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  • Articles  (80)
  • Superconducting devices  (45)
  • 07.65  (33)
  • Chemical Engineering
  • Electronic structure and strongly correlated systems
  • Saccharomyces cerevisiae
  • Springer  (80)
  • 1980-1984  (80)
  • Physics  (80)
  • 1
    ISSN: 1432-0649
    Keywords: 07.65 ; 32
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The application of laser deceleration and monochromatization of atoms in the schemes of single atom fluorescent detection is examined. The analysis performed shows that the use of resonant-light pressure in experiments with atomic beams enables one to obtain an ultimate value of detection selectivity that ranges from 1013 to 1016.
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  • 2
    ISSN: 1573-6881
    Keywords: H+-ATPase complex ; assembly defect ; Saccharomyces cerevisiae ; mitochondrial biogenesis ; membrane association
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Physics
    Notes: Abstract We have investigated the extent to which the assembly of the cytoplasmically synthesized subunits of the H+-ATPase can proceed in a mtDNA-less (rho°) strain of yeast, which is not capable of mitochondrial protein synthesis. Three of the membrane sector proteins of the yeast H+-ATPase are synthesized in the mitochondria, and it is important to determine whether the presence of these subunits is essential for the assembly of the imported subunits to the inner mitochondrial membrane. A monoclonal antibody against the cytoplasmically synthesized β-subunit of the H+-ATPase was used to immunoprecipitate the assembled subunits of the enzyme complex. Our results indicate that the imported subunits of the H+-ATPase can be assembled in this mutant, into a defective complex which could be shown to be associated with the mitochondrial membrane by the analysis of the Arrhenius kinetics of the mutant mitochondrial ATPase activity.
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  • 3
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 123-141 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si riesamina la strumentalizzazione adatta all’acquisizione di segnali biomagnetici. Si studiano separatamente i componenti di base del magnetometro, cioè gli SQUID, i trasformatori di flusso e i dewar. Si discutono i possibili miglioramenti alla strumentazione attuale e alle apparecchiature complete comprendenti scudi ferromagnetici o di correnti a vortice e si valuta la loro efficenza.
    Notes: Summary The instrumentation suitable for the acquisition of biomagnetic signals is reviewed. The basic magnetometer components,i.e. SQUIDs, flux transformers and dewars, are studied separately. Possible improvements to the present instrumentation as well as complete set-ups including ferromagnetic or eddy current shields are discussed and their efficiency evaluated.
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  • 4
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 142-152 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si sviluppa un formalismo per la descrizione vettoriale e tensoriale di una procedura di bilanciamento e si sottolinea un metodo di bilanciamento di campo e di primo gradiente. Si discutono l’apparecchiatura sperimentale e le misurazioni del vettore di modo comune del primo gradienteC G 1.
    Notes: Summary A formalism for the vector and tensor description of a balancing procedure is developed and a first-gradient and field-balancing method is outlined. The experimental apparatus and measurements of the first-gradient common-mode vector,C G 1, are discussed.
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  • 5
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    Applied physics 30 (1983), S. 83-86 
    ISSN: 1432-0649
    Keywords: 07.65 ; 34 ; 32
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The sensitivity of laser spectroscopy on barium ions stored in a radio frequency quadrupole trap was drastically increased by using hydrogen for quenching the optically pumped metastable states. The attained fluorescence intensity per ion permits the detection of single ions. The method will be applied to environmental studies on actinides.
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  • 6
    ISSN: 1432-0649
    Keywords: 06 ; 07.60 ; 07.65
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We describe a new and highly effective optical frequency discriminator and laser stabilization system based on signals reflected from a stable Fabry-Perot reference interferometer. High sensitivity for detection of resonance information is achieved by optical heterodyne detection with sidebands produced by rf phase modulation. Physical, optical, and electronic aspects of this discriminator/laser frequency stabilization system are considered in detail. We show that a high-speed domain exists in which the system responds to the phase (rather than frequency) change of the laser; thus with suitable design the servo loop bandwidth is not limited by the cavity response time. We report diagnostic experiments in which a dye laser and gas laser were independently locked to one stable cavity. Because of the precautions employed, the observed sub-100 Hz beat line width shows that the lasers were this stable. Applications of this system of laser stabilization include precision laser spectroscopy and interferometric gravity-wave detectors.
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  • 7
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    Applied physics 32 (1983), S. 145-152 
    ISSN: 1432-0649
    Keywords: 07.65
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Frequency modulation (FM) spectroscopy is a new method of optical heterodyne spectroscopy capable of sensitive and rapid measurement of the absorption or dispersion associated with narrow spectral features. The absorption or dispersion is measured by detecting the heterodyne beat signal that occurs when the FM optical spectrum of the probe wave is distorted by the spectral feature of interest. A short historical perspective and survey of the FM spectroscopy work performed to date is presented. Expressions describing the nature of the beat signal are derived. Theoretical lineshapes for a variety of experimental conditions are given. A signal-to-noise analysis is carried out to determine the ultimate sensitivity limits.
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  • 8
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    Applied physics 31 (1983), S. 15-17 
    ISSN: 1432-0649
    Keywords: 35 ; 07.65 ; 42.60
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract An absorption method which permits time-selective measurements at different wavelengths has been developed in order to explore magnetic field effects on photoinduced electron transfer reactions in linked and unlinked donor-acceptor systems.
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  • 9
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    Applied physics 30 (1983), S. 99-104 
    ISSN: 1432-0649
    Keywords: 42.60 ; 07.65
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Some new experimental data on the time development of ultrashort superfluorescence (SF) in the dye solution are presented. The correlation between temporal behaviour change and the change of the spectral and spatial intensity distribution gives direct evidence of the important role of the selffocusing phenomenon in the formation of the ultrashort SF pulse synchronized with the pumping one. The oriental relaxation of solvent molecules in the dye solution not only influences the duration of the dye SF via the selffocusing mechanism but also causes a temporal change of spontaneous emission spectrum. At least two different relaxation times were found in the fluorescence spectrum of the dye in several polar solutions.
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  • 10
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    Applied physics 32 (1983), S. 93-95 
    ISSN: 1432-0649
    Keywords: 07.65 ; 42.40 ; 82.50
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A new experimental method for measuring the optical anisotropy induced at photochemical reactions is proposed. The method is based on polarization holography and is a zero-background high sensitive technique. It is used to measure the molecular dichroism of fluorescein and the birefrigence induced at the additional photopolymerization of PMMA.
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  • 11
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 175-183 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto In questo lavoro si tratta il problema dell’ottimizzazione di sistemi di sensori gradiometrici metrici superconduttori di secondo ordine che sono stati progettati per la misurazione di campi magnetici deboli disomogenei in un ambiente disturbato magneticamente. Si considerano le condizioni di massimo rapporto segnale-rumore dell’uscita del quantomagnetometro superconduttote (SQM). Si analizza l’influenza dei parametri misurati della sorgente del segnale, del rumore di una sorgente di disturbo esterna e di quello proprio del magnetometro sulla selezione della lunghezza di base del gradiometro.
    Notes: Summary In this paper we deal with an optimization problem of the second-order superconducting gradiometric sensor systems that have been designed for measurement of the weak inhomogeneous magnetic fields in a magnetically disturbed environment. The conditions of maximum signalto-noise ratio of the output of superconducting quantum magnetometers (SQM) are considered. The influence of measured signal source parameters, of an outside disturbing source and of the own noise of the magnetometer on the gradiometer base length selection is analysed.
