T L ). All the obtained quality factors clearly increase with frequency. The Q c values correspond to those recently obtained for the area. The estimated Q i are comparable to the Q c at all frequencies and range between 100 and 1000. The Q s parameter shows higher values than Q i , except for 8 Hz, where the two estimates are closer. This implies a pre- dominance of intrinsic attenuation over the scattering attenuation. Furthermore, the similarity between Q i and Q c allows us to interpret the high Q c anomaly previ- ously found in the northern Gargano Promontory up to a depth of 24 km, as a volume of crust characterized by very low seismic dumping produced by conversion of seismic energy into heat. Moreover, most of the earth- quake foci fall in high Q i areas, indicating lower level of anelastic dumping and a brittle behavior of rocks.
    Beschreibung: Published
    Beschreibung: 827-846
    Beschreibung: OST1 Alla ricerca dei Motori Geodinamici
    Beschreibung: JCR Journal
    Schlagwort(e): Seismic attenuation · Coda normalization method · Intrinsic quality factor · Scattering quality factor · Southern Italy · Gargano Promontory · OTRIONS seismic network ; 04.06. Seismology
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Publikationsdatum: 2024-05-16
    Beschreibung: This review summarizes what the volcanology community has learned thus far from studying the deposits of pyroclastic currents (PCs) from the 1980 eruption sequence at Mount St. Helens. The review includes mass flow events during the May 18 eruption, including the lateral blast, the afternoon column collapse and boil-over PC activity, and some aspects of the debris avalanche. We also include a summary of PCs generated in the smaller eruptions following the climactic May 18 event. Our objective is to summarize the state of our understanding of PC transport and emplacement mechanisms from the combination of field and laboratory observations, granular flow experiments, and numerical modeling techniques. Specifically, we couple deposit characteristics, experiments, and numerical modeling techniques to critically address the problems of (1) constraining conditions in the flow boundary zone at the time of deposition; (2) the influence of substrate roughness and topography on PC behavior; (3) the prevalence, causes, and consequences of substrate erosion by PCs; and (4) the reconstruction of PC transportation and sedimentation processes from a combination of geophysical and sedimentological observations. We conclude by providing opportunities for future research as our field, experimental, and numerical research techniques advance.
    Beschreibung: Published
    Beschreibung: 24
    Beschreibung: OSV2: Complessità dei processi vulcanici: approcci multidisciplinari e multiparametrici
    Beschreibung: JCR Journal
    Schlagwort(e): numerical modeling, mount St. Helens, physical volcanology ; 04.08. Volcanology
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Publikationsdatum: 2024-06-13
    Beschreibung: The ability to predict the mobility of rock avalanches is necessary when designing strategies to mitigate the risks they pose. A popular mobility indicator of the flow front is the Heim’s apparent friction coefficient muH. In the field, muH shows a decrease in value as flow volume V increases. But this correlation has been a mystery as to whether it is due to a causal relationship between V and mobility since: (1) field data of muH do not collapse onto a single curve because typically widely scattered and (2) laboratory experiments have shown an opposite volume effect on the center of mass mobility of miniature flows. My numerical simulations confirm for the first time the existence of a functional relationship of scaling parameters where muH decreases as V increases in unsteady and nonuniform 3D flows. Data scatter is caused by muH that is affected by numerous other variables besides V. The interplay of these variables produces different granular regimes with opposite volume effects. In particular, muH decreases as V increases in the regime characterized by a relatively rough subsurface. The relationship holds for large-scale flows that, like rock avalanches, consist of a very large number of fine clasts traveling in wide channels. In these dense flows, flow front mobility increases as flow volume increases, as channel width increases, as grain size decreases, as basal friction decreases and as flow scale increases. Larger-scale flows are more mobile because they have larger Froude number values.
    Beschreibung: Published
    Beschreibung: 933–947
    Beschreibung: OSV1: Verso la previsione dei fenomeni vulcanici pericolosi
    Beschreibung: JCR Journal
    Schlagwort(e): Pyroclastic Flows ; Rock Avalanches ; Flow Front ; Mobility
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Publikationsdatum: 2024-05-27
    Beschreibung: Invasive alien species represent one of the main environmental threats to native biodiversity and can also strongly alter the biogeochemical cycles within an ecosystem. This study aims to define the distribution of the invasive alien species Cotula cor-onopifolia L. within the protected wetland "Variconi" (Campania region, southern Italy) and evaluate the potential role of water geochemical features as interpretation tools for pattern distribution. The presence of C. coronopifolia was assessed in the field, and a distribution map was drawn; concomitantly thirty-nine water samples were collected from groundwater and surface water bodies for chemical analyses. The results showed that C. coronopifolia preferentially colonized the sector of the wetland characterized by high halinity, while it is totally absent in retrodunal and sandy coastal area with very high halinity. The cartography presented can be used as a tool to help target future management interventions. Through our multidisciplinary approach, new evidence has been provided on the ecology of this invasive alien plant that occupies several wetlands worldwide. The replicability of this method may be useful to assess the level of invasion of an alien species but also to predict its evolution as a function of environmental parameters.
    Beschreibung: Published
    Beschreibung: 1653–1668
    Beschreibung: JCR Journal
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
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  • 11
    Publikationsdatum: 2024-05-27
    Beschreibung: Active volcanoes show many mild thermal anomalies, because the ground surface is sensible to changes in the advective processes, occurring through the network of fissures. This data report shows the temperatures, recorded from January 2020 to February 2023, by a remote-controlled monitoring station. The VCS station is located on the summit of La Fossa cone (Vulcano, Aeolian Islands), in a zone of intense diffuse degassing. The temperature data, hourly registered at VCS, are available in the supplementary Excel file. The thermal data are part of the comprehensive network, performed by the Istituto Nazionale di Geofisica e Vulcanologia, for volcanic surveillance. On the Island of Vulcano, the active volcanic system under la Fossa caldera has been affected by multiple exhaling crises, interpreted as unrest of volcanic activity. The temperature time series provided reference data showing the thermal transition of the volcanic ground surface from a background degassing condition, through unrest, to the new thermal condition that followed the unrest period.
    Beschreibung: OvFu 0304.010 - Italian Presidenza del Consiglio dei Ministri—Dipartimento della Protezione Civile
    Beschreibung: Published
    Beschreibung: 40
    Beschreibung: OSV2: Complessità dei processi vulcanici: approcci multidisciplinari e multiparametrici
    Beschreibung: JCR Journal
    Schlagwort(e): heat flux ; time series ; Unrest ; Vulcano ; diffuse degassing ; thermal monitoring
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Erwartet Verfügbarkeit
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  • 12
    facet.materialart.
    Unbekannt
    Springer
    Publikationsdatum: 2024-06-28
    Beschreibung: Earth System Literacy offers a rich matrix of narratives about (planet) Earth, World and Humans when interwoven with cultural artefacts (e.g. arts, history). Anthropogenic global change locks them together in a unifying framework. By making a distinction between reproduction, work (ergon, Greek) and civicness, there are narratives that convey what characterises the human condition today, including the material, social and historic settings of the Anthropocene.
