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  • General Chemistry  (859)
  • Life and Medical Sciences  (479)
  • Cell & Developmental Biology  (362)
  • Humans  (276)
  • 1975-1979  (1,614)
  • 1979  (1,614)
Collection
Keywords
Publisher
Years
  • 1975-1979  (1,614)
Year
  • 101
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    Tectorial membrane: a possible effect on frequency analysis in the cochlea (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: Mathematical analysis and computer and network simulations of the cochlea show that, given appropriate values of specific physical constants, radial shear motion between the tectorial membrane and the reticular lamina may provide the sharpening of frequency analysis observed in cochlear nerve fibers in comparison with the mechanical amplitude distribution on the basilar membrane. According to the analysis, the sharpening occurs through an interaction of the longitudinal mechanical propagation constant of the tectorial membrane with the wavelength on the basilar membrane.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zwislocki, J J -- Kletsky, E J -- New York, N.Y. -- Science. 1979 May 11;204(4393):639-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432671" target="_blank"〉PubMed〈/a〉
    Keywords: Basilar Membrane/*physiology ; Biomechanical Phenomena ; Cochlea/*physiology ; Ear, Inner/*physiology ; Hair Cells, Auditory/*physiology ; Hearing/*physiology ; Humans ; Mechanoreceptors/*physiology ; Models, Biological ; Tectorial Membrane/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 102
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    Phase advance of the circadian sleep-wake cycle as an antidepressant (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-09
    Description: Sleep in depressed patients resembles sleep in normal subjects whose circadian rhythms of temperature and rapid-eye-movement sleep are phase-advanced (shifted earlier) relative to their sleep schedules. If this analogy is relevant to the pathophysiology of depressive illness, advancing the time of sleep and awakening should temporarily compensate for the abnormal timing of depressed patients' circadian rhythms. Four of seven manic-depressive patients studied longitudinally spontaneously advanced their times of awakening (activity onset) as they emerged from the depressive phase of their illness. In a phase-shift experiment, a depressed manic-depressive woman was twice brought out of depression for 2 weeks by advancing her sleep period so that she went to sleep and arose 6 hours earlier than usual. The antidepressant effect of the procedure was temporary and similar in duration to circadian desynchronization induced by jet lag in healthy subjects. This result supports the hypothesis that abnormalities of sleep patterns in some types of depression are due to abnormal internal phase relationships of circadian rhythms.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wehr, T A -- Wirz-Justice, A -- Goodwin, F K -- Duncan, W -- Gillin, J C -- New York, N.Y. -- Science. 1979 Nov 9;206(4419):710-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/227056" target="_blank"〉PubMed〈/a〉
    Keywords: Bipolar Disorder/*physiopathology/therapy ; Body Temperature Regulation ; *Circadian Rhythm ; Female ; Humans ; Middle Aged ; Motor Activity/physiology ; Sleep, REM/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 103
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    Surgeon general seeks physicians' help in DES alert (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1979 Jan 12;203(4376):159.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758685" target="_blank"〉PubMed〈/a〉
    Keywords: Diethylstilbestrol/*adverse effects ; Drug Information Services ; Female ; Government Agencies ; Humans ; Mesonephroma/*chemically induced ; United States ; Vaginal Neoplasms/*chemically induced
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 104
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    Cancer--opportunism and opportunity (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1979 Oct 5;206(4414):11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482924" target="_blank"〉PubMed〈/a〉
    Keywords: *Carcinogens ; Environmental Exposure ; Food ; Humans ; Neoplasms/*etiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 105
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    Effects of anesthesia (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1979 Feb 23;203(4382):705.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/419403" target="_blank"〉PubMed〈/a〉
    Keywords: *Abnormalities, Drug-Induced ; Abortion, Spontaneous/*chemically induced ; Anesthetics/*adverse effects ; Female ; Humans ; Male ; Pregnancy
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 106
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    Bitter taste of saccharin related to the genetic ability to taste the bitter substance 6-n-propylthiouracil (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-31
    Description: Bitter taste thresholds for 6-n-propylthiouracil are bimodally distributed, dividing subjects into tasters and nontasters. Their taste worlds differ with regard to the sweetness of sucrose and saccharin and to the bitterness of saccharin. These differences suggest that nontasters tend to perceive less bitterness in saccharin at concentrations used in beverages.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bartoshuk, L M -- New York, N.Y. -- Science. 1979 Aug 31;205(4409):934-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472717" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; *Propylthiouracil ; *Saccharin ; Taste/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 107
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    Psychophysical evidence for a monocular visual cortex in stereoblind humans (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-19
    Description: Human observers who lack stereopsis reliably make eye-of-origin discriminations for grating patterns under conditions that render the performance of normal observers unreliable. This lends support to the view that stereoblind individuals possess proportions of monocular and binocular cortical cells similar to those of cats and monkeys deprived of early binocular visual experience.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Blake, R -- Cormack, R H -- New York, N.Y. -- Science. 1979 Jan 19;203(4377):274-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760194" target="_blank"〉PubMed〈/a〉
    Keywords: Depth Perception/*physiology ; Humans ; Visual Cortex/cytology/*physiology ; Visual Pathways/cytology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 108
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    Orientation anisotropy of visual stimuli in rhesus monkey: a behavior study (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-03
    Description: The contrast sensitivity of the rhesus monkey was tested, according to a modified reaction-time paradigm, for sine-wave grating targets at different orientations. The monkey possesses an oblique effect slightly larger than that of humans. A reaction time analysis showed the oblique effect to be a suprathreshold as well as a threshold phenomenon. The presence of this effect further strengthens the use of the monkey as a model for the human visual system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boltz, R L -- Harwerth, R S -- Smith, E L 3rd -- R01 EY001139/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1979 Aug 3;205(4405):511-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/109923" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal ; Haplorhini ; Humans ; Macaca mulatta ; Species Specificity ; *Visual Perception
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 109
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    Jump in funding feeds research on nutrition (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1060-1, 1063-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451549" target="_blank"〉PubMed〈/a〉
    Keywords: *Diet ; Disease ; Government Agencies ; Humans ; Legislation as Topic ; *Nutritional Physiological Phenomena ; Research Support as Topic ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 110
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    Yearly report on carcinogens could be a potent weapon in the war on cancer (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):525-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760203" target="_blank"〉PubMed〈/a〉
    Keywords: *Carcinogens ; Dose-Response Relationship, Drug ; Government Agencies ; Humans ; Legislation, Drug ; Neoplasms/*prevention & control ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 111
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    Menopausal flushes: a neuroendocrine link with pulsatile luteninizing hormone secreation (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: Menopausal flush episodes were found to be invariably associated with the initiation of pulsatile pituitary release of luteinizing hormone. This was not accompanied by a significant change in circulating catecholamine or prolactin concentrations. Since pulsatile luteinizing hormone release results from episodic secretion of luteinizing hormone releasing factor by the hypothalamus, these findings suggest a link between the neuroendocrine mechanisms that initiate such episodic secretion and those responsible for the onset of flush episodes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Casper, R F -- Yen, S S -- Wilkes, M M -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):823-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462193" target="_blank"〉PubMed〈/a〉
    Keywords: *Climacteric ; Dopamine/blood ; Epinephrine/blood ; Female ; Follicle Stimulating Hormone/blood ; Humans ; Luteinizing Hormone/blood/*secretion ; Middle Aged ; Norepinephrine/blood ; Prolactin/blood
    Print ISSN: 0036-8075
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  • 112
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    Protein deficiency and tribal warfare in Amazonia: new data (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-02
    Description: Increasing numbers of anthropological studies about native Amazonian warfare and demographic practices attempt to explain these phenomena as competition over or a response to scarce game animals and other sources of high-quality protein. Recently completed field research among the Yanomamo Indians living at the Venezuela-Brazil border indicates that their protein intake is comparable to that found in highly developed industrialized nations and as much as 200 percent more than many nutritional authorities recommend as daily allowances. Recent data on other Amazonian tribes likewise fails to indicate a correlation between protein intake and intensity of warfare patterns.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chagnon, N A -- Hames, R B -- New York, N.Y. -- Science. 1979 Mar 2;203(4383):910-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/570302" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Wild ; Behavior/physiology ; Brazil ; Dietary Proteins/*metabolism ; Energy Intake ; Fishes ; Humans ; *Indians, South American ; Meat ; Warfare
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 113
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    Inhibition of histaminase release from human granulocytes by products of histaminase activity (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-05