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  • 12
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 356-367 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Sono state esaminate l’idealità e la sensibilità di parecchi conduttori magnetocardiografici vettoriali usando un modello inomogeneo fisico del tronco. Si è trovato che la componente antero-posterioreX vettore magnetico del cuore è la piú facile da scoprire. Si suggeriscono conduttori ideali per le altre due componenti. Comunque questi hanno una sensibilità inferiore. Le differenze rispetto ai risultati di precedenti ricercatori sono state spiegate con le differenze tra i modelli.
    Notes: Summary The ideality and sensitivity of several vector magnetocardiographic leads were tested by using an inhomogeneous, physical torso model. The postero-anterior component of the heart’s magnetic vector was found easiest to detect. New, more ideal leads for the other two components are suggested. However, these have lower sensitivity. The differences from the results of former investigators can be explained by the differences of the models.
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  • 13
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 203-213 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è studiato lo spettro del rumore di un gradiometro superconduttore a derivata secon da in un agglomerato urbano. I dati sono stati ottenuti dal gradiometro con tre accelerometri ortogonali e un magnetometro a flussometro elettronico triassiale attaccato al dewar. Questi dati sono stati analizzati usando tecniche di elaborazione dei segnali, soprattutto un cancellatore adattativo di rumori, per ridurre i rumori nei dati del gradiometro. I risultati mostrano qui che il rumore dell’esterno e/o il rumore del movimento del dewar possono essere ridotti di 40 dB in potenza di rumore. Si è anche mostrato che, nel caso di basso rapporto segnale-rumore (S/N∼1), può essere estratta un’onda sunusoidale di 10 Hz. Questa tecnica non solo promette riduzione dei rumori, ma ha anche lo scopo d’identificare i segnali di rumore che potrebbero essere veramente considerati parte del responso evocato. L’analisi dei dati che contengono i responsi evocati è ora in corso.
    Notes: Summary The noise spectrum of a superconducting second-derivative gradiometer has been investigated in an urban environment. Data have been acquired from the gradiometer with three orthogonal accelerometers and a triaxial fluxgate magnetometer attached to the dewar. These data have been analyzed by using signal processing techniques, primarily an adaptive noise canceller, to reduce noise in the gradiometer data. Results shown here indicate that the environmental noise and/or the dewar motion noise can be reduced as much as 40 dB in noise power. It is also shown, in the case of poor signal-to-noise ratio (S/N∼1), that a 10 Hz sine wave can be extracted. This technique not only shows promise for noise reduction, but also aids in the identification of noise signals which might be misconstrued as part of the evoked response. Analysis of data containing evoked response is now underway.
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  • 14
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 153-165 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si stabiliscono princípi per il progetto di sistemi di spire che generano campi magnetici distanti che diminuiscono secondo una potenza inversa alta della distanza. Secondo un principio di reciprocità queste disposizioni, quando usate come sensori in magnetometri ad induzione e SQUID, hanno una sensibilità intrinsecamento bassa per sorgenti distanti del campo magnetico.
    Notes: Summary Principles are established for the design of coil arrays which generate distant magnetic fields diminishing as a high inverse power of the distance. By a principle of reciprocity these arrays, when used as sensors in induction and SQUID magnetometers, have an inherently low sensitivity to distant sources of magnetic field.
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  • 15
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 166-174 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è costruito un magnetometro SQUID differenziale a 3 canali per la misurazione simultanea delle 3 componenti ortogonali del campo magnetico nella stessa posizione. Si descrive la struttura dell’apparecchio e si mostrano i dati MCG misurati. Si discutono gli effetti d’interferenza tra i canali.
    Notes: Summary We have constructed a three-channel differential SQUID magnetometer for the simultaneous measurement of the three orthogonal components of the magnetic field in the same location. The structure of the device is described and MCG data measured are shown. Interference effects between the channels are discussed.
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  • 16
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 184-194 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è costruito espressamente un sistema SQUID in un ospedale di Parigi, che permette indagini neuromagnetiche attinenti con applicazioni cliniche. Un gradiometro simmetrico di second’ordine lavora entro uno schermo per corrente parassite. Ciò è designato ad ottimizzare il costo e l’efficienza del sistema. Le sue prestazioni sono state sperimentate con dati da pazienti e da soggetti normali.
    Notes: Summary A SQUID system was specially built in a Parisian hospital, allowing neuromagnetic investigations dealing with clinical applications. A second-order symmetrical gradiometer works inside an eddy current shield. This was designed for optimizing the cost and the efficiency of the system. Its performances were tested with data from patients and normal subjects.
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  • 17
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 224-230 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si descrive la strumentazione per le applicazioni biomagnetiche. Le piccole dimensioni e la leggerezza del gradiometro SQUID permettono il facile trasporto e posizionamento dello strumento, rendendo cosí possibile le misurazioni biomagnetiche in una qualsiasi locazione in cui non ci siano rumori. L’apparecchio è provvisto di un alimentatore a batteria e, se riempito con 60 cm3 di elio liquido, funzionerà initerrottamente per 6 ore. L’apparecchio è adatto per la magnetocardiografia.
    Notes: Summary The instrumentation for biomagnetic applications is described. The small size and weight of the SQUID gradiometer permit easy transport and positioning of the instrument, thus making biomagnetic measurements possible in any noise-free location. The equipment is provided with a battery power supply, and, when filled with 60 cm3 of liquid helium, will operate continuously for 6 h. The device is suitable for magnetocardiography.
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  • 18
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 301-310 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si confrontano i magnetocardiogrammi misurati in un caso di infarto miocardico anterolaterale con i corrispondenti magnetocardiogrammi simulati. I cambiamenti piú notevoli nell’MCG misurato si sono osservati nelle parti superiori e inferiori del torace come previsto dalla simulazione.
    Notes: Summary The MCGs measured in a case of an anterolateral myocardial infarction were compared with the corresponding simulated MCGs. The most distinctive changes in the measured MCGs were observed in the upper and lower parts of the thorax as predicted by the simulation.
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  • 19
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 558-566 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto La conduttività elettrica delle lesioni cerebrali varia con situazioni patologiche come l’edema e la calcificazione. È stato studiato mediante una simulazione con il computer l’effetto delle disomogeneità dei tessuti delle lesioni cerebrali sulle distribuzioni spaziali dei potenziali elettrici e dei campi magnetici sulla superficie del capo.
    Notes: Summary The electrical conductivity of brain lesions varies with pathological situations such as edema and calcification. The effect of the tissue inhomogeneities of brain lesions on spatial distributions of electrical potentials and magnetic fields over the surface of the head was studied by means of a computer simulation.
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  • 20
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è sviluppato un metodo magnetico per misurazioni dirette non invasive del ferro di immagazzinamento epatico umano con uno suscettometro SQUID. Le determinazioni magneticain vivo e chimicain vitro del ferro epatico non eme sono strettamente correlate. Le misurazioni magnetiche dei depositi di ferro sono utili, dal punto di vista clinico, nella diagnosi dei disordini nel metabolismo del ferro.
    Notes: Summary A magnetic method for direct noninvasive measurements of human hepatic storage iron with a SQUID susceptometer has been developed.In vivo magnetic andin vitro chemical determinations of liver nonheme iron are closely correlated. Magnetic measurements of iron stores are clinically useful in the diagnosis of disorders of iron metabolism.
