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  • Springer  (110,857)
  • Nature Publishing Group  (4,348)
  • 2020-2024  (95)
  • 1995-1999  (66,687)
  • 1980-1984  (48,423)
  • 1925-1929
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Year
  • 1
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    Datenschutz als Vermögensrecht (2020)
    Springer Nature | Springer
    Details
    Publication Date: 2021-12-24
    Description: In diesem Open-Access-Buch untersucht die Autorin die Fortentwicklung des Datenschutzrechts zu einem Datenhandelsrecht. Sie stellt dar, wie Personendaten bereits heute gehandelt werden können und wo sich Problemfelder insbesondere vor dem Hintergrund von Big Data ergeben. Außerdem veranschaulicht sie bestehende Reformvorschläge, wie z. B. die Einführung eines sogenannten „Dateneigentums“, und misst dies an einer vertieften Analyse des Interessendreiecks beim Datenhandel. Aus der Einordnung in eine Gesamtanalyse lassen sich wichtige Handlungsempfehlungen ableiten.
    Keywords: IT Law, Media Law, Intellectual Property ; Civil Law ; Public Law ; Big Data ; Persönlichkeitsrecht ; Datenverarbeitung ; Datenhandelsrecht ; Immaterialgüterrecht ; Open Access ; Entertainment & media law ; Systems of law: civil codes / civil law ; Private or civil law: general ; bic Book Industry Communication::L Law::LN Laws of Specific jurisdictions::LNJ Entertainment & media law ; bic Book Industry Communication::L Law::LA Jurisprudence & general issues::LAF Systems of law::LAFD Civil codes / Civil law ; bic Book Industry Communication::L Law::LN Laws of Specific jurisdictions::LND Constitutional & administrative law
    Language: German
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  • 2
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    Charting Spiritual Care (2020)
    Springer Nature | Springer
    Details
    Publication Date: 2024-03-31
    Description: This open access volume is the first academic book on the controversial issue of including spiritual care in integrated electronic medical records (EMR). Based on an international study group comprising researchers from Europe (The Netherlands, Belgium and Switzerland), the United States, Canada, and Australia, this edited collection provides an overview of different charting practices and experiences in various countries and healthcare contexts. Encompassing case studies and analyses of theological, ethical, legal, healthcare policy, and practical issues, the volume is a groundbreaking reference for future discussion, research, and strategic planning for inter- or multi-faith healthcare chaplains and other spiritual care providers involved in the new field of documenting spiritual care in EMR. Topics explored among the chapters include: Spiritual Care Charting/Documenting/Recording/Assessment Charting Spiritual Care: Psychiatric and Psychotherapeutic Aspects Palliative Chaplain Spiritual Assessment Progress Notes Charting Spiritual Care: Ethical Perspectives Charting Spiritual Care in Digital Health: Analyses and Perspectives Charting Spiritual Care: The Emerging Role of Chaplaincy Records in Global Health Care is an essential resource for researchers in interprofessional spiritual care and healthcare chaplaincy, healthcare chaplains and other spiritual caregivers (nurses, physicians, psychologists, etc.), practical theologians and health ethicists, and church and denominational representatives.
    Keywords: Health Services Research ; Religion and Health ; Religion and Psychology ; Theory of Medicine/Bioethics ; Health Sciences ; Sociology of Religion ; Psychology of Religion and Spirituality ; healthcare chaplaincy ; spiritual care ; spirituality and health ; professionalization of spiritual care ; integration of spirituality in health care ; electronic medical records (EMR) ; pastoral confidentiality ; models of recording spiritual care ; outcome-oriented chapliancy ; digital health ; health ethics ; religion and health ; interprofessional spiritual care ; legal and theoretical perspectives ; open access ; Health systems & services ; Religious issues & debates ; Psychology ; Religion: general ; Bioethics ; Medicine: general issues ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBP Health systems and services ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRA Religion: general::QRAM Religious issues and debates ; thema EDItEUR::J Society and Social Sciences::JM Psychology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAD Bioethics
    Language: English
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  • 3
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    Austenitic TRIP/TWIP Steels and Steel-Zirconia Composites (2020)
    Springer Nature | Springer
    Details
    Publication Date: 2024-04-11
    Description: This open access book presents a collection of the most up-to-date research results in the field of steel development with a focus on pioneering alloy concepts that result in previously unattainable materials properties. Specifically, it gives a detailed overview of the marriage of high-performance steels of the highest strength and form-ability with damage-tolerant zirconia ceramics by innovative manufacturing technologies, thereby yielding a new class of high-performance composite materials. This book describes how new high-alloy stainless TRIP/TWIP steels (TRIP: TRansformation-Induced Plasticity, TWIP: TWinning-induced Plasticity) are combined with zirconium dioxide ceramics in powder metallurgical routes and via melt infiltration to form novel TRIP-matrix composites. This work also provides a timely perspective on new compact and damage-tolerant composite materials, filigree light-weight structures as well as gradient materials, and a close understanding of the mechanisms of the phase transformations. With a detailed application analysis of state-of-the-art methods in spatial and temporal high-resolution structural analysis, in combination with advanced simulation and modelling, this edited volume is ideal for researchers and engineers working in modern steel development, as well as for graduate students of metallurgy and materials science and engineering.
    Keywords: Structural Materials ; Metallic Materials ; Ceramics, Glass, Composites, Natural Materials ; Materials Engineering ; Mathematical Modeling and Industrial Mathematics ; Metals and Alloys ; Ceramics ; Steel-Matrix Composite ; Austenitic Stainless Steels ; Powder Metallurgy ; Fracture Toughness ; Mechanical Modeling ; Melt Flow Behavior ; CrMnNi Steels ; Ceramic Casting ; Melt Infiltration ; Open Access ; Materials science ; Structural engineering ; Metals technology / metallurgy ; Industrial chemistry & chemical engineering ; Mathematical modelling ; Maths for engineers ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering::TDCQ Ceramic and glass technology ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics::PBWH Mathematical modelling
    Language: English
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  • 4
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    The Limits of Art (2020)
    Springer Nature | Springer
    Details
    Publication Date: 2024-04-08
    Description: This open access book is about exploring interesting borderline cases of art. It discusses the cases of gustatory and olfactory artworks (focusing on food), proprioceptive artworks (dance, martial arts, and rock climbing qua proprioceptive experiences), intellectual artworks (philosophical and scientific theories), as well as the vague limits between painting and photography. The book focuses on the author’s research about what counts as art and what does not, as well as on the nature of these limits. Overall, the author defends a very inclusive view, 'extending' the limits of art, and he argues for its virtues. Some of the limits discussed concern our senses (our different perceptual modalities), some concern vagueness and fuzzy boundaries between different types of works of art, some concern the amount of human intention and intervention in the process of creation of an artwork, and some concern the border between art and science. In these various ways, by understanding better such borderline cases, Benovsky suggests that we get a better grip on an understanding of the nature of art.