    Description: Imidazoleacetic acid, a product of the action of histaminase (E.C. 1.4.3.6) on histamine, inhibits specific release of histaminase from human peripheral blood granulocytes with an inhibition constant between 5 X 10(-9)M and 1 X 10(-8)M. Hence, modulation of enzyme release is indirectly mediated by the activity of the enzyme.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Herman, J J -- Brenner, J K -- Colten, H R -- New York, N.Y. -- Science. 1979 Oct 5;206(4414):77-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/113872" target="_blank"〉PubMed〈/a〉
    Keywords: Acetates/pharmacology ; Amine Oxidase (Copper-Containing)/*blood ; Biological Transport/drug effects ; Feedback ; Granulocytes/*enzymology ; Humans ; Imidazoles/*pharmacology ; Kinetics
    Print ISSN: 0036-8075
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  • 114
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    N-nitrosamines in the rubber and tire industry (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-21
    Description: Airborne N-nitrosomorpholine (0 to 27 micrograms per cubic meter) was found in two of four rubber industry factories. N-Nitrosodimethylamine was also found in two factories, but at lower levels. These findings may be relevant to the reported increased risk of certain types of cancer in rubber workers in some of the same areas where the N-nitrosomorpholine levels were highest.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fajen, J M -- Carson, G A -- Rounbehler, D P -- Fan, T Y -- Vita, R -- Goff, U E -- Wolf, M H -- Edwards, G S -- Fine, D H -- Reinhold, V -- Biemann, K -- New York, N.Y. -- Science. 1979 Sep 21;205(4412):1262-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472741" target="_blank"〉PubMed〈/a〉
    Keywords: Air Pollutants/*analysis ; Air Pollutants, Occupational/*analysis ; Dimethylnitrosamine/analysis ; Environmental Exposure ; Humans ; Morpholines/analysis ; Nitrosamines/*analysis ; *Occupational Medicine ; *Rubber
    Print ISSN: 0036-8075
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  • 115
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    Immunocompetence in the lowest metazoan phylum: transplantation immunity in sponges (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-27
    Description: Isografts of Callyspongia diffusa fuse compatibly, but allografts are invariably incompatible. Extensive polymorphism of cell-surface histocompatibility markers is evident. The histocompatibility barriers range from strong to weak depending on the interclonal combination, but early rejection with conspicous cytotoxic sequelae is typical. Reaction times of first-set, second-set, and third-party grafts indicate highly discriminating transplantation immunity with a specific memory component.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hildemann, W H -- Johnson, I S -- Jokiel, P L -- New York, N.Y. -- Science. 1979 Apr 27;204(4391):420-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441730" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Histocompatibility Antigens ; Humans ; Immunologic Memory ; Porifera/*immunology ; *Transplantation Immunology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 116
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    Albert-Szent-Gyorgyi, electrons, and cancer (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):522-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/366748" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Division ; Electrons ; Electrophysiology ; Free Radicals ; History, 20th Century ; Humans ; Hungary ; Massachusetts ; Neoplasms/*physiopathology ; Pyruvaldehyde/metabolism ; Research Support as Topic
    Print ISSN: 0036-8075
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  • 117
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    Low-level radiation: a high-level concern (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1979 Apr 13;204(4389):155-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432637" target="_blank"〉PubMed〈/a〉
    Keywords: Dose-Response Relationship, Radiation ; Government Agencies ; Humans ; Maximum Allowable Concentration ; Neoplasms, Radiation-Induced/*etiology ; Occupational Diseases/etiology ; Research Support as Topic ; Risk
    Print ISSN: 0036-8075
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  • 118
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    Comparisons of frogs, humans, and chimpanzees (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Findley, J S -- New York, N.Y. -- Science. 1979 Apr 27;204(4391):434-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441733" target="_blank"〉PubMed〈/a〉
    Keywords: Amphibians/anatomy & histology ; Animals ; Anura ; Biological Evolution ; Classification/*methods ; Genotype ; Humans ; Phenotype ; Primates/anatomy & histology
    Print ISSN: 0036-8075
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  • 119
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    Heroin study at Georgetown (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1979 Jan 19;203(4377):249.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/83673" target="_blank"〉PubMed〈/a〉
    Keywords: Heroin/*therapeutic use ; Humans ; Neoplasms/drug therapy ; Palliative Care/*methods
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 120
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    [Interpreting "imitative" responses in early infancy] (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jacobson, S W -- Kagan, J -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):215-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451595" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/*physiology ; Female ; Humans ; *Infant ; *Infant, Newborn ; Male ; Movement ; Tongue/physiology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 121
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    Holographic assessment of a hypothesized microwave hearing mechanism (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-12
    Description: Exposure of the head to pulse-modulated microwaves induces the perception of a sound. It has been hypothesized that the electromagnetic energy is converted to acoustic energy in the skull and then conducted through the bone. Dynamic time-averaged interferometric holography showed that the predicted motion of head tissue did not occur. An alternative locus for this hearing effect is suggested.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Frey, A H -- Coren, E -- New York, N.Y. -- Science. 1979 Oct 12;206(4415):232-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482939" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Auditory Perception/*physiology ; Bone and Bones/radiation effects ; Cochlea/physiology/radiation effects ; Guinea Pigs ; Hearing/*physiology ; Holography ; Humans ; *Microwaves ; Models, Biological ; Motion ; Rats ; Vibration
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Nonpneumonic, short-incubation-period Legionellosis (Pontiac fever) in men who cleaned a steam turbine condenser (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-17
    Description: Pontiac fever affected ten men who had cleaned a steam turbine condenser with compressed air. Previous epidemics of Pontiac fever and Legionnaires' disease--both caused by Legionella Pneumophila (proposed sp. nov.)--involved "airborne spread" from air-conditioning cooling towers or evaporative condensers. Aerosols of contaminated water in heat-rejection systems appear to be important sources of epidemic legionellosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fraser, D W -- Deubner, D C -- Hill, D L -- Gilliam, D K -- New York, N.Y. -- Science. 1979 Aug 17;205(4407):690-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462175" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Air Microbiology ; Humans ; Legionnaires' Disease/*etiology/microbiology/transmission ; Male ; Occupational Medicine ; Time Factors
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    Determinants of cognitive performance in Warsaw (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lasky, R E -- New York, N.Y. -- Science. 1979 Nov 2;206(4418):600.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493966" target="_blank"〉PubMed〈/a〉
    Keywords: Cognition/*physiology ; Environment ; Humans ; Poland
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    Rhythms in human performance: 1 1/2-hour oscillations in cognitive style (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: Performance on verbal and spatial matching tasks was assessed every 15 minutes for 8 hours. Significant 60- to 100-minute oscillations were observed for each task. These oscillations were 180 degrees out of phase, supporting the hypothesis that in humans the basic rest activity cycle involves alternating activation of processing systems residing in the two cerebral hemispheres.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klein, R -- Armitage, R -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1326-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451541" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/*physiology ; Brain/*physiology ; *Circadian Rhythm ; Cognition/*physiology ; *Functional Laterality ; Humans ; Verbal Behavior/physiology
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    Humans deprived of normal binocular vision have binocular interactions tuned to size and orientation (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-16
    Description: A suprathreshold grating presented to one eye elevated the threshold for the discrimination of gratings similar in size and orientation presented to the fellow eye. The magnitude and stimulus specificity of these binocular interactions in human observers with normal bioncular vision were similar to those in observers deprived of normal binocular visual experience; however, the latter showed a failure of binocular summation at threshold or subthreshold contract levels. Whereas strabismus or amblyopia disrupted the normal excitatory interactions between the two eyes, cortical inhibitory binocular connections seem not to have been disrupted.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levi, D M -- Harwerth, R S -- Smith, E L 3rd -- R01 EY001139/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1979 Nov 16;206(4420):852-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493988" target="_blank"〉PubMed〈/a〉
    Keywords: Amblyopia/*physiopathology ; Humans ; Orientation/physiology ; Size Perception/physiology ; Strabismus/*physiopathology ; *Vision, Ocular ; Visual Pathways/physiology/physiopathology ; Visual Perception/*physiology
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    Perception of size of one object among many (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: Adaptation to a grating of properly chosen frequency may lead to two apparently conflicting observations: Another grating may then appear to be of increased frequency (compared with its "unadapted" frequency) while the individual bars of the grating appear to have widened. This perceived widening parallels previous results with single bars. By attending to only one grating bar, the subject effectively seems to change the grating frequency spectrum to that of a single bar.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levinson, J Z -- Frome, F S -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1425-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505017" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptation, Physiological ; Humans ; Size Perception/*physiology ; Visual Fields ; Visual Perception/*physiology
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    "Uninformed consent" (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marcus, R B -- Kuklick, B -- Bercovitch, S -- New York, N.Y. -- Science. 1979 Aug 17;205(4407):644,646-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/379997" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Trials as Topic ; Disclosure ; Humans ; *Informed Consent ; Personal Autonomy ; Placebos ; Psychology ; *Risk Assessment
