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  • Process Engineering, Biotechnology, Nutrition Technology  (272)
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  • Articles  (272)
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  • 1980-1984  (272)
  • 1970-1974
  • 1925-1929
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  • 1984  (272)
  • 1972
  • 1983  (290)
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  • Process Engineering, Biotechnology, Nutrition Technology  (272)
  • Biology  (272)
  • 1
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    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 549-551 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] With a global market of $600 million predicted for mid-decade, industrial enzymes are an obvious target for biotechnology R&D. Exploiting recombinant DNA techniques and computer-aided molecular design systems, scientists hope to improve existing—indeed create new “custom ...
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    Nature biotechnology 2 (1984), S. 555-555 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although biotechnology is generally not a theoretical discipline, several researchers discussed important kinetic models. R. D. Tanner (Vanderbilt University, Tennessee) described use of non-constant parameters in the Monod model for growth kinetics. Dynamic phenomena such as hysteresis and ...
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  • 3
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    Nature biotechnology 2 (1984), S. 569-569 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] JULY MEETINGS July 16–20. UNESCO Sponsored Symposium on Biomass Conversion Technology: Principles & Practice. Waterloo, Ont., Canada. Info: M. Moo-Young, Institute for Biotechnology Research (E-l), University of Waterloo, Waterloo, Ont., Canada, N2L 3G1 July 18–20. Biochemical ...
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  • 4
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    Nature biotechnology 2 (1984), S. 385-387 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—The recent spate of recombinant DNA patent approvals and licensing efforts has both entrepreneurs and lawyers questioning the future of biotech intellectual property. The lingering doubts and controversy surrounding Stanford University's Cohen-Boyer patent (see next page) ...
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  • 5
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    Nature biotechnology 2 (1984), S. 398-403 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON, England—Monoclonal antibodies have begun to appear in consumer products. New pregnancy tests using a monoclonal antibody to the hormone human chorionic gonadotrophin (HCG) make it possible for women to find out if they are pregnant when their menstrual periods are only a day late. One ...
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  • 6
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    Nature biotechnology 2 (1984), S. 406-406 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON, England—The government is putting the finishing touches on a massive research program to entice British firms into investing in downstream processing. The program is part of the government's strategy to fill notable gaps in downstream processing skills in British industry. The ...
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  • 7
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    Nature biotechnology 2 (1984), S. 432-434 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Instrumentation will be the key to good scientific investigation, according to G. Pimentel (Univ. of California, Berkeley), who provided the keynote address for the New Frontiers in Chemistry symposium at the 35th Pittsburgh Conference on Analytical Chemistry held in Atlantic City, NJ in March. ...
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  • 8
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    Nature biotechnology 2 (1984), S. 441-444 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The problem of whey disposal or its meaningful utilization has plagued the dairy industry for many decades. In some countries, like Switzerland and Norway, where the art of cheese making in small plants still prevails, whey is disposed of locally by pig-feeding or by manufacture of whey cheese. ...
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  • 9
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    Nature biotechnology 2 (1984), S. 455-458 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] High frequency and reliable plant regeneration from somatic cells of Zea mays is the key step in allowing the tools of soma-clonal variation, somatic cell hybridization, and recombinant DNA to be used in the development of improved breeding lines. This communication describes high frequency plant ...
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  • 10
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    Nature biotechnology 2 (1984), S. 473-473 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Visiting Biotech 84 in London? Some of the stands and products worth seeing include: The micro-controlled Digital Dilute 9200 from Brinkmann Instruments functions as a diluter, dispenser, automatic pipette, sample distributor, and titrator. It comes equipped with two precision glass syringes (the ...
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  • 11
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    Nature biotechnology 2 (1984), S. 477-478 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Partners in the Research Enterprise: University-Corporate Relations in Science and Technology. Edited by Thomas W. Langfitt, Sheldon Hackney, Alfred P. Fishman, and Albert V. Glowasky. Pp. 175. ISBN 0-8122-1150-2 (U. of Pennsylvania Press, Philadelphia: 1983) $35.00 (hardbound), ...
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  • 12
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    Nature biotechnology 2 (1984), S. 479-479 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MEETINGS June 3–7. Tissue Culture Association (35th Annual Meeting). Houston, TX. Info: James R. Florini, Biology Dept., Syracuse University, 108 College Place, Syracuse, NY 13210 June 7–10. Fourth International Symposium on Rapid Methods and Automation in Microbiology and Immunology. ...
