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  • General Chemistry  (1,822)
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  • BIOSCIENCES  (727)
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  • 1970-1974  (4,180)
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  • 1
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    In:  CASI
    Publication Date: 2005-11-30
    Description: The physical correlations of hearing, i.e. the acoustic stimuli, are reported. The auditory system, consisting of external ear, middle ear, inner ear, organ of Corti, basilar membrane, hair cells, inner hair cells, outer hair cells, innervation of hair cells, and transducer mechanisms, is discussed. Both conductive and sensorineural hearing losses are also examined.
    Keywords: BIOSCIENCES
    Type: BioTechnol., Inc. Bioastronaut. Data Book, 2d Ed.; p 667-691
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  • 2
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    In:  CASI
    Publication Date: 2005-11-30
    Description: Oxygen toxicity is examined, including the effects of oxygen partial pressure variations on toxicity and oxygen effects on ozone and nitrogen dioxide toxicity. Toxicity of fuels and oxidizers, such as hydrazines, are reported. Carbon monoxide, spacecraft threshold limit values, emergency exposure limits, spacecraft contaminants, and water quality standards for space missions are briefly summarized.
    Keywords: BIOSCIENCES
    Type: BioTechnol., Inc. Bioastronaut. Data Book, 2d Ed.; p 455-487
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  • 3
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    In:  CASI
    Publication Date: 2005-11-27
    Description: Subjects on planetary flight missions, supporting technology, microbial release probabilities, heat sterilization cycles
    Keywords: BIOSCIENCES
    Type: NNING, EVALUATION, AND ANAL. STUDIES IN PLANETARY QUARANTINE AND SPACECRAFT STERILIZATION 15 JUN. 1970 (SEE N70-35042 19-04) 19-04/
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  • 4
    Publication Date: 2005-11-27
    Description: Conflicting sensory data relating to spatial orientation from visual, vestibular, and somatosensory systems inducing motion sickness
    Keywords: BIOSCIENCES
    Type: SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 45-52
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  • 5
    Publication Date: 2005-11-27
    Description: Mathematical model for short-term adaptation to vestibular stimuli in relation to angular velocity of nystagmus and angular velocity of head rotation
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 369-393
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  • 6
    Publication Date: 2005-11-27
    Description: Design criteria for onboard centrifuges in orbital space stations to create artificial gravity
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 329-346
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  • 7
    Publication Date: 2005-11-27
    Description: Linear acceleration effects on semicircular canals in elasmobranch fishes
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 159-166
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  • 8
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    In:  CASI
    Publication Date: 2005-11-27
    Description: Neurological elements in vomiting sequence and components of emetic reflex in motion sickness
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 117-120
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  • 9
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    In:  CASI
    Publication Date: 2005-11-30
    Description: The end organs, central nervous system connections, and static and dynamic characteristics of the vestibular system are presented. Vestibular servation in man and vestibular side effect prevention from space missions involving artificial gravity generation are also considered. Vestibular models and design criteria for rotating space vehicles are appended.
    Keywords: BIOSCIENCES
    Type: BioTechnol., Inc. Bioastronaut. Data Book, 2d Ed.; p 533-609
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  • 10
    Publication Date: 2005-11-27
    Description: Dynamic response of semicircular canals to constant rotation in linear acceleration field
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 353-362
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  • 11
    Publication Date: 2005-11-27
    Description: Extralabyrinthine influences as secondary etiological factors in susceptibility to motion sickness
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 83-88
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  • 12
    Publication Date: 2005-11-27
    Description: Linear acceleration movements as eliciting mechanism of motion sickness
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 7-28
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  • 13
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    In:  CASI
    Publication Date: 2005-11-27
    Description: Energy requirements for walking in simulated lunar gravity
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 347-352
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  • 14
    Publication Date: 2005-11-27
    Description: Experimental and clinical treatment of Meniere's disease using ultrasonic radiation
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 269-284
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  • 15
    Publication Date: 2005-11-27
    Description: Postsynaptic effects of vestibular and cerebellar impulses in vestibular nuclei neurons of cat
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 183-200
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  • 16
    Publication Date: 2005-11-27
    Description: Computer analysis of single-unit discharges in vestibular nerve of frog
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 137-144
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  • 17
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    In:  CASI
    Publication Date: 2005-11-27
    Description: Inadequate and inappropriate vascular and circulatory responses as causative factors in motion sickness
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 89-98
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  • 18
    Publication Date: 2005-11-27
    Description: Otolith organs as primary etiological factor in motion sickness
    Keywords: BIOSCIENCES
    Type: SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 53-66
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  • 19
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    In:  CASI
    Publication Date: 2005-11-27
    Description: Life support systems and space suits for preserving homeostatic reactions of astronauts
    Keywords: BIOSCIENCES
    Type: TRANS. OF THE FIRST LECTURES DEDICATED'TO THE DEVELOP. OF THE SCI. HERITAGE OF K. E. TSIOLKOUSKIY APR. 1970; P 91-98
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  • 20
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    In:  CASI
    Publication Date: 2005-11-30
    Description: Some data on human vision, important in present and projected space activities, are presented. Visual environment and performance and structure of the visual system are also considered. Visual perception during stress is included.
