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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Human physiology. ; Neurology . ; Life sciences. ; Physiology. ; Neuroscience. ; Human Physiology. ; Neurology. ; Life Sciences. ; Animal Physiology. ; Life Sciences.
    Description / Table of Contents: Part I: HISTORY -- Chapter 1: Transmissible Spongiform Encephalopathy: from its beginnings to Daniel Carleton Gajdusek -- Part II: GENERAL ASPECTS OF PRIONS -- Chapter 2: The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein -- Chapter 3: Mammalian Prion Structures -- Chapter 4: Insoluble Cellular Prion Protein and Other Neurodegeneration-related Misfolded Protein Aggregates in the Brain of Asymptomatic Individuals -- Part III: CONVERSION AND STRAIN OF PRIONS -- Chapter 5: Prion Conversion and Deformed Templating -- Chapter 6: Prion Strain Interference -- Chapter 7: Molecular Mechanisms Encoding Strains of Prions and Prion-Like Misfolded Proteins -- Chapter 8: Cofactor Involvement in Prion Propagation -- Chapter 9: Prion Protein Conversion and Lipids -- Part IV: ENVIRONMENT AND TRANSMISSION OF PRIONS -- Chapter 10: Prions in the Environment -- Chapter 11: Environmentally Acquired Transmissible Spongiform Encephalopathy -- Chapter 12: Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion -- Chapter 13: Species Barriers in Prion Disease -- Part V: MODELLING OF PRIONS -- Chapter 14: Modeling the Cell Biology of Prions -- Chapter 15: Transgenic Mice Modelling in Prion Diseases -- Chapter 16: Stem Cell Models in Prion Research -- Chapter 17: Drosophila Models of Prion Diseases -- Part VI: HUMAN PRION DISEASES AND OTHER PATHOLOGIES -- Chapter 18: Human Sporadic Prion Diseases -- Chapter 19 Genetic Creutzfeldt-Jakob and Gerstmann-Sträussler-Scheinker Diseases -- Chapter 20: Glycoform-selective Prions in Sporadic and Inherited Variably Protease-sensitive Prionopathies -- Chapter 21: The Spectrum of Tau Pathology in Human Prion Disease -- Chapter 22: Prion Protein Complex with mGluR5 Mediates Amyloid-ß Synaptic Loss in Alzheimer’s Disease -- Chapter 23: Prion and Cancers -- Chapter 24: Protective Role of Cellular Prion Protein in Tissue Ischemic/Reperfusion Injury -- Part VII: ANIMAL PRION DISEASES -- Chapter 25: Bovine Spongiform Encephalopathy -- Chapter 26: Classical and Atypical Scrapie in Sheep and Goats -- Chapter 27: Research models for studying chronic wasting disease -- Part VIII: YEAST PRIONS -- Chapter 28: Introduction to Yeast and Fungal Prions -- Chapter 29: Yeast Prions Are Folded, In-Register Parallel Amyloids Subject to Multiple Anti-prion Systems -- Part IX: DIAGNOSIS AND HUMAN PRION SURVEILLANCE -- Chapter 30: Real-time quaking-induced conversion (QuIC) assays for the detection and diagnosis of human prion diseases -- Chapter 31: Protein Misfolding Cyclic Amplification -- Chapter 32: Skin Misfolded Proteins as Biomarkers for Diagnosis of Prion and Prion-like Diseases -- Chapter 33: Diagnosis of Prion Disease: Conventional Approaches -- Chapter 34: Human Prion Disease Surveillance -- Part X: TREATMENT -- Chapter 35: Overview on Treatment of Prion Diseases and Decontamination of Prions -- Chapter 36: Gene Therapy Strategies for Prophylactic and Therapeutic Treatments of Human Prion Diseases -- Chapter 37: Immunomodulation.
    Abstract: Transmissible spongiform encephalopathies (TSE), now known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains the most authoritative views about the past, present, and future of prions and prion diseases covering fresh perspectives on important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.
    Type of Medium: Online Resource
    Pages: XII, 793 p. 81 illus., 62 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031205651
    DDC: 612.8
    Language: English
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  • 2
    Keywords: Neurosciences. ; Pain medicine. ; Neurology . ; Anesthesiology. ; Neuroscience. ; Pain Medicine. ; Neurology. ; Anesthesiology.
    Description / Table of Contents: Introduction to Acute, Chronic, and Episodic Pain -- Inflammation and Pain -- Animal Models of Pain and Anti-inflammatory Treatments -- Inflammatory Mediators, Nociceptors, and Their Interactions in Pain -- Immune and Glial Cells in Pain and Their Interactions with Nociceptive Neurons -- Sex Differences in Neuroimmune Interactions and Pain -- Neuroimmune Interactions in Itch -- Toll-like Receptors in Pain and Itch -- Immunotherapy and Pain -- Cell Therapy and Regenerative Pain Medicine - Preclinical Studies -- Cell-based Therapies in Pain Management -- Platelet-Rich Plasma and Autologous Conditioned Serum: Non-Cellular Biologic Therapies for Neuroimmune Modulation and the Treatment of Arthritis Pain -- Exercise and Diet in the Control of Inflammation and Pain -- Mechanism-Based Pain Therapies -- Neuromodulation in Pain Management -- What Patients Need to Know about Pain Therapy?.
    Abstract: As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be the turning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.
    Type of Medium: Online Resource
    Pages: X, 364 p. 45 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031292316
    DDC: 612.8
    Language: English
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  • 3
    Keywords: Neurosciences. ; Cognitive neuroscience. ; Psychobiology. ; Human behavior. ; Sociology. ; Neuroscience. ; Cognitive Neuroscience. ; Behavioral Neuroscience. ; Sociology.
    Description / Table of Contents: Molecular imaging of the human emotion circuit -- The neurocognitive mechanisms of unconscious emotional responses -- Social and Affective Neuroscience of Embodiment -- The neuroscience of beauty -- Mirror Neurons … in action: ERPs and neuroimaging evidence -- Sex differences in social cognition -- Development of morality and emotional processing -- Trust in Social Interaction: From Dyads to Civilizations -- The time has come to be mindwanderful: Mind wandering and the intuitive psychology mode -- Social Cognition development and socio affective dysfunction in childhood and adolescence -- Clinical neuroscience meets second-person neuropsychiatry -- EEG and ERPs in the study of Language and Social Knowledge -- fMRI and fNIRS methods for social brain studies: hyperscanning possibilities -- Modulating the Social and Affective Brain with transcranial stimulation techniques -- What our eyes can tell us about our social and affective brain? -- Facial EMG – Investigating the interplay of facial muscles and emotions.
    Abstract: This Open Access book presents the current state of the art knowledge on social and affective neuroscience based on empirical findings. This volume is divided into several sections first guiding the reader through important theoretical topics within affective neuroscience, social neuroscience and moral emotions, and clinical neuroscience. Each chapter addresses everyday social interactions and various aspects of social interactions from a different angle taking the reader on a diverse journey. The last section of the book is of methodological nature. Basic information is presented for the reader to learn about common methodologies used in neuroscience alongside advanced input to deepen the understanding and usability of these methods in social and affective neuroscience for more experienced readers.
    Type of Medium: Online Resource
    Pages: XXXIII, 302 p. 55 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031086519
    DDC: 612.8
    Language: English
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  • 4
    Keywords: Neurosciences. ; Neurology . ; Pharmacology. ; Neuroscience. ; Neurology. ; Pharmacology.
    Description / Table of Contents: Chapter 1: Why study Drug Resistant Epilepsy? -- Chapter 2: Pharmacoresistance in Epilepsy -- Chapter 3: Experimental models for the study of drug-resistant epilepsy -- Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy -- Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy -- Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level? -- Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy -- Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy -- Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy -- Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy -- Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP -- Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance -- Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance -- Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration -- Chapter 15: Application of proteomics in the study of molecular markers in epilepsy -- Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies -- Chapter 17: Genes involved in pharmacoresistant epilepsy -- Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders -- Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery -- Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses -- Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility -- Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy -- Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy -- Chapter 24: Vagus Nerve Stimulation for Intractable Seizures -- Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy -- Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.
    Abstract: This new edition of Pharmacoresistance in Epilepsy addresses all issues relating to drug-resistance in epilepsy, including studies in patients as well in experimental models and presents the basis for an understanding of recent developments in the pathogenesis and treatment of this condition. Important issues associated with drug-resistant epilepsy are reviewed and updated, such as abnormalities in inhibitory mechanisms, neurotoxicity and changes the immune system associated with this disorder, and the development of drug-resistance as consequence of chronic exposure to antiseizure-medications. Considering that a major obstacle is that epilepsy associated with drug-resistance cannot be controlled with the traditional antiseizure medications, specific chapters describe therapeutic strategies to prevent or reduce the progression of the disease with complementary medical therapies, such as transcranial focal stimulation to promote neuroprotection. Pharmacoresistance in Epilepsy is a valuable resource for anyone working in the field, whether studying epilepsy in the lab or treating it in an office.
    Type of Medium: Online Resource
    Pages: XV, 596 p. 84 illus., 79 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031365263
    DDC: 612.8
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurology . ; Developmental neurobiology. ; Neuroscience. ; Neurology. ; Development of the Nervous System.
    Description / Table of Contents: The development of the cerebellum: from the beginnings -- Part I: Responsibilities and liabilities -- Chapter2. The embryology and anatomy of the cerebellum -- Chapter 3. Cellular and genetic programs underlying cerebellum development -- Chapter 4. Early Purkinje Cell Development and the Origins of Cerebellar Patterning. - Chapter 5. Development of the Fish Cerebellum. -Chapter 6. Cerebellar developmental disorders and cerebellar nuclei -- Chapter 7. Motor circuit abnormalities during cerebellar development -- Chapter8. Developmental disorders of the cerebellum and neurotrophic factors -- Chapter9. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development -- Chapter10. The ubiquitin proteasome system and cerebellar developmental disease -- Chapter11. Epigenetics and Cerebellar Neurodevelopmental Disorders -- Chapter12.. Hormonal regulation of cerebellar development and its disorders -- Chapter13. Infections of the Cerebellum -- Chapter14. Neuroimmune mechanisms of cerebellar development and its developmental disorders -- Chapter15. Teratogenic influences on cerebellar development -- Chapter16. Primary pediatric brain tumors of the posterior fossa -- Chapter17. Primary pediatric brain tumors of the posterior fossa -- Chapter18. Can cerebellar neurodevelopmental disorders affect behavioral disorders or vice versa -- Chapter19. Neurodevelopmental disorders of the cerebellum: autism spectrum disorder -- Chapter20. Congenital cerebellar disease -- Chapter21. Clinical features, assessment, and management of patients with developmental and other cerebellar disorders -- Chapter22. Epidemiology of cerebellar disorders -- Chapter23. Cerebellar transplantation: a potential model to study repair and development of neurons and circuits in the cerebellum. - Chapter 24. Non-coding RNAs and cerebellar development. - Chapter 25. Defining the Cerebellar Cytoarchitecture Using MRI. .
    Abstract: This updated reference covers diverse aspects of cerebellar development from a full range of viewpoints, including the epidemiology of cerebellar genetic disorders, developmental anatomy, cell biology, genetics, epigenetics, infectious diseases, and mechanisms involved in the regulation of cell fate, while also focusing on information that is relevant to clinicians caring for patients with cerebellar disorders. The chapters are written by experts in the field of cerebellar development, and the chapters cover diseases related to the cerebellum, along with their epidemiology, clinical features, assessment, and management. In addition to updating the content to cover the significant developments in the field since the first edition, the second edition will include new chapters on Non-Coding RNAs and Cerebellar Development, Development of the Fish Cerebellum, the Role of nNOS/NO on Cerebellar Development in Health and Disease, and rehabilitation in cerebellar ataxia. The effect of the COVID-19 on the cerebellum has been included in related chapters. Development of the Cerebellum from Molecular Aspects to Diseases, 2nd edition, is designed to be valuable reference for both neuroscientists and clinicians.
    Type of Medium: Online Resource
    Pages: IX, 639 p. 116 illus., 88 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031231049
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry.
    Description / Table of Contents: 1.How Immune-inflammatory processes link neurodegenerative and psychiatric disorders -- 2.Gut-Microbiota-Brain Axis: pathophysiological mechanism in neuropsychiatric disorders -- 3.Microbiome- induced autoimmunity and novel therapeutic intervention -- 4.The key role of microlia and circulating monocytes in etipathology neuropsychiatric disorders -- 5.Neuro-immuno-epigenetics of prenatal psychological stress -- 6.C-reactive protein (CRP): a potent inflammation biomarker in psychiatric disorders -- 7.Neuroinflammation, neurognesis and neuroprotection in schizophrenia -- 8.Autoimmue psycosis: concept, clinical manifestation and management -- 9.Stress, autonomic nervous system and kynurenine pathway in major depression -- 10.Brain-gut-microbiome axis in major depression : novel therapeutic approach -- 11.Glial-Neuronal Interaction in Synapses: A Possible Mechanism of the Pathophysiology of Bipolar Disorder -- 12.Neuroimmaging of inflammation in depression and anxiety disorders -- 13.Neuroinflammation and immune-kynureinine pathway in anxiety disorders -- 14.Inflammatory-mediated responses in development of neurogeneartive diseases -- 15.The connection between gut-brain axis and PTSD -- 16.Eating disorders : Gut microbiota-immune-brain interactions -- 17.Sleep-immune crosstalk and sleep disorders -- 18.Obsessive-compulsive disorder: immuno-inflammatory disorder? -- 19.Cytokine, neuroinflammation and neurodeneration in Alzheimer’s disease -- 20.Molecular imaging of neuroinflammation in Alzheimer's disease and MCI -- 21.The role of N-Methyl-D-Aspartate Receptor Neurotransmission and mictobiota in Alzheimer’s disease -- 22.Neuroglial activation and neuroinflammation in the brain of patients with autism -- 23.Suicide and inflammation -- 24.Anti-inflammatory effect of Traditional Chinese Medicine on the concept of Mind-body interface -- 25.Anti-inflammatory therapy as a promising target in neupsychiatric disorders.
    Abstract: This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.
    Type of Medium: Online Resource
    Pages: XVII, 554 p. 28 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811973765
    Series Statement: Advances in Experimental Medicine and Biology, 1411
    DDC: 612.8
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurophysiology. ; Gastroenterology. ; Neuroscience. ; Neurophysiology. ; Gastroenterology.
    Description / Table of Contents: Tools for optogenetic probing of nociceptive pathways; Monitoring activity -- An open science model to accelerate the generation, implementation and distribution of optogenetics and viral tools -- Vagal neuroinflammation accompanying respiratory viral infection: An overview of mechanisms and possible clinical significance -- Stress-induced Visceral Analgesia: Concept and Pathways -- Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders -- EPIGENETIC REGULATION OF STRESS-INDUCED VISCERAL PAIN -- The biomechanics and mechanotransduction in visceral nociception -- VISCERAL NOCICEPTION IN GASTROINTESTINAL DISEASE -- Epithelial-Neuronal Communication in Visceral Pain -- Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome -- A fentanyl analogue that activates u-opioid receptors in acidified tissues inhibits colitis pain without opioid side effects -- Signalling in the Gut -- Translating colonic sensory afferent peripheral mechanosensitivity into the spinal cord dorsal horn -- Translating colonic afferent peripheral sensitivity into the spinal cord dorsal horn -- Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain -- Pre-clinical Models of Endometriosis -- Spinal afferent innervation of the uterus -- Post-infectious bladder hypersensitivity in the development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
    Abstract: The chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field.
    Type of Medium: Online Resource
    Pages: VIII, 255 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031257025
    DDC: 612.8
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Psychiatry.
    Description / Table of Contents: Part 1: Considering sex and gender in research studies -- Sex and Gender Science -- Best practices in the study of sex? -- Best practices in the study of Gender Differences -- The special case of a lack of sex differences – the naked mole rat? -- Lateralization and -- Part 2: Sex differences in cognitive and mental health across the lifespan -- Depression -- Schizophrenia -- Immune and neurodevelopmental disorders – autism? -- Social Cognition -- Cognition and cognitive ageing -- Part 3: Diseases of the brain and relevance of sex -- Epilepsy -- Stroke -- AD -- Parkinson’s -- Multiple Sclerosis.
    Abstract: Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines of psychology, neuroscience, psychiatry and neurology. Understanding how brain function and resultant behaviors may differ between the sexes impacts upon our knowledge of the pathology and development of treatments for various neurological and psychiatric disorders, particularly those that show significant sex differences in either prevalence and/or manifestation of symptoms. This volume covers three main themes of research into sex differences in basic neurobiology, psychology, preclinical research and clinical research. It begins by exploring our understanding of sex and gender in relation to both animal and human behaviors and discusses the relevance, and importance, of considering sex and gender when conducting research into brain function and behaviors. The second theme focuses on how sex and gender influence mental health and considers the impact of our immune system and the changes that occur with ageing. Finally, the third aspect focuses on examples of neurological disorder which show sex differences in terms of their aetiology and/or symptomology and considers the relevance in the development of treatment for these disorders including dementia, stroke and multiple sclerosis. This volume is of considerable interest to mental health and neurology professionals, including psychiatrists, neurologists, nurses, allied health clinicians and pharmacists. It is also helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology.
    Type of Medium: Online Resource
    Pages: X, 373 p. 70 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031267239
    Series Statement: Current Topics in Behavioral Neurosciences, 62
    DDC: 612.8
    Language: English
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  • 9
    Keywords: Neurosciences. ; Neurology . ; Pharmaceutical chemistry. ; Cognitive neuroscience. ; Neuroscience. ; Neurology. ; Pharmaceutics. ; Cognitive Neuroscience.
    Description / Table of Contents: Part I: Basic Science of Cerebellum and Ataxias -- Functional anatomy of the cerebellum -- Cerebellar physiology -- Cerebellar biochemistry/pharmacology -- Genetics of dominant ataxias -- Autosomal and X-linked degenerative ataxias: from genetics to promising therapeutics -- Seeking therapies for Spinocerebellar Ataxia: from gene silencing to systems-based approaches -- Ion Channel Genes and Ataxia -- Part II: Biomarkers and tools of trials -- How to Design a Therapeutic Trial in SCAs -- Therapy development for spinocerebellar ataxia: Rating Scales and Biomarkers -- Clinical rating scales for ataxia -- Scale for Ocular motor Disorders in Ataxia (SODA): Procedures and Basic Understanding -- Cerebellar learning in the prism adaptation task -- Blood and CSF biomarkers in autosomal dominant cerebellar ataxias -- Part III: Autosomal Dominant Cerebellar Ataxias -- Riluzole in progressive cerebellar ataxias -- ASOs against ATXN2 in preclinical and phase 1 trials -- Antisense oligonucleotide therapy against SCA3 -- Spinocerebellar ataxia type 7: From mechanistic pathways to therapeutic opportunities -- Experimental neurotransplantation for cerebellar ataxias -- Development of mesenchymal stem cells therapy for the treatment of polyglutamine SCA: from bench to bedside -- Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia -- Cerebellar Transcranial Magnetic Stimulation in Cerebellar Ataxias -- Physical therapy in Cerebellar Ataxia -- Part IV: Autosomal Recessive Cerebellar Ataxias -- Recent advances on therapeutic approaches for Friedreich’s Ataxia -- Therapeutic use of interferon gamma in Friedreich ataxia -- Metabolic treatments of cerebellar ataxia -- Clinical Trials in Fragile X-Associated Tremor/Ataxia Syndrome -- Part V: Sporadic Ataxias -- Therapeutic strategies in immune-mediated cerebellar ataxias -- Coenzyme Q10 in MSA -- State of the Art and History of Therapeutics in Ataxias.
    Abstract: Despite the critical importance of the cerebellum in brain functions, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.
    Type of Medium: Online Resource
    Pages: XI, 727 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031243455
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Neurology . ; Neuroscience. ; Neuropsychology. ; Neurology.
    Description / Table of Contents: Chapter 1: Understanding the Mechanisms of Dendritic Arbor Development: Integrated Experimental and Computational Approaches -- Chapter 2: Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive -- Chapter 3: Environmental enrichment and functional plasticity in the hippocampus, an update on the mechanisms involved -- Chapter 4: Translatable Models of Brain and Cognitive Reserve -- Chapter 5: Cognitive Reserve: A Life-Course Perspective -- Chapter 6: Neural Correlates of Brain Reserve: A Neuroimaging Perspective -- Chapter 7: Non-pharmacological Approaches Based on Mind-Body Medicine to Enhancement of Cognitive and Brain Reserve in Humans -- Chapter 8: Roles of Synaptic Plasticity in Functional Recovery After Brain Injury -- Chapter 9: Integrated Methods of Neuromodulation for Guiding Recovery Following Stroke -- Chapter 10: Resilience in Brain Networks After Stroke -- Chapter 11: Epigenetics and brain plasticity: back to function -- Chapter 12: Functional Role of Physical Exercise and Omega-3 Fatty Acids on Depression and Mood Disorders -- Chapter 13: BRAIN RECOVERY IN CHILDHOOD: THE INTERACTION BETWEEN DEVELOPMENTAL PLASTICITY AND REGENERATIVE MECHANISMS -- Chapter 14: Estrogen Neuroprotective Activity After Stroke and Spinal Cord Injury -- Chapter 15: Making Meaning of Acquired Brain Injury: Resources for Functional Recovery -- Chapter 16: An Update on Premorbid Personality Traits and Brain Recovery - Another Aspect of Resilience -- Chapter 17: Psychological Aspects of Recovery After Brain Injury: A Focus on Psychodynamic Factors -- Chapter 18: Artificial Intelligence applications for Traumatic Brain Injury research and clinical management.
    Abstract: The importance of this unique book's approach lies in addressing the impact of neurobiological factors as well as psychological influences on brain recovery following injury. There is growing evidence that emotional, motivational, and cognitive factors along with personality traits play a crucial role in brain plasticity, resilience, and recovery. Topics include synaptic and neuronal plasticity, development of brain reserves, biological markers, environmental factors, emotional resilience, and personality traits. By combining the latest research on neural mechanisms and psychological resilience the authors present a book that will help lead to the development of better treatment strategies for functional recovery from brain damage. The new edition is fully updated throughout and contains completely new chapters on brain recovery in childhood, epigenetic aspects of brain recovery, and artificial intelligence techniques in traumatic brain injury research.
    Type of Medium: Online Resource
    Pages: XXIV, 406 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031249303
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Zoology. ; Neurochemistry. ; Neuroscience. ; Zoology. ; Neurochemistry.
    Description / Table of Contents: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.
    Abstract: This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.
    Type of Medium: Online Resource
    Pages: XII, 501 p. 96 illus., 73 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031123900
    Series Statement: Advances in Neurobiology, 29
    DDC: 612.8
    Language: English
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  • 12
    Keywords: Neurosciences. ; Neurophysiology. ; Developmental neurobiology. ; Neuroscience. ; Neurophysiology. ; Development of the Nervous System.
    Description / Table of Contents: Chapter 1: Introduction: What are dendritic spines? -- Chapter 2: Techniques to render dendritic spines visible in the microscope -- Chapter 3: Electrophysiology of dendritic spines: information processing, dynamic compartmentalization and synaptic plasticity -- Chapter 4: Dendritic spines, synaptogenesis and synaptic pruning for the developmental organization of brain circuits -- Chapter 5: Neurotrophic factors and dendritic spines -- Chapter 6: Glial cell modulation of dendritic spine structure and synaptic function -- Chapter 7: Dendritic spines in learning and memory: from first discoveries to current insights -- Chapter 8: Steroid hormone interaction with dendritic spines: implications for neuropsychiatric disease -- Chapter 9: Morphological features of human dendritic spines.
    Abstract: This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.
    Type of Medium: Online Resource
    Pages: XV, 499 p. 123 illus., 103 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031361593
    Series Statement: Advances in Neurobiology, 34
    DDC: 612.8
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Clinical psychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Clinical Psychology. ; Psychiatry.
    Description / Table of Contents: Preface -- PART 1: To fear or not -- Disambiguating fear as an emotional state vs. threat detection. Molecular and Neural circuits of fear extinction. Psychological and theoretical elements on the concept of fear extinction. Neural circuit of fear extinction: psychophysiology -- PART 2: Individual differences in fear extinction -- The impact of sex differences and sex hormones on fear extinction. Impact of sleep on fear extinction. Impact of stress and exercise on fear extinction. Intersect between the intrinsic and extrinsic factors that modulate fear extinction -- PART 3: Psychopathology -- Fear extinction and its relevance to psychopathology. Developmental fear and its extinction imaging. Fear extinction and adult psychopathology -- Part 4: Therapeutics and neuromodulations of fear extinction -- Exposure therapy and other behavioral therapeutics targeting fear extinction circuits. Novel pharmacotherapeutics targeting fear extinction circuits. Reconsolidation and its link and impact on fear extinction. Technological advances in exposure therapy: virtual and augmented reality. Novel approaches using neurostimulation targeting fear extinction.
    Abstract: This book aims to provide the reader a neuroscientific understanding surrounding a very simple question: how do we learn not to fear? Exploring answers to this question is very important for two reasons. First, learning about the neural mechanisms of fear extinction is of relevance to everyone’s life - it is such a basic yet relevant question to our daily experiences. Therefore, understanding brain mechanisms of fear and its regulation is essential from a basic neuroscience point of view. Second, excessive fear and the inability to regulate its expression is one of the hallmarks of fear-, anxiety-, trauma-, and stressor-related psychopathologies. And as such, learning about how fear is acquired, stored, expressed, and regulated could help advance our understanding of the etiology of psychopathology, the maintenance of symptoms pertaining to failure to regulate fear, and could help us develop novel therapeutics to equip providers and patients with the tools to better quell their fears. The contributions contained in this book are provided by experts in the fields of basic and clinical neuroscience, experimental and clinical psychology, and neuropsychiatry. The contributions are organized to start the reader with basic definitions of how we define fear, how we study its neural circuits at the molecular and cellular levels, how to study human behavior and the brain using state-of-the art experimental and statistical tools, to how much fear contributes to psychopathology. This volume ends with current advances aimed to enhance the capacity to extinguish fear; a clinical result that would aid in the treatment of multiple psychiatric disorders, followed by a discussion on future directions of this highly important and relevant field.
