ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles  (739)
  • Humans  (635)
  • Mice  (165)
  • 2005-2009  (739)
  • 2008  (739)
  • Physics  (739)
Collection
  • Articles  (739)
Source
Keywords
Publisher
Years
  • 2005-2009  (739)
Year
Journal
Topic
  • 1
    facet.materialart.
    Unknown
    The state of global hunger (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sastre, Juan -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1788-9. doi: 10.1126/science.322.5909.1788b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095923" target="_blank"〉PubMed〈/a〉
    Keywords: *Agriculture ; Developed Countries ; *Food Supply ; *Global Health ; Humans ; *Hunger ; *International Cooperation ; Malnutrition/*epidemiology/prevention & control
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Nuclear reprogramming in cells (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: Nuclear reprogramming describes a switch in gene expression of one kind of cell to that of another unrelated cell type. Early studies in frog cloning provided some of the first experimental evidence for reprogramming. Subsequent procedures included mammalian somatic cell nuclear transfer, cell fusion, induction of pluripotency by ectopic gene expression, and direct reprogramming. Through these methods it becomes possible to derive one kind of specialized cell (such as a brain cell) from another, more accessible, tissue (such as skin) in the same individual. This has potential applications for cell replacement without the immunosuppression treatments that are required when cells are transferred between genetically different individuals. This article provides some background to this field, a discussion of mechanisms and efficiency, and comments on prospects for future nuclear reprogramming research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gurdon, J B -- Melton, D A -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1811-5. doi: 10.1126/science.1160810.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Zoology, University of Cambridge, Cambridge CB2 12N, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095934" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Dedifferentiation ; Cell Differentiation ; Cell Fusion ; Cell Lineage ; *Cellular Reprogramming ; Cloning, Organism ; DNA/metabolism ; DNA-Binding Proteins/metabolism ; Embryonic Stem Cells/cytology/physiology ; Female ; Gene Expression ; Humans ; Male ; Nuclear Transfer Techniques ; Oocytes/cytology ; Pluripotent Stem Cells/cytology/physiology ; Regulatory Sequences, Nucleic Acid ; Transcription Factors/genetics/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Materials Research Society fall meeting. Protein chip promises cheaper diagnostics (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1784-5. doi: 10.1126/science.322.5909.1784b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095919" target="_blank"〉PubMed〈/a〉
    Keywords: Biomarkers, Tumor/*blood ; Blood Chemical Analysis/*methods ; Blood Proteins/*analysis ; Humans ; *Microfluidics ; Neoplasms/blood/diagnosis ; *Protein Array Analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Science policy. Report faults U.S. strategy for nanotoxicology research (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1779. doi: 10.1126/science.322.5909.1779a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095914" target="_blank"〉PubMed〈/a〉
    Keywords: Consumer Product Safety ; Humans ; Nanostructures/*toxicity ; *Nanotechnology ; National Academy of Sciences (U.S.) ; *Public Policy ; *Research ; Risk ; United States ; United States Government Agencies
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: Label-free chemical contrast is highly desirable in biomedical imaging. Spontaneous Raman microscopy provides specific vibrational signatures of chemical bonds, but is often hindered by low sensitivity. Here we report a three-dimensional multiphoton vibrational imaging technique based on stimulated Raman scattering (SRS). The sensitivity of SRS imaging is significantly greater than that of spontaneous Raman microscopy, which is achieved by implementing high-frequency (megahertz) phase-sensitive detection. SRS microscopy has a major advantage over previous coherent Raman techniques in that it offers background-free and readily interpretable chemical contrast. We show a variety of biomedical applications, such as differentiating distributions of omega-3 fatty acids and saturated lipids in living cells, imaging of brain and skin tissues based on intrinsic lipid contrast, and monitoring drug delivery through the epidermis.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576036/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576036/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Freudiger, Christian W -- Min, Wei -- Saar, Brian G -- Lu, Sijia -- Holtom, Gary R -- He, Chengwei -- Tsai, Jason C -- Kang, Jing X -- Xie, X Sunney -- CA113605/CA/NCI NIH HHS/ -- DP1 OD000277/OD/NIH HHS/ -- DP1 OD000277-05/OD/NIH HHS/ -- R01 CA113605/CA/NCI NIH HHS/ -- R01 CA113605-01A2/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1857-61. doi: 10.1126/science.1165758.