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  • Chemistry  (8,893)
  • Organic Chemistry  (3,064)
  • General Chemistry  (2,735)
  • Life Sciences (General)  (2,422)
  • Cell & Developmental Biology
  • Instrumentation and Photography
  • Limnology
  • 2020-2024  (52)
  • 2000-2004  (4,064)
  • 1945-1949  (4,115)
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  • 1
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    EDP SCIENCES
    Publication Date: 2024-04-05
    Description: Chemistry
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 2
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    EDP SCIENCES
    Publication Date: 2024-04-05
    Description: Chemistry
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 3
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    EDP SCIENCES
    Publication Date: 2024-04-07
    Description: Chemistry
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 4
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-05
    Description: Chilean Patagonia, located at the southwestern tip of South America, is one of the last regions on earth where highly intact environments predominate. With a coastline that extends along some 100,000 km of fjords, channels, and islands, it has one of the world´s most extensive marine-terrestrial interfaces. Local place-based and Indigenous cultures and management practices are a vital presence across the region, while the long and rich history of conservation efforts have resulted in officially protected areas covering over 50% of the land and 41% of the coastal-marine area. However, Chilean Patagonia is increasingly facing anthropogenic pressures associated with increased infrastructure and access, salmon aquaculture, extractive industries, and the spread of invasive exotic species. Despite widespread recognition that Chilean Patagonia represents a unique global reservoir of socio-natural heritage, to date there has been no region-wide assessment of the scientific evidence of the conservation status of its ecosystems or the priorities for their effective conservation. Conservation in Chilean Patagonia: Assessing the state of knowledge, opportunities, and challenges is the first book to gather and synthesize the available scientific and socio-environmental information related to Patagonian conservation. It presents the collaborative work of 68 researchers and local experts, representing a range of specialties and perspectives, including: biology, ecology, socio-ecology, fisheries, aquaculture, anthropology, economics, geography, tourism, cryosphere, oceanography, climate and global change. The book’s 18 chapters focus on the status of key ecosystems and conservation tools, and provide recommendations toward the construction of a renewed, inclusive, and integrated conservation agenda for the Chilean Patagonian region. It provides an essential primer for anyone interested in the future of this ecologically vital region, as well as lessons on interdisciplinary collaboration and integrated analysis of conservation issues useful for conservation practitioners and scholars. This is an open access book. This book is a translation of an original Spanish edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Keywords: Ecology ; Limnology ; Oceanography ; Biodiversity ; Marine-terrestrial Interface ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNK Conservation of the environment ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RB Earth sciences::RBK Hydrology and the hydrosphere::RBKC Oceanography (seas and oceans) ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RG Geography::RGM Biogeography ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNC Applied ecology::RNCB Biodiversity
    Language: English
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  • 5
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-01-16
    Description: Chilean Patagonia, located at the southwestern tip of South America, is one of the last regions on earth where highly intact environments predominate. With a coastline that extends along some 100,000 km of fjords, channels, and islands, it has one of the world´s most extensive marine-terrestrial interfaces. Local place-based and Indigenous cultures and management practices are a vital presence across the region, while the long and rich history of conservation efforts have resulted in officially protected areas covering over 50% of the land and 41% of the coastal-marine area. However, Chilean Patagonia is increasingly facing anthropogenic pressures associated with increased infrastructure and access, salmon aquaculture, extractive industries, and the spread of invasive exotic species. Despite widespread recognition that Chilean Patagonia represents a unique global reservoir of socio-natural heritage, to date there has been no region-wide assessment of the scientific evidence of the conservation status of its ecosystems or the priorities for their effective conservation. Conservation in Chilean Patagonia: Assessing the state of knowledge, opportunities, and challenges is the first book to gather and synthesize the available scientific and socio-environmental information related to Patagonian conservation. It presents the collaborative work of 68 researchers and local experts, representing a range of specialties and perspectives, including: biology, ecology, socio-ecology, fisheries, aquaculture, anthropology, economics, geography, tourism, cryosphere, oceanography, climate and global change. The book’s 18 chapters focus on the status of key ecosystems and conservation tools, and provide recommendations toward the construction of a renewed, inclusive, and integrated conservation agenda for the Chilean Patagonian region. It provides an essential primer for anyone interested in the future of this ecologically vital region, as well as lessons on interdisciplinary collaboration and integrated analysis of conservation issues useful for conservation practitioners and scholars. This is an open access book. This book is a translation of an original Spanish edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Keywords: Ecology ; Limnology ; Oceanography ; Biodiversity ; Marine-terrestrial Interface ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNK Conservation of the environment ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography::RGM Biogeography ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNC Applied ecology::RNCB Biodiversity
    Language: English
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  • 6
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    EDP SCIENCES
    Publication Date: 2024-04-05
    Description: Chemistry
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 7
    Publication Date: 2024-04-05
    Description: Chemistry
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 8
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    EDP SCIENCES
    Publication Date: 2024-04-08
    Description: Chemistry
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 9
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    EDP SCIENCES
    Publication Date: 2024-04-05
    Description: Chemistry;Materials science
    Keywords: Chemistry ; Materials science ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 10
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    EDP SCIENCES
    Publication Date: 2024-04-05
    Description: Chemistry
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: French
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  • 11
    Publication Date: 2024-04-22
    Description: A preliminary inventory of the composition of zooplancktonic species found in Bayano Lake, between February and September 1981 revealed that there are seven species of Rotifera, five Cladocera, two Copepoda, one Ostracoda and larvae of Macrobrachium (Decapoda) and Chaoborus (Diptera). The composition, abundance and horizontal and monthly distribution of the most important zooplanktonic groups found in Bayano Lake are here presented.
    Description: Published
    Description: Refereed
    Keywords: Limonology ; Abundancia ; Vertical distribution ; Limnology ; Composición
    Repository Name: AquaDocs
    Type: Journal Contribution
    Format: pp.17-24
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  • 12
    Publication Date: 2024-05-20
    Description: To ensure the long-term sustainable use of African Great Lakes (AGL), and to better understand the functioning of these ecosystems, authorities, managers and scientists need regularly collected scientific data and information of key environmental indicators over multi-years to make informed decisions. Monitoring is regularly conducted at some sites across AGL; while at others sites, it is rare or conducted irregularly in response to sporadic funding or short-term projects/studies. Managers and scientists working on the AGL thus often lack critical long-term data to evaluate and gauge ongoing changes. Hence, we propose a multi-lake approach to harmonize data collection modalities for better understanding of regional and global environmental impacts on AGL. Climate variability has had strong impacts on all AGL in the recent past. Although these lakes have specific characteristics, their limnological cycles show many similarities. Because different anthropogenic pressures take place at the different AGL, harmonized multilake monitoring will provide comparable data to address the main drivers of concern (climate versus regional anthropogenic impact). To realize harmonized long-term multi-lake monitoring, the approach will need: (1) support of a wide community of researchers and managers; (2) political goodwill towards a common goal for such monitoring; and (3) sufficient capacity (e.g., institutional, financial, human and logistic resources) for its implementation. This paper presents an assessment of the state of monitoring the AGL and possible approaches to realize a long-term, multi-lake harmonized monitoring strategy. Key parameters are proposed. The support of national and regional authorities is necessary as each AGL crosses international boundaries.
    Description: Published
    Description: 101988
    Description: JCR Journal
    Keywords: Fisheries ; Limnology ; Pollution ; Biodiversity ; Climate change ; Erosion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 13
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Mineralogy includes thirteen chapters that discuss the methodology of specific mineralogical methods, the composition of minerals from different igneous rocks, and the composition of minerals from different sedimentary rocks.It contains detailed mineralogical studies from Africa, Asia, and Europe. Chapters present different scientific mineralogical methods and detailed descriptions of minerals from different magmatic and sedimentary rocks.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNV Chemistry of minerals, crystals and gems
    Language: English
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  • 14
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Benzimidazole is a comprehensive survey of the known and new methods of benzimidazole synthesis, the spectral and theoretical aspects of existing benzimidazole derivatives, and the anticancer properties of a new class of benzimidazole derivatives. This book examines aspects and newer mechanisms of benzimidazoles containing heterocyclic moiety. Chapters report on anticancer properties of benzimidazole derivatives, novel methods of synthesis of benzimidazoles, versatile nature of the benzimidazoles, spectral and theoretical studies of benzimidazole derivatives, and medicinal importance and pharmacological aspects of benzimidazole derivatives.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 15
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Green Chemistry - New Perspectives is at the frontiers of this continuously evolving interdisciplinary science, and publishes research that attempts to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The book covers all aspects of green chemistry, including chemical synthesis, nano synthesis, eco-friendly processes, biomass, extraction techniques, environmental remediation, and energy, making it a unique reference resource. This will continue to encourage scientists around the world to develop novel synthetic methods or improve the existing ones to circumvent some of the problems and favours all aspects of green chemistry. This book is intended for academia, professionals, scientists, as well as graduate and undergraduate students without any geographical limitations.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 16
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book consists of several selected chapters on important subjects in modern high-performance liquid chromatography (HPLC) and ultra-performance liquid chromatography (UPLC). The content addresses aspects related to both improvements in the mainstream HPLC/UPLC technology and utilization, as well as developments of exploratory new materials and equipment. The book presents useful details about the presented subjects as well as describes new applications and/or relevant case studies for each subject. It is addressed to a large audience of analytical chemists involved in separation science. Each chapter is authored by scientists with considerable field and academic experience.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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  • 17
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Recent Advances in Chemical Kinetics provides a comprehensive overview of several types of chemical reactions. It includes six chapters that discuss solvent catalysis, customized flow reactors, p-conjugation in kinetics, kinetics of autoxidation, molecular chameleon for cations and anions, and internal clocks of atoms.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
    Language: English
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  • 18
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Redox reactions are involved in biochemistry, energy, corrosion, and much more. In both biology and electrochemistry, the redox reaction is complex and varied. For example, redox shuttles in supercapacitors show aspects of molecular electrochemistry applied to electrode porosity. In pseudocapacitors, the formalism associated with their electrochemical response requires investigation and formalism. Similarly, the simple definition of redox potential opens fundamental questions about its measurement in solutions without supporting salts. This book illustrates the variety of redox reactions in its examination of the importance of redox molecules in the development of new electrical energy storage devices.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
    Language: English
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  • 19
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: We are living in a critical time, both for humanity and the planet, which has led us to look for more sustainable formulas to interact with the environment. One of the important changes in the design and operation of chemical processes is the search for environmentally friendly technologies. Supercritical carbon dioxide has been revealed as a promising environmentally friendly solvent that is energy efficient, selective and capable of reducing waste, making it a promising alternative to conventional organic solvents. However, reliable and versatile mathematical models of phase equilibrium thermodynamics are needed for the use of supercritical carbon dioxide in process design and viability studies. This book reviews experimental procedures for obtaining high-pressure phase equilibria data and describes the phase diagrams of binary mixtures and some thermodynamic models capable of determining the conditions of phase equilibria at high pressures. These concepts are applied to the components of the transesterification reaction of rac-2-pentanol with a vinyl ester, which is important in the pharmaceutical industry because (S)-2-pentanol can be obtained as a reaction product. This product is a key intermediate in the synthesis of drugs against Alzheimer’s disease.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
    Language: English
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  • 20
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: In recent decades, artificial porous structures have attracted increasing enthusiasm from researchers inspired by the fascinating molecular pores in nature and their unique biological functions. Although substantial achievements in porous materials have been realized, the construction of topologically designed pores is still challenging. Recently, the emergence of covalent organic frameworks (COFs), which are constructed based on organic and polymer chemistry, has made it possible to design artificial pores with controlled pore size, topology and interface properties. COFs are crystalline porous materials constructed by the precise reticulation of organic building blocks via dynamic covalent bonds. Distinct from non-covalent interactions which tend to produce isostructures, covalent bonds enable accurate pore design owing to their predetermined reaction pathways. In addition, the appropriate polycondensation of organic building units enables the formation of extended two-dimensional (2D) and three-dimensional (3D) polymer architectures with periodically ordered skeletons and well-defined pores. With their large surface area, tailorable structures, and tunable chemistry, COFs are regarded as potentially superior candidates for various applications including catalysis, energy storage and conversion, mass transport and biotechnology. This book examines the historic achievement of COFs, providing clear and comprehensive guidance for researchers on their structural design, synthetic protocols and functional exploration.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 21
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Fluoride covers a continuum of topics that are frequently studied in the broad area of fluoride (F) research. It provides an overview of the primary sources of environmental fluoride in typical high-fluoride environments and demonstrates the transitions and transformations that emerge and culminate in hydro-geochemical interactions that result in fluoride-fouling of large portions of the world’s water and agricultural resources. This way, the book pinpoints the connection between F enrichment of water sources and the prevalence of endemic fluorosis in certain areas of the world. In order to contribute to a better understanding of the global fluoride problem, new fluoride detection and quantification technologies are proposed with an in-depth analysis of emerging trends in the use of portable user-friendly devices in point-of-use measurements of water fluoride. This has been presented against the backdrop of a robust overview of traditional fluoride quantification methodologies that are still in wide application among the scientific communities. In addressing fluoride toxicities, which are not limited to dental and skeletal dilapidations, the authors have explored the role of natural antioxidants in ameliorating physiological fluoride-induced noxious effects in mammalian systems. Nonetheless, since community dependence on high-fluoride water due to a lack of alternative clean water sources remains to be the principal pathway of human fluoride over-exposure, a review chapter on F mitigation techniques applied all over the world is incorporated aiming at providing a succinct overview of water defluoridation techniques and strategies being used to combat the impacts of human F overexposure around the globe. Since every cloud has a silvery lining, the possibility of using ammonium fluorides as a novel reagent in mineral processing has been considered convenient industrial fluorinating agents, which present the possibility of complete regeneration that is not afforded by the reagents presently used in decomposing silicon component of the ores.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
    Language: English
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  • 22
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book discusses the chemistry and applications of pyridine derivatives. The library of pyridine derivatives is growing steadily with numerous synthetic analogues already described and the identification of new, naturally occurring pyridine-based compounds. The book includes ten chapters organized into two parts. The first part focuses on the numerous types of reactions that arise from pyridine derivatives. The second part examines the pharmaceutical applications of pyridine derivatives as well as their usefulness as sensors for metal cations and extracting agents for platinum group metals.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 23
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The book discusses multiple issues associated with modern dosimetry in physics and treatment planning and how investigators from diverse world centers and institutions approach problem-solving in these important areas. It examines topics including pretreatment validation and factors affecting reference dosimetry. It also addresses unique issues affecting pediatric populations as well as the modern role of thermoluminescence validation. Several chapters discuss intensity modulation, including defining modern problems associated with both treatment planning and the definition of tumor and normal tissue contours. Furthermore, the book examines the role of imaging as both a vehicle to define tumor targets and normal tissue as well as a tool for dose validation.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRL Nuclear chemistry, photochemistry and radiation
    Language: English
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  • 24
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The book comprises 14 chapters covering all the issues related to water desalination. These chapters emphasize the relationship between problems encountered with the use of feed water, the processes developed to address them, the operation of the required plants and solutions actually implemented. This compendium will assist designers, engineers and investigators to select the process and plant configuration that are most appropriate for the particular feed water to be used, for the geographic region considered, as well as for the characteristics required of the treated water produced. This survey offers a comprehensive, hierarchical and logical assessment of the entire desalination industry. It starts with the worldwide scarcity of water and energy, continues with the thermal - and membrane-based processes and, finally, presents the design and operation of large and small desalination plants. As such, it covers all the scientific, technological and economical aspects of this critical industry, not disregarding its environmental and social points of view. One of InTech's books has received widespread praise across a number of key publications. Desalination, Trends and Technologies (Ed. Schorr, M. 2011) has been reviewed in Corrosion Engineering, Science & Technology – the official magazine for the Institute of Materials, Minerals & Mining, and Taylor & Francis's Desalination Publications. Praised for its “multi-faceted content [which] contributes to enrich it,” and described as “an essential companion...[that] enables the reader to gain a deeper understanding of the desalination industry,” this book is testament to the quality improvements we have been striving towards over the last twelve months.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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  • 25
    Publication Date: 2024-04-05
    Description: The Global Methane Initiative (GMI) is a voluntary international partnership that promotes methane recovery and reuse activities in developing and transition economies. The U.S. Department of State requested an evaluation of the activities and outcomes supported in whole or in part by its contributions to GMI to gauge its value added to the program.