    Type of Medium: Online Resource
    Pages: VIII, 387 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031430053
    Series Statement: Current Topics in Behavioral Neurosciences, 64
    DDC: 612.8
    Language: English
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  • 14
    Keywords: Neurosciences. ; Public health. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Public Health. ; Biomedical Research.
    Description / Table of Contents: 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection.
    Abstract: This book examines the correlation of the coronavirus disease-19 [CE1] [AAS2] (COVID-19) infection with sleep, circadian rhythm, and sleep disorders. The chapters of the book explore sleep problems during the COVID-19 pandemic and its association with psychological distress and also review the prevalence of clinical cases of insomnia, anxiety, and depression in COVID-19 patients. The book further presents the correlation between sleep, circadian rhythms, and immunity that contributes toward more severe COVID-19. It summarizes the evidence on the interplay between circadian biology, sleep, and COVID-19. The chapters of the book discuss the relationship between obstructive sleep apnea (OSA) and adverse COVID-19 outcomes. Towards the end, the book presents studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin and provides mechanistic insights into the potential therapeutic use of melatonin during the SARS-CoV-2 infection. The last chapter describes the publication output of sleep-related research during the pandemic and provides an overview and trends on sleep and covid-19 publication output. This book is an excellent source for neurologists, sleep specialists, and public health specialists.
    Type of Medium: Online Resource
    Pages: XXVI, 430 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819902408
    Series Statement: Progress in Sleep Research,
    DDC: 612.8
    Language: English
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  • 15
    Keywords: Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Description / Table of Contents: Sensory Regeneration in the Inner Ear: History, Strategies and Prospects -- Non-mammalian Hair Cell Regeneration: Cellular Mechanisms of Morphological and Functional Recovery -- Cell Junctions and the Mechanics of Hair Cell Regeneration -- Mammalian Hair Cell Regeneration -- Specification and Plasticity of Mammalian Cochlear Hair Cell Progenitors -- Inner Ear Cells from Stem Cells – a Path Towards Inner Ear Cell Regeneration -- Spiral ganglion neuron regeneration in the cochlea: regeneration of synapses, axons and cells -- Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear.
    Abstract: This volume provides a detailed update on progress in the field of hair cell regeneration with emphasis on more "prospective" views of the various facets of regeneration research. Sensory Regeneration in the Inner Ear: History, Strategies and Prospects Mark E. Warchol, and Jennifer S. Stone Non-mammalian Hair Cell Regeneration: Cellular Mechanisms of Morphological and Functional Recovery Madeleine Hewitt, David W. Raible, and Jennifer S. Stone Cell Junctions and the Mechanics of Hair Cell Regeneration Mark A. Rudolf, and Jeffrey T. Corwin Mammalian Hair Cell Regeneration Ruth Taylor, and Andrew Forge Specification and Plasticity of Mammalian Cochlear Hair Cell Progenitors Melissa M. McGovern, and Andrew K. Groves Inner Ear Cells from Stem Cells – a Path Towards Inner Ear Cell Regeneration Amanda Janesick, Eri Hashino, and Stefan Heller Spiral ganglion neuron regeneration in the cochlea: regeneration of synapses, axons and cells Steven H. Green, Sepand Bafti, Benjamin M. Gansemer, A. Eliot Shearer, Muhammad Taifur Rahman, Mark E. Warchol, and Marlan R. Hansen Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear Brandon C. Cox, John V. Brigande, and Bradley J. WaltersDr. Mark Warchol is Professor of Otolaryngology at Washington University School of Medicine in St. Louis. Dr. Jennifer Stone is Research Professor of Otolgaryngolldy/Head and Neck Surgery, University of Washington School of Medicine, Seattle. Dr. Allison Coffin is an Associate Professor in the Department of Integrative Physiology and Neuroscience at Washington State University Vancouver. Dr. Arthur N. Popper is Professor Emeritus and research professor in the Department of Biology at the University of Maryland, College Park. Dr. Richard R. Fay (Deceased) was Distinguished Research Professor of Psychology at Loyola University Chicago.
    Type of Medium: Online Resource
    Pages: XVI, 229 p. 44 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031206610
    Series Statement: Springer Handbook of Auditory Research, 75
    DDC: 612.8
    Language: English
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  • 16
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Zoology. ; Life sciences. ; Behavior genetics. ; Neuroscience. ; Zoology. ; Life Sciences. ; Behavioral Genetics.
    Description / Table of Contents: Chapter 1. Introduction to neurogenetics -- Chapter 2. Neurogenetic analysis in Caenorhabditis elegans -- Chapter 3. Regionalisation of the early nervous system -- Chapter 4. Early neurogenesis and gliogenesis in Drosophila -- Chapter 5. Neural stem cells and brain tumour models in Drosophila -- Chapter 6. Eye development in Drosophila: from photoreceptor specification to terminal differentiation -- Chapter 7. Neurogenetics of memory, learning and forgetting -- Chapter 8. Evolution and origins of nervous systems -- Chapter 9. Neural stem and progenitor cells in the mammalian brain -- Chapter 10. Models of neurodegenerative diseases.
    Abstract: This textbook provides students with knowledge of neurogenetics, neurogenesis, neuronal specification and function, neuronal networks, learning and memory formation, brain evolution, and neurodegenerative diseases. Students are introduced to topics of classical developmental genetics as well as modern molecular and neurogenetic methods. Using a wealth of examples from current research, the textbook takes a strong applied approach. Using animal models such as Drosophila melanogaster and Caenorhabditis elegans as well as mammalian systems, the interrelationships between genes, neurons, nervous systems, and behaviour under normal and pathological conditions are illustrated. The textbook aims encourage students to address biological questions in neurogenetics and to think about the design of their own experiments. It targets primarily master and graduate students in neurobiology, but is also a valuable teaching tool for instructors in these fields.
    Type of Medium: Online Resource
    Pages: VII, 212 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031077937
    Series Statement: Learning Materials in Biosciences,
    DDC: 612.8
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Endocrine glands. ; Immunology. ; Neuroscience. ; Endocrine System. ; Immunology.
    Description / Table of Contents: Part I. Concepts -- Chapter 1. A History of Immune and Neuroendocrine System Interactions -- Chapter 2. Philosophical Perspectives on Neuroendocrine-Immune Interactions: The Building Block Model and Complementary Neuro-Endocrine-Immune-Microbiota Systems Approaches -- Chapter 3. The Behavioural Immune System of Lower Vertebrates -- Part II. Regulatory Pathways -- Chapter 4. Cytokines and Hypothalamo-Pituitary-Adrenal Axis Activation: Now a Classic of Immune-Neuroendocrine System Interactions -- Chapter 5. Catecholamines and Immunomodulation -- Chapter 6. Neuroendocrine-immune Interactions in Major Depressive Disorder: Glucocorticoids and Glucocorticoid Receptors -- Chapter 7. Brain Fluids, Blood-Brain Interfaces, and Their Involvement in Neuroimmune Regulation During Development and in Adulthood -- Chapter 8. Neuropeptide Binding Autoantibodies Regulating Neuroendocrine Communications -- Part III. Modulation -- Chapter 9. Postnatal Development of Neuroimmune Responses -- Chapter 10. Sex Differences in Neuroendocrine-Immune Interactions -- Chapter 11. Biological Clocks and Immune Function -- Chapter 12. Influence of the Gut Microbiota on Neuroendocrine-Immune Interactions -- Part IV. Disease -- Chapter 13. Energy Balance and Neuroendocrine-Immune Regulation in Chronic Inflammatory and Neoplastic Diseases: An Evolutionary Perspective -- Chapter 14. Autonomic, Immune, Metabolic and Neuroendocrine Dimensions of Anorexia Nervosa: An Integrative View.
    Abstract: The concepts of the neuroendocrine system and the immune system emerged more or less simultaneously in the second half of the 20th century. Although these systems have a high degree of autonomy, it has also become clear that they interact in many ways and at different levels. This book focuses on the neuroendocrine and immune interactions that are fundamental to normal development and maintenance of health. The first introductory chapters are devoted to the historical and philosophical concepts within the field, as well as evolutionary considerations, offering critical interdisciplinary perspectives on the development of this field of research. Without attempting an exhaustive overview, the book then introduces some of the regulatory pathways that mediate interactions between the neuroendocrine and immune systems and examines modulating factors such as age and sex. In addition, several chapters address the importance of neuroendocrine-immune interactions in some disease states. Readers can expect to gain a broad perspective of neuroendocrine-immune interactions in development, health, and disease, along with a critical evaluation of current methods used in the field. Given its scope, the book is essential reading for undergraduate and graduate students with an interest in neuroendocrinology, neuroimmunology, and neuroscience, as well as postdoctoral fellows and established researchers seeking a comprehensive overview and historical perspective of the field of neuroendocrine-immune interactions.
    Type of Medium: Online Resource
    Pages: XIII, 386 p. 29 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031213588
    Series Statement: Masterclass in Neuroendocrinology, 13
    DDC: 612.8
    Language: English
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  • 18
    Keywords: Neurosciences. ; Neuroanatomy. ; Neurophysiology. ; Developmental neurobiology. ; Cognitive neuroscience. ; Neuroscience. ; Neuroanatomy. ; Neurophysiology. ; Development of the Nervous System. ; Cognitive Neuroscience.
    Abstract: This monograph, now in its 2nd edition with 31 new chapters and significant updates, is the first book of its kind written specifically for graduate students and clinicians. The monograph is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013; 2nd edition: 2022), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology and related areas. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. Essentials of the Cerebellum and Cerebellar Disorders makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. It is organized into easy to read and short chapters that are ideal for students and clinicians. The most common cerebellar disorders encountered in the clinic are covered. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from cerebellar laboratories and ataxia clinics throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar cellular biology and circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.
    Type of Medium: Online Resource
    Pages: XIV, 742 p. 182 illus., 127 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031150708
    DDC: 612.8
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Psychiatry. ; Neurology . ; Neuroscience. ; Psychiatry. ; Neurology.
    Description / Table of Contents: A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.
    Abstract: The Dictionary of Hallucinations, second edition, is an alphabetical listing of issues pertaining to hallucinations and other misperceptions. They can be roughly divided into four categories: 1. Definitions of individual hallucinatory symptoms 2. Medical conditions and substances associated with the mediation of hallucinations 3. Historical figures who are known to have experienced hallucinations 4. Miscellaneous issues Each of the definitions of individual hallucinatory symptoms includes: a definition of the term its etymological origin the year of introduction (if known) a reference to the author or authors who introduced the term (if known) a description of the current use a brief explanation of the etiology and pathophysiology of the symptom at hand (if known) references to related terms references to the literature The second edition of A Dictionary of Hallucinations serves as a reference manual for neuroscientists, psychiatrists, psychiatric residents, psychologists, neurologists, historians of psychiatry, general practitioners, and academics dealing professionally with concepts of hallucinations and other sensory deceptions. This new edition provides updated information and references, and includes newly discovered hallucinations, bringing together contributions by other authorities within the field, with all the entries edited by Prof. Blom.
    Type of Medium: Online Resource
    Pages: XXVI, 790 p. 604 illus., 364 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031252488
    DDC: 612.8
    Language: English
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  • 20
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Pharmacology. ; Neuroscience. ; Pharmacology.
    Description / Table of Contents: Chapter 1 Overview of the relationship between aluminum exposure and health of human being.-Chapter 2 The Chemistry of Human Exposure to Aluminum -- Chapter 3 Entry and Deposit of Aluminum in Brain -- Chapter 4 Aluminum as a CNS and immune system toxin across the life span.-Chapter 5 Occupational exposure to aluminum and cognitive impairment -- Chapter 6 Debated relationship between Exposure to Aluminum in Daily Life and Alzheimer’s Disease -- Chapter 7 Animal Model of Aluminum-Induced Alzheimer’s like Disease -- Chapter 8 Aluminum-induced AD-like Pathological Features.-Chapter 9 Aluminum induced neural cells death -- Chapter 10 Aluminum-Induced Electrophysiological Variation, Synaptic Plasticity Impairment, and Related Mechanism.-Chapter 11 Cross Talk Between Aluminum and Genetic Susceptibility -- Chapter 12 Epigenetic modification in aluminum-induced neuron death and synaptic impairment -- Chapter 13 Neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) -- Chapter 14 Alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects.
    Abstract: This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta—the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment. The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.
    Type of Medium: Online Resource
    Pages: XVIII, 313 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789819915927
    DDC: 612.8
    Language: English
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  • 21
    Keywords: Neurosciences. ; Neurology . ; Neurophysiology. ; Neuropharmacology. ; Neuroscience. ; Neurology. ; Neurophysiology. ; Neuropharmacology.
    Description / Table of Contents: Molecular Biomarkers.Somatic instability/Telomeres,- Genetic modifiers -- Current clinical trial biomarkers.-Pharmacodynamic biomarkers for Htt-lowering therapeutics.-Inflammatory biomarkers.-Sleep dysregulation markers.-Mitochondrial/Oxidative stress biomarkers.-Microbiomics -- Metabolomics.-Proteomics.-Transcriptomics.-Lipidomics.-Imaging marker overview.-Retinal imaging biomarkers -- MRI - non-invasive functional MRI measures -- The evolution of clinical trial methodology.-Digital biomarkers -- The future of telehealth -- Summary and future trends.
    Abstract: Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.
    Type of Medium: Online Resource
    Pages: XVI, 475 p. 42 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031328152
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Regenerative medicine. ; Stem cells. ; Neuroscience. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology.
    Description / Table of Contents: Part 1 General considerations -- Human iPS for clinical applications and cellular products -- 3D-printed iPS disease models -- Part 2 CNS iPSC and organoids -- iPS-derived neurons and brain organoids from patients (brain) -- iPS-derived RGCs (eye) -- iPS-derived glia (brain) -- iPSC to model blood-brain barrier endothelial cells -- Part 3 iPSC-derived nociceptive neurons -- IPSC-based peripheral nerve modeling -- Part 4 Non-neuronal specialized cell types -- iPSC-based drug screening of differentiated cardiomyocyte subtypes -- iPSC-based cardiac disease modeling: from cell to tissue -- iPSC-derived corneal endothelial cell -- iPSC-derived trabecular meshwork (eye) -- iPSC for in vitro disease modeling of diabetes.
    Abstract: Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has been lost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.
    Type of Medium: Online Resource
    Pages: VIII, 332 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031423499
    Series Statement: Handbook of Experimental Pharmacology, 281
    DDC: 612.8
    Language: English
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  • 23
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Earth sciences. ; Atmospheric science. ; Ecology . ; Oceanography. ; Water. ; Hydrology. ; Regional economics. ; Spatial economics. ; Human geography. ; Earth Sciences. ; Atmospheric Science. ; Biooceanography. ; Water. ; Regional and Spatial Economics. ; Human Geography.
    Description / Table of Contents: Chapter 1. Short to Medium Range Weather Forewarning System in India -- Chapter 2. Operational Seasonal Forecasting of the Southwest Monsoon Rainfall -- Chapter 3. Severe Weather Events over Indian Region: Insights from Ensemble Prediction System -- Chapter 4. Monsoon Variability and Change -- Chapter 5. Use of Remote Sensing in Weather and Climate Studies and Forecasts -- Chapter 6. Forecasting of Severe Weather Events -- Chapter 7. Weather and Climate Modelling -- Chapter 8. Operational Extended Range Forecast of Weather and Climate Over India and the Sectoral Applications -- Chapter 9. Frequency and Magnitude of Heat and Cold Waves over India -- Chapter 10. Economic Impacts of Air pollution and Fog in India and Prediction Efforts -- Chapter 11. Advances in Ocean State Forecasting and Marine Fishery Advisory Services for the Indian Ocean Region -- Chapter 12. Satellite-Based Marine Ecological Services for the Indian Ocean Region -- Chapter 13. Augmentation of Water—Can Oceans Help? -- Chapter 14. Emerging Blue Economy Paradigm and Developments in India -- Chapter 15. Coastal Research—Beach Restoration and Protection -- Chapter 16. Developing Ocean Technology -- Chapter 17. Deep Sea Mineral Resources and the Indian Perspectives -- Chapter 18. Tsunami Early Warning Services -- Chapter 19. Landslide Hazard and Monitoring -- Chapter 20. Seismic Microzonation of Indian Cities and Strategy for Safer Design of Structures -- Chapter 21. Earthquake Monitoring in India by National Center for Seismology, India.
    Abstract: This book collects research papers on the economic and social impact of earth sciences. It covers topics related to weather forecasting, climate modelling, monsoon variability, air pollution, heat and cold wave, deep sea mineral and living resources, ocean state monitoring, tsunami and earthquake monitoring, desalination, coastal research, etc. The book focuses on the activities of the Ministry of Earth Sciences, India, in promoting the societal and economic impacts of earth science research in a simple language and in the form of stories and case studies, so that people with basic science degree can understand them. .
    Type of Medium: Online Resource
    Pages: XVII, 432 p. 12 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811969294
    DDC: 550
    Language: English
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  • 24
    Keywords: Earth sciences. ; Climatology. ; Human ecology. ; Earth Sciences. ; Climate Sciences. ; Environmental Anthropology.
    Description / Table of Contents: The Living Planet -- The dawn of Gaia -- The early Earth crust (4.0-2.6 Ga) -- Early life -- Ica ages and atmospheric oxygenation -- The Ediacaran and Cambrian “explosion” of life -- Phanerozoic mass extinctions -- The Holocene -- The Anthropogenic catastrophe -- A burning planet -- Paleoclimate implications -- Climate zones shifts, ice melt and stadial cooling -- Future climate projections -- The nuclear nightmare.
    Abstract: This books presents a documentation and resulting perspectives regarding James Lovelock's multidisciplinary evolution theory. It looks at past and current climate changes and their consequences, including detailed accounts of the global warming. The connection between climate trajectories and extreme weather events, including tropical and arctic fronts, cyclones, fire storms, tropical storms, acidification, tsunami, floods, sea level rise, are referred to in connection with recent developments. The book updates earlier accounts regarding extreme weather events and mass extinctions.
    Type of Medium: Online Resource
    Pages: XV, 127 p. 87 illus., 81 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031237096
    DDC: 550
    Language: English
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  • 25
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Keywords: Earth sciences. ; Geophysics. ; Earth Sciences. ; Geophysics.
    Description / Table of Contents: How special is the Earth? -- The sun as a source of energy -- Understanding the greenhouse effect -- The Earth's climate system -- Climate change -- Effects of the climate system -- What can I do? -- Future view.
    Abstract: What is driving climate change? What impact does it have on the Earth's ecosystems, our environment, and us? What can I do? This book explains in a clear and understandable way the interrelationships, influencing factors and effects of the greatest challenge facing mankind: climate change. The team of authors presents over 100 aspects in clear language, each on a double-page spread. With impressive sketchnotes, professor and sketchnoter Katharina Theis-Bröhl illustrates and explains the sometimes simple, sometimes complicated issues always understandable. Because: Sketchnotes are not only beautiful to look at – they are also an effective mnemonic, a structural tool and an aid to crystallize the essentials. Comprehensible accompanying texts by Cecilia Scorza and Harald Lesch round off each topic in an informative way. With this book, you can understand the causes of climate change, discover the physical connections, and recognize both local and global impacts. You will learn about the role our location in the solar system plays, the feedback processes involved in global warming, and what it means when the oceans acidify. And ultimately, the question will be asked: How much time do we have left to act? From the contents How special is the Earth? – Understanding the greenhouse effect – The Earth's climate system – The climate change – Effects of climate change – What can I do? – A look ahead About the authors Harald Lesch is Professor of Theoretical Astrophysics at the Institute of Astronomy and Astrophysics at the University of Munich. For years, he has brought complex scientific and philosophical topics to the general public in an understandable and impressive way with numerous bestsellers and programs such as "Lesch's Cosmos". Climate change and climate protection are among his main topics. Cecilia Scorza holds a doctorate in astrophysics and is the coordinator of public outreach and education at the Faculty of Physics at the University of Munich. She has received, among others, the Neumann Prize for Didactics of the German Astronomical Society, the Scientix Prize of the EU and the Kepler Prize for Physics Education. Together with Harald Lesch and colleagues, she initiated the project "Climate Change: Understanding and Acting", which has been running with great success in German-speaking schools since 2018. Katharina Theis-Bröhl is a professor of physics, mathematics and materials science at Bremerhaven University of Applied Sciences. She uses sketchnotes in lectures and popular science talks to present complex issues in an understandable way. In 2019 and 2022, she organized the "Climate Week Bremerhaven" at Bremerhaven University of Applied Sciences, where scientists, students and the interested public could inform and exchange ideas. She is active in Scientists for Future.
    Type of Medium: Online Resource
    Pages: XIV, 163 p. 79 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662663721
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Earth sciences. ; Architecture. ; Design. ; Earth Sciences. ; Architecture. ; Design.
    Description / Table of Contents: Chapter 1 Denis Scott Brown Introduction -- Chapter 2 Life and Influences -- Chapter 3: Denise Scott Brown: Teacher -- Chapter 4 Denise Scott Brown: Writer and Theorist -- Chapter 6 Denise Scott Brown: Architect -- Chapter 7 Denise Scott Brown: Photographer -- Chapter 8 Denise Scott Brown: Ahead of Her and Our Time. The Vision that Never Ends.
    Abstract: This book is entirely dedicated to Denise Scott Brown. It informs readers about her life, analyzes her projects in both architecture and urban planning and offers a better understanding of her radical theories. The seven main chapters and the conclusion provide a comprehensive insight into the world of legendary Denise and complete the knowledge necessary to understand her as an architect, an urban planner, a theorist, and a professor. Each chapter is richly illustrated. At the very beginning of the book is a letter that Denise wrote to the author. Her words are an authentic testimony of her life after 1967.
    Type of Medium: Online Resource
    Pages: XIII, 295 p. 275 illus., 238 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031367816
    Series Statement: Springer Biographies,
    DDC: 550
    Language: English
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    Keywords: Geophysics. ; Geotechnical engineering. ; Geographic information systems. ; Geophysics. ; Geotechnical Engineering and Applied Earth Sciences. ; Geographical Information System.
    Description / Table of Contents: Geometric Reference Frames -- Combined IVS Contribution to the ITRF2020 -- An Experimental Combination of IGS repro3 Campaign’s Orbit Products Using a Variance Component Estimation Strategy -- The Correlations of the Helmert Transformation Parameters as an Additional Auxiliary Diagnostic Tool for Terrestrial Reference Frames Quality Assessment -- Shimosato Co-Location of the SLR and GNSS Stations -- Local Ties at SLR Station Riga -- Datum Problem Handling in Local Tie Surveys at Wettzell and Metsähovi -- Close Range Photogrammetry for High-Precision Reference Point Determination: A Proof of Concept at Satellite Observing System Wettzell -- Frame Accuracy of Combined EPN Weekly Coordinate Solutions -- The Atlantic Network of Geodynamic and Space Stations (RAEGE): A Spanish-Portuguese Infrastructure of Geodetic Stations -- ITRF Densification in Cyprus -- Geodetic Analyses at the National Geographic Institute of Spain -- Large-Scale Dimensional Metrology for Geodesy - First Results from the European GeoMetre Project -- Bureau of Products and Standards: Description and Promotion of Geodetic Products -- Physical Height Systems -- Can an Earth Gravitational Model Augmented by a Topographic Gravity Field Model Realize the International Height Reference System Accurately? -- Assessing Molodensky’s Heights: A Rebuttal -- On the Accuracy of Geoid Heights Derived from Discrete GNSS/Levelling Data Using Kriging Interpolation -- Gravimetric Geoid Modeling by Stokes and Second Helmert’s Condensation Method in Yogyakarta, Indonesia -- A Geodetic Determination of the Gravitational Potential Difference Toward a 100-km-scale Clock Frequency Comparison in a Plate Subduction Zone -- Validation of the Hellenic Gravity Network in the Frame of the ModernGravNet Project -- Global Gravity Field Modeling -- Combined Gravity Solution from SLR and GRACE/GRACE-FO -- Contribution of LARES SLR Data to Co-estimated Earth Geopotential Coefficients -- Determination and Combination of Monthly Gravity Field Time Series from Kinematic Orbits of GRACE, GRACE-FO and Swarm -- Topographic Gravity Field Modelling for Improving High-Resolution Global Gravity Field Models -- The Benefit of Accelerometers Based on Cold Atom Interferometry for Future Satellite Gravity Missions -- Kalman-Filter Based Hybridization of Classic and Cold Atom Interferometry Accelerometers for Future Satellite Gravity Missions -- Gravimetry by Nanoscale Parametric Amplifiers Driven by Radiation-Induced Dispersion Force Modulation -- Earth Rotation -- On the Improvement of Combined EOP Series by Adding 24-hour VLBI Sessions to VLBI Intensives and GNSS Data -- Investigating the Relationship Between Length of Day and El-Niño Using Wavelet Coherence Method -- Estimation of Earth Rotation Parameter UT1 from Lunar Laser Ranging Observations -- Surface Deformation Monitoring -- Determination of a GNSS-Based Velocity Field of the African Continent -- Vertical Land Motion at Tide Gauges Observed by GNSS: A New GFZ-TIGA Solution -- CyCLOPS: A National Integrated GNSS/InSAR Strategic Research Infrastructure for Monitoring Geohazards and Forming the Next Generation Datum of the Republic of Cyprus -- GNSS Positioning -- Dilution of Precision (DOP) Factors for Evaluating Observations to Galileo Satellites with VLBI -- On the Limits of State-of-the-Art GNSS Receivers in Frequency Transfer -- On the Effect of Antenna Calibration Errors on Geodetic Estimates: Investigation on Zero and Double Difference Approaches -- Estimation and Calibration of Codephase Center Correction Using the Empirical Mode Decomposition -- On the Potential of Image Similarity Metrics for Comparing Phase Center Corrections -- Multipath Characterization Using Ray-Tracing in Urban Trenches -- Bounding the Residual Tropospheric Error by Interval Analysis -- Precise Orbit Determination of CubeSats Using Proposed Observations Weighting Model -- Geodetic Atmospheric and Remote Sensing -- Optimal TEC Forecast Models Based on Machine Learning and Time Series Analysis Techniques – A Preliminary Study on the Ring of Fire -- Sensitivity of Shipborne GNSS Troposphere Retrieval to Processing Parameters -- Application of the Total Variation Method in Near Real-Time GNSS Tropospheric Tomography -- Comparison of the Effective Isotropic Radiated Power Parameter in CYGNSS v2.1 and v3.0 Level 1 Data and Its Impact on Soil Moisture Estimation -- Cross-Polarization Correction for Soil Moisture Retrieval Using GNSS SNR Data.
