ISSN:
1662-9752
Quelle:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Thema:
Maschinenbau
Notizen:
A novel nano-hydroxyapatite/chitosan (n-HA/CS) composite scaffold with high porositywas developed by a new method of emulsion-foaming/freeze-drying process and was characterizedby means of infrared spectroscopy (IR), scanning electronic microscopy (SEM) and universalmaterial testing machine. In addition, the porosity and density of the scaffold were also calculated.IR result shows that the characteristic absorption peaks belonging to both CS and HA are present intheir composite, and the slight band-shifts and peak-decrease suggest that some interactions havetaken place between the two phases of CS and n-HA in the composite. SEM photo displays that,with the dosage increase of Tween-80, the prepared scaffold shows highly porous andinterconnected structure, in which macropores and micropores coexist. The calculated datademonstrate that the porosity of the scaffold is proportional to the content of the emulsifier, whilethe compressive strength is inversely. When 15wt% emulsifier used, the porosity of the scaffold canbe up to 90% and the density is 0.453g/cm3, while the corresponding compressive strength is about2.4MPa. The newly developed n-HA/CS composite scaffolds may serve as a good 3-D substrate forcell attachment and migration in bone tissue engineering
Materialart:
Digitale Medien
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/02/15/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.544-545.789.pdf
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