    Keywords: BIOSCIENCES
    Type: BioTechnol., Inc. Bioastronaut. Data Book, 2d Ed.; p 611-665
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  • 21
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    In:  CASI
    Publication Date: 2005-11-30
    Description: The general anatomy and function of the human respiratory system is summarized. Breathing movements, control of breathing, lung volumes and capacities, mechanical relations, and factors relevant to respiratory support and equipment design are discussed.
    Keywords: BIOSCIENCES
    Type: BioTechnol., Inc. Bioastronaut. Data Book, 2d Ed.; p 489-531
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  • 22
    Publication Date: 2005-11-27
    Description: Perception thresholds of rotation about three major body axes
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 299-306
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  • 23
    Publication Date: 2005-11-27
    Description: Multisensory stimulation effects on single units in vestibular nucleus of cat
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 201-208
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  • 24
    Publication Date: 2005-11-27
    Description: Preventing motion sickness in slow rotation room by incremental increases in strength of stimulus
    Keywords: BIOSCIENCES
    Type: SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 109-116
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  • 25
    Publication Date: 2005-11-27
    Description: Vestibular activity in descending medial longitudinal fasciculus
    Keywords: BIOSCIENCES
    Type: SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 237-242
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  • 26
    Publication Date: 2005-11-27
    Description: Functional organization of vestibulospinal projection in ear, emphasizing sites of termination
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 167-182
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  • 27
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    In:  CASI
    Publication Date: 2005-11-27
    Description: Scopolamine and d-amphetamine in prevention of motion sickness
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 99-108
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  • 28
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    In:  CASI
    Publication Date: 2005-11-27
    Description: Motion sickness susceptibility related to wave character and effects of sickness on performance
    Keywords: BIOSCIENCES
    Type: NAVAL AEROSPACE MED. INST. 4TH SYMP. ON THE ROLE OF THE VESTIBULAR ORGANS IN SPACE EXPLORATION 1970; P 29-32
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  • 29
    Publication Date: 2009-11-17
    Description: Psychological factors of prolonged space flight on astronaut performance
    Keywords: BIOSCIENCES
    Type: TRANS. OF THE FIRST LECTURES DEDICATED TO THE DEVELOP. OF THE SCI. HERITAGE OF K. E. TSIOLKOVSKIY APR. 1970; P 98-105
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  • 30
    Publication Date: 2006-01-11
    Description: Modelling will become increasingly important as more knowledge is accumulated, because it offers advantages in predicting reactions of individuals in a variety of situations, including novel aerospace environments, and in specifying a few parameters which should have considerable clinical significance. However, the need for continuing experimental crosschecks of these models has been illustrated by several sets of results which would not have been predicted by any existing models.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 211-219
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  • 31
    Publication Date: 2006-01-11
    Description: Evidence is presented to indicate that evoked potentials in the recurrent laryngeal, the cervical sympathetic, and the phrenic nerve, commonly reported as being elicited by vestibular nerve stimulation, may be due to stimulation of structures other than the vestibular nerve. Experiments carried out in decerebrated cats indicated that stimulation of the petrous bone and not that of the vestibular nerve is responsible for the genesis of evoked potentials in the recurrent laryngeal and the cervical sympathetic nerves. The phrenic response to electrical stimulation applied through bipolar straight electrodes appears to be the result of stimulation of the facial nerve in the facial canal by current spread along the petrous bone, since stimulation of the suspended facial nerve evoked potentials only in the phrenic nerve and not in the recurrent laryngeal nerve. These findings indicate that autonomic components of motion sickness represent the secondary reactions and not the primary responses to vestibular stimulation.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 115-123
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  • 32
    Publication Date: 2006-01-11
    Description: Motion sickness susceptibility of four normal subjects was measured in terms of duration of exposure necessary to evoke moderate malaise (MIIA) as a function of velocity in a chair rotated about a central axis tilted 10 deg with respect to gravitational upright. The subjects had little or no susceptibility to this type of rotation at 2.5 and 5.0 rpm, but with further increases in rate, the MIIA endpoint was always reached and with ever shorter test durations. Minimal provocative periods for all subjects were found at 15 or 20 rpm. Higher rotational rates dramatically reversed the vestibular stressor effect, and the subjects as a group tended to reach a plateau of relatively low susceptibility at 40 and 45 rpm. At these higher velocities, furthermore, the subjects essentially lost their sensation of being tilted off vertical. In the second half of the study, the effect of tilt angle was varied while the rotation rate was maintained at a constant 17.5 rpm. Two subjects were completely resistant to symptoms of motion sickness when rotated at 2.5 deg off vertical; with greater off-vertical angles, the susceptibility of all subjects increased sharply at first, then tapered off in a manner reflecting a Fechnerian function.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 99-103
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  • 33
    Publication Date: 2006-01-11
    Description: States of microbial imbalance as a result of human altitude chamber confinement occurred, for the most part, only in those genera and species of bacteria, yeast, and fungi which are classified as transients and are not part of the true indigenous flora of the crewmembers. Inasmuch as no crew illness events occurred and only subtle changes in the indigenous flora were noted, it appears that confinement of 56-days in a Skylab simulated environment does not mediate toward shifts in bacterial populations which have obvious clinical significance.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 12 p
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  • 34
    Publication Date: 2006-01-11
    Description: Results of a previous metric analysis and an electronic simulation of acceleratory nystagmus are given. On this basis, a tentative mathematical model for describing acceleratory nystagmus is reported. The essential content of the model is Lorente de No's neuron circuit, to which the two-factor theory of excitation has been applied.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 263-272