    Abstract: This open access volume contains selected papers of the 2021 Scientific Assembly of the International Association of Geodesy – IAG2021. The Assembly was hosted by the Chinese Society for Geodesy, Photogrammetry and Cartography (CSGPC) in Beijing, China from June 28 to July 2, 2021. It was a hybrid conference with in-person and online attendants. In total, the Assembly was attended by 146 in-person participants and 1,123 online participants. The theme of the Assembly was Geodesy for a Sustainable Earth. 613 contributions (255 oral presentations and 358 poster presentations) covered all topics of the broad spectrum considered by the IAG: geodetic reference frames, Earth gravity field modelling, Earth rotation and geodynamics, positioning and applications, the Global Geodetic Observing System (GGOS), geodesy for climate research, marine geodesy, and novel sensors and quantum technology for geodesy. All published papers were peer-reviewed, and we warmly recognize the contributions and support of the Associate Editors and Reviewers. .
    Type of Medium: Online Resource
    Pages: XII, 441 p. 265 illus., 251 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031295072
    Series Statement: International Association of Geodesy Symposia, 154
    DDC: 550
    Language: English
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    Keywords: Earth sciences. ; Natural disasters. ; Geographic information systems. ; Atmospheric science. ; Physical geography. ; Biogeography. ; Earth Sciences. ; Natural Hazards. ; Geographical Information System. ; Atmospheric Science. ; Earth System Sciences. ; Biogeosciences.
    Description / Table of Contents: 1. Vegetation Fires and Biomass Burning in South/Southeast Asia – An Overview -- Section I: Mapping , Monitoring and Modeling of Vegetation Fires -- 2. Wildfire monitoring using infrared bands and spatial resolution effects -- 3. Status and Drivers of Forest Fires in Myanmar -- 4. Vegetation Fires and Entropy Variations In Myanmar -- 5. Crop residue burning and forest fire emissions in Nepal -- 6. Firewood Burning Dynamics by the Sri Lankan Households: Trends, Patterns, and Implications -- 7. Burnt Area Signal Variations in Agriculture and Forested Landscapes of India - A Case Study Using Sentinel A/B Synthetic Aperture Radar -- 8. Application of Interferometry SAR for Monitoring of Peatland Areas– Case Studies in Indonesia -- 9. Active Fire Monitoring of Thailand and Upper ASEAN by Earth Observation Data: benefits, lessons learned and what still needs to be known -- 10. Detecting Vegetation Regrowth after Fires in Small Watershed Settings Using Remotely Sensed Data and Local Community Participation Approach -- 11. Long-Term Spatiotemporal Distribution of Fire over Maritime Continent and their Responses to Climate Anomalies -- 12. Vegetation Fires in Laos - An Overview -- 13. Vegetation Fires, Fire Radiative Power and Intermediate Fire Occurrence Intensity (IFOI) Hypothesis Testing in Myanmar, Laos and Cambodia -- 14. Analyzing fire behavior and calibrating a fire growth model in a seasonal dry tropical forest area -- Section II: Greenhouse Gas Emissions and Air Pollution -- 15. Spatiotemporally resolved pollutant emissions from biomass burning in Asia -- 16. Twenty-year variations of aerosol optical depth over Asia in relation to anthropogenic and biomass burning emissions -- 17. Light Absorption Properties of Biomass Burning Emissions in Bangladesh: Current State of Knowledge -- 18. Remote Sensing of greenhouse gases and aerosols from agricultural residue burning over Pakistan -- 19. A comparative study of energy, emissions and economic efficiency of various cookstoves in Nepal -- 20. Estimation of Ultrafine Particulate Matter Emissions from Biomass Burning Using Satellite Imaging and Burn Severity -- 21. Characteristics of Transboundary Haze and General Aerosol over Pulau Pinang, Malaysia -- 22. Measurements of atmospheric carbon dioxide emissions from fire-prone peatlands in Central Kalimantan, Indonesia, using ground-based instruments -- 23. Air Pollution Caused by Deep Peatland Fire in Central Kalimantan -- 24. Chemical Speciation of PM0 Emissions from Peat Burning Emission in Central Kalimantan, Indonesia -- 25. GHG emissions estimation from Peatland fires in Indonesia – Review and Importance of Combustion Factor -- 26. Forest Fire Emissions in Equatorial Asia and Their Recent Delay Anomaly in the Dry Season -- Section III: Air Pollution Modeling and Decision Support Systems -- 27. Impact of vegetation fires on regional aerosol black carbon over South and East Asia -- 28. Detection and Modeling of South Asian Biomass Burning Aerosols from both Macro- and Micro-perspective -- 29. Remote sensing of agricultural biomass burning aerosols, gaseous compounds, long-distance transport and impact on air quality -- 30. Agricultural fires in Northeast China: Characteristics, Impacts, and Challenges -- 31. Air Pollution Modelling in Southeast Asia – An Overview -- 32. Trace gases and air quality in Northwestern Vietnam during recurrent biomass burning on the Indochina Peninsula since 0 – Field Observations and Atmospheric Simulations -- 33. Southeast Asian Transboundary Haze in the Southern Philippines, and Meteorological Drivers -- 34. An Operational Fire Danger Rating System for Thailand and Lower Mekong Region: Development, Utilization, and Experiences -- 35. Fires Hotspot Forecasting in Indonesia Using Long Short-Term Memory Algorithm and MODIS Datasets.
    Abstract: Vegetation fires are prevalent in several regions of the world, including South/ Southeast Asia (S/SEA). Fire occurrence and spread are influenced by fuel type, topography, climate, weather, and lightning, among others. In S/SEA, human-initiated fires are responsible for most of the incidents in addition to natural factors. Through biomass burning, vegetation fires can emit large quantities of greenhouse gases and air pollutants such as CO2, CO, NOx, CH4, non-methane hydrocarbons, and other chemical species, including aerosols that can affect air quality and health at both local and regional scales. Moreover, biomass burning pollutants can travel long distances and impact regional climate. Therefore, quantifying vegetation fires and their impacts is critical at different spatial scales. This book includes contributions from renowned researchers from the USA and South/ Southeast Asia on various fire-related topics. The contributions resulted from several international meetings and workshops organized in Asia as part of the South/ Southeast Asia Research Initiative (SARI) under the NASA Land-Cover/Land-Use Change Program. The book is divided into three sections, each containing multiple contributions: a) Mapping, Monitoring, and Modeling of Vegetation Fires, b) Greenhouse Gas Emissions and Air Pollution, and c) Air Pollution Modeling and Decision Support Systems. These sections are preceded by an introductory chapter by the editors that highlights the latest satellite-derived fire statistics and the current fire situation in S/SEA. This book will be a valuable resource for remote sensing scientists, geographers, ecologists, atmospheric, climate, environmental scientists, including policymakers, and all who wish to advance their knowledge on vegetation fires and emissions in South/Southeast Asia.
    Type of Medium: Online Resource
    Pages: XXIX, 602 p. 245 illus., 231 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031299162
    DDC: 550
    Language: English
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    Keywords: Physical geography. ; Geotechnical engineering. ; Mining engineering. ; Environmental monitoring. ; Pollution. ; Machine learning. ; Earth System Sciences. ; Geotechnical Engineering and Applied Earth Sciences. ; Mining and Exploration. ; Environmental Monitoring. ; Pollution. ; Machine Learning.
    Description / Table of Contents: Cutting Edge Exploration and Drilling Technologies -- Challenges in deep Opencast, Highwall, Offshore and Placer Mining -- Transition from Opencast to Underground mining -- Mass Production Technologies in deep underground mines -- Application of Artificial Intelligence, Machine Learning, Data Analytics in Mine Automation -- Advancement in Explosives and Blasting Techniques -- Extraction and utilisation of Critical Minerals and Rare Earth Elements -- Application of Information and Communication Technology (ICT) in Smart Mining -- Innovations in Oil and Gas Industry.
    Abstract: Rising concern about climate change and strong societal expectations with increasing complexities of mineral deposits being mined, call for more innovative exploration and exploitation technologies with higher productivity and recovery including eco-friendly strategies and policies in place for long term sustainability of the mineral Industry. It is now ardently necessary to identify and define the best mining practices addressing societal needs. In view of these, The Mining, Geological and Metallurgical Institute of India (MGMI), established way back on 16th January 1906, and one of the oldest institutions of this kind in the world, is organizing the 10th Asian Mining Congress (AMC) during November 06-09, 2023 in Kolkata, India with the Theme, “Roadmap for Best Mining Practices vis-à-vis Global Transformation”. The AMC and International Mining Exhibition (IME), held concurrently, are flagship international events organized by MGMI biennially since its centenary year. This series have provided ample opportunities to all stakeholders including practicing engineers, machinery manufacturers, planners, regulators, academicians, scientists and policy makers, for sharing their knowledge, experience and expertise and exhibit their products that can benefit the mining and mineral industries not only in the Asian region but also globally. This proceeding of 10th AMC contains the articles written by eminent persons and stalwarts in their respective domains. It is a collection of contemporary articles narrating recent advancements in mining sector.
    Type of Medium: Online Resource
    Pages: XVII, 490 p. 290 illus., 215 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031469664
    Series Statement: Springer Proceedings in Earth and Environmental Sciences,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geophysics. ; Geology. ; Atmospheric science. ; Geotechnical engineering. ; Geophysics. ; Geology. ; Atmospheric Science. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: - Acoustic wave reflection coefficient from large-scale irregularities weakly non-Gaussian sea surface -- Numerical modeling of wind currents in the Sivash Gulf (Sea of Azov) -- Metamorphic Conditions Carbonaceous Rocks Framing of the Larino Granite-Gneiss Dome (South Ural, Russia) -- Chemical and microbiological features of the coastal waters of the Black and Azov Seas in summer season -- On the issue of “true polar wander” phenomenon and its alternative physical interpretation based on galactic model -- The Black Sea deep-water circulation under climatic and anomalous atmospheric forcing -- Determination of the initial Cs140 concentration field in the Black Sea after the Chernobyl accident -- Analytical solution of the evolutionary model of wind currents -- Assessment of the wave asymmetry contribution to the dynamics of sediment fractions in the coastal zone of the Kalamitsky Gulf -- Changes in the repeatability of dangerous winds in the arctic zone of Siberia for the summer months in the period 1961-2020 -- Repeatability of dangerous winds over the sea of Azov and Black sea and their coasts -- Investigation of the spatio-temporal heterogeneity of the snow thickness at the site of the Lomonosov MSU in winter of 2022/2023 -- Experimental estimates of the rate of deepening of individual thermals -- Interaction of nonlinear waves taking into account planetary scale blems -- Hydrodynamic interaction between two systems of intense intra-mantle vortices as a possible cause of the connection between distant earthquakes -- Wave motions of a liquid in a rotating annular layer -- The problem of propagation of plane long waves in a nonhomogeneous liquid over a deformable bottom -- Technogenic gold-bearing mineralization of eastern orenburg region -- Morpholitosystem of Piltun lagoon (Sakhalin region) -- Propagation of tsunami waves in the Forked Bays -- Assessment of the state of the hydrosphere in the zone of development of oil fields of the Western Orenburg region -- Biogenic morpholitogenesis on sea coasts Sakhalin island -- Organogenic morpholitosystem of the Nabil lagoon -- Concept of a structural system of a large-panel residential building with a free layout considering the requirements for earthquake resistance during construction in a sharply continental climate -- Geophysical investigation of the ski slope snow thickness at “Vorob'yovy Gory” hills in winter period 2022/23 -- Statement of individual problems of the dynamics of stratified media with allowance for compressibility -- Formation of modern technogenic processes in historical urban areas -- Carbon sequestration in managed salt wetlands (Carbon polygon) -- Methodology for determining the content of BTEX and oils in water with various external parameters -- Abrasion-denudation cycle levels as the basis of paleoreconstructions on rising coasts -- Exact Analytical Expression for Maximum Heat Flux from Impulsive Sources of Charged Particles in Magnetic Field. .
    Abstract: This book includes new results of theoretical and experimental studies of various scales of the processes occurring on the earth including the lithosphere, atmosphere, and hydrosphere. Intensive development of research in these areas is due to several factors: 1) the widespread introduction of computer technology, allowing the calculation of complex phenomena; 2) the invention and improvement of a new generation of geophysical instruments such as remote observation systems based on ships, aircraft, and satellites, providing a large amount of data to objectively reflect a broad picture of the processes; and 3) the development of measurement techniques, creating opportunities for controllable and reproducible laboratory data acquisition for generation of new ideas and concepts. Their recent developments have facilitated our research and understanding of these academic fields. The book enriches the understanding of the geophysical processes taking place in various environments (lithosphere, hydrosphere, and atmosphere), including the anthropogenic one, and it further contributes to their development. This book is a valuable resource for specialists working in the oil, gas, and engineering industry to improve their understandings of the field.
    Type of Medium: Online Resource
    Pages: VII, 309 p. 106 illus., 85 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819965755
    Series Statement: Springer Geology,
    DDC: 550
    Language: English
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    Keywords: Earth sciences. ; Physical geography. ; Environment. ; Environmental monitoring. ; Earth Sciences. ; Earth System Sciences. ; Environmental Sciences. ; Environmental Monitoring.
    Description / Table of Contents: Section 1. Environmental Earth Sciences -- Section 2. Geomorphology, Landslides, Soil Science, Paleoclimate, Geoarchaeology -- Section 3. Caves and Karst, a special session on the occasion of the International Year of Caves and Karst (2021).
    Abstract: This edited book is based on the accepted papers for presentation at the 1st MedGU Annual Meeting, Istanbul, 2021. With two parts spanning a large spectrum of environmental, geomorphological and geoarcheological topics and a third part on caves and karst, which includes research studies gathered on the occasion of the International Year of Caves and Karst (2021), this book presents a series of newest research studies that are nowadays relevant to Middle East, Mediterranean region, and Africa. The book gives a general overview on current research, focusing on geoenvironmental issues and challenges in environmental management in the Middle East and Mediterranean region and surrounding areas. It offers a broad range of recent studies that discuss the latest advances in geomorphology, landslides, soil science, paleoclimate, and geoarcheology. It also shares insights on cave and karst studies including speleology, cave and karst explorations, geomorphology, hydrogeology, geoethics, prehistoric eras in karst, geotectonics, and the nexus between human activities and karst sustainability.
    Type of Medium: Online Resource
    Pages: XXXI, 258 p. 150 illus., 137 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031429170
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 550
    Language: English
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    Keywords: Earth sciences. ; Physical geography. ; Environment. ; Natural disasters. ; Financial risk management. ; Geotechnical engineering. ; Earth Sciences. ; Earth System Sciences. ; Environmental Sciences. ; Natural Hazards. ; Risk Management. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Geoethics to face natural risks by improving societal resilience -- Multi-hazards risk assessment at the Canary Islands -- Risk-informed decision-making on volcanic hazards -- Geoethics: the missing piece in the separation of responsibility between volcanologists and decision-makers -- Earthquakes, volcanoes and God: changing perspectives on the importance of religion as an important influence in cultural responses -- Toward a multi-hazard assessment at Etna volcano (Italy): the PANACEA project -- From multi-hazard to multi-risk at Mount Etna: approaches and strategies of the PANACEA project -- The Role of the individual in successful disaster management in pre-industrial societies: the cases of the Southern Italy and the Azores -- Historical volcanism as a source of knowledge to assess the vulnerability of population settlements in the Azores: some thoughts -- A proposal for systematization of vulnerability elements and parameters in volcanic risk assessment.
    Abstract: This book comprises the selected proceedings of the 3rd International Workshop on Natural Hazards (NATHAZ’22), Angra do Heroísmo, Terceira Island, Azores, 2022. The book interests all researchers and practitioners in Earth Sciences, Volcanic Risks, Natural Hazards, Geoethics, Environmental Sciences and Engineering. Terceira is a volcanic island with volcanic systems with caldera (Cinco Picos, Guilherme Moniz, Santa Bárbara and Pico Alto central volcanoes) and an active fissural zone defined by various alignments of small volcanic cones, lava domes and fault zones. The agricultural landscape, the natural and forest reserve, as well as the natural pools make the island a unique place to visit. The historic downtown of Angra do Heroísmo is a UNESCO world heritage, and several iconic buildings witness the island’s geodynamic history. Natural hazards result from a threat of a naturally occurring event that will have a negative effect on humans. That damaging effect is often called natural disasters. Among the natural hazards and potential disasters to be considered are: earthquakes, volcanic eruptions, landslides, subsidence, floods, droughts and coastal erosion. In addition, anthropogenic hazards occur as a result of human interaction with the environment. They comprise technological risks due to exposure to hazardous substances in the environment. Natural systems in different frameworks require a comprehensive understanding of climatology, geology, hydrology and volcanic data, processes and dynamics. Thus, it is important to perform hazard and risk assessment studies to accomplish hazard mitigation. In addition, it highlighted the role of variability and climate change in Earth systems. Furthermore, an accurate understanding of the natural systems and interactions with engineering, geodiversity and natural resources is vital to the entire socioeconomic sector. This book is expected to offer an overview of natural hazards in model regions in Europe, America, Asia and the Atlantic islands. It gives new insights into the characterization, assessment, protection, and modelling of geological hazards, volcanic systems, urban areas, coastal zones and engineering approaches by international researchers and professionals. The scientific committee comprises lead geoscientists, natural hazards related practitioners, and academics worldwide. The main topics include: 1. Multi-hazards and risks: sustainable society, disasters and geoethics 2. Natural hazards and assessment: rock falls, landslides, urban planning and management 3. Sustainable Earth systems: hazards and climate change 4. Terceira Island geology and geodiversity: meeting volcanological hazards in the Azores.
    Type of Medium: Online Resource
    Pages: XXII, 230 p. 111 illus., 104 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031250422
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 550
    Language: English
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    Keywords: Physical geography. ; Water. ; Hydrology. ; Climatology. ; Ecology . ; Earth System Sciences. ; Water. ; Climate Sciences. ; Ecology.
    Description / Table of Contents: Section 1: Atmospheric Sciences, Meteorology, Climatology, Oceanography -- Section 2: Biogeochemistry, Geobiology, Geoecology, Geoagronomy -- Section 3: Environmental Earth Sciences and Geohazards -- Section 4: Hydrology, Hydrochemistry, Hydrogeology.
    Abstract: This book gives a general overview on current research focusing on geoenvironmental issues and challenges in hydrogeosciences in the Middle East and Mediterranean region and surrounding areas. The book is based on the accepted papers for oral/poster presentations at the 3rd Springer Conference of the Arabian Journal of Geosciences (CAJG-3). Studies discuss the latest advances in geoenvironmental and hydrogeosciences from diverse backgrounds including climate change, geoecology, biogeochemistry, water resources management, and environmental monitoring and assessment. It shares insights on how the understanding of ecological, climatological, oceanic, and hydrological processes is the key for improving practices in environment management. It is of interest to scientists, engineers, practitioners, and policymakers in the field of environmental sciences including climatology, oceanography, ecology, biogeochemistry, environmental management, hydrology, hydrogeology, and geosciences in general. In particular, this book is of great value to students and environment-related professionals for further investigations on the state of earth systems.
    Type of Medium: Online Resource
    Pages: XXIX, 271 p. 181 illus., 166 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031438035
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 550
    Language: English
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    Keywords: Geophysics. ; Geotechnical engineering. ; Archaeology. ; Geophysics. ; Geotechnical Engineering and Applied Earth Sciences. ; Archaeology.
    Description / Table of Contents: Landslide mitigation measures for the conservation of the archaeological site of Orongo (Easter Island-Chile) -- Conservation polices and mitigation measures for the Akapana Pyramid in the Tiwanaku archaeological site (Bolivia) -- Multiscale analysis of geohazards affecting the Alhambra (Spain) Cultural Heritage -- Rock mechanic characterization and 3D Kinematic analysis of Katsky pillar (Georgia) -- Petrological study on the Roman mortars from Kom El-Dikka Archaeological Site (Alexandria, Egypt) -- Electrochemical desalination of salt infected brick masonry applying a double electrode system -- Keynote: Investigation and preservation of historic foundations -- Keynote: Preventive Conservation of the Central Tower of Bayon Temple under Global Warming: Case Study in Soil Filled Foundation and Character Defining Elements of Authenticity of Foundation in Angkor, Cambodia -- Slope instability induced by climate changes on the UNESCO Etruscan necropolis (Tarquinia, Central Italy) -- Keynote: NRIAG effort to mitigate natural and geotechnical risk in cultural heritage site -- The Potential and Limitations of Electrical Resistivity and Magnetic Methods for Characterizing Highly Terrainous Archaeological Site: A Case Study At Tell Dibgou, Egypt -- The implementation of shallow geophysical survey for detection of some buried archaeological structures in Aswan city, Egypt -- The use of InfraRed Thermography (IRT) for the protection and conservation of rupestrian CH sites affected by slope instabilities -- Ground Penetrating Radar for investigating painted walls and floors of ancient buildings -- Frozen mounds of Altay mounting geophysical studies -- Keynote: Developments in the digital documentation of tangible Cultural heritage. Advances in data acquisition, processing methods and curating -- Usage of laser scanning system to document the historical heritage of Beet Al Qadi, Cairo -- An HBIM Holistic Approach for Rehabilitation of Heritage Buildings -- Keynote: Geophysics' role in investigating and mitigating groundwater hazards on archaeological sites: Case studies from "Sphinx -Giza, Kom Ombo Temple-Aswan and Hawara Pyramid-Fayoum -- Hydrogelogical hazard assessment and monitoring of Maya Devi Temple World Heritage sites in Lumbini (Nepal): the Birthplace of the Lord Buddha -- Water Infiltration and Waterproofing of Susan-ri Tomb (North Korea) -- Monitoring cultural heritage sites affected by geohazards -- Innovative structural monitoring as tool of preservation and valorisation of monumental architectures: the case of Neptune Temple in Paestum IT -- Structure Stability Analyses of Chapels Dedicated to Wives of Amun Using Non-Contact Techniques, Madinet Habu temple – Luxor – Egypt -- Integrated characterization of Apulian hypogean cultural heritage (Italy) -- Geological control on the evolution of stability of Theban tombs at Sheikh ‘Abd el-Qurna, Luxor, Egypt -- Keynote: Archeoseismology and the Impact of Large Earthquakes on Cultural Heritage -- Integrated Geoscience Investigations in Hittite Imperial Sites Affected by Earthquakes -- Multi-Scenario Physics-Based Seismic Hazard Assessment of Cultural Heritage Sites -- State of buildings and related damage after the earthquake of 1856 in Jijel (Algeria). Considerations for seismic hazard assessment in Jijel and Skikda (Algeria) -- Seismic hazard assessment of a cultural heritage minaret in Cairo -- Keynote: Analysis, integration and interpretation of Big Earth data in the Copernicus Era for the documentation, monitoring and preservation of natural and cultural heritage -- The potential of satellite interferometry for geohazard assessment in cultural heritage sites -- Instability processes and SAR data analysis in the Pompeii archeological park -- Remote Sensing applications for Cultural Heritage Sites Sustainability: case studies form Egypt -- Rome walls satellite monitoring and protection by prothego methodology -- The project of Parco Archeologico del Colosseo and the Italian network of archaeological parks: from satellite monitoring to conservation and preventive maintenance policies -- Adaptation, traditions and conservation: The Case of the Asante Traditional Buildings World Heritage Site in Ghana -- Management of Cultural Assets in Sudan from the Perspective of Sustainable Development Goals -- Improvement the State of Conservation of the Georgian Rock-cut Heritage through the Multidisciplinary Approach -- The Aswan declaration.
    Abstract: This book presents up-to-date geoscience technologies for heritage investigations and conservation, covering various sub-disciplines of geophysics, geodesy, 3D laser scanning technology, hydrogeology, and rock mechanics applied to the exploration of new heritage sites, mapping and visualization, as well as hazard mitigation. The current shift toward interdisciplinary ways of thinking highlights the added value of merging arts with sciences and other disciplines for better management and preservation of cultural heritage. Featuring advanced scientific investigations in 40 case studies around the globe, the book demonstrates how a better understanding of natural processes coupled with conservation approaches, mainly based on sustainable practices such as the use of traditional knowledge in recovery techniques and building local capacities, can ensure effective conservation.
    Type of Medium: Online Resource
    Pages: XI, 734 p. 565 illus., 538 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031138102
    Series Statement: Springer Geology,
    DDC: 550
    Language: English
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    Keywords: Physical geography. ; Environmental management. ; Environmental health. ; Environment. ; Earth System Sciences. ; Environmental Management. ; Environmental Health. ; Environmental Sciences. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1. Urbanization and emissions of pollutants -- Chapter 2. Spatial distribution of emerging pollutants in multimedia -- Chapter 3. Source identification and emission estimation of emerging pollutants -- Chapter 4. Multimedia modeling and simulation of contaminants transportation and fate -- Chapter 5. Exposure pathways and human risks of emerging pollutants -- Chapter 6. Ecological risks of emerging pollutants: methodology and applications -- Chapter 7. Conclusion and perspectives.
