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  • 11
    Publication Date: 2019-07-17
    Description: Periodically appearing amorphous aggregates, 'marine snow', are formed in the sea and if settled as mats on the sea bottom cause death of benthic metazoans. Especially those animals are killed which are sessile filter feeders, e.g. sponges, mussels, or Anthozoa. The etiology of the toxic principle(s) is not yet well understood. Gel-like marine snow aggregates occurred in the Northern Adriatic during summer 1997. Samples of these aggregates were collected during the period July to September and the outer as well as the inner zones were analyzed for (i) cell toxicity, and (ii) chemosensitizing activity of the multixenobiotic resistance (MXR) mechanism. Organic extracts were prepared and cell toxicity was determined using mouse lymphoma cells. The experiments revealed that the major activity is seen in the center of the mats of the gel-like aggregates; a growth inhibitory activity of up to 54% (correlated to 5 ml of snow sample) was determined. The same extracts were used to determine the inhibition of the P-glycoprotein (Pgp) extrusion pump which confers the multixenobiotic resistance. The analyses were performed with cells from the sponge Suberites domuncula and with gills from the clam Corbicula fluminea in situ. Both systems have been shown to express the Pgp extrusion pump. The data show that extracts from the outer zone of the gel-like aggregate samples display pronounced inhibitory activity on the MXR extrusion pump and hence act as chemosensitizers by reversing the MXP property. These findings indicate that gel-like aggregates contain compounds in the outer zone, chemosensitizer of the Pgp extrusion pump, which lower the level of protection of metazoan animals towards dissolved compounds in their surrounding milieu, and in the center toxic compounds which are--very likely--even in the absence of chemosensitizers hazardous for the invertebrates.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 12
    Publication Date: 2021-03-29
    Description: Vergleichende Betrachtungen der neuesten Untersuchungsergebnisse in verschiedenen Marschgebieten Niedersachsens und der Niederlande führen zu der Feststellung, daß trotz örtlich sehr unterschiedlicher Einflüsse auf das Sedimentationsgeschehen der Aufbau der holozänen Schichten von überregional wirksamen Faktoren bestimmt sein muß. Der Aufbau der holozänen Schichten im südlichen Nordseeküstengebiet wird vor allem durch die von glazialeustatischen Meeresspiegelbewegungen bedingte Meerestransgression bestimmt. Einflüsse tektonischer Krustenbewegungen und anderer Faktoren sind demgegenüber nur von untergeordneter Bedeutung. Der Ablauf der holozänen Meerestransgression an der südlichen Nordseeküste wird auf Grund von 57 Radiokarbondatierungen und umfangreicher Kartierungsarbeiten in einem Diagramm dargestellt. Es gibt unter größtmöglicher Berücksichtigung der Sedimentsetzungen die mittleren Hochwasserstände zu den verschiedenen Zeitperioden wieder. Stärkere Anstiegsbewegungen des Meeresspiegels treten im Präboreal (8000—6750 v. Chr.), im Atlantikum (5500—2500 v. Chr.) und im Subatlantikum (ab 300 v. Chr.) bis heute auf. Die umgekehrten Tendenzen sind im Boreal (6750—5500 v. Chr.) und im Subboreal (2500—300 v. Chr.) festzustellen. Diese Verlangsamungen bzw. Unterbrechungen des Transgressionsablaufes sind in etwa zeitgleich mit bedeutenden Gletscherregenerationen auf dem nordamerikanischen Kontinent. Diese beiden bedeutendsten Einschnitte in der Kurve des holozänen Transgressionsablaufes im Boreal und Subboreal werden zu einer Untergliederung des Holozäns in 3 Unterabteilungen verwendet (Alt-, Mittel-, Jungholozän). Innerhalb dieser Unterabteilungen werden dann jeweils eine untere Stufe (Transgressionsbeschleunigung) und eine obere Stufe (Transgressionsverlangsamung) unterschieden. Im Jungholozän stehen wir z. Zt. noch in der unteren Stufe. Weitere Untergliederungen ergeben sich aus der Ausscheidung kleinerer Schwankungen des Transgressionsverlaufes, wobei im unteren Mittelholozän 3 Folgen, im oberen Mittelholozän 2 Folgen und im Jungholozän 4 Folgen unterschieden werden können. Jede dieser Folgen setzt sich aus einem Überflutungs- und einem Verlandungsabschnitt zusammen.