    Keywords: Physics ; Environmental Science ; Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RB Earth sciences::RBP Meteorology and climatology
    Language: English
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  • 26
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Progress in agricultural, biomedical and industrial applications' is a compilation of recent advances and developments in gas chromatography and its applications. The chapters cover various aspects of applications ranging from basic biological, biomedical applications to industrial applications. Book chapters analyze new developments in chromatographic columns, microextraction techniques, derivatisation techniques and pyrolysis techniques. The book also includes several aspects of basic chromatography techniques and is suitable for both young and advanced chromatographers. It includes some new developments in chromatography such as multidimensional chromatography, inverse chromatography and some discussions on two-dimensional chromatography. The topics covered include analysis of volatiles, toxicants, indoor air, petroleum hydrocarbons, organometallic compounds and natural products. The chapters were written by experts from various fields and clearly assisted by simple diagrams and tables. This book is highly recommended for chemists as well as non-chemists working in gas chromatography.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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  • 27
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book discusses electrocatalysis and electrocatalysts for energy, water electrolysis, water treatment, CO2 conversion, and green chemistry. It reviews various electrocatalysts and their properties and electrochemical performances. The first section of the book covers topics in direct alcohol fuel cells including Pt-based electrocatalysts as non-carbon electrode support materials and the development of electrocatalysts for direct methanol fuel cells. The second section of the book covers various topics in electrocatalysis and electrocatalysts for a cleaner environment, including electrocatalysts for the conversion of CO2 to valuable products and SYNGAS, electrocatalysts for water electrolysis, and much more.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
    Language: English
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  • 28
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Surfactants are ubiquitous and have applications in diverse areas, including food, cosmetics, detergents, lubricants, enhanced oil recovery (EOR), and targeted drug delivery systems. Their wide diversity of applications owes to their unique structure, namely, a hydrophilic and a hydrophobic group present in the same molecule. Although most surfactants used industrially are synthetic, there is a growing need for natural surfactants, as the latter is obtainable from renewable sources and are less toxic and highly biodegradable in contrast to their synthetic counterparts. This book is a compilation of interesting articles by various experts that cover various applications of both synthetic and natural surfactants.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRC Colloid chemistry
    Language: English
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  • 29
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The chemical sensor plays an essential role in the fields of environmental conservation and monitoring, disaster and disease prevention, and industrial analysis. A typical chemical sensor is a device that transforms chemical information in a selective and reversible way, ranging from the concentration of a specific sample component to total composition analysis, into an analytically useful signal. Much research work has been performed to achieve a chemical sensor with such excellent qualities as quick response, low cost, small size, superior sensitivity, good reversibility and selectivity, and excellent detection limit. This book introduces the latest advances on chemical sensors. It consists of 15 chapters composed by the researchers active in the field of chemical sensors, and is divided into 5 sections according to the classification following the principles of signal transducer. This collection of up-to-date information and the latest research progress on chemical sensor will provide valuable references and learning materials for all those working in the field of chemical sensors.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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  • 30
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Distillation is an important separation technique that has been used for many centuries to exploit the volatility differences between components in a mixture. The distillation process has many variations and applications. This book includes two sections on desalination and reactive distillation. It discusses desalination in the processes of solar and membrane distillation, with a focus on the reduction of energy costs to obtain potable water. It also discusses reactive distillation, which can be used in some cases to reduce the power duty in the separation process by using the reaction heat directly in the separation. The book includes cases of mathematical modeling, simulation, and optimization of the distillation process.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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  • 31
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Cyclodextrins (CDs) have attracted great interest from the research community as well as industries in an array of sectors because of their unique structural features. This book provides a comprehensive overview of CDs, beginning with their historical background. Chapters address such topics as the structure and physiochemical properties of CDs, advancements in the field, and potential applications of these materials in fields such as drug delivery and sensing. This book reveals new frontiers in the CD world and is a useful resource for organic, analytical, and supramolecular chemists as well as scientists engaged in biological and material sciences.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
    Language: English
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  • 32
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The book presents a comprehensive overview of sorption, which is a multi-parametric separation process. It is extensively used in the removal of various pollutants from the tertiary stage of wastewater treatment, from leachates, etc. It discusses fundamental points of the technique as well as kinetic theories and isotherms. It also examines the synthesis and characterizations of all studied adsorbent materials to find their paths of sorption. Finally, it highlights the importance of having a cost-estimation plan for the synthesis of sorbent materials as well as predictions for their reusability.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRX Surface chemistry and adsorption
    Language: English
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  • 33
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Carotenoids are natural and versatile secondary metabolites, most of them showing colours that vary from yellow to red. They are widespread among living beings where they are involved in many biological roles reporting beneficial actions. To date, more than 750 carotenoids have been described in nature. Humans cannot synthesize carotenoids de novo, thus they are mainly obtained through diet. In fact, carotenoids are consistently found in tissues or biological fluids where they play a beneficial decreasing the risk of developing some diseases.During the last half-century, significant advances in carotenoids research have been made. This book highlights new perspectives and applications of carotenoids including characterization and isolation of new compounds (including rare carotenoids), their production at a mid-large scale (involving new innovative approaches), and uses of carotenoids in different biotechnological fields like food science, biomedicine, and cosmetics.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 34
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Infrared Spectroscopy - Perspectives and Applications is a compendium of contributions from experts in the field of infrared (IR) spectroscopy. This assembly of investigations and reviews provides a comprehensive overview of the fundamentals as well as the groundbreaking applications in the field. Chapters discuss IR spectroscopy applications in the food and biomedicine sectors and for measuring transport through polymer membranes, characterizing lignocellulosic biomasses, detecting adulterants, and characterizing enamel surface advancements. This book is an invaluable resource and reference for students, researchers, and other interested readers.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry::PNFS Spectrum analysis, spectrochemistry, mass spectrometry
    Language: English
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  • 35
    Publication Date: 2023-03-08
    Description: © The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in LeClerc, H., Tompsett, G., Paulsen, A., McKenna, A., Niles, S., Reddy, C., Nelson, R., Cheng, F., Teixeira, A., & Timko, M. Hydroxyapatite catalyzed hydrothermal liquefaction transforms food waste from an environmental liability to renewable fuel. IScience, 25(9), (2022): 104916, https://doi.org/10.1016/j.isci.2022.104916.
    Description: Food waste is an abundant and inexpensive resource for the production of renewable fuels. Biocrude yields obtained from hydrothermal liquefaction (HTL) of food waste can be boosted using hydroxyapatite (HAP) as an inexpensive and abundant catalyst. Combining HAP with an inexpensive homogeneous base increased biocrude yield from 14 ± 1 to 37 ± 3%, resulting in the recovery of 49 ± 2% of the energy contained in the food waste feed. Detailed product analysis revealed the importance of fatty-acid oligomerization during biocrude formation, highlighting the role of acid-base catalysts in promoting condensation reactions. Economic and environmental analysis found that the new technology has the potential to reduce US greenhouse gas emissions by 2.6% while producing renewable diesel with a minimum fuel selling price of $1.06/GGE. HAP can play a role in transforming food waste from a liability to a renewable fuel.
    Description: This work was funded by the DOE Bioenergy Technology Office (DE-EE0008513), a DOE DBIR (DE-SC0015784) and the MassCEC. The authors thank WenWen Yao, Department of Environmental Science at WPI, for TOC analysis, Mainstream Engineering for heating value characterization of the oil and solid samples, Wei Fan for assistance in obtaining SEM images and, Julia Martin and Ronald Grimm for their assistance in collecting XPS data, and Jeffrey R. Page for his assistance with oil upgrading and analysis. HOL was partially funded for this work by NSF Graduate Research Fellowship award number 2038257. A portion of this work was performed at the National High Magnetic Field Laboratory Ion Cyclotron Resonance user facility, which is supported by the NSF Division of Materials Research and Division of Chemistry through DMR 16-44779 and the State of Florida.
    Keywords: Chemistry ; Chemical engineering ; Catalysis
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 36
    Publication Date: 2024-02-26
    Description: Identifcation of ontogenetic age classes plays an important role in the felds of zoology, palaeontology and archaeology, where accurate age classifcations of (sub)fossil remains are a crucial component for the reconstruction \nof past life. Textural ageing\xe2\x80\x94the identifcation of age-related bone surface textures\xe2\x80\x94provides a size-independent \nmethod for age assessment of vertebrate material. However, most of the work so far is limited to qualitative results. \nWhile qualitative approaches provide helpful insights on textural ageing patterns, they are heavily subject to observer \nbias and fall short of quantitative data relevant for detailed statistical analyses and cross-comparisons. Here, we present a pilot study on the application of 3D surface digital microscopy to quantify bone surface textures on the long \nbones of the grey heron (Ardea cinerea) and the Canada goose (Branta canadensis) using internationally verifed \nroughness parameters. Using a standardised measuring protocol, computed roughness values show a strong correlation with qualitative descriptions of textural patterns. Overall, higher roughness values correspond to increased numbers of grooves and pits and vice versa. Most of the roughness parameters allowed distinguishing between diferent \nontogenetic classes and closely followed the typical sigmoidal animal growth curve. Our results show that bone \ntexture quantifcation is a feasible approach to identifying ontogenetic age classes.