    Abstract: This book characterizes the major pollution patterns of emerging contaminants, such as sources, emission effluents, temporal and spatial distributions, multi-media transportation and transformation processes, exposure pathways to ecosystems and humans, and ecological risks. Based on this, it establishes an urbanizing region management concept and highlights how urbanization and its regional ecology have evolved into a more integrated vision. It also decouples the relations between urbanization and emissions of emerging pollutants that are framed within a broad socio-ecological context considering institutions, policies, and governance. All the theory, methods, and case studies have been taken from the authors’ publications, which have undergone rigorous international peer review. The book presents the spatial distribution, pathways, and flow diagrams of the pollutants as well as the interactions between urbanization and regional pollution and includes detailed figures and pictures. It also investigates ecological risk characterization and expression using maps based on geographic information systems to illustrate the general profile and the spatial variation of risks. The book is a valuable resource for postgraduates, researchers, academics, environmental NGOs, and regional managers such as urban planners, environmental agency staff, legal regulators, and decision makers. Bridging the gap between environmental science and policy, it offers interdisciplinary theory, approaches, and case studies that facilitate applications of frontier science in ecology and environmental science to regional social and economic development.
    Type of Medium: Online Resource
    Pages: XXXIX, 372 p. 198 illus., 186 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811996306
    DDC: 550
    Language: English
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  • 36
    Keywords: Geophysics. ; Water. ; Hydrology. ; Environmental management. ; Artificial intelligence. ; Geophysics. ; Water. ; Environmental Management. ; Artificial Intelligence.
    Description / Table of Contents: Assessment of Water Consumers Literacy -- Machine learning applications in sustainable water resource management: A systematic review -- Remote Sensing and Machine Learning Applications for the Assessment of Urban Water Stress: A Review -- Role of Artificial Intelligence in Water Conservation with special reference to India -- Remote sensing and GIS based techniques for monitoring and conserving water on newly developed farmlands -- A Comprehensive Review on Mapping of Groundwater Potential Zones: Past, present and future recommendations -- Geographic Information System and Remote Sensing in deciphering groundwater potential zones -- Remote Sensing & GIS based monitoring and management of coastal aquifers and ecosystem -- Hydrogeomorphological mapping of groundwater potential zones using multi-influence factor (MIF) and GIS techniques: A case study of Vishav watershed, western Himalayas -- GIS-based disaster risk analysis of floods using certainty factor (CF) and its ensemble with deep learning neural network (DLNN): A case study of Dima Hasao district of Assam -- Geospatial and Analytical Hierarchical Techniques to assess the groundwater potential areas in Kanyakumari district, Tamil Nadu -- Application of Remote Sensing and GIS in Mapping Groundwater Potential Zones through Fuzzy Integration in Kodavanar Watershed, A part of Amaravathi Basin, Tamil Nadu -- Morphometric analysis using geospatial techniques in the Pandameru River Basin, Anantapur District, Andhra Pradesh, India -- Ground Water Quality assessment using Water Quality Index and Geographical Information System of Mogamureru River Basin, Y.S.R. District, A.P., India -- Using Geo-spatial Technologies for Land and Water Resource Development Planning: A Case Study of Tirora Tehsil, India -- Delineation of Seawater Intrusion into freshwater aquifers by using VES & GIS in the Kakinada Region, East Godavari District, Andhra Pradesh, India -- . Systematic approach of groundwater resources assessment using remote sensing and multi-influence factor (MIF) techniques in Medchal Mandal, Telangana State, India -- Remote sensing snd GIS Application for Rainwater Harvesting and Groundwater Recharge to Secure Sustainable Groundwater Future of Adikavi Nannaya University, Rajamahendravaram, India.
    Abstract: This book deals with the role of emerging technologies such as remote sensing and GIS and artificial intelligence/machine learning in water supply, conservation and management for sustainable development. These are low-cost new technologies that address current challenges dealing with large data sets, such as identifying spatial and temporal variations in water quality parameters and contaminants, groundwater potential zones and water supply and management issues. This book is helpful to show the paths of reducing the burden of time and cost and is the alternative options for the conventional practices in water supply, conservation and management. Further, the outcomings of this book are helpful for policy makers, researchers and readers.
    Type of Medium: Online Resource
    Pages: XIV, 384 p. 99 illus., 85 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031352799
    Series Statement: Springer Water,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Geophysics. ; Geographic information systems. ; Geomorphology. ; Geophysics. ; Geographical Information System. ; Geomorphology.
    Description / Table of Contents: Classical horizontal references of Albania -- Classical vertical references of Albania -- Modern references in Albania -- Modern vertical reference of Albania -- Gravimetric reference of Albania -- Mathematical relations between the references of Albania -- Models of transformation of 2-D coordinates -- Transformation of heights.
    Abstract: This book addresses the problems of mathematical relations between global and classical coordinate references from the practical applications point of view. It presents a large cartographic and numerical information set, which provides great values for practical and academical use based on the classical Albanian coordinative reference (ALB1986/ALB1987). This information is reflected from the positional point of view in the new modern Albanian satellite reference ALBPOS (Albanian Positioning System) or ALBCORS (Albanian Continuous Operation Reference Stations System). The main purpose of this Monograph is to summarize coordinative references applied in Albania in different periods, both classical and modern. Relevant transformation models between traditional/classical reference ALB1986 / ALB1987 and GNSS satellite reference are presented. The book furthermore recommends the mathematical models of the relationship in plan and height, between the Albanian classical reference and the global/European coordinate references (ITRF, EUREF). It serves to professionals involved in fundamental geodetic works as well as all working with GNSS or developing GIS applications.
    Type of Medium: Online Resource
    Pages: XXIII, 105 p. 71 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031253669
    Series Statement: SpringerBriefs in Earth System Sciences,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Earth sciences. ; Physical geography. ; Conservation biology. ; Ecology . ; Archaeology. ; Paleontology . ; Earth Sciences. ; Physical Geography. ; Conservation Biology. ; Archaeology. ; Paleontology.
    Description / Table of Contents: Introduction -- Part 1- People and Caves in Australia -- Part 2 - ‘Hard’ rock karst developed in Neoproterozoic and Palaeozoic carbonates -- Part 3 - ‘Soft’ rock karst developed in Tertiary and Quaternary limestones -- Part 4 – Pseudokarst -- Part 5 – Cave contents.
    Abstract: This book, part of the series Cave and Karst Systems of the World, begins with a review of the interaction between people and caves in Australia (including conservation), followed by descriptions of the spectacular cave diving sites, before comprehensively covering all the major carbonate and noncarbonate karst areas, subdivided by rock type and region, and including the origin of the caves. This is followed by broad overviews of cave minerals and speleothems, cave biology and cave fossils. Each section was written by one or more specialists in the topic and is illustrated by clear diagrams and superb colour photos. The book emphasises the unique aspects of the Australian karst, including the variability in the age of the caves (very old to very young) and the impact of isolation on the stygofauna, as well as the vertebrate fossils preserved in the caves. Written in an easy-to-read style, the book is a primary reference guide to Australian karst and represents a valuable asset for anyone interested in the topic, not only cavers and academics.
    Type of Medium: Online Resource
    Pages: XII, 398 p. 215 illus., 191 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031242670
    Series Statement: Cave and Karst Systems of the World,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geophysics. ; Planetary science. ; Statistics . ; Geophysics. ; Planetary Science. ; Applied Statistics.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Scalar time series -- Chapter 3. Bivariate time series analysis -- Chapter 4. Analysis of trivariate time series -- Chapter 5. Conclusions and recommendations.
    Abstract: This book presents an easy-to-use tool for time series analysis and allows the user to concentrate upon studying time series properties rather than upon how to calculate the necessary estimates. The two attached programs provide, in one run of the program, a time and frequency domain description of scalar or multivariate time series approximated with a sequence of autoregressive models of increasing orders. The optimal orders are chosen by five order selection criteria. The results for scalar time series include time domain stochastic difference equations, spectral density estimates, predictability properties, and a forecast of scalar time series based upon the Kolmogorov-Wiener theory. For the bivariate and trivariate time series, the results contain a time domain description with multivariate stochastic difference equations, statistical predictability criterion, and information for calculating feedback and Granger causality properties in the bivariate case. The frequency domain information includes spectral densities, ordinary, multiple, and partial coherence functions, ordinary and multiple coherent spectra, gain, phase, and time lag factors. The programs seem to be unique and using them does not require professional knowledge of theory of random processes. The book contains many examples including three from engineering.
    Type of Medium: Online Resource
    Pages: XI, 199 p. 97 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031168918
    Series Statement: Progress in Geophysics,
    DDC: 550
    Language: English
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    Keywords: Earth sciences. ; Geology. ; Nuclear engineering. ; Earth Sciences. ; Geology. ; Nuclear Energy.
    Description / Table of Contents: regional geological background of ordos basin -- geological characteristics of uranium-bearing rocks in key metallogenic prospects -- typical deposits and geological characteristics of new discovered mineral geology -- law of uranium mineralization in basin -- prospecting method, prediction model and metallogenic prognosis.
    Abstract: This book introduces the geological background of sandstone-type uranium deposits in the Ordos Basin, Northwest China. Through comparative study of a large number of practical data such as uranium, coal and oil boreholes, the research system takes sedimentary basin as a unit and fully utilizes geological principles and test analysis to study the basic geological, geophysical, geochemical and remote sensing image characteristics of the basin, and to restores the favorable uranium-forming geological background brought by the change of the cognitive sedimentary environment conditions. It can be used as a reference for researchers, practitioners and as well as teachers and graduate students working in uranium deposit geology, sedimentary geology and related areas.
    Type of Medium: Online Resource
    Pages: XVIII, 405 p. 193 illus., 185 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811960284
    Series Statement: Springer Geology,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Physical geography. ; Environmental monitoring. ; Biotic communities. ; Geology. ; Environment. ; Freshwater ecology. ; Marine ecology. ; Earth System Sciences. ; Environmental Monitoring. ; Ecosystems. ; Geology. ; Environmental Sciences. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Introduction -- Freezing of lakes -- Structure and properties of lake ice -- Thermodynamics of Seasonal lake ice -- Mechanics of lake ice -- Proglacial lakes -- Lake Water Body in the Ice Season -- Ice-Covered Lakes Environment -- Lake ice Climatology -- Future of frozen lakes -- Annex: Ice Properties and Useful Formulae -- References -- Index.
    Abstract: This book updates the first edition for the status of knowledge in the physics of lake ice and the interactions between the ice cover and the liquid water underneath. Since the first edition was written in 2013, there has been a lot of progress in the field, in particular concerning environmental questions and the impact of climate change. Life conditions in ice-covered lakes and practical matters are now brought more into the picture so that the revision also properly serves as a handbook for applications. The author has worked widely with boreal lakes, polar lakes and Central Asian lakes that provides a wide geographical spectrum. Chapter 1 gives a brief overview and presents the research fields. The second chapter contains the classification of ice-covered lakes and observation techniques, especially remote sensing. In Chapter 3, the structure and properties of lake ice are presented including optics and geochemistry. Ice growth and melting are treated in Chapter 4, while the following chapter focuses on ice mechanics with applications to traffic on ice and ice loads. Chapter 6 goes into the exotic environment of pro-glacial lakes. Chapter 7 contains the stratification and circulation of the water body beneath lake ice, Chapter 8 presents the winter ecology of freezing lakes and discusses the lake ice interface toward the society, and Chapter 9 summarizes the climate change impact on lake ice seasons. The book ends into a brief closing chapter and list of references. Research problems for student learning are listed throughout the book. Annexes are included to provide numerical data of constants and standard formulae to help practical calculations and student tasks. Lake ice closely interacts with human living conditions, but people have learnt to live with that and to utilize the ice. In the present time this is true for on-ice traffic and recreation activities. Ice fishing has become a widely enjoyed hobby, and winter sports such as skiing, skating, and ice sailing are popular activities on frozen lakes. The lake ice response to eventual climate warming would appear as a shortening of the ice season due to the increasing air temperature and also as changing of the quality of the ice seasons via changes in ice thickness and structure. The book gives the whole story of lake ice into a single volume. The second, revised edition updates the content based on recent progress in winter limnology and ice physics research and applications. The author has contributed to lake ice research since the 1980s. In particular, his topics have been lake ice structure and thermodynamics, light transfer in ice and snow, ice mechanics in large lakes, and lake ice climatology. Mathematical modeling of ice growth, drift, and decay are covered in this research.
    Type of Medium: Online Resource
    Pages: XII, 361 p. 160 illus., 116 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031256059
    Series Statement: Springer Praxis Books
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Keywords: Neurosciences. ; Zoology. ; Neuropsychology. ; Neuroscience. ; Zoology. ; Neuropsychology.
    Description / Table of Contents: 1 The search for the nature of the soul -- 2 The functional neuroanatomy of the limbic system -- 3 Neuro- and psychopharmacology -- 4 Neurophysiology -- 5 Developmental neurobiology -- 6 Emotion, motivation, personality and their neurobiological foundations -- 7 Neurobiological consequences of early stress experiences -- 8 Psychological and neurobiological foundations of consciousness -- 9 Nature, diagnosis and classification of mental illness -- 10 Psyche and mental illness - addiction -- 11 Psychotic illness ("schizophrenia") -- 12 Affective disorders using the example of unipolar depression -- 13 Anxiety disorders -- 14 Neuropsychotherapy - psychotherapy methods and their effects -- 15 Psychoneuroscience and its significance for practice. .
    Abstract: The textbook builds a bridge between the "neurosciences" (theoretical and experimental neurobiology, neurology) and the "psychosciences" (psychology, psychiatry, psychotherapy) and aims to help provide the other disciplines with the most important and scientifically validated knowledge in an understandable form. The question of how mental experience and brain processes relate to each other has long been considered mysterious. In this book you will learn, based on the latest scientific findings, that the two areas form an indissoluble unity, even if we experience and study them differently. We present this unity in concrete terms in psychological-neurobiological theory and psychiatric-psychotherapeutic practice. We treat the principles of neurobiological excitation and information processing, the structure and function of the limbic system, the development of the personality and the interaction of genetic-epigenetic factors and prenatal and postnatal environmental influences, which may be favourable or unfavourable. On this basis, the exemplary presentation of important mental disorders such as addictive disorders, schizophrenic disorders, affective disorders and anxiety disorders takes place. Finally, following in the footsteps of the eminent psychotherapist Klaus Grawe, the concept of "neuropsychotherapy" is introduced and it is shown why psychiatry-psychotherapie and neurobiology belong together and can enrich each other. Our psychoneuroscientific approach paints a picture of man that is not based on opposites, but on an integration of psyche, brain, behavior and experience. The editors Prof. Dr. phil. Dr. rer. nat Gerhard Roth researches and teaches at the Institute for Brain Research, University of Bremen. "Psyche, personality and brain form an inseparable unit, even if we experience them differently". Prof. Dr. med. Dr. phil. Andreas Heinz is Clinic Director at the Department of Psychiatry and Psychotherapy at Charité Berlin. "The interplay of neurobiology, behavior and subjective experience is illuminated by new methods and models." Prof. Dr. med. Dr. phil. Henrik Walter heads the research area "Mind and Brain" at the Department of Psychiatry and Psychotherapy at Charité Berlin and is the deputy medical director of the clinic. "Neuroscience education in the practice of psychiatry and psychotherapy is increasingly becoming a matter of course - and that's a good thing." This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: XIV, 371 p. 61 illus., 57 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662657744
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Medical genetics. ; Bioinformatics. ; Neuroscience. ; Medical Genetics. ; Bioinformatics. ; Computational and Systems Biology.
    Description / Table of Contents: 1-Attitudes and smoking prevalence among undergraduate students in central Greece -- 2-Care of patients with Alzheimer’s disease -- 3-Regulation of antioxidant enzymes levels in rat brain -- 4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy -- 5-Cerebral critical closing pressure at concomitant traumatic brain injury -- 6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias -- 7-The Development of Antisense RNA Treatments using Engineered Protein Substrates -- 8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases -- 9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma -- 10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study -- 11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients -- 12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial -- 13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents -- 14-Stress system activation analysis in Greek female adolescents: a bioimpedance study -- 15-Kisspeptin and the genetic obesity interactome -- 16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis -- 17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia -- 18-Ebola virus disease and current therapeutic strategies; A review -- 19-Hyperbaric Oxygen Therapy effect on “Kinesia Paradoxa” Brain Circuits -- 20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line -- 21-Phospholipid Fatty Acid Profile of Spirulina platensis -- 22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study -- 23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives -- 24-Force spectroscopy in mechanical protein domains unfolding -- 25-Investigating the genetic component of Parkinson’s Disease -- 26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition -- 27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases -- 28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students -- 29-Synthesis, in silico stuiesand biological evaluation of 1, 3 ,4 oxadiazino indole derivatives -- 30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies -- 31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy -- 32-Microbes and the games they play -- 33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy -- 34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study -- 35-The effect of nutrients on Alzheimer’s disease biomarkers: A metabolomic approach -- 36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease -- 37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases -- 38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1 -- 39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome -- 40-Clinical and molecular study of common thrombophilia mutation prothrombin G20210A -- 41-Prenatal genetic testing for X-linked hypohidrotic ectodermal dysplasia -- 42-Preimplantation genetic testing for spastic paraplegia type 3 -- 43-Synthesis, anti-inflammatory activity and in-silico studies of some new 3-({P-DIMETHYLAMINO}BENZYLIDENE YDRAZINYLIDENE)-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES -- 44-Design, characterization and docking studies of some novel isatin derivatives for anticonvulsant and antidepressant activity -- 45-Skin mirrors Brain: A Chance for Alzheimer’s Disease Research -- 46-Mitochondrial homeostasis in neurodegeneration and ageing -- 47-The Alzheimer's Disease Chronicles: will evidence triumph over adversity? -- 48-Liposomes: Production Methods and Application in Alzheimer’s Disease -- 49-Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision -- 50-Biomarkers and Precision Medicine in Alzheimer’s Disease -- 51-The role of microRNAs in thrombosis -- 52-Photo-oxygenation: an innovative new therapeutic approach against amyloidoses.
    Abstract: The 5th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2022) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. This volume focuses on the sessions from the conference on Neuroscientific Advances.
    Type of Medium: Online Resource
    Pages: XXXI, 673 p. 58 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031319860
    Series Statement: Advances in Experimental Medicine and Biology, 1425
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurology . ; Nanowires. ; Neuropharmacology. ; Neuroscience. ; Neurology. ; Nanowires. ; Neuropharmacology.
    Description / Table of Contents: Section I: Neurodegenerative diseases -- Chapter 1: Nanowired delivery of cerebrolysin together with antibodies to amyloid beta peptide, phosphorylated tau and tumor necrosis factor alpha induces superior neuroprotection in Alzheimer's disease brain pathology exacerbated by sleep deprivation -- Chapter 2: Nanodelivery of histamine H3/H4 receptor modulators BF2649 and clobenpropit with antibodies to amyloid beta peptide in combination with alpha synuclein reduces brain pathology in Parkinson's disease -- Chapter 3: Co-administration of nanowired DL-3-n-butylphthalide (DL-NBP) together with mesenchymal stem cells, monoclonal antibodies to alpha synuclein and TDP-43 (TAR DNA-binding protein 43) enhance superior neuroprotection in Parkinson's disease following concussive head injury -- Chapter 4: Neuroprotective effects of nanowired delivery of cerebrolysin with mesenchymal stem cells and monoclonal antibodies to neuronal nitric oxide synthase in brain pathology following Alzheimer’s disease exacerbated by concussive head injury -- Section II: Central Nervous system Trauma -- Chapter 5: Co-administration of nanowired monoclonal antibodies to inducible nitric oxide synthase and tumor necrosis factor-alpha together with antioxidant H-290/51 reduces SiO2-nanoparticles induced exacerbation of pathophysiology of spinal cord trauma -- Chapter 6: Nanowired delivery of cerebrolysin with mesenchymal stem cells attenuates heat stress induced exacerbation of neuropathology following brain blast injury -- Chapter 7: Co-administration of nanowired oxiracetam and neprilysin with monoclonal antibodies to amyloid beta peptide and p-tau thwarted exacerbation of brain pathology in concussive head injury at hot environment -- Section III. Stress and Drugs of abuse -- Chapter 8: Nanowired delivery of mesenchymal stem cells with antioxidant compound H-290/51 reduces exacerbation of methamphetamine neurotoxicity in hot environment -- Chapter 9: TiO2-nanowired delivery of Chinese extract of Gingko biloba EGb-761 and bilobalide BN-52021 enhanced neuroprotective effects of cerebrolysin following spinal cord injury at cold environment -- Chapter 10: Nanowired delivery of curcumin attenuates methamphetamine neurotoxicity and elevates levels of dopamine and brain derived neurotrophic factor.
    Abstract: This book covers the use of nanomedicine in the delivery of neuroprotective agents, including pharmacological drugs, stem cells, neurotrophic factors, monoclonal antibodies and enzymes to induce greater beneficial effects in neurologic diseases. Thus, the main purpose of the book is to explore the delivery of drugs either alone or in combination with stem cells to enhance neuroprotection in neurological diseases. Brain pathology associated with acute trauma such as head injury and brain blast injury can also be managed using novel treatment strategies. In addition, emphasis is made that standard patterns of brain pathology may be complicated with multiple comorbidity factors where one agent alone is not sufficient to induce brain protection. Enzymes and antibodies may help in combination and enhance the efficacy when administered through nanotechnology. Progress in Nanomedicine in Neurologic Diseases will encourage further research in the field of neuroprotection, brain injury, neurodegenerative diseases, neuropharmacology, neuropathology, and neurology. Students and researchers along with policy makers, teachers and health care professionals may also benefit from the findings of the book for enhanced patients care.
    Type of Medium: Online Resource
    Pages: XV, 418 p. 40 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031329975
    Series Statement: Advances in Neurobiology, 32
    DDC: 612.8
    Language: English
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  • 45
    Keywords: Neurosciences. ; Developmental biology. ; Nervous system Diseases. ; Neuroscience. ; Developmental Biology and Stem Cells. ; Neurological Disorders.
    Description / Table of Contents: Chapter 1. History, origin and types of neurological disorders -- Chapter 2. Mechanistic approach involved in the progression of Neurodegenerative disorders -- Chapter 3. Isolation, characterization and differentiation of stem cells -- Chapter 4. Role of Stem cells as a protective agent against neurological complications -- Chapter 5. Mesenchymal stem cells and their application against neurodegenerative disorders -- Chapter 6. iPSCs and their role in amelioration of neurodegenerative disorders -- Chapter 7. Isolation, characterization and detailed history of exosomes derived from stem cells and their epigenetic biology -- Chapter 8. Stem cells vs exosomes: promising therapeutic approach and biomarkers agent against neurodegenerative disorders -- Chapter 9. Role of stem cells and derived exosomes as a novel therapeutic agent against neuroinflammation and stroke -- Chapter 10. Role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer’s and Parkinson's disease -- Chapter 11. Role of stem cells and derived exosomes and associated signalling molecules involved in neuroprotection -- Chapter 12. Exosome as nanoparticles against neurodegenerative disorders.
    Abstract: This book explores the therapeutic approaches of stem cells and stem cell-derived exosomes against neurodegenerative disorders (NDDs). The initial chapters introduce different neurodegenerative diseases and discuss the mechanistic aspects of their progression. The subsequent chapters cover strategies for the isolation, characterization, and differentiation of stem cells. In turn, the book reviews the protective role of stem cells against neurological disorders and examines regenerative approaches to treat neurological diseases using mesenchymal stem cells. The book also presents induced pluripotent stem cell (iPSC) technology for cellular therapy, drug screening, and in-vitro modeling of neurodegenerative diseases. Lastly, the book discusses the role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer's and Parkinson's disease and in associated signaling molecules involved in neuroprotection. This book is an invaluable source for researchers working towards understanding the potential of stem cell therapy in neurodegenerative disorders.
    Type of Medium: Online Resource
    Pages: XIII, 327 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938483
    DDC: 612.8
    Language: English
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  • 46
    Keywords: Neurosciences. ; Computational neuroscience. ; Biophysics. ; Science History. ; Neuroscience. ; Computational Neuroscience. ; Biophysics. ; History of Science.
    Description / Table of Contents: 1. Integrate and fire: RC circuits to model neurons and reward monkeys -- 2. Neuronal spike trains, stochastic point processes, and why George Gerstein’s papers are still worth reading -- 3. Visual Functions of Inferior Temporal Cortex -- 4. Early Days in the Gerstein Lab: Neuronal Plasticity in 1, 2, and 3 Dimensions -- 5. Patterns in Spike Trains -- 6. Introduction to the Gravity Papers -- 7. On correlations and interactions between neurons and with George Gerstein -- 8. Significance of Correlations between Spike Trains -- 9. Spatial-Temporal Spike Patterns -- 10. Does Cross Correlation Have a Unique Interpretation? -- 11. Neuronal Plasticity and my Experience Working with George L. Gerstein -- 12. Auditory Experiments and Modeling -- 13. Thinking about Analysis Methods with George in Philadelphia, Cambridge and Newcastle -- 14. Higher-order Correlations and Synfire Chains -- Nencki Award for George L. Gerstein.
    Abstract: This book brings together a selection of papers by George Gerstein, representing his long-term endeavor of making neuroscience into a more rigorous science inspired by physics, where he had his roots. Professor Gerstein was many years ahead of the field, consistently striving for quantitative analyses, mechanistic models, and conceptual clarity. In doing so, he pioneered Computational Neuroscience, many years before the term itself was born. The overarching goal of George Gerstein’s research was to understand the functional organization of neuronal networks in the brain. The editors of this book have compiled a selection of George Gerstein’s many seminal contributions to neuroscience--be they experimental, theoretical or computational--into a single, comprehensive volume .The aim is to provide readers with a fresh introduction of these various concepts in the original literature. The volume is organized in a series of chapters by subject, ordered in time, each one containing one or more of George Gerstein’s papers.
