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1

Digitale Medien

Mutation of the ST7 tumor suppressor gene on 7q31.1 is rare in breast, ovarian and colorectal cancers (2001)

Thomas, Nicola A. ; Choong, David Y.H. ; Jokubaitis, Venta J. ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 379-380

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] The gene ST7 has recently been implicated as the broad-range tumor suppressor on human chromosome 7q31.1. We did not detect somatic mutations in ST7 in any of 149 primary ovarian, breast or colon carcinomas. These data suggest that epigenetic downregulation or haploinsufficiency, rather than ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng784

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2

Digitale Medien

Sex, flies and microarrays (2001)

Churchill, Gary A. ; Oliver, Brian

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 355-356

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Gene expression microarrays generate stunningly large data sets that require many hours of staring at overwhelmingly long spreadsheets and the frequent purchase of more RAM for laboratory computers. When designing a gene expression experiment, however, perhaps one should imagine that only a single ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1201-355

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3

Digitale Medien

Touching base (2001)

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 361-361

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Silencing crown gall Crown gall disease is responsible for substantial loss of perennial crops worldwide. It is caused by the soil bacterium Agrobacterium tumefaciens, which is introduced through wounds in the plant stem. Oncogenes introduced into the plant genome by the bacterium result in ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1201-361

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4

Digitale Medien

The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA (2001)

Mandel, H. ; Szargel, R. ; Labay, V. ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 491-491

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Nature Genet. 29, 337–341 (2001). The legend of Fig. 4 contains two incorrect lane references in the second sentence. A corrected legend follows. Fig. 4 Western-blot analysis of liver homogenate. We separated an equivalent of 2 mU citrate synthase from affected individual 21 of family 1-F ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1201-491a

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5

Digitale Medien

A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease–like 2 (2001)

Holmes, Susan E. ; O'Hearn, Elizabeth ; Rosenblatt, Adam ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 377-378

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] We recently described a disorder termed Huntington disease–like 2 (HDL2) that completely segregates with an unidentified CAG/CTG expansion in a large pedigree (W). We now report the cloning of this expansion and its localization to a variably spliced exon of JPH3 (encoding junctophilin-3), a ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng760

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6

Digitale Medien

The fragility of fertility (2001)

Yen, Pauline

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 243-244

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] With fewer than 50 genes or gene families—many expressed only in the testis—the Y chromosome is not essential for life. Its main task is to ensure that men can make and deliver sperm for the continuation of the species. The sex-determining role of the Y chromosome has been known for a ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1101-243

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7

Digitale Medien

Touching base (2001)

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 249-249

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Genes on the Fork Food derived from genetically modified organisms (GMOs) has a bad reputation in some circles, especially in Europe. In an effort to change public perception, Swiss immunologist Beda Stadler has put together a book of traditional recipes, from soups to desserts, which use GMOs as ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1101-249

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8

Digitale Medien

Mutations in a newly identified GTPase gene cause autosomal dominant hereditary spastic paraplegia (2001)

Zhao, Xinping ; Alvarado, David ; Rainier, Shirley ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 326-331

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] The hereditary spastic paraplegias (HSPs; Strümpell-Lorrain syndrome, MIM number 18260) are a diverse class of disorders characterized by insidiously progressive lower-extremity spastic weakness (reviewed in refs. 1–3). Eight autosomal dominant HSP (ADHSP) loci have been identified, the ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng758

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9

Digitale Medien

The promoter connection (2001)

Werner, Thomas

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 105-106

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Since the sequence of the yeast genome was determined in its entirety several years ago, it has served as a catalog of the genes contained in a single genome. On the other hand, large-scale gene expression studies using DNA microarrays now provide clues to the dynamic processes of life, especially ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1001-105

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10

Digitale Medien

The adaptable lin-39 (2001)

Chamberlin, Helen M.

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 106-107

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] A molecular geneticist will often submit a gene sequence to a database for comparison and will be pleased to identify regions of sequence similarity. The assumption is that sequence similarity allows one to extrapolate a possible molecular function for the gene based on previous work on other ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1001-106

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