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095943" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line, Tumor ; Corpus Callosum/chemistry/cytology ; Dimethyl Sulfoxide/administration & dosage/pharmacokinetics ; Eicosapentaenoic Acid/metabolism ; Epidermis/chemistry/metabolism/ultrastructure ; Humans ; Imaging, Three-Dimensional/*methods ; Lipids/*analysis ; Mice ; Microscopy/*methods ; Neurons/ultrastructure ; Sensitivity and Specificity ; Skin/chemistry/ultrastructure ; *Spectrum Analysis, Raman ; Tretinoin/administration & dosage/pharmacokinetics ; Vitamin A/analysis/chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: The host tissue microenvironment influences malignant cell proliferation and metastasis, but little is known about how tumor-induced changes in the microenvironment affect benign cellular ecosystems. Applying dynamic in vivo imaging to a mouse model, we show that leukemic cell growth disrupts normal hematopoietic progenitor cell (HPC) bone marrow niches and creates abnormal microenvironments that sequester transplanted human CD34+ (HPC-enriched) cells. CD34+ cells in leukemic mice declined in number over time and failed to mobilize into the peripheral circulation in response to cytokine stimulation. Neutralization of stem cell factor (SCF) secreted by leukemic cells inhibited CD34+ cell migration into malignant niches, normalized CD34+ cell numbers, and restored CD34+ cell mobilization in leukemic mice. These data suggest that the tumor microenvironment causes HPC dysfunction by usurping normal HPC niches and that therapeutic inhibition of HPC interaction with tumor niches may help maintain normal progenitor cell function in the setting of malignancy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Colmone, Angela -- Amorim, Maria -- Pontier, Andrea L -- Wang, Sheng -- Jablonski, Elizabeth -- Sipkins, Dorothy A -- 1DP2OD002160-01/OD/NIH HHS/ -- 5K08CA112126-02/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1861-5. doi: 10.1126/science.1164390.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Medicine, Section of Hematology/Oncology, University of Chicago, 5841 South Maryland Avenue MC 2115, Chicago, IL 60637, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095944" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigens, CD34/analysis ; Bone Marrow/*pathology ; Cell Count ; Cell Line, Tumor ; Cell Movement ; Chemokine CXCL12/metabolism ; Granulocyte Colony-Stimulating Factor/pharmacology ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/metabolism/*physiology ; Heterocyclic Compounds/pharmacology ; Humans ; Leukemia, Myeloid, Acute/metabolism/*pathology ; Mice ; Mice, SCID ; Neoplasm Transplantation ; Precursor B-Cell Lymphoblastic ; Leukemia-Lymphoma/metabolism/*pathology/physiopathology ; Stem Cell Factor/genetics/metabolism ; Stem Cell Niche/*pathology/physiopathology ; Transplantation, Heterologous ; Tumor Cells, Cultured
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Breakthrough of the year. The runners-up (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2008 Dec 19;322(5909):1768. doi: 10.1126/science.322.5909.1768.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095904" target="_blank"〉PubMed〈/a〉
    Keywords: Adipocytes, Brown/cytology/physiology ; Animals ; Electric Conductivity ; Embryo, Nonmammalian ; Genes, Neoplasm ; Genome ; Humans ; Motion Pictures as Topic ; Planets ; Proteins/chemistry/metabolism ; Protons ; *Science ; Sequence Analysis, DNA ; Water/chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 8
    facet.materialart.
    Unknown
    Video: reprogramming cells (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: This video introduction to Science's year-end special issue features Shinya Yamanaka of Kyoto University, George Daley of Harvard University, and Science's Gretchen Vogel reviewing some of the work that led studies in reprogramming cells to be tagged the top scientific story for 2008.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2008 Dec 19;322(5909):1766. doi: 10.1126/science.322.5909.1766b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095903" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cellular Reprogramming ; Embryonic Stem Cells ; Gene Expression Regulation ; Humans ; *Pluripotent Stem Cells ; Transcription Factors/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 9
    facet.materialart.
    Unknown
    Celebrating a year of Science (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1757. doi: 10.1126/science.1169562.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095901" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cellular Reprogramming ; Economics ; Humans ; *Planets ; *Science
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 10
    facet.materialart.
    Unknown
    Breakthrough of the year. Reprogramming Cells (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-12-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vogel, Gretchen -- New York, N.Y. -- Science. 2008 Dec 19;322(5909):1766-7. doi: 10.1126/science.322.5909.1766.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19095902" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; *Cellular Reprogramming ; Embryonic Stem Cells/cytology/physiology ; Humans ; Keratinocytes/cytology ; Pluripotent Stem Cells/cytology/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...