    Type of Medium: Online Resource
    Pages: XIII, 548 p. 253 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783030874476
    Series Statement: Springer Series in Computational Neuroscience,
    DDC: 612.8
    Language: English
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  • 47
    Keywords: Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Description / Table of Contents: Soundscape – The Development of a New Discipline -- Soundscape: A Construct of Human Perception -- Soundscape: The Holistic Understanding of Acoustic Environments -- Soundscape and Urban Planning -- Architectural Soundscapes: Theories, Methods, and Practice -- Psychoacoustics in Soundscape Research -- Measurements and Techniques in Soundscape Research -- Triangulation as a Tool in Soundscape Research -- Soundscape and Health -- Hospital Soundscape -- How to Put Soundscape into Practice.
    Abstract: The concept of “Soundscape” includes all sounds in an environment and focuses on the interrelationship between person, activity and place, both in space and time. The goal of this volume is to present and review the developments in the field of Soundscape, reflecting standardization procedures and diverse applications. Soundscape – The Development of a New Discipline Brigitte Schulte-Fortkamp, and André Fiebig Soundscape: A Construct of Human Perception André Fiebig Soundscape: The Holistic Understanding of Acoustic Environments Brigitte Schulte-Fortkamp and Pamela Jordan Soundscape and Urban Planning Bennett M. Brooks Architectural Soundscapes: Theories, Methods, and Practice Gary W. Siebein, and Keely M. Siebein Psychoacoustics in Soundscape Research Klaus Genuit, Brigitte Schulte-Fortkamp, and André Fiebig Measurements and Techniques in Soundscape Research Giovanni Brambilla, and André Fiebig Triangulation as a Tool in Soundscape Research Dick Botteldooren, Bert De Coensel, and Francesco Aletta, Jian Soundscape and Health Peter Lercher, and Angel M. Dzhambov Hospital Soundscapes Ilene Busch-Vishniac, and Erica Ryherd How to Put Soundscape into Practice André Fiebig, andBrigitte Schulte-Fortkamp .
    Type of Medium: Online Resource
    Pages: XVII, 330 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031227790
    Series Statement: Springer Handbook of Auditory Research, 76
    DDC: 612.8
    Language: English
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  • 48
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nervous system Diseases. ; Developmental neurobiology. ; Cognitive neuroscience. ; Neuroscience. ; Neurological Disorders. ; Development of the Nervous System. ; Cognitive Neuroscience.
    Description / Table of Contents: PART I. Iron, Brain Function and Behavior -- Chapter 1. Iron and Neuro-cognition -- Chapter 2. The Interplay Between Iron and Oxidative Stress in Brain Neurodegenerative Diseases -- Chapter 3. Specific Nutritional Therapeutic Approaches Targeting Iron Overload and Other Hallmarks of Brain Degenerative Diseases -- Chapter 4. Mediterranean Diet and Neuro-Cognition: Focus on Alzheimer disease -- PART II Brain disorders related to Iron -- Chapter 5. The Critical Roleplay of Iron Neurochemistry in Progression of Parkinson’s Disease -- Chapter 6. Iron-Calcium Crosstalk in Neurodegenerative Diseases -- Chapter 7. Iron and Alzheimer’s Disease -- Chapter 8. Iron and Multiple Sclerosis -- Chapter 9. Iron and Epilepsy -- Chapter 10. Iron and Subarachnoid Hemorrhage -- Chapter 11. Iron deficiency and psychiatric disorders -- Chapter 12. Iron and Neuro-developmental Disorders -- Chapter 13. Iron and Neuropathies.
    Abstract: This book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron deficiency. It presents the effect of iron dysregulation on neurophysiological mechanisms. The book provides an overview of iron metabolism and homeostasis at the cellular level and its regulation at the mRNA translation level. It emphasizes the importance of iron for brain development in fetal and early life in preterm infants. Further, it presents iron metabolism as a therapeutic target for novel pharmacological treatment against neurodevelopmental diseases and neurodegenerative disorders. It discusses the role of iron deficiency in sleep disorders and offers diagnosis and treatment of iron-related CNS diseases. Finally, it relates dysregulated expression of iron-related genes in brain tumors.
    Type of Medium: Online Resource
    Pages: XX, 280 p. 10 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811973277
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 49
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Cytology. ; Zoology. ; Neurology . ; Neuroscience. ; Cell Biology. ; Zoology. ; Neurology.
    Description / Table of Contents: The Architecture of the Presynaptic Release Site.-Cytomatrix Proteins in Presynaptic Terminal. - Multiple Modes of Fusion and Retrieval at the Calyx of Held Synapse -- Roles of SNARE Proteins in Synaptic Vesicle Fusion -- Calcium Sensors of Neurotransmitter Release. - Roles and Sources of Calcium in Synaptic Exocytosis -- Regulation of Presynaptic Calcium Channels -- Roles of mUnc13/UNC-13 and mUnc18/UNC-18 in Neurotransmitter Release. - The role of tomosyn in the regulation of neurotransmitter exocytosis. -Roles of complexins in Neurotransmitter Release. -Regulation of Neurotransmitter Release by AIPR-1/AIP and calstabins. - The Role of Potassium Channels in the Regulation of Neurotransmitter Release -- Roles of Neuropeptides in Synaptic Function. - Transsynaptic Regulation of Presynaptic Release Machinery in Central Synapses by Cell Adhesion Molecules. - Lipids and Secretory Vesicle Exocytosis -- Synaptic Vesicle Endocytosis.
    Abstract: Neurons communicate with each other by releasing neurotransmitters. This book provides comprehensive coverage of the molecular mechanisms involved in neurotransmitter release. The topics covered in the book range from the architecture and cytomatrix proteins of presynaptic sites, to the modes of synaptic vesicle exocytosis (full-collapse and kiss-and-run), and from the key molecules mediating synaptic vesicle fusion (SNAREs) to those that closely interact with them (UNC-13/Munc13, UNC-18/Munc18, tomosyn, and complexins). The book also delves into the calcium sensors of synaptic vesicle fusion (synaptotagmins and Doc2s), the sources of calcium that trigger synaptic exocytosis (voltage-gated calcium channels and ryanodine receptors), and the regulation of neurotransmitter release by potassium channels, cell adhesion molecules, lipids, aryl hydrocarbon receptor-interacting protein (AIP), presenilins, and calstabins. To aid in understanding and illustrate key concepts, the book includes sufficient background information and a wealth of illustrations and diagrams. The new edition includes major updates to previous chapters, as well as several new chapters that reflect the recent advances in the field. Comprehensive and cutting-edge, Molecular Mechanisms of Neurotransmitter Release, 2nd edition, is a valuable learning resource for neuroscience students and a solid reference for neuroscientists.
    Type of Medium: Online Resource
    Pages: XI, 401 p. 77 illus., 62 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031342295
    Series Statement: Advances in Neurobiology, 33
    DDC: 612.8
    Language: English
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  • 50
    Keywords: Neurosciences. ; Cytology. ; Ecology . ; Neural circuitry. ; Neuroscience. ; Cell Biology. ; Ecology. ; Neural Circuits.
    Description / Table of Contents: 1. Introduction -- 2. Diversity and evolution of jellyfish visual systems, Mollusks -- 3. Scallops distributed eyes -- 4. Chiton dispersed visual systems, Annelids -- 5. Errant polychaetes Arthropods -- 6. Spider eyes -- 7. Myriapod eyes -- 8. Insect ocelli -- 9. Batflies, copepods or larval stomatopods -- 10 -- Hyperiid amphipods, Echinoderms -- 11. Brittle star vision -- 12. Starfish vision.
    Abstract: This volume explores the diversity of distributed eyes and other unusual visual systems in nature. It compares the unique themes of optics, neural processing, and behavioral control that emerge from these visual systems with more-canonical eyes. This volume attempts to answer a number of questions about distributed visual systems. What are distributed visual systems good for, how do they function, and why have they arisen independently in so many phyla? Why are eye designs and visual system arrangements much more diverse in invertebrates? Each chapter includes an overview of the visual systems that exist in their group of animals, relates vision to ecology, and takes a comparative approach. .
    Type of Medium: Online Resource
    Pages: VII, 320 p. 70 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031232169
    Series Statement: Springer Series in Vision Research,
    DDC: 612.8
    Language: English
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  • 51
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: Editorial -- Dystonia in childhood - how insights from paediatric research enrich the network theory of dystonia -- Focal Dystonia and the Stress-Network -- Limbic influences in Musicians dystonia -- Network perspective on task-specific dystonia -- Electromyography as a method for distinguising dystonia-like behavior in mice -- Deep brain stimulation of the interposed cerebellar nuclei in a mouse model of dystonia -- Applications of Transcranial Magnetic Stimulation for understanding and treating dystonia -- Brain connectivity in dystonia: evidence from Magnetoencephalography -- Dysfunctional networks in functional dystonia -- Collicular-pulvinar-amygdala axis and adult-onset idiopathic focal dystonia syndrome -- Neuromodulation in dystonia -- Electrophysiological properties of pallidal cells in cervical dystonia patients undergoing unilateral DBS -- Clinical implications of dystonia as a neural network disorder.
    Abstract: A recently proposed novel scheme of dystonia suggests that it is a disorder of neural network. Impairment in any of the “nodes” of the network may result in deficient network activity, causing dystonia. This book aims to present various experimental evidence supporting the network theory of dystonia. Dystonia is the abnormal twisting and turning of the organ and associated involuntary oscillations. Although dystonia is less common than Parkinson’s disease, traumatic brain injury, or stroke, each of these common disorders present with dystonia. Information regarding the brain regions that may be involved in dystonia is surprisingly limited and often conflicting. With chapters written by subject matter experts, this is a unique title that focuses on dystonia as a network disorder. This book would be of interest to basic and clinical researchers with an interest in motor systems and movement disorders.
    Type of Medium: Online Resource
    Pages: XI, 242 p. 37 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031262203
    Series Statement: Advances in Neurobiology, 31
    DDC: 612.8
    Language: English
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  • 52
    Keywords: Neurosciences. ; Neurology . ; Nervous system Diseases. ; Cognitive neuroscience. ; Neurophysiology. ; Learning Physiological aspects. ; Memory Physiological aspects. ; Neuroscience. ; Neurology. ; Neurological Disorders. ; Cognitive Neuroscience. ; Neurophysiology. ; Learning and Memory.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer’s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer’s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer’s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".
    Abstract: This book highlights the key phases and central findings of Alzheimer’s Disease research since the introduction of the label ‘Alzheimer’s Disease’ in 1910. The author, Christian Behl, puts dementia research in the context of the respective zeitgeist and summarizes the paths that have led to the currently available Alzheimer’s drugs. As the reader is taken through the major developments in Alzheimer's Disease research, particularly over the past thirty years, Behl poses critical questions: Why are the exact causes of Alzheimer's Disease still in the dark, despite all the immense, worldwide research efforts in academia as well as in the pharmaceutical industry? Why has the majority of an entire research field kept focusing on a single hypothesis that establishes the deposition of the amyloid beta peptide in the brain as the key trigger of Alzheimer's pathology, even though this concept has still not been convincingly proven in the clinics? Are there other hypotheses that might explain the pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed? In this book, Behl tries to answer these questions. Starting with the historical background, the author illustrates the long and arduous research journey, its numerous setbacks, and the many alternative explanations for the disease, which have started gaining increasing attention and acceptance in the Alzheimer’s research community only more recently. With his deep dive into the history and progression of this research, including the most recent developments, Behl explains why he believes that it is high time to promote a paradigm shift in Alzheimer’s Disease research. The book is written for all researchers in the fields of neurobiology and neurodegeneration, as well as other biomedical fields, who would like to gain a broad and beyond the surface insight into (the key developments of) one of the most promoted research fields of our time. With its extensive literature references and over 100 illustrations, the book is also attractive for students and interested lay persons. Elaborating on all the different aspects and research approaches of this research field, the author aims to convince the reader that the underlying causes of Alzheimer’s Disease may be much more complex than previously thought and that this must be considered for future research directions. While he hopes that the Alzheimer’s research community is finally ready to shed its ‘amyloid-straitjacket’ that has hampered progress for too long, he is also convinced that a much-needed paradigm shift can guide future Alzheimer’s Disease research and provide a new and broader perspective on this age-dependent brain disease.
    Type of Medium: Online Resource
    Pages: XXV, 652 p. 116 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315701
    DDC: 612.8
    Language: English
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  • 53
    Keywords: Neurosciences. ; Immunology. ; Ophthalmology. ; Neuroscience. ; Immunology. ; Ophthalmology.
    Description / Table of Contents: High Resolution Imaging Mass Spectrometry of Human Donor Eye: Photoreceptor Cells and Basal Laminar Deposits of Age-related Macular Degeneration -- The non-canonical role of Complement Factor H in Retinal Pigment Epithelium (RPE) cells and implications for Age-related Macular Degeneration -- Macular Pigment Carotenoids and Bisretinoid A2E -- Disturbed matrix metalloproteinases activity in age-related macular degeneraton -- Current views on Chr10q26 contribuiton to age-related macular degeneration -- Untargeted lipidomic profiling of aged human retina with and without age-related macular degeneration (AMD) -- Decoding Race and Age-Relation Macular Degeneration: GPR 143 Activity is the Key -- Peroxisome proliferator-activated receptor gamma coactivator 1 alpha ( PGC-1x): a transcriptional regulator at the interface of aging and age-related macular degeneration? -- Regulation of ABCA1 by miR-33 and miR-34a in the aging eye -- The role of gene expression regulation on genetic risk of Age-related Macular Degeneration -- Elastin layer in Bruch's membrane as a target for immunizatio or tolerization to modulate patthology in the mouse model of somke-induced ocular injury -- Repuprosing drugs for treatment of age-relation macular degeneration -- Extracellular Vesicle RNA Contents as Biomarkers for Ocular Diseases -- Proteomics of retinal extracellular vesicles: a reviw inot an unexplored mechanism in retinal health and AMD pathogenesis -- Prime Editing Strategy to Instally the PRHP2 c.828+1G A mutations -- Analysis of CRB1 Pathogenic Variants Correctable with CRISPR Base and Prime Editing -- Generation of an Avian Myeloblastosis Virus (AMV) Reverse Transcriptase Prime Editor -- Pre-existing neutralizing antibodies against different adeno-associated virus serotypes in humans and large animal models for gene therapy -- Optimization of Capillary-based Western Blotting for MYO7A -- AAV Serotypes and Their Suitability for Retinal Gene Therapy -- Gene Augmentation ofautosomal dominant CRX-associated retinopathies -- Txnip gene therapy of retinitis pigmentosa improves cone health Factors affecting readthrough of natural versus premature termination codons -- Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease -- Network biology and medcine to resuce: Applications for retinal disease mechanisms and therapy -- Non-sydromic Retinal Degeneration Caused by Pathogenic Variants in Joubert Syndrome Genes -- Exonic variants that affect splicing- an opportunity for "hidden" mutations causing inherited retinal diseases -- Enhanced S-cone Syndrome, a Mini-Review -- The role of microglia in Inherited Retinal Diseases -- CD68: potential contributor to inflammation and RPE cell dystrophy -- Gene Expression of Clusterin, Tissue Inhibitor of Metalloproteinase-1, and Their receptors in Retinal Pigment Epithelial Cells and Muller Glial Cells is Modulated by Inflammatory Stresses -- Axonal Transport Defects in Retinal Ganglion Cells -- Connexins biology in the pathophysiology of retinal diseases -- Role of Nuclear NAD +in Retinal Homeostasis -- Retinal pigmented epithelium-derived ectopic norrin does not promote intraretinal angiogenesis in transgenic mice -- Caveolin-1 Muller glia exist as heat-resistant,high molecular weight complexes -- Role of VLC-PUFAs in Retinal and Macular Degeneration -- Ocular amyloid , condensates, and aggregates - higher order protein assemblies participate in both retinal degeneration and function -- Photoreceptor ion channels in signaling and disease -- The role of peripherin-2 /ROM1 complexes in photoreceptor outer segment disc morphogenesis -- Human mutations in Arl3, a small GTPase involved inlipidated cargo delibery to the cilia cause retinatl dystropthy -- Genotype-Phenotype Association in ABCA4-Associated Retinopathy -- Retinal pathoconnectomics: A Window into Neurodegeneration -- The role of Ceramide in Inherited Retinal Disease Pathology -- Extracelluar Matix: the Unexplored Aspects of Retinal Pathologies and Regeneration -- Role of TFEB in diseases assocaited with lysosomal dysfunction -- Retinoic acid receptor -related oprhan receptors (RORs) in eye development and disease -- A novel mouse model for Late-Onset Retinal Degeneration (L-ORD) devekios RPE abnormalities due to the loss of C1qtnf5/Ctrp5 -- Comparison of mouse models of autosomal dominant retinitis pigmentosa due to P23H muations of Rhodopsin -- Compensatory Cone-Mediated Mechanisms in Inherited Retinal Degeneration Mouse Models: A Functional and Gene Expression Analsyis -- Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Sress and Promotes ER Protein Degradation in Cyclic Nucleotide-gated Channel Deficiency -- Mouse choroid proteome revisited: foucs on aging -- Morphological and functional comparison of mice models for retinitis pigmentosa -- Current Advancements in Mouse Models of Retinal Disease -- Single-cell Itrnacriptomic Profiling of Muller Glia in the rd10 Retina -- Methods for in vivo characterization of proteostatis in the mouse retina -- Absence or PRCD leads to dysregulation in lipie Homeostatis resulting in disorganizationof photorecptor outer segment structure -- Expansion Microscopy of Mouse Photoreceptro Cilia -- Rod photorecptor specific ablation of Metformin target, AMPK, in preclinical model of autosomal recessvie retinitis pigmentosa -- TLR2 is highly overexpressed in retinal myeloid cells in the rd10 mouse model of retinitis pigmentosa -- Environmental light has an essentail effrect on the diseasae expression in a dominant RPE65 mutation -- Microglia Preserve Visual Function in A Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant -- Measuring the release of lactate from wild-type and rd1 mouse retina -- Aerobic glycolysis in photorecptors supports energy demand in the absence of mitochondrial coupling -- Redox Status in Retinitis Pigmentosa -- Perspectives on retinal dolichol metabolism and visual deficits in dolichol metalbolism-associated inherited disorders -- Retinal metabolic profile on IMPG2 deficiency mice with subretinal lesions -- Glutathione-coating of liposomes enhances the delivery of hydrophillic cargo to the inner nuclear layer in retinal cultures -- Modification of Mueller glial cell fate and proliferation with the use of small molecules -- A potential neuroprotective role for pyruvate kinase 2 in retinal degeneration -- Critical role of VEGF as a direct regulator of photorecptor function -- Lysine Ubiquitylation Drives Rhodopsin Protein Turnover -- In-silico prediction of MYO!C Rhodopsin Interactions and its Significance in Protein Localization and Visual Function -- A ciliary branched actin netowrk drives photoreceptor disc morphogenesis -- Revisiting the daily timing of POS phagocytosis -- Inhibition of Bacterial Peoptidoglycan Cytopahty by Retina Pigment Epithelial PGRP2 Amidase -- Understanding ischemic retinopathies: the role of Succinate and its recpto^T mutation -- Inducing neural regeneratio nfrom glia using proneural bHLH transcription factors.
    Abstract: This book contains the proceedings of the XIX International Symposium on Retinal Degeneration. A majority of those who spoke and presented posters at the meeting contributed to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium focused on the exciting new developments aimed at understanding these diseases and providing therapies for them. These retinal degeneration symposia are known by most as the “best” and “most important” meetings in the field. The volume presents representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy. We anticipate that the excitement of those working in the field and those afflicted with retinal degenerations is reflected in the volume.
    Type of Medium: Online Resource
    Pages: XIX, 588 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031276811
    Series Statement: Advances in Experimental Medicine and Biology, 1415
    DDC: 612.8
    Language: English
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  • 54
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Neurology . ; Cognitive psychology. ; Neuroscience. ; Neurology. ; Cognitive Psychology.
    Description / Table of Contents: The world of Brain: from Aging Brain, Diseased Brain to Social Brain -- Cognitive Aging:How the Brain Ages -- Cognitive Decline Associated with Aging -- The Overview of Cognitive Aging Model -- The Emotional and Affective Disorders in Cognitive Aging -- The Mechanism of Socioeconomic Status and Stress Effects on Cognition -- The Aging Patterns of Brain Structure, Function and Energy Metabolism -- Characteristics of Brain Network during Cognitive Aging -- Biomolecular Markers of Brain Aging -- Neurobiological Mechanisms of Cognitive Decline Caused by Brain Aging -- The Early Stage of Abnormal Aging: Cognitive Impairment -- The Terminal Stage of Abnormal Aging: Dementia -- The Effect of Cognitive Rehabilitation Training and Its Neuroimaging and Physiology Evidence -- Lifestyle Regulation and Its Evidence: Changes brought from Adjusting Correlative Factors of Cognitive Aging -- The Effect of Traditional Chinese Medicine on Delaying Age-related Cognitive Decline and Its Evidence.
    Abstract: This book reviews the research trends of cognitive aging and brain health from full-scale. It not only contains cognitive aging’s neurophysiological mechanism, clinical research and intervention measures, but also covers cognitive aging’s social psychological mechanism, such as the relation between old people’s motion, socioeconomic status and the cognitive aging. Through decades of research and practice, the views towards the cognitive aging process havebeen transferred from coping with cognitive decline to promoting cognitive ability. This book provides with the latest research findings and in-depth opinions of the cognitive aging and brain health, assisting researchers to grasp the theories, practice and trends of this field, and guide health-care workers to carry out the treatment and nursing for the aged.
    Type of Medium: Online Resource
    Pages: VIII, 194 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819916276
    Series Statement: Advances in Experimental Medicine and Biology, 1419
    DDC: 612.8
    Language: English
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  • 55
    Keywords: Neurosciences. ; Neurochemistry. ; Medicine Research. ; Biology Research. ; Regenerative medicine. ; Neuroscience. ; Neurochemistry. ; Biomedical Research. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: The Purinergic Signaling: Overview -- Adenosine A2A Receptor-containing Heteromers and Neuroprotection -- Purinergic Signaling in Brain Physiology -- Neurotrophic Actions of Adenosine and Guanosine: Implications for Neural Development and Regeneration? -- Purinergic Signaling in Neurogenesis and Neural Fate Determination: Current Knowledge and Future Challenges -- Purinergic Signaling in Autism Spectrum Disorder -- Purinergic Signaling in Depression -- Roles of Purinergic Receptors in Alzheimer's Disease -- Purinergic Signaling in Basal Ganglia Diseases: Parkinson's Disease -- A Step in the ALS Direction: Lessons from the Purinome -- Purinergic P2 Receptors in Epilepsy -- Purinergic Signaling in Neuroinflammation -- Purinergic Signaling in Brain Tumors -- Development of Purinergic Receptor Agonists and Antagonists -- Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation.
    Abstract: This volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson’s, and Alzheimer’s disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience.
    Type of Medium: Online Resource
    Pages: X, 376 p. 34 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031269455
    DDC: 612.8
    Language: English
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  • 56
    Keywords: Psychobiology. ; Human behavior. ; Cognitive neuroscience. ; Psychology, Experimental. ; Behavioral Neuroscience. ; Cognitive Neuroscience. ; Experimental Psychology.
    Description / Table of Contents: The promises and pitfalls of Virtual Reality -- Setting up your VR neuroscience laboratory -- Monitoring the autonomic system in VR -- Monitoring brain activity in VR: EEG and neuroimaging -- Eye-tracking and Pupillometry in VR -- VR for Movement and Action Science -- VR for Vision Science -- VR for Emotion -- VR for Thinking and Creativity -- VR for Social Cognition -- VR as a window into Consciousness -- Aging -- Learning -- Pain -- Cognitive and motor rehabilitation -- VR for Mental Health.
    Abstract: Virtual Reality (VR) is a rapidly maturing technology that offers new and unique solutions to otherwise intractable problems in the study of cognition, behavior and neuroscience. VR removes many of the constraints imposed by laboratory paradigms, allowing us to track cognitive, behavioral and brain responses to naturalistic (or even impossible) situations without sacrificing experimental control. But VR is not a tool that can be swiftly and effortlessly integrated into existing research pipelines; currently, the benefits of VR are accompanied by a host of methodological challenges and important practical considerations. To help navigate this new methodology, this volume provides a balanced review of both the exciting new findings emerging from VR labs and the challenges and limitations that are part and parcel of VR research. This volume is an important first step toward establishing a standardised methodology for conducting research in VR. To this end, the volume provides a wealth of practical advice for researchers who are new to the technology. This volume is authored by an interdisciplinary team of VR researchers including computer scientists, engineers, psychologists and neuroscientists. It highlights current research in the field to demonstrate how VR advances our understanding of the mind, while also providing groundbreaking solutions in applied domains.
    Type of Medium: Online Resource
    Pages: X, 387 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031429958
    Series Statement: Current Topics in Behavioral Neurosciences, 65
    DDC: 612.8
    Language: English
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    Keywords: Earth sciences. ; Geochemistry. ; Natural disasters. ; Geographic information systems. ; Human geography. ; Earth Sciences. ; Geochemistry. ; Natural Hazards. ; Geographical Information System. ; Human Geography.