    Beschreibung: Published
    Beschreibung: 445–449
    Schlagwort(e): Anthropocene ; Earth System Literacy ; Narratives ; 05.03. Educational, History of Science, Public Issues
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: book chapter
    Standort Signatur Erwartet Verfügbarkeit
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  • 13
    Publikationsdatum: 2024-07-09
    Beschreibung: Published
    Beschreibung: OS: Terza missione
    Schlagwort(e): 04.08. Volcanology
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: book
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  • 14
    Publikationsdatum: 2020-02-12
    Schlagwort(e): 550 - Earth sciences
    Materialart: info:eu-repo/semantics/book
    Standort Signatur Erwartet Verfügbarkeit
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  • 15
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 137-144 
    ISSN: 1476-5535
    Schlagwort(e): Composting ; Explosives ; Propellants ; Thermophilic ; Mesophilic ; Bioremediation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Composting was investigated as a bioremediation technology for clean-up of sediments contaminated with explosives and propellants. Two field demonstrations were conducted, the first using 2,4,6-trinitrotoluene (TNT), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetraazocine (HMX), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), and N-methyl-N,2,4,6-tetranitroaniline (tetryl) contaminated sediment, and the second using nitrocellulose (NC) contaminated soil. Tests were conducted in thermophilic and mesophilic aerated static piles. Extractable TNT was reduced from 11840 mg/kg to 3 mg/kg, and NC from 13090 mg/kg to 16 mg/kg under thermophilic conditions. Under mesophilic conditions, TNT was reduced from 11 190 mg/kg to 50 mg/kg. The thermophilic and mesophilic half-lives were 11.9 and 21.9 days for TNT, 17.3 and 30.1 days for RDX, and 22.8 and 42.0 days for HMX, respectively. Known nitroaromatic transformation products increased in concentration over the first several weeks of the test period, but decreased to low concentrations thereafter.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 16
    ISSN: 1476-5535
    Schlagwort(e): Fructo-oligosaccharide ; 1-Kestose ; Glycoprotein ; Fructosyl-transferring activity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Two extracellular β-fructofuranosidases (E-1 andE-2) fromAureobasidium sp. ATCC 20524, producing 1-kestose (1F-β-fructofuranosyl-sucrose) from sucrose, were purified to homogeneity. Molecular weights of the enzymes were estimated to be about 304000 (E-1) and 315000 (E-2) Da by gel filtration. The enzymes contained 33% (w/w) (E-1) and 27% (w/w) (E-2) carbohydrate. TheK m values for sucrose ofE-1 andE-2 andE-2 were 0.34 and 0.28 M, respectively. were 0.34 and 0.28 M, respectively. The enzymatic profiles of these enzymes were almost identical to intracellular enzymesP-1 andP-2 except for the differences in carbohydrate content andK m values ofE-2 andP-2.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 17
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 149-161 
    ISSN: 1476-5535
    Schlagwort(e): Toxin ; Secondary plant metabolite ; Allelochemical ; Insecticide ; Mycotoxin ; Endocytobiont
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Many species of insects cultivate, inoculate, or contain symbiotic fungi. Insects feed on plant materials that contain plant-produced defensive toxins, or are exposed to insecticides or other pesticides when they become economically important pests. Therefore, it is likely that the symbiotic fungi are also exposed to these toxins and may actually contribute to detoxification of these compounds. Fungi associated with bark beetles, ambrosia beetles, termites, leaf-cutting ants, long-horned beetles, wood wasps, and drug store beetles can variously metabolize/detoxify tannins, lignins, terpenes, esters, chlorinated hydrocarbons, and other toxins. The fungi (Attamyces) cultivated by the ants and the yeast (Symbiotaphrina) contained in the cigarette beetle gut appear to have broad-spectrum detoxifying abilities. The present limiting factor for using many of these fungi for large scale detoxification of, for example, contaminated soils or agricultural commodities is their slow growth rate, but conventional strain selection techniques or biotechnological approaches should overcome this problem.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 18
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 163-172 
    ISSN: 1476-5535
    Schlagwort(e): Biosensors ; Process control ; Enzyme thermistor ; Immunoassay ; Bio-field effect transistor
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary A short review about the biosensor research activities for bioprocess monitoring in the F.R.G. after its reunification is given. The principles of biosensor applications are presented. In situ sensors and sensors based on the principles of flow injection analysis are studied. Some applications of a four-channel enzyme thermistor, bio-field effect transistors, and immunoanalysis systems for real process monitoring are presented.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 19
    ISSN: 1476-5535
    Schlagwort(e): Vibrio vulnificus ; Oyster ; Monoclonal antibody ; Most probable number ; Enzyme immunoassay
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Oysters, suspended particulate matter (SPM), sediment and seawater samples were collected from West Galveston Bay, Texas over a 16-month period and analyzed for the presence ofVibrio vulnificus, a naturally-occurring human marine pathogen. Detection and enumeration ofV. vulnificus was performed using a species-specific monoclonal antibody (mAb FRBT37) in an enzyme immunoassay (EIA)-most probable number (MPN) procedure capable of detecting as few as 2000 target organisms.V. vulnificus was not detected in seawater, oyster or SPM samples during the cold weather months, but was detected at low levels in several sediment samples during this time period. Increased levels of the organism were first observed in early spring in the sediment, and then in SPM and oysters. The major increase inV. vulnificus occurred only after the seawater temperature had increased above 20°C and the winter-spring rainfall had lowered the salinity below 16‰. The highestV. vulnificus levels at each site were associated with suspended particulate matter. These results are consistent with the hypothesis that (1)V. vulnificus over-winters in a floc zone present at the sediment-water interface, (2) is resuspended into the water column in early spring following changes in climatic conditions, (3) colonizes the surfaces of zooplankton which are also blooming during early spring and (4) are ingested by oysters during their normal feeding process.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 20
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 235-238 
    ISSN: 1476-5535
    Schlagwort(e): Biodegradation ; Pseudomonas putida ; Immobilization ; Sodium cyanide
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Pseudomonas putida, isolated from contaminated industrial wastewaters and soil sites, was found to utilize sodium cyanide (NaCN) as a sole source of carbon and nitrogen. Cells, immobilized in calcium alginate beads (1–2 mm diameter) were aerated in air-uplift-type fluidized batch bioreactor containing 100–400 ppm of NaCN. Degradation of NaCN was monitored for 168 h by analyzing gaseous and dissolved ammonia (NH3), CO2, pH and optical density. The results indicated that the alginate-immobilized cells ofP. putida were able to degrade NaCN into NH3 and CO2 in a time-dependent manner.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 21
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 229-234 
    ISSN: 1476-5535
    Schlagwort(e): Heat shock protein (HSP) ; Yeast ; Saccharomyces ; Viability ; Thermotolerance ; Ethanol tolerance
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Heat shock and ethanol stress of brewing yeast strains resulted in the induction of a set of proteins referred to as heat shock proteins (HSPs). At least six strongly induced HSPs were identified in a lager brewing strain and four HSPs in an ale brewing strain. Four of these HSPs with molecular masses of approximately 70, 38, 26 and 23 kDa were also identified in two laboratory strains ofSaccharomyces cerevisiae. The appearance of HSPs correlated with increased survival of strains at elevated temperatures and high concentrations of ethanol. These results suggest that HSPs may play a role in the ethanol and thermotolerance of yeasts. The properties of these proteins and membrane fatty acids in relation to heat and ethanol shock are being investigated.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 22
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 239-245 
    ISSN: 1476-5535
    Schlagwort(e): Novel polysaccharide ; Bacillus licheniformis ; Raffia venifera ; d-Glucose ; d-Mannose ; d-Xylose
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary A polysaccharide producing strain ofBacillus licheniformis was isolated from exudate of raffia palm,Raffia vinifera. The optimum conditions for growth and polysaccharide production have been investigated and established. No appreciable polysaccharide was formed on glucose. It grew best in Czapek-Dox media with sucrose as the carbon source. The polysaccharide has been characterized as a heteropolymer containingd-glucose,d-mannose andd-xylose.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 23
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 269-269 
    ISSN: 1476-5535
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 24
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 251-255 
    ISSN: 1476-5535
    Schlagwort(e): β-Fructofuranosidase ; Deglycosylation ; Aureobasidium ; Enzymatic stability
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Most of the carbohydrate moiety of β-fructofuranosidaseP-1 fromAureobasidium sp. ATCC 20524 was removed by endo-β-N-acetylglucosaminidase F. A subunit of 94000 Da was observed in SDS-PAGE after deglycosylation. TheK m value for sucrose was not changed by deglycosylation but the stability at pH 4–5 and 50°C was decreased. The deglycosylated enzyme was more sensitive to proteases such as pronase E and subtilisin than the native enzyme. It is considered that the carbohydrate moiety of β-fructofuranosidaseP-1 contributes to the stability of the enzyme but is not essential in its catalytic function.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 25
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 153-197 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract It is suggested that a system of chemical substances, called morphogens, reacting together and diffusing through a tissue, is adequate to account for the main phenomena of morphogenesis. Such a system, although it may originally be quite homogeneous, may later develop a pattern or structure due to an instability of the homogeneous equilibrium, which is triggered off by random disturbances. Such reaction-diffusion systems are considered in some detail in the case of an isolated ring of cells, a mathematically convenient, though biologically unusual system. The investigation is chiefly concerned with the onset of instability. It is found that there are six essentially different forms which this may take. In the most interesting form stationary waves appear on the ring. It is suggested that this might account, for instance, for the tentacle patterns onHydra and for whorled leaves. A system of reactions and diffusion on a sphere is also considered. Such a system appears to account for gastrulation. Another reaction system in two dimensions gives rise to patterns reminiscent of dappling. It is also suggested that stationary waves in two dimensions could account for the phenomena of phyllotaxis. The purpose of this paper is to discuss a possible mechanism by which the genes of a zygote may determine the anatomical structure of the resulting organism. The theory does not make any new hypotheses; it merely suggests that certain well-known physical laws are sufficient to account for many of the facts. The full understanding of the paper requires a good knowledge of mathematics, some biology, and some elementary chemistry. Since readers cannot be expected to be experts in all of these subjects, a number of elementary facts are explained, which can be found in text-books, but whose omission would make the paper difficult reading.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 26