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    Mutual repulsion between moving visual targets (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: When two spatially intermingled sets of random dots move in different directions, the direction of each set may be misperceived. Observers report that each set of dots appears to move in a direction displaced by as much as 20 degrees from the direction of its companion set. Probably the result of inhibitory interactions, this mutual repulsion occurs at a central site in the visual system and may normally enhance discrimination of direction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshak, W -- Sekuler, R -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1399-401.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472756" target="_blank"〉PubMed〈/a〉
    Keywords: Eye Movements ; Humans ; Motion Perception/*physiology ; Neural Inhibition ; Ocular Physiological Phenomena ; Visual Perception/*physiology
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    Parabolic flight: loss of sense of orientation (1979)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1979-11-30
    Description: On the earth, or in level flight, a blindfolded subject being rotated at constant velocity about his recumbent long body axis experiences illusory orbital motion of his body in the opposite direction. By contrast, during comparable rotation in the free-fall phase of parabolic flight, no body motion is perceived and all sense of external orientation may be lost; when touch and pressure stimulation is applied to the body surface, a sense of orientation is reestablished immediately. The increased gravitoinertial force period of a parabola produces an exaggeration of the orbital motion experienced in level flight. These observations reveal an important influence of touch, pressure, and kinesthetic information on spatial orientation and provide a basis for understanding many of the postural illusions reported by astronauts in space flight.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lackner, J R -- Graybiel, A -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1105-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493998" target="_blank"〉PubMed〈/a〉
    Keywords: Acceleration ; *Aerospace Medicine ; Eye Movements ; Gravitation ; Humans ; Illusions ; Kinesis/physiology ; *Orientation ; Posture ; Pressure ; Touch/physiology
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    Blood substitute passes its first test (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1979 Oct 12;206(4415):205.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482936" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Emulsions ; Fluorocarbons/*therapeutic use ; Humans ; Male ; Plasma Substitutes/*therapeutic use
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    Dysmenorrhea: basic research leads to a rational therapy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):175-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/109921" target="_blank"〉PubMed〈/a〉
    Keywords: Cyclooxygenase Inhibitors ; Dysmenorrhea/drug therapy/*physiopathology ; Female ; Humans ; Progesterone/physiology ; Prostaglandins/*physiology ; Uterine Contraction
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    Research subjects: rights and regulations (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McCarthy, C R -- New York, N.Y. -- Science. 1979 Aug 31;205(4409):855-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/382354" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Trials as Topic ; Humans ; Jurisprudence ; Research/*standards
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    Galactosemia: alterations in sulfate metabolism secondary to galactose-1-phosphate uridyltransferase deficiency (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: Cultures of nonmutant as well as galactokinase-deficient fibroblasts incorporate 20 percent more [35S]sulfate when galactose is substituted for glucose in the medium; galactose-1-phosphate uridyltransferase-deficient cells incorporate 65.5 percent less. In addition to incorporating less [35S]sulfate, the uridyltransferase-deficient cells showed significant accumulation of intracellular galactose-1-phosphate within 4 hours after galactose exposure. Under the same conditions, no difference in [3H]uridine incorporation was observed. This metabolic alteration, occurring in response to galactose exposure, may be related to the pathophysiology of classical galactosemia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tedesco, T A -- Miller, K L -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1395-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472754" target="_blank"〉PubMed〈/a〉
    Keywords: Cells, Cultured ; Galactose/metabolism ; Galactosemias/*metabolism ; Galactosephosphates/metabolism ; Glucose/metabolism ; Humans ; Nucleotidyltransferases/*deficiency ; Sulfates/*metabolism ; UTP-Hexose-1-Phosphate Uridylyltransferase/*deficiency
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    Can an ape create a sentence? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-23
    Description: More than 19,000 multisign utterances of an infant chimpanzee (Nim) were analyzed for syntactic and semantic regularities. Lexical regularities were observed in the case of two-sign combinations: particular signs (for example, more) tended to occur in a particular position. These regularities could not be attributed to memorization or to position habits, suggesting that they were structurally constrained. That conclusion, however, was invalidated by videotape analyses, which showed that most of Nim's utterances were prompted by his teacher's prior utterance, and that Nim interrupted his teachers to a much larger extent than a child interrupts an adult's speech. Signed utterances of other apes (as shown on films) revealed similar non-human patterns of discourse.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Terrace, H S -- Petitto, L A -- Sanders, R J -- Bever, T G -- New York, N.Y. -- Science. 1979 Nov 23;206(4421):891-902.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504995" target="_blank"〉PubMed〈/a〉
    Keywords: *Animal Communication ; Animals ; Humans ; Language Development ; Male ; Pan troglodytes/*physiology ; Semantics ; Sign Language ; Time Factors
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    Triglyceride concentrations: the disaccharide effect (1979)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1979-11-16
    Description: The mean 24-hour or integrated concentration of triglyceride is significantly higher when dietary sucrose is provided rather than an equivalent amount of its component monosaccharides, glucose and fructose. In contrast, the plasma triglyceride concentration after a 12-hour fast is not significantly different.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Thompson, R G -- Hayford, J T -- Hendrix, J A -- New York, N.Y. -- Science. 1979 Nov 16;206(4420):838-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493983" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Dietary Carbohydrates/*metabolism ; Fructose/metabolism ; Glucose/metabolism ; Humans ; Male ; Sucrose/metabolism ; Triglycerides/*blood
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    Phenacetin studies (1979)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1979-11-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vaught, J B -- King, C M -- New York, N.Y. -- Science. 1979 Nov 9;206(4419):637, 639.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493967" target="_blank"〉PubMed〈/a〉
    Keywords: Acute Kidney Injury/chemically induced ; Animals ; Biotransformation ; *Carcinogens ; Humans ; Kidney Neoplasms/chemically induced ; Mice ; Mutation ; Phenacetin/*adverse effects/metabolism
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    Semliki forest virus: cause of a fatal case of human encephalitis (1979)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1979-03-16
    Description: A fatal case of human encephalitis has been observed for which our results indicate that Semliki Forest virus (SFV) was the etiologic agent. This is surprising in view of the fact that this virus, which has been widely studied, was believed to be one of the arboviruses nonpathogenic for man. Described are the clinical course, the virological examinations performed, and the histopathological findings in the central nervous system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Willems, W R -- Kaluza, G -- Boschek, C B -- Bauer, H -- Hager, H -- Schutz, H J -- Feistner, H -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1127-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424742" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Antigens, Viral/analysis ; Arbovirus Infections/*etiology ; Encephalitis/*etiology/microbiology/pathology ; Female ; Humans ; Laboratory Infection/*etiology/microbiology ; *Semliki forest virus/immunology
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    The psychophysical function: harmonizing Fechner and Stevens (1979)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1979-04-06
    Description: The methods of Fechner and Stevens for assessing sensation quantity usually yield different psychophysical functions even when all other factors are controlled. In this experiment, corresponding differences occurred when different features of the same sensory receptor signals were analyzed. In the visual system, the receptor potential saturated if the peak but not the area was measured; these results match visual psychophysical functions obtained with the methods of Fechner and Stevens, respectively. This result suggests that both methods are equally valid but that each method yields the particular psychophysical function appropriate for a particular kind of information processing. A novel factor in determining sensation quantity, namely the time used by the observer to make a judgment, is implicated by the data.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wasserman, G S -- Felsten, G -- Easland, G S -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):85-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432630" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Dose-Response Relationship, Radiation ; Evoked Potentials ; Horseshoe Crabs ; Humans ; Light ; Models, Neurological ; Photoreceptor Cells/*physiology ; Visual Perception/*physiology
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    Rotaviral immunity in gnotobiotic calves: heterologous resistance to human virus induced by bovine virus (1979)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1979-02-09
    Description: The possibility of immunizing human infants against rotaviruses, which cause severe dehydrating diarrheal disease, may depend on the use of a related rotavirus, derived from another animal species, as a source of antigen. To test the feasibility of this approach, calves were infected in utero with a bovine rotavirus and challenged with bovine or human type 2 rotavirus shortly after birth. Infection in utero with bovine rotavirus induced resistance to diarrheal disease caused by the human virus as well as the homologous bovine virus. These data suggest that the bovine virus is sufficiently related antigenically to the human type 2 virus to warrant further evaluation of the former as a source of vaccine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wyatt, R G -- Mebus, C A -- Yolken, R H -- Kalica, A R -- James, H D Jr -- Kapikian, A Z -- Chanock, R M -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):548-50.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/216077" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Newborn/immunology ; Cattle ; Cross Reactions ; Diarrhea, Infantile/prevention & control ; Germ-Free Life ; Humans ; Immunization ; RNA Viruses/*immunology ; Rotavirus/*immunology ; Species Specificity ; Viral Vaccines/immunology ; Virus Diseases/*prevention & control