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  • 35
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    In:  CASI
    Publication Date: 2006-01-11
    Description: The vestibulo-ocular system is examined from the standpoint of system theory. The evolution of a mathematical model of the vestibulo-ocular system in an attempt to match more and more experimental data is followed step by step. The final model explains many characteristics of the eye movement in vestibularly induced nystagmus. The analysis of the dynamic behavior of the model at the different stages of its development is illustrated in time domain, mainly in a qualitative way.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 237-249
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  • 36
    Publication Date: 2006-01-11
    Description: Phase lag, maximal slow phase velocity, and beat frequency were measured in periodic Coriolis star nystagmus. The results have been described by Steinhausen's model of the semicircular canal system. Estimates of the biophysical constants have been obtained. It is concluded that this model is a good functional approximation for describing, and also for interpreting, the behavior of the system.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 251-262
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  • 37
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    In:  CASI
    Publication Date: 2006-01-11
    Description: Experimental evidence is presented regarding visual vestibular interaction, and the results of three studies on the subject are briefly noted. An attempt to put together some of these observations with elementary notions of a visual vestibular interaction program is shown in the form of a flow chart representation of a possible model. This is a nonlinear model in which visual and vestibular influences are linearly weighted when they are in relative agreement but switch to the more believable one when they are in disagreement. A solution to the human space orientation problem is depicted by a schema for optimal subjective orientation based on several sensory modalities.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 205-210
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  • 38
    Publication Date: 2006-01-11
    Description: Human subjects were exposed to a linear acceleration vector that rotated in the transverse plane of the skull without angular counterrotation. Lateral eye movements showed a sinusoidal change in slow phase velocity and an asymmetry or bias in the same direction as vector rotation. A model is developed that attributes the oculomotor response to otolithic mechanisms. It is suggested that the bias component is the manifestation of torsion of the statoconial plaque relative to the base of the utricular macula and that the sinusoidal component represents the translational oscillation of the statoconia. The model subsumes a hypothetical neural mechanism which allows x- and y-axis accelerations to be resolved. Derivation of equations of motion for the statoconial plaque in torsion and translation, which take into account forces acting in shear and normal to the macula, yield estimates of bias and sinusoidal components that are in qualitative agreement with the diverse experimental findings.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 221-236
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  • 39
    Publication Date: 2006-01-11
    Description: Selective stimulation of utricular gravireceptors leads to gross activation of the bulbar reticular formation where a strong interaction with evoked spino-bulbo-spinal reflex activity occurs. The utricular neurons encountered by microelectrodes in the lateral vestibular nuclei show four types of elicited activity; two of these display an increased firing rate, and two exhibit pronounced inhibitory effects. Application of a stimulus of long duration and constant intensity to the utricle has shown that rapid adaptation of the peripheral receptors is a prominent feature. The effects of selective utricular stimulation upon eye movements, as recorded by the corneoretinal potential method, have been studied in experiments on cats and monkeys and it can be firmly stated that prolonged stimulation of the utricle can evoke strong primary nystagmus, followed by a secondary nystagmus at the cessation of stimulation. The action of utricular stimulation on ocular reflexes has been examined further, with particular attention to evoked pupillary reactions in both cats and monkeys: constriction during the fast phase of the brisk conjugate eye movement, and dilatation during the flow phase.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 195-201
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  • 40
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    In:  CASI
    Publication Date: 2006-01-11
    Description: An historical survey of vestibular habituation experiments has been undertaken. Methodological problems are presented briefly, and the influence of arousal on vestibular responses is detailed. Data obtained from animals and from man are treated separately. At least for man, the term habituation may be better defined by a dynamic change in the form of vestibular responses than by a simple response reduction.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 157-193
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  • 41
    Publication Date: 2006-01-11
    Description: The vestibular end organs, after chemical fixation, were freeze dried, coated with gold and palladium, and studied in the scanning microscope. Scanning microscopy gives a good three dimensional view of the sensory areas and allows study of both gross anatomy and microstructures. Cross anatomical features of the structure of the ampullae are demonstrated. The form of the statoconia in different species of animals is shown. New aspects of the structure of the sensory hairs are revealed. The hair bundles in the central areas of the cristae and in the striola of the maculae differ structurally from the hair bundles at the periphery of the sensory regions. Furthermore, some hair bundles consisting of very short stereocilia were observed. The relationship between the cupula and the statoconial membrane to the epithelial surface is discussed.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 145-156
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  • 42
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    In:  CASI
    Publication Date: 2006-01-11
    Description: Neither alterations in environmental temperature nor moderate intake of alcohol was found to alter susceptibility to motion sickness in subjects exposed to rotation in the Pensacola slow rotation room. Scopolamine with d-amphetamine was found to be the most effective preparation for the prevention of motion sickness under the experimental conditions of the studies reported here. Promethazine in combination with d-amphetamine was in the same range of effectiveness. Drug actions suggest that acetylcholine and norepinephrine may be involved in motion sickness.