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  • 13
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    Nature biotechnology 2 (1984), S. 291-292 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BONN, West Germany—Biotechnology is at last taking root in West Germany. Academics are coming to see biology as an industrial activity, while the big industrial combines increasingly seek collaborative partnerships with centers of excellence in their own country. Government spending on ...
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  • 14
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    Nature biotechnology 2 (1984), S. 292-296 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] HAMBURG, West Germany—Despite their government's declared commitment to biotechnology (See page 291), German scientists who would like to be commercial biotechnologists have found the road to starting a company strewn with obstacles. Take Biosyntech, for example. Hubert Koester of the ...
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  • 15
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    Nature biotechnology 2 (1984), S. 303-303 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—Although the road to becoming chief executive of a biotech start-up company can be long and indirect, a recent informal survey reveals that a surprising number of these CEOs have put in time at one place: Baxter Travenol Laboratories (Deerfield, IL). Baxter alumni that ...
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  • 16
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    Nature biotechnology 2 (1984), S. 327-332 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Trade in biotechnology products is just beginning as the products start to reach the international marketplace. Even firms not planning to manufacture and market specific products should consider foreign markets for biotechnology products, and the Japanese market certainly will be a key factor in ...
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  • 17
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    Nature biotechnology 2 (1984), S. 342-342 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Regulatory Affairs Professional Society (RAPS), an organization for regulatory affairs officers from the chemical, pharmaceutical, and medical device industries, sponsored an educational seminar titled “Biotechnology: The Regulatory Revolution” late last year. The seminar focused on ...
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  • 18
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    Nature biotechnology 2 (1984), S. 361-363 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] April brings the Federations of American Societies for Experimental Biology's (FASEB) annual meeting. A great variety of manufacturers will exhibit their wares at the meeting, and many of the products that will be on display are featured below. In addition, a range of fermentation products are ...
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  • 19
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    Nature biotechnology 2 (1984), S. 364-366 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Alcohol Fuels: Options for Developing Countries. Report of an ad hoc panel of the Advisory Committee on Technology Innovation, Board of Science and Technology for International Development. Pp. 109. ISBN 0-309-03386-1 (National Academy Press, Washington, D.C.: 1983). $8.95 The current ...
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  • 20
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    Nature biotechnology 2 (1984), S. 200-200 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Readers may benefit themselves and their fields if they consider several imperatives for US biotechnology over the coming year. •Environmental concerns, particularly issues regarding the microbial fitness of future products and known, wild-type pathogens, should be elevated to become strong ...
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  • 21
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    Nature biotechnology 2 (1984), S. 204-207 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.–Legal action against the Recombinant DNA Advisory Committee (RAC) has once again delayed the plans of Advanced Genetic Sciences (AGS) for moving ahead with field testing the genetically engineered strain of Pseudomonas syringae that the company hopes will prevent frost damage ...
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  • 22
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    Nature biotechnology 2 (1984), S. 214-228 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Top: Photomicrograph of recombinant alpha-A interferon crystals. Bottom: Record from clinical trial of Hoffmann-La Roche's recombinant alpha-A interferon, showing a patient's blood levels of interferon. This is a time of decision about interferon, the collective name for one group of substances ...
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  • 23
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    Nature biotechnology 2 (1984), S. 254-259 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Bacillus megaterium has been used industrially to produce vitamins, amino acids and proteins. Recently, our laboratory isolated a generalized transducing bacteriophage for this species, and several loci have been mapped. To further study strain QM B1551, we have now analyzed its resident plasmids ...
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  • 24
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    Nature biotechnology 2 (1984), S. 259-263 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A strain of Escherichia coli that leaks cellulase activity encoded by cloned cellulase genes from Cellulomonas fimi was isolated following mutagenesis with nitrosoguani-dine. The strain also leaks several other normally periplasmic enzymes into the culture medium: β-lactamase, alkaline ...
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    Nature biotechnology 2 (1984), S. 110-110 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Perhaps the most valuable bequest Selman Waks-man left to future generations of microbiologists was an enthusiasm for studying mixed populations of organisms as they occur naturally, in addition to the highly artificial pure cultures usually prepared for laboratory investigation. It was ecological ...