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 319-334 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 27
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 335-337 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 28
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. I 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 29
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 335-348 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract The classical metaphor of the genetic program written in the DNA nucleotidic sequences is reconsidered. Recent works on algorithmic complexity and logical properties of computer programs and data are used to question the explanatory value of that metaphor. Structural properties of strings are looked for which would be necessary to apply to DNA sequences if the metaphor is to be taken literally. The notion of sophistication is used to quantify meaningful complexity and to distinguish it from classical computational complexity. In this context, the distinction between program and data becomes relevant and an alternative metaphor of DNA as data to a parallel computing network embedded in the global geometrical and biochemical structure of the cell is discussed. An intermediate picture of an evolving network emerges as the most likely where the output of the cellular computing network can produce, at a different time scale, changes in the structure of the network itself by means of changes in the DNA activity patterns.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 30
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 349-358 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract When two strings of symbols are aligned it is important to know whether the observed number of matches is better than that expected between two independent sequences with the same frequency of symbols. When strings are of different lengths, nulls need to be inserted in order to align the sequences. One approach is to use simple approximations of sampling for replacement. We describe an algorithm for exactly determining the frequencies of given numbers of matches, sampling without replacement. This does not lead to a simple closed form expression. However we show examples where sampling with, or without, replacement give very similar results and the simple approach may be adequate for all but the smallest cases.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 31
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 509-525 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Pairwise optimal alignments between three or more sequences are not necessarily consistent as a whole, but consistent and inconsistent residues are usually distributed in clusters. An efficient method has been developed for locating consistent regions when each pairwise alignment is given in the form of a “skeletal representation” (Bull. math. Biol. 52, 359–373). This method is further extended so that the combination of pairwise alignments that gives the greatest consistency is found when possibly many alignments are equally optimal for each pairwise comparison. A method for acceleration of simultaneous multiple sequence alignment is proposed in which consistent regions serve as “anchor points” limiting application of direct multi-way alignment to the rest of “inconsistent” regions.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 32
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 527-534 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Sufficient conditions are given for the unlimited growth or otherwise in multitype population size dependent Galton-Watson processes. These conditions are given in terms of moments of offspring distributions and extend known conditions for processes with one type.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 33
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 535-547 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract The variability of the duration of the cell cycle is explained by the phenomenon of sensitive dependence upon initial conditions; as may occur in deterministic non-linear systems. Chaotic dynamics of a system is the result of this sensitive dependence. First a deterministic system is formulated that is equivalent to the Smith-Martin transition probability model of the cell cycle. Next the model is extended to a dynamic process that ranges over the cell generations. A deterministic non-linear relationship between the cycle time of the mother and daughter cell is established. It clarifies the variability of mother-daughter correlation for the different cell types. The model is fitted to two different cell cultures; it shows that the graph of the non-linear relation has the same shape for different cell types.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 34
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 583-596 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 35
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. I 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 36
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 549-582 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Recently a mathematical model of the prevascular phases of tumor growth by diffusion has been investigated (S. A. Maggelakis and J. A. Adam,Math. Comput. Modeling, in press). In this paper we examine in detail the results and implications of that mathematical model, particularly in the light of recent experimental work carried out on multicellular spheroids. The overall growth characteristics are determined in the present model by four parameters:Q, γ, b, andδ, which depend on information about inhibitor production rates, oxygen consumption rates, volume loss and cell proliferation rates, and measures of the degree of non-uniformity of the various diffusion processes that take place. The integro-differential growth equation is solved for the outer spheroid radiusR 0(t) and three related inner radii subject to the solution of the governing time-independent diffusion equations (under conditions of diffusive equilibrium) and the appropriate boundary conditions. Hopefully, future experimental work will enable reasonable bounds to be placed on parameter values referred to in this model: meanwhile, specific experimentally-provided initial data can be used to predict subsequent growth characteristics ofin vitro multicellular spheroids. This will be one objective of future studies.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 37
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Workers of the speciesLeptothorax acervorum show age-polyethism, they start their life as broodworkers and later on they become nestworkers and foragers. Nestworkers and foragers of this ant species are inactive for 72% and 15% of the total time respectively. The short bursts of activity within the nest do not occur randomly but are synchronized so that the whole nest population exhibits nonperiodic pulses of activity: the ants were seen to wake each other actively. In addition starvation experiments were done to assess whether ants react upon food availability. In appeared that during a longlasting period of starvation the proportion of active ants in the nest is at a higher approximately constant level.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 38
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 1-20 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract An organism persists only if it satisfies internal and external constraints. Within the organism networks of processes meet the constraints. In such networks a principle of matching often obtains: the pattern of coupling among processes matches the correlation among constraints. That is, a module—a cluster of coupled processes—meets a constraint. Dissociable modules meet dissociàble constraints. A hierarchy of modules meets a hierarchy of constraints. We have inquired whether such matching is predicted by an optimality criterion in a simple example. We find that in an ensemble of networks with unreliable processes, the networks that meet the constraints with highest reliability obey the principle of matching. The difference in reliability between modular and nonmodular networks that meet the same constraints is a function of the probability of success per process. Our results suggest that this difference is maximal at a probability of success that increases monotonically with the number of processes in the network.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 39
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 59-75 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract A method is described for estimating the distribution and hence testing the statistical significance of sequence similarity scores obtained during a data-bank search. Maximum-likelihood is used to fit a model to the scores, avoiding any costly simulation of random sequences. The method is applied in detail to the Smith-Waterman algorithm when gaps are allowed, and is shown to give results very similar to those obtained by simulation.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 40
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 401-412 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract We develop a theory for host seeking decisions in mosquitoes that explicitly considers the tradeoffs mosquitoes face in allocation to somatic and gametic function. Specifically, we consider conditions under which mosquitoes should seek out nectar and blood hosts upon encountering host odours. Results from development of a dynamic model that considers free and crop energy states suggest that mosquitoes should seek out blood hosts under a wide variety of conditions but that decisions to seek nectar depends upon crop volume, concentration and free energy. This pattern arises because mosquitoes carrying large crop loads are constrained in their ability to obtain large blood meals due to space limitations in the abdomen. The predicted patterns of behaviour are supported by published observations of mosquito behaviour.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 41
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 413-422 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract In behavioral ecology, diet selection is often predicted by using a theory in which it is assumed that behaviors have evolved to maximize the rate of intake of energy. In this theory, it is assumed that fitness is a monotonic function of energy intake. An alternative is to deal directly with fitness, measured in terms of expected reproduction, and thus connect short term behavior with reproduction. Following the usual assumptions of the theory of diet choice, fitness satisfies a partial differential-difference equation. Conditions under which rate maximizing and state variable theories of diet selection yield identical predictions are identified. When predation, as well as starvation, is a source of mortality, the identification is not as complete.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 42