    Keywords: BIOSCIENCES
    Type: NASA, Washinton Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 109-114
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  • 43
    Publication Date: 2006-04-26
    Description: The fluid actinometry portion of the Microbial Response to Space Environment Experiment (M191) was designed for measurement of the solar energy that penetrates certain optical filter systems during exposure in space. Potassium ferrioxalate was used to measure energy at peak wavelengths of 254, 280, and 300 nanometers because of its high degree of sensitivity and its linear response to the middle ultraviolet regions.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Proc. of the Microbial Response to Space Environ. Symp.; p 169-178
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  • 44
    Publication Date: 2006-04-26
    Description: Two strains of Bacillus subtilis were exposed to components of the ultraviolet spectrum in space. Both strains possess multiple genetic markers, and one of the strains is defective in the ability to repair ultraviolet damage. The T-7 bacteriophage of Escherichia coli was also exposed to selected wavelengths and energy levels of ultraviolet light in space. Preliminary findings do not reveal anomalies in survival rates. Data are not yet available on detailed genetic analyses.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Proc. of the Microbial Response to Space Environ. Symp.; p 65-85
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  • 45
    Publication Date: 2006-04-26
    Description: Nine different species of organisms were exposed to space flight conditions during the Apollo 16 mission. Each test system was selected because it provided a quantitative method of evaluating some medically important phenomenon. The experiment design and each of the test systems are discussed.
    Keywords: BIOSCIENCES
    Type: Proc. of the Microbial Response to Space Environ. Symp.; p 3-19
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  • 46
    Publication Date: 2006-04-26
    Description: Nematospiroides dubius was tested to determine the infective potential of the third stage larvae and the egg-production and egg-viability rates of the resulting adults after they are exposed to space flight and solar ultraviolet irradiation. The results are indicative that space-flown larvae exposed to solar ultraviolet irradiation were rendered noninfective in C57 mice, whereas flight control larvae that received no solar ultraviolet irradiation matured at the same rate as the ground control larvae. However, depressed egg viability was evident in the flight control larvae.
    Keywords: BIOSCIENCES
    Type: Proc. of the Microbial Response to Space Environ. Symp.; p 51-64
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  • 47
    Publication Date: 2006-04-26
    Description: The high energy multicharged cosmic-ray-particle exposure of the Microbial Ecology Evaluation Device package on board the Apollo 16 spacecraft was monitored using cellulose nitrate, Lexan polycarbonate, nuclear emulsion, and silver chloride crystal nuclear-track detectors. The results of the analysis of these detectors include the measured particle fluences, the linear energy transfer spectra, and the integral atomic number spectrum of stopping particle density. The linear energy transfer spectrum is used to compute the fractional cell loss in human kidney (T1) cells caused by heavy particles. Because the Microbial Ecology Evaluation Device was better shielded, the high-energy multicharged particle exposure was less than that measured on the crew passive dosimeters.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Proc. of the Microbial Response to Space Environ. Symp.; p 179-189
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  • 48
    Publication Date: 2006-04-26
    Description: Lithium fluoride thermoluminescent chips were used to provide an integrated dose from the broad spectrum of ionizing radiation to the Microbial Response to Space Environment Experiment (M191). The chips were positioned in the flight hardware to provide data on ionizing radiation within specific volume segments. A uniform radiation dose of 4.8 x 0.001 plus or minus 2 x 0.0001 joule/kg resulted.
    Keywords: BIOSCIENCES
    Type: Proc. of the Microbial Response to Space Environ. Symp.; p 191-197
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  • 49
    Publication Date: 2006-04-26
    Description: The bacterium Aeromonas proteolytica was selected for studying the effects of solar irradiation on extracellular enzymes because it produces an endopeptidase that is capable of degrading proteins and a hemolysin that is active in lysing human erythrocytes. Possible alterations in the rate of enzyme production in response to the test conditions are currently underway and are not available for this preliminary report. Completed viability studies are indicative that little difference exists among the survival curves derived for cells exposed to various components of ultraviolet irradiation in space.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Proc. of the Microbial Response to Space Environ. Symp.; p 137-151
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  • 50
    Publication Date: 2006-04-26
    Description: Cultures of B. thuringiensis returned from space flight appeared to be normal to slightly affected adversely in their ability to produce three toxins that affect insects. In addition, it can be stated that B. thuringiensis spores are very resistant to ultraviolet irradiation at the individual wavelengths and energy levels previously described. Full sunlight, however, does have a detrimental effect on the viability of B. thuringiensis spores.