    Description / Table of Contents: The Scientific Discovery of Merapi: From Ancient Javanese Sources to the 21st Century -- Physical Environment and Human Context at Merapi Volcano: A Complex Balance Between Accessing Livelihoods and Coping With Volcanic Hazards -- Merapi and Its Dynamic 'Disaster Culture' -- The Geodynamic Setting and Geological Context of Merapi Volcano in Central Java, Indonesia -- Crustal Structure and Ascent of Fluids and Melts Beneath Merapi: Insights From Geophysical Investigations -- Geological History, Chronology and Magmatic Evolution of Merapi -- The Godean Debris Avalanche Deposit From a Sector Collapse of Merapi Volcano.
    Abstract: This book provides the first comprehensive compilation of cutting-edge research on Merapi volcano on the island of Java, Indonesia, one of the most iconic volcanoes in the world. It integrates results from both the natural (geology, petrology, geochemistry, geophysics, physical volcanology) and social sciences, and provides state-of-the-art information on volcano monitoring, the assessment of volcanic hazards, and risk mitigation measures. As one of Indonesia’s most active and dangerous volcanoes, Merapi is perhaps best known for its pyroclastic density currents, which are produced by gravitational or explosive lava dome failures (commonly referred to as Merapi-type nuées ardentes). Merapi’s eruptions have posed a persistent threat to life, property and infrastructure within the densely populated areas on the volcano’s flanks, as demonstrated most recently by catastrophic eruptions, which attracted worldwide media interest.
    Type of Medium: Online Resource
    Pages: XIX, 572 p. 245 illus., 229 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031150401
    Series Statement: Active Volcanoes of the World,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Geophysics. ; Atmospheric science. ; Oceanography. ; Geotechnical engineering. ; Geophysics. ; Atmospheric Science. ; Ocean Sciences. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: 1. Mitigation of Rayleigh-Taylor Convection in a Porous Medium by Initial Periodic Fluctuations -- 2. Viscose mutual involvement of moving contacting liquids -- 3. The study of a drop collision with an obstacle -- 4. Methods of cavitation flows investigation -- 5. Modeling of a ring wave system source using satellite surveillance -- 6. Static form and quasi-stationary evaporation of groundwater in soil cracks and human biofluid between slides -- 7. Effect of barrier discharge plasma treatment on winter wheat seed germination -- 8. On the treatment of seeds with cold plasma to improve germination processes -- 9. Non-potential waves on the surface of stratified liquid -- 10. Scattering short hydroacoustics wave in the presence of long surface –waves -- 11. On the determination of diffuse reflectance of PTFE -- 12. Features of admixture dynamics in the fluid depth for complex vortex with free surface -- 13. Features of using perturbation theory to study convective diffusion -- 14. Stratification and segregation under laminar convection -- 15. Arctic air intrusions and changes in 7be fluxes from the atmosphere to the earth's surface -- 16. n Simulation of the Physical and Chemical Complex for Processing Hydrogen Sulfide in the Black sea region -- 17. Analysis of microbiological and sanitary-hygienic indicators of water from an underground source -- 18. Joint influence of Arctic ice dynamics and magnetic field diffusion on magnetohydrodynamic processes in geoenvironments -- 19. Approximation of the soil temperature by piecewise-continuous functions.
    Abstract: This book explains the dynamics of natural systems – the geosphere, hydrosphere and atmosphere – and their interactions, along with the human contribution to naturally occurring processes, which is one of the most urgent and practically important scientific problems of our age. The widespread use of sophisticated, tremendously powerful supercomputers now allows us to model complex phenomena that were previously inaccessible for analysis. Further, the introduction and advancement of a new generation of geophysical instruments – remote observing systems installed on ships, aircraft and satellites – make it possible to gather huge amounts of objective, representative data. The articles presented here offer valuable insights into the laboratory modelling of geo-environments and testing of newly developed physical and mathematical models.
    Type of Medium: Online Resource
    Pages: VI, 221 p. 114 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031230509
    Series Statement: Earth and Environmental Sciences Library,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Physical geography. ; Oceanography. ; Environment. ; Earth System Sciences. ; Earth System Sciences. ; Ocean Sciences. ; Earth System Sciences. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1. Symmetric and asymmetric tropics -- Chapter 2. Seasonal evolution of the monsoons -- Chapter 3. The coupled monsoons -- Chapter 4. Intraseasonal variations of the monsoon -- Chapter 5. The western pacific warm pool -- Chapter 6. The monsoons-ENSO teleconnection -- Chapter 7. ENSO -- Chapter 8. The inter-tropical convergence zone -- Chapter 9. Tropical atlantic variations -- Chapter 10. Large-scale aspects of extreme weather.
    Abstract: This upper-undergraduate/graduate-level textbook introduces students to large-scale tropical climate circulation and its variations, covering their fundamental aspects and our current understanding of how they are impacted in a warming world. From this volume, readers will gain an understanding of tropical climate variability from the meso- to planetary scale. Uniquely, equal emphasis is placed on atmospheric and oceanic processes of tropical phenomena. The book will appeal to senior undergraduate and graduate students across geoscience disciplines, including in meteorology, oceanography, geography, hydrology, and environmental science. .
    Type of Medium: Online Resource
    Pages: XVII, 309 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031128875
    Series Statement: Springer Atmospheric Sciences,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Earth sciences. ; Geotechnical engineering. ; Earth Sciences. ; Earth Sciences. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Planet Earth -- Crustal Processes and Materials -- Sedimentary Basins -- Sediments and Sedimentary Rocks -- Stratigraphy and Sedimentary Structures -- Depositional Environments and Facies -- The Petroleum System -- Exploration Methods -- Drilling and Logging -- Hydrocarbon Reserves and Quality -- Production Geology -- Unconventional Hydrocarbons Resources.
    Abstract: This book highlights the fundamental and applied aspects of geoscience that an engineer and geologist would need to be effective in the upstream petroleum industry. Geoscience is integral to exploration and production of petroleum, and a good understanding of the subject enables petroleum engineers to execute their tasks effectively in an interdisciplinary and collaborative environment. Most petroleum engineers lack a geological perspective, owing to their increased focus on core engineering disciplines, and evaluate rocks from a mechanical object. At the same time, books in geoscience which are currently available for undergraduate education are written for educating geologists only. This book aims to provide geoscience fundamentals as required by engineers and geologists to prepare for a career in the upstream petroleum industry.
    Type of Medium: Online Resource
    Pages: XXV, 192 p. 115 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811976407
    DDC: 550
    Language: English
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    Keywords: Earth sciences. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Electric power distribution. ; Earth Sciences. ; Fossil Fuel. ; Energy Grids and Networks.
    Description / Table of Contents: Introduction -- Mechanisms and processes of petroleum migration -- Carrier systems and their characterization -- Efficiencies of migration and accumulation and resources assessing -- Case study: dynamic study on petroleum migration and accumulation in the Dongying Depression, Bohaiba Basin.
    Abstract: This book presents the authors' research findings on the dynamics of oil migration, research methodologies, insights and applications in petroliferous basins. It studies the behaviors of oil migration in porous media through physical experiments and numerical simulations, explores the mechanism of oil migration and effects of migration process, and then establishes a migration modeling method by coupling the source, driving forces and carriers. The new method can be used to estimate the amount of migrated hydrocarbons and then predict the location of possible hydrocarbon accumulations in different parts of a basin. This approach is useful for resources assessment and prediction of the distribution of hydrocarbon accumulations. An example utilizing this methodology is presented to study the dynamics of migration and accumulation processes in the southern slope of Dongying Depression in Bohai Bay Basin in China. The book appeals to scientists and professionals working on petroleum prospecting as well as faculty and students in petroleum geology.
    Type of Medium: Online Resource
    Pages: VIII, 390 p. 192 illus., 158 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811955341
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Earth sciences. ; Biogeography. ; Architecture. ; Geochemistry. ; Geotechnical engineering. ; Earth Sciences. ; Biogeosciences. ; Architecture. ; Geochemistry. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Saint Petersburg - the city of stone -- Saint Petersburg - the stones city -- The Bronze Horseman and Thunder Stone - the symbol of St. Petersburg -- Peter and Paul Cathedral – the beginning of St. Petersburg -- Alexander Column - the world's largest monolith -- Natural stone in the modern St. Petersburg -- Part II. Historical quarries of natural stone -- History of stone quarrying in Virolahti area -- Serdobolsky granites from Lake Ladoga -- Granite necklace of the Karelian Isthmus -- Ruskeala marble - joyful stone of Karelia -- Part III. Natural stone in the history of two cultures -- Saimaa Canal - the history of the sea route -- Stones of Valaam and Novovalaam monasteries -- Natural Stone in church buildings -- Towns-fortresses (Vyborg, Korela) -- Dragon's Teeth - Mannerheim defense lines -- Life and Stone (bridges, roads, dwellings, basements). .
    Abstract: The book introduces readers to the heritage of St. Petersburg, sharing the geological history of a unique city, a world heritage site, and part of the UNESCO list. It also explains the role of small towns and fortresses near St. Petersburg, whose stone decoration played an essential role in the city’s evolution and was key in the history of neighboring cultures. The book also describes the main architectural symbols of St. Petersburg, such as the Alexander Column, the Bronze Horseman, the Peter and Paul Fortress and more. In addition to five guided tours of the city center, it offers descriptions of historic quarries, some of which are now open-air museums.
    Type of Medium: Online Resource
    Pages: X, 223 p. 278 illus., 249 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031188619
    Series Statement: Geoheritage, Geoparks and Geotourism, Conservation and Management Series,
    DDC: 550
    Language: English
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    Keywords: Earth sciences. ; Geographic information systems. ; Natural disasters. ; Geology. ; Environmental monitoring. ; Earth Sciences. ; Geographical Information System. ; Natural Hazards. ; Geology. ; Environmental Monitoring.
    Description / Table of Contents: Modern Methods of Rock Mass Characterisation and Rock Fall Monitoring: A Review -- Rock Mass Characterization and Rockfall Monitoring: Traditional Approaches -- Criteria of the Prehistoric Rock Avalanches Identification and Discrimination -- Stability Assessment of Markundi Hills Using Q-slope, SMR and Simulation Tools -- Geotechnical Investigation of Landslide in Ooty, India -- Geomechanical and Kinematic Stability Analysis of Unstable Slopes (near 9th km stone) on Palani – Kodaikkanal Ghat Section in Tamil Nadu -- Geological and Geotechnical Studies of Nungkao Landslide along Imphal-Jiribam National Highway, NH-37, Manipur, India -- Stability Assessment of Lateritic Soil Slope along NH-66, Ratnagiri Maharashtra, India -- Rockfall Hazard: A Comprehensive Review of Current Mitigation Practices -- Debris Flow Hazard in India: Current Status, Research Trends, and Emerging Challenges -- Early Warning System for Rainfall Induced Landslide – A Laboratory Prototype Model -- Study and Instrumental Monitoring of Landslides at the "Russkie Gorki" Site in the Mzymta River Valley, Sochi Region, Russia -- Application of Scoops3D and GIS for Assessing Landslide Hazard in Trung Chai Commune, Sapa, Vietnam -- Landslide Susceptibility Assessment using Frequency Ratio Model in Turung Mamring, South District of Sikkim, India -- Mapping of Annual Ground Displacement using Remote Sensing Methods for Critical Slopes along the Bhagirathi River in Uttarakhand, India -- Landslides Inventory of Active Ramgarh Thrust Zone through Image Processing and GIS Techniques in Sikkim, India -- Landslide Susceptibility Zonation Mapping using Frequency Ratio, Information Value Model, and Logistic Regression Model: A Case Study of Kohima District in Nagaland, India -- Unmanned Aerial Vehicles Technology for Slope Hazard Assessment, Monitoring, and Post Failure Management -- Landslide Hazard Assessment Using Machine Learning and GIS -- Social and Economic Impacts of Kotropi Landslide on National Highways of Himalayas – A Case Study. .
    Abstract: This book intends to decipher the knowledge in the advancement of understanding, detecting, predicting, and monitoring landslides. The number of massive landslides and the damages they cause has increased across the globe in recent times. It is one of the most devastating natural hazards that cause widespread damage to habitat on a local, regional, and global scale. International experts provide their experience in landslide research and practice to help stakeholders mitigate and predict potential landslides. The book comprises chapters on: Dynamics, mechanisms, and processes of landslides; Geological, geotechnical, hydrological, and geophysical modelling for landslides; Mapping and assessment of hazard, vulnerability, and risk associated with landslides; Monitoring and early warning of landslides; Application of remote sensing and GIS techniques in monitoring and assessment of landslides. The book will be of interest to researchers, practitioners, and decision-makers in adapting suitable modern techniques for landslide study.
    Type of Medium: Online Resource
    Pages: XXV, 419 p. 166 illus., 157 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031238598
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Geophysics. ; Engineering mathematics. ; Oceanography. ; Geophysics. ; Engineering Mathematics. ; Ocean Sciences.
    Description / Table of Contents: Vortex flow in a homogeneous fluid -- Solute admixture transport from a compact source in a composite vortex -- Transfer of immiscible admixture in a vortex flow -- Motion of solid markers in a vortex flow -- Modelling hydrocarbon spillage on the surface of water.
    Abstract: The study of vortex and wave flows is one of the traditional problems of fluid mechanics, the practical importance of which has grown significantly in recent years. Consideration of the processes of substance transfer in such complex systems as natural water bodies is fraught with many difficulties of a methodological and fundamental nature: the extreme complexity of conducting a full-scale experiment, the complexity and variability of hydrophysical fields of the ocean and hydrometeorological conditions during research, and also, in some cases, the complexity and the variability of the properties of the transferred substance. In this connection, it is of particular interest to study the transfer of markers in stationary vortex and wave flows, which can form in laboratory facilities with constant external conditions. In this case, it is possible to avoid problems associated with the spatial and temporal variability of natural sources of vortex formations and directly trace the dependence of the characteristic flow parameters or the characteristics of the movement of solid or other objects placed during. This book presents the results of experimental and theoretical studies of the dynamics and structure of multiphase vortex flows and the nature of the transfer of three types of markers: solid-state (ice, plastic), immiscible with water (oil, oil, diesel) and soluble (aniline dyes, uranyl). The results will be important, first of all, for a better understanding of the behavior of various impurities in the circulation flows and more accurate prediction of their distribution in natural conditions (in a stratified hydrosphere and atmosphere).
    Type of Medium: Online Resource
    Pages: XIV, 145 p. 92 illus., 75 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031318566
    Series Statement: Earth and Environmental Sciences Library,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Earth sciences. ; Cultural property. ; Archaeology. ; Paleontology . ; Sedimentology. ; Earth Sciences. ; Archaeology and Heritage. ; Paleontology. ; Sedimentology.
    Description / Table of Contents: Part1. Introduction -- Chapter1. Geoheritage: A growing research topic in morocco and the middle atlas -- Part2. lithostratigraphic and sedimentological heritage -- Chapter2. Paleozoic-lower and middle lias lithostratigraphic and sedimentological geosites of the middle atlas (morocco): inventory and valorization -- Chapter3. The brown and ammonitic-rosso levels: geoheritage reflecting the toarcian lithostratigraphy of the middle atlas (morocco) -- Chapter4. Jbel serhla: A particular geosite of lithostratigraphic, paleogeographic and paleontological amplitude -- Chapter5. Cenozoic sites of the middle atlas (morocco): an alpine heritage to be preserved -- Part3. Palaeontological heritage -- Chapter6. The palaeontological heritage of vertebrates in the middle atlas (morocco): initiatives of inventory and assessment for a rare heritage threatened with degradation -- Chapter7. 3D virtual visit of the paleontological site of anchrif (middle atlas, morocco): a new perspective for the enhancement of geoheritage -- Part4. Hydric heritage -- Chapter8. Hydric geosites of middle atlas: a natural heritage under threat -- Chapter9. Fluvial heritage of the middle atlas (morocco): an essential element for regional sustainable development -- Part5. Karst heritage -- Chapter10. Exo- and endokarst of the middle atlas (morocco): from inventory to promotion -- Chapter11. Geomorphological study of the endo-karst of the middle atlas as a geological heritage to be preserved, case of the chaara cave, province of taza -- Chapter12. Biodiversity endokarstic of the middle atlas: an underground richness to inventory -- Part6. Volcanic heritage -- Chapter13. Volcanic landscape of the middle atlas: a representative heritage of moroccan geological history -- Chapter14. The volcanism of the plio-quaternary of azrou-timahdite plateau (central middle atlas, morocco): potential for geotourism development -- Part7. Conclusion -- Chapter15. Geoheritage: between geological heritage protection initiatives.
    Abstract: This book is a condensed summary of a broad spectrum of the geological heritage of the Middle Atlas. It has the particularity of proposing an in-depth synthesis and a critical review of the geoheritage of the region. The book addresses the issues related to geoheritage and methodologies for the selection, inventory, assessment and preservation of geosites. It reviews the state of the art of geoheritage in Morocco, particularly in the Middle Atlas, in order to identify geosites with rare and unique geological features. The book presents a detailed study of lithostratigraphic and sedimentological heritage as geosites witnessing at different spatial and temporal scales the evolution and the stratigraphic, sedimentological and paleogeographic history of the Middle Atlas range. It also presents the paleontological heritage of vertebrates by reviewing the discoveries of paleontological sites and their risks in order to present its conservation plans. It also addresses the hydric and fluvial heritage by presenting the potential of water resources and the impact of climate change on the latter. Furthermore, it highlights the karst heritage by exposing an inventory of exo- and endokarst geosites in order to emphasize some unique sites on a national and African scale as well as revealing the underground biodiversity related to this heritage. Finally, it proposes a presentation of the volcanic heritage in order to assess the volcanic geosites that testify to the strombolian, phreatomagmatic and Hawaiian dynamism of the region. The book is mainly intended for researchers, geologists and specialists of the Moroccan Middle Atlas region wishing to acquire a broad multidisciplinary or even transdisciplinary knowledge. It will also be accessible to a non-initiated public, interested in the richness of the Moroccan geoheritage, as well as to Moroccan territorial authorities (High Commission for Water and Forests, Ministry of Tourism, National Institute of Archaeology and Heritage Sciences, etc.) who can benefit from it in the perspective of their strategies of preservation of the national geological heritage. This work will be an example for geoscientists, on an African scale, of a valorization of territorial geological heritage.
    Type of Medium: Online Resource
    Pages: XV, 240 p. 166 illus., 161 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031270734
    Series Statement: Geoheritage, Geoparks and Geotourism, Conservation and Management Series,
    DDC: 550
    Language: English
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    Keywords: Geophysics. ; Geography Mathematics. ; System theory. ; Geophysics. ; Mathematics of Planet Earth. ; Complex Systems.
    Description / Table of Contents: 1. The order parameter fluctuations of seismicity are minimized before major earthquakes -- 2. A straightforward experimental fact demonstrating the physical interconnection of a SES activity with seismicity -- 3. The spatiotemporal variations of the minimum of the seismicity order parameter fluctuations may estimate the epicenter of an impending major earthquake -- 4. Temporal correlations in the magnitude time series before and after the minimum of the order parameter fluctuations of seismicity -- 5. Identifying the occurrence time of a mainshock by means of the minimum of the seismicity order parameter fluctuations -- 6. On a unique increase of the seismicity order parameter fluctuations before the ����9 Tohoku earthquake in Japan in 2011 -- 7. Minimum of the seismicity entropy change under time reversal before major earthquakes in natural time analysis -- 8. Fluctuations of the entropy change of seismicity under time reversal before major earthquakes in natural time analysis -- 9. Identifying the occurrence time of a mainshock by means of the fluctuations of the seismicity entropy change under time reversal -- 10. Compatibility of the SES generation model with the precursory phenomena before the Tohoku ����9 earthquake in Japan in 2011 -- 11. Recent advances on the estimation of a future earthquake epicenter based on natural time -- 12. Study of the global seismicity using natural time analysis -- 13. Applications of natural time analysis to disaster prediction in other disciplines. .
    Abstract: This monograph contains the advances achieved based on the content of our previous monograph published in 2011. In other words, the present monograph can be considered as "Part II" containing new results accomplished in the last decade. These were published in several reputed international journals based on the concept of natural time discussed in detail in our earlier monograph. The analysis in natural time enables the study of the dynamical evolution of a complex system and identifieswhen the system enters a critical stage. A wide range of applications are discussed, such as the cases of environmental extreme events-disasters and sudden cardiac death. More light is shed on changes of natural time features before major earthquakes like the 2011 M9 Tohoku earthquake in Japan and the 2017 M8.2 Chiapas earthquake in Mexico. Hence, natural time analysis plays a key role in predicting impending catastrophic events in general with a primary audienceResearchers and Academics in Physics, Earth Sciences, and Medicine.
    Type of Medium: Online Resource
    Pages: XXIII, 361 p. 178 illus., 172 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031260063
    DDC: 550
    Language: English
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    Keywords: Earth sciences. ; Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Geochemistry. ; Environment. ; Earth Sciences. ; Water. ; Freshwater and Marine Ecology. ; Geochemistry. ; Environmental Sciences. ; Earth Sciences.
    Description / Table of Contents: From the Contents: History of research on the geology and biology of the Kenya Rift lakes -- Geology of the Kenya Rift Valley -- Environmental setting of the Kenya Rift Valley -- Limnology and sedimentology of tropical lakes – a short introduction -- The Northern Kenya Rift -- The Central Kenya Rift -- Lake Victoria -- The Southern Kenya - Northern Tanzania Rift -- Small lakes and wetlands of the Kenya Rift.
    Abstract: This book is the first comprehensive account of the modern Kenya Rift Valley lakes and their precursor lakes preserved in the sedimentary record. The first part gives the broad geological and environmental background to the Kenya Rift and a history of research. In the second part, each modern lake is described from perspectives of geology, limnology, ecology, sedimentology and late Quaternary history. The fossil lake sediments, some linked to hominin sites, and their paleoenvironmental history are considered in the third part. In the fourth section, the global tectonic, volcanic and climate controls of lake evolution in continental rifts are examined. The last section discusses the resource potential of the lakes and their sediments, and the environmental issues that currently affect the modern lakes. This research-level book (geology, paleoecology) is illustrated throughout by original figures and photographs.
    Type of Medium: Online Resource
    Pages: XXVI, 977 p. 375 illus., 367 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783642250552
    Series Statement: Syntheses in Limnogeology,
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Keywords: Earth sciences. ; Geotechnical engineering. ; Materials Analysis. ; Mineralogy. ; Geography. ; Earth Sciences. ; Geotechnical Engineering and Applied Earth Sciences. ; Characterization and Analytical Technique. ; Mineralogy. ; Earth and Environmental Sciences.
    Description / Table of Contents: Introduction -- Materials -- Mineral Raw Materials -- Ceramics -- Glass -- Building Materials -- Refractory Materials -- Electronics -- Hard Materials -- Crystal Growth -- Energy -- Environmental Mineralogy -- Biomineralogy -- Steel.
    Abstract: This textbook teaches important material and technological fundamentals in various technical systems and applied geoscientific fields. Beginning with the mineralogical characteristics of selected non-metallic raw materials and industrial minerals, this book presents the connections between properties and industrial applications and discusses the environment-relevant aspects as well as problems of biomineralogy. An introduction is given to important mineralogical and physico-chemical aspects of ceramic materials such as silicate ceramics, glass, cement, refractory materials as well as an overview about material synthesis. This makes it the first textbook to present the fundamentals of applied mineralogy as a material-related geoscience in a compact form and to show important bridges to industrial issues and approaches to solutions. It is aimed primarily at undergraduate students of geosciences and materials science, but is also suitable for related disciplines and practical applications. The authors Prof. Dr. Jens Götze and Prof. Dr. Matthias Göbbels, teach and research in the field of applied mineralogy at the Institute of Mineralogy of the TU Bergakademie Freiberg, Germany and at the Chair of Mineralogy of the Friedrich-Alexander University Nuremberg-Erlangen, Germany, respectively, and have had intensive industrial contacts and cooperation for many years. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: IX, 266 p. 214 illus., 83 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662648674
    DDC: 550
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Earth sciences. ; Machine learning. ; Artificial intelligence. ; Mathematics. ; Application software. ; Earth Sciences. ; Machine Learning. ; Artificial Intelligence. ; Applications of Mathematics. ; Computer and Information Systems Applications.
    Description / Table of Contents: Part 1: Basic Concepts of Machine Learning for Earth Scientists -- Chapter 1. Introduction to Machine Learning -- Chapter 2. Setting Up your Python Environments for Machine Learning -- Chapter 3. Machine Learning Workflow -- Part 2: Unsupervised Learning -- Chapter 4. Unsupervised Machine Learning Methods -- Chapter 5. Clustering and Dimensionality Reduction in Petrology -- Chapter 6. Clustering of Multi-Spectral Data -- Part 3: Supervised Learning -- Chapter 7. Supervised Machine Learning Methods -- Chapter 8. Classification of Well Log Data Facies by Machine Learning -- Chapter 9. Machine Learning Regression in Petrology -- Part 4: Scaling Machine Learning Models -- Chapter 10. Parallel Computing and Scaling with Dask -- Chapter 11. Scale Your Models in the Cloud -- Part 5: Next Step: Deep Learning -- Chapter 12. Introduction to Deep Learning.
    Abstract: This textbook introduces the reader to Machine Learning (ML) applications in Earth Sciences. In detail, it starts by describing the basics of machine learning and its potentials in Earth Sciences to solve geological problems. It describes the main Python tools devoted to ML, the typical workflow of ML applications in Earth Sciences, and proceeds with reporting how ML algorithms work. The book provides many examples of ML application to Earth Sciences problems in many fields, such as the clustering and dimensionality reduction in petro-volcanological studies, the clustering of multi-spectral data, well-log data facies classification, and machine learning regression in petrology. Also, the book introduces the basics of parallel computing and how to scale ML models in the cloud. The book is devoted to Earth Scientists, at any level, from students to academics and professionals.
    Type of Medium: Online Resource
    Pages: XVI, 209 p. 102 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031351143
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 550
    Language: English
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    Keywords: Physical geography. ; Geology. ; Atmospheric science. ; Geochemistry. ; Earth System Sciences. ; Geology. ; Atmospheric Science. ; Geochemistry.