    Keywords: Analytic Philosophy ; Aesthetics ; Fine Arts ; Fine Art ; Proprioceptive art ; Gustatory art ; Olfactory art ; Visual art ; Intellectual art ; Sensory dependence ; Art and Photography ; Art and Philosophy ; Types of art ; Non-visual and non-auditory artworks ; analyzing paintings and photographs ; borderline cases of art ; vague limits between painting and photography ; Open Access ; Analytical philosophy & Logical Positivism ; Philosophy: aesthetics ; Fine arts: art forms ; bic Book Industry Communication::H Humanities::HP Philosophy::HPC History of Western philosophy::HPCF Western philosophy, from c 1900 -::HPCF5 Analytical philosophy & Logical Positivism ; bic Book Industry Communication::H Humanities::HP Philosophy::HPN Philosophy: aesthetics ; bic Book Industry Communication::A The arts::AF Art forms ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDH Philosophical traditions and schools of thought::QDHR Western philosophy from c 1800::QDHR9 Analytical philosophy and Logical Positivism ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTN Philosophy: aesthetics ; thema EDItEUR::A The Arts::AF The Arts: art forms
    Language: English
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  • 5
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    Foundations of Software Science and Computation Structures (2020)
    Springer Nature | Springer
    Details
    Publication Date: 2024-04-04
    Description: This open access book constitutes the proceedings of the 23rd International Conference on Foundations of Software Science and Computational Structures, FOSSACS 2020, which took place in Dublin, Ireland, in April 2020, and was held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2020. The 31 regular papers presented in this volume were carefully reviewed and selected from 98 submissions. The papers cover topics such as categorical models and logics; language theory, automata, and games; modal, spatial, and temporal logics; type theory and proof theory; concurrency theory and process calculi; rewriting theory; semantics of programming languages; program analysis, correctness, transformation, and verification; logics of programming; software specification and refinement; models of concurrent, reactive, stochastic, distributed, hybrid, and mobile systems; emerging models of computation; logical aspects of computational complexity; models of software security; and logical foundations of data bases.​
    Keywords: Mathematical Logic and Foundations ; Discrete Mathematics in Computer Science ; Programming Languages, Compilers, Interpreters ; Programming Techniques ; Logic in AI ; Computer Systems Organization and Communication Networks ; categorical models and logics ; language theory, automata, and games ; modal, spatial, and temporal logics ; type theory and proof theory ; concurrency theory and process calculi ; rewriting theory ; semantics of programming languages ; program analysis, correctness, transformation, and verification ; logics of programming ; software specification and refinement ; emerging models of computation ; logical aspects of computational complexity ; models of software security ; logical foundations of data bases ; mathematics ; artificial intellegence ; formal logic ; linguistics ; Mathematical foundations ; Mathematical logic ; Discrete mathematics ; Maths for computer scientists ; Programming & scripting languages: general ; Compilers & interpreters ; Computer programming / software engineering ; Artificial intelligence ; Computer networking & communications ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBC Mathematical foundations ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBD Discrete mathematics ; thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMX Programming and scripting languages: general ; thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence ; thema EDItEUR::U Computing and Information Technology::UT Computer networking and communications
    Language: English
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  • 6
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    Haptics: Science, Technology, Applications (2020)
    Springer Nature | Springer
    Details
    Publication Date: 2024-04-14
    Description: This open access book constitutes the proceedings of the 12th International Conference on Human Haptic Sensing and Touch Enabled Computer Applications, EuroHaptics 2020, held in Leiden, The Netherlands, in September 2020. The 60 papers presented in this volume were carefully reviewed and selected from 111 submissions. The were organized in topical sections on haptic science, haptic technology, and haptic applications. This year's focus is on accessibility.
    Keywords: User Interfaces and Human Computer Interaction ; Robotics ; Special Purpose and Application-Based Systems ; Information Systems Applications (incl. Internet) ; Image Processing and Computer Vision ; Computer and Information Systems Applications ; Computer Vision ; communication systems ; computer networks ; data communication systems ; display devices ; engineering ; haptic devices ; haptic interfaces ; human engineering ; Human-Computer Interaction (HCI) ; mobile computing ; network protocols ; robotics ; signal processing ; telecommunication networks ; user interfaces ; virtual reality ; wireless telecommunication systems ; User interface design & usability ; Artificial intelligence ; Expert systems / knowledge-based systems ; Information retrieval ; Internet searching ; Image processing ; Computer vision ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYZ Human–computer interaction::UYZG User interface design and usability ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence::UYQE Expert systems / knowledge-based systems ; thema EDItEUR::U Computing and Information Technology::UN Databases::UNH Information retrieval ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYT Image processing
    Language: English
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  • 7
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    Massive dolomites in the Messinian evaporitic sequence (Sicily, Italy): multi-analytical characterization and implications for the dolomitization processes (2020)
    Springer
    Details
    Publication Date: 2023-10-26
    Description: A combined geochemical, mineralogical, petrographic and geological approach has allowed to constrain the dolomitization process responsible for the formation of massive dolomitic body within the Messinian evaporitic series. We focused our investigations on an example of massive dolomite body, outcropping over the marginal area of the evaporitic basin in the Peloritani Mountains (NE area of Sicily region, Italy). Field observations allowed recognizing several sedimentary structures, such as erosion surfaces, lenses of conglomerates and ripples highlighting a clastic origin. The petrographic study revealed fne-grained and massive structure, scarce porosity, light to pink color and absence of micro-fossils. The chondritenormalized trace element pattern shows a general enrichment in LREE and depletion in HREE. The isotopic signatures of the studied dolomites (δ18O=– 4.38–1.24‰, V-PDB; δ13C=– 1.48–1.94‰, V-PDB) are comparable with those of type-3 “Calcare di Base” which is the common reference to record the Messinian salinity crisis. The positive co-variant relationship between the δ18O and δ13C values suggests a dolomitization process in the seawater/freshwater mixing zone. The occurrence of the studied dolomites in the evaporitic sequence coupled with the results we gained point towards an origin from “early diagenetic” processes. As a consequence, a model explaining the genetic mechanism for the studied dolomitic rocks can be essentially summarized as: (1) the massive dolostones were originally deposited as evaporitic limestones under rather highsalinity conditions; (2) the dolomitization process occurred in the seawater/freshwater mixing zone that provided Mg-rich fuids over uplifted submarine masses.
