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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geriatrics. ; Aging. ; Biochemistry. ; Immunology. ; Microbiology. ; Geriatrics. ; Ageing. ; Biochemistry. ; Immunology. ; Microbiology.
    Description / Table of Contents: The Gut Microbiota and Its Metabolites Contribute to Ageing and Ageing-related Diseases -- Ageing and human gut microbiome: the taxonomic and functional transition towards an elderly-type microbiome -- Ageing of the gut microbiome and its potential contribution towards immunesenescence and inflammaging -- Gut Microbiome and Virome: Anti-aging interventions -- Bile microbiota profile in ageing and age-related disease. .
    Abstract: This edited volume studies gut microbiota peculiarities in elderly, in senescence-related and environmental-related alterations of gut microbiota in chronic diseases. Aging, as a physiological process mediated through several regulatory pathways and transcription factors, is generally speaking associated to a relentless functional decline and increasing risk of chronic diseases. Growing data on gut microbiota quali-quantitative changes in aging gut, and the opportunity to study by advanced NGS and metabolomic technologies, now offers novel horizons to link such changes to disease risks and to theoretically the weapons for gut microbiota intervention as an effective therapeutic tool. Chapters are divided into clear sections, starting with the aging perspective, then moving from chronic diseases to neurodegenerative diseases and cancer. The final parts focusses on interventions. Contributors are well-reputed and dedicated scientists in clinics and experimental medicine from 4 different continents who have provided their contribution keeping the polar star on aging as a guide while investigating their gut microbiota in occurrence and progression of disease together with proposed preventing, monitoring and therapeutic interventions. In the wide offer of books on gut microbiota, this age-thematic volume will be a valuable source of updated information for a wide group of readership including gerontologists, geriatricians, medical specialists of several fields, PhDs, basic scientists and public/private research entities focused on potential intervention in and through gut ecosystem. This book will stimulate a large number of basic scientists and clinicians to review their once organ (or cellular line)-specific knowledge and widen either their pathophysiological mechanisms understanding while providing novel ways to prevent, monitor and treat diseases from eyes to bones. .
    Type of Medium: Online Resource
    Pages: XI, 443 p. 42 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031140235
    Series Statement: Healthy Ageing and Longevity, 17
    DDC: 618.97
    Language: English
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  • 2
    Call number: 9/M 07.0421(332)
    In: Geological Society special publication
    Description / Table of Contents: Iterative comparison of analytical results and natural observations with predictions of numerical models improves interpretation of geological processes. Further refinements derive from wide-angle comparison of results from various scales of study. In this volume, advances from field, laboratory and modelling approaches to tectonic evolution from the lithosphere to the rock scale - are compared. Constructive use is made of apparently discrepant or non-consistent results from analytical or methodological approaches in processing field or laboratory data, P-T estimates, absolute or relative age determinations of tectonic events, tectonic unit size in crustal scale deformation, grain-scale deformation processes, various modelling approaches, and numerical techniques. Advances in geodynamic modelling critically depend on new insights into grain- and subgrain-scale deformation processes. Conversely, quantitative models help to identify which rheological laws and parameters exert the strongest control on multi-scale deformation up to lithosphere and upper mantle scale.
    Type of Medium: Monograph available for loan
    Pages: vii, 230 S.
    ISBN: 9781862392953
    Series Statement: Geological Society special publication 332
    Classification:
    Lithosphere
    Location: Reading room
    Branch Library: GFZ Library
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  • 3
    Keywords: geological processes; tectonics; numerical models
    Description / Table of Contents: Disequilibrium textures versus equilibrium modelling: geochronology at the crossroads / Igor M. Villa / Geological Society, London, Special Publications, 332, 1-15, 1 January 2010, https://doi.org/10.1144/SP332.1 --- Argon enters the retentive zone: reassessment of diffusion parameters for K-feldspar in the South Cyclades Shear Zone, Ios, Greece / M. A. Forster and G. S. Lister / Geological Society, London, Special Publications, 332, 17-34, 1 January 2010, https://doi.org/10.1144/SP332.2 --- Serrated quartz grain boundaries, temperature and strain rate: testing fractal techniques in a syntectonic granite / Manish A. Mamtani and R. O. Greiling / Geological Society, London, Special Publications, 332, 35-48, 1 January 2010, https://doi.org/10.1144/SP332.3 --- Microstructure and elastic anisotropy of naturally deformed leucogneiss from a shear zone in Montalto (southern Calabria, Italy) / Rosolino Cirrincione, Eugenio Fazio, Renée Heilbronner, Hartmut Kern, Kurt Mengel, Gaetano Ortolano, Antonino Pezzino and Rosalda Punturo / Geological Society, London, Special Publications, 332, 49-68, 1 January 2010, https://doi.org/10.1144/SP332.4 --- Geometry of intercrystalline brine in plastically deforming halite rocks: inference from electrical resistivity / Tohru Watanabe / Geological Society, London, Special Publications, 332, 69-78, 1 January 2010, https://doi.org/10.1144/SP332.5 --- Brittle plus plastic deformation of gypsum aggregates experimentally deformed in torsion to high strains: quantitative microstructural and texture analysis from optical and diffraction data / M. Zucali, V. Barberini, D. Chateigner, B. Ouladdiaf and L. Lutterotti / Geological Society, London, Special Publications, 332, 79-98, 1 January 2010, https://doi.org/10.1144/SP332.6 --- Numerical modelling of spontaneous slab breakoff dynamics during continental collision / Cyrill Baumann, Taras