    Description / Table of Contents: Section 1. Hydrology, Hydrogeology, Hydrogeochemistry and Water Resources -- Section 2. Biogeochemistry, Geobiology and Geoecology -- Section 3. Atmospheric Sciences, Meteorology, Climatology, Oceanography.
    Abstract: This edited book is based on the accepted papers for presentation at the 1st MedGU Annual Meeting, Istanbul 2021. With three sections spanning a large spectrum of geological and geoenvironmental topics, this book presents a series of newest research studies that are nowadays relevant to Middle East, Mediterranean region, and Africa. The book includes major subjects related to hydrogeology, geoecology, and atmospheric sciences. Case studies are from the fields of hydrology, hydrogeology, hydrogeochemistry and water resources, biogeochemistry, geobiology and geoecology, atmospheric sciences, meteorology, climatology, and oceanography.
    Type of Medium: Online Resource
    Pages: XXX, 293 p. 181 illus., 171 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031431692
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 550
    Language: English
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  • 71
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geophysics. ; Geology. ; Geotechnical engineering. ; Power resources. ; Geophysics. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Introduction to inversion theory -- Elements of probability theory -- Vector spaces of models and data -- Principles of regularization theory -- Linear inverse problems -- Probabilistic methods of inverse problem solution -- Gradient-type methods of non-linear inversion -- Joint inversion based on analytical and statistical relationships between different physical properties -- Joint inversion based on structural similarities -- Joint focusing inversion of multiphysics data -- Joint minimum entropy inversion -- Gramian method of generalized joint inversion -- Probabilistic approach to gramian inversion -- Simultaneous processing and fusion of multiphysics data and images -- Machine learning in the context of inversion theory -- Machine learning inversion of multiphysics data -- Modeling and inversion of potential field data -- Case histories of joint inversion of gravity and magnetic data. .
    Abstract: Different physical or geophysical methods provide information about distinctive physical properties of the objects, e.g., rock formations and mineralization. In many cases, this information is mutually complementary, which makes it natural for consideration in a joint inversion of the multiphysics data. Inversion of the observed data for a particular experiment is subject to considerable uncertainty and ambiguity. One productive approach to reducing uncertainty is to invert several types of data jointly. Nonuniqueness can also be reduced by incorporating additional information derived from available a priori knowledge about the target to reduce the search space for the solution. This additional information can be incorporated in the form of a joint inversion of multiphysics data. Generally established joint inversion methods, however, are inadequate for incorporating typical physical or geological complexity. For example, analytic, empirical, or statistical correlations between different physical properties may exist for only part of the model, and their specific form may be unknown. Features or structures that are present in the data of one physical method may not be present in the data generated by another physical method or may not be equally resolvable. This book presents and illustrates several advanced, new approaches to joint inversion and data fusion, which do not require a priori knowledge of specific empirical or statistical relationships between the different model parameters or their attributes. These approaches include the following novel methods, among others: 1) the Gramian method, which enforces the correlation between different parameters; 2) joint total variation functional or joint focusing stabilizers, e.g., minimum support and minimum gradient support constraints; 3) data fusion employing a joint minimum entropy stabilizer, which yields the simplest multiphysics solution that fits the multi-modal data. In addition, the book describes the principles of using artificial intelligence (AI) in solving multiphysics inverse problems. The book also presents in detail both the mathematical principles of these advanced approaches to joint inversion of multiphysics data and successful case histories of regional-scale and deposit-scale geophysical studies to illustrate their indicated advantages.
    Type of Medium: Online Resource
    Pages: XVI, 369 p. 52 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819967223
    Series Statement: Advances in Geological Science,
    DDC: 550
    Language: English
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  • 72
    Keywords: Earth sciences. ; Evolution (Biology). ; Earth Sciences. ; Evolutionary Biology.
    Description / Table of Contents: 1 Introduction -- 2 Palaeogeographical settings of South China in the Changhsingian to Induan and palaeogeographic distribution of the studied Permian Triassic Boundary sections -- 3 Description of the studied Permian Triassic Boundary sections of South China -- 4 Age analysis and correlation -- 5 Temporal and spatial processes and dynamics of the Permian Triassic Boundary mass extinction (PTBME) in South China.
    Abstract: This book timely provides high-quality records of 32 PTB sections across different depositional settings from terrestrial to marine facies in South China, including descriptions of lithologies, high-resolution correlation of key boundaries and fossil occurrences at each section. This book also analyzes the patterns and processes of the community and ecosystem evolution over space and through time in the lead to the end-Permian mass extinction, and critically analyzes the mostly debated hypothesis, anoxia and volcanism, which were considered as the causes of mass extinction, based on the data from the studied sections of South China, together with materials from other regions of the world.
    Type of Medium: Online Resource
    Pages: XII, 287 p. 98 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819993505
    Series Statement: New Records of the Great Dying in South China,
    DDC: 550
    Language: English
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  • 73
    Keywords: Earth sciences. ; Philosophy. ; Archaeology. ; Earth Sciences. ; Philosophy. ; Archaeology.
    Description / Table of Contents: Chapter 1. Introduction to the Book “Bridges to global ethics” (Giuseppe Di Capua) -- Chapter 2. Geoethics for Redefining Human-Earth System Nexus (Silvia Peppoloni) -- Chapter 3. The Sustainable and the Unsustainable: What Is a Habitable Planet? (Tanella Boni) -- Chapter 4. Geology and Knowledge Culture (Robert Frodeman) -- Chapter 5. The Ethics of Gaia: Geoethics From an Evolutionary Perspective (Sofia Belardinelli) -- Chapter 6. Materialities, Perceptions and Ethics (Harold P. Sjursen) -- Chapter 7. Affirmative Ethics, New Materialism and the Posthuman Convergence (Rosi Braidotti) -- Chapter 8. Epilogue (Torbjörn Lodén).
    Abstract: This book contributes to the current discussion on geoethics and global ethics within the geoscience and humanities communities. It provides new content and insights into developing convergent human actions in response to global anthropogenic changes, based on perspectives that make it possible to combine geoscience knowledge with humanities and social sciences approaches. Selected authors present their reflections, findings and insights regarding the vision of geoethics (ethics of responsibility towards the Earth) as global ethics from philosophical, humanities and social sciences perspectives. In addition, they discuss ethical frameworks from diverse cultural traditions, searching for points of intersection with geoethics. The goal: for global environmental problems to be managed via multi-perspective approaches that can more effectively accommodate complexity. Combining the strengths of the geosciences, humanities and social sciences can pave the way for a paradigm shift in how human societies develop adaptive, sustainable responses to environmental changes and societal inequalities.
    Type of Medium: Online Resource
    Pages: VII, 115 p. 4 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031222238
    Series Statement: SpringerBriefs in Geoethics,
    DDC: 550
    Language: English
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  • 74
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Earth sciences. ; Climatology. ; Sedimentology. ; Water. ; Hydrology. ; Earth Sciences. ; Climate Sciences. ; Sedimentology. ; Water.
    Description / Table of Contents: Chapter 1-Lake sediments and climate studies -- Chapter 2- Working approach: Field investigation -- Chapter 3- Working approach: Lab investigation and proxy development -- Chapter 4- Proxy response in various climatic conditions -- Chapter 5- Summary and Future scope.
    Abstract: The book discusses a comprehensive overview of various limnological approaches for climate studies, and sheds light on a multi-dimensional approach (i.e., field, laboratory, and data analysis; modern investigations; proxy development/calibration; proxy interpretation; and validation of climate models with proxy data) for climate reconstruction. The study highlighted the utilization of lake sediment as an archive for paleoclimate research. With the help of several case studies from around the globe (Israel, India, Turkey, Kyrgyzstan, Tibet, China and Europe), this brief provides a unique way to understand the implication of the methodological framework for climate studies. The book emphasizes the importance of field-based modern investigations to establish baseline characteristics of lake basins according to changes in environmental conditions. It also unveils the role of paleoclimate studies in climate model validation to forecast future climate variability. The book is a valuable resource for early career researchers interested in climate studies especially those using lake sediments as climate archive.
    Type of Medium: Online Resource
    Pages: X, 140 p. 23 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031347092
    Series Statement: SpringerBriefs in Environmental Science,
    DDC: 550
    Language: English
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  • 75
    Keywords: Earth sciences. ; Geochemistry. ; Paleontology . ; Earth Sciences. ; Geochemistry. ; Paleontology.
    Description / Table of Contents: Sedimentary organic matter: origin, productivity, preservation and role in source-rock development -- Practical guide for petroleum source rock interpretation -- Source rock thermal maturity based on oxidation and pyrolysis methods -- Source rocks forward modelling: significance and approach -- Optical kerogen analysis -- Effective source-rock evaluation strategies for the identification of profitable plays in the Permian Basin, USA -- High-resolution palynostratigraphy and palynofacies of the Upper Cretaceous and K/Pg boundary, Sirt Basin, Libya: A case study -- Viability of the upper member of the Mississippian Lodgepole Formation as an economic source rock in the Williston Basin -- Integration of palynological and foraminiferal analyses toward evaluation of the hydrocarbon potential in the Orange Basin, SW Africa -- Palynofacies, organic petrography and hydrocarbon potential of the Toarcian oil shale in the Tibetan Tethys, China -- Organic facies, paleoenvironment, and hydrocarbon source potential of the Cretaceous Mancos and Gallup formations, San Juan Basin, New Mexico -- Petroleum system analysis of the main Paleozoic source rocks in western Iraq: A 1D basin modelling approach -- Source rock quality and continuous petroleum system in the Ranikot Formation (Kirthar Foldbelt, Pakistan) based on principal organic geochemistry -- Egyptian Red Sea unconventional resource potential of the Upper Cretaceous-Paleogene black shales.
    Abstract: This book is directed to those who are interested in petroleum geology, especially source rock from both academia and industrial societies. Our chapter-based book is written by a list of world-class subject-matter experts. The book includes recent advancements in analytical source rock characterization methods with some case studies. It is also used as part of a course curriculum or guide for source rock interpretation for all researcher categories. Significant improvement in the source rock characterization techniques in the last two decades and the knowledge is disseminated in a huge amount of papers and studies. The book intends to collect these recent advancements in one textbook to benefit students and researchers in general. In addition, it is supplemented by many case studies from all over the world that represent important data sets for the regional geology of these areas.
    Type of Medium: Online Resource
    Pages: XIV, 293 p. 213 illus., 194 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031163968
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 550
    Language: English
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  • 76
    Keywords: Physical geography. ; Machine learning. ; Geology. ; Natural disasters. ; Earth System Sciences. ; Statistical Learning. ; Geology. ; Natural Hazards.
    Description / Table of Contents: Chapter1-Intelligent methods and motivations to use in volcanology and seismology -- Chapter2-Machine Learning: The concepts -- Chapter 3 - Machine Learning Applications in volcanology and seismology -- Chapter 4 - Deep Learning: The concepts -- Chapter 5:Deep Learning: Applications in Seismology and Volcanology -- Chapter 6: Evolutionary Algorithms with focus on Genetic Algorithm -- Chapter 7: Application of Genetic Algorithm in volcanology and seismology.
    Abstract: This book presents intelligent methods like neural, neuro-fuzzy, machine learning, deep learning and metaheuristic methods and their applications in both volcanology and seismology. The complex system of volcanoes and also earthquakes is a big challenge to identify their behavior using available models, which motivates scientists to apply non-model based methods. As there are lots of seismology and volcanology data sets, i.e., the local and global networks, one solution is using intelligent methods in which data-based algorithms are used. .
    Type of Medium: Online Resource
    Pages: XVII, 203 p. 219 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031154324
    Series Statement: Advances in Volcanology, An Official Book Series of the International Association of Volcanology and Chemistry of the Earth’s Interior,
    DDC: 550
    Language: English
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  • 77
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geophysics. ; Rheology. ; Mathematics Data processing. ; Petrology. ; Geophysics. ; Rheology. ; Computational Mathematics and Numerical Analysis. ; Petrology.
    Description / Table of Contents: Chapter 1. Background, Mathematic Preliminaries and Notations -- Chapter 2. Orientation of Fabric Elements -- Chapter 3. Stress, Strain, and Elasticity -- Chapter 4. Deformation: Strain and Rotation -- Chapter 5. Flow: Strain Rate and Vorticity -- Chapter 6. Flow and Finite Deformation in Tabular Zones -- Chapter 7. Constitutive Equations -- Chapter 8. Rotation of Rigid Objects in Homogeneous Flows -- Chapter 9. Further Analysis of Spheroids in Simple Shearing Flows -- Chapter 10. Eshelby’s Inclusion and Inhomogeneity Problem -- Chapter 11. Viscous Inclusions in Anisotropic Materials -- Chapter 12. Two-Dimensional Inclusion Problems -- Chapter 13. Effective Stiffnesses of Heterogeneous Materials -- Chapter 14. Application Example 1: An Elastic Prolate Object in a Viscous Matrix -- Chapter 15. Application Example 2: A Penny-Shaped Viscous Inclusion in an Elastic Matrix -- Chapter 16. Application Example 3: Deformation around a Heterogeneity: Flanking Structures -- Chapter 17. Generalization of Eshelby's Formalism and a Self-Consistent Model for Multiscale Rock Deformation.
    Abstract: The book integrates theory, numerical methods, and practical applications seamlessly. MATLAB and MathCad programs are provided for readers to master the theory, understand the approach, and to further develop and apply the methods to geological problems. Multiscale and multi-physics investigations of Earth and planetary processes have been an active trend of research in Earth Sciences, thanks to the development of scientific computation and computer software and hardware. Based on the author's research and teaching over the past 15 years, the book stands alone as the first comprehensive text in unifying fundamental continuum micromechanics theory, geometric/kinematic analysis, and applications. The book should appeal to a broad audience of students and researchers, particularly those in the fields of structural geology, tectonics, (natural and experimental) rock deformation, mineral physics and rheology, and numerical modeling of multiscale and coupling processes.
    Type of Medium: Online Resource
    Pages: XXI, 416 p. 104 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031233135
    Series Statement: Springer Geophysics,
    DDC: 550
    Language: English
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  • 78
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Physical geography. ; Atmospheric science. ; Oceanography. ; Earth System Sciences. ; Atmospheric Science. ; Ocean Sciences.
    Description / Table of Contents: The environment in the Solar System -- The fluid environment of the Earth -- Thermodynamics of the atmosphere and the ocean -- Chemical kinetics -- Fluid dynamics -- General circulation of the atmosphere -- General circulation of the ocean -- Biogeochemical Cycles -- Greenhouse E↵ect-Chemistry Climate Connection -- The Perturbed Atmosphere -- Some chemistry of the Sea -- Aerosols, Clouds and Rain -- Atmosphere-Sea Interactions -- The Fluid Environment in.
    Abstract: The book is conceived at two levels. An introductory one intended for undergraduate and/or environmental studies students and the other (in the appendix) for advanced students (graduate). The book is different from others on the same subject which are either too descriptive or too much specialized. Beside there are large sections on biogeochemistry not usually found in other textbooks. Whenever possible an approach based on entropy considerations is introduced. The book includes a quite classical introduction to the thermodynamics of ocean and atmosphere, then the circulation of the ocean and atmosphere, the connection climate-chemistry with main emphasis on the carbon dioxide problem. The chemistry is also considered in connection with the polluted atmosphere and ocean and particulate in the atmosphere . A chapter is dedicated to the biogeochemical cycles which are solved both with the integration of a system of equations or matrix algebra. An original chapter is dedicated to sea-atmosphere interactions which includes the monsoons meteorology, hurricanes and the ENSO phenomena. Finally a concise description of the fluid environments in the Solar System is given.
    Type of Medium: Online Resource
    Pages: XVI, 384 p. 156 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315398
    DDC: 550
    Language: English
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  • 79
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Keywords: Earth sciences. ; Physical geography. ; Environment. ; Science Study and teaching. ; Earth Sciences. ; Physical Geography. ; Environmental Sciences. ; Science Education.
    Description / Table of Contents: Searching for traces on our doorstep -- All around the glacier -- Distribution of ice and cold regions -- Glaciations during the geological past -- Glaciers shape landscapes -- The influence of glacial meltwater -- Shaping shapes away from glaciated areas -- Glaciers and sea level -- The next cold period is sure to come.
    Abstract: This book combines facts and interesting questions about the "Ice Age" with the topic of "Global Warming", Both these topics are the current topics which the media addresses on an almost daily basis. The author emphasizes that we are currently living in an ice age- a geological epoch in which there are glaciated areas on a larger scale. The traces of these cold periods can be seen and traced very well in the landscape in large parts of Europe, including northen and southern Germany. The book is aimed at university students of geosciences, but it is equally suitable reading for interested people and high school students. Upon reading this book, the targeted group will be enabled to see the traces of the ice age and better understand them in the surrounding landscapes by themselves. The author Wolfgang Fraedrich teaches geology and geography education at a Hamburg secondary school and accompanies students at the "Schülerforschungszentrum Hamburg" in geoscientific research projects. He is the author of numerous textbooks and non-fiction books and is since 40 years co-editor of the journal "geographie heute", with well over 300 publications. Through numerous excursions with adults and various research trips with school groups as part of the supervision of the program “Jugend forscht”, he has become acquainted with the most diverse corners of the earth. In addition to volcanism and the formation of mountain landscapes, glacial regions play a particularly important role. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: IX, 151 p. 79 illus., 78 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662658864
    DDC: 550
    Language: English
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  • 80
    Keywords: Earth sciences. ; Geology. ; Geophysics. ; Oceanography. ; Geography. ; Earth Sciences. ; Geology. ; Geophysics. ; Ocean Sciences. ; Earth and Environmental Sciences.
    Description / Table of Contents: Ocean Physics -- Ocean Biology -- Ocean Chemistry -- Marine Geology -- Marine Geophysics -- Marine Ecology and Environmental Management -- Physical and Biological interactions -- Oceanological Technology and Instrumentation.
    Abstract: The book presents the most relevant research of the participants of the VII International Conference of Young Scientists "Complex Investigation of the World Ocean" (CIWO-2023). This conference was held at Saint Petersburg State University in May 15-19, 2023 (Saint Petersburg, Russia). It covers a wide range of fundamental and applied marine and limnology studies combined in eight sections: Ocean Physics, Ocean Biology, Ocean Chemistry, Marine Geology, Marine Geophysics, Marine Ecology and Environmental Management, Physical and Biological interactions (interdisciplinary section), Oceanological Technology and Instrumentation. The aim of this book is to show the relevance of the marine research due to the crucial role of the World Ocean in determining climate change on Earth, huge resources (fish resources, oil, gas and ore deposits, etc.) and intensive development of infrastructure in coastal and offshore zones. All these topics were marked within the framework of realization of the United Nations Decade of Ocean Science for Sustainable Development (2021-2030). The studies presented in the book covers the wide spectrum of different the most important marine and limnology issues: thermohaline structure of water body and interactions between ocean and atmosphere, dynamic of the ocean, marine ice in polar regions, biodiversity of the marine ecosystems, adaptation of marine life to climate changes, geological and geophysical investigations in oil and gas regions, sedimentation, paleooceanology and biostratigraphy, hydrochemistry of estuary regions and carbon fluxes, microplastic pollution of the ocean, eutrophication and etc.
    Type of Medium: Online Resource
    Pages: XII, 493 p. 262 illus., 227 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031478512
    Series Statement: Springer Proceedings in Earth and Environmental Sciences,
    DDC: 550
    Language: English
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  • 81
    Keywords: Earth sciences. ; Sedimentology. ; Geology. ; Geochemistry. ; Mineralogy. ; Earth Sciences. ; Sedimentology. ; Geology. ; Geochemistry. ; Mineralogy.
    Description / Table of Contents: Section 1. Sedimentology, Stratigraphy, Paleontology -- Section 2. Geochemistry, Mineralogy, Petrology, Volcanology -- Section 3. Structural Geology, Tectonics, Geodynamics -- Section 4. Petroleum and Energy Engineering, Petroleum Geology.
    Abstract: This edited book is based on the accepted papers for presentation at the 1st MedGU Annual Meeting, Istanbul 2021. With four parts spanning a large spectrum of geological, geochemical, geophysical and petroleum topics, this book presents a series of newest research studies that are nowadays relevant to Middle East, Mediterranean region, and Africa. The book covers various topics from the fields of (1) sedimentology, stratigraphy, paleontology, (2) geochemistry, mineralogy, petrology, volcanology, (3) structural geology, tectonics, geodynamics, and (4) petroleum and energy engineering, and petroleum geology. The content of these papers provides new scientific knowledge for further understanding new case studies and approaches in these various topics.
    Type of Medium: Online Resource
    Pages: XXIX, 261 p. 161 illus., 148 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031432224
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 550
    Language: English
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  • 82
    Keywords: Neurosciences. ; Biomedical engineering. ; Nanotechnology. ; Biophysics. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Nanoengineering. ; Bioanalysis and Bioimaging. ; Biological Imaging.
    Description / Table of Contents: Part 1 -- Optically-Pumped Magnetometers Compatible with Large Transient Magnetic Fields -- Small animal biomagnetism applications -- Supine OPM-MEG in Multi-layer Cylindrical Shield -- Ambulatory MEG Arrays -- Part 2 -- "Tri-axial helium-4 optically-pumped -- magnetometers for MEG" -- Person-Sized Magnetoencephalography Systems with Optically Pumped Magnetometers -- On-scalp MEG with High-Tc SQUIDs -- "Fiber Coupled OPM in Purely Coil -- Shielded Environment" -- SERF-OPM usability for MEG in two-layer shielded rooms -- Turning OPM-MEG into a Wearable Technology -- Part 3 -- OPM Gradiometer for Magnetorelaxometry -- Unshielded High Bandwidth Magnetorelaxometry of Magnetic Nanoparticles with Optically Pumped Magnetometers -- Adult Magnetocardiography: Principles and Clinical Practice -- Fetal Magnetocardiography with OPMs -- Emerging MR sensors for biomagnetic measurements -- Index.
    Abstract: This contributed volume reviews the latest advances in all the new technologies currently developed for MagnetoEncephaloGraphy (MEG) recordings, as well as sensor technologies and integrated sensor arrays for on-scalp MEG. The book gives an account of the first MEG imaging studies and explores the new field of feasible, experimental paradigms of on-scalp MEG. This is an ideal book for engineers, researchers, and students in the neurosciences interested in MEG imaging. .
    Type of Medium: Online Resource
    Pages: IX, 315 p. 104 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031053634
    DDC: 612.8
    Language: English
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  • 83
    Keywords: Neurosciences. ; Animal culture. ; Veterinary medicine. ; Neuroscience. ; Animal Science. ; Veterinary Science.
    Description / Table of Contents: Rodents -- Carnivores -- Sheep and goats -- Swine -- Rabbits -- Bovines -- Non-human primates -- Humans -- Squirrels.
    Abstract: Modern neuroscience has presented new opportunities for exploring the molecular and neural mechanisms controlling specific social responses. This book reviews insights into the neural circuits underlying a particularly fascinating form of social interaction, parental behavior. This book presents a detailed review of maternal and paternal behavior of particular mammalian species. It offer neuroscientists a spectrum of specific mammals that can be used as experimental models to explore particular topics on the functions of the nervous system. It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild. It also discusses the implications of this research for human parental behavior. .
    Type of Medium: Online Resource
    Pages: V, 309 p. 45 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030977627
    Series Statement: Advances in Neurobiology, 27
    DDC: 612.8
    Language: English
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  • 84
    Keywords: Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Abstract: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Type of Medium: Online Resource
    Pages: XIV, 256 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811943249
    DDC: 612.8
    Language: English
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  • 85
    Keywords: Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Abstract: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Type of Medium: Online Resource
    Pages: XV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676062
    DDC: 612.8
    Language: English
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  • 86
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Stem cells. ; Nervous system Regeneration. ; Neuroscience. ; Stem Cell Biology. ; Regeneration and Repair in the Nervous System.
    Description / Table of Contents: 1 Regenerative Therapies in Ischemic Stroke Recovery -- 2 Application of Nanotechnology In Stroke Recovery -- 3 Nanotechnology: A daydream for advanced Imaging, Diagnosis and Therapeutic Approach for Cerebral Ischemia -- 4 Cell-Mediated Neurorestorative Mechanisms Underpinning Beneficial Effects in Ischemic Stroke -- 5 Induced Pluripotent Stem Cells for the Treatment of Neurodegenerative Disease: Current and Future Prospects -- 6 Imaging of Stem Cell Therapy for Stroke and Beyond -- 7 Nano-Medicine Mediated Stem Cell Therapeutics In Stroke -- 8 The Influence of Preconditioning on the Homing Behaviour of Stem Cells -- 9 Role of microRNAs in stroke pathology and recovery -- 10 Exosomes as a diagnostic tool and stem cells exosomes as a promising cell-based cell-free therapeutic tool for ischemic stroke 11 Role of nanomedicine in treating ischemic stroke -- 12 Insights into therapeutic targets in stroke -- 13 Signalling Pathways of Interest for Recovery from Ischemic Stroke.
    Abstract: This book illustrates the importance and significance of regenerative medicine in stroke recovery. It discusses stem-cell-based treatment strategies and offers mechanistic insights into their role in neurological recovery. It also examines the challenges and advances in using adult stem cells for enhanced therapeutic efficacy. Further, it presents the strategies as well as the strengths and weaknesses of various delivery methods to administer stem cells in ischemic stroke. It examines the role of non-coding RNA in our understanding the stroke pathogenesis, their regulatory role in ischemic stroke and potential as biomarkers and therapeutic targets. Lastly, it explores exosomes in the treatment of stroke, and the underlying mechanism of their action as therapeutic vectors for stroke. Given its scope, it is an excellent resource for neurologists, neuroscientists and researchers involved in regenerative therapy for stroke.