    Description: Published
    Description: id 29
    Description: 7SR AMBIENTE – Servizi e ricerca per la società
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 8
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    Estimating eruptive parameters and related uncertainties for pyroclastic density currents deposits: worked examples from Somma-Vesuvius (Italy) (2020)
    Springer
    Details
    Publication Date: 2023-10-31
    Description: The quantification of the maximum runout, invaded area, volume, and total grain-size distribution (TGSD) of pyroclastic density currents (PDC) is a critically important task because such parameters represent the needed necessary input quantities for physical modeling and hazard assessment of PDCs. In this work, new and well-established methods for the quantification of these parameters are applied to a large stratigraphic dataset of three PDC units from two eruptions of Somma-Vesuvius (the AD 79 Pompeii and the AD 472 Pollena eruptions), representative of a large spectrum of transport and depositional processes. Maximum runout and invaded area are defined on the basis of the available volcanological and topographical constraints. The related uncertainties are evaluated with an expert judgment procedure, which considersed the different sectors of the volcano separately. Quite large uncertainty estimates of dispersal area (20–40%) may have important implications in terms of hazard assessment. The testing of different methods for estimating the volume (and mass) of a PDC deposit suggests that integration, over the invaded area, of thickness (and deposit density) data using the triangulated irregular network method can minimize and localize data extrapolation. Such calculations, however, bear an intrinsic additional uncertainty (at least 10% of the total PDC deposit) related to loss or new formation of fine material during transport (at least 10% of the total PDC deposit). Different interpolation methods for TGSD produce multimodal distributions, likely reflecting the different response of each grain size class to transport and deposition processes. These data, when integrated with information on the related co-ignimbrite deposits, can give a more accurate picture of the pyroclastic mixture feeding the current.
    Description: Published
    Description: Id 65
    Description: 5V. Processi eruttivi e post-eruttivi
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 9
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    Simulation of seismic ground motion fields via object-oriented spatial statistics with an application in Northern Italy (2020)
    Springer
    Details
    Publication Date: 2023-11-21
    Description: This work offers a novel methodological framework to address the problem of generating data-driven earthquake shaking fields at different vibration periods, which are key to support decision making and civil protection planning. We propose to analyse the entire profiles of spectral accelerations and project their information content to unsampled locations in the system, based on the theory of Object Oriented Spatial Statistics. The proposed methodology combines a non-ergodic ground motion model with a fully functional model for the residual term, the latter consisting of (i) the spatially-varying systematic effects due to source, site and path, and (ii) the remaining aleatory error. The proposed methodology allows to generate multiple shaking scenarios conditioned on the data, jointly and consistently for all the vibration periods, overcoming the intrinsic limitations of existing multivariate approaches to the problem. The approach is tested on a vast dataset of ground motion records collected in the study-area of the Po Plain (Northern Italy), for which a region-specific fully non-ergodic GMM was previously calibrated. Our validation tests demonstrate the potentiality of the approach, which is capable to effectively simulate spectral acceleration profiles, while keeping the ability to capture the main physical features of ground motion patterns in the region.
    Description: Published
    Description: 1607–1627
    Description: 5T. Sismologia, geofisica e geologia per l'ingegneria sismica
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 10
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    Biological Clocks and!Rhythms in Polar Organisms (2020)
    Springer
    In:  EPIC3Polar Night Marine Ecology_ Life and Light in the Dead of Night, Advances in Polar Ecology, Switzerland, Springer, pp. 217-240, ISBN: 978-3-030-33208-2
    Details
    Publication Date: 2024-05-13
    Description: Biological clocks are universal to all living organisms on Earth. Their ubiquity is testament to their importance to life: from cells to organs and from the simplest cyanobacteria to plants and primates, they are central to orchestrating life on this planet. Biological clocks are usually set by the day–night cycle, so what happens in polar regions during the Polar Night or Polar Day when there are periods of 24! hours of darkness or light? How would a biological clock function without a timekeeper!cycle? This chapter details evidence that biological clocks are central to structuring daily and seasonal activities in organisms at high latitudes. Importantly, despite a strongly reduced or absent day–night cycle, biological clocks in the Polar Night still appear to be regulated by background illumination. Here we explore evidence for highly cyclic activity, from behaviour patterns to clock gene expression, in copepods, krill and bivalves. The ultimate goal will be to understand the role of endogenous clocks in driving important daily and seasonal life cycle functions and to determine scope for plasticity in a rapidly changing environment.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Inbook , peerRev
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  • 11
    Electronic Resource
    Electronic Resource
    Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 490-492 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] TPA, an activator of protein kinase C, triggers platelet aggregation as well as the secretion of [14C]-serotonin from platelets11-13. The response to activation by 1 mM TPA at 37 C, with constant stirring, is more gradual than the response to activation by O.1Uml-1 thrombin and maximal aggregation ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/306490a0
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  • 12
    Electronic Resource
    Electronic Resource
    Electron densities in active galaxies (reply) (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 503-503 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] GASKELL REPLIES-While recognizing that the main point of Jordan's comment is to attempt to correct the allegedly misleading generalizations made by Fair all1 and myself2, I must state that the size of the forbidden line emitting region in Fairall 427 is not an open question. If one looks at ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/306503c0
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  • 13
    Electronic Resource
    Electronic Resource
    New gene provokes questions (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 731-731 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE article on page 756 from Dr P. W. J. Rigby's group at Imperial College is an intriguing document which is plainly of the utmost importance, but for reasons which, at this stage, are not fully apparent. The obvious difficulty is that the observations described bear on such a variety of important ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/306731a0
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  • 14
    Electronic Resource
    Electronic Resource
    Just how objective is science? (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 727-730 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WRITING some thirty years ago, Hermann Bondi suggested that in astronomy, observations had proven a less reliable arbiter of hypotheses than had theoretical considerations1 . Subsequent historical studies have widened and deepened knowledge of some of the instances cited by Bondi and have uncovered ...