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 445-464 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Environmental uncertainty can be both a cause and consequence of chance variation in many of the phenotypic factors associated with the control of clutch size in birds. When such uncertainty inflates or otherwise influences the variance associated with expected reproductive success for any genotype, it will also influence the resulting phenotypic optima. Random variation that affects the evolution of clutch size optima explicitly may occur both within (intra-) and across (inter-) generations. Examples of intra-generational uncertainty could include chance variation in: (1) the quality and quantity of offspring, (2) parental quality, and (3) temporal resources like food. Inter-generational uncertainty would include chance variation in demographic and population characters. With respect to clutch (or litter) size, almost all forms of uncertainty tend to favor an optimum (genetic) strategy with a clutch that is smaller than the clutch associated with the apparent or actual maximal fitness of an individual parent. The overall effect of all the components of uncertainty can be evaluated through the integration of all this phenotypic variation: however each step of the integration is a conditional expectation of each component. Therefore, a single factor analysis may indicate a false optimum, and an integrated analysis of all components is necessary to evaluate the importance of their individual and joint effects on the adaptive evolution of clutch size.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 43
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 503-519 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract A difference equation model for the dynamics of a semelparous size-structured species consisting of juvenile and adult individuals is derived and studied. The adult population consists of two size classes, a smaller class and a larger more fertile class. Negative feedback occurs through slowed juvenile growth due to increased total population levels during the developmental period and consequently a smaller adult size at maturation. Intra-specific competition coefficients are size dependent and measure the strength of intra-specific competition between juveniles and adults. It is shown that equilibrium states in which adults and juveniles occur together at all times are in general destabilized by significantly increased juvenilevs adults competition with the result that stable periodic cycles appear, in which the generations alternate in time and hence avoid competition. This result supports the tenet that intra-specific competition between juveniles and adults is destabilizing. Exceptions to this destabilization principle are found, however, in which populations exhibiting non-equilibrium, aperiodic dynamics can be equilibrated by increase competition between juveniles and adults. This occurs, for example, when adult fertility and competition coefficients are significantly size class dependent.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 44
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 537-561 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract An epithelial cell is modeled as a single compartment, bounded by apical and basolateral cell membranes, and containing two nonelectrolyte solute species, nominally NaCl and KCl. Membrane transport of these species may be metabolically driven, or it may follow the transmembrane concentration gradients, either singly (a channel) or jointly (a cotransporter). To represent the effect of stretch-activated channels or shrinkage-activated cotransporters, the membrane permeabilities and cotransport coefficients are permitted to be functions of cell volume. When this epithelium is considered as a dynamical system, conditions are indicated which guarantee the uniqueness and stability of equilibria. Experimentally, many epithelial cells can regulate their volume, and such volume regulatory capability is defined for this model. It is clearly distinct from dynamical stability of the equilibrium and requires more stringent conditions on the volume-dependent permeabilities and cotransporters. For a previously developed model of the toad urinary bladder (Strieteret al., 1990,J. gen. Physiol. 96, 319–344) the uniqueness and stability of its equilibria are indicated. The analysis also demonstrates that under some conditions a second stable equilibrium may appear, along with a saddle-node bifurcation. This is illustrated numerically in a modified model of the epithelium of the thick ascending limb of Henle.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 45
    Digitale Medien
    Digitale Medien
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    Bulletin of mathematical biology 54 (1992), S. 687-694 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 46
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 54 (1992), S. 649-672 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Models of the dynamical interactions important in generating immune reactivity have generally assumed that the immune system is a single well-stirred compartment. Here we explicitly take into account the compartmentalized nature of the immune system and show that qualitative conclusions, such as the stability of the immune steady state, depend on architectural details. We examine a simple model idiotypic network involving only two types of B cells and antibody molecules. We show, for model parameters used by De Boeret al. (1990,Chem. Eng. Sci. 45, 2375–2382), that the immune steady state is unstable in a one compartmental model but stable in a two compartment model that contains both a lymphoid organ, such as the spleen, and the circulatory system.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 47
    Digitale Medien
    Digitale Medien
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    Bulletin of mathematical biology 54 (1992), S. 839-873 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Using the chromium release assay and the single cell assay in agarose, we study the cytotoxic reaction of the MHC-restricted T lymphocyte clones P89:15 and P1:3, which recognize distinct but specific tumour antigens on the surface of syngeneic P815 mastocytoma cells. We propose a mathematical model which describes these experiments, accounts for the strongly non-Michaelian behaviour of the reaction and permits us to estimate the kinetic parameters characterizing effector-target conjugation and lethal hit delivery. The results show that the binding and lytic activity of effector cells is modulated by the number of targets bound to them. The binding of a second target by an effector having already a target bound is facilitated; on the other hand, an effector having bound two targets delivers a lethal hit more slowly than one with a single target bound. We investigate the role of these kinetic properties in the competition between the process of tumour progression due to cancer cell replication and the process of tumour regression due to T lymphocyte cytotoxic activity. For both clones, we estimate the effector-target ratio beyond which rejection prevails. This ratio is nine times larger for P1:3 than for P89:15. Furthermore, our analysis suggests that there exists an optimal specificity minimizing this ratio. Deviations from this optimum, be it in the sense of an increase or decrease of specificity, tendsto stabilize the tumoural state: a situation which in the broader context of the immune response evolution and regulation can be viewed as animmune response dilemma.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 48
    Digitale Medien
    Digitale Medien
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    Bulletin of mathematical biology 54 (1992), S. 929-938 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract In this paper a stochastic model for a two-compartment system which incorporates Erlang residence time distributions (i.e. the residence times have the gamma distribution where the shape parameters assume integer values only) into each compartment is generalized to include random rate coefficients. Analytical forms of the model are derived for the case where the rate coefficients have gamma densities. A relationship is established between the new models and existing models that are in current practical usage.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 49
    Digitale Medien
    Digitale Medien
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    Bulletin of mathematical biology 54 (1992), S. 939-955 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Oscillations and chaos can be modelled and observed in a realistic simulation model of interacting prey-predator populations based on Monte Carlo simulation methods. These nonlinear phenomena are linked with some biological and physical bifurcation parameters and mathematical tools from dynamical systems theory may be used in order to characterize this behaviour. Chaotic dynamics are therefore, in our simulation, more the rule than the exception, and are related to delays associated with spatial degrees of freedom.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 50
    Digitale Medien
    Digitale Medien
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    Bulletin of mathematical biology 54 (1992), S. 1023-1038 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Cells displaying the classic multidrug resistant (MDR) phenotype possess a transmembrane protein (p170 or P-glycoprotein) which can actively extrude cytotoxic agents from the cytoplasm. A mathematical model of this drug efflux pump has been developed. Outward transport is modeled as a facilitated diffusion process. Since energy-dependent efflux of cytotoxic agents requires that ATP also bind to p170, the model includes a dynamic calculation for efflux rate which considers Michaelis-Menten kinetics for both the substrate agent and ATP. The final system consists of one partial differential equation (PDE) for the facilitated diffusion of substrate agents out of the cell a 2×2 ordinary differential equation (ODE) system for the dynamic calculation of the ATP-ADP pool, and a dynamic algebraic calculation of the efflux rate given substrate levels at the interior cell membrane interface and ATP levels in the cell. A stability analysis of the ATP-ADP pool distribution and a simplistic closed form solution of the linearized PDE are included. Numerical simulations are also provided.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 51
    Digitale Medien
    Digitale Medien
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    Bulletin of mathematical biology 54 (1992), S. 1039-1056 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Reentry in the heart is the repeated excitation of the same tissue by a single excitation wave; it is responsible for several types of cardiac arrhythmia. The simplest model which permits the phenomenon of reentry is two laterally coupled excitable fibers; in this paper we examine such a model in order to establish a basis for the understanding of the fundamental physical processes underlying the process of reentry. Two versions of the FitzHugh-Nagumo equations are used to develop complementary numerical and analytical results for the coupled fiber model. On the basis of numerical studies, regions of qualitatively different behaviour are mapped in the parameter space of excitation threshold and coupling strength between the fibers, and the effect of the rate of recovery is explored. Some of these regions are also obtained analytically, in good agreement with the numerical results. Finally, the results are discussed in the light of recent work on the role of the anisotropy of cardiac tissue in the initiation of reentrant activity in the heart.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 52
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    Digitale Medien
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    Bulletin of mathematical biology 54 (1992), S. 1069-1081 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract A sigmoid curve with three fitting parameters is proposed as a descriptive model for the spatial velocity field in one-dimensional growth of plant organs. Analytic expressions are derived for the relative elemental growth (REG) rate, the position and value of the REG rate maximum, the length of the growth zone, the inverse of the growth trajectory and cell length in the “elongation only” zone. The expressions are fit to published data to characterize the effects of environmental variation on growth of monocotyledonous roots. The simple expressions for growth may prove useful in mechanistic models. The fitted curves summarize more than a decade of observations and thus provide a challenge to theorists.
