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  • 1
    Electronic Resource
    Electronic Resource
    Enhanced 140Ba/140La excretion provoked by a cryptating agent in the rat (1977)
    Springer
    Naturwissenschaften 64 (1977), S. 96-97 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00437361
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  • 2
    Electronic Resource
    Electronic Resource
    New aspects of the high spin-low spin transition in tris(2-methyl-1,10-phenanthroline)iron(II) perchlorate (1976)
    s.l. : American Chemical Society
    Inorganic chemistry 15 (1976), S. 958-961 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50158a046
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  • 3
    Electronic Resource
    Electronic Resource
    Hexachlorobenzene contamination in laboratory monkey chow (1976)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 24 (1976), S. 563-565 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf60205a067
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  • 4
    Electronic Resource
    Electronic Resource
    Thymine content of sea water as a measure of biosynthetic potential (1977)
    Springer
    Marine biology 40 (1977), S. 1-8 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A hydrolysis procedure along with a high-pressure liquid chromatographic procedure is given enabling simple and reliable thymine determinations in the nanogram range in different fractions of sea-water samples taken from three different locations in the Northern Adriatic Sea. The levels corresponded to 1–3 μg DNA per liter. From total polyanionic thymine, which had been precipitated as the cetyltrimethylammonium salt, the highest percentage was linked to the particulate fraction, with a definite subsurface minimum at 10 to 15 m. There was a corresponding maximum of a high molecular “non-particulate” thymine-containing fraction at the corresponding depth. From the bottom at 30 m upwards to about 20 m, a low molecular thymine-containing material has been found. Remarkably these basic features were common to all three locations, one of which was supposed to be in clean water, one near a thickly settled, touristic area, and the other in front of a large river delta coming from industrial hinterland.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00390621
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  • 5
    Electronic Resource
    Electronic Resource
    Benzo(a)pyrene monooxygenase induction in marine fish-molecular response to oil pollution (1977)
    Springer
    Marine biology 44 (1977), S. 211-216 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Induction of benzo (a) pyrene monooxygenase (BPMO) activity occurred in Blennius pavo, a species with a restricted territorial range, in response to exposure to a Diesel 2 oil. A response delay of 14 days was found at a concentration of 170 ppb and of 3 days when the water was saturated with Diesel 2 oil. When induced fish were transferred to clean water, elevated BPMO activity was maintained at a high level for at least a month. A benthic protochordate, Microcosmos sulcatus, showed no increase in BPMO activity when exposed to these concentrations even after 30 days of exposure. Field observations revealed a great variation in the BPMO activity from B. pavo caught at different sites. Fish from contaminated sites had significantly elevated levels of BPMO activity. Sardine schools caught at different sites had different, low levels of BPMO activities. However, specimens from the same school had closely similar levels of enzyme activity. An oil pollution incident (New Year 1977 oil spill in Northern Adriatic Sea) caused an increase in the BPMO activity in the livers of Blenniideae, reaching a peak on the 23rd day (representing an 8.5-fold increase in the background level), followed by a decrease in activity until a new background level, 3 times that of the original background level, was reached on the 45th day. This new background level is constant (through May-5 months after the incident). Measurement of BPMO activity in the livers of nonmigrant fish could serve as a useful biochemical parameter for monitoring and evaluation of acute or long-term oil pollution at a given site.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00387701
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  • 6
    Electronic Resource
    Electronic Resource
    Disposition of valproic acid in patients with liver disease (1978)
    Springer
    European journal of clinical pharmacology 13 (1978), S. 55-60 
    Details
    ISSN: 1432-1041