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    The hyperactive child syndrome (1979)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1979-09-28
    Description: The behavioral characteristics of the hyperactive child are described at different stages of development. Recent and sometimes controversial research findings are discussed with respect to prevalence, etiology, treatment, and outcome. It is concluded that this syndrome can best be understood in terms of interactions between social, psychological, and biological variables.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weiss, G -- Hechtman, L -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1348-54.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472752" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Attention Deficit Disorder with Hyperactivity/etiology ; Child ; Child Behavior Disorders/diagnosis/*etiology/therapy ; Child, Preschool ; Environment ; Female ; Humans ; Infant ; Male ; Methylphenidate/therapeutic use ; Sex Ratio ; Syndrome ; Terminology as Topic
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 141
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    Combination tones at frequencies greater than the primary tones (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-10
    Description: The existence of audible combination tones at frequencies greater than the primary tones that generate them has long been problematic. With primary tones at frequencies f1 and f2, combination tones at f1 + f2 - f1, and other frequencies can be demonstrated and measured by using a contralateral probe tone to establish a binaural interaction with a given combination tone. The estimated amplitudes of these higher-frequency combination tones are generally 20 to 40 decibels below the amplitude of the primary tones.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zurek, P M -- Sachs, R M -- New York, N.Y. -- Science. 1979 Aug 10;205(4406):600-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451625" target="_blank"〉PubMed〈/a〉
    Keywords: Acoustic Stimulation ; *Hearing ; Humans ; *Sound
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 142
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    Identifying environmental chemicals causing mutations and cancer (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: Damage to DNA appears to be the major cause of most cancer and genetic birth defects and may contribute to aging and heart disease as well. The agents that cause this damage must be identified. Many of these agents are natural chemicals present in the human diet as complex mixtures. The tens of thousands of man-made chemicals that have been introduced into the environment in the last few decades must also be tested for their ability to damage DNA. Existing animal tests and human epidemiology alone are inadequate for this task because of time, expense, and the difficulty of dealing with complex mixtures, Newly developed short-term tests, most of them assaying for mutagenicity, are discussed as key tools in identifying environmental mutagens and carcinogens.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ames, B N -- New York, N.Y. -- Science. 1979 May 11;204(4393):587-93.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/373122" target="_blank"〉PubMed〈/a〉
    Keywords: *Carcinogens ; DNA/genetics ; Disease Models, Animal ; Environmental Exposure ; Ethylene Dibromide ; Ethylene Dichlorides ; Flame Retardants ; Furylfuramide ; Hair Dyes ; Humans ; Hydrocarbons, Halogenated ; Maximum Allowable Concentration ; Microsomes, Liver/metabolism ; *Mutagens ; Neoplasms/*chemically induced ; Risk ; Salmonella/drug effects ; Smoking/complications ; Time Factors
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 143
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    Physostigmine and recent memory: effects in young and aged nonhuman primates (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: The effect of physostigmine on recent memory was evaluated in young and aged rhesus monkeys. All aged monkeys had previously shown impaired memory. The performance of the young monkeys treated with physostigmine was similar to that recently reported for young humans--no effects at low doses, some improvement at a restricted range of doses, and deficits at the highest dose. Although the aged subjects also improved at the same general doses, their overall response as a group was much more variable than that of the younger subjects. The performance of some aged monkeys was impaired by low doses that did not affect young monkeys. Continued improvement was observed in some aged monkeys at the highest dose, which typically impaired young monkeys. These variable effects across aged subjects suggest that physostigmine cannot easily or reliably be used as an agent for treating geriatric cognition. Nevertheless, the differential age-related effects suggest that appropriate manipulation of the cholinergic system may eventually be developed to alleviate some of the cognitive impairments suffered by aged subjects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bartus, R T -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1087-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/227061" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylcholine/physiology ; Aging ; Animals ; Cognition/physiology ; Female ; Haplorhini ; Humans ; Male ; Memory/*drug effects ; Memory Disorders/drug therapy ; Memory, Short-Term/drug effects ; Physostigmine/*pharmacology/therapeutic use ; Synaptic Transmission
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 144
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    Interpreting "imitative" responses in early infancy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anisfeld, M -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):214-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451593" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/*physiology ; Humans ; *Infant, Newborn ; Methods
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 145
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    Infant perception of visually presented objects (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bower, T G -- Dunkeld, J -- Wishart, J G -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1137-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424745" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/physiology ; Humans ; *Infant, Newborn ; Visual Pathways/growth & development/physiology ; Visual Perception/*physiology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 146
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    Fetal research ethics (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brackbill, Y -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):404-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504983" target="_blank"〉PubMed〈/a〉
    Keywords: Abortion, Induced ; Disclosure ; *Ethics, Medical ; Female ; Fetus/*physiology ; Humans ; Informed Consent ; Pregnancy ; *Risk Assessment
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  • 147
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    High anxiety over flights through ozone (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):767, 769.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462189" target="_blank"〉PubMed〈/a〉
    Keywords: *Aerospace Medicine ; Female ; Humans ; Male ; Occupational Diseases/*chemically induced ; Ozone/*poisoning
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  • 148
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    Cancer and industrial chemical production (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davis, D L -- Magee, B H -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1356, 1358.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505010" target="_blank"〉PubMed〈/a〉
    Keywords: Environmental Exposure ; Humans ; *Industry ; Neoplasms/*chemically induced/epidemiology ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 149
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    Legionnaires' disease: concentrations of selenium and other elements (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: Selenium concentrations in the serums of 17 acutely ill Legionnaires' disease patients were significantly lower than in their matching convalescent-phase serums. This trend was not observed in ten similarly paired samples of serum from control patients with pneumonia. There were no significant differences in the concentrations of nickel, copper, bromine, rubidium, lead, barium, or titanium in the serums of Legionnaires' disease and control patients.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, J R -- Anderson, J M -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1426-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505018" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Legionnaires' Disease/*blood ; Metals/blood ; Nickel/blood ; Selenium/*blood
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 150
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    To know with the nose: keys to odor identification (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-02
    Description: Successful odor identification depends on (i) commonly encountered substances, (ii) a long-standing connection between an odor and its name, and (iii) aid in recalling the name. The absence of any one ingredient impairs performance dramatically, but the presence of all three permits ready identification of scores of substances, with performance seemingly limited only by the inherent confusability of the stimuli.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cain, W S -- New York, N.Y. -- Science. 1979 Feb 2;203(4379):467-70.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760202" target="_blank"〉PubMed〈/a〉
    Keywords: Feedback ; Female ; Humans ; Memory/physiology ; Odors ; Smell/*physiology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 151
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    Laterality for stereognostic accuracy of children for words, shapes, and bigrams: a sex difference for bigrams (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: Children identified nonsense shapes by touch better with their left hand and words better with their right hand. Bigrams were processed by boys as shapes and by girls as words, which suggests a sexual dimorphism of brain functioning for bigrams. A relative specialization of the hemisphere for stereognostic processing is also suggested, since the accuracy of identification by both hands was greater than chance for all three types of stimuli.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cioffi, J -- Kandel, G L -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1432-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451575" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Age Factors ; Child ; Cognition/physiology ; Form Perception/*physiology ; *Functional Laterality ; Humans ; Pattern Recognition, Visual/*physiology ; Perception/*physiology ; Sex Factors ; Touch/*physiology
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  • 152