    Materialart: Digitale Medien
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  • 53
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 115-136 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract By considering all orderings of the input samples, which are discrete-time continuous-valued, it is shown here that a weighted median (WM) filter of spanN can be specified unambiguously by 2N−1 consistent linear inequalities relating the weights. This specification is identical to that of a self-dual threshold function with the same weights. It is also shown that WM filters with symmetric weights can be specified by ternary threshold functions. Based on these inequalities, properties of WM filters which can be used to check equivalence of some WM filters are derived.
    Materialart: Digitale Medien
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  • 54
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 137-151 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract Because binary mathematical morphology permits fast local neighborhood operations by flash conversion, it is used extensively in high-speed pattern-recognition computer systems. Further, since anyN-dimensional integer function may be represented by an (N + 1)-dimensional binary (bilevel) function, ordinary two-dimensional graylevel images become three-dimensional binary images. Thus these images may be processed by high-speed flash-conversion computers assuming that a sufficiently compact three-dimensional kernel can be devised. The tetradekahedron of the face-centered-cubic tessellation forms a perfect kernel in three-dimensions. Its neighborhood is compact. It has total symmetry with all 12 neighbors equidistant from the central element. Using this kernel a variety of useful three-dimensional morphological operations may be performed for target track detection, shaded graphics, data clustering, automated focusing, and spatial filtering.
    Materialart: Digitale Medien
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  • 55
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 153-169 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract Two techniques for image restoration are compared in this paper. One is a technique based on the theory of optimal adaptive stack filtering; the other is a recently developed vector detection approach to image restoration. The primary difference between these two techniques is that the optimal detection technique exploits multilevela priori information, while the stack filter uses only single level zero crossing information. The design constraints for stack filters and vector detection are similar. Both approaches rely on the existence of a training sequence for the image source in order to obtain optimal processing. Adaptive stack filters do, however, require a training set of the noise while the optimal detection approach only needs a multivariate parametric representation. The image-restoration performance of these two methods is compared in a signal dependent noise environment characterizing imaging systems with speckle, film-grain, and Poisson shot noise. Comparisons are made using the mean absolute error measure as well as a subjective measure.
    Materialart: Digitale Medien
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  • 56
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 325-352 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract The stability of digital ladder filters close in form, via the lossless discrete integrator (LDI) transformation, to doubly terminatedLC Cauer ladder low-pass filters is studied. The LDI transformation does not necessarily map stable analogue into stable digital filters. Necessary and sufficient conditions for these digital filter to be lossless and for a corresponding doubly terminated filter to be stable are given. LDIs are often used in the design of switched capacitor (SC) filters. For this case we provide a threshold sampling rate above which the SC LDI filter retains the stability of the analogue filter. In spite of the stability problem with the LDI mapping, it has been observed that when applied to simulate analogue filters the resulting filter is stable. It can now be argued that, in these cases, other factors in the determination of the sampling rate leads typically to a choice that is also sufficiently above the threshold rate for stability. The theory described is also useful to derive more general digital filters and to perform the design of stable LDI filters exclusively in the Z-plane without reference to analogue prototypes.
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  • 57
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 285-307 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract In this paper we describe a family of operators for constructing nontrivial left and right coprime factorizations under rather weak conditions for a large class of nonlinear feedback control systems that has a stabilizable or unstabilizable plant, using a common criterion of input-output stability. The proposed sufficiency and construction method are based on a generalization of the nonlinear Lipschitz operator theory formulated by us for such systems. This class of generalized nonlinear Lipschitz operators constitutes a very large family (an infinite-dimensional Banach space) of bounded nonlinear operators that describe (part of) the underlying systems. One of the main difficulties in constructing coprine factorizations for nonlinear feedback systems has been in taking care of the nonlinear composite and inverse operators that appear in the closed-loop configuration such that the overall feedback system is well defined in the sense of stability, causality, and uniqueness of the internal signals and such that the coprime factorizations can be achieved. In this paper we show how these difficult issues can be handled nicely under our framework of generalized nonlinear Lipschitz operator theory, at least for a very large class of nonlinear control systems. We give a simple illustrative example to show how these coprime factorizations can actually be characterized and constructed to yield explicit closed-form solutions.
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  • 58
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 387-398 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract In this paper we study the problem of designing a neural network that gives the correct binary representation of a given real number. Previously this problem has been studied by Tank and Hopfield. The network proposed by them exhibits “hysteresis” in the sense that the current vector of the network sometimes converges towards a binary vector that isnot the correct binary representation of the input current. The reason for this is that the network proposed by them has multiple asymptotically stable equilibria. In the present paper, we propose another neural network which has the property that it hasa single, globally attractive equilibrium for almost all values of the input current. Hence, irrespective of the initial conditions of the network, the current vector converges towards the correct binary representation of the input current.
    Materialart: Digitale Medien
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  • 59
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 421-430 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract Concepts of observability and strong observability for singular systems are introduced and characterized geometrically in terms of the system matrices without using the Weierstrass decomposition. Duality relations between observability and controllability and that between reachability and strong observability are established. A canonical form for the action of the output injection group on the set of observable systems is presented.
    Materialart: Digitale Medien
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  • 60
    Digitale Medien
    Digitale Medien
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    Circuits, systems and signal processing 11 (1992), S. 455-492 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract Mathematical morphology is becoming increasingly important in industrial vision applications for object recognition and defect inspection. In this paper we define a new function based on mathematical morphology, which we named the Rotationally Invariant Pecstrum (RIP). The RIP is proven to be invariant under rotation regardless of the shape of the structuring element. This paper also discusses how to use the RIP as an object descriptor and studies the effect of using different structuring elements on recognizing objects of different shapes.
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  • 61
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 493-508 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract This work presents close-form formulas for typical two-dimensional bandselect linear-phase FIR filters (e.g., band-pass, high-pass, and band-stop filters) optimal in the least-squares sense. Cases of both circular and elliptical symmetry are considered. The formulas refer to the coefficients of the frequency sampling form of the frequency response. Therefore they can either be directly used for filter implementation, if the frequency sampling structure is adopted, or used to obtain the impulse response coefficients via an inverse FFT.
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  • 62
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 501-502 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 63
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 503-503 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 64
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 505-505 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 65
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 171-180 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract For ann-by-n nonnegative matrixP, we consider the entrywise harmonic meanH, geometric meanG, and arithmetic meanA, ofP and PT. Simple proofs are given for the inequalities ρ(H)≤ρ(G)≤ p(P)≤ ρ(A), and attention is focused upon characterization of the case of equality in each of these six inequalities. In caseP is irreducible, ρ(G)=p(P) exactly whenP is diagonally similar to a symmetric matrix, and several other equivalent conditions for diagonal symmetrizability ofP are collected together here. Other conditions which arise involve further variations upon symmetry, and may be viewed as algebraic descriptions of various features of symmetry. A tool of interest is a slight variation upon a recent characterization of the Perron root.