    Keywords: General Physics and Astronomy ; General Environmental Science ; General Biochemistry ; Genetics and Molecular Biology ; General Materials Science ; General Chemistry ; Roughness ; Surfaces ; Taphonomy ; Topography ; Bone ; Ontogeny ; Digital microscopy
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/article
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  • 37
    Publication Date: 2024-04-05
    Description: Chemiebezogene Kompetenzen werden bereits im Sachunterricht der Grundschule entwickelt und sollen im Chemieunterricht der Sekundarstufe I aufgegriffen und weiterentwickelt werden. Ziel dieser Studie war es, die chemiebezogenen Kompetenzen der Schülerinnen und Schüler in der Übergangsphase zwischen Sachunterricht und Chemieunterricht zu analysieren. In einer Ergänzungsstudie wurden zusätzlich sowohl die Auswirkungen der Schulschließungen aufgrund der SARS-CoV-II Pandemie auf die Kompetenzen der Schülerinnen und Schüler als auch der Einfluss einer veränderten Testadministration untersucht. Insgesamt wurden die Kompetenzen von 2262 Lernenden der Jahrgangsstufen 5 bis 9 zu drei Messzeitpunkten analysiert. Die Ergebnisse zeigen, dass die chemiebezogenen Kompetenzen sowohl zum Ende der Grundschulzeit als auch zu Beginn des Chemieunterrichts über alle Kompetenzbereiche hinweg sehr heterogen ausfallen. Dennoch sind sie zu Beginn des Chemieunterrichts in einigen Kompetenzbereichen höher ausgeprägt als zum Ende der Grundschulzeit. Nach den pandemiebedingten Schulschließungen waren die Kompetenzen ähnlich ausgeprägt wie in den gleichen Jahrgangsstufen vor den Schulschließungen. Eine während der Schulschließungen notwendige Bearbeitung der Testhefte von zu Hause aus führte vor allem bei den jüngeren Schülerinnen und Schülern zu besseren Testergebnissen als die Bearbeitung in der Schule. Um die Entwicklung chemiebezogener Kompetenzen in der Übergangsphase zu optimieren, sollte der Erwerb dieser Kompetenzen bereits im Sachunterricht einheitlicher gestaltet werden.
    Keywords: Science ; Chemistry ; Education ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: German
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  • 38
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    Logos Verlag Berlin | Logos Verlag Berlin
    Publication Date: 2024-04-05
    Description: In 2005, the hybrid model was published by Prof. H.-D. Alber and Prof. P. Zhu as an alternative to the Allen-Cahn model for the description of phase field transformations. With low interfacial energy, it is more efficient, since the resolution of the diffuse interface is numerically broader for the same solution accuracy and allows coarser meshing. The solutions of both models are associated with energy minimisation and in this work the error terms introduced in the earlier publications are discussed and documented using one and two dimensional numerical simulations. In the last part of this book, phase field problems, initially not coupled with material equations, are combined with linear elasticity and, after simple introductory examples, a growing martensitic inclusion is simulated and compared with literature data. In addition to the confirmed numerical advantage, another phenomenon not previously described in the literature is found: with the hybrid model, in contrast to the examples calculated with the Allen-Cahn model, an inclusion driven mainly by curvature energy does not disappear completely. The opposite problem prevents inclusions from growing from very small initial configurations, but this fact can be remedied by a very finely chosen diffuse interface width and by analysing and adjusting the terms that generate the modelling errors. The last example shows that the hybrid model can be used with numerical advantages despite the above mentioned peculiarities.
    Keywords: Science ; Chemistry ; Mathematics ; Science ; Physics ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PB Mathematics ; thema EDItEUR::P Mathematics and Science::PH Physics
    Language: English
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  • 39
    Publication Date: 2024-04-05
    Description: Das selbstgesteuerte Experimentieren ist laut den nationalen Bildungsstandards sowie den Lehrplänen im Fach Chemie ein wichtiger Bestandteil der naturwissenschaftlichen Schulbildung. Offene Experimentierformen sind jedoch wenig etabliert. Um das selbstgesteuerte Experimentieren in die Unterrichtspraxis zu implementieren, wurde im Rahmen dieses Forschungsprojekts eine eintägige Lehrkräftefortbildung zur Konzeption von selbstgesteuerten Experimenten im Chemieunterricht durchgeführt. Dazu wurde ein literaturbasiertes Strukturierungskonzept entwickelt, mit dem die Lehrkräfte kochbuchartige Schulversuche zu selbstgesteuerten und kompetenzorientierten Experimenten mit beliebigen Öffnungsgraden modifizieren können. Begleitend zur Fortbildung wurde im Prä-Post-Follow-Up-Design das fachdidaktische Wissen der Teilnehmenden hinsichtlich der Planung von selbstgesteuerten Experimenten empirisch überprüft. Zur Erfassung dieses Konstrukts wurde ein neues Messinstrument literaturbasiert entwickelt und die Güte des Messinstruments evaluiert. Die Auswertungen zeigen, dass die Fortbildung hinsichtlich des fachdidaktischen Wissens der Lehrkräfte kurz- sowie langfristig lernförderlich ist und die Fortbildung von den Teilnehmenden positiv bewertet wird. Die Reliabilitätsanalyse sowie die Validierungsstudie zeigen, dass der Test sowohl reliabel als auch valide ist. In Folgestudien könnte die langfristige Verhaltensänderung der Lehrkräfte bezüglich der Implementierung des selbstgesteuerten Experimentierens in den Unterricht untersucht werden.
    Keywords: Science ; Chemistry ; Science ; Education ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: German
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  • 40
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    Logos Verlag Berlin | Logos Verlag Berlin
    Publication Date: 2024-04-05
    Description: Konsumgüter werden beispielsweise mit Slogans wie "Gut in Bio. Schlecht in Chemie." beworben. Dabei wird intendiert, sich gezielt von "Chemie" abzugrenzen und sich das positive Bild von "Natur" zu Nutze zu machen. Dies prägt die öffentliche Meinung und trägt zu einer antagonistisch-wertenden Sicht von "Chemie" und "Natur" bei. Dass Chemie als Naturwissenschaft der Beschreibung der Natur dient, um deren Stoffe und Stoffumwandlungen zu erklären, ist dem Laien selten bewusst. Chemie findet überall statt, insbesondere in der Natur! Genau an diesem Punkt setzt das Unterrichtskonzept "Chemie Pur - Unterrichten in der Naturglqq an. Ziel ist es, im Freiland, mit direkt vor Ort gewonnenen Naturstoffen, Umweltprozesse experimentell zu erarbeiten. Die projektbegleitende Evaluationsstudie stellte sich der Forschungsfrage, wie sich das Unterrichtskonzept auf das Fach- und Sachinteresse, auf die Naturverbundenheit sowie auf die Einstellung zu Chemie und Natur von Schülerinnen und Schülern der Sekundarstufe II auswirkt. Die Auswertung der Fragebogenergebnisse mit latenten Veränderungsmodellen haben gezeigt, dass die Intervention im Freiland das inhaltsbezogene Sachinteresse steigert und die Einstellung zu Chemie und Natur positiv beeinflusst sowie ein erhöhten Fachwissenszuwachs ermöglicht. Die gewonnenen Erkenntnisse können die Grundlage für die Entwicklung und Evaluation von good-practice-Ansätzen naturwissenschaftlicher Lernsituationen bilden. Das Unterrichtskonzept Chemie Pur leistet zudem einen Beitrag im Bereich Outdoor Education, um den Antagonismus von Chemie und Natur zu verringern.
    Keywords: Science ; Chemistry ; Science ; Education ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: German
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  • 41
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    The MIT Press | The MIT Press
    Publication Date: 2024-03-27
    Description: The original 1818 text of Mary Shelley's classic novel, with annotations and essays highlighting its scientific, ethical, and cautionary aspects. Mary Shelley's Frankenstein has endured in the popular imagination for two hundred years. Begun as a ghost story by an intellectually and socially precocious eighteen-year-old author during a cold and rainy summer on the shores of Lake Geneva, the dramatic tale of Victor Frankenstein and his stitched-together creature can be read as the ultimate parable of scientific hubris. Victor, “the modern Prometheus,” tried to do what he perhaps should have left to Nature: create life. Although the novel is most often discussed in literary-historical terms—as a seminal example of romanticism or as a groundbreaking early work of science fiction—Mary Shelley was keenly aware of contemporary scientific developments and incorporated them into her story. In our era of synthetic biology, artificial intelligence, robotics, and climate engineering, this edition of Frankenstein will resonate forcefully for readers with a background or interest in science and engineering, and anyone intrigued by the fundamental questions of creativity and responsibility. This edition of Frankenstein pairs the original 1818 version of the manuscript—meticulously line-edited and amended by Charles E. Robinson, one of the world's preeminent authorities on the text—with annotations and essays by leading scholars exploring the social and ethical aspects of scientific creativity raised by this remarkable story. The result is a unique and accessible edition of one of the most thought-provoking and influential novels ever written. Essays by Elizabeth Bear, Cory Doctorow, Heather E. Douglas, Josephine Johnston, Kate MacCord, Jane Maienschein, Anne K. Mellor, Alfred Nordmann
    Keywords: science fiction ; gothic ; horror ; European ; British ; literature ; fiction ; cautionary tale ; STEM ; science ; bioethics ; classic ; bicentennial ; Josephine Johnston ; Cory Doctorow ; Jane Maienschein ; Kate MacCord ; Alfred Nordmann ; Elizabeth Bear ; Anne K. Mellor ; Heather E. Douglas ; Frankenstein ; Creature ; Monster ; Mary Shelley ; Makers ; women in science ; science and anti-science ; values in science ; responsible innovation ; Industrial Revolution ; Mary Wollstonecraft ; William Godwin ; Percy Bysshe Shelley ; Galvanism ; Mount Tambora ; Myths ; Two Cultures ; epistolary novel ; Victor Frankenstein ; Geneva ; Prometheus ; Arctic ; Lord Byron ; John Polidori ; ghost stories ; Revisions ; Electricity ; Lightning ; Vitalism ; Chemistry ; Extinction ; Magnetism ; Moral responsibility ; Legal responsibility ; Social responsibility ; Consequences ; Obligations ; Ethics ; Maker Culture ; DIY ; Technology Adjacent Possible ; Facebook ; Surveillance ; Aristotle ; Fetal development ; Epigenesis ; Embryo ; Person ; Technoscience ; Alchemy ; uncanny valley ; animation ; complexity ; Morality ; Monstrosity ; Christianity ; Otherness ; Gender ; Nature ; Domestic Affections ; Women ; Sexuality ; Technical Sweetness ; Los Alamos ; Trinity Test ; Scientific Responsibility ; Nuclear Weapons ; adjacent possible ; synthetic biology ; robotics ; thema EDItEUR::F Fiction and Related items::FB Fiction: general and literary::FBC Classic fiction: general and literary ; thema EDItEUR::F Fiction and Related items::FL Science fiction::FLC Classic science fiction
    Language: English
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  • 42
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    Logos Verlag Berlin | Logos Verlag Berlin
    Publication Date: 2024-04-05
    Description: When auralizing moving sound sources in Virtual Reality (VR) environments, the two main input parameters are the location and radiated signal of the source. An array measurement-based model is developed to characterize moving sound sources regarding the two parameters in this thesis. This model utilizes beamforming, i.e. delay and sum beamforming (DSB) and compressive beamforming (CB) to obtain the locations and signals of moving sound sources. A spiral and a pseudorandom microphone array are designed for DSB and CB, respectively, to yield good localization ability and meet the requirement of CB. The de-Dopplerization technique is incorporated in the time-domain DSB to address moving source problems. Time-domain transfer functions (TDTFs) are calculated in terms of the spatial locations within the steering window of the moving source. TDTFs then form the sensing matrix of CB, thus allowing CB to solve moving source problem. DSB and CB are further extended to localize moving sound sources, and the reconstructed signals from the beamforming outputs are investigated to obtain the source signals. Moreover, localization and signal reconstruction are evaluated through varying parameters in the beamforming procedures, i.e. steering position, steering window length and source speed for a moving periodic signal using DSB, and regularization parameter, signal to noise ratio (SNR), steering window length, source speed, array to source motion trajectory and mismatch for a moving engine signal using CB. The parameter studies show guidelines of parameter selection based on the given situations in this thesis for modeling moving source using beamforming. Both algorithms are able to reconstruct the moving signals in the given scenarios. Although CB outperforms DSB in terms of signal reconstruction under particular conditions, the localization abilities of the two algorithms are quite similar. The practicability of the model has been applied on pass-by measurements of a moving loudspeaker using the designed arrays, and the results can match the conclusions drawn above from simulations. Finally, a framework on how to apply the model for moving source auralization is proposed.
    Keywords: Science ; Chemistry ; Technology & Engineering ; Construction ; Technology & Engineering ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TN Civil engineering, surveying and building::TNK Building construction and materials ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
    Language: English
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  • 43
    Publication Date: 2024-04-05
    Description: Neuere Erkenntnisse zum Umsatzverhalten an Dieseloxidationskatalysatoren (DOCs) zeigen, dass das Umsatzverhalten von Schadstoffen vom Oxidationsgrad der verwendeten Edelmetallkatalysatoren abhängen kann. Dabei wird deutlich, dass sich der Oxidationsgrad bei typischen Abgaszusammensetzungen langsam und reversibel mit der Katalysatortemperatur ändert. Das kann bei periodischen Katalysatortemperaturänderungen zu einem ausgeprägten Hystereseverhalten führen. Bisherige Ergebnisse liegen insbesondere zum Verhalten der NO-Oxidation an Platin-Katalysatoren vor. Ziel der vorliegenden Arbeit ist es daher, die Untersuchungen auf seriennahe Pd- und PtPd-Mischkatalysatoren sowie auf andere abgastypische Schadstoffe, wie CO und Kohlenwasserstoffe, zu erweitern und dabei auch den Einfluss der Katalysatoralterung zu erfassen. Es wurde ein globalkinetisches Modell entwickelt und an die experimentellen Befunde angepasst. Dabei zeigte sich, dass es in der Regel möglich ist, das Umsatzverhalten bei reinen Pt- und Pd-Katalysatoren mit diesem örtlich eindimensionalen, makrokinetischen Zweiphasenmodell zutreffend zu beschreiben, wohingegen das Verhalten auf Pt/Pd-Mischkatalysatoren weniger gut simuliert werden kann. Dies ist vermutlich auf die heterogene Struktur der Pt/Pd-legierten Partikel zurückzuführen.
