Publication Date:
1988-09-30
Description:
Restriction of maternal dietary sodium on or before embryonic day 8 reduced taste responses of the chorda tympani nerve to sodium chloride in the offspring. The response attenuation was substantial; responses to sodium chloride in the offspring of deprived rats were approximately 40 percent of those in control animals. Instituting the low sodium diet at embryonic day 10 or later did not produce functional changes. Thus, a sensitive period for the gustatory system exists, and the abrupt transition from maximal environmental susceptibility to no susceptibility occurs during a 2-day prenatal period. Moreover, events important in determining the developmental fate of taste membrane components occur before the initial formation of taste buds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hill, D L -- Przekop, P R Jr -- NS01215/NS/NINDS NIH HHS/ -- NS24741/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1988 Sep 30;241(4874):1826-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychology, University of Virginia, Charlottesville 22903.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3175625" target="_blank"〉PubMed〈/a〉
Keywords:
Amiloride/pharmacology
;
Animals
;
Neurons/physiology
;
Rats
;
Sensory Receptor Cells/*physiology
;
Sodium/deficiency/*physiology
;
Taste/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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