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    Nature biotechnology 2 (1984), S. 116-117 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LOS ANGELES, California—Researchers at the University of Southern California School of Dentistry here have cloned the first dental gene, important in tooth enamel formation. They envision a day when the protein components of human enamel can be made into a pastelike mixture to replace the ...
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    Nature biotechnology 2 (1984), S. 124-124 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Price Dec. 15 Price Jan. 15 Percent Change 52 Week Hi-Low Market Capitalization in $ millions (stock price × number of shares outstanding) Companies Emphasizing Recombinant DNA Technology Advanced Genetic Sciences 7 9 +29 14¾–6¼ 98 ...
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    Nature biotechnology 2 (1984), S. 138-142 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Legal protection for the intellectual property of industrial and academic genetic engineering laboratories has acquired paramount importance in the last few years. Traditionally, there have been three basic forms of protection: patents, trade secrets, and private contracts. One or more of these, ...
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    Nature biotechnology 2 (1984), S. 146-147 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A conference titled The Use of Liposomes in Medicine, held in honor of Brenda E. Ryman on her retirement from Charing Cross Hospital Medical School (London, U.K.), offered a forum for liposome researchers to present their latest results, but it also provided a fitting occasion to reflect on the ...
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    Nature biotechnology 2 (1984), S. 173-174 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Gene Age. By Edward J. Sylvester and Lynn C. Klotz. Pp. 208. ISBN 0-684-17950-4 (Charles Scribner's Sons, New York: 1983) $14.95. The Gene Age is an excellent one-stop review of the controversies and some of the promises brought on by the advent of genetic engineering. The text is ...
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    Nature biotechnology 2 (1984), S. 180-181 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Feb. 13–16. Structure and Expression of Eukaryotic Genomes. Victoria, Australia. Info: G. Miklos, Research School of Biological Sciences, Australian National University, GPO Box 4, Canberra City, 2601, Australia Feb. 19–23. 28th Annual Meeting of the Biophysical Society. San Antonio, ...
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    Nature biotechnology 2 (1984), S. 182-183 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Title: Genes and DNA Transfer Vectors for Prorelaxin Expression Inventors: P. J. Hudson, J. D. Haley, H. D. Niall, and J. Shine, Australia Assignee: Howard-Florey Institute of Experimental Physiology and Medicine, Australia Filing and Issue Data EPO Patent No.: 86-649 Publication Date: 24 ...
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    Nature biotechnology 2 (1984), S. 1005-1005 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: In their article (BIO/TECHNOLOGY 2:805, 1984) entitled “Chemical and Bacterial Pretreatment of Lignocellulosic Material to Increase Ruminant Digestibility,” Drs. Kerr, Windham, and Benner report that pretreatment with nitric acid is the method of choice for increasing ...
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    Nature biotechnology 2 (1984), S. 1005-1005 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] To the editor: Dr. James Murray's response to Damon Corporation's vice president of public information, Marcia A. Kean (BIO/TECHNOLOGY 2:733, 1984), leaves me wondering whether his scholarly distinction between Damon Biotech and de novo biotech companies is unnecessary hair splitting. Was not ...
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    Nature biotechnology 2 (1984), S. 1005-1005 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] To the editor: I am writing in reference to your article entitled “Phillips: Wildcatting in Biotech” (BIO/TECHNOLOGY 2:853, 1984). The article implied that the Bartlesville Energy Technology Center (BETC), including its capabilities in microbial enhanced oil recovery, is now defunct. I ...
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    Nature biotechnology 2 (1984), S. 1011-1012 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] ROCKVILLE, Md.—Two new companies are seeking to commercialize 2-dimensional gel electrophoresis, a separations technology that has existed for close to a decade. Bioresources Laboratories, the for-profit company started here by the American Type Culture Collection (ATCC) a year-and-a-half ...
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    Nature biotechnology 2 (1984), S. 1016-1016 
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    Notes: [Auszug] TORONTO, Ont.—The Canadian Environmental Law Research Foundation (CELRF) has proposed creation of a National Biotechnology Commission to study, assess, and certify all new life forms intended for release into the environment. Such a commission would also administer a nationwide information ...