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  • 21
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 594-607 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Il problema inverso nella misurazione magnetical del polmone è stato studiato con un metodo che usa le ipotetiche distribuzioni del pulviscolo magnetico. Si sono fatte le minimizzazioni non vincolate e vincolate di una funzione obiettiva. Le simulazioni e l’analisi hanno mostrato l’efficacia del metodo.
    Notes: Summary The inverse problem in the magnetic measurement of the lung was studied with a method using hypothetical distributions of magnetic dust. Both unconstrained and constrained minimizations of an objective function were performed. Simulations and analysis showed the efficacy of the method.
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  • 22
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 608-616 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Si è trovato che la velocità di decadimento del campo residuo ottenuto tramite magnetizzazione delle particelle ferromagnetiche trattenute nei polmoni dei saldatori è associato a fattori come la quantità di polvere trattenuta, il curriculum lavorativo e la consuetudine di fumare. Una velocità di decadimento piú rapida appare correlata con un piú rapido smaltimento delle particelle di fumo di saldatura nei fumatori.
    Notes: Summary It was found that the rate of decay of the remanent field obtained through magnetization of ferrimagnetic particles retained in the lungs of are welders is associated with factors such as amount of dust retained, occupational history and smoking habits. A faster decay rate was found to correlate with a faster clearance of welding fume particles in smokers
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  • 23
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 617-623 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Particelle ferromagnetiche immesse per via intratracheale nei polmoni sono fagocitate da macrofagi alveolari. Dopo che queste particelle sono state magnetizzate dal campo esterno, esse producono un campo residuo che decade rapidamente a causa del disallineamento delle particelle dovuto al movimento citoplasmatico (rilassamento). I cambiamenti nel valore di rilassamento nel tempo successivo all’immissione potrebbero essere connessi alla mobilità citoplasmatica.
    Notes: Summary Ferrimagnetic particles instilled intratracheally into the lungs are phagocytized by alveolar macrophages. After these particles are magnetized by an external field, they produce a remanent field which decays rapidly due to particle misalignment from cytoplasmic motion (relaxation). Changes in relaxation rate with time following instillation might be related to cytoplasmic motility.
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  • 24
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 624-641 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto La pletismografia a suscettività magnetica (MSPG) è un nuovo metodo proposto per controllare i cambiamenti del volume cardiaco. Si riesaminano il principio di misurazione e i lavori recenti di altri ricercatori. Si studia l’effetto del movimento legato al cuore della cassa toracica anteriore sul segnale MSPG.I risultati suggeriscono che il movimento del confine cassa toracica-aria può contribuire in modo significativo (∼75%) al segnale MSPG quando è registrato vicino al cuore.
    Notes: Summary Magnetic-susceptibility plethysmography (MSPG) is a new method proposed for monitoring cardiac-volume changes. The measurement principle and recent work by other investigators are reviewed. The effect of the cardiac-related motion of the anterior chest wall on the MSPG signal is studied. The results suggest that the motion of the chest-wall-air boundary may contribute significantly (∼75%) to the MSPG signal when recorded near the heart.
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  • 25
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 642-649 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto È stata esaminata la forma d’onda d’impulso per il magnetomiogramma (MMG) dell’arto inferiore destro umano. Le durate tipiche degl’impulsi sono di circa (10÷20) ms. La variazione spaziale del MMG suggerisce un’origine nei muscoli anteriori della tibia.
    Notes: Summary The pulse wave form for the magnetomyogram (MMG) of the human right leg was examined. The typical pulse durations are about (10÷20) ms. The spatial variation of the MMG suggests a source in the anterior muscles.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 650-659 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Le ricerche sul campo magnetico intorno alla gamba umana con l’uso di un magnetometro SQUID producono risultati consistenti e riproducibili che possono essere rappresentati mediamente due linee di corrente, orientate inversamente, parallele all’asse della gamba. I campi sono condizionati dall’attività muscolare, che decade col tempo di rilassamento della gamba.
    Notes: Summary Investigations of the magnetic field around the human leg using a SQUID magnetometer yield consistent, reproducible results which can be modelled by 2 oppositely oriented line currents parallel to the leg axis. The fields are affected by muscle activity, decaying with the time of relaxation of the leg.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 195-202 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si mostra che miglioramenti sostanziali possono essere ottenuti nelle proprietà di schermatura di una stanza schermata da corrente parassite coprendo l’accesso con lamine conduttrici. I risultati suggeriscono che non è necessario installare una porta conduttrice e mostrano che è il caso di coprire una piccola parte della porta in modo permanente.
    Notes: Summary We show that substantial improvements can be obtained in the shielding properties of an eddy-current-shielded room by covering the doorway with conductive plates. Results suggest that it is unnecessary to install a conductive door and show that it is worthwhile covering a small part of the doorway permanently.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 248-254 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Il magnetocardiogramma ad alta risoluzione è stato registrato mediante magnetometri superconduttori in 12 volontari sani utilizzando la camera schermata di Berlino per ridurre il livello di rumore elettromagnetico. La morfologia del trattoPR magnetico è caratterizzata dalle «rampe» in precedenza osservate, sulle quali s’inseriscono segnali. A volte la forma d’onda appare complessa.
    Notes: Summary ThePR interval of magnetocardiograms has been measured with a SQUID sensor in the Berlin magnetically shielded room. In addition to previously reported ramps with isolated superimposed signals in several cases a structured morphology has been found.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 266-279 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Sono stati osservati segnali degradanti nel segmentoPR dei magnetocardiogrammi normali registrati da 5 cani. Sono state osservate rampe maggiori dopo aver indotto con farmaci il blocco del nodo atrioventricolare di primo grado, ed è stata osservata una completa ripolarizzazione atriale a seguito d’isolate contrazioni atriali in due animali con blocco di secondo grado. Queste rampe, che variano fino a 6.7 pT in ampiezza e provengono dagli atri, possono complicare l’individuazione magnetica dell’attività di His-Purkinje.
    Notes: Summary Sloping signals were observed in thePR segment of normal magnetocardiograms recorded from five dogs. Larger ramps were observed after first-degree AV nodal blockade was induced pharmacologically, and complete atrial repolarization was observed following isolated atrial contractions in two animals with second-degree block. These ramps, ranging up to 6.7 pT in size and arising from the atria, may complicate magnetic detection of His-Purkinje activity.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 231-247 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; PACS. 85.25 ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto La motivazione fondamentale per lo studio dei fenomeni elettrofisiologici cardiaci tramite il metodo biomagnetico è dovuta al fatto che questa tecnica offre un’alta risoluzione spaziale e sembra fornire informazioni complementari rispetto alle sole registrazioni elettriche. Fino ad oggi l’interesse degli studiosi si è concentrato su due differenti fenomeni cardiaci: 1) lo studio dell’attività del sistema di conduzione atrioventricolare e 2) lo studio della depolarizzazione ventricolare anormalmente ritardata (late potentials). L’interesse clinico per lo studio non invasivo del sistema di His-Purkinje (HPS) è ben noto. Registrazioni cliniche non invasive di late potentials sono particolarmente desiderabili in quanto possono essere preziosi indicatori di rischio di morte improvvisa. In questo lavoro si presenta una rassegna sullo stato delle ricerche in entrambi i campi d’indagine.