    Type of Medium: Online Resource
    Pages: XIII, 353 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811685620
    DDC: 612.8
    Language: English
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  • 87
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Cognitive neuroscience. ; Social evolution. ; Neuroscience. ; Cognitive Neuroscience. ; Social Evolution.
    Description / Table of Contents: Part I Differentiation-Integration Dynamics: Ultimate Causes -- Chapter 1: Introduction -- Chapter 2: Purposeless Design -- Chapter 3: Darwinian Evolutionary Theory -- Chapter 4: Principles of Differentiation and Integration -- Chapter 5: The Information Trend in Science -- Chapter 6: Is Social Cohesion a Different Mechanism of Evolution? -- Part II Roots and Mechanisms: Proximate Causes -- Chapter 7: Fundamental Physical Forces, Genes, and Epigenetics -- Chapter 8: Biological Origins -- Chapter 9: Neural Mechanisms of Sociality -- Chapter 10: Psychological Features -- Chapter 11: Cognitive Science Underpinnings -- Chapter 12: A Sociological Systems Theory -- Chapter 13: Developmental Roots -- Chapter 14: Metaphysical, Religious, and Spiritual Aspects -- Part III Survival Value -- Chapter 15: Sociality’s Survival Value -- Part IV Conclusions -- Chapter 16: A New Framework: A Theory of Integration.
    Abstract: This book is an exploration of the integration-differentiation dynamics that result in a drive, or impulse, toward human sociality, arguing that our need to connect with other people is as fundamental as our need for food and shelter. In The Social Impulse: The Evolution and Neuroscience of What Brings Us Together, Jaime Pineda presents the evidence that social cohesion is a complementary force to natural selection, the Darwinian drive for differentiation and diversity. The book addresses the distinctive aspects of social behavior that arise from integration principles and seeks to answer the following questions: (1) Why does social cohesion arise? (2) What is the history of social dynamics? (3) How does social cohesion work? (4) When do the developmental aspects of social dynamics arise? A final section of the book addresses the value of sociality and social cohesion. By exploring the differences, similarities, and, most important, the interactivity between natural selection and social cohesion, this unique book provides a wealth of interesting, challenging, and unexpected insights.
    Type of Medium: Online Resource
    Pages: XXV, 190 p. 7 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084393
    DDC: 612.8
    Language: English
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  • 88
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Pain medicine. ; Clinical psychology. ; Neuroscience. ; Pain Medicine. ; Clinical Psychology.
    Description / Table of Contents: Chapter 1. Conceptualising Pain in Critically-Ill Neonates or Infants -- Chapter 2. Pain in the Fetus and the Preterm Baby -- Chapter 3. Developmental Influences on the Meanings of Pain in Children -- Chapter 4. “Ooh, You Got to Holler Sometime:” Pain Meaning and Experiences of Black Older Adults -- Chapter 5. Exploring the Meaning of Chronic Low Back Pain as a Life of ‘Living Death’ in Rural Nigeria -- Chapter 6. Painworld: A Phenomenological View of Veteran Experiences of Living with Chronic Pain -- Chapter 7. “It’s Just One of Them Things You’ve Got to Try and Manage”: Meanings of Pain for People with Brain Injury.
    Abstract: This book, the third and final volume in the Meaning of Pain series, describes what pain means to people with pain in “vulnerable” groups, and how meaning changes pain – and them – over time. Immediate pain warns of harm or injury to the person with pain. If pain persists over time, more complex meanings can become interwoven with this primitive meaning of threat. These cognitive meanings include thoughts and anxiety about the adverse consequences of pain. Such meanings can nourish existential sufferings, which are more about the person than the pain, such as loss, loneliness, or despair. Although chronic pain can affect anyone, there are some groups of people for whom particular clinical support and understanding is urgently needed. This applies to “vulnerable” or “special” groups of people, and to the question of what pain means to them. These groups include children, women, older adults, veterans, addicts, people with mental health problems, homeless people, or people in rural or indigenous communities. Several chapters in the book focus on the lived experience of pain in vulnerable adults, including black older adults in the US, rural Nigerians, US veterans, and adults with acquired brain injury. The question of what pain experience could mean in the defenceless fetus, neonate, pre-term baby, and child, is examined in depth across three contributions. This book series aspires to create a vocabulary on the “meanings of pain” and a clinical framework with which to use it. It is hoped that the series stimulates self-reflection about the role of meaning in optimal pain management. Meanings of Pain is intended for people with pain, family members or caregivers of people with pain, clinicians, researchers, advocates, and policy makers. Volume I was published in 2016; Volume II in 2019.
    Type of Medium: Online Resource
    Pages: VII, 147 p. 5 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030958251
    DDC: 612.8
    Language: English
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  • 89
    Keywords: Neurosciences. ; Materials Analysis. ; Imaging systems. ; Nervous system Diseases. ; Nervous system Radiography. ; Neuroscience. ; Imaging Techniques. ; Neurological Disorders. ; Neuroradiology.
    Description / Table of Contents: Optical coherence tomography in brain gliomas detection and peritumoral white matter state evaluation -- Two Photon Fluorescence Lifetime Imaging of Reduced nicotinamide adenine dinucleotide in Brain Research -- Types of Raman Scattering Techniques for Neurodegenerative Diseases -- Drosophila brain advanced multiphoton imaging -- Myelin imaging -- Brainbow: Principle, Technique and Applications -- Photoacoustic Imaging of Brain -- Photodynamic therapy of brain diseases -- Advanced Magnetic Resonance Imaging (MRI) of Brain -- Indirect imaging -- Multimodal Noninvasive Imaging Strategies for Clinically Monitoring Degenerative Disorders of the Brain -- Machine learning approach in brain imaging -- Transgenic Brain mapping Techniques in Drosophila melanogaster -- Behavioural phenotyping to study cognitive and non-cognitive symptoms in the rodent model of Alzheimer's disease.
    Abstract: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.
    Type of Medium: Online Resource
    Pages: XII, 257 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913525
    DDC: 612.8
    Language: English
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  • 90
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. The Auditory Cognitive Neuroscience of Speech Perception in Context -- 2. Subcortical Processing of Speech Sounds -- 3. Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology -- 4. A Parsimonious Look at Neural Oscillations in Speech Perception -- 5. Extracting Language Content From Speech Sounds: The Information Theoretic Approach -- 6. Speech Perception under Adverse Listening Conditions -- 7. Adaptive Plasticity in Perceiving Speech Sounds -- 8. Development of Speech Perception -- 9. Interactions Between Audition and Cognition in Hearing Loss and Aging.
    Abstract: This volume reviews contemporary developments in the auditory cognitive neuroscience of speech perception, including both behavioral and neural contributions. It serves as an important update on the current state of research in speech perception. The Auditory Cognitive Neuroscience of Speech Perception in Context Lori L. Holt, and Jonathan E. Peelle Subcortical Processing of Speech Sounds Bharath Chandrasekaran, Rachel Tessmer, and G. Nike Gnanateja Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology Yulia Oganian, Neal P. Fox, and Edward F. Chang A Parsimonious Look at Neural Oscillations in Speech Perception Sarah Tune, and Jonas Obleser Extracting Language Content From Speech Sounds: The Information Theoretic Approach Laura Gwilliams, and Matthew H. Davis Speech Perception under Adverse Listening Conditions Stephen C. Van Hedger, and Ingrid S. Johnsrude Adaptive Plasticity in Perceiving Speech Sounds Shruti Ullas, Milene Bonte, Elia Formisano, and Jean Vroomen Development of Speech Perception Judit Gervain Interactions Between Audition and Cognition in Hearing Loss and Aging Chad S. Rogers, and Jonathan E. Peelle .
    Type of Medium: Online Resource
    Pages: XVI, 252 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030815424
    Series Statement: Springer Handbook of Auditory Research, 74
    DDC: 612.8
    Language: English
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  • 91
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Behavioral Neuroscience.
    Description / Table of Contents: Part I Preclinical Research: Neuroendocrine Mechanisms of Social Bonds and Separation Stress in Rodents, Dogs, and Other Species -- Methods and Challenges in Investigating Sex-Specific Consequences of Social Stressors in Adolescence in Rats: Is It the Stress or the Social or the Stage of Development?- Social stress-induced neuroinflammation and mitochondrial dysfunction as a link to depression and cardiovascular disease comorbidity -- Mean Girls: Social Stress Models for Female Rodents -- Development of Mixed Anxiety/ Depression-Like State as a Consequence of Chronic Anxiety: Review of Experimental Data -- Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse -- Social Stress and Aggression in Murine Models -- More or less: glucocorticoid roles in aggression -- Neurobiological Bases of Urges for Alcohol Consumption After Social Stress -- Epigenetics of Aggression -- Part II Human Research: Early Life Stress and Neurodevelopment in Adolescence: Implications for Risk and Adaptation -- Effects of Parenting Environment on Child and Adolescent Social-Emotional Brain Function -- The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans -- Social Acts and Anticipation of Social Feedback -- Clinical Outcomes of Severe Forms of Early Social Stress -- Childhood Violence Exposure, Inflammation, and Cardiometabolic Health -- Social Support Effects on Neural Stress and Alcohol Reward Responses -- Neural Underpinnings of Social Stress in Human Addiction.
    Abstract: Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
    Type of Medium: Online Resource
    Pages: VIII, 515 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031042560
    Series Statement: Current Topics in Behavioral Neurosciences, 54
    DDC: 612.8
    Language: English
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  • 92
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Psychiatry. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Section I. Anhedonia – History, Etiology, and Assessments -- 1. Historical Perspective -- 2. Clinical and Behavioral Assessments -- 3. Developmental Trajectories: Preclinical -- 4. Developmental Trajectories: Clinical -- 5. Genetics Contributions -- 6. Environmental Contributions -- Section II. Anhedonia in Psychiatric and Neurological Disorders -- 7. Depression and Bipolar Disorder -- 8. Schizophrenia -- 9. Substance Use Disorder -- 10. Nicotine Dependence -- 11. Posttraumatic Stress Disorder -- 12. Anxiety -- 13. Eating Disorders -- 14. Autism and Developmental Disorders -- 15. Neurodegenerative Disorders -- Section III. Reward Processing Systems in Anhedonia -- Reward Responsiveness -- 16. Pleasure -- 17. Anticipation -- Reward Valuation -- 18. Reward Value – Delay and Reward Magnitude -- 19. Effort/Motivation -- Reward Learning -- 20. Reward Prediction Error -- 21. Probabilistic and Reinforcement Learning -- Section IV. Treatments -- 22. Pharmacological Treatments for Anhedonia -- 23. Psychological Treatments for Anhedonia -- 24. Neurostimulation -- Section V. Special Topics -- 25. Inflammation and Anhedonia -- 26. Computational Modeling of Anhedonia -- 27. Anhedonia and Suicide.
    Abstract: Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.
    Type of Medium: Online Resource
    Pages: XI, 535 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031096839
    Series Statement: Current Topics in Behavioral Neurosciences, 58
    DDC: 612.8
    Language: English
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  • 93
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nutrition   . ; Quantitative research. ; Nervous system Diseases. ; Neuroimmunology. ; Neuroscience. ; Nutrition. ; Data Analysis and Big Data. ; Neurological Disorders. ; Neuroimmunology.
    Description / Table of Contents: Chapter 1. Nutrigenomics; a broader concept -- Chapter 2. Gene-environment interaction -- Chapter 3. Gene-gut-brain - axis (gene–based personalized medicine) -- Chapter 4. Nutrigenomics of aging -- Chapter 5. Nutrigenomics and Mental health -- Chapter 6. Nutrigenomics and neurodevelopmental disorders -- Chapter 7. Nutrigenomics and Alzheimer’s disease -- Chapter 8. Nutrigenomics and Parkinson’s Disease -- Chapter 9. Nutrigenomics, nutrigenetics and big data -- Chapter 10. Nutrigenomics and Development -- Chapter 11. Early Child malnutrition and neurodevelopment -- Chapter 12. The emerging role of vit D deficiency and Parkinson’s Disease risk -- Chapter 13. Nutrigenomics and autophagy crosstalk -- Chapter 14. Nanoparticles in food additives and brain health.
    Abstract: This book highlights the effect of complex interactions between numerous genetic and environmental factors, including food intake, physical activity, age, and stress on brain physiology and function. It further discusses the mechanistic connection between nutrition and aging towards understanding the effect of the brain on longevity. The book also reviews the efficiency of nutraceutical compounds for treating and preventing of neurodevelopmental and neurodegenerative disorders. It also discusses the role of gut microbiota on the gut-brain axis and presents the role of nutrition in neurological inflammatory diseases.
    Type of Medium: Online Resource
    Pages: VII, 234 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692055
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 94
    Keywords: Neurosciences. ; Psychobiology. ; Human behavior. ; Pharmacology. ; Psychiatry. ; Pain medicine. ; Neuroscience. ; Behavioral Neuroscience. ; Pharmacology. ; Psychiatry. ; Pain Medicine.
    Description / Table of Contents: CLINICAL PROFILE AND TREATMENTS -- ADHD in children and adults: diagnosis and prognosis -- Treatment strategies -- Psychostimulants – treatment efficacy and problems -- Recent developments and future options for pharmacological treatments for ADHD -- GENETICS -- Genetics of ADHD (including CNVs) -- Genes , cognitive function and ADHD -- Epigenetics and ADHD -- CO-MORBIDITY -- ADHD and comorbid depression -- ADHD and autism -- Aggression and ADHD -- Obesity and ADHD (+ cytokines?) -- Sleep circadian rhythms and ADHD -- Substance misuse -- ASSESSING BRAIN FUNCTION / DYSFUNCTION -- EEG and ADHD (the skeptical view) -- Update on imaging – with connectivity -- Visual processing substrates for ADHD -- Cortical microstructure / connectivity -- ANIMAL AND IN VITRO STUDIES -- Critique of animal models -- Update on circuits for impulsive behaviour -- Zebrafish -- Update on DA transporter and ADHD -- Arousal, noradrenaline and ADHD -- FUTURE DIRECTIONS -- Stem cells for disease modelling -- Microbiome and ADHD -- Adult ADHD.
    Abstract: New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest developments in preclinical and clinical research of Attention Deficit Hyperactivity Disorder. As well as updating key chapters that were included in an earlier edition, this volume includes some new topics that are attracting a great deal of interest and point the way to new and promising directions for future research. The chapters follow five main themes: Current perspectives on the clinical profile of ADHD and its treatment, common co-occurring conditions, neurobiological studies examining brain function and genetics, animal and in vitro studies, and future directions. This combination of topics emphasises the translational relevance and validity of preclinical research so as to enable a better understanding of ADHD and to highlight the promising strategies for developing new treatments.
    Type of Medium: Online Resource
    Pages: VIII, 501 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031118029
    Series Statement: Current Topics in Behavioral Neurosciences, 57
    DDC: 612.8
    Language: English
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  • 95
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nervous system Diseases. ; Cognitive neuroscience. ; Developmental neurobiology. ; Nutrition   . ; Neuroscience. ; Neurological Disorders. ; Cognitive Neuroscience. ; Development of the Nervous System. ; Nutrition.
    Description / Table of Contents: Chapter 1. Micronutrients and Neurogenesis -- Chapter 2. Vit-E and Cognitive functions: What is the Interplay? -- Chapter 3. Microbiome and micronutrients -- Chapter 4. Iodine and Brain -- Chapter 5. Tocotrienol and Brain -- Chapter 6. Micronutrients and Depression -- Chapter 7. Micronutrients and Epilepsy -- Chapter 8. Iron Deficiency and brain cognitive functions -- Chapter 9. Micronutrients and PD -- Chapter 10. Malnutrition of Micronutrients and the brain disorders -- Chapter 11. Connections between micronutrients, cerebral monoamines and related brain disorders -- Chapter 12. Micronutrients and Autism -- Chapter 13. Edible Bird’s Nest as Brain Food -- Chapter 14. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Traumatic Brain Injury? -- Chapter 15. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Alzheimer’s Disease? -- Chapter 16. Nutrigenomics and Brain.
    Abstract: This book comprehensively reviews the relationship between micronutrients and brain in health and diseases. It explains the relationship between micronutrients and brain functions, neurogenesis, and cognitive functions. The book also explores the relationship between micronutrients and brain disorders including depression, epilepsy, PD, and Autism. It further explores the recent advancements in understanding the important role of micronutrients as therapeutics in various brain disorders like TBI and AD. Lastly, it presents an overview of micronutrients as neuroprotective agents along with the main principles of nutrigenomics.
    Type of Medium: Online Resource
    Pages: XVII, 308 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811664670
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 96
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Cognitive psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of mind. ; Neurology . ; Neuroscience. ; Cognitive Psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of Mind. ; Neurology.
    Description / Table of Contents: Learning the Languages -- Humanity’s Search for Mind and the Subject: A Brief Review of the Evolution of Neuropsychobiology -- An “Ideographic,” Suprapersonal Language of Rules and Universal Symbols: Alwyn Scott and Nonlinear Dynamics -- A “Demotic,” First-Person Language of the Individual and the Social System: Apuleius and the Myth of Psyche -- The Language of the Objective Observer: Gerald Edelman and Neurodarwinism: Antonio Damasio and the Feeling of Knowing -- Seeking the Understanding -- Consciousness -- The Unconscious -- The Database -- Affectivity -- The Neural/Mental Gap: Intuition, Self and Ego, a Trilingual Map -- Applying the Knowledge -- The Three Languages and Science: A New Scientific Paradigm? -- The Three Languages and Treatment -- The Psychotherapeutic Dialogue: Intersubjectivity -- The Role of a New Science for Psyche Upon Society and Culture.
    Abstract: The study of the brain-mind complex has been hampered by the dichotomy between objective biological neuroscience and subjective psychological science. The two antithetical avenues of research are partly responsible for the failure to unravel the transformation of neural events into mental images: how matter becomes imagination, and vice versa; is the brain’s consciousness equivalent to Ego consciousness? Is the ego the self? In its new and updated edition, “The Rosetta Stone of the Human Mind: Three Languages to Integrate Neurobiology and Psychology” illustrates how the simultaneous use of the languages of neurobiology, of mathematics, and of the humanities, enriches the understanding of the neural and mental realms and adds new dimensions to our perception of neuropsychological events. Dr. Sanguineti shows how the two seemingly dichotomous approaches are similar in what they describe, and he explores how the awareness and application of these perspectives are helpful in getting a deeper theoretical grasp on major mental events, giving us a better understanding of individual minds, and fostering a more integrated therapeutic intervention. The intended readers include neuroscientists, psychiatrists, psychologists, and anyone interested in the human mind. Describes a model integrating biological neuroscience principles, subjective psychological science, and nonlinear physics and mathematics Offers a wide-ranging, holistic exploration of the mind and its conscious and unconscious realms, using myth, art, philosophy, neurobiology and basic sciences Introduces the future new paradigm for emergent science, the Poem, to replace the outdated classical reductionistic paradigm of the Machine.
    Type of Medium: Online Resource
    Pages: XXII, 167 p. 25 illus., 6 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030864156
    DDC: 612.8
    Language: English
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  • 97
    Keywords: Neurosciences. ; Proteins. ; Nervous system Diseases. ; Genetics. ; Neuroscience. ; Proteins. ; Neurological Disorders. ; Genetics.
    Description / Table of Contents: Chapter 1. Proteins Commonly Linked to Autism Spectrum Disorder -- Chapter 2. Protein Aggregation and Recycling -- Chapter 3. Neuron Membrane and Trafficking Protein Kinases (PKA&B) involved in ASD -- Chapter 4. Proteomic profiling in children with ASD -- Chapter 5. Molecular Protein biomarkers for developing diagnostics and therapeutic interventions.Gene Regulation in Autism. OR Neurodevelopmental Epigenomics -- Chapter 6. Chromatin and Epigenetic Regulation in ASD -- Chapter 7. Autism and the Scaffolding Protein Neurobeachin -- Chapter 8. Genomic Profiling in ADHD subjects -- Chapter 9. ADHD and Epigenetics Regulation -- Chapter 10. Proteomic Approach in ADHD -- Chapter 11. DHD and the Dopamine Transporter (DAT) -- Chapter 12. Protein Kinases involved in ADHD -- Chapter 13. ADHD and Cell Adhesion Molecule 1 – CAM 1 (CADM1 gene) -- Chapter 14. ASD and Cell Adhesion Molecule Astrotactin -- Chapter 15. Possible therapeutic interventions through proteins in ADHD.
    Abstract: This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.
    Type of Medium: Online Resource
    Pages: XV, 339 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811597817
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 98
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    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurology . ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry. ; Neuroscience. ; Neurology. ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry.
    Description / Table of Contents: Treatments Against Glutamatergic Excitotoxicity in Ischemic Stroke -- Definitions and Concepts of Stress -- Role of Glutamatergic Neurotransmission in the Pathophysiology of Stress-Related Disorders and Chronic Stress Response -- Current Glutamatergic Treatments and Future Directions for Glutamate-Based Management of Chronic Stress and Stress-Related Disorders -- The Role of the Glutamate System in Posttraumatic Stress Disorder and Glutamate-Based Treatments -- Glutamate in Migraine Neurobiology and Treatment -- Astrocyte Glutamate Transporter EAAT2 in Alzheimer Dementia -- The Glutamatergic System as a Target for the Development of New Pharmacological Treatments of Bipolar Disorder -- CNS Glutamate in Impulsive Aggression -- Glutamatergic Treatments for Parkinsons' Disease -- The Modulation of Glutamatergic Signaling as a Potential Therapeutic Strategy for Major Depression -- Glutamate-Based Treatment for Amyotrophic Lateral Sclerosis/Motor Neuron Disease -- Modulation of Glutamate for Chronic Pain Management -- Pharmacological Role of Glutamate Transporters in Substance Use Disorders -- Glutamate in Multiple Sclerosis: From Pathophysiology to Treatments -- The Role of Glutamate Dysregulation in the Etiology of ADHD -- Glutamate, Glutamatergic Drugs and Schizophrenia -- Glutamate and Epilepsy: An Insight from Temporal Lobe Epilepsy -- Glutamate Function in Anxiety Disorders and OCD: Evidence from Clinical and Translational Studies -- Modulators of Glutamatergic Signaling as Potential Treatments for Autism Spectrum Disorders.
    Abstract: This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.
    Type of Medium: Online Resource
    Pages: XXXV, 600 p. 43 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874803
    DDC: 612.8
    Language: English
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  • 99
    Keywords: Neurosciences. ; Neural circuitry. ; Bioinformatics. ; Computer science. ; Neuroscience. ; Neural Circuits. ; Computational and Systems Biology. ; Computer Science.
    Description / Table of Contents: PART I. Cellular Scale -- Chapter 1. Modelling Neurons in 3D at the Nanoscale -- Chapter 2. Modelling Dendrites and Spatially-Distributed Neuronal Membrane Properties -- Chapter 3. A User's Guide to Generalized Integrate-and-Fire Models -- Chapter 4. Neuron-glia Interactions and Brain Circuits -- Chapter 5. Short-term Synaptic Plasticity: Microscopic Modelling and (some) Computational Implications -- PART II. Molecular Scale -- Chapter 6. The Mean Field Approach for Populations of Spiking Neurons -- Chapter 7. Multidimensional Dynamical Systems with Noise -- Chapter 8. Computing Extracellular Electric Potentials from Neuronal Simulations -- Chapter 9. Bringing Anatomical Information into Neuronal Network Models -- PART III. Network Scale -- Chapter 10. Computational Concepts for Reconstructing and Simulating Brain Tissue -- Chapter 11. Reconstruction of the Hippocampus -- Chapter 12. Challenges for Place and Grid Cell Models -- Chapter 13. Whole-Brain Modelling: Past, Present, and Future.
    Abstract: This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. .
    Type of Medium: Online Resource
    Pages: XII, 359 p. 115 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030894399
    Series Statement: Cellular Neuroscience, Neural Circuits and Systems Neuroscience, 1359
    DDC: 612.8
    Language: English
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  • 100
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: Establishing the molecular and functional diversity of spinal motoneurons -- Chloride homeostasis in developing motoneurons -- Normal development and pathology of motoneurons: anatomy, electrophysiological properties, firing patterns and circuit connectivity -- Homeostatic regulation of motoneuron properties in development -- Homeostatic plasticity of the mammalian neuromuscular junction -- Diversity of mammalian motoneurons and motor units -- Synaptic projections of motoneurons within the spinal cord -- Recruitment of motoneurons -- Electrical properties of adult mammalian motoneurons.-The cellular basis for the generation of firing patterns in human motor units -- Motoneuronal regulation of central pattern generator and network function -- Extraocular motoneurons and neurotrophism -- Motoneuron diseases -- Electrical and morphological properties of developing motoneurons in postnatal mice and early abnormalities in sod1 transgenic mice -- From physiological properties to selective vulnerability of motor units in amyotrophic lateral sclerosis. .
    Abstract: This book aims to provide a comprehensive and timely review of new findings in motoneuron research. Recent findings have revealed that motoneurons are more complex and have more extensive functions than previously imagined. Some of the molecular and genetic pathways that orchestrate the development of motoneurons have been discovered, as have the mechanisms responsible for the selective innervation of muscles by specific pools of motoneurons. These novel findings are revolutionizing ideas about the function of motoneurons and have important implications for motoneuron disease. Chapters from several of the foremost figures in the field are included in this book and will emphasize how basic science is the engine driving the discovery of novel treatments for degenerative motoneuron diseases. Cutting edge developments in the use of pluripotent stem cells to correct motoneuron disease will be also be covered. This book would be useful to students of basic motoneuron physiology, locomotor behavior and motor control. This book would also be of interest to professional neuroscientists, neurologists, and neurosurgeons.
    Type of Medium: Online Resource
    Pages: XII, 400 p. 81 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031071676
    Series Statement: Advances in Neurobiology, 28
    DDC: 612.8
    Language: English
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