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    Nature biotechnology 2 (1984), S. 1021-1021 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] New joint ventures continue to be the rage in biotechnology: • Celltech (Slough, U.K.) has set up its second joint venture company, this one a 50:50 owned project with Air Products Ltd., to be called Apcel. The firm, originally capitalized with £3.2 million , will apply genetic ...
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    Nature biotechnology 2 (1984), S. 1029-1033 
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    Notes: [Auszug] Make-or-buy is a common and crucial dilemma facing corporate planners throughout the high technology industries—is it better to solve an R&D problem in-house or would it be more economical to deal with it through a joint venture or contract research? While executives are often inherently ...
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    Nature biotechnology 2 (1984), S. 1058-1062 
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    Notes: [Auszug] A method of production of human tissular plasminogen activator (H t-PA) using human embryonic lung (HEL) cells that are devoid of “transforming growth factors” (TGFs) is described. Basal levels of H t-PA in serum-free medium were increased about four times using concanavalin A (Con A) ...
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    Nature biotechnology 2 (1984), S. 1085-1088 
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    Notes: [Auszug] A new recirculating isoelectric focusing system for separation of proteins has been introduced by Ionics, Inc. (Watertown, MA). The 10-channel focusing chamber of the Iso-Prep™ System has an effective area of 10 cm2. Typical throughput is about 2 g of protein in 1–2 hours. Write in 600 ...
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    Nature biotechnology 2 (1984), S. 1089-1089 
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    Notes: [Auszug] JANUARY MEETINGS Jan. 26–Feb. 2. UCLA Symposium on Monoclonal Antibodies and Cancer Therapy. Park City, UT. Info: Betty Handy, Program Coordinator, UCLA Symposia, Molecular Biology Institute, University of California, Los Angeles, CA 90024 Jan. 28–Feb. 1. 9th Annual Symposium on ...
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    Nature biotechnology 2 (1984), S. 1000-1000 
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    Notes: [Auszug] As biotechnology enters the marketplace, it leaves the relatively cloistered environment of the research laboratory and comes into full contact with society. The future of this promising area of enterprise will be determined by the ability of the industry to come to terms with this collision of ...
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    Nature biotechnology 2 (1984), S. 928-928 
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    Notes: [Auszug] PHILADELPHIA—Plant and animal cells—in addition to microorganisms—grow to extremely high concentrations in the Bio Reactor, a novel fermenter that incorporates a spin-flow filter. Developed at Arthur D. Little (Cambridge, MA), the Bio Reactor's configuration permits continuous ...
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    Nature biotechnology 2 (1984), S. 933-933 
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    Notes: [Auszug] LONDON—Two British companies are developing a commercial biotechnology process to produce a novel human food. Ranks Hovis McDougall (RHM), the milling, bakery, and animal feedstuff's group, has joined forces with Imperial Chemical Industries PLC (ICI) to scale up and test-market meat products ...
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    Nature biotechnology 2 (1984), S. 939-944 
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    Notes: [Auszug] Are herbicide-tolerant varieties of crop plants produced through genetic engineering, tissue culture, and conventional breeding anything. more than demonstrations of feasible biotech nology? Most major crops are already tolerant to herbicides that address their associated weed spectra, so many ...
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    Nature biotechnology 2 (1984), S. 967-978 
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    Notes: [Auszug] Only some prokaryotes have evolved the genetic information for nitrogen fixation. These prokaryotes, when associated with plants, can contribute to their growth by providing reduced nitrogen (ammonia). The genetics of nitrogen fixation was elucidated in Klebsietta pneumoniae, where it was found ...
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    Nature biotechnology 2 (1984), S. 839-839 
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    Notes: [Auszug] Biotechnology's highlights reflected through the popular media (cloning and gene splicing, interferons and monoclonals, nitrogen-fixing cereals and the conquest of hereditary disease) are undoubtedly important. With the benefit of hindsight, however, even researchers deeply involved in these fields ...
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    Nature biotechnology 2 (1984), S. 875-883 
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    Notes: [Auszug] Many of the physical and chemical parameters which influence the behavior of a microorganism are changed as the scale of operation is changed. A description is given of how the most important of these effect process performance. As well as opening up new doors for novel process control techniques, ...