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    URL: http://dx.doi.org/10.1038/306727a0
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  • 15
    Electronic Resource
    Electronic Resource
    Oncogenesis: Paradox and paradigm: the message and meaning of myc (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 733-736 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE cellular myc gene may, depending on your point of view, be seen as either the most illuminating or the most confusing of the cellular oncogenes. The promise of illumination lies in the overwhelming circumstantial evidence that c-myc activation in some lymphoid tumours is a direct subversion, ...
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    URL: http://dx.doi.org/10.1038/306733a0
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  • 16
    Electronic Resource
    Electronic Resource
    Applied molecular biology: Lignin biodegradation becomes biochemistry (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 737-738 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] AFTER some years of increasing interest, rapid progress is now being made in the understanding of lignin biodegradation. Research in a number of laboratories has culminated in the isolation by T.K. Kirk and Ming Tien of a purified enzyme able to depolymerize lignin1. This enzyme, isolated from the ...
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    URL: http://dx.doi.org/10.1038/306737a0
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  • 17
    Electronic Resource
    Electronic Resource
    Neurophramacology: Endogenous opioid peptides and pain mechanisms: a complex relationship (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 739-740 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ALTHOUGH an ever-increasing number of pharmacologically active peptides are being found in neurones of the central nervous system, it is still not proving possible to find out precisely what neuro-transmitter or neuromodulator functions they perform. This may not be so surprising when one remembers ...
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    URL: http://dx.doi.org/10.1038/306739a0
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  • 18
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    Electronic Resource
    100 years ago (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 741-741 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN a letter dated Tokio, October 3, Prof. James Main Dixon writes:- "During the two or three days at the end of August we enjoyed fine dry weather, but the sun was copper-coloured and had no brightness. When we got to Nikko, the people came to us to inquire if some catastrophe were impending, for ...
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    URL: http://dx.doi.org/10.1038/306741a0
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  • 19
    Electronic Resource
    Electronic Resource
    Cancer and cell senescence (reply) (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 742-742 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] CAIRNS AND LOGAN REPLY - In the first half of his letter, Dr Holliday gives three reasons for thinking that programmed cell senescence is not a protection against the development of cancer. We believe that each of the arguments is fallacious. The common human cancers, as described in textbooks of ...
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    URL: http://dx.doi.org/10.1038/306742b0
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  • 20
    Electronic Resource
    Electronic Resource
    Dating the Crucifixion (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 743-746 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The date of the Crucifixion has been debated for many years, but there has been no agreement on the year nor the day. Astronomical calculations have now been used to reconstruct the Jewish calendar in the first century AD and to date a lunar eclipse that biblical and other references ...
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    URL: http://dx.doi.org/10.1038/306743a0
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  • 21
    Electronic Resource
    Electronic Resource
    Composition measurements of tropospheric ions (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 747-751 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Tropospheric ions are of considerable interest as they have the potential to induce aerosol formation and because in situ measurements of their composition are a powerful tool for neutral trace gas detection. The first measurements of tropospheric ion compositions are now ...
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    URL: http://dx.doi.org/10.1038/306747a0
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    Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 756-760 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A cDNA clone corresponding to a mRNA present at elevated levels in transformed fibroblasts encodes a Qa / Tla class I major histocompatibility complex (MHC) antigen. High levels of this mRNA are found in all tumour cells tested; the transcript can undergo alternative splicing; and a repetitive ...
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    Photon oscillations and cosmic background radiation (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 765-766 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Our model of photon oscillations is a simple extension of the standard gauge theory of strong interactions wherein an additional gauged U'(l) factor is adjoined to the usual spontaneously broken SU(3) xSU(2) xU(1). Known particles transform trivially under U'(1). At this point, the model involves ...
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    Combustion-generated carbon particles in the Arctic atmosphere (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 768-770 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Graphitic particles can only be produced by combustion processes. If one excludes natural burning processes that are not expected to be a significant source during winter and spring when Arctic haze is at a maximum, then one can attribute these particles directly to anthropogenic combustion ...
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    The macromolecular states of solvent-swollen and dry coal (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 772-773 
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    Notes: [Auszug] More than half a century ago it was postulated that coal was a 'polymeric' or macromolecular substance1-3. However, the evidence has not been completely convincing, and the particular nature of the macromolecular state has remained uncertain. Boddy4 found that coals, which normally exhibit brittle ...
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    β -Globin gene inactivation by DNA translocation in γβ -thalassaemi (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 662-666 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The β-globin gene present on the deletion locus in a Dutch γβ-thalassaemic patient was found to be identical to the normal β-globin gene with respect to DNA sequence and its transcription in HeLa cells. DNase I sensitivity and methylation experiments show that the affected ...
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    Sunspot index infers a small relict magnetic field in the Sun's core (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 670-673 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The lines in the spectrum of the Zurich sunspot index in the interval 100 〈 t 〈 8 yr (where t is the period) match those of a model in which a 22-yr carrier 'wave' representing the Hale 22-yr cycle is amplitude modulated (AM) at the 90 yr (Gleissburg) period in the presence of a small but ...
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    Reaction of NO 2 with NaCl and atmospheric implications of NOCl formation (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 676-677 
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    Notes: [Auszug] An observed deficiency of chloride ions in coastal aerosols in some locations has been attributed to a reaction of HNO3 or NO2 with NaCl (refs 7-12). Gaseous HC1 has been assumed to be the product based on studies11,12 showing that 0.1-100 p.p.m. NO2 reacted rapidly with moist NaCl aerosols to ...
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    Isotopic evidence from the eastern Canadian shield for geochemical discontinuity in the Proterozoic mantle (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 679-680 
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    Notes: [Auszug] The anorthosites were emplaced into presumed Archaean quartzof eldspathic gneisses, although in large areas of the Grenville Province, both massifs and basement rocks were reworked during late Proterozoic (about 1,000 Myr) Grenvillian metamorphism5. The Adirondack anorthosite may have crystallized ...
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    Evidence from earliest known erinaceomorph basicranium that insectivorans and primates are not closely related (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 683-684 
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    Notes: [Auszug] The basicranium is part of a dorsoventrally crushed skull and upper dentition of Diacodon alticuspis, an erinaceomorph from the Lower Eocene (Wasatchian North American Land Mammal Age, about 52 Myr BP) of northern New Mexico7. The specimen was collected in 1946 by an American Museum of Natural ...