    Notes: Summary The fundamental motivation for investigating cardiac electrophysiological phenomena by means of the biomagnetic method has been that this technique should have added spatial resolution and provided complementary information as opposed to electric recordings only. So far the interest of experimentalists has been concentrated on two different kinds of cardiac phenomena: 1) the study of the activity of the cardiac conduction system and 2) of abnormally delayed ventricular depolarization (late potentials). The clinical interest for the noninvasive investigation of the His-Purkinje system (HPS) is well known. Noninvasive clinical recording of late potentials is particularly desirable as they seem to be precious markers for risk of sudden death. A review of the state of research in both fields is presented in this paper.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 280-290 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Ein dal 1980 è iniziato uno studio sistematico dell’attività del sistema di His-Purkjnje (HPS) su soggetti normali e patologici con il metodo biomagnetico. Allo scopo di risolvere il problema di quanta parte dei segnali misurati sia attribuibile al sistema di His-Purkinje e quanta piuttosto alla ripolarizzazione atriale, è stata recentemente sviluppata una strumentazione appositamente disegnata per misure sul HPS e con una sensibilità di $$20fT/\sqrt {Hz}$$ nella banda di frequenze interessanti ((0.5÷300) Hz). Al contempo si è altresí sviluppato un nuovo modello teorico in stretta corrispondenza con le caratteristiche anatomiche del HPS che fornisce una distribuzione di campo magnetico sul torace in buon accordo qualitativo con i risultati sperimentali.
    Notes: Summary Since 1980, systematic investigations of the activity of the His-Purkinje system (HPS) by the biomagnetic method have been reported on both normal subjects and patients affected by different kinds of conduction disturbances. A first attempt to interpret the experimental results by means of a theoretical model satisfactorily accounted for the measured «ramp» patterns. Moreover, a good temporal coincidence was observed between magnetic signals and invasively recorded His bundle electrograms (HBE). An alternative explanation of the «ramp» pattern, in terms of atrial repolarization, has been recently proposed on the basis of animal experimental investigation. In order to try to solve this problem, we have carried out a twofold approach: a new second-order gradiometer, specifically designed for HPS activity investigation has been successfully set up and tested; it provides a sensitivity of $$20fT/\sqrt {Hz}$$ in the band width of interest ((0.5÷300) Hz). Second, a new model based on a closer correspondence to anatomical features of the HPS has been developed. This model provides well-defined patterns which are in quite good agreement with experimental results.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 311-323 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Si registra la distribuzione sia del potenziale elettrico cardiaco sulla superficie del corpo che del campo magnetico cardiaco vicino al torace e alla schiena in momenti fissi del ciclo cardiaco. Le caratteristiche generali di entrambi i tipi di mappa sono semplici e riproducibili, inoltre ciascuno di essi fornisce informazioni differenti.
    Notes: Summary The distribution of both the cardiac electric potential on the body surface and the cardiac magnetic field near the chest and back is recorded at fixed time instants of the heart cycle. The general features of both types of maps are simple and reproducible, moreover they both reveal different information.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 324-339 
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    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Sono stati eseguiti calcoli numerici sul campo magnetico generato dal cuore durante la depolarizzazione ventricolare. Lo scopo di questo lavoro è studiare il contributo d’inomogeneità nel conduttore di volume al campo totale e stabilire l’influenza dei gradiometri usati nelle registrazioni sperimentali.
    Notes: Summary Numerical computations were performed on the magnetic field generated by the heart during ventricular depolarization. The purpose of this study was to investigate the contribution of inhomogeneities in the volume conductor to the total field and to establish the influence of gradiometers as used in experimental recordings.
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    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Description / Table of Contents: Riassunto Il magnetocardiogramma ad alta risoluzione, registrato in 22 pazienti affetti da pregresso infarto del miocardio, ha permesso di rilevare in 3 casi la presenza di segnali di ampiezza tra 0.4 e 3 pT temporalmente correlati a depolarizzazioni tardive elettriche. Si discutono de differenze tra segnali magnetici ed elettrici e il loro possibile significato fisiopatologico.
    Notes: Summary High-resolution magnetocardiograms of patients with recent myocardial infarction have been recorded. In three cases, signals have been found in theST segment that are time correlated with simultaneously recorded late electric potentials.
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    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Description / Table of Contents: Riassunto Per studiare l’effetto della geometria del conduttore di volume, sono stati compiuti esperimenti usando cuori di coniglio isolati. È stato osservato un aumento del segnale magnetico con l’aumentare della dimensione del conduttore di volume. Si discutono i risultati usando un dipolo di corrente a origine fissa e un modello di sorgente di tensione per il cuore.
    Notes: Summary To study the effect of the volume conductor geometry on the MCG, experiments using isolated rabbit hearts were done. An increase of the magnetic signal when increasing the volume conductor’s size was observed. The results are discussed by using a fixed-origin current dipole and a voltage source model for the heart.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 368-378 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Si presentano le prime misurazioni del campo magnetico associato col potenziale d’azione in un fascio di fibre cardiache di Purkinje isolate. Le nostre scoperte dimonstrano la fattibilità dell’uso di tecniche magnetiche per misurare le correnti assiali in un gruppo di cellule cardiache ad attività spontanea.
    Notes: Summary We present the first measurements of the magnetic field associated with the action potential in a bundle of isolated cardiac Purkinje fibers. Our findings demonstrate the feasibility of using magnetic techniques to measure the axial current in a bundle of spontaneously active cardiac cells.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 379-409 
    ISSN: 0392-6737
    Keywords: Biomagnetic (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Si riesaminano le ricerche sul campo magnetico indotto compiute negli ultimi due anni. Questi studi hanno mostrato che la tecnica magnetica si puó usare 1) per rivelare aspetti complementari delle fonti di corrente comuni al potenziale indotto, 2) per identificare l’organizzazione della corteccia cerebrale e delle arce subcorticali e 3) per misurare le proprietà funzionali delle aree neurali attive le cui posizioni sono identificate.
    Notes: Summary Research in the evoked magnetic field reported in the last two years is reviewed. The studies have shown that the magnetic technique may be used 1) to reveal complementary aspects of the current sources common to evoked potential, 2) to identify the organization of the cerebral cortex and subcortical areas of the brain and 3) to measure functional properties of the active neural areas whose locations are identified.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 410-419 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Il campo magnetico corticale osservato, suscitato da uno stimolo presentato a varie eccentricità nel campo visivo, è stato interpretato come derivante da dipoli di corrente lungo la scissura longitudinale. La profondità della sorgente aumenta con l’aumento dell’eccentricità, in accordo con la classica mappatura retinotopica.
    Notes: Summary The observed cortical magnetic field evoked by a stimulus presented at various eccentricities in the visual field was interpreted as arising from current dipoles along the longitudinal fissure. The depth of the source increased as the eccentricity was increased, in agreement with the classical retinotopic map.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 420-428 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si esamiano i componenti elettrici e magnetici della risposta stimolata visiva del cervello, con picchi a 120 e 180 ms dopo lo stimolo. I risultati mostrano che entrambi i componenti magnetici sono localizzati nella corteccia occipitale superficiale tangenziale al cuoio capelluto. La distribuzione diM120 suggerisce che i generatori dei componenti elettrici e magnetici sono correlati, ma il campo magnetico elettrico registrato è una modificazione elaborata di quello prodotto dalla sorgente.