    Keywords: BIOSCIENCES
    Type: Proc. of the Microbial Response to Space Environ. Symp.; p 105-120
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  • 51
    Publication Date: 2006-04-26
    Description: Survival, death, and phenotype count have yielded variation in the number of fungi recovered from the controls and the flight exposed cuvettes during preliminary analysis of postflight first phase data. Also the preliminary analysis was indicative that fungi exposed to specific space flight conditions demonstrated variable survival rates and phenotype counts. Specific space flight conditions included full light space exposure for Chaetomium globosum, exposure at 300- and 254-nanometer wavelengths for Rhodotorula rubra, full light and 280-nanometer wavelength exposure for Trichophyton terrestre, and 254-nanometer wavelength exposure for Saccharomyces cerevisiae. In general, phenotype counts for flight cuvettes and survival rates for control cuvettes were higher compared with the remaining cuvettes.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Proc. of the Microbial Response to Space Environ. Symp.; p 121-135
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  • 52
    Publication Date: 2006-04-26
    Description: Bacillus subtilis spores are highly resistant to harsh environments. Therefore, in the Apollo 16 Microbial Response to Space Environment Experiment (M191), these spores were exposed to space vacuum or solar ultraviolet irradiation, or both, to estimate the change of survival for terrestrial organisms in space. The survival of the spores was determined in terms of colony-forming ability. Comparison of the flight results with results of simulation experiments on earth applying high vacuum or ultraviolet irradiation, or both, revealed no remarkable difference. Simultaneous exposure to both these space factors resulted in a synergistic effect (that is, an ultraviolet supersensitivity). Therefore, the change of survival in space is assumed to depend on the degree of protection against solar ultraviolet irradiation.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Proc. of the Microbial Response to Space Environ. Symp.; p 87-103
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  • 53
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    Publication Date: 2006-04-25
    Description: Component connection schemes of brain for trainable feedback flight control system
    Keywords: BIOSCIENCES
    Type: NIFICANT ACCOMPLISHMENTS IN SCI. AND TECHNOL. AT GODDARD SPACE FLIGHT CENTER 1970; P 292-294
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  • 54
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    Publication Date: 2006-04-02
    Description: Spacecraft equipment is usually protected from fungi and bacteria by incorporating a fungicide-bactericide in the material, by a fungicide-bactericide spray, or by reducing the relative humidity to a degree where growth will not take place. A unique method to protect delicate, expensive bearings in equipment was to maintain a pressure (with dry air or nitrogen) slightly above the outside atmosphere (few millibars) within the working parts of the equipment, thus preventing fungi from entering equipment.
    Keywords: BIOSCIENCES
    Type: Terrest. Environ. (Climatic) Criteria Guidelines for Use in Aerospace Vehicle Develop., 1973 Rev.; 2 p
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  • 55
    Publication Date: 2006-01-11
    Description: The possibility of diminished blood flow in the brain is studied as one of the factors resulting from an increase in skeletal muscle blood volume concomitant with other characteristics of motion sickness. Thermistors are implanted in the thalamus of dogs and blood flow changes are recorded while they are subjected to sinusoidal movement on a two pole swing. Results of these initial steps in a proposed long term exploration of different areas of the brain are presented.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 105-107
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  • 56
    Publication Date: 2006-01-11
    Description: Only general conclusions can be reached of the effect of Skylab simulation chamber noise on the crewmen. Two crewmen experienced a small hearing decrement in-chamber, but there was no pattern as to the ear and frequency affected. Temporary hearing threshold shifts were observed in all three crewmen postchamber. These postchamber threshold shifts were perhaps the most significant finding of the study. However, no lasting detrimental effects on the crew's hearing were found.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 8 p
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  • 57
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    Publication Date: 2006-01-11
    Description: The Skylab sleep-monitoring experiment simulated the timelines and environment expected during a 56-day Skylab mission. Two crewmembers utilized the data acquisition and analysis hardware, and their sleep characteristics were studied in an online fashion during a number of all night recording sessions. Comparison of the results of online automatic analysis with those of postmission visual data analysis was favorable, confirming the feasibility of obtaining reliable objective information concerning sleep characteristics during the Skylab missions. One crewmember exhibited definite changes in certain sleep characteristics (e.g., increased sleep latency, increased time Awake during first third of night, and decreased total sleep time) during the mission.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Skylab Med. Expt. Altitude Test (SMEAT); 21 p
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  • 58
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    Publication Date: 2006-01-11
    Description: The Skylab metabolic activity experiment determines if man's metabolic effectiveness in doing mechanical work is progressively altered by a simulated Skylab environment, including environmental factors such as slightly increased pCO2. This test identified several hardware/procedural anomalies. The most important of these were: (1) the metabolic analyzer measured carbon dioxide production and expired water too high; (2) the ergometer load module failed under continuous high workload conditions; (3) a higher than desirable number of erroneous blood pressure measurements were recorded; (4) vital capacity measurements were unreliable; and (5) anticipated crew personal exercise needs to be more structured.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 15 p