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    Food deprivation increases oral and intravenous drug intake in rats (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: Rats given continuous access to etonitazene hydrochloride in their drinking water (5 micrograms per milliliter) more than doubled their drug intake while deprived of food. Another group of rats with implanted jugular catheters self-administered etonitazene (10 micrograms per kilogram) intravenously on a continuous reinforcement schedule, and the number of infusions increased significantly on days when they were deprived of food. These results suggest that feeding condition may be a powerful determinant of drug-reinforced behavior.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carroll, M E -- France, C P -- Meisch, R A -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):319-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/36665" target="_blank"〉PubMed〈/a〉
    Keywords: Administration, Oral ; Animals ; Benzimidazoles/*administration & dosage ; Drinking Behavior ; *Food Deprivation ; Humans ; Injections, Intravenous ; Male ; Rats ; Self Administration ; Stereotyped Behavior/physiology
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  • 153
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    Recombinant DNA policy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dach, Leslie -- Lazell, James D -- New York, N.Y. -- Science. 1979 Jan 26;203(4378):314+.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11643488" target="_blank"〉PubMed〈/a〉
    Keywords: Biology ; Consumer Participation ; *DNA, Recombinant ; Ecology ; Federal Government ; Government ; Government Regulation ; Humans ; *Organizational Policy ; Research Personnel ; Social Control, Formal ; *Societies
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  • 154
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    Reducing epileptic seizures through operant conditioning of central nervous system activity: procedural variables (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: Operant conditioning of the sensorimotor rhythm of the human electroencephalogram with time-outs contingent on epileptiform activity reduces epileptic seizure rates in patients whose seizures are not well controlled by medication. A comparison of this procedure with time-out training alone demonstrates that operant conditioning of the sensorimotor rhythm is neither necessary nor sufficient for seizure reduction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cott, A -- Pavloski, R P -- Black, A H -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):73-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758682" target="_blank"〉PubMed〈/a〉
    Keywords: Biofeedback, Psychology/*physiology ; Brain/physiopathology ; Conditioning, Operant/*physiology ; Electroencephalography ; Epilepsy/physiopathology/*therapy ; Humans
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  • 155
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    Induction of luteolysis in the human with a long-acting analog of luteinizing hormone-releasing factor (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-27
    Description: Subcutaneous injection of 50 micrograms of a long-acting analog of luteinizing hormone-releasing factor on each of two successive days during mid-luteal phase in normally cycling women induced a short luteal phase and premature menstruation. These events were associated with luteolysis, as evidenced by the consistent and parallel premature decline of progesterone and estradiol levels compared with those in control cycles. This finding may prove to be useful in the prevention or interception of implantation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Casper, R F -- Yen, S S -- New York, N.Y. -- Science. 1979 Jul 27;205(4404):408-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/377491" target="_blank"〉PubMed〈/a〉
    Keywords: Corpus Luteum/drug effects/*physiology ; Estradiol/blood ; Female ; Follicle Stimulating Hormone/blood ; Gonadotropin-Releasing Hormone/*analogs & derivatives ; Humans ; Luteal Phase/*drug effects ; Luteinizing Hormone/blood ; Menstruation/*drug effects ; Progesterone/blood
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  • 156
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    Selective phospholipid adsorption and atherosclerosis (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: Disaturated (fully saturated) lecithins adsorb onto solid surfaces more readily than lecithins in which one or both fatty acids are unsaturated. If saturated lecithins adsorb to arterial walls as they do to glass and polystyrene surfaces, there may be increased probability of atherosclerosis when the disaturated lecithin content of plasma is elevated. Analyses of lecithins in plasma samples from patients with myocardial infarction, and from patients with premature atherosclerosis but with low concentrations of plasma cholesterol and triglycerides, are consistent with the hypothesis that a high concentration of disaturated lecithin in plasma may be a significant risk factor for atherosclerosis, independent of triglyceride and cholesterol concentrations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gershfeld, N L -- New York, N.Y. -- Science. 1979 May 4;204(4392):506-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/581915" target="_blank"〉PubMed〈/a〉
    Keywords: Adsorption ; Adult ; Aged ; Arteriosclerosis/blood/*etiology ; Coronary Disease/*blood ; Fatty Acids, Unsaturated ; Female ; Humans ; Male ; Middle Aged ; Myocardial Infarction/blood ; *Phosphatidylcholines/blood ; Pulmonary Surfactants/blood ; Structure-Activity Relationship ; Temperature
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  • 157
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    Narcotic analgesia: fentanyl reduces the intensity but not the unpleasantness of painful tooth pulp sensations (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-23
    Description: Forty subjects rated the magnitude of painful electrical stimulation of tooth pulp before and after the intravenous administration of either fentanyl, a short-acting narcotic, or a saline placebo. The responses were choices of verbal descriptors from randomized lists of either sensory intensity (that is, weak, mild, intense) or unpleasantness (annoying, unpleasant, distressing) descriptors. The fentanyl significantly reduced the sensory intensity without reducing the unpleasantness of the tooth pulp stimuli, indicating that the mechanisms of narcotic analgesia may include a significant attenuation in pain sensation in addition to effects on pain reaction. These results stress the importance of using multiple measures of pain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gracely, R H -- Dubner, R -- McGrath, P A -- New York, N.Y. -- Science. 1979 Mar 23;203(4386):1261-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424753" target="_blank"〉PubMed〈/a〉
    Keywords: Dental Pulp/innervation ; Double-Blind Method ; Electric Stimulation ; Fentanyl/*pharmacology ; Humans ; Injections, Intravenous ; Nociceptors/drug effects ; Pain/*physiopathology
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  • 158
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    Prenatal stress reduces fertility and fecundity in female offspring (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: Female rats subjected to prenatal stress later experienced fewer conceptions, more spontaneous abortions and vaginal hemorrhaging, longer pregnancies, and fewer viable young than nonstressed rats. The offspring of the prenatally stressed rats were lighter in weight and less likely to survive the neonatal period. Prenatal stress may influence the balance of adrenal and gonadal hormones during a critical stage of fetal hypothalamic differentiation, thereby producing a variety of reproductive dysfunctions in adulthood.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Herrenkohl, L R -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1097-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/573923" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Disorders of Sex Development/etiology ; Female ; Gestational Age ; Humans ; Infertility, Female/*etiology ; Lighting ; Litter Size ; Maternal Behavior ; Pregnancy ; Rats ; Reproduction ; Stress, Psychological/*complications
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  • 159
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    Long-term choline treatment of memory-impaired elderly patients (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ferris, S H -- Sathananthan, G -- Reisberg, B -- Gershon, S -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):1039-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472728" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Alzheimer Disease/drug therapy ; Dementia/drug therapy ; Humans ; Memory Disorders/*drug therapy ; Parasympathomimetics/*therapeutic use ; Time Factors
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  • 160
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    Phenformin ban (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Finkel, M J -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):242.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432643" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Phenformin/adverse effects/*standards ; United States ; United States Food and Drug Administration
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 161
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    Noncycling tumor cells are sensitive targets for the antiproliferative activity of human interferon (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: Resting Burkitt's lymphoma cells (Daudi) in culture are more sensitive targets for the antiproliferative activity of purified human fibroblast interferon than cells that are rapidly multiplying. Thus, interferon may be of significant clinical value in neoplasms involving stem cells and, after chemotherapy, in suppressing the reemergence of tumors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Horoszewicz, J S -- Leong, S S -- Carter, W A -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1091-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493995" target="_blank"〉PubMed〈/a〉
    Keywords: Burkitt Lymphoma/drug therapy/pathology ; Cell Cycle/drug effects ; Cell Division/*drug effects ; Cell Line ; Cells, Cultured ; Humans ; Interferons/*pharmacology/therapeutic use ; Lymphocytes/drug effects
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 162
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    Social science research ethics (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Horowitz, Irving L -- Garn, Stanley M -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1022.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11643506" target="_blank"〉PubMed〈/a〉
    Keywords: *Behavioral Research ; *Deception ; Humans ; Journalism ; Methods ; *Research ; Research Personnel ; Social Sciences
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 163
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    Low urinary estrogen glucuronides in women at risk for familial breast cancer (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: Daily (12-hour) urine collections taken throughout the menstrual cycle were obtained from 30 young women who by genetic analysis were at risk for familial breast cancer, and from 30 control women carefully matched for age, height, and reproductive history. Steroids in the urine were extracted by glucuronidase hydrolysis, and the primary glucocorticoid, androgen, and estrogen hormones and their metabolites were measured by radioimmunoassay. Highly significant differences were observed only in the case of estrone and estradiol, with the high-risk subjects exhibiting lower values that the controls. This endocrine abnormality in young women at risk for breast cancer may be a potential discriminant for identifying women at risk for the disease in the population at large.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fishman, J -- Fukushima, D K -- O'Connor, J -- Lynch, H T -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1089-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451553" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Age Factors ; Breast Neoplasms/genetics/*urine ; Estradiol/urine ; Estriol/urine ; Estrogens/*urine ; Estrone/urine ; Female ; Humans ; Menopause ; Menstruation ; Parity ; Puberty ; Risk ; Seasons