    Notes: Summary Corresponding electrical and magnetic components of the brain’s visual evoked response peaking at 120 and 180 ms poststimulus are examined. Results show that both magnetic components are localized in the superficial occipital cortex tangential to the scalp. The distribution ofM120 suggests that the generators for the electrical and magnetic components are related, but the electrical field recorded is an elaborate modification of that produced by the source.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 429-437 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Campi magnetici indotti dalla sensibilità somatica sono stati confrontati con i corrispondenti potenziali elettrici sul cuoio capelluto allo scopo di studiare le loro sorgenti neurali. Le mappature delle risposte magnetiche hanno mostrato attività a livello delle cortecce di sensibilità somatica primarie e secondarie. Ulteriori sorgenti oltre a queste aree sembrano essere coinvolte nella generazione dei potenziali del cuoio capelluto a vertice somatosensoriali.
    Notes: Summary Somatosensory evoked magnetic fields were compared with corresponding electric scalp potentials in order to study their neural sources. Mappings of the magnetic responses showed activity at the primary and secondary somatosensory cortices. Additional sources besides these areas seem to be involved in the generation of the somatosensory vertex scalp potentials.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 438-459 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto In questo lavoro si presentano alcuni tentativi di considerazioni modello, basati sul concetto di dipolo di corrente equivalente per tener conto delle risposte sonore stimolate osservate, con lo scopo di tentare un confronto delle variazioni in ampiezza e latenza con calcoli basati sul modello di nervo altamente semplificato di Rall. Si presenta un’analisi fenomenologica dei dati sperimentali sul campo magnetico sonoro tardo evocato dalla corteccia uditiva umana. Qui si pone l’accento sulle relazioni tra le proprietà del segnale (per esempio, ampiezza e latenza) e tra le proprietà del segnale e le proprietà dello stimolo (per esempio, ampiezza/latenza e frequenza in discesa relativa Δf/f per uno stimolo con frequenza in discesa) piuttosto che su problemi correlati con la posizione del dipolo di corrente equivalente, per esempio l’organizzazione tonotopica discussa da Elberlinget al. e Romaniet al. Si presentano alcuni risultati di un calcolo numerico basato su un modello a cavo lineare e li si confronta con i risultati sperimentali.
    Notes: Summary In this paper we present some tentative model considerations, based on the concept of an equivalent current dipole to account for observed auditory evoked responses, with the aim of attempting a comparison of variations in amplitude and latency with calculations based on Rall’s greatly simplified nerve model. A phenomenological analysis of experimental data on the late, auditory evoked magnetic field from the human auditory cortex is presented. The emphasis is here placed on relations between signal properties (e.g. amplitude and latency) and between signal properties and stimulus properties (e.g. amplitude/latency and relative frequency glide Δf/f for a frequency glide stimulus) rather than on questions related to the location of the equivalent current dipole,e.g. the tonotopic organization discussed by Elberlinget al. and by Romaniet al.. Some results of a numerical calculation based on a linear-cable model are presented and compared with experimental results.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 471-483 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Le sorgenti di risposte uditive magnetiche ed electtriche stimolate sono state formate con dipoli a corrente multipli. L’attività a livello delle cortecce uditive, 2.6 cm al di sotto della calotta cranica, spiega la distribuzione di campo osservata $$\overline {N100m}$$ . Un’ulteriore sorgente di corrente vicino al vertice è necessaria per spiegare le corrispondenti distribuzioni di potenziale. La posizione delle sorgenti di corrente di $$\overline {N100m}$$ non ha mostrato alcuna dipendenza sistematica dalla frequenza tonale.
    Notes: Summary The sources of auditory evoked electric and magnetic responses were modelled with multiple current dipoles. The activity at the auditory cortices, 2.6 cm beneath the skull, explains the observed $$\overline {N100m}$$ field distribution. An additional current source near the vertex is needed to explain the corresponding potential distributions. The locations of the current sources of $$\overline {N100m}$$ did not show any systematic dependence on the tonal frequency.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 460-470 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Sono stati registrati campi magnetici uditivi indotti (AEF) e potenziali uditivi indotti EEG (AEP) dalle regioni corticali uditive destra e sinistra di 12 soggetti normali adulti. Il sensore magnetico era un gradiometro SQUID a forma di otto con una linea di base di 4 cm orientato in modo da essere massimamente sensibile a un dipolo di corrente orientato perpendicolarmente alla fissure di Sylvio. Gli stimoli erano impulsi sonori di 1 kHz, lunghi 100 ms con un intervallo modale tra stimoli di 700 ms emessi a livelli di pressione sonora di 40, 60, 80 e 100 dB. Si è trovato che l’ampiezza AEF è correlata all’intensità dello stimolo in modo quadratico, l’ampiezza AEP in modo, lineare. Gli AEF erano di ampiezza maggiore in risposta alla stimolazione contralaterale che in risposta alla stimolazione ipsilaterale. Gli AEP non presentano questa relazione. In un secondo esperimento gli AEF e AEP dell’emisfero destro in risposta al tono di stimolazione nell’orecchio controlaterale in questi 12 soggetti sono stati combinati con dati simili precedenti su 24 soggetti, ottenendo cosí un totale di 36 soggetti, per esaminare la comparabilità della forma dell’onadaP50 di AEP e dell’analogaP50 di AEF. Si è trovato che la latenza dellaP50 decrese in funzione dell’intensità crescente dello stimolo sia per AEF che per AEP, e che la latenza diP50 è decisamente inferiore nelle registrazioni magnetiche rispetto alle registrazioni del potenziale.
    Notes: Summary Auditory evoked magnetic fields (AEFs) and EEG auditory evoked potentials (AEPs) were recorded from left and right auditory cortical regions of 12 normal adult subjects. The magnetic sensor was a figure-eight SQUID gradiometer with a 4 cm baseline oriented so as to be maximally sensitive to a current dipole oriented normal to the Sylvian fissure. Stimuli were 100 ms long 1 kHz tone pips with a modal interstimulus interval of 700 ms delivered at sound pressure levels of 40, 60, 80 and 100 dB. AEF amplitude was found to be related to stimulus intensity in a quadratic fashion, AEP amplitude in a linear fashion. AEFs were of larger amplitude in response to contralateral as compared to ipsilateral stimulation. AEPs did not exhibit such a relationship. In a second experiment right-hemisphere AEFs and AEPs in response to contralateral ear tone stimulation in these 12 subjects were combined with similar previous data from 24 subjects, providing a total of 36 subjects, to examine the comparability of the AEPP50 wave form and the AEFP50 analog. The latency of theP50 was found to decrease as a function of increasing stimulus intensity for both AEFs and AEPs, and theP50 latency was consistently shorter in magnetic compared to potential recordings.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 484-494 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto I movimenti volontari degli arti sono preceduti da spostamenti MEG che cominciano già 1.2s prima del movimento. Questi spostamenti invertono la polarità sull’area di rappresentazione della corteccia motoria dell’arto in questione.
    Notes: Summary Voluntary limb movements are preceded by MEG shifts beginning even as early as 1.2 s before the movement. These shifts reverse polarity above the cortical motor representation area of the limb concerned.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 495-504 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Sono stati registrati i campi magnetici del cervello che precedono i movimenti autonomi delle dita della mano, del piede e della dita del piede stesso, i movimenti delle dita della mano e del piede causati da uno stimolo e la parola. Sono stati trovati lenti spostamenti dei campi magnetici con morfologia simile ai coincidenti potenziali elettrici, ma con distribuzioni molto diverse. Si discutono le deduzioni ottenute dai dati sulla localizzazione dei generatori cerebrali.