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  • 59
    Publication Date: 2006-01-11
    Description: Concern for the long term metabolic consequences of weightless flight was the basis for the conception of the Skylab medical experiment to measure mineral balance. Proper interpretation of obtained data that diminished atmospheric pressure has no appreciable effect, or at least no protective effect, on calcium metabolism. The absence of changes in calcium metabolism indicates that a stable baseline observation has been made for Skylab as far as the effects of atmosphere or calcium metabolism are concerned.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 12 p
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  • 60
    Publication Date: 2006-01-11
    Description: Evaluation of orthostatic intolerance has been achieved by the use of lower body negative pressure (LBNP). The LBNP technique, though independent of gravity, simulates its effect by exposing the legs and the lower abdomen to reduced ambient pressures. This LBNP experiment, conducted during the 56-day simulation of the Skylab environment, was designed to supply baseline information on cardiovascular responses to periodic orthostatic stress. Impaired orthostatic tolerance, manifested by the increased heart rate, diminished systolic and pulse pressure, and increased tendency to syncope in the upright position, or during LBNP, was not observed in this experiment.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 6 p
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  • 61
    Publication Date: 2006-01-11
    Description: Vestibular side effects are discussed with the aid of a conceptual framework based on an analysis of vestibular input-output relations. These side effects tend to fall into two main categories: (1) Reflex phenomena, and (2) motion sickness, a delayed epiphenomenon. Although the symptomatology of motion sickness is similar wherever experienced, both the eliciting stimuli and the opportunity to adapt may differ in different motion environments. These differences not only are exemplified when motion sickness is compared in a weightless and in a rotating environment, but they also point to important differences in the problem of preventing (or treating) motion sickness in these two very different environments.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 35-39
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  • 62
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    Publication Date: 2006-01-11
    Description: Statistically significant differences were found between Skylab simulation crews and controls for glycolytic enzymes. The absence of simultaneous controls for the pre- and postchamber analyses leaves the significance of the findings in the crew during these periods indeterminate.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Skylab Med. Expt. Altitude Test (SMEAT); 2 p
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  • 63
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    Publication Date: 2006-01-11
    Description: All routine hematological measurements for the Skylab simulation test were within normal astronaut population limits for the CDR, SPT, and PLT, with one exception: A significant lymphopenia was observed in the PLT during the post test period, possibly the reflection of increased adrenal corticoid secretion. No ultrastructural red cell membrane abnormalities were observed in any of the subjects, nor were any red corpuscle morphological abnormalities noted. Slight elevations in the PLT's red corpuscular potassium were observed in the younger corpuscles after chamber entrance and again upon egress. This probably represents newly released young red cells from hematopoietic tissue. Flame photometric analyses confirm the fact that potassium is indeed higher in the younger cells of all subjects examined.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 12 p
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  • 64
    Publication Date: 2006-01-11
    Description: Fifty-six days of residence in a Skylab-type environment produce essentially no change in the reactivity of the human immune system, as typified by the rate of RNA or DNA synthesis in small lymphocytes. The one point of divergence between the Skylab simulation crew and previous Apollo crews, a marked depression in synthesis rates on the fourteenth day after the chamber study, may be due to some technical difficulty in the experiment. Lymphocyte morphology changes paralleled functional changes.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Skylab Med. Expt. Altitude Test (SMEAT); 6 p
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  • 65
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    Publication Date: 2006-01-11
    Description: The hematology/immunology experiments in the Skylab mission study various aspects of the red blood cell, including its metabolism and life span, and blood volume changes under zero gravity conditions to determine the precise mechanism of the transient changes which have been seen on the relatively brief missions of the past.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 5 p
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  • 66
    Publication Date: 2006-01-11
    Description: A new model for the response of the semicircular canals to angular motion is postulated. This model is based on evidence that the bony canal is not compartmentalized and assumes that the ampulla wall is highly flexible. It is shown that the perilymph induces a cupula displacement far greater than that produced by the endolymph alone. The predicted dynamic behavior of the canals on the basis of this model is found to be consistent with experimental observations.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 135-141
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  • 67
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    Publication Date: 2006-01-11