    Description: research
    Keywords: 551.7 ; VAR 000 ; Glazialgeologie ; niedersachsen ; nordseeküste ; holozän ; niederlande ; geochronologie ; meerestransgression ; holozängliederung ; marschgebiet ; sedimentation ; krustenbewegung ; meeresspiegelbewegung ; radiokarbondatierung ; hochwasserstand
    Language: German
    Type: article , publishedVersion
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  • 13
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    In:  EPIC310th European Workshop on Laser-Ablation in Elemental and Isotopic Analysis, Kiel, Germany, June 29-July 1, 2010 p.
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 14
    Publication Date: 2022-08-05
    Description: This work documents the ICON‐Earth System Model (ICON‐ESM V1.0), the first coupled model based on the ICON (ICOsahedral Non‐hydrostatic) framework with its unstructured, icosahedral grid concept. The ICON‐A atmosphere uses a nonhydrostatic dynamical core and the ocean model ICON‐O builds on the same ICON infrastructure, but applies the Boussinesq and hydrostatic approximation and includes a sea‐ice model. The ICON‐Land module provides a new framework for the modeling of land processes and the terrestrial carbon cycle. The oceanic carbon cycle and biogeochemistry are represented by the Hamburg Ocean Carbon Cycle module. We describe the tuning and spin‐up of a base‐line version at a resolution typical for models participating in the Coupled Model Intercomparison Project (CMIP). The performance of ICON‐ESM is assessed by means of a set of standard CMIP6 simulations. Achievements are well‐balanced top‐of‐atmosphere radiation, stable key climate quantities in the control simulation, and a good representation of the historical surface temperature evolution. The model has overall biases, which are comparable to those of other CMIP models, but ICON‐ESM performs less well than its predecessor, the Max Planck Institute Earth System Model. Problematic biases are diagnosed in ICON‐ESM in the vertical cloud distribution and the mean zonal wind field. In the ocean, sub‐surface temperature and salinity biases are of concern as is a too strong seasonal cycle of the sea‐ice cover in both hemispheres. ICON‐ESM V1.0 serves as a basis for further developments that will take advantage of ICON‐specific properties such as spatially varying resolution, and configurations at very high resolution.
    Description: Plain Language Summary: ICON‐ESM is a completely new coupled climate and earth system model that applies novel design principles and numerical techniques. The atmosphere model applies a non‐hydrostatic dynamical core, both atmosphere and ocean models apply unstructured meshes, and the model is adapted for high‐performance computing systems. This article describes how the component models for atmosphere, land, and ocean are coupled together and how we achieve a stable climate by setting certain tuning parameters and performing sensitivity experiments. We evaluate the performance of our new model by running a set of experiments under pre‐industrial and historical climate conditions as well as a set of idealized greenhouse‐gas‐increase experiments. These experiments were designed by the Coupled Model Intercomparison Project (CMIP) and allow us to compare the results to those from other CMIP models and the predecessor of our model, the Max Planck Institute for Meteorology Earth System Model. While we diagnose overall satisfactory performance, we find that ICON‐ESM features somewhat larger biases in several quantities compared to its predecessor at comparable grid resolution. We emphasize that the present configuration serves as a basis from where future development steps will open up new perspectives in earth system modeling.
    Description: Key Points: This work documents ICON‐ESM 1.0, the first version of a coupled model based on the ICON framework. Performance of ICON‐ESM is assessed by means of CMIP6 Diagnosis, Evaluation, and Characterization of Klima experiments at standard CMIP‐type resolution. ICON‐ESM reproduces the observed temperature evolution. Biases in clouds, winds, sea‐ice, and ocean properties are larger than in MPI‐ESM.
    Description: European Union H2020 ESM2025
    Description: European Union H2020 COMFORT
    Description: European Union H2020ESiWACE2
    Description: Deutsche Forschungsgemeinschaft TRR181
    Description: Deutsche Forschungsgemeinschaft EXC 2037
    Description: European Union H2020
    Description: Deutscher Wetterdienst
    Description: Bundesministerium fuer Bildung und Forschung
    Description: http://esgf-data.dkrz.de/search/cmip6-dkrz/
    Description: https://mpimet.mpg.de/en/science/modeling-with-icon/code-availability
    Description: http://cera-www.dkrz.de/WDCC/ui/Compact.jsp?acronym=RUBY-0_ICON-_ESM_V1.0_Model
    Keywords: ddc:550.285 ; ddc:551.63
    Language: English
    Type: doc-type:article
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  • 15
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 15 (1976), S. 958-961 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 16
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 17
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 20 (1981), S. 337-344 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 19
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 20
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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