    Notes: Summary Magnetic fields of the brain were recorded preceding selfinitiated finger, foot, toe movements, stimulus-triggered finger and toe movements, and speech. Slow magnetic-field shifts were found with morphology similar to coincident electrical potentials, but with very different distributions. Inferences from the data about localization of cerebral generators were discussed.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 505-511 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Si è studiato il campo magnetico prodotto dal cervello prendendo in considerazione una varietà di eventi rari. Si riporta il carattere temporale della risposta a un raro stimolo uditivo. Il campo magnetico appare offrire un’utile nuova sonda dell’attività endogena nel cervello umano.
    Notes: Summary We have studied the magnetic field produced by the brain when attending to a variety of rare events. The temporal character of the response to a rare auditory stimulus is reported. The magnetic field appears to offer a useful new probe of endogeneous activity in the human brain.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 538-546 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; PACS. 85.25 ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Uno studio sull’attività spontanea del cervello in soggetti normali è stato eseguito con il metodo neuromagnetico. Sono stati usate 2 diverse strumentazioni per le misure magnetiche. Ambedue usavano gradiometri di second’ordine disegnati specificatamente per gli studi sul cervello: 2.9 cm di diametro, 5 cm di baseline. Uno SQUID r.f. e uno SQUID d.c. erano accoppiati ai gradiometri. I livelli di rumore misurati sono stati rispettivamente di $$40fT/\sqrt {Hz}$$ e $$25fT/\sqrt {Hz}$$ . In alcuni soggetti sono state effettuate mappe di campi magnetici generati dall’attività spontanea del cervello. Le mappe dell’ampiezza media dei segnali del ritmo α hanno mostrato 2 massimi dell’attività su 2 regioni simmetriche dello scalpo. Comunque, malgrado una generale simmetria fra gli emisferi, la complessità delle mappe misurate suggerisce una corrispondente complessità dei generatori responsabili dell’attività α.
    Notes: Summary An investigation of the spontaneous brain activity from normal subjects has been carried out by means of the neuromagnetic method. Two different systems were used for magnetic measurements. Both used 2nd-order gradiometers specifically designed for brain studies: 2.9 cm diameter, 5 cm baseline. A r.f. SQUID and a d.c. SQUID were coupled to the gradiometers. The measured noise levels are $$40fT/\sqrt {Hz}$$ and $$25fT/\sqrt {Hz}$$ , respectively. Thorough magnetic mapping of the spontaneous activity was performed on a few subjects. By mapping the average amplitude of the α-rhythm signals two maxima of activity over two symmetric regions of the scalp were clearly observed. Despite a general symmetry between hemispheres, however, the complexity of the measured maps suggests a corresponding complexity of the generators responsible for α-activity.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 214-223 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; PACS. 85.25 ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si discutono magnetometri del tipo del flussometro elettronico e di risonanza (precisione libera, pompata otticamente) che possono in qualche caso sostituire il magnetometro SQUID. Si descrivono i princípi di funzionamento, la sensibilità, l’intervallo dinamico e la risposta di frequenza. Si dà un accenno riguardo l’applicazione di questi magnetometri nelle misurazioni biomagnetiche.
    Notes: Summary Flux gate and resonance type of magnetometers (free precession, optically pumped), which can in some cases replace the SQUID magnetometer, are discussed. The principles of operation, sensitivity, dynamical range and frequency response are described. The application of these magnetometers for biomagnetic measurements is mentioned.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 255-265 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto È stata sfruttata la risoluzione spaziale del sensore magnetico per fornire stime numeriche del contributo atriale ai campi magnetici registrati esattamente prima della depolarizzazione ventricolare. Si trova che il contributo è piccolo, e questo rafforza l’interpretazione originale secondo la quale questi campi derivano principalmente dal sistema di conduzione del cuore.
    Notes: Summary We have exploited the spatial resolution of the magnetic sensor to provide numerical estimates of the atrial contribution to magnetic fields recorded just prior to ventricular depolarization. The contribution is found to be small, strenghening our original interpretation that such fields originate mostly in the conduction system of the heart.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 291-300 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Si presentano i risultati preliminari ottenuti costruendo mediante computer mappe di distribuzione di campo magnetico sulla base di registrazioni ad alta risoluzione effettuate con magnetometro superconduttore. La procedura è stata applicata per esaminare i MCG di 16 pazienti affetti da pregresso infarto del miocardio. Sulla base di questa elaborazione è stato possibile dividere i pazienti in due classi, una delle quali contiene tutti i pazienti con depolarizzazioni tardive.
    Notes: Summary A possible clinical application of a high-resolution magnetic isofield contour mapping technique in cardiography is discussed. Preliminary results are presented in applying this technique to patients with recent myocardial infarction. The patients could be divided into two classes; one of them contains patients with electrical late potentials as a subclass.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 512-516 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Si presentano le prime misurazioni del campo magnetico prodotto da correnti di azione che si propagano lungo l’assone singolo di un nervo gigante. Questi dati sono stati ottenuti con un trasduttore a bobina toroidale e un amplificatore o semiconduttore a temperatura ambiente.
    Notes: Summary We present the first measurements of the magnetic field produced by action currents propagating along a single giant nerve axon. These data were obtained with a toroidal pick-up coil and a room temperature semiconductor amplifier.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 517-537 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Finora la magnetoencefalografia spontanea (MEG) in soggetti normali e patologici non è stata investigata a fondo. Si conoscono pochissimi contributi in questo campo. A parte il lavoro del gruppo di biomagnetismo di Roma, il solo contributo clinico finora è stato quello di Hughes e collaboratori che era abbastanza limitato nel numero e nella scelta dei soggetti studiati. La nostra esperienza condotta fin dal 1980 su un gran numero di casi (principalmente epilessie focali) mostra che il MEG può evidenziare attività significative anche se non sono presenti anormalità EEG; esso ha inoltre una risoluzione spaziale maggiore rispetto all’EEG. I foci epilettici mostrano un’area limitata di attività massima. Finora non è stata osservata nessuna evidenza sperimentale di una differente distribuzione delle ampiezze del campo sullo scalpo. La risoluzione spaziale del MEG riguarda anche la possibilità di risolvere la morfologia dei segnali EEG (per esempio onde aguzze EEG risolte in gruppi di spikes dal MEG) o di separare topograficamente le anormalità EEG mescolate e non ben localizzate (per esempio, attività delta ed epilettiche mescolate nell’EEG e discriminate nel MEG). I migliori risultati si osservano quando la localizzazione è nella corteccia esterna. Dopo una descrizione del materiale studiato, si sottolinea l’importanza dei risultati ottenuti per la prima volta in casi di epilessie focali.
    Notes: Summary So far spontaneous magnetoencephalography (MEG) in normal and pathological subjects has not been deeply investigated. Very few contributions in this field are available. Aside from the work of the Rome biomagnetic group in this field, the only clinical contribution up to now has been that of Hughes and co-workers which was rather limited in the number and in the selection of subjects investigated. Our experience, carried out since 1980 on a large number of cases—mainly focal epilepsies— shows that the MEG may evidence significant activities even if EEG abnormalities are not present and has a higher spatial resolution with respect to the EEG. Epileptic foci show a limited area of maximal activity. So far no experimental evidence of a different distribution of field amplitude over the scalp has been observed. The spatial resolution of the MEG also regards the possibility of resolving the morphology of EEG signals (for instance, EEG sharp waves resolved into groups of spikes by MEG) or topographically separate EEG abnormalities mixed up and not well localized (for instance, delta and epileptic activities mixed up in the EEG, but differently in the MEG). The best results are observed when the localization is in the outer cortex. After a description of the material studied, the importance of the results obtained for the first time in cases of focal epilepsies is outlined.
