Publication Date:
1995-11-24
Description:
Arthropods exhibit great diversity in the position, number, morphology, and function of their limbs. The evolutionary relations among limb types and among the arthropod groups that bear them (insects, crustaceans, myriapods, and chelicerates) are controversial. Here, the use of molecular probes, including an antibody to proteins encoded by arthropod and vertebrate Distal-less (Dll and Dlx) genes, provided evidence that common genetic mechanisms underlie the development of all arthropod limbs and their branches and that all arthropods derive from a common ancestor. However, differences between crustacean and insect body plans were found to correlate with differences in the deployment of particular homeotic genes and in the ways that these genes regulate limb development.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Panganiban, G -- Sebring, A -- Nagy, L -- Carroll, S -- New York, N.Y. -- Science. 1995 Nov 24;270(5240):1363-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Molecular Biology, University of Wisconsin, Madison 53706, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7481825" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
Animals
;
Artemia/genetics/growth & development
;
Arthropods/embryology/genetics/*growth & development
;
Base Sequence
;
*Biological Evolution
;
Cell Differentiation
;
Crustacea/embryology/genetics/*growth & development
;
Decapoda (Crustacea)/embryology/genetics/growth & development
;
Extremities/embryology/growth & development
;
*Gene Expression Regulation, Developmental
;
*Genes, Homeobox
;
Homeodomain Proteins/genetics/immunology
;
Molecular Sequence Data
;
Morphogenesis
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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