V. Gerya and James A. D. Connolly / Geological Society, London, Special Publications, 332, 99-114, 1 January 2010, https://doi.org/10.1144/SP332.7 --- Present-day vertical isostatic readjustment of the Western Alps revealed by numerical modelling and geodetic and seismotectonic data / Annalisa Gardi, Stéphane Baize and Oona Scotti / Geological Society, London, Special Publications, 332, 115-128, 1 January 2010, https://doi.org/10.1144/SP332.8 --- Block model versus thermomechanical model: new insights on the present-day regional deformation in the surroundings of the Calabrian Arc / Raffaele Splendore, Anna Maria Marotta, Riccardo Barzaghi, Alessandra Borghi and Letizia Cannizzaro / Geological Society, London, Special Publications, 332, 129-147, 1 January 2010, https://doi.org/10.1144/SP332.9 --- The role of mantle hydration in continental crust recycling in the wedge region / Marco Meda, Anna Maria Marotta and Maria Iole Spalla / Geological Society, London, Special Publications, 332, 149-172, 1 January 2010, https://doi.org/10.1144/SP332.10 --- Three-dimensional evaluation of fabric evolution and metamorphic reaction progress in polycyclic and polymetamorphic terrains: a case from the Central Italian Alps / Francesca Salvi, Maria Iole Spalla, Michele Zucali and Guido Gosso / Geological Society, London, Special Publications, 332, 173-187, 1 January 2010, https://doi.org/10.1144/SP332.11 --- The interaction of deformation and metamorphic reactions / Bruce E. Hobbs, Alison Ord, Maria Iole Spalla, Guido Gosso and Michele Zucali / Geological Society, London, Special Publications, 332, 189-223, 1 January 2010, https://doi.org/10.1144/SP332.12
    Pages: Online-Ressource (VII, 230 Seiten) , Illustrationen, Diagramme, Karten
    ISBN: 9781862395800
    Language: English
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  • 4
    Publication Date: 2023-06-17
    Description: We provide a database of the coseismic surface ruptures produced by the 21 August 2017 Md 4.0 earthquake that struck the Casamicciola Terme village in the north of Ischia volcanic island (Italy). Despite its small size, the earthquake caused two fatalities and heavy damages in a restricted area of a few square kilometers. The shallow hypocentral depth of the earthquake caused a significant coseismic surface faulting, testified by a main alignment of ruptures mapped for a 2 km end-to-end length along the Casamicciola E-W trending normal fault system, bounding the northern slope of Mt. Epomeo. Casamicciola Terme has been recurrently destroyed in the last centuries by similar volcano-tectonic earthquakes (1762, 1767, 1796, 1828, 1881, and 1883). After the catastrophic 1883 Casamicciola event (2343 casualties), this is the first heavy damaging earthquake at Ischia that provides, for the first time, the opportunity of integrating historical seismicity, macroseismic observations, instrumental information, and detailed mapping of coseismic geological effects. We performed a detailed field surveys in the epicentral region of the 21 August earthquake to describe the ruptures geometry and kinematics of the seismogenetic fault responsible of the earthquake with the aim of contributing to the seismic hazard evaluation and land use planning in the Ischia island, one of the most crowded touristic destinations worldwide. Summarizing our study of ground effects for the 21 August 2017 earthquake is important for improving knowledge on surface earthquake in the volcanic area and contributing to complete the gap of empirical scaling relating to the surface-faulting mechanism due to small-size or moderate earthquakes in volcano-tectonic framework. The collected field observations result in a dataset of 88 georeferenced records describing coseismic ruptures/fractures by features as ID number, time of sample collection, location (latitude, longitude, elevation), type of rupture, type of affected substratum, attitude (dip angle, dip direction, strike), surface offset (opening, throw, strike slip, net slip), kinematics, slip vector attitude, width of the deformation zone.
    Keywords: Casamicciola_Terme_coseismic_ruptures; Casamicciola fault; coseismic rupture; DATE/TIME; Direction; earthquake; ELEVATION; Ischia, Italy; Ischia island; Kinematics; LATITUDE; Length; LONGITUDE; Observation; Opening; ORDINAL NUMBER; Strike; Substrate type; Throw; UTM Easting, Universal Transverse Mercator; UTM Northing, Universal Transverse Mercator; volcano-tectonic
    Type: Dataset
    Format: text/tab-separated-values, 775 data points
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 34 (1995), S. 3655-3662 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 33 (1994), S. 1385-1391 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 62 (1940), S. 2767-2770 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 289-292 (Aug. 1998), p. 613-622 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 29 (1986), S. 717-719 
    ISSN: 1432-1041
    Keywords: sulphinpyrazone ; oxprenolol ; antihypertensive activity ; cyclo-oxygenase ; prostaglandins ; drug interaction ; drug metabolizing enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The interfering effect of sulphinpyrazone, a uricosuric agent which reduces the activity of cyclo-oxygenase, with the antihypertensive activity of oxprenolol, a non-cardioselective beta-blocker with sympathomimetic activity, has been evaluated. Ten patients with primary arterial hypertension of mild to moderate degree entered a randomized doubleblind cross-over study versus placebo. They were given oxprenolol + placebo or oxprenolol + sulphinpyrazone for 15 days, and then the treatments were crossed-over for a further 15 days. Oxprenolol significantly reduced blood pressure (161±3/101±1 vs 149±4/96±2 mmHg) and heart rate (72±3 vs 66±3 beats/min). During administration of the combination with sulphinpyrazone the blood pressure increased to its pretreatment level (156±5/101±2 mmHg). The effect of oxprenolol on heart rate was not influenced by the combined treatment (67±6 beats/min). The results may be explained by 1) sulphinpyrazone-induced inhibition of prostaglandin synthesis, which could interfere with the antihypertensive activity of oxprenolol, or 2) sulphinpyrazone-induced acceleration of the metabolism of oxprenolol.
    Type of Medium: Electronic Resource
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