    Keywords: Science ; Chemistry ; Technology & Engineering ; Chemical & Biochemical ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering
    Language: German
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  • 44
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: The Frontiers in Chemistry Editorial Office team are delighted to present the inaugural “Frontiers in Chemistry: Rising Stars” article collection, showcasing the high-quality work of internationally recognized researchers in the early stages of their independent careers. All Rising Star researchers featured within this collection were individually nominated by the Journal’s Chief Editors in recognition of their potential to influence the future directions in their respective fields. The work presented here highlights the diversity of research performed across the entire breadth of the chemical sciences, and presents advances in theory, experiment and methodology with applications to compelling problems. This Editorial features the corresponding author(s) of each paper published within this important collection, ordered by section alphabetically, highlighting them as the great researchers of the future. The Frontiers in Chemistry Editorial Office team would like to thank each researcher who contributed their work to this collection. We would also like to personally thank our Chief Editors for their exemplary leadership of this article collection; their strong support and passion for this important, community-driven collection has ensured its success and global impact.
    Keywords: Green and Sustainable Chemistry ; Analytical Chemistry ; Theoretical and Computational Chemistry ; Polymer Chemistry ; Medicinal and Pharmaceutical Chemistry ; Organic Chemistry ; Nanoscience ; Catalysis and Photocatalysis ; Supramolecular Chemistry ; Electrochemistry ; Inorganic Chemistry ; Chemical Biology ; thema EDItEUR::P Mathematics and Science::PD Science: general issues
    Language: English
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  • 45
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    Taylor & Francis | CRC Press
    Publication Date: 2024-03-31
    Description: Hydroxyapatite coatings are of great importance in the biological and biomedical coatings fields, especially in the current era of nanotechnology and bioapplications. With a bonelike structure that promotes osseointegration, hydroxyapatite coating can be applied to otherwise bioinactive implants to make their surface bioactive, thus achieving faster healing and recovery. In addition to applications in orthopedic and dental implants, this coating can also be used in drug delivery. Hydroxyapatite Coatings for Biomedical Applications explores developments in the processing and property characterization and applications of hydroxyapatite to provide timely information for active researchers and newcomers alike. In eight carefully reviewed chapters, hydroxyapatite experts from the United States, Japan, Singapore, and China present the latest on topics ranging from deposition processes to biomedical applications in implants and drug delivery. This book discusses: Magnetron sputtering and electrochemical deposition The modification of hydroxyapatite properties by sol–gel deposition to incorporate other elements found in natural bones, such as zinc, magnesium, and fluorine The use of pure hydroxyapatite in drug delivery applications The growth or self-assembly of hydroxyapatite on shape memory alloy Hydroxyapatite composite coatings—with carbon nanotubes, titanium dioxide (TiO2), and others—on the titanium alloy Offering valuable insights and a wealth of data, including numerous tables and figures, this is a rich source of information for research on hydroxyapatite coatings. Each chapter also covers material that provides an accessible stepping stone for those who are new to the field.
    Keywords: Pre-clinical medicine: basic sciences ; Chemistry ; Materials science ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 46
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Nanofibers, particularly those of a carbonaceous content, have received increased interest in the past two decades due to their outstanding physico-chemical characteristics and their possibility to form and contribute towards a plethora of potentially advantageous materials for consumer, industrial and medical applications. Despite this, and together with the numerous research studies and published articles that have sought to investigate these aspects, the potential impact of CNTs is still not understood. Whether or not nanofibers may be able to provide a sophisticated alternative to conventional materials is still debatable, whilst their effects upon both environmental and human health are highly equivocal. How nanofibers are conceived can determine how they may interact with different environments, such as the human body. Understanding each key step of the synthesis and production of nanofibers to their use within potential applications is therefore essential in gaining an insight into how they may be perceived by any biological system and environment. Thus, obtaining such information will enable all scientific communities to begin to realize the potential advantages posed by nanofibers. The aim of this Special Issue therefore, was to provide a collective overview of nanofibers; ‘from synthesis to application’. The Issue particularly focuses upon carbon-based nanofibers, but also highlights alternative nanofiber types. Emphasis is given holistically, with articles discussing the production routes of nanofibers, their plight during their life-cycle (origin to applied form and effects over time), as well as how nanofibers could either incite conflict, or provide aid to human and environmental health.
    Keywords: QD1-999 ; Toxicology ; Chemistry ; Biology ; Material Science ; Nanofibers ; Nanotechnology ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 47
    Publication Date: 2024-04-04
    Description: This volume, occasioned by the centenary of the Fritz Haber Institute, formerly the Institute for Physical Chemistry and Electrochemistry, covers the institute's scientific and institutional history from its founding until the present. The institute was among the earliest established by the Kaiser Wilhelm Society, and its inauguration was one of the first steps in the development of Berlin-Dahlem into a center for scientific research. Its establishment was made possible by an endowment from Leopold Koppel, granted on the condition that Fritz Haber, well-known for his discovery of a method to synthesize ammonia from its elements, be made its director. The history of the institute has largely paralleled that of 20th-century Germany. It undertook controversial weapons research during World War I, followed by a "Golden Era" during the 1920s, in spite of financial hardships.
    Keywords: Chemistry ; Chemistry ; Fritz Haber Institute ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDX History of science
    Language: English
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  • 48
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-04-04
    Description: Die Chemie büßt zugunsten physikalischer und lebenswissenschaftlicher Konzeptionen zunehmend an Deutungsmacht über die molekulare Welt ein. Sandra Lang untersucht, inwiefern die Ausdifferenzierung der chemischen Wissenschaften mit sich ebenfalls ausdifferenzierenden Zugriffen auf das Molekulare zusammenhängt. Anhand der vier exemplarischen Grenzfelder Materialwissenschaften, Biomedizin, Pharmazie und Quantenchemie und deren Narrative zur molekularen Eigenschaft der Chiralität veranschaulicht sie die transformative Phase der Chemie angesichts sich wandelnder Innovationsdispositive.
    Keywords: Chemie ; Chiralität ; Molekülkonzept ; Naturwissenschaften ; Grenzarbeit ; Interdisziplinarität ; Hybridität ; Wissenschaft ; Technik ; Wissenschaftssoziologie ; Techniksoziologie ; Wissenssoziologie ; Wissenschaftsgeschichte ; Soziologie ; Chemistry ; Chirality ; Molecule Concept ; Natural Sciences ; Border Work ; Interdisciplinarity ; Hybridity ; Science ; Technology ; Sociology of Science ; Sociology of Technology ; Sociology of Knowledge ; History of Science ; Sociology ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology
    Language: German
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  • 49
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    De Gruyter | De Gruyter
    Publication Date: 2024-04-11
    Description: Presents technologies and key concepts to produce suitable smart materials and intelligent structures for sensing, information and communication technology, biomedical applications (drug delivery, hyperthermia therapy), self-healing, flexible memories and construction technologies. Novel developments of environmental friendly, cost-effective and scalable production processes are discussed by experts in the field.
    Keywords: Science ; Chemistry ; Industrial & Technical ; Technology & Engineering ; Textiles & Polymers ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 50
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    De Gruyter | De Gruyter
    Publication Date: 2024-04-05
    Description: Comprise definition of 1500 terms. Innovation from A to Z presents a glossary, including: Terms, older terms whose meanings have changed, acronyms, synonyms, famous names, selected abbreviations, and cross-references. A highly interdisciplinary approach incorporating strategy and entrepreneurship with technology and engineering sciences, economics, marketing, organizational behavior and theory. Ideal for engineers, managers, sales people and economists. Innovation Technology from A to Z Glossary of terms, including acronyms, synonyms, abbreviations, cross-references 1500 terms supplemented by figures and tables that clearly demonstrate the state-of-the-art in Innovation Technology
    Keywords: Science ; Chemistry ; Technology & Engineering ; Agriculture ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming
    Language: English
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  • 51
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    Coimbra University Press
    Publication Date: 2022-01-31
    Description: This work brings together various contributions from experts in very diverse areas of knowledge, to discuss the theme ‘Light’ from various points of view. The subjects gathered in this work come from the areas of Physics, Philosophy, Transcendence, Chemistry, Optics, Literature, History of Sciences, History, Geography, International Relations, Biology, Psychology, Art, Cinema and Photography, Medicine and Museology. The texts partially reflect the contents presented at the interdisciplinary colloquium ‘Visões da Luz’ held in October 2015, on the occasion of the International Year of Light 2015, under the aegis of III-UC and open to academia and society, to teachers of the Basic and Secondary Education.
    Keywords: Geography ; Chemistry ; Literature ; Geology ; Light ; Optics ; Biology ; History ; Physics
    Language: Portuguese
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  • 52
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-01-31
    Description: Today, sustainability of a healthy freshwater ecosystem and its associated ecosystem services are hot issues with ever-growing attention placed upon them. We are increasingly recognizing that they are crucial for the survival of the aquatic biota and human beings on our planet. The efficient monitoring of water resources is fundamental for effective management of water quality and aquatic ecosystems. The first stage in sustainable ecosystem management is the evaluation of the current status of target ecosystems. Traditionally, and even today, physico-chemical parameters have mainly been used to evaluate the quality of water resources. However, they have a large limit to grab the wholeness of water system, particularly in the sense of ecosystem health and integrity, for which ecological monitoring should be based on biological factors. Various approaches are applicable to ecosystem health assessment at different levels of the biological hierarchy, from genes to ecosystems. This Special Issue is designed to improve scientific understanding and strategies for sound aquatic ecosystem management and services for researchers, decision makers, and stakeholders.
    Keywords: Limnology ; Aquatic ecosystem assessment Aquatic ecosystem management ; Restoration ; Aquatic ecosystem services ; Aquatic ecology ; Aquatic ecosystem policy ; Conservation ; Ecohydrology ; Aquatic ecosystem monitoring ; Streams/ Rivers/ Lakes/ Wetlands ; Biological indicators
    Language: English
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  • 53
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2004-05-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malakoff, David -- New York, N.Y. -- Science. 2004 May 28;304(5675):1283.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15166364" target="_blank"〉PubMed〈/a〉
    Keywords: Biotechnology ; Career Choice ; Chemistry ; Emigration and Immigration ; History, 20th Century ; History, 21st Century ; Siberia ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 54
    Publication Date: 2011-08-24
    Description: Carbon nanotubes (CNTs) used as a probe for scanning probe microscopy has become one of the many potential usages of CNTs that is finding real applications in scientific research and industrial communities. It has been proposed that the unique mechanical buckling properties of the CNT would lessen the imaging force exerted on the sample and, thus, make CNT scanning probes ideal for imaging soft materials, including biological samples in liquid environments. The hydrophobic nature of the CNT graphitic sidewall is clearly chemically incompatible with the aqueous solution requirements in some biological imaging applications. In this paper, we present electron micrograph results demonstrating the instability of CNT scanning probes when submerged in aqueous solution. Moreover, we also introduce a novel approach to resolve this chemical incompatibility problem. By coating the CNT probe with ethylenediamine, thus rendering the CNT probe less hydrophobic, we demonstrate the liquid imaging capability of treated CNT probes. Experimental data for imaging in aqueous solutions are presented, which include an ultrathin Ir film and DNA molecules on a mica surface.
    Keywords: Life Sciences (General)
    Type: IEEE Trans Nanobioscience (ISSN 1536-1241); Volume 3; 1; 56-60
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  • 55
    Publication Date: 2011-08-24
    Description: Ethylene production by 10 or 20 m2 stands of wheat, soybean, lettuce, potato, and tomato was monitored throughout growth and development in an atmospherically closed plant chamber. Chamber ethylene levels varied among species and rose during periods of canopy expansion and rapid growth for all species. Following this, ethylene levels either declined during seed fill and maturation for wheat and soybean, or remained relatively constant for potato and tomato (during flowering and early fruit development). Lettuce plants were harvested during rapid growth and peak ethylene production. Chamber ethylene levels increased rapidly during tomato ripening, reaching concentrations about 10 times that measured during vegetative growth. The highest ethylene production rates during vegetative growth ranged from 1.6 to 2.5 nmol m-2 d-1 during rapid growth of lettuce and wheat stands, or about 0.3 to 0.5 nmol g-1 fresh weight per hour. Estimates of stand ethylene production during tomato ripening showed that rates reached 43 nmol m-2 d-1 in one study and 93 nmol m-2 d-1 in a second study with higher lighting, or about 50x that of the rate during vegetative growth of tomato. In a related test with potato, the photoperiod was extended from 12 to 24 hours (continuous light) at 58 days after planting (to increase tuber yield), but this change in the environment caused a sharp increase in ethylene production from the basal rate of 0.4 to 6.2 nmol m-2 d-1. Following this, the photoperiod was changed back to 12 h at 61 days and ethylene levels decreased. The results suggest three separate categories of ethylene production were observed with whole stands of plants: 1) production during rapid vegetative growth, 2) production during climacteric fruit ripening, and 3) production from environmental stress.
