ISSN:
1040-7685
Keywords:
unified chromatography
;
gas chromatography
;
supercritical fluid chromatography
;
open tubular columns
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Band broadening brought about by changing the mobile phase from the GC mode to the SFC mode in unified chromatography is discussed. Its origin is shown to result from several factors: the replaceable volume of the tubing and valves in front of and following the column; the volume, internal diameter, and film thickness of the open tubular column; the initial pressure of the supercritical mobile phase; and the column temperature. Improvements to restrict band broadening were achieved by optimizing the system and its operating conditions.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mcs.1220050308