    Description: Five owls were given vestibular examinations, and two of them were sacrificed to provide serial histological sections of the temporal bones. The owls exhibited a curious variability in the postrotatory head nystagmus following abrupt deceleration; sometimes a brisk nystagnus with direction opposite to that appropriate to the stimulus would occur promptly after deceleration. It was found also that owls can exhibit a remarkable head stability during angular movement of the body about any axis passing through the skull. The vestibular apparatus in the owl is larger than in man, and a prominent crista neglecta is present. The tectorial membrane, the cupula, and the otolithic membranes of the utricle, saccule, and lagena are all attached to surfaces in addition to the surfaces hearing hair cells. These attachments are very substantial in the utricular otolithic membrane and in the cupula.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Fifth Symp. on the Role of the Vestibular Organs in Space Exploration; p 127-132
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  • 68
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    Publication Date: 2006-01-11
    Description: To assure the safety and well being of the Skylab environment simulation crewmembers it was necessary to develop a medical safety plan with emergency procedures. All medical and nonmedical test and operations personnel, except those specifically exempted, were required to meet the medical standards and proficiency levels as established. Implemented programs included health care of the test crew and their families, occupational medical services for chamber operating personnel, clinical laboratory support and hypobaric and other emergency support.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 15 p
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  • 69
    Publication Date: 2006-01-11
    Description: The oral health status of three astronauts was monitored before, during and after a 56-day simulation of the Skylab mission. Laboratory and clinical parameters which are considered to be ultimately related to dental impairments were evaluated. The most notable changes were observed in increased counts of mycoplasma and S. mutans, decreased counts of enteric bacilli, decreased saliva flow rates, increased secretory IgA and salivary lysozyme levels, and increased clinical scores of dental plaque, calculus and inflammation.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Skylab Med. Expt. Altitude Test (SMEAT); 6 p
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  • 70
    Publication Date: 2006-01-11
    Description: Body fluids were assayed in this experiment to demonstrate changes which might have occurred during the 56-day chamber study in fluid and electrolyte balance, in regulation of calcium metabolism, in overall physiological and emotional adaptation to the environment, and in regulation of metabolic processes.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 14 p
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  • 71
    Publication Date: 2006-01-11
    Description: Measurement tests revealed few deviations from baseline bone mineral measurements after 56 days in a Skylab-type environment. No mineral change was observed in the right radius. One individual, however, showed a possible mineral loss in the left os calcis and another gained mineral in the right ulna. The cause of the gain is unclear but may be attributable to the heavy exercise routines engaged in by the crewmember in question. Equipment problems were identified during the experiment and rectified.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 6 p
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  • 72
    Publication Date: 2006-01-11
    Description: Prechamber, in-chamber, and postchamber blood samples taken from Skylab simulation crewmembers did not indicate significant shortening of the red cell life span during the mission. This does not suggest that the space simulation environment could not be associated with red cell enzyme changes. It does show that any changes in enzymes were not sufficiently great to significantly shorten red cell survival. There was no evidence of bone marrow erythropoetic suppression nor was there any evidence of increased red cell destruction.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Skylab Med. Expt. Altitude Test (SMEAT); 4 p
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  • 73
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    Publication Date: 2006-01-11
    Description: The cytogenetic study of the crew appears to indicate that Skylab-type environmental conditions have no deleterious effect upon chromosomal material. The findings are, however, less clear-cut than might be desired, due in large measure to confounding of the experimental design by the administration of isotope injections for the purposes of other experiments and to the lack of control subjects.
    Keywords: BIOSCIENCES
    Type: NASA. Johnson Space Center Skylab Med. Altitude Test (SMEAT); 3 p
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  • 74
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    Publication Date: 2006-01-11
    Description: The Skylab medical experiments altitude test plan is outlined. Described are the scope and objectives of the program, the management system under which it would be conducted, requirements for configuration of the test facility, test control documentation, data processing, and detailed test objectives.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 5 p
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  • 75
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    Publication Date: 2006-01-11
    Description: The objective of the Skylab medical experiment altitude test was to provide a nearly full scale simulation of a 56-day Skylab mission for studying physiological changes produced in man by the long term exposure to space conditions. Evaluated in the altitude chamber tests were human cardiovascular/hemodynamic responses, musculoskeletal/metabolic effects, endocrine/electrode factors, and neurophysiological indices.
    Keywords: BIOSCIENCES
    Type: Skylab Med. Expt. Altitude Test (SMEAT); 6 p
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  • 76
    Publication Date: 2006-03-28
    Description: A mathematical model of the human body was constructed, under the action of harmonic vibrations, in the 2.5-7 Hz frequency range. In this frequency range, the model of the human body as a vibrating system, with concentrated parameters is considered. Vertical movements of the seat and vertical components of vibrations of the human body are investigated.