    Materialart: Digitale Medien
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  • 66
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 197-212 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract A new class of shorted operators is considered. The shorted operator has an intimate relationship with electrical networks and has been extensively studied. In this work we consider the class of matrices with row and column spans in specified linear subspaces and dominated in a given partial order by a matrixA. If this class of matrices has an unique maximal element under the partial order, then this maximal element is called the shorted matrix ofA relative to the given linear subspaces and the relevant partial order. We study the shorted matrix under the star order of Drazin, the minus order, and also under partial orders induced by the minimum norm and least squares g-inverses. The parallel sum of matrices is intimately related to the shorted matrix and results are given for parallel addition.
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  • 67
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 223-228 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract A new variational characterization of the solution of a matrix Riccati equation is presented. The characterization is given as the maximum Hermitian matrix that makes a certain compound matrix Hermitian positive semidefinite. The shorted operator (Schur complement) applied to the compound matrix produces the Riccati equation.
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  • 68
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 271-300 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract An eigenstructure-based method for direction finding in the presence of sensor gain and phase uncertainties is presented. The method provides estimates of the Directions of Arrival (DOA) of all the radiating sources as well as calibration of the gain and phase of each sensor in the observing array. The technique is not limited to a specific array configuration and can be implemented in a'ny eigenstructure-based DOA system to improve its performance.
    Materialart: Digitale Medien
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  • 69
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 319-341 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract The effects of system parameter uncertainties on system performance are always of great concern to the system designer. It is desirable to knowa priori estimates of the system response, subject to parameter uncertainties. In the following we propose using interval analysis techniques to establish estimates of system performance (e.g., envelopes of time response and frequency response). The results which we obtain constitute generalizations of existing work. Specifically, existing results address systems which are described by linear ordinary differential equations which are endowed with a single parameter belonging to an interval. In the present results we address systems described by linear or nonlinear ordinary difference equations endowed with more than one parameter belonging to intervals.
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  • 70
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 343-364 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract We consider general input-output systems governed by nonlinear operator equations that relate the system's input, state, and output. The systems under consideration need not be of a feedback type. Assuming that the governing equations depend on a parameterA in a linear space that is allowed to vary in a vicinity Nr(A0) of a “nominal” valueA 0, we study conditions under which the system is stable for each A∈Nr (A0), i.e., when the system is robust. By stability we essentially mean that the input-output map is continuous. Depending on the type of continuity used, two concepts of robustness are introduced. The main theorem shows that a certain generalized monotonicity condition imposed on the nominal system combined with a Lipschitz-like condition imposed on the perturbed system guarantees robustness. Moreover, several particular cases of the governing equations are investigated. As examples, we consider (1) a singular system of nonlinear ordinary differential equations (a semistate equation), (2) a feedback system, and (3) a feedback, feedforward system. At the end of this paper some extensions and modifications of the presented theory are discussed.
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  • 71
    Digitale Medien
    Digitale Medien
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    Circuits, systems and signal processing 9 (1990), S. 367-382 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract The subject of this paper is the relation of differential-algebraic equations (DAEs) to vector fields on manifolds. For that reason, we introduce the notion of a regular DAE as a DAE to which a vector field uniquely corresponds. Furthermore, a technique is described which yields a family of manifolds for a given DAE. This socalled family of constraint manifolds allows in turn the formulation of sufficient conditions for the regularity of a DAE, and the definition of the index of a regular DAE. We also state a method for the reduction of higher-index DAEs to lower-index ones that can be solved without introducing additional constants of integration. Finally, the notion of realizability of a given vector field by a regular DAE is introduced, and it is shown that any vector field can be realized by a regular DAE. Throughout this paper the problem of path-tracing is discussed as an illustration of the mathematical phenomena.
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  • 72
    Digitale Medien
    Digitale Medien
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    Circuits, systems and signal processing 9 (1990), S. 409-420 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract The influence of the asymmetry parameterk on the extent and form of the stability region for second-order fixed-point coupled-form digital filters is analyzed. In particular, by extending the results of a previous paper by the same authors, the stability regions for filters with roundoff quantizers are first shown. Then, the corresponding results for filters with either two or four value-truncation quantizers are derived. It turns out that the shape of the stability areas is rather odd because of the asymmetry of the quantization characteristic.
    Materialart: Digitale Medien
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  • 73
    Digitale Medien
    Digitale Medien
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    Circuits, systems and signal processing 9 (1990), S. 435-448 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract Iterated-integral operators calledp-powers arise in the theory of representations of nonlinear systems. In a recent paper, necessary and sufficient conditions are given for such operators to be stable in a standard sense, and it is shown that a well-known sufficient condition is not necessary for allp ≥ 2. Here corresponding results are given for discrete-time cases.
    Materialart: Digitale Medien
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  • 74
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 9 (1990), S. 421-433 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract The paper first briefly reviews some subspace techniques for high-resolution array processing. It is shown that existing high-resolution techniques like the MUSIC algorithm are based on visual inspection of the spatial spectrum. It is not a scientifically valid means of assessing resolution of a spectrum estimator. The paper then proposes a technique based on a combination of optimal processing and signal subspace extraction for high-resolution array processing. Numerical results show that the proposed technique not only achieves superresolution of the spectrum, but also provides power estimates of the arrivals.
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  • 75
    Digitale Medien
    Digitale Medien
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    Circuits, systems and signal processing 9 (1990), S. 449-500 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract Fourier transform algorithms are described using tensor (Kronecker) products and an associated class of permutations. Algebraic properties of tensor products and the related permutations are used to derive variants of the Cooley-Tukey fast Fourier transform algorithm. These algorithms can be implemented by translating tensor products and permutations to programming constructs. An implementation can be matched to a specific computer architecture by selecting the appropriate variant. This methodology is carried out for the Cray X-MP and the AT&T DSP32.
    Materialart: Digitale Medien
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  • 76
    Digitale Medien
    Digitale Medien
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    The Geneva risk and insurance review 17 (1992), S. 7-191 
    ISSN: 1554-9658
    Schlagwort(e): Risk ; Insurance Demand ; Deterministic Transformations ; Stochastic Dominance ; Expected Utility
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Wirtschaftswissenschaften
    Notizen: Abstract The consequences of a change in a random parameter are determined for a decision model with more than one source of randomness. The two cases of independent and stochastically dependent sources of risk are discussed. Four comparative static theorems are given. These state the effect of first degree stochastically dominant shifts or risk decreases for one random variable while the other random variable is held fixed. Deterministic transformations are used to represent random parameter changes. The results are presented in the context of the coinsurance demand model with a risky insurable asset and background risk.
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  • 77
    Digitale Medien
    Digitale Medien
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    The Geneva risk and insurance review 17 (1992), S. 21-33 
    ISSN: 1554-9658
    Schlagwort(e): Insurance Demand ; Multiple Sources of Risk ; Comparative Statics ; Increases in Risk
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Wirtschaftswissenschaften
    Notizen: Abstract In this paper we propose an answer to the following problem of comparative statics in models with multiple sources of risk: How a risk averse agent will change his coinsurance demand when the distribution of the insurable loss is shifted? To answer the question, we first comment on Jack Meyer's results and then we show how an alternate approach leads to more definitive comparative statics.
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  • 78
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    Digitale Medien
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    The Geneva risk and insurance review 17 (1992), S. 35-60 
    ISSN: 1554-9658
    Schlagwort(e): Ambiguity ; Pricing ; Actuaries ; Decision Processes
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Wirtschaftswissenschaften
    Notizen: Abstract This paper reports on the results of a questionnaire study of pricing decisions made by professional actuaries when the probabilities of a loss are either ambiguous or nonambiguous. Theoretical hypotheses derived from the expected utility model were compared with the implications of procedures described by practicing actuaries. Actuaries were asked to act as consultants to a computer manufacturer concerning the price of a warranty. The suggested prices were considerably higher when probabilities were ambiguous than when they were well-specified. These pricing decisions were consistent with the procedures described by actuaries but inconsistent with predictions from expected utility theory when the risks are perfectly correlated. Further insight into the actual decision process is provided by interviews with actuaries and an analysis of comments written on the questionnaire forms.