    Keywords: Life Sciences (General)
    Type: HortScience : a publication of the American Society for Horticultural Science (ISSN 0018-5345); Volume 39; 7; 1541-5
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  • 56
    Publication Date: 2011-08-24
    Description: The productivity of lettuce in a combination of high light, high temperature, and elevated CO2 has not been commonly studied because rapid growth usually causes a calcium deficiency in meristems called tipburn, which greatly reduces quality and marketability. We eliminated tipburn by blowing air directly onto the meristem, which allowed us to increase the photosynthetic photon flux (PPF) to 1000 micromoles m-2 s-1 (57.6 mol m-2 d-1); two to three times higher than normally used for lettuce. Eliminating tipburn doubled edible yield at the highest PPF level. In addition to high PPF, CO2 was elevated to 1200 micromoles m-2 mol-1, which increased the temperature optimum from 25 to 30 degrees C. The higher temperature increased leaf expansion rate, which improved radiation capture and more than doubled yield. Photosynthetic efficiency, measured as canopy quantum yield in a whole-plant gas exchange system, steadily increased up to the highest temperature of 32 degrees C in high CO2. The highest productivity was 19 g m-2 d-1 of dry biomass (380 g d-1 fresh mass) averaged over the 23 days the plants received light. Without the limitation of tipburn, the combination of high PPF, high temperature, and elevated CO2 resulted in a 4-fold increase in growth rate over productivity in conventional environments.
    Keywords: Life Sciences (General)
    Type: Journal of the American Society for Horticultural Science. American Society for Horticultural Science (ISSN 0003-1062); Volume 129; 3; 331-8
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  • 57
    Publication Date: 2011-08-24
    Description: Nanomaterials are part of an industrial revolution to develop lightweight but strong materials for a variety of purposes. Single-wall carbon nanotubes are an important member of this class of materials. They structurally resemble rolled-up graphite sheets, usually with one end capped; individually they are about 1 nm in diameter and several microns long, but they often pack tightly together to form rods or ropes of microscopic sizes. Carbon nanotubes possess unique electrical, mechanical, and thermal properties and have many potential applications in the electronics, computer, and aerospace industries. Unprocessed nanotubes are very light and could become airborne and potentially reach the lungs. Because the toxicity of nanotubes in the lung is not known, their pulmonary toxicity was investigated. The three products studied were made by different methods and contained different types and amounts of residual catalytic metals. Mice were intratracheally instilled with 0, 0.1, or 0.5 mg of carbon nanotubes, a carbon black negative control, or a quartz positive control and euthanized 7 d or 90 d after the single treatment for histopathological study of the lungs. All nanotube products induced dose-dependent epithelioid granulomas and, in some cases, interstitial inflammation in the animals of the 7-d groups. These lesions persisted and were more pronounced in the 90-d groups; the lungs of some animals also revealed peribronchial inflammation and necrosis that had extended into the alveolar septa. The lungs of mice treated with carbon black were normal, whereas those treated with high-dose quartz revealed mild to moderate inflammation. These results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.
    Keywords: Life Sciences (General)
    Type: Toxicological sciences : an official journal of the Society of Toxicology (ISSN 1096-6080); Volume 77; 1; 126-34
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  • 58
    Publication Date: 2011-08-24
    Description: Rapid microbial monitoring technologies are invaluable in assessing contamination of spacecraft and associated environments. Universal and widespread elements of microbial structure and chemistry are logical targets for assessing microbial burden. Several biomarkers such as ATP, LPS, and DNA (ribosomal or spore-specific), were targeted to quantify either total bioburden or specific types of microbial contamination. The findings of these assays were compared with conventional, culture-dependent methods. This review evaluates the applicability and efficacy of some of these methods in monitoring the microbial burden of spacecraft and associated environments. Samples were collected from the surfaces of spacecraft, from surfaces of assembly facilities, and from drinking water reservoirs aboard the International Space Station (ISS). Culture-dependent techniques found species of Bacillus to be dominant on these surfaces. In contrast, rapid, culture-independent techniques revealed the presence of many Gram-positive and Gram-negative microorganisms, as well as actinomycetes and fungi. These included both cultivable and noncultivable microbes, findings further confirmed by DNA-based microbial detection techniques. Although the ISS drinking water was devoid of cultivable microbes, molecular-based techniques retrieved DNA sequences of numerous opportunistic pathogens. Each of the methods tested in this study has its advantages, and by coupling two or more of these techniques even more reliable information as to microbial burden is rapidly obtained. Copyright 2004 Springer-Verlag.
    Keywords: Life Sciences (General)
    Type: Microbial ecology (ISSN 0095-3628); Volume 47; 2; 150-8
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  • 59
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: The study of Earth's radiation belts is one of the oldest subjects in space physics. Despite the tremendous progress made in the last four decades, we still lack a complete understanding of the radiation belts in terms of their configurations, dynamics, and detailed physical accounts of their sources and sinks. The static nature of early empirical trapped radiation models, for examples, the NASA AP-8 and AE-8 models, renders those models inappropriate for predicting short-term radiation belt behaviors associated with geomagnetic storms and substorms. Due to incomplete data coverage, these models are also inaccurate at low altitudes (e.g., 〈1000 km) where many robotic and human space flights occur. The availability of radiation data from modern space missions and advancement in physical modeling and data management techniques have now allowed the development of new empirical and physical radiation belt models. In this paper, we will review the status of modern radiation belt modeling. Published by Elsevier Ltd on behalf of COSPAR.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 34; 6; 1441-50
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  • 60
    Publication Date: 2011-08-24
    Description: The latest process for producing large quantities of single-walled carbon nanotubes (SWNTs) to emerge from the Rice University, dubbed HiPco, is living up to its promise. The current production rates approach 450 mg/h (or 10 g/day), and nanotubes typically have no more than 7 mol % of iron impurities. Second-generation HiPco apparatus can run continuously for 7-10 days at a time. In the HiPco process nanotubes grow in high-pressure, high-temperature flowing CO on catalytic clusters of iron. Catalyst is formed in situ by thermal decomposition of iron pentacarbonyl, which is delivered intact within a cold CO flow and then rapidly mixed with hot CO in the reaction zone. Upon heating, the Fe(CO)5 decomposes into atoms that condense into larger clusters. SWNTs nucleate and grow on these particles in the gas phase via CO disproportionation: CO + CO --〉 CO2 + C (SWNT), catalyzed by the Fe surface. The concentration of CO2 produced in this reaction is equal to that of carbon and can therefore serve as a useful real-time feedback parameter. It was used to study and optimize SWNT production as a function of temperature, pressure, and Fe(CO)5 concentration. The results of the parametric study are in agreement with current understanding of the nanotube formation mechanism.
    Keywords: Life Sciences (General)
    Type: Journal of nanoscience and nanotechnology (ISSN 1533-4880); Volume 4; 4; 307-16
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  • 61
    Publication Date: 2011-08-24
    Description: Chemical kinetic models for the nucleation and growth of clusters and single-walled carbon nanotube (SWNT) growth are developed for numerical simulations of the production of SWNTs. Two models that involve evaporation and condensation of carbon and metal catalysts, a full model involving all carbon clusters up to C80, and a reduced model are discussed. The full model is based on a fullerene model, but nickel and carbon/nickel cluster reactions are added to form SWNTs from soot and fullerenes. The full model has a large number of species--so large that to incorporate them into a flow field computation for simulating laser ablation and arc processes requires that they be simplified. The model is reduced by defining large clusters that represent many various sized clusters. Comparisons are given between these models for cases that may be applicable to arc and laser ablation production. Solutions to the system of chemical rate equations of these models for a ramped temperature profile show that production of various species, including SWNTs, agree to within about 50% for a fast ramp, and within 10% for a slower temperature decay time.
    Keywords: Life Sciences (General)
    Type: Journal of nanoscience and nanotechnology (ISSN 1533-4880); Volume 4; 4; 368-76
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  • 62
    Publication Date: 2011-08-24
    Description: The cWINNOWER algorithm detects fuzzy motifs in DNA sequences rich in protein-binding signals. A signal is defined as any short nucleotide pattern having up to d mutations differing from a motif of length l. The algorithm finds such motifs if a clique consisting of a sufficiently large number of mutated copies of the motif (i.e., the signals) is present in the DNA sequence. The cWINNOWER algorithm substantially improves the sensitivity of the winnower method of Pevzner and Sze by imposing a consensus constraint, enabling it to detect much weaker signals. We studied the minimum detectable clique size qc as a function of sequence length N for random sequences. We found that qc increases linearly with N for a fast version of the algorithm based on counting three-member sub-cliques. Imposing consensus constraints reduces qc by a factor of three in this case, which makes the algorithm dramatically more sensitive. Our most sensitive algorithm, which counts four-member sub-cliques, needs a minimum of only 13 signals to detect motifs in a sequence of length N = 12,000 for (l, d) = (15, 4). Copyright Imperial College Press.
    Keywords: Life Sciences (General)
    Type: J Bioinform Comput Biol (ISSN 0219-7200); Volume 2; 1; 47-60
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  • 63
    Publication Date: 2011-08-24
    Description: Different types of lasers are now routinely used to prepare single-walled carbon nanotubes. The original method developed by researchers at Rice University used a "double-pulse laser oven" process. Several researchers have used variations of the lasers to include one-laser pulse (green or infrared), different pulse widths (ns to micros as well as continuous wave), and different laser wavelengths (e.g., CO2, or free electron lasers in the near to far infrared). Some of these variations are tried with different combinations and concentrations of metal catalysts, buffer gases (e.g., helium), oven temperatures, flow conditions, and even different porosities of the graphite targets. This article is an attempt to cover all these variations and their relative merits. Possible growth mechanisms under these different conditions will also be discussed.
    Keywords: Life Sciences (General)
    Type: Journal of nanoscience and nanotechnology (ISSN 1533-4880); Volume 4; 4; 317-25
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  • 64
    Publication Date: 2011-08-24
    Description: BACKGROUND: Reducing cost and time is the major concern in clinical diagnostics, particularly in molecular diagnostics. Miniaturization technologies have been recognized as promising solutions to provide low-cost microchips for diagnostics. With the recent advancement in nanotechnologies, it is possible to further improve detection sensitivity and simplify sample preparation by incorporating nanoscale elements in diagnostics devices. A fusion of micro- and nanotechnologies with biology has great potential for the development of low-cost disposable chips for rapid molecular analysis that can be carried out with simple handheld devices. APPROACH: Vertically aligned multiwalled carbon nanotubes (MWNTs) are fabricated on predeposited microelectrode pads and encapsulated in SiO2 dielectrics with only the very end exposed at the surface to form an inlaid nanoelectrode array (NEA). The NEA is used to collect the electrochemical signal associated with the target molecules binding to the probe molecules, which are covalently attached to the end of the MWNTs. CONTENT: A 3 x 3 microelectrode array is presented to demonstrate the miniaturization and multiplexing capability. A randomly distributed MWNT NEA is fabricated on each microelectrode pad. Selective functionalization of the MWNT end with a specific oligonucleotide probe and passivation of the SiO2 surface with ethylene glycol moieties are discussed. Ru(bpy)2+ -mediator-amplified guanine oxidation is used to directly measure the electrochemical signal associated with target molecules. SUMMARY: The discussed MWNT NEAs have ultrahigh sensitivity in direct electrochemical detection of guanine bases in the nucleic acid target. Fewer than approximately 1000 target nucleic acid molecules can be measured with a single microelectrode pad of approximately 20 x 20 microm2, which approaches the detection limit of laser scanners in fluorescence-based DNA microarray techniques. MWNT NEAs can be easily integrated with microelectronic circuitry and microfluidics for development of a fully automated system for rapid molecular analysis with minimum cost.
    Keywords: Life Sciences (General)
    Type: Clinical chemistry (ISSN 0009-9147); Volume 50; 10; 1886-93
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  • 65
    Publication Date: 2011-08-24
    Description: A detailed study was made of the biological cleaning effectiveness, defined in terms of the ability to remove bacterial spores, of a number of methods used to clean hardware surfaces. Aluminum (Al 6061) and titanium (Ti 6Al-4V) were chosen for the study as they were deemed the two materials most likely to be used in spacecraft extraterrestrial sampler construction. Metal coupons (1 cm x 2.5 cm) were precleaned and inoculated with 5.8 x 10(3) cultivable Bacillus subtilis spores, which are commonly found on spacecraft surfaces and in the assembly environments. The inoculated coupons were subsequently cleaned using: (1) 70% isopropyl alcohol wipe; (2) water wipe; (3) multiple-solvent flight-hardware cleaning procedures used at the Jet Propulsion Laboratory (JPL); (4) Johnson Space Center-developed ultrapure water rinse; and (5) a commercial, semi-aqueous, multiple-solvent (SAMS) cleaning process. The biological cleaning effectiveness was measured by agar plate assay, sterility test (growing in liquid media), and epifluorescent microscopy. None of the cleaning protocols tested completely removed viable spores from the surface of the aluminum. In contrast, titanium was capable of being cleaned to sterility by two methods, the JPL standard and the commercial SAMS cleaning process. Further investigation showed that the passivation step employed in the JPL standard method is an effective surface sterilant on both metals but not compatible with aluminum. It is recommended that titanium (Ti 6Al-4V) be considered superior to aluminum (Al 6061) for use in spacecraft sampling hardware, both for its potential to be cleaned to sterilization and for its ability to withstand the most effective cleaning protocols.