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 164
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    A systematic assessment of early African hominids (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-26
    Description: A large sample of Pliocene fossil hominid remains has been recovered from the African sites of Hadar in Ethiopia and Laetolil in Tanzania. These collections, dating approximately between 2.9 and 3.8 million years ago, constitute the earliest substantial record of the family Hominidae. This article assesses the phylogenetic relationships of the newly discovered fossil hominids and provides a taxonomy consistent with that assessment. A new taxon, Australopithecus afarensis, has been created to accommodate these Pliocene hominid fossils.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johanson, D C -- White, T D -- New York, N.Y. -- Science. 1979 Jan 26;203(4378):321-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/104384" target="_blank"〉PubMed〈/a〉
    Keywords: Africa, Eastern ; Africa, Southern ; Animals ; Biological Evolution ; Craniology ; Dental Arch ; *Fossils ; Haplorhini/*anatomy & histology/classification ; History, Ancient ; Humans ; *Paleodontology ; *Paleontology ; Phylogeny ; Primates/*anatomy & histology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 165
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    C26 sterol in a human urine (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: A new C26 sterol, 22-trans-27-norcholesta-5,22-dien-3 beta-ol, was found in the urine of a 6-year-old girl, with a clinical diagnosis of congenital adrenal hyperplasia of the salt losing type, accompanied by symptoms of mixed sex anatomy and skin pigmentation. The structure of the sterol was determined by comparison with the synthetic compound. The sterol was also detected in ther serum. This appears to be the first case in which a C26 sterol has occurred in mammalia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ikekawa, N -- Fujimoto, Y -- Isiguro, M -- Suwa, S -- Hirayama, Y -- Mizunuma, H -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1223-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451568" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocortical Hyperfunction/*urine ; Child ; Cholestadienols/blood/*urine ; Female ; Humans ; Norsteroids/blood/urine
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  • 166
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    Sleeping pills and insomnia (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Joseph, H L -- New York, N.Y. -- Science. 1979 Jul 6;205(4401):8, 122.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451583" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Hypnotics and Sedatives/*adverse effects ; Sleep Initiation and Maintenance Disorders/*drug therapy ; *Substance-Related Disorders
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 167
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    Fetal mortality and sex ratio (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lowry, J T -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1428.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505019" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Fetal Death/*epidemiology ; Humans ; Male ; Pregnancy ; *Sex Ratio
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  • 168
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    Monoclonal antibodies defining distinctive human T cell surface antigens (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: Three novel nonoclonal antibodies (designed OKT1, OKT3, and OKT4) were generated against surface determinants of human peripheral T cells. Both OKT1 and OKT3 reacted with all human peripheral T cells and 5 to 10 percent of thymocytes but differed in their reactivities with T cel- lines. By contrast, OKT4 reacted with 55 percent of human peripheral T cells and 80 percent of thymocyted in that they did not react with normal B cells, null cells, monocytes, or granulocytes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kung, P -- Goldstein, G -- Reinherz, E L -- Schlossman, S F -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):347-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/314668" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibody Specificity ; Antigens, Surface/*analysis ; Cells, Cultured/immunology ; Clone Cells/immunology ; Humans ; Leukemia, Experimental/immunology ; Mice ; Plasmacytoma/immunology ; T-Lymphocytes/*immunology
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  • 169
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    Brain peptides: is substance P a transmitter of pain signals? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1979 Aug 31;205(4409):886-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/38502" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*physiology ; Endorphins/physiology ; Ganglia, Spinal/physiology ; History, 20th Century ; Humans ; Nerve Endings/metabolism ; Neurotransmitter Agents/*physiology ; Nociceptors/*physiology ; Pain/*physiopathology ; Spinal Cord/physiology ; Substance P/history/*physiology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 170
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    Interferon (II): Learning about how it works (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1293-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451535" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphate/metabolism ; Animals ; Humans ; Interferons/biosynthesis/metabolism/*pharmacology ; Killer Cells, Natural/immunology ; Macrophages/drug effects/immunology ; Protein Kinases/metabolism ; Receptors, Drug/metabolism ; Viral Proteins/biosynthesis ; Viruses/drug effects
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  • 171
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    Interpreting "imitative" responses in early infancy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Masters, J C -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):215.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451594" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/*physiology ; Humans ; *Infant, Newborn ; Methods ; Movement
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  • 172
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    Interferon (I): on the threshold of clinical application (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1183-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451564" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Interferons/adverse effects/isolation & purification/supply & ; distribution/*therapeutic use ; Neoplasms/*therapy ; Virus Diseases/therapy
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  • 173
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    Somatostatin cell processes as pathways for paracrine secretion (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: Somatostatin is produced by gastrointestinal endocrine cells that have long, nonluminal, cytoplasmic processes. Such processes terminate on other cell types, including gastrin-producing and hydrochloric acid-producing cells, whose functions are profoundly affected by somatostatin. The findings suggest that somatostatin cells control the functions of other cells through local release of the peptide by way of cytoplasmic processes. Also, certain other types of gastrointestinal endocrine cells have similar cytoplasmic prolongations, which may have analogous local (paracrine) regulatory functions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Larsson, L I -- Goltermann, N -- de Magistris, L -- Rehfeld, J F -- Schwartz, T W -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1393-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/382360" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Gastric Juice/*secretion ; Gastrins/secretion ; Humans ; Immunoenzyme Techniques ; Pyloric Antrum/cytology/*metabolism ; Rats ; Somatostatin/*physiology
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  • 174
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    Accumulation of a tetrahydroisoquinoline in phenylketonuria (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-19
    Description: 3',4'-Deoxynorlaudanosolinecarboxylic acid (DNLCA), a tetrahydroisoquinoline derived from dopamine and phenylpyruvic acid, has been detected by computerized mass fragmentography in urine of phenylketonuric children and in urine and brain of rats with experimentally induced hyperphenylalaninemia. Levels of DNLCA in brain of treated animals were more than tenfold higher than controls, and the excess tetrahydroisoquinoline appeared to accumulate in the cerebellum and cortex. DNLCA is a noncompetitive inhibitor of dopamine beta-hydroxylase (inhibition constant, Ki, = 0.42 mM) and is taken up by the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lasala, J M -- Coscia, C J -- New York, N.Y. -- Science. 1979 Jan 19;203(4377):283-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/153583" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Animals ; Brain/metabolism ; Child ; Child, Preschool ; Dopamine beta-Hydroxylase/antagonists & inhibitors/pharmacology ; Fenclonine/blood ; Humans ; Papaverine/*analogs & derivatives ; Phenylalanine/blood ; Phenylketonurias/*metabolism ; Rats ; Tetrahydropapaveroline/analogs & derivatives/*metabolism
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  • 175
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    Sister chromatid exchanges in human lymphocytes after exposure to diagnostic ultrasound (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-21
    Description: The frequency of sister chromatid exchanges increased in freshly isolated human lymphocytes as well as in a continuously growing lymphoblast line by exposure to diagnostic levels of ultrasound for 30 minutes. The results confirm previous findings indicating that ultrasound of diagnostic intensities can affect the DNA of animal cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Liebeskind, D -- Bases, R -- Mendez, F -- Elequin, F -- Koenigsberg, M -- New York, N.Y. -- Science. 1979 Sep 21;205(4412):1273-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472742" target="_blank"〉PubMed〈/a〉
    Keywords: Cells, Cultured ; *Chromatids ; *Crossing Over, Genetic ; Humans ; Lymphocytes ; *Ultrasonics/adverse effects
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  • 176
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    Human muscular dystrophy: elevation of urinary dimethylarginines (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: The amounts of the dimethylarginines NG,NG-dimethylarginine (DMA) and NG,N'G-dimethylarginine (DM'A) excreted in the urine of muscular dystrophic patients were examined and compared with the amounts excreted by normal controls, patients with other types of neuromuscular diseases, and patients with disuse muscle atrophy resulting from traumatic paralysis. The patients with muscular dystrophy excreted high concentrations of DMA and this urine showed high ratios of DMA to DM'A. This finding indicates a relation between protein methylation processes and muscular dystrophy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lou, M F -- New York, N.Y. -- Science. 1979 Feb 16;203(4381):668-70.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760213" target="_blank"〉PubMed〈/a〉