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  • 79
    Digitale Medien
    Digitale Medien
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    The Geneva risk and insurance review 17 (1992), S. 61-75 
    ISSN: 1554-9658
    Schlagwort(e): Saving ; Borrowing ; Increases in Risk Aversion ; Increases in Risk ; Multivariate NonExpected Utility Model
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Wirtschaftswissenschaften
    Notizen: Abstract We adopt the multivariate non-expected utility approach proposed by Yaari [1986] to provide a characterization of the comparative statics effects of greater risk aversion and of mean-preserving increases in risk on saving and borrowing in the presence of income and interest rate risk. We show that in Yaari's model, it is possible to extend the applicability of the Diamond and Stiglitz [1974] and Kihlstrom and Mirman [1974] (DSKM) single-crossing property to establish a relationship between greater risk aversion and saving (or borrowing) on the basis of the individual's ordinal preferences as long as the two risks are independent. We also demonstrate that the comparative statics effects of a joint mean-preserving increase in random income and interest rate on saving and borrowing can be determined by an extension of the DSKM single-crossing property.
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  • 80
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    Digitale Medien
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    Journal of industrial microbiology and biotechnology 9 (1992), S. 37-43 
    ISSN: 1476-5535
    Schlagwort(e): Linear alkylbenzene sulfonate ; Biodegradation ; Plasmid ; Detergent ; Gene probe
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Linear alkylbenzene sulfonate (LAS) is a widely used anionic surfactant. Although approximately 1 million metric tons of LAS are produced annually, relatively little is known about the bacteria or the genetic factors that control LAS degradation in the environment. The objectives of this research were to: i) compare bacterial populations in wastewater and pristine pond systems; ii) determine the frequency of plasmids in bacteria from these sites; and iii) compare the frequency of DNA sequences coding for aromatic catabolism in isolates from these two sites. Plate counts indicated that exposure to wastewater resulted in higher levels of both heterotrophic bacteria and bacteria capable of growing on LAS containing medium (LAS/YEPG). In addition to higher numbers, a higher proportion of heterotrophs from the wastewater system were capable of growth on LAS/YEPG medium. Thus, the high levels of LAS in the wastewater system apparently selected fro organisms that were able to tolerate and/or degrade, it. Mineralization of14C-ring labelled LAS in any habitat related to the presence of organisms that grew on LAS/YEPG. Although may of these isolates could carry out primary degradation, no isolate, could mineralize14C-ring LAS in pure culture. A higher incidence of plasmids was found in bacteria from the wastewater pond and among bacteria that grew on LAS containing medium. However, the presence of plasmid, DNA did not necessarily confer the ability to degrade LAS nor was the ability to degrade LAS dependent on the presence of a plasmid. The incidence of selected genotypes for aromatic catabolism was similar among isolates on LAS/YEPG at both sites, suggesting that LAS ring degradation may be present in other populations or encoded by alternative sequences. In conclusion, LAS mineralization is mediated by a consortium and the evidence that initial attack of LAS is plasmid mediated is inconclusive.
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  • 81
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    Digitale Medien
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    Journal of industrial microbiology and biotechnology 9 (1992), S. 103-107 
    ISSN: 1476-5535
    Schlagwort(e): Fatty acid bioconversion ; hydroxy octadecenoic acid
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Previously, we reported the discovery of a new compound, 7,10-dihydroxy-8(E)-octadecenoic acid (DOD) which was produced from oleic acid by a new bacterial isolate PR3 [6,7]. The reaction is unique in that it involves a hydroxylation at two positions and a rearrangement of the double bond of the substrate molecule. Now, we have isolated another compound from the reaction mixture determined by GC/MS to be 10-hydroxy-8-octadecenoic acid (HOD). NMR and IR data indicate that the unsaturation is probablycis. The optimum pH and temperature for the production of HOD by strain PR3 were 6.5 and 30°C, about the same as those for DOD. However, the amount of HOD detected remained small throughout an 48-h reaction period during which the amount of DOD increased sharply. At 48 h of reaction, the ratio between HOD∶DOD was 1∶10. HOD may be an intermediate in the biosynthesis of DOD from oleic acid.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 82
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 109-113 
    ISSN: 1476-5535
    Schlagwort(e): Candida blankii ; Biomass ; d-Xylose ; l-Arabinose ; Acetate
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary All fourCandida blankii isolates evaluated for growth in simulated bagasse hemicellulose hydrolysate utilized the sugars and acetic acid completely. The utilization ofd-xylose,l-arabinose and acetic acid were delayed by the presence ofd-glucose, but after glucose depletion the other carbon sources were utilized simultaneously. The maximum specific growth rate of 0.36 h−1 and cell yield of 0.47 g cells/g carbon source assimilate compared with published results obtained withC. utilis. C. blankii appeared superior toC. utilis for biomass production from hemicellulose hydrolysate in that it utilizedl-arabinose and was capable of growth at higher temperatures.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 83
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 115-119 
    ISSN: 1476-5535
    Schlagwort(e): Mycolytic enzymes ; Trichoderma viride ; Protoplasts ; Cochliobolus lunatus ; Fermentation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Microorganism useful for the induction of enzymes lytic towards walls of filamentous fungusCochliobolus lunatus were studies. Production of specificTrichoderma viride mycolytic enzymes was studied in a laboratory fermentor. The product with high chitinase and relatively low protease activity gave better yields ofC. lunatus protoplasts than commercial Novozym 234.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 84
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 121-125 
    ISSN: 1476-5535
    Schlagwort(e): Trichoderma viride ; Cellulase production ; Optimized production medium and parameters
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary A 25-l scale protocol is devised for the optimal secretion and recovery of fungal cellulase. Using a selected higher yieldingTrichoderma viride SMC strain, a protocol consisted of: a) an optimized production medium rich in microcrystalline cellulose (MCC), fortified with 1% (w/v) ammonium sulphate, 0.5% (w/v) soybean flour, 0.1% (v/v) Tween-80 and other trace nutrients; b) optimized physical parameters of production, such as an inoculum containing a homogeneous suspension of 6×107 conidia per 1,28±1°C, pH 4.0±0.5, 300±20 rpm, 11000±1000 l/h aeration, and 170–220 h duration; c) optimal recovery through a filter press (450 l/h rate of filtration) followed by precipitation with 2.5–3.0 volumes of acetone (15°C and basket centrifugation (27°C, 1700 rpm)); and d) vacuum drying (35°C, 4–6 h). This afforded 70% recovery of cellulase in the form of white fluffy powder containing 20000±2000 carboxy methyl cellulase and 1000±50 units filter paperase per g activities, with raw material cost of US$ 8–10 per million carboxy methyl cellulase units. During storage for 18 months at 4°C, ambient temperature and 37°C, the cellulase preparation was found to retain 100, 75 and 60% of its initial activity, respectively.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 85
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 131-135 
    ISSN: 1476-5535
    Schlagwort(e): Cheese ; Starters ; Production ; Alignate
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Calcium alginate beads containingLactococcus lactis cells were used for three batch fermentations of milk or a commercially available growth medium (Gold Complete, Nordica) with the aim of producing concentrated cultures. Repeated fermentations did not significantly increase bead CFU counts which were between 3.3–7.8×1010 CFU/g. During the second and third fermentations, which lasted 6 h each, the bead populations decreased if the incubation was extended over 2 h. There was cell release from the beads. Fermentation media and fermentation time all had an effect on free cell counts, but none of these factors statistically interacted. Free cell counts were higher at the end of fermentations 2 and 3 than in the first fermentation and approximately 50% of the population was in the free state. Free cell counts were higher when the beads were incubated in Gold complete than in milk. Although the total bacterial population of a standard free cell fermentation was always higher than those having immobilized cells, immobilized cell technology did enable the production of dense cultures.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 86
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 247-250 
    ISSN: 1476-5535
    Schlagwort(e): Fructosyl-transferring enzyme ; 1-Kestose ; Fructo-oligosaccharide ; Continuous production
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary β-Fructofuranosidase P-1 fromAureobasidium sp. ATCC 20524, which produces a fructo-oligosaccharide (1-kestose) from sucrose, was immobilized covalently onto alkylamine porous silica with glutaraldehyde at high efficiency (44.4%). Optimum pore diameter of porous silica for immobilization of the enzyme was 91.7 nm. The enzymatic profiles of immobilized enzyme were almost identical to the native one except its stabilities to temperature and metal ions were improved. 1-Kestose was produced continuously and selectively from 40% (w/v) sucrose at fast flow rates by a column packed with the immobilized enzyme for up to 26 days, and the effluent concentration of 1-kestose remained in the range 113–135 mg ml−1.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 87