    Keywords: Life Sciences (General)
    Type: Astrobiology (ISSN 1531-1074); Volume 4; 3; 377-90
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  • 66
    Publication Date: 2011-08-24
    Description: Zoological data and a growing mythology contributed to ancient Western knowledge about large serpents. Yet little modern attention has been paid to the sources, transmission, and receipt in the early Middle Ages of the ancients' information concerning "dragons" and "sea serpents." Real animals--primarily pythons and whales--lie behind the ancient stories. Other animals, conflations of different animals, simple misunderstandings, and willful exaggerations are found to account for the fanciful embellishments, but primitive myths played no significant role in this process during classical times. The expedition of Alexander the Great into India (327-325 B.C.) and the Bagradas River incident in North Africa (256 B.C.) had enormous repercussions on the development of serpent lore. Credible evidence is found for the presence of ancient populations of pythons living along the North African coast west of Egypt and along the coast of the Arabian Sea between the Indus River and the Strait of Hormuz--places where they no longer exist today. The maximum sizes of ancient pythons may have been greater than those of today's specimens.
    Keywords: Life Sciences (General)
    Type: Isis; an international review devoted to the history of science and its cultural influences (ISSN 0021-1753); Volume 95; 2; 220-38
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  • 67
    Publication Date: 2011-08-24
    Description: The use of magnetic fluids and magnetic particles in combinatorial hyperthermia therapy for cancer treatment is reviewed. The investigation approach adopted for producing thermoregulating particles and tissue model studies for studying particle retention and heating characteristics is discussed.
    Keywords: Life Sciences (General)
    Type: Annals of the New York Academy of Sciences (ISSN 0077-8923); Volume 1027; 99-109
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  • 68
    Publication Date: 2011-08-24
    Description: Robert Barany won the 1914 Nobel Prize in medicine for his convection hypothesis for caloric stimulation. Microgravity caloric tests aboard the 1983 SpaceLab 1 mission produced nystagmus results that contradicted the basic premise of Barany's convection theory. In this paper, we present a fluid structural analysis of the caloric stimulation of the lateral semicircular canal. Direct numerical simulations indicate that on earth, natural convection is the dominant mechanism for endolymphatic flow. However, in the microgravity environment of orbiting spacecraft, where buoyancy effects are mitigated, an expansive convection becomes the sole mechanism for producing endolymph motion and cupular displacement. Transient 1 g and microgravity case studies are presented to delineate the different dynamic behaviors of the 1 g and microgravity endolymphatic flows. The associated fluid-structural interactions are also analyzed based on the time evolution of cupular displacements.
    Keywords: Life Sciences (General)
    Type: Annals of the New York Academy of Sciences (ISSN 0077-8923); Volume 1027; 360-70
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  • 69
    Publication Date: 2011-08-24
    Description: Plants will be an important component of future long-term space missions. Lighting systems for growing plants will need to be lightweight, reliable, and durable, and light-emitting diodes (LEDs) have these characteristics. Previous studies demonstrated that the combination of red and blue light was an effective light source for several crops. Yet the appearance of plants under red and blue lighting is purplish gray making visual assessment of any problems difficult. The addition of green light would make the plant leave appear green and normal similar to a natural setting under white light and may also offer a psychological benefit to the crew. Green supplemental lighting could also offer benefits, since green light can better penetrate the plant canopy and potentially increase plant growth by increasing photosynthesis from the leaves in the lower canopy. In this study, four light sources were tested: 1) red and blue LEDs (RB), 2) red and blue LEDs with green fluorescent lamps (RGB), 3) green fluorescent lamps (GF), and 4) cool-white fluorescent lamps (CWF), that provided 0%, 24%, 86%, and 51% of the total PPF in the green region of the spectrum, respectively. The addition of 24% green light (500 to 600 nm) to red and blue LEDs (RGB treatment) enhanced plant growth. The RGB treatment plants produced more biomass than the plants grown under the cool-white fluorescent lamps (CWF treatment), a commonly tested light source used as a broad-spectrum control.
    Keywords: Life Sciences (General)
    Type: HortScience : a publication of the American Society for Horticultural Science (ISSN 0018-5345); Volume 39; 7; 1617-22
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  • 70
    Publication Date: 2011-08-24
    Description: ALTEA-MICE will supplement the ALTEA project on astronauts and provide information on the functional visual impairment possibly induced by heavy ions during prolonged operations in microgravity. Goals of ALTEA-MICE are: (1) to investigate the effects of heavy ions on the visual system of normal and mutant mice with retinal defects; (2) to define reliable experimental conditions for space research; and (3) to develop animal models to study the physiological consequences of space travels on humans. Remotely controlled mouse setup, applied electrophysiological recording methods, remote particle monitoring, and experimental procedures were developed and tested. The project has proved feasible under laboratory-controlled conditions comparable in important aspects to those of astronauts' exposure to particle in space. Experiments are performed at the Brookhaven National Laboratories [BNL] (Upton, NY, USA) and the Gesellschaft fur Schwerionenforschung mbH [GSI]/Biophysik (Darmstadt, FRG) to identify possible electrophysiological changes and/or activation of protective mechanisms in response to pulsed radiation. Offline data analyses are in progress and observations are still anecdotal. Electrophysiological changes after pulsed radiation are within the limits of spontaneous variability under anesthesia, with only indirect evidence of possible retinal/cortical responses. Immunostaining showed changes (e.g. increased expression of FGF2 protein in the outer nuclear layer) suggesting a retinal stress reaction to high-energy particles of potential relevance in space. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 33; 8; 1347-51
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  • 71
    Publication Date: 2011-08-24
    Description: The ALTEA project investigates the risks of functional brain damage induced by particle radiation in space. A modular facility (the ALTEA facility) is being implemented and will be operated in the International Space Station (ISS) to record electrophysiological and behavioral descriptors of brain function and to monitor their time dynamics and correlation with particles and space environment. The focus of the program will be on abnormal visual perceptions (often reported as "light flashes" by astronauts) and the impact on retinal and brain visual structures of particle in microgravity conditions. The facility will be made available to the international scientific community for human neurophysiological, electrophysiological and psychophysics experiments, studies on particle fluxes, and dosimetry. A precursor of ALTEA (the 'Alteino' project) helps set the experimental baseline for the ALTEA experiments, while providing novel information on the radiation environment onboard the ISS and on the brain electrophysiology of the astronauts during orbital flights. Alteino was flown to the ISS on the Soyuz TM34 as part of mission Marco Polo. Controlled ground experiments using mice and accelerator beams complete the experimental strategy of ALTEA. We present here the status of progress of the ALTEA project and preliminary results of the Alteino study on brain dynamics, particle fluxes and abnormal visual perceptions. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 33; 8; 1352-7
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  • 72
    Publication Date: 2011-08-24
    Description: The main goal of PUR experiment (phage and uracil response) is to examine and quantify the effect of specific space conditions on nucleic acid models. To achieve this an improved method was elaborated for the preparation of DNA and bacteriophage thin films. The homogeneity of the films was controlled by UV spectroscopy and microscopy. To provide experimental evidence for the hypothesis that interplanetary transfer of the genetic material is possible, phage T7 and isolated T7 DNA thin films have been exposed to selected space conditions: intense UVC radiation (lambda=254 nm) and high vacuum (10(-4) Pa). The effects of DNA hydration, conformation and packing on UV radiation damage were examined. Characteristic changes in the absorption spectrum, in the electrophoretic pattern of DNA and the decrease of the amount of PCR products have been detected indicating the photodamage of isolated and intraphage DNA. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 33; 8; 1306-10
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  • 73
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: The Journal of eukaryotic microbiology (ISSN 1066-5234); Volume 51; 1; 3-7
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  • 74
    Publication Date: 2011-08-24
    Description: Anionic (sodium laureth sulfate, SLES), amphoteric (cocamidopropyl betaine, CAPB) and nonionic (alcohol polyethoxylate, AE) surfactants were added to separate nutrient film technique (NFT) hydroponic systems containing dwarf wheat (Triticum aestivum cv. USU Apogee) in a series of 21 day trials. Surfactant was added either in a (1). temporally dynamic mode (1-3 g surfactant m(-2) growing area d(-1)) as effected by automatic addition of a 300 ppm surfactant solution to meet plant water demand, or (2). continuous mode (2 g surfactant m(-2) growing area d(-1)) as effected by slow addition (10 mLh(-1)) of a 2000 ppm surfactant solution beginning at 4d after planting. SLES showed rapid primary degradation in both experiments, with no accumulation 24 h after initial addition. CAPB and AE were degraded less rapidly, with 30-50% remaining 24 h after initial addition, but CAPB and AE levels were below detection limit for the remainder of the study. No reductions in vegetative growth of wheat were observed in response to SLES, but biomass was reduced 20-25% with CAPB and AE. Microbial communities associated with both the plant roots and wetted hardware surfaces actively degraded the surfactants, as determined by monitoring surfactant levels following pulse additions at day 20 (with plants) and day 21 (after plant removal). In order to test whether the biofilm communities could ameliorate phytotoxicity by providing a microbial community acclimated for CAPB and AE decay, the continuous exposure systems were planted with wheat seeds after crop removal at day 21. Acclimation resulted in faster primary degradation (〉90% within 24h) and reduced phytotoxicity. Overall, the studies indicate that relatively small areas (3-5m(2)) of hydroponic plant systems can process per capita production of mixed surfactants (5-10 g x person(-1)d(-1)) with minimal effects on plant growth.
    Keywords: Life Sciences (General)
    Type: Water research (ISSN 0043-1354); Volume 38; 8; 1952-62
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  • 75
    Publication Date: 2011-08-24
    Description: Mutations in BRCA1 are characterized by predisposition to breast cancer, ovarian cancer and prostate cancer as well as colon cancer. Prognosis for this cancer survival depends upon the stage at which cancer is diagnosed. Reliable and rapid mutation detection is crucial for the early diagnosis and treatment. We developed an electronic assay for the detection of a representative single nucleotide polymorphism (SNP), deletion and insertion in BRCA1 gene by the microelectronics microarray instrumentation. The assay is rapid, and it takes 30 minutes for the immobilization of target DNA samples, hybridization, washing and readout. The assay is multiplexing since it is carried out at the same temperature and buffer conditions for each step. The assay is also highly specific, as the signal-to-noise ratio is much larger than recommended value (72.86 to 321.05 vs. 5) for homozygotes genotyping, and signal ratio close to the perfect value 1 for heterozygotes genotyping (1.04).
    Keywords: Life Sciences (General)
    Type: Biomed Microdevices (ISSN 1387-2176); Volume 6; 1; 55-60
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  • 76
    Publication Date: 2011-08-24
    Description: According to D. E. Broadbent's (1958) selective filter theory, people do not process unattended stimuli beyond the analysis of basic physical properties. This theory was later rejected on the basis of numerous findings that people identify irrelevant (and supposedly unattended) stimuli. A careful review of this evidence, however, reveals strong reasons to doubt that these irrelevant stimuli were in fact unattended. This review exposed a clear need for new experiments with tight control over the locus of attention. The authors present 5 such experiments using a priming paradigm. When steps were taken to ensure that irrelevant stimuli were not attended, these stimuli produced no priming effects. Hence, the authors found no evidence that unattended stimuli can be identified. The results support a modern version of Broadbent's selective theory, updated to reflect recent research advances. 2004 APA.
    Keywords: Life Sciences (General)
    Type: Psychological review (ISSN 0033-295X); Volume 111; 4; 880-913
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  • 77
    Publication Date: 2011-08-24
    Description: We use spatially continuous satellite data as a correlate of precipitation within tropical Africa and show that the majority of documented Ebola hemorrhagic fever outbreaks were closely associated with sharply drier conditions at the end of the rainy season. We propose that these trigger events may enhance transmission of Ebola virus from its cryptic reservoir to humans. These findings suggest specific directions to help understand the sylvatic cycle of the virus and may provide early warning tools to detect possible future outbreaks of this enigmatic disease.
    Keywords: Life Sciences (General)
    Type: The American journal of tropical medicine and hygiene (ISSN 0002-9637); Volume 71; 5; 664-74
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  • 78
    Publication Date: 2011-08-24
    Description: In this paper we analyze the effects of the following phenomena associated with the thermocapillary migration of a drop. The first is the influence of Newtonian surface rheology of the interface and the second is that of the energy changes associated with stretching and shrinkage of the interfacial area elements, when the drop is in motion. The former occurs because of dissipative processes in the interfacial region, such as when surfactant molecules are adsorbed at the interface in sufficient concentration. The interface is typically modeled in this instance by ascribing to it a surface viscosity. This is a different effect from that of interfacial tension gradients arising from surfactant concentration gradients. The stretching and shrinkage of interfacial area elements leads to changes in the internal energy of these elements that affects the transport of energy in the fluids adjoining the interface. When an element on the interface is stretched, its internal energy increases because of the increase in its area. This energy is supplied by the neighboring fluids that are cooled as a consequence. Conversely, when an element on the interface shrinks, the adjoining fluids are warmed. In the case of a moving drop, elements of interfacial area are stretched in the forward half of the drop, and are shrunk in the rear half. Consequently, the temperature variation on the surface of the drop and its migration speed are modified. The analysis of the motion of a drop including these effects was first performed by LeVan in 1981, in the limit when convective transport of momentum and energy are negligible. We extend the analysis of LeVan to include the convective transport of momentum by demonstrating that an exact solution of the momentum equation is obtained for an arbitrary value of the Reynolds number. This solution is then used to calculate the slightly deformed shape of the drop from a sphere.