    Keywords: Arginine/*analogs & derivatives/metabolism/urine ; Creatine/urine ; Creatinine/urine ; Humans ; Methylation ; Muscle Proteins/metabolism ; Muscular Dystrophies/metabolism/*urine
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  • 177
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    Retrograde amnesia for old (reactivated) memory: some anomalous characteristics (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: Old memory, when reactivated by cue exposure, was disrupted by mild or deep hypothermia treatments. New memory was impaired only by deep cooling. Moreover, old but not new learning showed spontaneous recovery. Old reactivated memory may be qualitatively different from newly acquired memory.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mactutus, C F -- Riccio, D C -- Ferek, J M -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1319-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/572083" target="_blank"〉PubMed〈/a〉
    Keywords: Aging ; Amnesia/*physiopathology ; Amnesia, Retrograde/*physiopathology ; Animals ; Avoidance Learning/physiology ; Humans ; Hypothermia/*physiopathology ; Male ; Memory/*physiology ; Rats ; Time Factors
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  • 178
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    Hormones and their effects in the aging body (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1979 Nov 16;206(4420):805-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/227057" target="_blank"〉PubMed〈/a〉
    Keywords: *Aging ; Breast Neoplasms/etiology ; Estrogens/physiology ; Female ; Hormones/*physiology ; Humans ; Male ; Menopause ; Osteoporosis/etiology ; Progesterone/physiology ; Receptors, Cell Surface/physiology ; Testosterone/physiology ; Uterine Neoplasms/etiology
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  • 179
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    Thyroid hormone action at the cellular level (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-09
    Description: A large body of circumstantial evidence suggests that the basic unit of thyroid hormone action is the triiodothyronine nuclear receptor complex. This complex stimulates the formation, directly or indirectly, of a diversity of messenger RNA (mRNA) sequences. A generalized increase in mRNA as well as a disproportionate increase in a limited number of RNA sequences have been demonstrated. Regulation of thyroid hormone effects may be carried out largely at a local cellular level. Highly selective alterations in sensitivity to the triiodothyronine nuclear receptor complex may occur at specific target genes. Metabolic factors and hormones participate in such regulation. In a given tissue, alterations in the total number of receptor sites has not been shown to be useful as an index of thyroid hormone response, and local modulation of the response to the triiodothyronine receptor complex by a variety of factors other than triiodothyronine may be carried out at a postreceptor level.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Oppenheimer, J H -- New York, N.Y. -- Science. 1979 Mar 9;203(4384):971-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/218285" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Nucleus/metabolism ; Cytoplasm/metabolism ; Energy Metabolism ; Humans ; Kinetics ; Lipid Metabolism ; Protein Binding ; RNA, Messenger/biosynthesis ; Receptors, Cell Surface/*physiology ; Thyroid Gland/physiology ; Thyroxine/metabolism ; Tissue Distribution ; Triiodothyronine/*physiology
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  • 180
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    Stress and coping factors influence tumor growth (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-03
    Description: Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated as a result of various stress regimens. A single session of inescapable shock resulted in earlier tumor appearance, exaggeration of tumor size, and decreased survival time in recipient animals. Escapable shock had no such effects. The effects of the inescapable shock were mitigated if mice received long-term shock treatment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sklar, L S -- Anisman, H -- New York, N.Y. -- Science. 1979 Aug 3;205(4405):513-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/109924" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Electroshock ; Humans ; Male ; Mast-Cell Sarcoma/complications/*physiopathology ; Mice ; Neoplasms, Experimental/complications/physiopathology ; Stress, Psychological/complications/*physiopathology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 181
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    Sleeping pills and insomnia (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, J R -- New York, N.Y. -- Science. 1979 Jul 6;205(4401):7-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451581" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Hypnotics and Sedatives/*adverse effects/standards ; Sleep Initiation and Maintenance Disorders/*drug therapy
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 182
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    Inhibition of gonadotropin by delta9-tetrahydrocannabinol:mediation by steroid receptors? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: Competition assays for estradiol receptors in cytosol preparations of uteri from rhesus monkeys and humans showed that delta9-tetrahydrocannabinol (THC) does not compete with estradiol for intracellular estrogen recptors. Although isotopically labeled THC bound to macromolecules in uterine cytosol from the rhesus monkey, the binding was not displaced by unlabeled THC, diethylstilbestrol, estradiol, progesterone, cortisol, or 5 alpha-dihydrostestosterone. Scatchard analyses indicated that high-affinity saturable binding of THC to cytosol did not occur. Thus the inhibitory effect of THC on gonadotropin and steroid secretion in primates is not mediated by the interaction of THC with intracellular steroid hormone receptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R G -- Besch, N F -- Besch, P K -- Smith, C G -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):325-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/107589" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding, Competitive ; Cytosol/metabolism ; Diethylstilbestrol/metabolism ; Dronabinol/*pharmacology ; Estradiol/metabolism ; Female ; Haplorhini ; Humans ; Receptors, Estrogen/*drug effects/metabolism ; Steroids/metabolism ; Uterus/*metabolism
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 183
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    Toxic substances: EPA and OSHA are reluctant regulators (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):28-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758675" target="_blank"〉PubMed〈/a〉
    Keywords: Cadmium/standards/toxicity ; Carcinogens/standards ; *Environmental Health ; *Government Agencies ; Humans ; Occupational Medicine/*standards ; Pesticides/toxicity ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 184
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    Study finds sleeping pills overprescribed (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):287-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219479" target="_blank"〉PubMed〈/a〉
    Keywords: Barbiturates/adverse effects/pharmacology ; Benzodiazepines/adverse effects/metabolism ; Humans ; Hypnotics and Sedatives/*adverse effects ; Metabolic Clearance Rate ; Sleep, REM/drug effects ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 185
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    Federal government faces painful decision on Darvon (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Mar 2;203(4383):857-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/419410" target="_blank"〉PubMed〈/a〉
    Keywords: Dextropropoxyphene/*adverse effects/therapeutic use ; Humans ; *Legislation, Drug ; Substance-Related Disorders ; United States ; United States Dept. of Health and Human Services
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  • 186
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    Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: In order to determine if brain tissue grafts can provide functional input to recipient central nervous system tissue, fetal rat dopamine-containg neurons were implanted adjacent to the caudate nucleus of adult recipients whose endogenous dopaminergic input had been destroyed. The grafts showed good survival and axonal outgrowth. Motor abnormalities, which had been induced by the destruction of the endogenous dopaminergic input to the caudate, were significantly reduced after grafting of the fetal brain tissue. These data suggest that such implants may be potentially useful in reversing deficits after circumscribed destruction of brain tissue.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perlow, M J -- Freed, W J -- Hoffer, B J -- Seiger, A -- Olson, L -- Wyatt, R J -- New York, N.Y. -- Science. 1979 May 11;204(4393):643-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/571147" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Corpus Striatum/physiology ; Disease Models, Animal ; Graft Survival ; Humans ; Hydroxydopamines/toxicity ; Male ; Movement Disorders/physiopathology ; Parkinson Disease/therapy ; Rats ; Stereotyped Behavior/physiology ; Substantia Nigra/embryology/physiology/*transplantation ; Transplantation, Homologous
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  • 187
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    Darvon safety (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pettinga, C W -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432625" target="_blank"〉PubMed〈/a〉
    Keywords: Dextropropoxyphene/adverse effects/*standards ; Drug Industry ; Drug Labeling ; Humans ; Substance-Related Disorders
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 188
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    Retinoblastoma with 13q- chromosomal deletion associated with maternal paracentric inversion of 13q (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-09
    Description: A girl with sporadic unilateral retinoblastoma and mental retardation has an interstitial deletion in the long arm of chromosome 13. Her mother has a paracentric inversion of one chromosome 13; the deleted chromosome 13 in the daughter is derived from the mother's normal chromosome 13.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sparkes, R S -- Muller, H -- Klisak, I -- New York, N.Y. -- Science. 1979 Mar 9;203(4384):1027-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424728" target="_blank"〉PubMed〈/a〉
    Keywords: Child ; Chromosome Aberrations/*genetics ; *Chromosome Deletion ; Chromosome Disorders ; *Chromosome Inversion ; *Chromosomes, Human, 13-15 ; Eye Neoplasms/*genetics ; Female ; Humans ; Models, Biological ; Retinoblastoma/*genetics
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  • 189
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    Morphine-naloxone interactions: a role for nonspecific morphine excitatory effects in withdrawal (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: The opiate antagonist naloxone precipitates withdrawal when given either 15 minutes after or 1 minute before a single injection of morphine in drug-naive mice. We propose that withdrawal signs arise from a synergistic mixture of excitatory influences that are direct (agonistic action on nonspecific opiate receptors) and indirect (sensory and affective disorders, stress, hormonal and neurotransmitter dysfunction, and so forth). The predominant effects during precipitated withdrawal are assumed to be direct, whereas during abstinence in tolerant animals they are indirect.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stevens, D R -- Klemm, W R -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1379-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/224462" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/physiology ; Dose-Response Relationship, Drug ; Drug Interactions ; Drug Tolerance ; Female ; Humans ; Mice ; Morphine/*pharmacology ; Naloxone/*pharmacology ; Receptors, Opioid/*drug effects ; Stereotyped Behavior/physiology ; Substance Withdrawal Syndrome/*physiopathology