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    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 547-557 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
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    Topics: Physics
    Description / Table of Contents: Riassunto Durante l’ultimo anno gli autori hanno condotto una ricerca sistematica su un gran numero di soggetti patologici registrando simultaneamente l’EEG e il MEG. La presente versione del nostro apparato sperimentale permette di effettuare misure MEG con un solo sensore magnetico, impedendo la rilevazione simultanea di attività MEG su punti differenti della testa. Ciò ha condotto gli autori a concentrarsi sulle epilessie focali. Fin dalle prime misure il sensore magnetico ha dimostrato un notevole potere localizzante, rafforzando l’interesse per la localizzazione in casi patologici. In questo lavoro si riportano risultati che sembrano confermare la straordìnaria capacità delle misure MEG nel localizzare sorgenti di attività cerebrali patologiche in casi di epilessie focali.
    Notes: Summary During the last year the authors have been carrying out a systematic investigation on a large number of pathological subjects simultaneously recording the EEG and the MEG. The present version of our experimental apparatus allows MEG measurements with only one magnetic detector, thus preventing the detection of simultaneous MEG activities over different points of the head. This has led the authors to concentrate upon focal epilepsies. Since the first measurements a remarkable localizing power was shown by the magnetic detector, thus strengthening the interest in pathological localization. In this contribution we report results which seem to confirm the extraordinary capability of MEG measurements to localize sources of pathological brain activities in cases of focal epilepsies.
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    Applied physics 27 (1982), S. 39-42 
    ISSN: 1432-0649
    Keywords: 07.65 ; 35
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    Topics: Physics
    Notes: Abstract To use the sensitivity and the measurement accuracy of the optothermal detector (OT) better for linear absorption detection, a theory of the signal behaviour, worth for the most important range of application, is developed and compared with experimental data. By means of the example of CO2-laser light absorption by ammonia, containing two different nitrogen isotopes, the possibility of correcting measured values to get more exact information of the absorption behaviour is shown. The limits of error, as well as the reproducibility of the measurments could be kept in a range of about 1%.
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    Applied physics 27 (1982), S. 83-91 
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    Keywords: 42.65 ; 06 ; 35 ; 07.65
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    Notes: Abstract The space-time properties of the correlator of the light intensities scattered from resonant atoms are studied. It is shown that in measuring such a correlator by the method of optical shifts, an appreciable contribution appears from the anomalous correlator of the scattered field amplitudes. It is simple to observe this correlator in the field of a standing wave by measuring the correlation of oppositely scattered rays. The spectral and polarization properties of such a correlator are studied. Its investigation is of interest for high-resolution spectroscopy because it allows information to be obtained on the natural width of a line in conditions of strong Doppler broadening. It is important to stress that this is possible in a linear approximation with respect to the strength of the external field in contrast to the methods of laser spectroscopy based on nonlinear effects.
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    ISSN: 1432-0649
    Keywords: 42.60 ; 07.65
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    Notes: Abstract A supersonic molecular beam, pulsed laser and time-of-flight mass spectrometer are arranged together in order to study photo- and auto-ionization, two-photon-ionization and fragmentation processes of alkali clusters as a function of the laser wavelength. In spite of an unfavourable duty cycle, however, the apparatus reaches a considerably higher sensitivity than cw experiments. Alkali clustersM n (n≲21) have been observed and investigated. The well resolved TOF mass spectra are commonly accompanied by significant and broad signals of metastable ions, a phenomenon which cannot be observed by quadrupole mass spectrometry. ParticlesM n (n≲4) have been investigated by twophoton ionization using two different laser wavelengths. Several new electronic transitions for Na3 are found; commonly, however, the excitation and ionization channels are accompanied by strong fragmentation processes. The fragment patterns are very sensitively dependent upon the laser wavelength even when working near the ionization threshold. The results are a strong indication, that the peak intensities of cluster mass spectra cannot easily be related to the intensity distribution of the neutral cluster beam.
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    Applied physics 29 (1982), S. 89-92 
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    Notes: Abstract An attempt is described to confine ions, created externally and accelerated to some energy, in an rf quadrupole trap. 4 keV Ba+ ions were stopped on a Ni foil, placed in an aperture of one trap electrode. The Ba then was evaporated from the heated foil and ionized by electron impact. At background pressure of about 10−5 mbar of various light buffer gases (He, H2, N2), the trap was filled once with 105 ions, at a minimum primary ion number of 1010. The storage time was 10 min. From the data obtained the possibility of spectroseopic experiments on rare isotopes, created with accelerators or nuclear reactors, is discussed.
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    Applied physics 27 (1982), S. 153-156 
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    Keywords: 33 ; 42.80 ; 07.65
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    Notes: Abstract A sub-Doppler spectroscopic technique involving the detection of vibrational energy transfer in excited molecules with selected velocity components at a microphone diaphragm is demonstrated. The technique is applied to the investigation of thev 3 R(16) transition in HCN and the results compared with a previously derived theoretical model.
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    Applied physics 28 (1982), S. 319-326 
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    Keywords: 07.60 ; 07.65 ; 42.60
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    Notes: Abstract A sync-pumped cw dye laser system has been used to produce subpicosecond pulses. Pulses as short as 0.7 ps, assuming a single-sided exponential pulse shape, were observed. A set of experiments was performed to investigate the origin and effects of noise in the sync-pumped system. A digital and an analog feedback loop have been designed to optimize the pulse width. The noise has been lowered by 10 dB for frequencies up to 10 kHz; long-term drift is also controlled by this method. A four-stage dye laser amplifier, pumped by a Nd:YAG laser which operates at a 10-Hz repetition rate, is synchronized electronically to the dye-laser picosecond pulses. A gain of 3×106 has been achieved.
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    Applied physics 29 (1982), S. 279-285 
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    Notes: Abstract The minimum absorption detectable by a tunable diode laser spectrometer utilising harmonic techniques is often limited by interference fringes generated by scattered light. The sensitivity of the spectrometer to absorption can be increased by applying a jitter modulation. In this paper, the theory of harmonic response for single- and two-tone modulation over optical fringes and Lorentzian absorption lines is developed and compared to experimental measurements. A simple analytic expression for the two-tone harmonic line shape is derived. This expression provides a physical understanding of the effects of the second modulation, and a means to unravel the effects of the second modulation on the linewidth and line shape. For a specific choice of the jitter frequency and phase, it is possible to simultaneously minimise the fringe signal and increase the harmonic absorption signal. The results of this investigation are applicable to trace gas detection using tunable diode lasers, and to other areas of spectroscopy and magnetic resonance where harmonic techniques are used.
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    Applied physics 29 (1982), S. 213-218 
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    Notes: Abstract The population lifetimes of the symmetric CH2-stretching mode of several methylene halides were measured after infrared excitation by spontaneous anti-Stokes Raman scattering of delayed picosecond probe pulses. Data ranging from 6.5 to 45 ps are reported. The results give evidence for vibrational energy transfer via anharmonic coupling to neighbouring vibrational combination bands and overtones.