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    Substance P in the ascending cholinergic reticular system (1983)
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    Nature 306 (1983), S. 688-691 
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    Notes: [Auszug] Indirect immunofluorescence techniques were used to identify the cholinergic and substance P-containing neurones of the midbrain and pontine tegmentum of young adult male rats (150-200 g, Wistar). To increase the levels of ChAT and substance P in cell bodies, the animals were given an injection of ...
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    Chemical basis of antigenic variation in foot-and-mouth disease virus (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 694-697 
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    Notes: [Auszug] There is considerable evidence that the major immunogen is situated on VP1, one of the four capsid proteins1-5. Furthermore, the position of the major immunogenic site on VP1 of virus of serotype 0 has been shown to lie within the amino acid tract 141-1606-8. The same region of VP1 from other ...
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    Mimicking the alloantigenicity of proteins with chemically synthesized peptides differing in single amino acids (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 697-699 
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    Notes: [Auszug] The Thy-1 glycoprotein exists in two allotypic forms, Thy 1.1 and Thy 1.2 (ref. 4). It has been proposed that an arginine residue at position 89 corresponds to the Thy 1.1 allotype and a glutamine residue to Thy 1.2 (ref. 5). Since the two proteins differ by only a single residue, they offered a ...
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    Instability of the Trypanosoma brucei rhodesiense metacyclic variable antigen repertoire (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 699-701 
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    Notes: [Auszug] Trypanosoma brucei rhodesiense, causative agent of East African sleeping sickness in man, also infects domestic and game animals. As the sole criterion for distinguishing T. b. rhodesiense from T. b. brucei is the former's infectivity to man, any T. brucei group stock isolated from reservoir host ...
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    A yeast gene encoding a protein homologous to the human c- has/bas proto-oncogene product (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 704-707 
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    Notes: [Auszug] Previously we have isolated two recombinant plasmids (pYA102 and pYA208) containing overlapping DNA fragments which harbour the yeast actin gene8,9. In studying the region 5' to the actin gene we detected another gene whose transcription product is a polysomal RNA coding for a protein of 20,000 ...
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    ras -Related gene sequences identified and isolated from Saccharomyces cerevisiae (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 707-709 
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    Notes: [Auszug] The transforming genes of Harvey and Kirsten murine sarcoma viruses have been named ras oncogenes because these two oncogenic retroviruses were originally isolated by passage of murine leukaemia viruses in rats1. The ras oncogene of Harvey murine sarcoma virus has been named v-rasH and that of ...
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    Selective unfolding of erythroid chromatin in the region of the active β -globin gene (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 709-712 
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    Notes: [Auszug] We have previously shown that linker histone (H1 and H5) induced chromatin condensation, as measured by electron microscopy, is directly proportional to the sedimentation rate5. Here we have used the sedimentation rate of chromatin as the primary measure of its higher order folding. Our ...
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    Staying neutral on evolution (1983)
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    Nature 306 (1983), S. 713-714 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THIS is the book we have been waiting for. Fifteen years ago, the neutral theory was proposed by Kimura, and independently by King and Jukes. In Kimura's formulation, it made two assertions. First, chance events have been more important than natural selection in bringing about evolutionary changes ...
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    Hazy atmosphere (1983)
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    Nature 306 (1983), S. 714-714 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE realization in the early 1970s that free radicals are a normal component of the Earth's lower atmosphere revolutionized our understanding of atmospheric chemistry and its role in the larger biogeo-chemical cycling of the elements. However, the advances made in this field over the past decade ...
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    The good, the bad and the ugly (1983)
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    Nature 306 (1983), S. 714-715 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] As most historians portray it, science is a linear sequence of triumphant discoveries. Occasionally we hear of scientists who were mistaken, just so long as they were mistaken in big ways. But most scientists fail in the most literal sense of this term. They may publish a few papers, but these ...
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    [Book Reviews ‘picture story’] (1983)
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    Nature 306 (1983), S. 715-715 
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    Notes: [Auszug] GLIMPSE of 1986 - an artist's impression of the International Solar Polar Mission spacecraft (which is now completed) atop a Centaur upper stage after its deployment from the Space Shuttle. The illustration is taken from a new publication of the European Space Agency, The International Solar Polar ...
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    Pensioners mean problems (1983)
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    Nature 306 (1983), S. 521-521 
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    Notes: [Auszug] How, in the long run, can a modern state hope to deal equitably with its pensioners, especially if a substantial fraction of its putatively working population is forced into premature pensionhood by unemployment? And what if the social burden of the unemployment rolls will in any case be made ...
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    What rights for animals? (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 522-522 
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    Notes: [Auszug] ROBERT Nozick, the Harvard University philosopher, wrote last week in the New York Times that animal rights is a subject that seems to attract cranks. The distinguishing feature of a crank, he was quick to point out, is not merely preoccupation with a single issue; the solving of the world's ...
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    Science for the young (1983)
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    Nature 306 (1983), S. 522-522 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] How would you find out whether a ball that bounces best on one surface bounces best on all surfaces? How would you tell why a snail will not cross a ring of salty water? These are some of the questions that have been put to 11-year-olds in British primary schools by a group of investigators from ...
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    UK agriculture research: Plans for 250 jobs to go (1983)
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    Nature 306 (1983), S. 523-523 
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    Notes: [Auszug] THE Agricultural and Food Research Council (AFRC) has now completed its strategic plan, intended as an adaptation to the expected substantial drop in its share of the science budget over the next few years. The plan, which has not yet been ratified, will be discussed next week at a meeting of ...
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    Words from space (1983)
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    Nature 306 (1983), S. 523-523 
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    Notes: [Auszug] NATURE is able today to report the exciting news that there is life - of a kind - in outer space. Through the marvels of modern communications, President Ronald Reagan, Chancellor Helmut Kohl of West Germany, your correspondent and a few other European journalists were able on Monday to direct ...
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    Institute settles lawsuit (1983)
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    Nature 306 (1983), S. 524-524 
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    Notes: [Auszug] THE Linus Pauling Institute of Science and Medicine in Palo Alto, California, has settled yet another lawsuit brought by a former employee who claimed to have been dismissed from a tenured research position. Dr Fred West all, who worked at the institute in 1978 and 1979, had accused Pauling of ...