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    Nature biotechnology 2 (1984), S. 861-867 
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    Notes: [Auszug] Israel is pursuing an ambitious biotechnology development program that encompasses pharmaceuticals, food production, waste recycling, oil recovery, and, above all, horticulture and plant agriculture. With support from government and unique cooperation among companies, universities, and kibbutzim ...
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    Nature biotechnology 2 (1984), S. 912-912 
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    Notes: [Auszug] There's a truism: if it works, don't fix it. Or, if you're winning a race, don't shoot yourself in the foot. Yet that is precisely what the United States seems to be doing in biotechnology. The popular media frequently enthuse about the “miracles” of biotechnology. But the wonderful ...
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    Nature biotechnology 2 (1984), S. 10-12 
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    Notes: [Auszug] WASHINGTON, D.C.—U.S. bio-technologists are initiating a public education campaign, prompted partly by what they see as harmful publicity in the past few months. The publicity has stemmed mostly from legal moves that challenge National Institutes of Health (NIH) procedures for overseeing ...
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    Nature biotechnology 2 (1984), S. 104-104 
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    Notes: [Auszug] In the early part of the eighteenth century, the British Government gave The South Sea Company a monopoly over British trade in the South Seas. British investors believed that great riches were to be had from such trade. Further rumors were circulated that England was to be given the right of free ...
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    Nature biotechnology 2 (1984), S. 61-61 
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    Notes: [Auszug] To the editor: Your August article on the forth coming Office of Technology As sessment report did well in summa rizing in a brief space a document which could be as important as the OTA's earlier work on the impact of applied genetics. But one point might be amplified: the role of ...
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    Nature biotechnology 2 (1984), S. 7-7 
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    Notes: [Auszug] President Reagan's trip to Japan in the late fall of last year came at a time of heightened tension between the U.S. and its strongest Far Eastern ally, a tension generated in part by Japan's phenomenal success in competing in two industrial areas that were formerly American strongholds: ...
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    Nature biotechnology 2 (1984), S. 73-76 
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    Notes: [Auszug] T1-plants (first generation of transformed plants) regenerated from hairy root culture lines synthesized the same opines and carried T-DNA with the same restriction pattern as the parental line. Opine synthesis segregated in the progeny of T1-plants (T2-plants), Two opine-positive T2-plants had ...
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    Nature biotechnology 2 (1984), S. 76-81 
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    Notes: [Auszug] Recombinant DNA technology was used to produce human urogastrone with a C-terminal polyarginine fusion. This peptide fusion formed the basis of a two-step ion exchange purification that gave 64mg of urogastrone at 〉95% purity with 44% yield. In the first step, a substantial purification was ...
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    Nature biotechnology 2 (1984), S. 86-87 
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    Notes: [Auszug] Methods in Enzymology Volumes 100 and 101; Recombinant DNA Parts B and C. S. P. Colowick S P, R. Wu R. Pp. 540. ISBN 012-182-000-9 (Academic Press, Inc. Publishers, New York, NY: 1983) $69.50. Books entitled “Recombinant DNA” have received considerable interest lately. ...
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    Nature biotechnology 2 (1984), S. 733-733 
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    Notes: [Auszug] To the editor: In the July 1984 issue (p. 619), the article entitled “Initial Public Offerings of Biotechnology Companies 1980–1983” states, “Damon Biotech was excluded from further analysis because the amount of true pre-public investment was not disclosed by the ...
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    Nature biotechnology 2 (1984), S. 733-733 
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    Notes: [Auszug] The article concerning IPOs was an attempt to apply econometric/statistical methods to the actual experience of biotechnology companies in “going public. ” Thereby, I hoped to establish a “reality”-oriented understanding as opposed to the oft heard bio-hype. The assumptions ...
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    Nature biotechnology 2 (1984), S. 733-733 
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    Notes: [Auszug] To the editor: In his review (BIO/TECHNOLOGY 2:566; 1984) of our published report, Biobusiness World Data Base, Cetus chairman Ronald E. Cape poses several objections. Paradoxically, he himself proceeds to refute them in the course of his critique. As the editor who redded and released this ...
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    Nature biotechnology 2 (1984), S. 733-734 
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    Notes: [Auszug] To the editor: The VIIIth International Biotechnology Symposium took place in New Delhi, India, from February 19 to 25, 1984, with the slogan “Biotechnology—The Obvious Answer. ” Unfortunately, it wasn't the obvious answer for Israeli scientists—or for me, for I decided at ...