    Keywords: Life Sciences (General)
    Type: Annals of the New York Academy of Sciences (ISSN 0077-8923); Volume 1027; 303-10
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  • 79
    Publication Date: 2011-08-24
    Description: In order to determine the effect of the number of sonic boom occurrences on annoyance, a computer-based system was developed for studying the subjective response of people to the occurrence of simulated sonic booms in their homes. The system provided a degree of control over the noise exposure not found in community surveys and a degree of situational realism not available in the laboratory. A system was deployed for eight weeks in each of 33 homes. Each day from 4 to 63 sonic booms were played as the test subject went about his or her normal activities. At the end of the day, the test subjects rated their annoyance to the sonic booms heard during the day. The sonic booms consisted of different combinations of waveforms, levels, and occurrence rates. The experiment confirmed that the increase in annoyance resulting from multiple occurrences can be modeled by the addition of the term "10 * log(number of occurrences)" to the sonic boom level. Of several noise metrics considered, perceived level was the best annoyance predictor. Comparisons of the subjective responses to the different sonic boom waveforms found no differences that were not accounted for by the noise metrics.
    Keywords: Life Sciences (General)
    Type: The Journal of the Acoustical Society of America (ISSN 0001-4966); Volume 116; 3; 1573-84
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  • 80
    Publication Date: 2011-08-24
    Description: The noninvasive techniques of static and dynamic light scattering are emerging as valuable diagnostic tools for the early detection of ocular and systemic diseases. These include corneal abnormalities, pigmentary dispersion syndrome, glaucoma, cataract, diabetic vitreopathy, and possibly macular degeneration. Systemic conditions such as diabetes and possibly Alzheimer's disease can potentially be detected early via ocular tissues. The current state of development of these techniques for application to ophthalmic research and ultimately clinical practice is reviewed. (c) 2004 Society of Photo-Optical Instrumentation Engineers.
    Keywords: Life Sciences (General)
    Type: Journal of biomedical optics (ISSN 1083-3668); Volume 9; 1; 22-37
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  • 81
    Publication Date: 2011-08-24
    Description: A new optical scheme to detect glucose concentration in the aqueous humor of the eye is presented. The ultimate aim is to apply this technique in designing a new instrument for, routinely and frequently, noninvasively monitoring blood glucose levels in diabetic patients without contact (no index matching) between the eye and the instrument. The optical scheme exploits the Brewster reflection of circularly polarized light off of the lens of the eye. Theoretically, this reflected linearly polarized light on its way to the detector is expected to rotate its state of polarization, owing to the presence of glucose molecules in the aqueous humor of a patient's eye. An experimental laboratory setup based on this scheme was designed and tested by measuring a range of known concentrations of glucose solutions dissolved in water. (c) 2004 Society of Photo-Optical Instrumentation Engineers.
    Keywords: Life Sciences (General)
    Type: Journal of biomedical optics (ISSN 1083-3668); Volume 9; 1; 103-15
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  • 82
    Publication Date: 2011-08-24
    Description: A round-spore-forming Bacillus species that produces an exosporium was isolated from the surface of the Mars Odyssey spacecraft. This novel species has been characterized on the basis of phenotypic traits, 16S rDNA sequence analysis and DNA-DNA hybridization. According to the results of these analyses, this strain belongs to the genus Bacillus and is a Gram-positive, aerobic, rod-shaped, endospore-forming eubacterium. Ultrathin sections of the spores showed the presence of an exosporium, spore coat, cortex and core. 16S rDNA sequence similarities between this strain, Bacillus fusiformis and Bacillus silvestris were approximately 96% and DNA-DNA reassociation values with these two bacilli were 23 and 17%, respectively. Spores of the novel species were resistant to desiccation, H2O2 and UV and gamma radiation. Of all strains tested, the spores of this strain were the most consistently resistant and survived all of the challenges posed, i.e. exposure to conditions of desiccation (100% survival), H2O2 (26% survival), UV radiation (10% survival at 660 J m(-2)) and gamma radiation (0.4% survival). The name proposed for this novel bacterium is Bacillus odysseyi sp. nov.; the type strain is 34hs-1T (=ATCC PTA-4993T=NRRL B-30641T=NBRC 100172T).
    Keywords: Life Sciences (General)
    Type: International journal of systematic and evolutionary microbiology (ISSN 1466-5026); Volume 54; Pt 1; 195-201
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  • 83
    Publication Date: 2011-08-24
    Description: Orbital debris impacts on the International Space Station occur frequently. To date, none of the impacting particles has been large enough to penetrate manned pressurized volumes. We used the Manned Spacecraft Crew Survivability code to evaluate the risk to crew of penetrations of pressurized modules at two assembly stages: after Flight 1J, when the pressurized elements of Kibo, the Japanese Experiment Module, are present, and after Flight 1E, when the European Columbus Module is present. Our code is a Monte-Carlo simulation of impacts on the Station that considers several potential event types that could lead to crew loss. Among the statistics tabulated by the program is the probability of death of one or more crew members in the event of a penetration, expressed as the risk factor, R. This risk factor is dependent on details of crew operations during both ordinary circumstances and decompression emergencies, as well as on details of internal module configurations. We conducted trade studies considering these procedure and configuration details to determine the bounds on R at the 1J and 1E stages in the assembly sequence. Here we compare the R-factor bounds, and procedures could that reduce R at these stages. Published by Elsevier Ltd on behalf of COSPAR.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 34; 5; 1104-8
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  • 84
    Publication Date: 2011-08-24
    Description: Obtaining uniform mechano-dwarfing of Arabidopsis thaliana (L.) Heynh. seedlings within dense plantings is problematic. Alternative forms of mechano-stimulation were applied to seedlings in effort to obtain uniform growth reduction compared with undisturbed controls in both greenhouse and controlled growth environments. Arabidopsis grown under low photosynthetic photon flux (PPF) artificial light grew upright with limited leaf expansion, which enhanced mechano-responsiveness compared to that of rosette-growing plants under filtered sunlight or high PPF artificial light. Hypocotyls of seedlings grown at PPFs 〉 60 micromoles m-2 s-1 elongated less and had 6% less sensitivity to mechanical stress than seedlings grown at PPFs 〈 60 micromoles m-2 s-1. Fluorescent lamps alone (F) or fluorescent plus incandescent (F+I) lamps were compared for seedling responses to mechanical stress. Under F lighting, hypocotyl elongation was reduced 25% to 40% by twice-daily brush or plate treatments, and brushed seedlings exhibited more growth reduction than did plate treatments. Seedlings grown under F+I lamps exhibited similar stress-induced growth reduction compared to seedlings grown under F only, but stressed F+I seedlings lodged to a greater extent due to excessive hypocotyl elongation. Temperature-response studies using standardized F-only lighting indicated increased hypocotyl elongation but decreased leaf expansion, and decreased mechano-responsivity to brushing over the temperature range from 20 to 28 degrees C. Daylength studies indicated similar degrees of mechano-inhibition of hypocotyl elongation over the daylength range of 12, 16, 20, and 24 hours, whereas fresh weight of stressed seedling shoots declined compared to controls. A combination of environmental growth parameters that give repeatable, visual mechanical dwarfing of Arabidopsis include low-PPF fluorescent lighting from 55 to 60 micromoles m-2 s-1, ambient temperatures from 22 to 25 degrees C, and twice-daily brush treatments.
    Keywords: Life Sciences (General)
    Type: Journal of the American Society for Horticultural Science. American Society for Horticultural Science (ISSN 0003-1062); Volume 129; 3; 339-43
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  • 85
    Publication Date: 2011-08-24
    Description: Described is the Liulin-5 experiment and instrumentation, developed for investigation of the space radiation doses depth distribution in a human phantom on the Russian Segment of the International Space Station (ISS). Liulin-5 experiment is a part of the international project MATROSHKA-R on ISS. The experiment MATROSHKA-R is aimed to study the depth dose distribution at the sites of critical organs of the human body, using models of human body-anthropomorphic and spherical tissue-equivalent phantoms. The aim of Liulin-5 experiment is long term (4-5 years) investigation of the radiation environment dynamics inside the spherical tissue-equivalent phantom, mounted in different places of the Russian Segment of ISS. Energy deposition spectra, linear energy transfer spectra, flux and dose rates for protons and the biologically-relevant heavy ion components of the galactic cosmic radiation will be measured simultaneously with near real time resolution at different depths of the phantom by a telescope of silicon detectors. Data obtained together with data from other active and passive dosimeters will be used to estimate the radiation risk to the crewmembers, verify the models of radiation environment in low Earth orbit, validate body transport model and correlate organ level dose to skin dose. Presented are the test results of the prototype unit. The spherical phantom will be flown on the ISS in 2004 year and Liulin-5 experiment is planned for 2005 year. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 34; 6; 1297-301
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  • 86
    Publication Date: 2011-08-24
    Description: Space flight results in the exposure of astronauts to a mixed field of radiation composed of energetic particles of varying energies, and biological indicators of space radiation exposure provides a better understanding of the associated long-term health risks. Current methods of biodosimetry have employed the use of cytogenetic analysis for biodosimetry, and more recently the advent of technological progression has led to advanced research in the use of genomic and proteomic expression profiling to simultaneously assess biomarkers of radiation exposure. We describe here the technical advantages of the Luminex(TM) 100 system relative to traditional methods and its potential as a tool to simultaneously profile multiple proteins induced by ionizing radiation. The development of such a bioassay would provide more relevant post-translational dynamics of stress response and will impart important implications in the advancement of space and other radiation contact monitoring. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 34; 6; 1362-7
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  • 87
    Publication Date: 2011-08-24
    Description: In cells irradiation by heavy ions has been hypothesized to produce microlesions, regions of local damage. In cell membranes this damage is thought to manifest itself in the form of holes. The primary evidence for microlesions comes from morphological studies of cell membranes, but this evidence is still controversial, especially since holes also have been observed in membranes of normal, nonirradiated, cells. However, it is possible that damage not associated with histologically discernable disruptions may still occur. In order to resolve this issue, we developed a system for detecting microlesions based on liposomes filled with fluorescent dye. We hypothesized that if microlesions form in these liposomes as the result of irradiation, then the entrapped dye will leak out into the surrounding medium in a measurable way. Polypropylene vials containing suspensions of vesicles composed of either dipalmitoyl phosphatidylcholine, or a combination of egg phosphatidylcholine and cholesterol were irradiated at the Brookhaven National Laboratory using 56Fe ions at 1 GeV/amu. In several cases we obtained a significant loss of the entrapped dye above the background level. Our results suggest that holes may form in liposomes as the result of heavy ion irradiation, and that these holes are large enough to allow leakage of cell internal contents that are at least as large as a 1 nm diameter calcein molecule. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
    Keywords: Life Sciences (General)
    Type: Advances in space research : the official journal of the Committee on Space Research (COSPAR); Volume 34; 6; 1373-7
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  • 88
    Publication Date: 2011-08-24
    Description: Radiation-induced chromosome translocations remain in peripheral blood cells over many years, and can potentially be used to measure retrospective doses or prolonged low-dose rate exposures. However, several recent studies have indicated that some individuals possess clones of cells with balanced chromosome abnormalities, which can result in an overestimation of damage and, therefore, influence the accuracy of dose calculations. We carefully examined the patterns of chromosome damage found in the blood lymphocytes of twelve astronauts, and also applied statistical methods to screen for the presence of potential clones. Cells with clonal aberrations were identified in three of the twelve individuals. These clonal cells were present in samples collected both before and after space flight, and yields are higher than previously reported for healthy individuals in this age range (40-52 years of age). The frequency of clonal damage appears to be even greater in chromosomes prematurely condensed in interphase, when compared with equivalent analysis in metaphase cells. The individuals with clonal aberrations were followed-up over several months and the yields of all clones decreased during this period. Since clonal aberrations may be associated with increased risk of tumorigenesis, it is important to accurately identify cells containing clonal rearrangements for risk assessment as well as biodosimetry. Copyright 2003 S. Karger AG, Basel.
    Keywords: Life Sciences (General)
    Type: Cytogenetic and genome research (ISSN 1424-8581); Volume 104; 1-4; 245-51
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  • 89
    Publication Date: 2011-08-24
    Description: Because of the variability of collagen crosslinks, their use as markers for bone resorption is often criticized. We hypothesized that the variability could be reduced by collecting urine for 24 hours (or longer) instead of using single voids, and by not normalizing to creatinine. Urine samples were collected from 22 healthy subjects during two or more 24-hour periods. Each 24-hour pool and each 2nd void of the day were analyzed for N-telopeptide (NTX), pyridinium (PYD), and deoxypyridinoline (DPD) crosslinks. Data were analyzed by using linear regression. For NTX, R2 for the two, 2nd-void samples (n = 38) was 0.55, whereas R2 for the two 24-hour pools was 0.51 or 0.52, expressed per day or per creatinine. For PYD and DPD, R2 for the 2nd-void samples was 0.26 and 0.18, R2 for the 24-hour pools expressed per day was 0.58 and 0.74, and R2 for the 24-hour pools expressed per creatinine was 0.65 and 0.76, respectively. Regression of the 2nd void and the corresponding 24-hour pool, expressed per day, yielded R2 = 0.19, 0.19, and 0.08, for NTX, PYD, and DPD, respectively (n = 76 each). For the 2nd-void sample and its corresponding 24-hour pool, expressed per creatinine, R2 = 0.24, 0.33, and 0.08, respectively. In a separate study, the coefficient of variation for NTX was reduced (P 〈 0.05) when data from more than one 24-hour collection were combined. Thus, the variability inherent in crosslink determinations can be reduced by collecting urine for longer periods. In research studies, the high variability of single-void collections, compounded by creatinine normalization, may alter or obscure findings.