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    World Unification Church: Mixed motives at conclave (1983)
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    Nature 306 (1983), S. 524-524 
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    Notes: [Auszug] Chicago UNDAUNTED by 12 years of intermittent controversy, distinguished academics continue to flock to the annual conference on "the unity of the sciences" sponsored by Reverend Sun Myung Moon's Unification Church. This year's conference, held here last week, heard the Nobel economist F.A. Hayek ...
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    UK environment: Conservation plans go awry (1983)
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    Nature 306 (1983), S. 525-525 
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    Notes: [Auszug] THE Wildlife and Countryside Act, introduced two years ago, has run into serious trouble. British conservation groups are complaining that the act fails to provide adequate protection to places designated by the Nature Conservancy Council (NCC) as Sites of Special Scientific Interest (SSSIs). The ...
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    Finnish environment: New ministry's teething problems (1983)
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    Nature 306 (1983), S. 525-525 
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    Notes: [Auszug] FINLAND is planning a massive modification of its environmental legislation over the next ten years. At present, the laws of environmental protection are a confused collection of ad hoc acts introduced piecemeal to cope with specific problems. The need for a legislative review was underlined by the ...
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    European biotechnology: Surplus food into feedstock (1983)
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    Nature 306 (1983), S. 526-526 
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    Notes: [Auszug] OUT of the political and economic gloom over the Athens summit earlier this week, where European Prime Ministers were attempting to thrash out a solution to the European Community's burgeoning "budget problem", officials were hoping for a little "green light" for biotechnology. The heads of ...
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    French computers: Double-deal at Orsay (1983)
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    Nature 306 (1983), S. 526-526 
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    Notes: [Auszug] EVEN if French academic computing power is behind that of the United Kingdom and West Germany (see Nature304,298; 1983), things may be looking up. After two years of often bitter negotiations, the biggest scientific campus in France - the Universit de Paris Sud at Orsay - has at last been granted a ...
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    Australian telecommunications: Private sector at arms' length (1983)
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    Nature 306 (1983), S. 527-527 
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    Notes: [Auszug] Canberra THE Labour Government has been busily reversing the free-market bent of Mr Malcolm Eraser's policy on telecommunications in order to keep it in the public sector. The latest policy reversal is the decision on 15 November to retain full ownership of Aussat Pty Ltd, the company set up to ...
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    Laboratory animals: Huxley attacks “animal rightists” (1983)
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    Nature 306 (1983), S. 527-527 
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    Notes: [Auszug] IN a stout defence of laboratory animal experiments, Sir Andrew Huxley, president of the Royal Society, last week let slip that he personally countersigns 1,500 applications a year by researchers to the Home Office - and that he sends about 100 of them back for amendment before adding his ...
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    Collective phenomena: Absent Soviet friends (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 528-528 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Stockholm THE Sixth International Conference on Collective Phenomena last week cast light on the problem of scientific "refusniks" in the Soviet Union. Although many Western scientists have in the past ten years visited the regular Sunday seminars organized by the refusniks (Jewish scientists ...
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    Scientific publishing: Academic backs down on books (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 528-528 
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    Notes: [Auszug] EUROPEAN publishers were last week astounded by the announcement by Academic Press London (APL) that it is to make redundant more than half of its 247-strong workforce. The recent history of APL has been troubled (see Nature 303, 192; 1983) and changes were expected, but the scale of job losses ...
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    Factor VIII cloning (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 528-528 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] GENETICS Institute, the Cambridge (Massachusetts) biotechnology corporation, claimed last week important progress towards the production of factor VIII, the blood-clotting agent in which haemophiliacs are deficient. The institute says that it should have been able to clone and express the gene for ...
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    Creationism: Still in evidence in Texas (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 528-529 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] RELIGIOUS fundamentalists are shifting their efforts to local school boards, having largely failed in the courts and state legislatures to force the teaching of "creation science" in public schools. The current multiplicity of relatively low-key efforts seems, at least in some areas, to be paying ...
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    UK biotechnology: Where there's muck … (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 529-529 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ENCOURAGING signs of life in British biotechnology have been discovered by Biotechnology Investments Limited (BIL), the two-and-a-half-year-old company sponsored by the merchant bank N. M. Rothschild & Sons Limited. Since the end of May, when BIL's second annual report showed investments of ...
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    Numerology (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 530-530 
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    Notes: [Auszug] SIR - In the argument about numerology (Nature 7 July, p. 11 and 1 September, p.8), both the numerologists and their critics miss the point. Being impressed by the near match of numbers does not make science, nor is it scientific simply to stress the remaining inaccuracy and complain of the lack of ...
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    Yrast phenomena in fashion (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 531-531 
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    Notes: [Auszug] LEXICOGRAPHERS have been dismayed, but word-game players no doubt delighted, by the appearence on the scene of the word yrast, one of the rare contributions of the Swedish language to international usage. (The word is apparently the superlative of the adjective gr, which means "dizzy".) Its ...
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    Deep Sea Drilling Project: Sediment drifts and intraplate tectonics in the North Atlantic (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 532-533 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ON 17 August 1983, the GlomarChallenger docked in St. John's, Newfoundland, with more than two miles of sediment cored from a climatically critical region of the North Atlantic Ocean. This ended a voyage begun 55 days earlier in Norfolk, Virginia, that took the Challenger to a transect of six sites ...
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    International ethological conference: The evolutionary basis of behaviour (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 533-534 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN its early days, the science of ethology was devoted largely to the description of the behaviour patterns of animals. Today, however, the subject encompasses a wide range of disciplines, as indicated by the themes of the Plenary Sessions at the 18th International Ethological Conference*: ...
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    Molecular biology: Exons : present from the beginning? (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 535-537 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SINCE introns and exons were discovered six years ago, the split organization of eukaryotic genes has been seen as a mechanism for enhancing the rateof evolutionary change. First, Gilbert1 put forward the important hypothesis that exons correspond to protein functions which can be reshuffled by ...
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    Immunology: The I–J paradox remains unsolved (1983)
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    Nature 306 (1983), S. 537-538 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE I region of the mouse major histo-compatibility complex (H-2) codesfor cell surface glycoproteins referred to as class II molecules but previously known as I-region associated or Ia antigens. The class II molecules areheterodimers of two trans-membrane glycoproteins, a 32,000 molecular ...