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    Nature biotechnology 2 (1984), S. 734-734 
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    Notes: [Auszug] To the editor: Your June editorial, “A Little Secrecy Goes a Long Way, ” raised some interesting and pertinent issues for which the writer, Arthur Klausner, is to be commended. However, his assertion that companies such as Immunex release information to “hype” their stock ...
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    Nature biotechnology 2 (1984), S. 737-737 
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    Notes: [Auszug] Several things about the recent discussions of “biotechnology transfer” have disturbed us. All the talk of late has been of things, not of people, of tools, not of the craft of using them. Both elements, the human and the material, are vital to any technology. Yet biotechnology, tied so ...
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    Nature biotechnology 2 (1984), S. 739-739 
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    Notes: [Auszug] On the morning of July 1, in Leningrad, Soviet RGB agents detained Ephraim Katchalski-Kat-zir. Dr. Katzir was in the Soviet Union as the guest of Academician Yu. A. Ovchinnikov, vice president of the U.S.S.R. Academy of Sciences and director of the M. M. Shemyakin Institute of Bio-organic ...
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    Nature biotechnology 2 (1984), S. 740-740 
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    Notes: [Auszug] Rice, cultivated in paddy fields as the staple daily food for millions of people in South East Asia, is a remarkable crop. It provides about the same share of the earth's cereal production as do wheat and maize (corn), which are much more familiar to Westerners. Indeed, it exceeds wheat in yield ...
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    Nature biotechnology 2 (1984), S. 743-747 
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    Notes: [Auszug] BALTIMORE, Maryland—Johns Hopkins University researchers have applied for a patent on a new and more efficient way of making hybridomas, the hybrid cells that produce monoclonal antibodies. Nova Pharmaceutical Corp. (Morristown, NJ) has acquired the worldwide rights to the technology, taking ...
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    Nature biotechnology 2 (1984), S. 749-750 
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    Notes: [Auszug] NEW YORK—Scientists and specialists on Soviet technology are questioning—and sometimes denouncing—the data and conclusions of an influential Wall Street Journal series on Soviet research on biological weapons. William Kucewicz, in his eight-part editorial series, “Beyond ...
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    Nature biotechnology 2 (1984), S. 750-750 
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    Notes: [Auszug] Japan's Ministry of International Trade and Industry has compiled a report on promoting bio-industry. It emphasizes personnel training and establishing biotech research conferences and information centers. The U.S. Department of Agriculture formed a Plant Gene Expression Center in Berkeley, CA. ...
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    Nature biotechnology 2 (1984), S. 753-755 
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    Notes: [Auszug] NEW YORK—Are simple unicellular organisms—bacteria and yeast—the best systems for manufacturing complex mammalian proteins? Many researchers think not, and are turning to a more “natural” source, cultured animal cells. Mammalian cells can synthesize and correctly ...
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    Nature biotechnology 2 (1984), S. 757-757 
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    Notes: [Auszug] LOUISVILLE, KY—A researcher here thinks he may have a way to save face—save the faces of weathered marble statues, that is. K. Lal Gauri, chairman of the geology department at the University of Louisville, hopes microbes can be used to chemically convert the black gypsum crust that ...
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    Nature biotechnology 2 (1984), S. 759-761 
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    Notes: [Auszug] NEW YORK—Studies specifically designed toward identifying U.S. biotechnology personnel are proliferating. Traditional surveys on scientific employment patterns fail to single out and highlight biotechnologists, a category spanning many disciplines and industries. At least three studies, ...
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    Nature biotechnology 2 (1984), S. 763-772 
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    Notes: [Auszug] Forestry researchers have a favorite New Yorker cartoon they like to include in their slide shows at meetings. The cartoon depicts a pompous, prosperous-looking man strolling through the woods with a small boy. “It's good to know about trees, ” he is saying. “Just remember nobody ...
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    Nature biotechnology 2 (1984), S. 774-775 
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    Notes: [Auszug] One barometer of a developing industry is the quantity and quality of the start-up firms it spawns. The technologies and markets addressed by nascent biotech operations often indicate the business opportunities that entrepreneurs perceive. These can exist either because of technological advances, ...