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  • 190
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    Radiation from tritiated thymidine perturbs the cell cycle progression of stimulated lymphocytes (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-09
    Description: Tritiated thymidine was found to affect the cell cycle progression of phytohemagglutinin-stimulated human lymphocytes. By means of flow cytometry a statistically significant increase in the G2 and M phases of the cell cycle was observed in cultures with low concentrations of tritiated thymidine added 18 hours before the cultures were harvested.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pollack, A -- Bagwell, C B -- Irvin, G L 3rd -- New York, N.Y. -- Science. 1979 Mar 9;203(4384):1025-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424727" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Cycle/drug effects/*radiation effects ; Dose-Response Relationship, Radiation ; Humans ; Lymphocyte Activation/*radiation effects ; Lymphocytes/*radiation effects ; Mitosis/radiation effects ; Phytohemagglutinins/pharmacology ; Thymidine/pharmacology ; Time Factors ; *Tritium
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  • 191
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    Simultaneous production of Q and R bands after staining with chromomycin A3 or olivomycin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: Human and mouse chromosomes, stained with either chromomycin A3 or olivomycin, which bind preferentially to G - C-rich DNA (where G is guanosine and C is cytosine), exhibit a Q or a reverse banding pattern, depending on the wavelength used for excitation. The two complementary banding patterns can be observed in the same metaphase simply by changing the combination of excitation filters. These data suggest, therefore, that in addition to base composition, other factors are involved in the production of chromosome banding by chromomycin A3 and olivomycin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prantera, G -- Bonaccorsi, S -- Pimpinelli, S -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):79-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/86207" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cells, Cultured ; Centromere/ultrastructure ; *Chromomycins ; Chromosomes/*ultrastructure ; *Dna ; Fluorescent Dyes ; Humans ; Mice ; *Olivomycins ; Staining and Labeling
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  • 192
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    Human macrophage migration inhibition factor: evidence for subunit structure (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: Macrophage migration inhibition factor (MIF) derived from human lymphoid cell lines was found to lose biologic activity on dialysis. Although activity was not recovered in the dialyzate, mixing experiments demonstrated that the components in the retentate and dialyzate could reassociate to restore activity. The fragment of larger molecular weight (less than 10,000) could inhibit the activity of intact MIF, whereas the smaller molecular weight fragment (5,000 to 10,000) could not. These findings suggest that human MIF is composed of at least two noncovalently linked subunits. In analogy to the situation for certain bacterial toxins, one of these may represent an attachment piece for a target cell membrane receptor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Possanza, G -- Cohen, M C -- Yoshida, T -- Cohen, S -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):300-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/377487" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Line ; Dialysis ; Humans ; In Vitro Techniques ; Lymphocytes/physiology ; Macromolecular Substances ; *Macrophage Migration-Inhibitory Factors ; Molecular Weight
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  • 193
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    Phenylethylamine in paranoid chronic schizophrenia (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-26
    Description: Phenylethylamine (PEA) is an endogenous amine that is structurally and pharmacologically related to amphetamine. Urinary PEA excretion is significantly higher in paranoid chronic schizophrenics than in nonparanoid chronic schizophrenics and normal controls. Diet, hospitalization, and medication do not account for differences in PEA concentrations. These findings offer some indication that PEA may be an endogenous amphetamine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Potkin, S G -- Karoum, F -- Chuang, L W -- Cannon-Spoor, H E -- Phillips, I -- Wyatt, R J -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):470-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504988" target="_blank"〉PubMed〈/a〉
    Keywords: Chronic Disease ; Diet ; Hospitalization ; Humans ; Phenethylamines/*urine ; Schizophrenia/urine ; Schizophrenia, Paranoid/*urine
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  • 194
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    Multiple sclerosis: presence of lymphatic capillaries and lymphoid tissue in the brain and spinal cord (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-16
    Description: Thin-walled channels resembling lymphatic capillaries and containing lymphocytes were observed in perivascular spaces throughout the central nervous system of patients with various neurological disorders. This suggests that immunological surveillance in the central nervous system may normally involve lymphocyte circulation through the perivascular compartment. In some old multiple sclerosis plaques, perivascular lymphoid tissue was found which was organized in a manner similar to the antibody-producing medullary region of lymph nodes. This may indicate continuous processing of the putative multiple sclerosis antigen in such lesions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prineas, J W -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1123-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424741" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/immunology/*pathology ; Humans ; Lymphatic System/*pathology ; Lymphoid Tissue/*pathology ; Multiple Sclerosis/*immunology/pathology ; Plasma Cells/pathology ; Spinal Cord/immunology/*pathology
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  • 195
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    Diabetes drugs: clinical trial (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prout, T E -- Knatterud, G L -- Meinert, C G -- New York, N.Y. -- Science. 1979 Apr 27;204(4391):362-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/375390" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Trials as Topic ; Control Groups ; Diabetes Mellitus/*drug therapy ; Drug Evaluation/methods ; Drug Therapy ; Humans ; Hypoglycemic Agents/*toxicity ; Risk Assessment ; United States ; United States Food and Drug Administration
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  • 196
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    Estimating fatness (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Reeves, J -- New York, N.Y. -- Science. 1979 May 25;204(4395):881.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441744" target="_blank"〉PubMed〈/a〉
    Keywords: *Adipose Tissue ; Adolescent ; Anthropometry/*methods ; Body Height ; Body Water/analysis ; *Body Weight ; Female ; Humans ; Menarche
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  • 197
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    Visually guided locomotion: psychophysical evidence for a neural mechanism sensitive to flow patterns (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: Inspecting a radial flow pattern depressed visual sensitivity to changes in the size of a small test square, but only when the square was located near the focus of the flow pattern. The result suggests that precise visual judgments of one's direction of forward motion with respect to the outside world may be mediated by an already known neural organization sensitive to changes in the size of small objects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Regan, D -- Beverley, K I -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):311-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451604" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; *Locomotion ; Sensory Thresholds ; *Visual Perception
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  • 198
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    Reading without a fovea (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-26
    Description: A visual mask moving in synchrony with the eye obliterated foveal vision during reading under certain conditions. When foveal vision was masked, reading became difficult. In another condition, a window of readable text moved in synchrony with the eye, and parafoveal vision was masked on each fixation. The results point out the importance of foveal and parafoveal vision in reading.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rayner, K -- Bertera, J H -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):468-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504987" target="_blank"〉PubMed〈/a〉
    Keywords: Eye Movements ; Fovea Centralis/*physiology ; Humans ; Macula Lutea/*physiology ; *Reading ; *Vision, Ocular ; Visual Fields
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  • 199
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    Chemical carcinogens: estimating the risk (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Reitz, R H -- Quast, J F -- Watanabe, P G -- Gehring, P J -- New York, N.Y. -- Science. 1979 Sep 21;205(4412):1206-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472737" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biotransformation ; *Carcinogens ; Humans ; Risk ; Species Specificity ; Vinyl Chloride/metabolism
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  • 200
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    Tumor surveillance: how tumors may resist macrophage-mediated host defense (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-12
    Description: Both normal human serum and supernatant from explanted malignant tumors contained a heat-stable low-molecular-weight factor that inhibited monocyte activation in vitro. In contrast, serum from individuals with solid tumors enhanced monocyte activation. It is suggested that the systemic activation of monocytes that occurs in malignant disease may be an appropriate host response but that successful tumors may continue to grow because they subvert the normal physiological signal for inhibition of macrophage activation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rhodes, J -- Bishop, M -- Benfield, J -- New York, N.Y. -- Science. 1979 Jan 12;203(4376):179-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758686" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Carcinoma/*immunology ; Carcinoma, Squamous Cell/immunology ; Chemotaxis ; Colonic Neoplasms/*immunology ; Humans ; Immunity, Cellular ; Immunoglobulin Fc Fragments ; Lung Neoplasms/*immunology ; Macrophages/*immunology ; Monocytes/*immunology ; Rosette Formation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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