    Keywords: BIOSCIENCES
    Type: Cybernetic Diagnostics of Mech. Systems with Vibro-acoustic Phenomena (NASA-TT-F-14899); p 38-40
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  • 77
    Publication Date: 2011-08-16
    Description: Low and high linear energy transfer /LET/ cyclotron-accelerated alpha particles effects on Drosophila melanogaster longevity
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    Type: ; RO(
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  • 78
    Publication Date: 2011-08-16
    Description: Botanical quarantine studies on Apollo 11 and 12 lunar soil samples effects on terrestrial plants, indicating absence of disease generating agents
    Keywords: BIOSCIENCES
    Type: ; TROPHYSICAL JOURNAL
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  • 79
    Publication Date: 2011-08-16
    Description: C 14 incorporation from labeled glucose into cerebral glycogen of normal and X ray irradiated rats
    Keywords: BIOSCIENCES
    Type: ; UGREVUE(
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  • 80
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    Publication Date: 2011-08-16
    Description: Squid head cartilage properties in terms of light and electron microscopic appearance, amino acid composition and X ray diffraction
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 81
    Publication Date: 2011-08-16
    Description: Balloon-borne monkeys possible brain damage due to cosmic rays, discussing thindown tracks and acute vasculitis
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 82
    Publication Date: 2011-08-16
    Description: Microorganisms metabolic activity effects on rocks and minerals, observing solubilization and altered IR absorption in Si-oxygen vibration region during penicillium simplicissimum growth
    Keywords: BIOSCIENCES
    Type: ; TROPHYSICAL JOURNAL
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  • 83
    Publication Date: 2011-08-16
    Description: Circadian rhythm of leaves of Phaseolus angularis plants in controlled carbon dioxide and humidity environment
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 84
    Publication Date: 2011-08-16
    Description: Halophilic bacteria growth in freeze-thaw environment, investigating cooling and warming rates and solute concentrations
    Keywords: BIOSCIENCES
    Type: ; YAL SOCIETY (
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  • 85
    Publication Date: 2011-08-16
    Description: Signal detection payoff in symmetrical auditory task, studying effect on rates and error analysis
    Keywords: BIOSCIENCES
    Type: ; VUE SCIENTIFIQUE ET
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  • 86
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    Publication Date: 2011-08-16
    Description: Bibliographical guide for literature concerning chemical evolution and origin of life
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 87
    Publication Date: 2011-08-16
    Description: Senescent Drosophila melanogaster flight muscle electron microscopic examination showing mitochondria in stages of degeneration
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    Type: ; ACE(
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  • 88
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    Publication Date: 2011-08-16
    Description: Unicellular hot spring acidophilic alga Cyanidium cadarium cultured in pure carbon dioxide, examining packed cell volume, oxygen production and growth rate
    Keywords: BIOSCIENCES
    Type: ; STITUTION OF RADIO A
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  • 89
    Publication Date: 2011-08-16
    Description: Mathematical model of human pituitary gland mechanism controlling secretions of serum growth hormone in response to glucose deficiency
    Keywords: BIOSCIENCES
    Type: ; 47 (
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  • 90
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    Publication Date: 2011-08-16
    Description: Extraterrestrial life hypotheses, citing astronomical considerations, inorganic chemical evolution and prebiotic synthesis with emphasis on Mars exploration for microorganisms
    Keywords: BIOSCIENCES
    Type: ; VUE SCIENTIFIQUE ET
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  • 91
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    Publication Date: 2011-08-16
    Description: Psychrometric chart for physiological research involving moist air thermodynamic properties
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 92
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    Publication Date: 2011-08-16
    Description: Photosystem II and oxygen evolution kinetics
    Keywords: BIOSCIENCES
    Type: ; VUE SCIENTIFIQUE ET
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  • 93
    Publication Date: 2011-08-16
    Description: Hibernation and glycerol production in wasps Ichneumonidea, discussing possible physiological cryoprotective function
    Keywords: BIOSCIENCES
    Type: ; VIGATION (
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  • 94
    Publication Date: 2011-08-16
    Description: Reaction kinetics of microbial sterilization in ultrahigh vacuum and in outer space
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 95
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    Publication Date: 2011-08-16
    Description: Apollo 11 lunar rock samples examined for clues to moon life
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 96
    Publication Date: 2011-08-16
    Description: Human body core temperature control dependence during exercise on heat dissipation, noting sweating control
    Keywords: BIOSCIENCES
    Type: ; 47 (
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  • 97
    Publication Date: 2011-08-16
    Description: Serum growth hormone response to hypoglycemia in man following insulin administration, reviewing lumped parameter model
    Keywords: BIOSCIENCES
    Type: ; SEARCH(
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  • 98
    Publication Date: 2011-08-16
    Description: Plasma free fatty acids and glucose relative role in contribution to metabolic state and energy production in partially hepatectomized rats
    Keywords: BIOSCIENCES
    Type: ; YAL SOCIETY (
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  • 99
    Publication Date: 2011-08-16
    Description: Mitosis control assuming existence of functional relationship between potential level and mitotic activity, using classical membrane potential theory
    Keywords: BIOSCIENCES
    Type: ; IBRATIONAL COMBUSTIO
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  • 100
    Publication Date: 2011-08-16
    Description: Human cortisol intermittent secretion during early morning sleep and sleep-wake cycle, examining adrenal activity
    Keywords: BIOSCIENCES
    Type: ; VUE SCIENTIFIQUE ET
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