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    Nature biotechnology 2 (1984), S. 777-781 
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    Notes: [Auszug] When living cells are used to produce valuable biologicals there is an optimal time for product recovery. It is therefore important to monitor product concentration during the fermentation or cell growth cycle. Fast protein liquid chromatography (FPLC) is a convenient method for measuring proteins ...
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    Nature biotechnology 2 (1984), S. 783-784 
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    Notes: [Auszug] Recent R&D in fields ranging from thermal/chemical processing of biomass to applied microbial research to bioprocess monitoring and control systems provided the highlights of the Sixth Symposium on Biotechnology for Fuels and Chemicals, held 15–18 May in Gatljnburg, Tennessee. The ...
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    Nature biotechnology 2 (1984), S. 786-788 
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    Notes: [Auszug] The field of analytical methods in biotechnology is expanding rapidly. Applications range from integrating conventional analytical techniques—high performance liquid chromatography (HPLC), gel/liquid chromatography (GLC), mass spectrometry (MS), nuclear magnetic resonance (NMR), ...
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    Nature biotechnology 2 (1984), S. 788-788 
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    Notes: [Auszug] Several interesting developments in Soviet biotechnology have been published recently. The All Union Scientific Research Institute of Bioengineering in Moscow has developed an experimental computerized information system called “Ellips-Mikrobiologiiya.” A recent report1 claimed the ...
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    Nature biotechnology 2 (1984), S. 791-795 
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    Notes: [Auszug] RNA secondary structure can be most simply visualized on the basis of runs of complementary bases in the primary sequence. These complementary regions predict an ability of a molecule to fold back on itself to form double stranded helical regions. Computer methods which utilize energy rules to ...
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    Nature biotechnology 2 (1984), S. 796-799 
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    Notes: [Auszug] Antibiotic TA adheres avidly to a variety of surfaces. When administered orally or intravenously to animals, the antibiotic concentrates in an active form close to the site of administration. No measurable blood level of the antibiotic is found. Tissues treated with antibiotic TA and then washed ...
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    Nature biotechnology 2 (1984), S. 800-804 
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    Notes: [Auszug] Recombinant calf prochymosin synthesized in E. coli was shown to accumulate in the form of insoluble inclusion bodies. Isolation of this aggregated material, combined with specific washing procedures, was the most significant stage of the purification protocol. Disruption of proteins in the ...
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    Nature biotechnology 2 (1984), S. 805-807 
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    Notes: [Auszug] A variety of chemical treatments was examined for the ability to decrease the relative lignin content and increase the in vitro dry matter digestibility of peanut hulls. Of these chemical treatments, nitric acid was the most successful at removing lignin; however, none of the chemical treatments ...
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    Notes: [Auszug] The multi-copy plasmid vector pIJ702 has been used to clone Streptomyces clavuligerus chromosomal DNA fragments into a clavulanic acid non-producing mutant strain. Two DNA segments, which restored the ability to synthesise clavulanic acid, were shown to overlap one another and share a common ...
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    Nature biotechnology 2 (1984), S. 813-819 
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    Notes: [Auszug] Ionics, Inc. (Watertown, MA) introduces a recirculating isoelectric focusing system called IsoPrep™. It separates proteins of differing pis on a preparative scale under applied electrical potential. The system's membranes permit convection but let proteins migrate freely until they reach a ...
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    Nature biotechnology 2 (1984), S. 821-821 
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    Notes: [Auszug] The Fundamentals of Nitrogen Fixation. J. R. Postgate. Pp. 252. ISBN 0-521-24169-3. (Cambridge University Press, Cambridge, England: 1982) $37.50. This modestly-sized volume reminds me favorably of Harris' Nucleus and Cytoplasm, a small but influential book from my past. Like its ...
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    Nature biotechnology 2 (1984), S. 823-823 
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    Notes: [Auszug] OCTOBER MEETINGS Oct. 10–11. Robert S. First Conference: The New Microbiology. Washington, B.C. Info: Robert S. First, 707 Westchester Avenue, White Plains, NY 10604 Oct. 11. Today's Profit Opportunities in Biotechnology. Philadelphia, PA. (Also Nov. 15 in Houston, TX.) Info: Consulting ...