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    Immunology: HLA class II antigens and monoclonal antibodies (1983)
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    Nature 306 (1983), S. 538-539 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] AT a recent workshop* in Edinburgh investigators from forty different laboratories grappled with the idiosyncratic properties of more than 100 monoclonal antibodies raised against HLA Class II antigens. These glycoproteins, also known as la antigens, are of great interest because of their ...
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    Immunology: Mitochondria and the major histocompatibility complex (1983)
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    Nature 306 (1983), S. 539-540 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two new papers appearing in Nature1,2 add those with an interest in mitochondria to the ever-growing list of scientists required to understand something of the major histocompatibility complex (MHC). Not so many years ago the MHC was commonly thought to be too complex to be comprehensible to all ...
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    Invertebrate endocrinology: Steroids…the earliest hormones (1983)
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    Nature 306 (1983), S. 540-540 
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    Notes: [Auszug] ECDYSTEROIDS, the hormones controlling development in arthropods and present in certain plant families, have now been found in helminth parasites of humans and livestock (trematodes1, filarial nematodes2 and cestodes3,4). As reported at a recent conference*, one result - of great potential ...
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    Hydrogen isotopic evidence of rhyolitic magma degassing during shallow intrusion and eruption (1983)
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    Nature 306 (1983), S. 541-545 
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    Notes: [Auszug] Deuterium and water contents of rhyolite obsidian tephra clasts and lava flows sampled in the western USA decrease within each eruptive sequence, from D- and H2O-rich, explosive (Plinian) eruptions, to D- and H2O-depleted lava flows. These changes result not from volatile ...
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    Formation of fossil hydrothermal chimneys and mounds from Silvermines, Ireland (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 545-550 
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    Notes: [Auszug] Sulphur isotope analyses reveal that the fossil hydrothermal pyrite mound and tubes at Silvermines were produced by the reaction of hydrothermal Fe(II) with bacteriogenically-reduced sulphur species (δ34S range:−18.4 to −42.5%). This took place in a brine pool ...
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    Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development (1983)
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    Nature 306 (1983), S. 551-557 
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    Notes: [Auszug] Nucleotide sequence and deletion analysis have been used to identify the regulatory and coding sequences comprising the cholera toxin operon (ctx). Incorporation of defined in vitro-generated ctx deletion mutations into Vibrio cholerae by in vivo genetic recombination produced strains which have ...
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    Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 557-561 
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    Notes: [Auszug] DNA sequences containing the 5′-flanking regions of the insulin and chymotrypsin genes were linked to the coding sequence of the chloramphenicol acetyltransferase (CAT) gene. The insulin gene recombinant elicits preferential expression of CAT activity when introduced into cells producing ...
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    Pure β -adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 562-566 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The β-adrenergic receptor binding subunits from frog erythrocytes, hamster lung and guinea pig lung have been purified to apparent homogeneity and in all cases reside on a single polypeptide. Insertion of the pure receptors into phospholipid vesicles and subsequent fusion of these vesicles ...
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    Radio discovery of a young supernova (1983)
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    Nature 306 (1983), S. 566-568 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We have three sets of observations on which the actual discovery7 of a radio supernova in NGC4258 is based: (1) a combination of data taken with the Westerbork Synthesis Radio Telescope (WSRT) in 1974-75 and data taken with the Very Large Array (VLA) in June 1979 at 1,415 and 1,480 MHz ...
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    CCD images of the 6.1 ms pulsar field (1983)
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    Nature 306 (1983), S. 568-569 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The short-period end of the pulsar distribution is dominated by the Crab and Vela pulsars: they are typical young objects with a vigorous energy output, and, because of their unique evolutionary status, have served as a basis for much of the theoretical debate on pulsars' emission mechanisms (see, ...
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    Actively transcribed genes are associated with the nuclear matrix (1983)
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    Nature 306 (1983), S. 607-609 
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    Notes: [Auszug] DNA attached to a protein matrix was isolated from hen oviducts and digested with the restriction enzyme EcoRI. The released (85% of total) and bound (15% of total) fractions were separated quantitatively and analysed by gel electrophoresis, blotted to nitrocellulose by the method of Southern13 and ...
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    Sequence of cDNA encoding human insulin-like growth factor I precursor (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 609-611 
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    Notes: [Auszug] For the isolation of IGF-I cDNA we used a cDNA library derived from human adult liver12. This library was constructed by preparing double-stranded cDNA from poly (A)-containing mRNA and inserting it into the Pstl restriction site of the pBR322 derivative pKT21813, using the dG-dC tailing technique. ...
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    Correlation between a DNA restriction fragment length polymorphism and C4A6 protein (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 615-616 
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    Notes: [Auszug] Genomic DNA was prepared from peripheral blood of individuals typed for C4 and samples were digested with various restriction endonucleases, the resulting fragments separated by agarose gel electrophoresis, transferred to nitrocellulose filters and hybridized with a 32P-labelled cDNA probe known to ...
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    Isolation and structural organization of the human preproenkephalin B gene (1983)
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    Nature 306 (1983), S. 611-614 
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    Notes: [Auszug] A human genomic DNA library22 was screened for phage carrying preproenkephalin B (alternatively designated prepro-dynorphin) gene sequences by hybridization in situ23 at 60 C with a porcine cDNA probe1. To examine whether the initial phage clones thus obtained carried the entire mRNA-coding ...
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    Plasmids of the same Inc groups in Enterobacteria before and after the medical use of antibiotics (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 616-617 
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    Notes: [Auszug] Among a collection of Enterobacteriaceae made by E. D. G. Murray between 1917 and 1954, 84 (19%) transferred conjugative plasmids to E. coli K-12. Of these, 36 determined colicinogeny, one determined tellurite resistance and 47 were cryptic1. We labelled cryptic conjugative plasmids with antibiotic ...
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    Diminished in vitro tyrosine kinase activity of the EGF receptor of senescent human fibroblasts (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 617-620 
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    Notes: [Auszug] We first related the ability of EGF to stimulate DNA synthesis with expression of EGF receptors by WI-38 cells of various in vitro ages. The in vitro age of WI-38 cultures was monitored using two indices, population doubling level (PDL)22 and per cent of the replicative lifespan completed (PLC)23; ...
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    Phosphorylation-dependent contraction of actomyosin gels from amphibian eggs (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 620-622 
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    Notes: [Auszug] Procedures used for preparation of high-speed cytoplasmic extracts (HSE) from Xenopus eggs are outlined in Fig. 1. When HSE is incubated at 18-25 C, a distinct gel forms which slowly contracts over a period of 12-24 h. Actin is a main component of the gel as shown by the following criteria: (1) a ...
