ISSN:
1040-7685
Keywords:
multidimensional
;
supercritical fluid chromatography
;
liquid crystal polysiloxane
;
polycyclic aromatic hydrocarbons
;
coal tar
;
petroleum distillate
;
carbofuran
;
capillary columns
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A multidimensional system based on capillary supercritical fluid chromatography (SFC) was constructed that utilizes a simple flow-switching interface between two open-tubular 50-μm i.d. columns. A novel solvent-venting injection technique was incorporated in the system that enables single or multiple 0.5-μL volumes to be injected into an uncoated, yet deactivated, length of capillary precolumn without flooding of the analytical column. The effectiveness of multidimensional capillary SFC (SFC-SFC) for complex mixtures is demonstrated by the analysis of polycyclic aromatic hydrocarbons (PAH) in a coal tar extract, the trace determination of a methylcarbamate pesticide and its metabolites in a bird extract, and a group-type separation of hydrocarbons in a high-boiling petroleum distillate. These examples show for the first time that capillary SFC-SFC is a complementary alternative to other multidimensional chromatographic methods involving liquid or gaseous mobile phases.
Additional Material:
12 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mcs.1220010206
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