    Keywords: Life Sciences (General)
    Type: Calcified tissue international (ISSN 0171-967X); Volume 74; 4; 336-41
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  • 90
    Publication Date: 2011-08-24
    Description: Air passenger miles will likely double by year 2020. The altered and restrictive environment in an airliner cabin can influence haematological homeostasis in passengers and crew. Flight-related deep venous thromboemboli (DVT) have been associated with at least 577 deaths on 42 of 120 airlines from 1977 to 1984 (25 deaths/million departures), whereas many such cases go unreported. However, there are four major factors that could influence formation of possible flight-induced DVT: sleeping accommodations (via sitting immobilisation); travellers' medical history (via tissue injury); cabin environmental factors (via lower partial pressure of oxygen and lower relative humidity); and the more encompassing chair-rest deconditioning (C-RD) syndrome. There is ample evidence that recent injury and surgery (especially in deconditioned hospitalised patients) facilitate thrombophlebitis and formation of DVT that may be exacerbated by the immobilisation of prolonged air travel.In the healthy flying population, immobilisation factors associated with prolonged (〉5 hours) C-RD such as total body dehydration, hypovolaemia and increased blood viscosity, and reduced venous blood flow (pooling) in the legs may facilitate formation of DVT. However, data from at least four case-controlled epidemiological studies did not confirm a direct causative relationship between air travel and DVT, but factors such as a history of vascular thromboemboli, venous insufficiency, chronic heart failure, obesity, immobile standing position, more than three pregnancies, infectious disease, long-distance travel, muscular trauma and violent physical effort were significantly more frequent in DVT patients than in controls. Thus, there is no clear, direct evidence yet that prolonged sitting in airliner seats, or prolonged experimental chair-rest or bed-rest deconditioning treatments cause DVT in healthy people.
    Keywords: Life Sciences (General)
    Type: Sports medicine (Auckland, N.Z.) (ISSN 0112-1642); Volume 34; 11; 705-25
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  • 91
    Publication Date: 2011-08-24
    Description: Temperature, pressure, and time have been thought to control the smectite-to-illite (S-I) reaction, an important diagenetic process used for petroleum exploration. We demonstrated that microorganisms can promote the S-I reaction by dissolving smectite through reduction of structural Fe(III) at room temperature and 1 atmosphere within 14 days. This reaction typically requires conditions of 300 degrees to 350 degrees C, 100 megapascals, and 4 to 5 months in the absence of microbial activity. These results challenge the conventional concept of the S-I reaction and of reaction kinetic models.
    Keywords: Life Sciences (General)
    Type: Science (ISSN 0036-8075); Volume 303; 5659; 830-2
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  • 92
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    In:  CASI
    Publication Date: 2004-11-25
    Description: Contents include the following: Why are the mirrors segmented? Why lightweight segmented mirrors? Why cold (cryogenic) mirrors? Why a space telescope? How did NASA go about developing the mirror technology to enable this? Why was beryllium selected for JWST s mirrors? How are the Beryllium mirrors made? What happens to the mirrors once they are complete?
    Keywords: Instrumentation and Photography
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  • 93
    Publication Date: 2011-08-24
    Description: The role of two binocular cues to motion in depth-changing disparity (CD) and interocular velocity difference (IOVD)- was investigated by measuring stereomotion speed discrimination and static disparity discrimination performance (stereoacuity). Speed discrimination thresholds were assessed both for random dot stereograms (RDS), and for their temporally uncorrelated equivalents, dynamic random dot stereograms (DRDS), at relative disparity pedestals of -19, 0, and +19 arcmin. While RDS stimuli contain both CD and IOVD cues, DRDS stimuli carry only CD information. On average, thresholds were a factor of 1.7 higher for DRDS than for RDS stimuli with no clear effect of relative disparity pedestal. Results were similar for approaching and receding targets. Variations in stimulus duration had no significant effect on thresholds, and there was no observed correlation between stimulus displacement and perceived speed, confirming that subjects responded to stimulus speed in each condition. Stereoacuity was equally good for our RDS and DRDS stimuli, showing that the difference in stereomotion speed discrimination performance for these stimuli was not due to any difference in the precision of the disparity cue. In addition, when we altered stereomotion stimulus trajectory by independently manipulating the speeds and directions of its monocular half-images, perceived stereomotion speed remained accurate. This finding is inconsistent with response strategies based on properties of either monocular half-image motion, or any ad hoc combination of the monocular speeds. We conclude that although subjects are able to discriminate stereomotion speed reliably on the basis of CD information alone, IOVD provides a precise additional cue to stereomotion speed perception.
    Keywords: Life Sciences (General)
    Type: Journal of vision (Charlottesville, Va.); Volume 4; 12; 1061-79
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  • 94
    Publication Date: 2011-08-24
    Description: To investigate effects of low dose heavy particle radiation to CNS system, we adopted mouse neonatal brain cells in culture being exposed to heavy ions by HIMAC at NIRS and NSRL at BNL. The applied dose varied from 0.05 Gy up to 2.0 Gy. The subsequent biological effects were evaluated by an induction of apoptosis and neuron survival focusing on the dependencies of the animal strains, SCID, B6, B6C3F1, C3H, used for brain cell culture, SCID was the most sensitive and C3H the least sensitive to particle radiation as evaluated by 10% apoptotic criterion. The LET dependency was compared with using SCID and B6 cells exposing to different ions (H, C, Ne, Si, Ar, and Fe). Although no detectable LET dependency was observed in the high LET (55-200 keV/micrometers) and low dose (〈0.5 Gy) regions. The survivability profiles of the neurons were different in the mouse strains and ions. In this report, a result of memory and learning function to adult mice after whole-body and brain local irradiation at carbon ion and iron ion.
    Keywords: Life Sciences (General)
    Type: Uchu seibutsu kagaku (ISSN 0914-9201); Volume 18; 3; 114-5
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  • 95
    Publication Date: 2011-08-24
    Description: Measurements of chromosome aberrations in peripheral blood lymphocytes are currently the most sensitive and reliable indicator of radiation exposure that can be used for biological dosimetry. This technique has been implemented recently to study radiation exposures incurred by astronauts during space flight, where a significant proportion of the dose is delivered by high-LET particle exposure. Traditional methods for the assessing of cytogenetic damage in mitotic cells collected at one time point after exposure may not be suitable for measuring high-LET radiation effects due to the drastic cell cycle perturbations and interphase cell death induced by this type of exposure. In this manuscript we review the recent advances in methodology used to study high-LET induced cytogenetic effects and evaluate the use of chemically-induced Premature Chromosome Condensation (PCC) as an alternative to metaphase analysis. Published data on the cytogenetic effects of in vitro exposures of high-LET radiation is reviewed, along with biodosimetry results from astronauts after short or long space missions.
    Keywords: Life Sciences (General)
    Type: Uchu seibutsu kagaku (ISSN 0914-9201); Volume 18; 4; 216-23
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  • 96
    Publication Date: 2011-08-24
    Description: We examined the apparent dissociation of perceived length and perceived position with respect to the Muller-Lyer (M-L) illusion. With the traditional (two-chevron) figure, participants made accurate open-loop pointing responses at the endpoints of the shaft, despite the presence of a strong length illusion. This apparently non-Euclidean outcome replicated that of Mack, Heuer, Villardi, and Chambers (1985) and Gillam and Chambers (1985) and contradicts any theory of the M-L illusion in which mislocalization of shaft endpoints plays a role. However, when one of the chevrons was removed, a constant pointing error occurred in the predicted direction, as well as a strong length illusion. Thus, with one-chevron stimuli, perceived length and location were no longer completely dissociated. We speculated that the presence of two opposing chevrons suppresses the mislocalizing effects of a single chevron, especially for figures with relatively short shafts.
    Keywords: Life Sciences (General)
    Type: Perception & psychophysics (ISSN 0031-5117); Volume 66; 7; 1095-104
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  • 97
    Publication Date: 2011-08-24
    Description: The National Aeronautics and Space Administration (NASA) has been conducting controlled environment research with potatoes (Solanum tuberosum L.) in recirculating nutrient film technique (NFT)-hydroponic systems as a human life support component during long-duration spaceflight. Standard nutrient solution management approaches include constant pH regulation with nitric acid (HNO3) and daily adjustment of electrical conductivity (EC) equivalent to half-strength modified Hoagland's solution, where nitrate (NO3-) is the sole nitrogen (N) source. Although tuber yields have been excellent with such an approach, N use efficiency indices are expected to be low relative to tuber biomass production. Furthermore, the high amount of N used in NFT-hydroponics, typically results in high inedible biomass, which conflicts with the need to minimize system mass, volume, and expenditure of resources for long-duration missions. More effective strategies of N fertilization need to be developed to more closely match N supply with demand of the crop. Hence, the primary objective of this study was to identify the optimal N management regime and plant N requirement to achieve high yields and to avoid inefficient use of N and excess inedible biomass production. In separate 84-day cropping experiments, three N management protocols were tested. Treatments which decreased NO3(-)-N supply indirectly through lowering nutrient solution EC (Expt. I), or disabling pH control, and/or supplying NH4(+)-N (Expt. III) did not significantly benefit tuber yield, but did influence N use efficiency indices. When supplied with an external 7.5 mM NO3(-)-N for the first 42 days after planting (DAP), lowered to 1.0 mM NO3(-)-N during the final 42 days (Expt. II), plants were able to achieve yields on par with plants which received constant 7.5 mM NO3(-)-N (control). By abruptly decreasing N supply at tuber initiation in Expt. II, less N was taken up and accumulated by plants compared to those which received high constant N (control). However, proportionately more plant accumulated N was used (N use efficiency) to produce tuber biomass when N supply was abruptly lowered at tuber initiation in Expt. II. Hence, a hydroponic nutrient solution N management system may be modified to elicit greater plant N-use while maintaining overall high tuber yield as opposed to achieving high tuber yields through excess N supply and shoot growth.
    Keywords: Life Sciences (General)
    Type: Journal of the American Society for Horticultural Science. American Society for Horticultural Science (ISSN 0003-1062); Volume 129; 1; 134-40
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  • 98
    Publication Date: 2011-08-24
    Description: Conducting cell biology experiments in microgravity can be among the most technically challenging events in a biologist's life. Conflicting events of spaceflight include waiting to get manifested, delays in manifest schedules, training astronauts to not shake your cultures and to add reagents slowly, as shaking or quick injection can activate signaling cascades and give you erroneous results. It is important to select good hardware that is reliable. Possible conflicting environments in flight include g-force and vibration of launch, exposure of cells to microgravity for extended periods until hardware is turned on, changes in cabin gases and cosmic radiation. One should have an on-board 1-g control centrifuge in order to eliminate environmental differences. Other obstacles include getting your funding in a timely manner (it is not uncommon for two to three years to pass between notification of grant approval for funding and actually getting funded). That said, it is important to note that microgravity research is worthwhile since all terrestrial life evolved in a gravity field and secrets of biological function may only be answered by removing the constant of gravity. Finally, spaceflight experiments are rewarding and worth your effort and patience.
    Keywords: Life Sciences (General)
    Type: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology (ISSN 1077-9248); Volume 11; 1; 105-9
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  • 99
    Publication Date: 2011-08-24
    Description: The present work tested whether the relationship between functional traits and inoculum density reflected structural diversity in bacterial communities from a land-use intensification gradient applying a mathematical model. Terminal restriction fragment length polymorphism (T-RFLP) analysis was also performed to provide an independent assessment of species richness. Successive 10-fold dilutions of a soil suspension were inoculated onto Biolog GN(R) microplates. Soil bacterial density was determined by total cell and plate counts. The relationship between phenotypic traits and inoculum density fit the model, allowing the estimation of maximal phenotypic potential (Rmax) and inoculum density (KI) at which Rmax will be half-reduced. Though Rmax decreased with time elapsed since clearing of native vegetation, KI remained high in two of the disturbed sites. The genetic pool of bacterial community did not experience a significant reduction, but the active fraction responding in the Biolog assay was adversely affected, suggesting a reduction in the functional potential. c2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
    Keywords: Life Sciences (General)
    Type: FEMS microbiology ecology (ISSN 0168-6496); Volume 49; 2; 253-9
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  • 100
    Publication Date: 2011-08-24
    Description: The primary mission of the Cellular Biotechnology Program is to advance microgravity as a tool in basic and applied cell biology. The microgravity environment can be used to study fundamental principles of cell biology and to achieve specific applications such as tissue engineering. The Biotechnology Facility (BTF) will provide a state-of-the-art facility to perform cellular biotechnology research onboard the International Space Station (ISS). The BTF will support continuous operation, which will allow performance of long-duration experiments and will significantly increase the on-orbit science throughput.
    Keywords: Life Sciences (General)
    Type: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology (ISSN 1077-9248); Volume 11; 1; 75-80
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