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    Frank Yang and physics (1983)
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    Nature 306 (1983), S. 623-623 
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    Notes: [Auszug] WHEN distinguished physicists reach the age of sixty - or some similar milestone - it is not unusual to celebrate the occasion by bringing out a festschrift made up of papers written on request by friends and colleagues. These volumes must be a source of satisfaction to the person so honoured but ...
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    Low profiles (1983)
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    Nature 306 (1983), S. 623-624 
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    Notes: [Auszug] IN his Presidential Address to the Geochemical Society in 1976, Karl Turekian said "... one has the feeling that the whole field of trace metal marine geochemistry would have been a completely dull one over the past fifty years if it weren't for analytical errors! The startling conclusion, as the ...
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    Biology: the search for culture (1983)
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    Nature 306 (1983), S. 624-625 
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    Notes: [Auszug] EVOLUTIONARY theory is as attractive to biologists now as it has ever been. Most social scientists, however, continue to resist its allure, recalling the malign influence of nineteenth century evolutionism in the social arena. It is no surprise, then, that these two books on the relationship ...
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    Scattered thoughts (1983)
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    Nature 306 (1983), S. 625-625 
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    Notes: [Auszug] BLUE skies and red sunsets intrigued Leonardo de Vinci and stimulated some of the best scientific compositions of Tyndall and Lord Rayleigh. While no longer an enigma to a generation which was exposed to essays on sky colour in the classics of children's scientific literature and which witnessed ...
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    Anomalous science (1983)
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    Nature 306 (1983), S. 626-626 
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    Notes: [Auszug] FASCINATING insights into the evolution of nature's elements and the subsequent history of our Solar System can be obtained from the study of elemental abundances and isotopic anomalies in terrestrial, meteoritic and lunar materials. In this book, Paul Kuroda examines some of the facets of this ...
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    The rhythm of Barro Colorado (1983)
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    Nature 306 (1983), S. 625-626 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN 1980, T.C. Whitmore wrote: "The second half of the twentieth century will stand in history as the brief period during which Man reduced the area of the richest and most complex ecosystems in the world by one third". The ecosystems he referred to, of course, are the world's tropical rain forests ...
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    URL: http://dx.doi.org/10.1038/306625b0
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    Wild orchids (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 626-626 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] AT first sight this book appears to be all that English-speaking orchid enthusiasts have been waiting for - an authoritative up-to-date account of European orchids. Indeed, it is claimed to be so by the authors. The photographs are excellent but, unfortunately, the text does them scant justice as ...
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    URL: http://dx.doi.org/10.1038/306626b0
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    Where now on arms control? (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 411-412 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE Soviet Union's walk-out last week from the arms control negotiations at Geneva may not be quite the calamity that it seems: that is the bright side of the coin. For this development, well flagged in advance as the probable response to the first appearance in Europe of the cruise and Pershing II ...
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    URL: http://dx.doi.org/10.1038/306411a0
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    Wind blows cool (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 412-412 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Is the British Government's wind power programme in the doldrums? Earlier this year, the Department of Energy's advisory committee on research and development put wind at the top of the list of renewable sources of energy, saying at the same time that wave power is unlikely to be economic. As a ...
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    Spacelab project: West German involvement faces uncertain future (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 413-413 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE launch earlier this week from Cape Canaveral in Florida of the shuttle craft carrying the Spacelab experiment probably marks a turning point in collaboration on space projects between the European Space Agency (ESA) and the National Aeronautics and Space Administration (NASA) in the United ...
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    Max-Planck-Gesellschaft: Closer ties with universities (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 413-413 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE Max-Planck-Gesellschaft (MPG), West Germany's largest academic research organization outside the universities, will have a new president when Heinz Staab takes over from Reimar Lust in July 1984. The MPG has an annual budget of DM950 million (£240 million), of which 6 per cent comes from ...
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    Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 923-928 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Acquisition of invasive/metastatic potential through protease expression is an essential event in tumor progression. High levels of components of the plasminogen activation system, including urokinase, but paradoxically also its inhibitor, plasminogen activator inhibitor 1 (PAI1), have been ...
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    URL: http://dx.doi.org/10.1038/nm0898-923
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    T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 945-948 
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    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] B-cell activation depends on the intensity of B-cell receptor cross-linking. Studies of haptenated antigens1 and vesicular stomatitis virus2 (VSV) have demonstrated a correlation between antigen repetitiveness and the degree to which B-cell activation is independent of T cells. Here, we compare ...
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    URL: http://dx.doi.org/10.1038/nm0898-945
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    The Neurobiology of Suicide (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 973-973 
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    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] From the bench to the clinic (Annals of the New York Academy of Sciences, vol. 836) Edited by David M. Stoff & J. John Mann The New York Academy of Sciences, $80, 365 pp. ISBN1-57331 095-6, 1998 Reviewed By Angelo S. Halaris Department of Psychiatry, University of Mississippi, ...
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    Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 967-971 
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    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Ribozymes, catalytic RNA molecules that cleave a complementary mRNA sequence, have potential as therapeutics for dominantly inherited disease. Twelve percent of American patients with the blinding disease autosomal dominant retinitis pigmentosa (ADRP) carry a substitution of histidine for proline ...
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    The Genetics of Cancer (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 974-974 
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    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Genes associated with cancer Invasion, Metastasis and cell proliferation G.V. Sherbet & M.S. Lakshmi Academic Press, $85, 352 pp. ISBN: 0-126-39875-5, 1997 Reviewed By Daniel A. Haber Massachusetts General Hospital Cancer Center and Harvard Medical School,Charlestown, MA 02129 The ...
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    Erratum (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 974-974 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease Øyvind Molberc, Stephen N. Mcadam, Roman Korner, Hanne Quarsten, Christel Kristiansen, Lars Madsen, Lars Fuccer, Helce Scott, Ove Noren, Peter Roepstorff, Knut E.A. ...
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    Amyloid and Alzheimer disease (1998)
    [s.l.] : Nature Publishing Group
    Nature medicine 4 (1998), S. 745-745 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Over the last decade or so, the number of papers listed by the US National Library of Medicine with the word Alzheimer in their title has grown steadily—in all, some twelve thousand are listed. Yet despite this level of activity and the fact that this disease, thought to represent the most ...
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