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  • 65
    ISSN: 1573-6881
    Keywords: Respiratory chain ; ATP synthesis ; mitochondria ; ubiquinone ; Saccharomyces cerevisiae ; cytochrome oxidase
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    Topics: Biology , Chemistry and Pharmacology , Physics
    Notes: Abstract Mitochondria, isolated from the ubiquinone-deficient nuclear mutant ofSaccharomyces cerevisiae E3-24, are practically unable to oxidize exogenous substrates. Respiratory activity, coupled to ATP synthesis, can, however, be reconstituted by the simple addition of ethanolic solutions of ubiquinones. A minimal length of the isoprenoid side chain (≥3) was required for the restoration. Saturation of the reconstitution required a large amount of exogeneous ubiquinone, in excess over the normal content present in the mitochondria of the wild type strain. A similar pattern of reconstituted activities could be also obtained using sonicated inverted particles. Mitochondria and sonicated particles are also able to carry out a dye-mediated electron flow coupled to ATP synthesis in the absence of added ubiquinone, using ascorbate or succinate as electron donor. This demonstrates that the energy conserving mechanism at the third coupling site of the respiratory chain is fully independent of the presence of the large mobile pool of ubiquinone in the membrane.
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    Applied physics 26 (1981), S. 203-210 
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    Notes: Abstract A series of experiments are carried out by current modulating a tunable diode laser, and slowly ramping the wavelength to scan weak absorption lines in gases at pressures ranging from 2 to 60 Torr. A lock-in amplifier detects the second harmonic (2f) of the modulation frequency, and the experimental 2f signals are compared with theory. Detailed measurements are made on Lorentzian, Voigt, and Gaussian line profiles, over a wide range of modulation amplitudes. Excellent agreement between experiment and calculation is obtained in all cases. This quantitative understanding enables one to derive true lineshapes and linewidths of very weak absorption lines from measurements of 2f lineshapes only. Results are applicable to trace gas detection using tunable diode lasers, and to other areas of spectroscopy and magnetic resonance where harmonic detection techniques are routinely employed to monitor weak signals.
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    Applied physics 24 (1981), S. 11-12 
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    Notes: Abstract Experimental observation of optical Ramsey interference in saturated absorption of methane in a low-pressure gas cell with three spacially separated laser beams at 3.39 μm is reported.
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    Applied physics 24 (1981), S. 147-150 
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    Notes: Abstract A recent holographic technique makes it possible to manufacture a new kind of grating, the “Fourier grating”, whose profile is given by a superposition of a fundamental and a finite number of harmonics. A local theoretical optimization shows that this type of grating can have an efficiency better, than that of the echelette, for a broad wavelength range. In this paper, we show the validity of this theoretical prediction by an experimental verification in the microwave region.
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    Applied physics 25 (1981), S. 221-229 
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    Notes: Abstract Photoacoustic cells consisting of two chambers connected by a long narrow tube were studied at room temperature. Amplitude and phase angle of the PA signal were measured as a function of chopping frequency, tube length and buffer gas. Multipleresonance spectra were observed which can be interpreted quantitatively by a modified model of the acoustic Helmholtz resonator. The theoretical description is based on the analogy to the electrical transmission line theory.
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    Applied physics 23 (1980), S. 407-409 
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    Notes: Abstract We report about possibilities of application of the optothermal detector (OT) for sub-Doppler spectroscopy experiments. Investigating transitions of SF6 in the 10 μm region we demonstrate two variants of obtaining high-frequency resolution-using a standing or a travelling wave.
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    Applied physics 21 (1980), S. 173-180 
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    Notes: Abstract Recent developments of tunable IR compressed-H2 and liquid-N2 Raman Lasers as well as resonantly pumped NH3 lasers are reviewed. Emphasis is placed on research carried out at the Quantum Radiophysics Laboratory of the Lebedev Physical Institute in Moscow.
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    Notes: Abstract The application of the high-pressure chamber with a pressure transmitting medium (liquid at room temperature) to diode-laser tuning was found to be a useful method for high-resolution spectroscopy. Ammonia absorbtion spectra in the 10 μm region were recorded with a resolution approaching the Doppler limit.
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    Applied physics 22 (1980), S. 245-250 
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    Notes: Abstract The results of fluorescence detection of single Na atoms in atomic beams have been presented. It has been shown that, in recording single atoms via the fluorescence signal from the photoelectron of thek〉1 atom, it is possible to achieve extremely high selectivity (S≃1020) of detection of these atoms against a great number of other atoms. The probability of recording the atom is slightly decreased.
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    Applied physics 22 (1980), S. 251-256 
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    Notes: Abstract The input format of fast digital correlators, such as used in photon correlation or recurrence rate correlation, is often exceeded by input signals, if high count rates coincide with sample times of the order of several hundred nanoseconds or more. Clipping, random clipping, and scaling are well known methods to reduce such signals appropriately. We discuss these procedures with special attention to noise performance possible errors introduced into the correlogram. Generalizations from single to multi-bit correlators are presented with a thorough discussion of random preset scaling, a new process suitable for multi-bit correlation of signals with arbitrary statistics. Furthermore we describe a new additional preprocessor which offers significant decrease of quantization noise, if constant background contributions are present in the signal. Though demonstrated on optical measurements, the methods treated in this paper generally apply, whenever the format of digital data has to be reduced prior to correlation.
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    Notes: Abstract The noise characteristic of available laser sources limits the sensitivity of saturated absorption spectroscopy. Time averaging is one method to improve the signal-to-noise ratio. A computer controlled dye-laser spectrometer is described which has the capability to scan several times any selected frequency range with an absolute accuracy of ±200 kHz. The sensitivity of this system is demonstrated by measuring the isotope shift of the low abundant38Ar and by detecting a weak83Kr-hyperfine component.
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    Applied physics 21 (1980), S. 181-189 
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    Notes: Abstract Refined values for molecular constants of14NH3 and less precise values for those of15NH3 and14NH2D were obtained with laser Stark spectroscopy.
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    Applied physics 22 (1980), S. 1-9 
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    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract In this paper we study the optical Ramsey resonance signal of two-level molecules in three separated fields consisting of one standing wave and two traveling waves of opposite directions with each other. Their separations and phase differences are given by a corner reflector. The transition probability of a molecule that traverses the three interaction regions is calculated by using an optical Bloch vector formalism. It is then integrated over distributions of molecular velocities and positions to evaluate the signal observed with a gas cell. The result is applied to compute the optical Ramsey resonance signal in the absorption line of CH4 at 3.39 μm. Variations of the Ramsey resonance lineshape and the intensity with the gas pressure and the field intensity are obtained.
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  • 78
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 22 (1980), S. 433-437 
    ISSN: 1432-0630
    Keywords: 07.65
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Generation of backward photon echoes and proposed backward optical free induction decays is discussed in detail. Separation of the signals from excitation pulses by propagation and polarization directions suggests a new field of picosecond experiments.
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  • 79
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 23 (1980), S. 319-326 
    ISSN: 1432-0630
    Keywords: 06 ; 07.65 ; 42.80
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract We report a new design for an acoustically resonant spectrophone well suited for intracavity operation with widely tunable lasers. Operation with Brewster angle windows or in a windowless mode is possible, and high quality factors (560 and 509, respectively) are achieved. Windowless operation permits continuous monitoring of ambient air. We discuss factors limiting the sensitivity, ∼10−7 cm−1, and present a double chopping scheme capable of significantly reducing the acoustical background encountered in windowless operation. The sensitivity of the spectrophone's performance to misalignment is also examined.
    Type of Medium: Electronic Resource
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  • 80
    ISSN: 1432-0630
    Keywords: 07.65 ; 34
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Novel techniques to observe coherent transients are successfully demonstrated on microwave transitions of NH3, H2O, OCS, and O2. The relaxation rate constants in thev 2 excited state of NH3 are obtained by infrared experiments.
    Type of Medium: Electronic Resource
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