    Keywords: Valproic acid ; pharmacokinetics ; liver disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The disposition of valproic acid (di-n-propylacetate; VA) has been studied after a single oral dose of a solution of 450 mg in 7 patients with alcoholic cirrhosis and in 4 patients recovering from acute hepatitis. The diagnosis was based on biochemical function tests and histological findings. The pharmacokinetic parameters were compared with those reported for healthy volunteers. VA in therapeutic concentration (80 µg/ml) in plasma was less bound to plasma proteins in patients with alcoholic cirrhosis (70.7±11.3%) and in patients recovering from acute hepatitis (78.1±14.1%) than in controls (88.7±5.2%). The reduced binding affected the blood/plasma concentration ratio and the apparent distribution volume Vd(β); the latter was increased from the normal value of 0.14±0.05 l/kg to 0.22±0.09 (p〈0.05) in alcoholic cirrhotics, and to 0.20±0.07 (p=0.056) in patients recovering from acute hepatitis. The half-life of elimination T1/2 (β) (controls=12.2±3.7 h) was significantly (p〈0.05) prolonged in cirrhotics (18.9±5.1 h) and in patients recovering from acute hepatitis (17.0±3.7 h). The plasma $$\overline {Cl} $$ of total drug was not impaired, which can best be explained by the lower plasma protein binding, which might have increased the $$\overline {Cl} $$ of this drug which shows restricted clearance. In addition, the plasma $$\overline {Cl} $$ of free drug was significantly (p〈0.02) reduced in alcoholic cirrhotics. During a two day urine collection no measurable amount of unchanged VA was recovered. There was considerable excretion of VA-conjugates, which could be hydrolyzed either by HCl or by β-glucuronidase/arylsulphatase (4–23% of the dose). These percentages were in the same range as in normals (26.7±16.1%). The study indicates that elimination of VA is slightly impaired in patients with dysfunction of the liver.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00606683
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  • 7
    Electronic Resource
    Electronic Resource
    Mixed-layer characteristics in real humite structures (1978)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 34 (1978), S. 607-609 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Transmission electron micrographs resolving (100) lattice fringes of clinohumite revealed faults parallel to (100). A simplified model of humite minerals, which interprets them as layers of forsterite and brucite-sellaite, was used for analysis of the faults. These compositional faults produce one or two unit layers of humite and/or chondrodite interlayered between the regular sequence of clinohumite along a*. Thus, nonstoichiometric compositions of humite minerals can be explained as mixed layers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739478001278
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  • 8
    Electronic Resource
    Electronic Resource
    INHIBITION OF HERPESVIRUS DNA SYNTHESIS BY 9-β-D-ARABINOFURANOSYLADENINE IN CELLULAR AND CELL-FREE SYSTEMS 〈link href="#fn"〉*〈/link〉 (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 284 (1977), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1977.tb21935.x
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  • 9
    Electronic Resource
    Electronic Resource
    Lamellar intergrowth of orthoenstatite and clinoenstatite [(Mg,Fe)SiO3] studied by lattice imaging (1975)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 8 (1975), S. 212-212 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Deformation experiments under high static confining pressure and observations on tectonically deformed specimens have shown that orthoenstatite (space group Pbca) can be transformed to clinoenstatite (P21/c) by shear stress. The specimen used for the present study was prepared by ion-thinning from an orthoenstatite sample deformed at 800°C and 5 kb confining pressure at a strain rate of 10−4s−1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889875010230
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  • 10
    Electronic Resource
    Electronic Resource
    Chemical and crystallographic study of cronstedtite in the matrix of the Cochabamba (CM2) carbonaceous chondrite (1979)
    Springer
    Mineralogy and petrology 26 (1979), S. 293-304 
    Details
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Zusammenfassung Der Hauptbestandteil der Matrix im kohligen Chondrit Cochabamba ist ein Schichtsilikat, das hauptsächlich aufgrund seiner chemischen Zusammensetzung als Cronstedtit identifiziert wurde. Die idealisierte Formel entspricht ungefähr M6Fe 0.7 +3 Al0.5Si2.7O10(OH)8 mit M=Fe2+, Fe3+ und Mg in wechselnden Mengen. TEM-Untersuchungen zeigen das Vorkommen von drei Modifikationen, sowie einen hohen Grad von Versetzungsfehlern parallel zu (001), mit dem Versetzungsfaktor ±b/3 oder ±2b/3. Deformierte amorphe Aggregate in der Matrix scheinen primitive Bausteine der Schichtsilikate zu sein. Sie (und nicht die wasserfreien Mineralien) dürften das Material darstellen, aus dem Cronstedtit gebildet wurde. Die Bildungsbedingungen von Cronstedtit werden diskutiert. Außerdem wird über Beobachtungen an anderen Matrixmineralien berichtet.
    Notes: Summary The principal mineral component in the matrix of the Cochabamba carbonaceous chondrite is a phyllosilicate, which is identified as cronstedtite mainly on the basis of its chemical composition. Its approximate idealized formula is given by M6 Fe 0.7 3+ Al0.5Si2.7O10 (OH)8 with M=Fe2+, Fe3+, and Mg in somewhat variable amounts. TEM studies reveal the presence of three polytypes, and show a high degree of stacking disorder parallel to (001) with the displacement vector ±b/3 or ±2b $$\bar 3$$ . Crumpled amorphous masses in the matrix may contain structural building blocks of phyllosilicates. They, rather than the anhydrous minerals, seem to be the most likely progenitors of cronstedtite. Some constraints on its origin are reviewed. In addition to cronstedtite, observations on some other matrix phases are also reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01089843
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