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 257-260 
    ISSN: 1476-5535
    Schlagwort(e): Polysaccharide ; Fructan ; Gum ; Fermentation ; Bacillus polymyxa ; Sweetener
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Bacillus polymyxa (NRRL-18475) produced a levan-type fructan (B, 2→6 fructofuranoside) when grown on sucrose, sugarcane juice, and sugarbeet molasses. The organism converted about 46% of the fructose moiety of sucrose to levan when grown on sucrose medium, however, the yields of levan from sugarcane juice and beet molasses were much less than sucrose solution. Such sugarcane juice and beet molasses can be made a good substrate for levan production by various modifications. Adding peptone to sugarcane juice or passing beet molasses through a column of gel filtration media improved levan yield to a level almost comparable to that obtained from sucrose.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 88
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 455-475 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Notizen: Abstract Random clone mapping of genomic DNA is a subject of great interest in molecular biology.E. coli has just been mapped and work is progressing on some human chromosomes. In this paper we give estimates of the fraction of genomic DNA which is not clonable by partial digest with a restriction enzyme.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 89
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. 483-484 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 90
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of mathematical biology 52 (1990), S. I 
    ISSN: 1522-9602
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 91
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 3-4 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 92
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 5-6 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 93
    Digitale Medien
    Digitale Medien
    Springer
    Circuits, systems and signal processing 11 (1992), S. 431-439 
    ISSN: 1531-5878
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: Abstract An efficient design of digital differentiators (DD), with a variable frequency range of operation at low and midband frequencies, has been proposed. Implemented as a Taylor structure, a DD designed for orderN can be made to function as a universal configuration giving optimal transfer functions for all possible ordersN, without changing the coefficients.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 94
    Digitale Medien
    Digitale Medien
    Springer
    The Geneva risk and insurance review 15 (1990), S. 5-16 
    ISSN: 1554-9658
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Wirtschaftswissenschaften
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 95
    Digitale Medien
    Digitale Medien
    Springer
    The Geneva risk and insurance review 15 (1990), S. 73-79 
    ISSN: 1554-9658
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Wirtschaftswissenschaften
    Notizen: Abstract When assets are nominal, non-informative rational expectations equilibria exist.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 96
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 11-17 
    ISSN: 1476-5535
    Schlagwort(e): Eicosapentaenoic acid ; Mortierella elongata ; Omega-3 fatty acids
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary WhenMortierella elongata NRRL 5513 was cultured in shake flasks at 25°C, mycelial growth reached a stationary phase at 48 h but maximum eicosapentaenoic acid (EPA) production was observed at 6 days. When incubated at 11°C, EPA production also continued to rise during the stationary phase of growth, reaching a maximum after 10 days. An initial culture pH of 6.1 was found to be optimum for EPA production. The effect of temperature on EPA production was dependent on medium constituents. In glucose and linseed oil supplemented media, optimum temperature for EPA production was 11 and 15°C respectively. A maximum EPA yield of 0.61 g/l was obtained in linseed oil (2%), yeast extract (0.5%) supplemented basal medium. Maximum EPA content as a percentage of lipids (15.12%) was observed when the latter medium was supplemented with 0.25% urea.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 97
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 1-9 
    ISSN: 1476-5535
    Schlagwort(e): Recombinant culture ; Dissolved oxygen ; Biomass ; Plasmid content
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Four recombinant strains ofEscherichia coli were examined for the effects of the dissolved oxygen level on the level of biomass, the plasmid content, and the level of recombinant protein at the stationary phase of batch growth. Strains JM101/pYEJ001, and TB-1/pYEJ001 (encoding chloramphenicol acetyltransferase), and strain TB-1/p1034, and TB-1/pUC19 (encoding β-galactosidase) were grown at the constant dissolved oxygen levels of 0, 50, and 100% air saturation, as well as in the absence of dissolved, oxygen control. The biomass of all strains under constant aerobic conditions was 12–36 times higher than that under anaerobic conditions, but was the same as or slightly higher than that without dissolved oxygen control. The plasmid content in all strains under anaerobic conditions was 2.9–11.7 times higher than that under aerobic conditions. The optimal dissolved oxygen concentration for the specific activity of recombinant proteins was dependent upon the strain. In no strain were constant aerobic conditions optimal. However, because of the effect on biomass, controlled aerobic conditions were optimal for the volumetric activity of recombinant protein in all but one strain.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 98
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 19-25 
    ISSN: 1476-5535
    Schlagwort(e): Schizophyllum commune ; Sclerotium glucanicum ; Branched β-1,3-glucan ; Fan-impeller ; Oxygen limitation ; Process design
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Glucan formation ofSchizophyllum commune andSclerotium glucanicum were investigated. Process data obtained during batch cultivation are presented. Glucan release can be improved by oxygen limitation. Thus, growth and glucan release are influenced by oxygen in opposite ways. Possible pathways of this oxygen-dependent regulation are discussed. A draft-tube/propeller system, rushtonturbine-, fan- and helicon-ribbon-impeller as well as a fundaspi and intermig agitator were tested. The 4-bladed fan impeller withd *=0.64 yielded the best results, since effective bulk mixing is much more important than bubble break up (micromixing) with regard to this system. Fed-batch cultivation always resulted in higher rates of glucan formation than the batch process.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 99
    Digitale Medien
    Digitale Medien
    Springer
    Journal of industrial microbiology and biotechnology 9 (1992), S. 27-36 
    ISSN: 1476-5535
    Schlagwort(e): Genetically engineered microorganisms ; Bovine somatotropin ; Survival ; River
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary The fate in water ofEscherichia coli K-12 strain LBB269, both plasmid-free and carrying the recombinant plasmid pBGH1, was studied.E. coli K-12 strain LBB269 (pBGH1) is a nalidixic acid resistant derivative of W3110G (pBGH1), the microorganism used by Monsanto Company for the commercial production of bovine somatotropin. Water samples were obtained from the Missouri River and from the Monsanto Life Sciences Research Center aqueous waste basin. Strains LBB269 and LBB269 (pBGH1) were grown in fermentation vessel under bovine somatotropin (BST) production conditions, and inoculated into the water samples. The inoculated water samples were incubated, at 26°C, and the number of viableE. coli cells was determined as a function of time. In sterile water from both sources, the two strains remained, at a constant level for at least 28 days; LBB269 (pBGH1) remained at a constant level in sterile water for at least 300 days. In non-sterile water from both sources, the two strains declined from an initial concentration of about 3.0×106 cells per ml to less than 10 cells per ml in 147 h. The study conditions did not adversely affect the populations of indigenous microorganisms. The selective loss of strains LBB269 and LBB269 (pBGH1) demonstrates that theseE. coli strains do not survive in environmental sources of water. In addition, it was observed that the presence of pBGH1 had essentially no effect on the disappearance of strain LBB269 from either source of water.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 100
    ISSN: 1476-5535
    Schlagwort(e): Protein kinase C (PKC) ; Phorbol ester ; Methylpendolmycin ; Pendolmycin ; Actinomycete
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary During the course of screening for inhibitors of phorbol ester binding to protein kinase C, several actinomycete cultures were discovered that produce active metabolites. HPLC coupled to photodiode array and LC/MS techniques were applied to broth extracts to identify the presence of indolactams belonging to the teleocidin family. Various members of this family were rapidly identified from crude broth extracts using a combination of these spectroanalytical procedures. An analytical HPLC system was developed to optimize separation of teleocidin, A and B analogues directly from ethyl acetate extracts of whole broth cultures. This technique allowed us to identify a novel homologue of pendolmycin and demonstrated the utility of photodiode array HPLC coupled with LC/MS as an intial analytical tool in the analyses of these secondary metabolites produced by soil microorganisms.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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