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    Nature biotechnology 2 (1984), S. 832-832 
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    Notes: [Auszug] Jeremy Rifkin is the most vocal and, to date, the most publicized critic of genetic engineering and its application. At his behest, the courts have issued an injunction against the deliberate release of a genetically engineered organism. The implications of this ruling are not yet be entirely ...
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    Nature biotechnology 2 (1984), S. 663-663 
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    Notes: [Auszug] Some debates are perpetual: If information is scarce or ambiguous, then the debaters argue interminably from first principles and present their surmises as proven fact. Or they confuse what is true with what is right, and impassioned partisanship replaces understanding. Public discussions of ...
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    Nature biotechnology 2 (1984), S. 665-665 
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    Notes: [Auszug] “Single cell protein J polyhydroxybutyrate not the end of the story.” That forecast was made two years ago by Eric Howells from Id's Corporate Research and Technology Department. The real “end of the story”, he suggested, was the use of stable, safe, versatile microorganisms ...
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    Nature biotechnology 2 (1984), S. 667-668 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—A small British biotechnology company specializing in continuous fermentation is developing a process for making Protein A, a unique bacterial molecule with vast potential for therapy and immuno-diagnostics. If successful, this could pave the way for converting other batch processes ...
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    Nature biotechnology 2 (1984), S. 671-671 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW ORLEANS—Imreg, a 31/2-year-old, newly public biotechnology company here, is rewriting the book on industry-university relations. Its founder and president, A. Arthur Gottlieb, also serves as professor and chairman of the department of microbiology and immunology at the Tulane University ...
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  • 92
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    Nature biotechnology 2 (1984), S. 672-672 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Agreements between biotechnology companies and universities have some unique characteristics when compared to other disciplines, but do not represent a grave threat to academic integrity. This is the conclusion of a report titled The Science Business, published this summer by the ...
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    Nature biotechnology 2 (1984), S. 672-672 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] REHOVOT, Israel—Inter-Yeda, an Israeli pharmaceutical company that has strong research links with the Weizmann Institute of Science, has just launched the first interferon-containing medication approved for commercial distribution outside the socialist bloc. The new preparation, PRONE, ...
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    Nature biotechnology 2 (1984), S. 673-673 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] EAST LANSING, MI—With its permanent director now in place, the three-year-old Michigan Biotechnology Institute (MB I) is gearing up for activity. MBI, which has $6 million assured in state support and hopes to garner additional private and institutional funding, will study the ways ...
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  • 95
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    Nature biotechnology 2 (1984), S. 674-675 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—Barking instructions into the telephone about his latest $50–100 million venture capital fund, Frederick R. Adler seems at home in his office. After a double hip replacement last summer and some soul-searching about what he wanted out of life, the feisty ...
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    Nature biotechnology 2 (1984), S. 672-672 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MOSCOW—The Soviet media coverage of this year's “Chemical Workers' Day” (one of the many such annual festivals established to replace the old Saints' Days) this year paid special attention to the Ail-Union Institute of Genetics and Industrial Microorganism Selection. Achievements ...
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    Nature biotechnology 2 (1984), S. 676-680 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A year ago, everyone in biotech seemed to feel that even the phrase “research and development limited partnership” was full of excitement. A way for wealthy investors to participate in potentially revolutionary and lucrative discoveries, this funding vehicle came fully equipped with tax ...
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    Nature biotechnology 2 (1984), S. 682-684 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although the recent discovery of two retroviruses closely linked to acquired immunodeficiency syndrome (AIDS) is a major step in tracing— and therefore controlling—the epidemiology of this disease, it offers scant hope for AIDS victims. Discovery of a causative agent rarely begets an ...
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    Nature biotechnology 2 (1984), S. 686-692 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Glavmikrobioprom (Ministry of Microbiology Industry) or its successor will probably direct the industrialization of results from Soviet R&D in biotechnology. This body has been developing and producing substances to improve Soviet agriculture: Glavmikrobioprom enterprises have supplied feed ...
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    Nature biotechnology 2 (1984), S. 693-693 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Delegates to Biotech 84 Europe were greeted at London's Wembly Conference Center by a 50 foot long, 10 foot high fermentor parked on the bit of lawn just in front of the doors— hardly large enough to contain the ideas and interests to be processed inside. Kenneth Baker (Minister of State for ...
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